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14 values
Q22.678
Q22
What is Ingrezza?
Ingrezza, also known generically as Valbenazine Tosylate, was approved by the FDA in 2017 to treat movement disorder. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_5423', 'tradeNames_string': 'Ingrezza', 'drugName': 'Valbenazine Tosylate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Synaptic vesicular amine transporter inhibitor', 'linkedDiseasesDrug_string': 'Movement Disorder (EFO_0004280)', 'newL...
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Q22.346
Q22
What is Lenvima?
Lenvima, also known generically as Lenvatinib Mesylate, was approved by the FDA in 2015 to treat renal cell carcinoma, thyroid carcinoma, and thyroid cancer. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_3026', 'tradeNames_string': 'Lenvima', 'drugName': 'Lenvatinib Mesylate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Vascular endothelial growth factor receptor inhibitor', 'linkedDiseasesDrug_string': 'Cancer (MONDO_0004992), Neoplasm (...
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Q22.3
Q22
What is Yonsa?
Yonsa, also known generically as Abiraterone Acetate, was approved by the FDA in 2011 to treat metastatic prostate cancer, cancer, neoplasm, prostate adenocarcinoma, prostate carcinoma, and prostate cancer. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_2354', 'tradeNames_string': 'Yonsa, Zytiga', 'drugName': 'Abiraterone Acetate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Cytochrome P450 17A1 inhibitor', 'linkedDiseasesDrug_string': 'Cancer (MONDO_0004992), Prostate Cancer (MONDO_0008...
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Q22.231
Q22
What is Steglatro?
Steglatro, also known generically as Ertugliflozin, was approved by the FDA in 2017 to treat diabetes mellitus and type 2 diabetes mellitus. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_3216', 'tradeNames_string': 'Steglatro', 'drugName': 'Ertugliflozin', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Sodium/glucose cotransporter 2 inhibitor', 'linkedDiseasesDrug_string': 'Diabetes Mellitus (EFO_0000400), Type 2 Diabetes Me...
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Q22.84
Q22
What is Bevyxxa?
Bevyxxa, also known generically as Betrixaban, was approved by the FDA in 2017 to treat Recurrent thrombophlebitis and venous thromboembolism. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_5169', 'tradeNames_string': 'Bevyxxa', 'drugName': 'Betrixaban', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Coagulation factor X inhibitor', 'linkedDiseasesDrug_string': 'Recurrent Thrombophlebitis (HP_0004419), Atrial Flutter (EFO_00039...
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Q22.480
Q22
What is Isturisa?
Isturisa, also known generically as Osilodrostat Phosphate, was approved by the FDA in 2020 to treat pituitary-dependent Cushing's disease. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_5216', 'tradeNames_string': 'Isturisa', 'drugName': 'Osilodrostat Phosphate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Cytochrome P450 11B1 inhibitor', 'linkedDiseasesDrug_string': "Pituitary-Dependent Cushing'S Disease (EFO_1001110)",...
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Q22.701
Q22
What is Prialt?
Prialt, also known generically as Ziconotide, was approved by the FDA in 2004 to treat Fever and pain. It is a protein therapy that acts as a(n) blocker.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_2513', 'tradeNames_string': 'Prialt', 'drugName': 'Ziconotide', 'drugMolecularType': 'Protein', 'drugActionType': 'blocker', 'drugMechanismOfAction': 'Voltage-gated N-type calcium channel alpha-1B subunit blocker', 'linkedDiseasesDrug_string': 'Pain (EFO_0003843), Fever (HP_0001945)', 'new...
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Q22.672
Q22
What is Triptodur Kit?
Triptodur Kit, also known generically as Triptorelin Pamoate, was approved by the FDA in 2000 to treat prostate adenocarcinoma, prostate carcinoma, Central precocious puberty, and precocious puberty. It is a protein therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4710', 'tradeNames_string': 'Trelstar, Triptodur kit', 'drugName': 'Triptorelin Pamoate', 'drugMolecularType': 'Protein', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Gonadotropin-releasing hormone receptor agonist', 'linkedDiseasesDrug_string': 'Central Precocious Puberty (EFO_0...
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Q22.611
Q22
What is Nucynta?
Nucynta, also known generically as Tapentadol Hydrochloride, was approved by the FDA in 2008 to treat Chronic pain, pain, and neuropathic pain. It is a small molecule therapy that acts as a(n) agonist and inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_6372', 'tradeNames_string': 'Nucynta, Nucynta er, Palexia', 'drugName': 'Tapentadol Hydrochloride', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Mu opioid receptor agonist', 'linkedDiseasesDrug_string': 'Pain (EFO_0003843), Chronic Pain (HP_...
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Q22.123
Q22
What is Carnexiv?
Carnexiv, also known generically as Carbamazepine, was approved by the FDA in 1968 to treat Seizure, bipolar disorder, epilepsy, partial epilepsy, bipolar I disorder, and trigeminal neuralgia. It is a small molecule therapy that acts as a(n) blocker.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_5883', 'tradeNames_string': 'Arbil mr, Carbagen sr, Carbamazepine, Carbatrol, Carnexiv, Epimaz, Epimaz ret, Epitol, Equetro, Sirtal ret, Tegretol, Tegretol Xr, Tegretol chewtab, Tegretol prolonged release, Tegretol-xr, Teril, Teril ret, Timonil 200 ret, Timonil 400 ret', 'drugName': 'Carba...
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Q22.315
Q22
What is Fanapt?
Fanapt, also known generically as Iloperidone, was approved by the FDA in 2009 to treat psychosis and schizophrenia. It is a small molecule therapy that acts as a(n) antagonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4312', 'tradeNames_string': 'Fanapt, Iloperidone', 'drugName': 'Iloperidone', 'drugMolecularType': 'Small molecule', 'drugActionType': 'antagonist', 'drugMechanismOfAction': 'Serotonin 2a (5-HT2a) receptor antagonist', 'linkedDiseasesDrug_string': 'Psychosis (EFO_0005407), Post-Traumatic S...
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Q22.207
Q22
What is Angeliq?
Angeliq, also known generically as Drospirenone, was approved by the FDA in 2001 to treat acne. It is a small molecule therapy that acts as a(n) agonist and antagonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_1555', 'tradeNames_string': 'Angeliq, Slynd', 'drugName': 'Drospirenone', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Progesterone receptor agonist', 'linkedDiseasesDrug_string': 'Polycystic Ovary Syndrome (EFO_0000660), Binge Eating (EFO_0...
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Q22.248
Q22
What is Uloric?
Uloric, also known generically as Febuxostat, was approved by the FDA in 2009 to treat gout and hyperuricemia. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_1230', 'tradeNames_string': 'Adenuric, Uloric', 'drugName': 'Febuxostat', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Xanthine dehydrogenase inhibitor', 'linkedDiseasesDrug_string': 'Gout (EFO_0004274), Hyperuricemia (EFO_0009104), Angina...
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Q22.693
Q22
What is Lupkynis?
