Datasets:

uuid
stringlengths
4
8
template_uuid
stringclasses
40 values
question
stringlengths
13
193
answer
stringlengths
29
2.2k
benchmark_query
stringlengths
133
622
execution_results
stringlengths
2
1.14M
query_type
stringclasses
2 values
sql_category
stringclasses
26 values
bio_category
stringclasses
14 values
Q22.368
Q22
What is Levoxyl?
Levoxyl, also known generically as Levothyroxine Sodium, was approved by the FDA in 2000 to treat thyroid carcinoma, hypothyroidism, differentiated thyroid carcinoma, thyroid cancer, and congenital hypothyroidism. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_5964', 'tradeNames_string': 'Eltroxin, Ermeza, Euthyrox, Evotrox, L-thyroxine henning, Levo-t, Levolet, Levothroid, Levothyroid, Levothyroxine sodium, Levoxine, Levoxyl, Novothyrox, Soloxine, Synthroid, Thyquidity, Thyro-tabs, Thyrol L, Thyroxine, Tirosint, Tirosint-sol, Unithroid', 'drugN...
general
Similarity Search, Select
Metadata
Q22.624
Q