Lupkynis, also known generically as Voclosporin, was approved by the FDA in 2021 to treat immune system disease and lupus nephritis. It is a protein therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_3543', 'tradeNames_string': 'Lupkynis', 'drugName': 'Voclosporin', 'drugMolecularType': 'Protein', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Serine/threonine protein phosphatase 2B catalytic subunit, alpha isoform inhibitor', 'linkedDiseasesDrug_string': 'Uveitis (EFO_100123...
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Q22.275
Q22
What is Trelegy Ellipta?
Trelegy Ellipta, also known generically as Fluticasone Furoate, was approved by the FDA in 2007 to treat Nasal congestion, Airway obstruction, chronic obstructive pulmonary disease, seasonal allergic rhinitis, allergic rhinitis, Rhinitis, Allergic, Perennial, and asthma. It is a small molecule therapy that acts as a(n)...
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_1921', 'tradeNames_string': 'Arnuity ellipta, Avamys, Flonase sensimist allergy relief, Relvar ellipta, Trelegy ellipta, Veramyst', 'drugName': 'Fluticasone Furoate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Glucocorticoid receptor agoni...
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Q22.134
Q22
What is Zerviate?
Zerviate, also known generically as Cetirizine Hydrochloride, was approved by the FDA in 1995 to treat seasonal allergic rhinitis, urticaria, and allergic rhinitis. It is a small molecule therapy that acts as a(n) antagonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_6377', 'tradeNames_string': "Allacan, Allertek, Becoallergy, Cetec, Cetirizine hydrochloride, Cetirizine hydrochloride allergy, Cetirizine hydrochloride hives, Cetirizine hydrochloride hives relief, Cetirocol, Children's cetirizine hydrochloride allergy, Children's cetirizine hydrochloride...
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Q22.687
Q22
What is Verquvo?
Verquvo, also known generically as Vericiguat, was approved by the FDA in 2021 to treat cardiovascular disease and heart failure. It is a small molecule therapy that acts as a(n) activator.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_2605', 'tradeNames_string': 'Verquvo', 'drugName': 'Vericiguat', 'drugMolecularType': 'Small molecule', 'drugActionType': 'activator', 'drugMechanismOfAction': 'Soluble guanylate cyclase activator', 'linkedDiseasesDrug_string': 'Heart Failure (EFO_0003144), Coronary Artery Disease (EFO_000...
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Q22.61
Q22
What is Onureg?
Onureg, also known generically as Azacitidine, was approved by the FDA in 2004 to treat Thrombocytopenia, myelodysplastic syndrome, cancer, neoplasm, refractory anemia with excess blasts, chronic myelomonocytic leukemia, and anemia. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4131', 'tradeNames_string': 'Azacitidine, Onureg, Vidaza', 'drugName': 'Azacitidine', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'DNA (cytosine-5)-methyltransferase 1 inhibitor', 'linkedDiseasesDrug_string': 'Cancer (MONDO_0004992), Multi...
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Q22.314
Q22
What is Zydelig?
Zydelig, also known generically as Idelalisib, was approved by the FDA in 2014 to treat chronic lymphocytic leukemia, neoplasm of mature B-cells, cancer, neoplasm, and non-Hodgkins lymphoma. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_3742', 'tradeNames_string': 'Zydelig', 'drugName': 'Idelalisib', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'PI3-kinase p110-delta subunit inhibitor', 'linkedDiseasesDrug_string': 'Amyloidosis (EFO_1001875), Cancer (MONDO_0004992), Multip...
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Q22.31
Q22
What is Firdapse?
Firdapse, also known generically as Amifampridine Phosphate, was approved by the FDA in 2018. It is a small molecule therapy that acts as a(n) blocker.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_3435', 'tradeNames_string': 'Firdapse', 'drugName': 'Amifampridine Phosphate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'blocker', 'drugMechanismOfAction': 'Voltage-gated potassium channel blocker', 'linkedDiseasesDrug_string': 'Myasthenia Gravis (EFO_0004991), Brugada Synd...
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Q22.70
Q22
What is Colazal?
Colazal, also known generically as Balsalazide Disodium, was approved by the FDA in 2000 to treat ulcerative colitis. It is a small molecule therapy that acts as a(n) agonist and inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_1296', 'tradeNames_string': 'Balsalazide disodium, Colazal, Colazide, Giazo', 'drugName': 'Balsalazide Disodium', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Peroxisome proliferator-activated receptor gamma agonist', 'linkedDiseasesDrug_str...
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Q22.658
Q22
What is Ryzolt?
Ryzolt, also known generically as Tramadol Hydrochloride, was approved by the FDA in 1995 to treat Chronic pain, pain, and drug dependence. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_3268', 'tradeNames_string': 'Aceon, Conzip, Dromadol sr, Dromadol xl, Invodol sr, Larapam sr, Mabron, Maneo, Marol, Maxitram sr, Nobligan ret, Oldaram, Qdolo, Rybix odt, Ryzolt, Tilodol sr, Tradorec xl, Tramacet, Tramadol hydrochloride, Tramake, Tramake insts, Tramquel sr, Tramulief sr, Ul...
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Q22.396
Q22
What is Opsumit?
Opsumit, also known generically as Macitentan, was approved by the FDA in 2010 to treat hypertension and idiopathic and/or familial pulmonary arterial hypertension. It is a small molecule therapy that acts as a(n) antagonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_5056', 'tradeNames_string': 'Opsumit', 'drugName': 'Macitentan', 'drugMolecularType': 'Small molecule', 'drugActionType': 'antagonist', 'drugMechanismOfAction': 'Endothelin receptor, ET-A/ET-B antagonist', 'linkedDiseasesDrug_string': 'Pulmonary Hypertension (MONDO_0005149), Heart Failure ...
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Q22.45
Q22
What is Otezla?
Otezla, also known generically as Apremilast, was approved by the FDA in 2014 to treat Oral ulcer, immune system disease, psoriasis, psoriatic arthritis, and pustulosis palmaris et plantaris. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_2487', 'tradeNames_string': 'Otezla', 'drugName': 'Apremilast', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Phosphodiesterase 4 inhibitor', 'linkedDiseasesDrug_string': "Psoriasis (EFO_0000676), Rosacea (EFO_1000760), Oral Lichen Planus (...
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Q22.632
Q22
What is Testosterone Cypionate?
The drug Testosterone Cypionate was approved by the FDA in 1978 to treat neoplasm, orchitis, and hypogonadism. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_434', 'tradeNames_string': 'Andro-Cyp, Depandro, Depo-testosterone, Depotest, Testosterone, Testosterone cypionate', 'drugName': 'Testosterone Cypionate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Androgen Receptor agonist', 'linkedDiseas...
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Q22.71
Q22
What is Giazo?
Giazo, also known generically as Balsalazide Disodium, was approved by the FDA in 2000 to treat ulcerative colitis. It is a small molecule therapy that acts as a(n) agonist and inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_1296', 'tradeNames_string': 'Balsalazide disodium, Colazal, Colazide, Giazo', 'drugName': 'Balsalazide Disodium', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Peroxisome proliferator-activated receptor gamma agonist', 'linkedDiseasesDrug_str...
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Q22.522
Q22
What is Nuplazid?
Nuplazid, also known generically as Pimavanserin Tartrate, was approved by the FDA in 2016 to treat Hallucinations, psychosis, and Parkinson disease. It is a small molecule therapy that acts as a(n) inverse agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_5097', 'tradeNames_string': 'Nuplazid', 'drugName': 'Pimavanserin Tartrate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inverse agonist', 'drugMechanismOfAction': 'Serotonin 2a (5-HT2a) receptor inverse agonist', 'linkedDiseasesDrug_string': 'Psychosis (EFO_0005407), Alzheim...
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Q22.661
Q22
What is Izba?
Izba, also known generically as Travoprost, was approved by the FDA in 2001 to treat glaucoma, open-angle glaucoma, and ocular hypertension. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_3870', 'tradeNames_string': 'Izba, Travatan, Travatan z, Travoprost', 'drugName': 'Travoprost', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Prostanoid FP receptor agonist', 'linkedDiseasesDrug_string': 'Exfoliation Syndrome (EFO_0004235), O...
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Q22.253
Q22
What is Tricor?
Tricor, also known generically as Fenofibrate, was approved by the FDA in 1993 to treat Abnormal circulating lipid concentration, Hypercholesterolemia, cardiovascular disease, diabetes mellitus, hypothyroidism, and type 2 diabetes mellitus. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_1497', 'tradeNames_string': 'Antara, Antara (micronized), Fenofibrate, Fenofibrate (micronized), Fenogal, Fenoglide, Lipantil, Lipantil micro 200, Lipantil micro 267, Lipantil micro 67, Lipidil, Lipofen, Supralip 160, Tricor, Tricor (micronized), Triglide', 'drugName': 'Fenofibrate', 'drug...
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Q22.213
Q22
What is Orilissa?
Orilissa, also known generically as Elagolix Sodium, was approved by the FDA in 2018 to treat endometriosis. It is a small molecule therapy that acts as a(n) antagonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_5526', 'tradeNames_string': 'Orilissa', 'drugName': 'Elagolix Sodium', 'drugMolecularType': 'Small molecule', 'drugActionType': 'antagonist', 'drugMechanismOfAction': 'Gonadotropin-releasing hormone receptor antagonist', 'linkedDiseasesDrug_string': 'Endometriosis (EFO_0001065)', 'newLinke...
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Q22.168
Q22
What is Tafinlar?
Tafinlar, also known generically as Dabrafenib Mesylate, was approved by the FDA in 2013 to treat cutaneous melanoma, melanoma, metastatic melanoma, thyroid carcinoma, and thyroid cancer. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_441', 'tradeNames_string': 'Tafinlar', 'drugName': 'Dabrafenib Mesylate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Serine/threonine-protein kinase B-raf inhibitor', 'linkedDiseasesDrug_string': 'Erdheim-Chester Disease (EFO_1000926), M...
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Q22.476
Q22
What is Patanase?
Patanase, also known generically as Olopatadine Hydrochloride, was approved by the FDA in 1996 to treat Pruritus, seasonal allergic rhinitis, allergic rhinitis, and allergic conjunctivitis. It is a small molecule therapy that acts as a(n) antagonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_6184', 'tradeNames_string': 'Olopatadine hydrochloride, Pataday, Pataday once daily relief, Pataday twice daily relief, Patanase, Patanol, Pazeo', 'drugName': 'Olopatadine Hydrochloride', 'drugMolecularType': 'Small molecule', 'drugActionType': 'antagonist', 'drugMechanismOfAction': 'Hista...
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Q22.167
Q22
What is Tafinlar?
Tafinlar, also known generically as Dabrafenib, was approved by the FDA in 2013 to treat cancer and neoplasm. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_441', 'tradeNames_string': 'Tafinlar', 'drugName': 'Dabrafenib Mesylate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Serine/threonine-protein kinase B-raf inhibitor', 'linkedDiseasesDrug_string': 'Erdheim-Chester Disease (EFO_1000926), M...
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Q22.514
Q22
What is Pemfexy?
Pemfexy, also known generically as Pemetrexed, was approved by the FDA in 2004 to treat cancer, mesothelioma, neoplasm, malignant pleural mesothelioma, and malignant peritoneal mesothelioma. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4615', 'tradeNames_string': 'Alimta, Pemfexy', 'drugName': 'Pemetrexed', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Dihydrofolate reductase inhibitor', 'linkedDiseasesDrug_string': 'Ovarian Carcinoma (EFO_0001075), Cancer (MONDO_0004992)...
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Q22.329
Q22
What is Kalydeco?
Kalydeco, also known generically as Ivacaftor, was approved by the FDA in 2012 to treat respiratory system disease and cystic fibrosis. It is a small molecule therapy that acts as a(n) positive modulator.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_5639', 'tradeNames_string': 'Kalydeco', 'drugName': 'Ivacaftor', 'drugMolecularType': 'Small molecule', 'drugActionType': 'positive modulator', 'drugMechanismOfAction': 'Cystic fibrosis transmembrane conductance regulator positive modulator', 'linkedDiseasesDrug_string': 'Sinusitis (EFO_00...
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Q22.66
Q22
What is Edarbi?
Edarbi, also known generically as Azilsartan Medoxomil, was approved by the FDA in 2011 to treat cardiovascular disease. It is a small molecule therapy that acts as a(n) antagonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_5498', 'tradeNames_string': 'Edarbi', 'drugName': 'Azilsartan Medoxomil', 'drugMolecularType': 'Small molecule', 'drugActionType': 'antagonist', 'drugMechanismOfAction': 'Type-1 angiotensin II receptor antagonist', 'linkedDiseasesDrug_string': 'Stroke (EFO_0000712), Hypertension (EFO_00005...
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Q22.415
Q22
What is Jornay Pm?
Jornay Pm, also known generically as Methylphenidate Hydrochloride, was approved by the FDA in 1955 to treat attention deficit hyperactivity disorder. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_845', 'tradeNames_string': 'Adhansia xr, Aptensio xr, Concerta, Delmosart, Equasym, Equasym xl, Jornay pm, Matoride xl, Medikinet, Medikinet xl, Metadate cd, Metadate er, Methylin, Methylin er, Methylphenidate hydrochloride, Quillichew er, Quillivant xr, Relexxii, Ritalin, Ritalin la, Rita...
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Q22.50
Q22
What is Aristada Initio Kit?
Aristada Initio Kit, also known generically as Aripiprazole Lauroxil, was approved by the FDA in 2015 to treat autism, Tourette syndrome, bipolar I disorder, major depressive disorder, and schizophrenia. It is a small molecule therapy that acts as a(n) partial agonist and antagonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4679', 'tradeNames_string': 'Aristada, Aristada initio kit', 'drugName': 'Aripiprazole Lauroxil', 'drugMolecularType': 'Small molecule', 'drugActionType': 'partial agonist', 'drugMechanismOfAction': 'Dopamine D2 receptor partial agonist', 'linkedDiseasesDrug_string': 'Autism (EFO_0003758),...
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Q22.121
Q22
What is Epidiolex?
Epidiolex, also known generically as Cannabidiol, was approved by the FDA in 2018 to treat Seizure, epilepsy, hamartoma, Lennox-Gastaut syndrome, and Dravet syndrome. It is a small molecule therapy that acts as a(n) negative allosteric modulator.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4055', 'tradeNames_string': 'Epidiolex', 'drugName': 'Cannabidiol', 'drugMolecularType': 'Small molecule', 'drugActionType': 'negative allosteric modulator', 'drugMechanismOfAction': 'Cannabinoid CB1 receptor negative allosteric modulator', 'linkedDiseasesDrug_string': "Autism (EFO_0003758...
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Q22.195
Q22
What is Korsuva?
Korsuva, also known generically as Difelikefalin, was approved by the FDA in 2021 to treat Pruritus and chronic kidney disease. It is a protein therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4408', 'tradeNames_string': 'Korsuva', 'drugName': 'Difelikefalin', 'drugMolecularType': 'Protein', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Kappa opioid receptor agonist', 'linkedDiseasesDrug_string': 'Chronic Kidney Disease (EFO_0003884), Pruritus (HP_0000989), Osteoarthrit...
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Q22.40
Q22
What is Evekeo Odt?
Evekeo Odt, also known generically as Amphetamine Sulfate, was approved by the FDA in 1960 to treat attention deficit hyperactivity disorder and narcolepsy-cataplexy syndrome. It is a small molecule therapy that acts as a(n) releasing agent.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4795', 'tradeNames_string': 'Amphetamine sulfate, Benzadrine, Evekeo, Evekeo odt', 'drugName': 'Amphetamine Sulfate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'releasing agent', 'drugMechanismOfAction': 'Norepinephrine transporter releasing agent', 'linkedDiseasesDrug_strin...
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Q22.263
Q22
What is Children'S Allegra Allergy?
Children'S Allegra Allergy, also known generically as Fexofenadine Hydrochloride, was approved by the FDA in 1996 to treat seasonal allergic rhinitis, urticaria, allergic rhinitis, and allergic disease. It is a small molecule therapy that acts as a(n) antagonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_1045', 'tradeNames_string': "Allegra, Allegra allergy, Allegra hives, Children's allegra allergy, Children's allegra hives, Children's fexofenadine hydrochloride allergy, Children's fexofenadine hydrochloride hives, Fexofenadine hydrochloride, Fexofenadine hydrochloride allergy, Fexofenadi...
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Q22.428
Q22
What is Myrbetriq?
Myrbetriq, also known generically as Mirabegron, was approved by the FDA in 2012 to treat Urinary incontinence, Polyuria, urgency urinary incontinence, and overactive bladder. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_1178', 'tradeNames_string': 'Betmiga, Myrbetriq, Myrbetriq granules', 'drugName': 'Mirabegron', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Beta-3 adrenergic receptor agonist', 'linkedDiseasesDrug_string': 'Urgency Urinary Incontinence (EFO...
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Q22.7
Q22
What is Tudorza Pressair?
Tudorza Pressair, also known generically as Aclidinium Bromide, was approved by the FDA in 2012 to treat Airway obstruction, chronic obstructive pulmonary disease, emphysema, chronic bronchitis, and asthma. It is a small molecule therapy that acts as a(n) antagonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_6136', 'tradeNames_string': 'Eklira, Tudorza pressair', 'drugName': 'Aclidinium Bromide', 'drugMolecularType': 'Small molecule', 'drugActionType': 'antagonist', 'drugMechanismOfAction': 'Muscarinic acetylcholine receptor M3 antagonist', 'linkedDiseasesDrug_string': 'Asthma (MONDO_0004979),...
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Q22.104
Q22
What is Cycloset?
Cycloset, also known generically as Bromocriptine Mesylate, was approved by the FDA in 1978 to treat adenoma, infertility, hyperprolactinemia, acromegaly, hypogonadism, type 2 diabetes mellitus, and Parkinson disease. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4746', 'tradeNames_string': 'Bromocriptine mesylate, Cycloset, Parlodel', 'drugName': 'Bromocriptine Mesylate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'D2-like dopamine receptor agonist', 'linkedDiseasesDrug_string': 'Hypogonadism (MOND...
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Q22.549
Q22
What is Tiglutik Kit?
Tiglutik Kit, also known generically as Riluzole, was approved by the FDA in 1995 to treat amyotrophic lateral sclerosis. It is a small molecule therapy that acts as a(n) blocker.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_2334', 'tradeNames_string': 'Exservan, Rilutek, Riluzole, Teglutik, Tiglutik kit', 'drugName': 'Riluzole', 'drugMolecularType': 'Small molecule', 'drugActionType': 'blocker', 'drugMechanismOfAction': 'Sodium channel alpha subunit blocker', 'linkedDiseasesDrug_string': 'Alzheimer Disease (M...
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Q22.303
Q22
What is Supprelin La?
Supprelin La, also known generically as Histrelin Acetate, was approved by the FDA in 1991 to treat prostate adenocarcinoma and prostate cancer. It is a protein therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_3420', 'tradeNames_string': 'Supprelin, Supprelin la, Vantas', 'drugName': 'Histrelin Acetate', 'drugMolecularType': 'Protein', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Gonadotropin-releasing hormone receptor agonist', 'linkedDiseasesDrug_string': 'Prostate Cancer (MONDO_0008...
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Q22.401
Q22
What is Anjeso?
Anjeso, also known generically as Meloxicam, was approved by the FDA in 2000 to treat rheumatoid arthritis, juvenile idiopathic arthritis, rheumatic disease, and osteoarthritis. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_988', 'tradeNames_string': 'Anjeso, Meloxicam, Mobic, Qmiiz odt, Vivlodex', 'drugName': 'Meloxicam', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Cyclooxygenase-2 inhibitor', 'linkedDiseasesDrug_string': 'Toothache (EFO_0010072), Rheumatic...
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Q22.508
Q22
What is Votrient?
Votrient, also known generically as Pazopanib, was approved by the FDA in 2009 to treat cancer and neoplasm. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_385', 'tradeNames_string': 'Votrient', 'drugName': 'Pazopanib Hydrochloride', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Fibroblast growth factor receptor 1 inhibitor', 'linkedDiseasesDrug_string': 'Papillary Thyroid Carcinoma (EFO_00006...
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Q22.323
Q22
What is Atrovent Hfa?
Atrovent Hfa, also known generically as Ipratropium Bromide, was approved by the FDA in 1986 to treat Nasal congestion, Airway obstruction, Bronchospasm, atopic eczema, chronic obstructive pulmonary disease, emphysema, seasonal allergic rhinitis, chronic bronchitis, common cold, and asthma. It is a small molecule thera...
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4927', 'tradeNames_string': 'Atrovent, Atrovent aerocaps, Atrovent fte, Atrovent hfa, Atrovent udvs, Ipratrop, Ipratrop steripoule, Ipratropium bromide, Respontin, Rinatec, Tropiovent', 'drugName': 'Ipratropium Bromide', 'drugMolecularType': 'Small molecule', 'drugActionType': 'antagonist'...
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Q22.148
Q22
What is Nexiclon Xr?
Nexiclon Xr, also known generically as Clonidine, was approved by the FDA in 1974 to treat cancer, glaucoma, hypertension, attention deficit hyperactivity disorder, neuropathic pain, and migraine disorder. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_615', 'tradeNames_string': 'Catapres, Catapres-tts-1, Catapres-tts-2, Catapres-tts-3, Clonidine, Nexiclon xr', 'drugName': 'Clonidine', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Adrenergic receptor alpha-2 agonist', 'linkedDiseasesDrug_st...
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Q22.493
Q22
What is Opana Er?
Opana Er, also known generically as Oxymorphone Hydrochloride, was approved by the FDA in 1959 to treat pain. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4591', 'tradeNames_string': 'Numorphan, Opana, Opana er, Oxymorphone hydrochloride', 'drugName': 'Oxymorphone Hydrochloride', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Opioid receptors; mu/kappa/delta agonist', 'linkedDiseasesDrug_string'...
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Q22.359
Q22
What is Fetzima?
Fetzima, also known generically as Levomilnacipran, was approved by the FDA in 2013 to treat unipolar depression. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_5567', 'tradeNames_string': 'Fetzima', 'drugName': 'Levomilnacipran Hydrochloride', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Serotonin transporter inhibitor', 'linkedDiseasesDrug_string': 'Fibromyalgia (EFO_0005687), Unipolar Depressio...
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Q22.212
Q22
What is Savaysa?
Savaysa, also known generically as Edoxaban Tosylate, was approved by the FDA in 2015 to treat atrial fibrillation, stroke, pulmonary embolism, and deep vein thrombosis. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_5025', 'tradeNames_string': 'Savaysa', 'drugName': 'Edoxaban Tosylate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Coagulation factor X inhibitor', 'linkedDiseasesDrug_string': 'Stroke (EFO_0000712), Deep Vein Thrombosis (EFO_0003907), V...
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Q22.702
Q22
What is Prialt?
Prialt, also known generically as Ziconotide Acetate, was approved by the FDA in 2004 to treat Fever and pain. It is a protein therapy that acts as a(n) blocker.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_2513', 'tradeNames_string': 'Prialt', 'drugName': 'Ziconotide', 'drugMolecularType': 'Protein', 'drugActionType': 'blocker', 'drugMechanismOfAction': 'Voltage-gated N-type calcium channel alpha-1B subunit blocker', 'linkedDiseasesDrug_string': 'Pain (EFO_0003843), Fever (HP_0001945)', 'new...
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Q22.367
Q22
What is Levothyroxine Sodium?
The drug Levothyroxine Sodium was approved by the FDA in 2000 to treat thyroid carcinoma, hypothyroidism, differentiated thyroid carcinoma, thyroid cancer, and congenital hypothyroidism. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_83', 'tradeNames_string': 'Cytomel, Tertroxin', 'drugName': 'Liothyronine', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Thyroid hormone receptor agonist', 'linkedDiseasesDrug_string': 'Myxedema (EFO_1001055), Multiple Sclerosis (MONDO_00053...
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Q22.89
Q22
What is Angiomax?
Angiomax, also known generically as Bivalirudin, was approved by the FDA in 2000 to treat Thrombocytopenia, Recurrent thrombophlebitis, intermediate coronary syndrome, thrombotic disease, and syndromic disease. It is a protein therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4317', 'tradeNames_string': 'Angiomax, Angiomax rtu, Bivalirudin, Bivalirudin in 0.9% sodium chloride', 'drugName': 'Bivalirudin', 'drugMolecularType': 'Protein', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Thrombin inhibitor', 'linkedDiseasesDrug_string': 'Recurrent Thromboph...
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Q22.671
Q22
What is Trelstar?
Trelstar, also known generically as Triptorelin Pamoate, was approved by the FDA in 2000 to treat prostate adenocarcinoma, prostate carcinoma, Central precocious puberty, and precocious puberty. It is a protein therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4710', 'tradeNames_string': 'Trelstar, Triptodur kit', 'drugName': 'Triptorelin Pamoate', 'drugMolecularType': 'Protein', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Gonadotropin-releasing hormone receptor agonist', 'linkedDiseasesDrug_string': 'Central Precocious Puberty (EFO_0...
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Q22.488
Q22
What is Oxaydo?
Oxaydo, also known generically as Oxycodone Hydrochloride, was approved by the FDA in 1950 to treat Chronic pain and pain. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4049', 'tradeNames_string': 'Abtard, Candox, Carexil, Dolocodon pr, Leveraxo, Longtec, Lynlor, Oxaydo, Oxecta, Oxeltra, Oxycodone hydrochloride, Oxycontin, Oxylan, Oxynorm, Reltebon, Roxicodone, Roxybond, Shortec, Zomestine', 'drugName': 'Oxycodone Hydrochloride', 'drugMolecularType': 'Sma...
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Q22.640
Q22
What is Spiriva?
Spiriva, also known generically as Tiotropium Bromide, was approved by the FDA in 2004 to treat Airway obstruction, Bronchospasm, chronic obstructive pulmonary disease, emphysema, chronic bronchitis, and asthma. It is a small molecule therapy that acts as a(n) antagonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4878', 'tradeNames_string': 'Spiriva, Spiriva respimat', 'drugName': 'Tiotropium Bromide', 'drugMolecularType': 'Small molecule', 'drugActionType': 'antagonist', 'drugMechanismOfAction': 'Muscarinic acetylcholine receptor M3 antagonist', 'linkedDiseasesDrug_string': 'Bronchospasm (HP_00254...
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Q22.42
Q22
What is Erleada?
Erleada, also known generically as Apalutamide, was approved by the FDA in 2018 to treat metastatic prostate cancer, cancer, neoplasm, prostate adenocarcinoma, prostate carcinoma, and prostate cancer. It is a small molecule therapy that acts as a(n) antagonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_6164', 'tradeNames_string': 'Erleada', 'drugName': 'Apalutamide', 'drugMolecularType': 'Small molecule', 'drugActionType': 'antagonist', 'drugMechanismOfAction': 'Androgen Receptor antagonist', 'linkedDiseasesDrug_string': 'Cancer (MONDO_0004992), Prostate Cancer (MONDO_0008315), Neoplasm ...
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Q22.111
Q22
What is Jevtana Kit?
Jevtana Kit, also known generically as Cabazitaxel, was approved by the FDA in 2010 to treat metastatic prostate cancer, cancer, neoplasm, prostate adenocarcinoma, prostate carcinoma, and prostate cancer. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_762', 'tradeNames_string': 'Jevtana, Jevtana kit', 'drugName': 'Cabazitaxel', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Tubulin inhibitor', 'linkedDiseasesDrug_string': 'Cancer (MONDO_0004992), Central Nervous System Cancer (EFO_0000326...
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Q22.697
Q22
What is Voxzogo?
Voxzogo, also known generically as Vosoritide, was approved by the FDA in 2021 to treat bone disease and achondroplasia. It is a protein therapy that acts as a(n) binding agent.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_6124', 'tradeNames_string': 'Voxzogo', 'drugName': 'Vosoritide', 'drugMolecularType': 'Protein', 'drugActionType': 'binding agent', 'drugMechanismOfAction': 'Atrial natriuretic peptide receptor B binding agent', 'linkedDiseasesDrug_string': 'Achondroplasia (MONDO_0007037), Bone Disease (EF...
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Q22.57
Q22
What is Stendra?
Stendra, also known generically as Avanafil, was approved by the FDA in 2011 to treat erectile dysfunction. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_5497', 'tradeNames_string': 'Spedra, Stendra', 'drugName': 'Avanafil', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Phosphodiesterase 5A inhibitor', 'linkedDiseasesDrug_string': 'Kidney Disease (EFO_0003086), Erectile Dysfunction (EFO_0004...
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Q22.430
Q22
What is Pyrukynd?
Pyrukynd, also known generically as Mitapivat Sulfate, was approved by the FDA in 2022 to treat familial hemolytic anemia. It is a small molecule therapy that acts as a(n) activator.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_2811', 'tradeNames_string': 'Pyrukynd', 'drugName': 'Mitapivat Sulfate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'activator', 'drugMechanismOfAction': 'Pyruvate kinase isozymes R/L activator', 'linkedDiseasesDrug_string': 'Familial Hemolytic Anemia (MONDO_0003689)', 'newLi...
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Q22.521
Q22
What is Phenylephrine Hydrochloride?
The drug Phenylephrine Hydrochloride was approved by the FDA in 1952 to treat Pruritus, Nasal congestion, seasonal allergic rhinitis, hypotension, septic shock, common cold, sinusitis, hemorrhoid, and allergic disease. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_3941', 'tradeNames_string': 'Afrin 4 hour nasal spray, Biomydrin, Biorphen, Fenilfar, Fenox, Mydfrin, Nazex, Neo-synephrine, Neosynephrine, Nostril, Nurofen sinus pain relief, Phenylephrine hydrochloride, Prefrin, Vazculep', 'drugName': 'Phenylephrine Hydrochloride', 'drugMolecularType': '...
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Q22.25
Q22
What is Piqray?
Piqray, also known generically as Alpelisib, was approved by the FDA in 2019 to treat breast carcinoma, cancer, neoplasm, breast neoplasm, and breast cancer. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_722', 'tradeNames_string': 'Piqray, Vijoice', 'drugName': 'Alpelisib', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'PI3-kinase p110-alpha subunit inhibitor', 'linkedDiseasesDrug_string': 'Cancer (MONDO_0004992), Multiple Myeloma (EFO_00013...
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Q22.222
Q22
What is Braftovi?
Braftovi, also known generically as Encorafenib, was approved by the FDA in 2018 to treat cancer, cutaneous melanoma, neoplasm, melanoma, and metastatic melanoma. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_3616', 'tradeNames_string': 'Braftovi', 'drugName': 'Encorafenib', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Serine/threonine-protein kinase B-raf inhibitor', 'linkedDiseasesDrug_string': 'Pancreatic Carcinoma (EFO_0002618), Cancer (MON...
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Q22.437
Q22
What is Arymo Er?
Arymo Er, also known generically as Morphine Sulfate, was approved by the FDA in 1984 to treat Chronic pain, cancer, pain, and drug dependence. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_3650', 'tradeNames_string': 'Arymo er, Astramorph pf, Avinza, Depodur, Duramorph, Duramorph pf, Duromorph, Filnarine sr, Infumorph, Kadian, Moraxen, Morcap sr, Morphabond, Morphabond er, Morphgesic sr, Morphine sulfate, Morphine sulfate (autoinjector), Ms contin, Mst continus, Oramorph, Or...
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Q22.285
Q22
What is Givlaari?
Givlaari, also known generically as Givosiran Sodium, was approved by the FDA in 2019 to treat liver disease and Acute hepatic porphyria. It is a oligonucleotide therapy that acts as a(n) rnai inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_5803', 'tradeNames_string': 'Givlaari', 'drugName': 'Givosiran Sodium', 'drugMolecularType': 'Oligonucleotide', 'drugActionType': 'rnai inhibitor', 'drugMechanismOfAction': '5-aminolevulinate synthase mRNA RNAi inhibitor', 'linkedDiseasesDrug_string': 'Acute Hepatic Porphyria (Orphanet_951...
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Q22.113
Q22
What is Cometriq?
Cometriq, also known generically as Cabozantinib, was approved by the FDA in 2012 to treat cancer and neoplasm. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_3579', 'tradeNames_string': 'Cabometyx, Cometriq', 'drugName': 'Cabozantinib S-Malate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Hepatocyte growth factor receptor inhibitor', 'linkedDiseasesDrug_string': 'Ovarian Carcinoma (EFO_0001075...
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Q22.85
Q22
What is Durysta?
Durysta, also known generically as Bimatoprost, was approved by the FDA in 2001 to treat glaucoma, open-angle glaucoma, ocular hypertension, hypotrichosis, and hypotrichosis simplex. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_704', 'tradeNames_string': 'Bimatoprost, Durysta, Latisse, Lumigan', 'drugName': 'Bimatoprost', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Prostanoid FP receptor agonist', 'linkedDiseasesDrug_string': 'Androgenetic Alopecia (EFO_0004191), ...
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Q22.52
Q22
What is Scemblix?
Scemblix, also known generically as Asciminib Hydrochloride, was approved by the FDA in 2021 to treat chronic myelogenous leukemia. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4114', 'tradeNames_string': 'Scemblix', 'drugName': 'Asciminib Hydrochloride', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Bcr/Abl fusion protein inhibitor', 'linkedDiseasesDrug_string': 'Chronic Myelogenous Leukemia (EFO_0000339)', 'newL...
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Q22.224
Q22
What is Xtandi?
Xtandi, also known generically as Enzalutamide, was approved by the FDA in 2012 to treat metastatic prostate cancer, cancer, neoplasm, prostate adenocarcinoma, prostate carcinoma, and prostate cancer. It is a small molecule therapy that acts as a(n) antagonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4352', 'tradeNames_string': 'Xtandi', 'drugName': 'Enzalutamide', 'drugMolecularType': 'Small molecule', 'drugActionType': 'antagonist', 'drugMechanismOfAction': 'Androgen Receptor antagonist', 'linkedDiseasesDrug_string': 'Cancer (MONDO_0004992), Liver Disease (EFO_0001421), Covid-19 (MON...
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Q22.566
Q22
What is Banzel?
Banzel, also known generically as Rufinamide, was approved by the FDA in 2008 to treat Seizure, epilepsy, and Lennox-Gastaut syndrome. It is a small molecule therapy that acts as a(n) blocker.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_5349', 'tradeNames_string': 'Banzel, Inovelon, Rufinamide', 'drugName': 'Rufinamide', 'drugMolecularType': 'Small molecule', 'drugActionType': 'blocker', 'drugMechanismOfAction': 'Sodium channel alpha subunit blocker', 'linkedDiseasesDrug_string': 'Pain (EFO_0003843), Epilepsy (EFO_0000474...
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Q22.551
Q22
What is Adempas?
Adempas, also known generically as Riociguat, was approved by the FDA in 2013 to treat hypertension, pulmonary arterial hypertension, pulmonary hypertension, and idiopathic and/or familial pulmonary arterial hypertension. It is a small molecule therapy that acts as a(n) positive allosteric modulator.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_3991', 'tradeNames_string': 'Adempas, Bay 63-2521', 'drugName': 'Riociguat', 'drugMolecularType': 'Small molecule', 'drugActionType': 'positive allosteric modulator', 'drugMechanismOfAction': 'Soluble guanylate cyclase positive allosteric modulator', 'linkedDiseasesDrug_string': 'Coronary ...
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Q22.306
Q22
What is Zohydro Er?
Zohydro Er, also known generically as Hydrocodone Bitartrate, was approved by the FDA in 1943 to treat pain. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_2476', 'tradeNames_string': 'Dicodid, Hysingla, Hysingla er, Mercodinone, Vantrela er, Zohydro er', 'drugName': 'Hydrocodone Bitartrate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Opioid receptors; mu/kappa/delta agonist', 'linkedDiseases...
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Q22.559
Q22
What is Zoryve?
Zoryve, also known generically as Roflumilast, was approved by the FDA in 2011 to treat Airway obstruction, chronic obstructive pulmonary disease, and chronic bronchitis. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_5055', 'tradeNames_string': 'Daliresp, Daxas, Zoryve', 'drugName': 'Roflumilast', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Phosphodiesterase 4 inhibitor', 'linkedDiseasesDrug_string': 'Psoriasis (EFO_0000676), Cancer (MONDO_0004992), R...
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Q22.219
Q22
What is Epaned?
Epaned, also known generically as Enalapril Maleate, was approved by the FDA in 1985 to treat congestive heart failure, hypertension, and heart failure. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_6274', 'tradeNames_string': 'Ednyt, Enalapril maleate, Enapren, Epaned, Epaned kit, Innovace, Pralenal 10, Pralenal 2.5, Pralenal 20, Pralenal 5, Renitec, Vasotec, Xanef', 'drugName': 'Enalapril Maleate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismO...
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Q22.239
Q22
What is Minivelle?
Minivelle, also known generically as Estradiol, was approved by the FDA in 1975 to treat Premature ovarian insufficiency, Dyspareunia, and hypogonadism. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_6277', 'tradeNames_string': 'Adgyn estro, Alora, Aquagen, Bedol, Climara, Climara Pro, Dermestril 100, Dermestril 25, Dermestril 50, Dermestril septem 25, Dermestril septem 50, Dermestril septem 75, Divigel, E-Cypionate, Elestrim, Elestrin, Elleste solo, Elleste solo mx 40, Elleste solo mx...
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Q22.19
Q22
What is Alecensa?
Alecensa, also known generically as Alectinib, was approved by the FDA in 2015 to treat cancer and neoplasm. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4671', 'tradeNames_string': 'Alecensa', 'drugName': 'Alectinib', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'ALK tyrosine kinase receptor inhibitor', 'linkedDiseasesDrug_string': 'Cancer (MONDO_0004992), Papillary Thyroid Carcinoma (EFO_0...
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Q22.254
Q22
What is Fibricor?
Fibricor, also known generically as Fenofibric Acid, was approved by the FDA in 2008 to treat Hypercholesterolemia and type 2 diabetes mellitus. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_347', 'tradeNames_string': 'Fenocor-67, Fenogal, Fibricor, Lipanthyl, Lipofen, Lofibra, Supralip, Trilipix', 'drugName': 'Fenofibric Acid', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Peroxisome proliferator-activated receptor alpha agonist...
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Q22.264
Q22
What is Children'S Allegra Hives?
Children'S Allegra Hives, also known generically as Fexofenadine Hydrochloride, was approved by the FDA in 1996 to treat seasonal allergic rhinitis, urticaria, allergic rhinitis, and allergic disease. It is a small molecule therapy that acts as a(n) antagonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_1045', 'tradeNames_string': "Allegra, Allegra allergy, Allegra hives, Children's allegra allergy, Children's allegra hives, Children's fexofenadine hydrochloride allergy, Children's fexofenadine hydrochloride hives, Fexofenadine hydrochloride, Fexofenadine hydrochloride allergy, Fexofenadi...
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Q22.436
Q22
What is Singulair?
Singulair, also known generically as Montelukast Sodium, was approved by the FDA in 1998 to treat seasonal allergic rhinitis, allergic rhinitis, Rhinitis, Allergic, Perennial, and asthma. It is a small molecule therapy that acts as a(n) antagonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_2453', 'tradeNames_string': 'Montelukast sodium, Singulair', 'drugName': 'Montelukast Sodium', 'drugMolecularType': 'Small molecule', 'drugActionType': 'antagonist', 'drugMechanismOfAction': 'Cysteinyl leukotriene receptor 1 antagonist', 'linkedDiseasesDrug_string': 'Rhinitis (EFO_0008521)...
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Q22.268
Q22
What is Oforta?
Oforta, also known generically as Fludarabine Phosphate, was approved by the FDA in 1991 to treat chronic lymphocytic leukemia, cancer, and neoplasm. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_2916', 'tradeNames_string': 'Fludara, Fludarabine phosphate, Oforta', 'drugName': 'Fludarabine Phosphate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'DNA polymerase (alpha/delta/epsilon) inhibitor', 'linkedDiseasesDrug_string': "Ovarian ...
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Q22.62
Q22
What is Astepro?
Astepro, also known generically as Azelastine Hydrochloride, was approved by the FDA in 1996 to treat Nasal congestion, seasonal allergic rhinitis, allergic rhinitis, allergic conjunctivitis, vasomotor rhinitis, and Rhinitis, Allergic, Perennial. It is a small molecule therapy that acts as a(n) antagonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_3567', 'tradeNames_string': "Astelin, Astepro, Astepro allergy, Azelastine hydrochloride, Children's astepro allergy, Optilast, Optivar, Rhinolast, Rhinolast allergy", 'drugName': 'Azelastine Hydrochloride', 'drugMolecularType': 'Small molecule', 'drugActionType': 'antagonist', 'drugMechan...
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Q22.217
Q22
What is Viberzi?
Viberzi, also known generically as Eluxadoline, was approved by the FDA in 2015 to treat irritable bowel syndrome. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_6255', 'tradeNames_string': 'Truberzi, Viberzi', 'drugName': 'Eluxadoline', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Mu opioid receptor agonist', 'linkedDiseasesDrug_string': 'Irritable Bowel Syndrome (EFO_0000555)', 'newLinkedTargets_st...
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Q22.383
Q22
What is Loreev Xr?
Loreev Xr, also known generically as Lorazepam, was approved by the FDA in 1977 to treat unipolar depression, anxiety, anxiety disorder, status epilepticus, and depressive disorder. It is a small molecule therapy that acts as a(n) positive allosteric modulator.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_3142', 'tradeNames_string': 'Abbloraz, Ativan, Loraz, Lorazepam, Lorazepam intensol, Lorazepam preservative free, Loreev xr, Temesta', 'drugName': 'Lorazepam', 'drugMolecularType': 'Small molecule', 'drugActionType': 'positive allosteric modulator', 'drugMechanismOfAction': 'GABA-A recepto...
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Q22.30
Q22
What is Letairis?
Letairis, also known generically as Ambrisentan, was approved by the FDA in 2007 to treat hypertension, pulmonary arterial hypertension, pulmonary hypertension, and idiopathic and/or familial pulmonary arterial hypertension. It is a small molecule therapy that acts as a(n) antagonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_3910', 'tradeNames_string': 'Letairis, Volibris', 'drugName': 'Ambrisentan', 'drugMolecularType': 'Small molecule', 'drugActionType': 'antagonist', 'drugMechanismOfAction': 'Endothelin receptor, ET-A/ET-B antagonist', 'linkedDiseasesDrug_string': 'Asthma (MONDO_0004979), Pulmonary Hyperten...
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Q22.185
Q22
What is Pristiq?
Pristiq, also known generically as Desvenlafaxine Succinate, was approved by the FDA in 2008 to treat unipolar depression and major depressive disorder. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_1437', 'tradeNames_string': 'Desvenlafaxine, Khedezla, Pristiq', 'drugName': 'Desvenlafaxine', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Norepinephrine transporter inhibitor', 'linkedDiseasesDrug_string': 'Unipolar Depression (EFO_00037...
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Q22.310
Q22
What is Makena (Autoinjector)?
Makena (Autoinjector), also known generically as Hydroxyprogesterone Caproate, was approved by the FDA in 1975 to treat premature birth. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4832', 'tradeNames_string': 'Delalutin, Hydroxyprogesterone caproate, Makena, Makena (autoinjector), Makena preservative free, Proluton depot', 'drugName': 'Hydroxyprogesterone Caproate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Progeste...
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Q22.394
Q22
What is Lutathera?
Lutathera, also known generically as Lutetium Dotatate Lu-177, was approved by the FDA in 2018 to treat pancreatic neuroendocrine tumor and neuroendocrine neoplasm. It is a unknown therapy that acts as a(n) binding agent.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_3035', 'tradeNames_string': 'Lutathera', 'drugName': 'Lutetium Dotatate Lu-177', 'drugMolecularType': 'Unknown', 'drugActionType': 'binding agent', 'drugMechanismOfAction': 'Somatostatin receptor binding agent', 'linkedDiseasesDrug_string': 'Neuroendocrine Neoplasm (EFO_1001901), Neuroblas...
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Q22.335
Q22
What is Lamictal Xr?
Lamictal Xr, also known generically as Lamotrigine, was approved by the FDA in 1994 to treat Seizure, Bilateral tonic-clonic seizure, bipolar disorder, epilepsy, unipolar depression, partial epilepsy, epilepsy with generalized tonic-clonic seizures, bipolar I disorder, depressive disorder, and Lennox-Gastaut syndrome. ...
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_5462', 'tradeNames_string': 'Lamictal, Lamictal cd, Lamictal odt, Lamictal xr, Lamotrigine', 'drugName': 'Lamotrigine', 'drugMolecularType': 'Small molecule', 'drugActionType': 'blocker', 'drugMechanismOfAction': 'Sodium channel alpha subunit blocker', 'linkedDiseasesDrug_string': 'Periphe...
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Q22.443
Q22
What is Evzio?
Evzio, also known generically as Naloxone Hydrochloride, was approved by the FDA in 1971 to treat unipolar depression, pain, and septic shock. It is a small molecule therapy that acts as a(n) antagonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_3927', 'tradeNames_string': 'Evzio, Evzio (autoinjector), Kloxxado, Nalone, Naloxone, Naloxone hydrochloride, Naloxone hydrochloride (autoinjector), Narcan, Narcan neonatal, Narconil, Prenoxad, Zimhi', 'drugName': 'Naloxone Hydrochloride', 'drugMolecularType': 'Small molecule', 'drugAction...
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Q22.300
Q22
What is Bryhali?
Bryhali, also known generically as Halobetasol Propionate, was approved by the FDA in 1990 to treat psoriasis, skin disease, and psoriasis vulgaris. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_1442', 'tradeNames_string': 'Bryhali, Halobetasol propionate, Lexette, Ultravate', 'drugName': 'Halobetasol Propionate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Glucocorticoid receptor agonist', 'linkedDiseasesDrug_string': 'Psoriasis (...
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Q22.591
Q22
What is Nexavar?
Nexavar, also known generically as Sorafenib Tosylate, was approved by the FDA in 2005 to treat chromophobe renal cell carcinoma, clear cell renal carcinoma, papillary renal cell carcinoma, papillary thyroid carcinoma, renal cell carcinoma, thyroid carcinoma, and thyroid cancer. It is a small molecule therapy that acts...
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_1543', 'tradeNames_string': 'Nexavar', 'drugName': 'Sorafenib Tosylate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Serine/threonine-protein kinase B-raf inhibitor', 'linkedDiseasesDrug_string': 'Cancer (MONDO_0004992), Multiple Myeloma ...
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Q22.348
Q22
What is Eligard Kit?
Eligard Kit, also known generically as Leuprolide Acetate, was approved by the FDA in 1985 to treat metastatic prostate cancer, prostate adenocarcinoma, prostate carcinoma, Central precocious puberty, precocious puberty, prostate cancer, and central precocious puberty. It is a protein therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4802', 'tradeNames_string': 'Carcinil, Eligard, Eligard kit, Fensolvi kit, Leuprolide acetate, Leuprorelin, Lupron, Lupron Depot Ped, Lupron depot, Lupron depot-ped, Lupron depot-ped kit, Lutrate depot kit, Viadur', 'drugName': 'Leuprolide Acetate', 'drugMolecularType': 'Protein', 'drugAct...
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Q22.442
Q22
What is Narcan?
Narcan, also known generically as Naloxone, was approved by the FDA in 1971 to treat Constipation. It is a small molecule therapy that acts as a(n) antagonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_3927', 'tradeNames_string': 'Evzio, Evzio (autoinjector), Kloxxado, Nalone, Naloxone, Naloxone hydrochloride, Naloxone hydrochloride (autoinjector), Narcan, Narcan neonatal, Narconil, Prenoxad, Zimhi', 'drugName': 'Naloxone Hydrochloride', 'drugMolecularType': 'Small molecule', 'drugAction...
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Q22.586
Q22
What is Januvia?
Januvia, also known generically as Sitagliptin Phosphate, was approved by the FDA in 2006 to treat myocardial infarction, stroke, type 2 diabetes mellitus, and hyperlipidemia. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_2411', 'tradeNames_string': 'Janumet Xr, Januvia', 'drugName': 'Sitagliptin Phosphate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Dipeptidyl peptidase IV inhibitor', 'linkedDiseasesDrug_string': 'Diabetes Mellitus (EFO_0000400), Hyperli...
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Q22.332
Q22
What is Ninlaro?
Ninlaro, also known generically as Ixazomib Citrate, was approved by the FDA in 2015 to treat cancer, neoplasm, and multiple myeloma. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_3334', 'tradeNames_string': 'Ninlaro', 'drugName': 'Ixazomib', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': '26S proteasome inhibitor', 'linkedDiseasesDrug_string': 'Cancer (MONDO_0004992), Multiple Myeloma (EFO_0001378), Al Amyloidosis (MO...
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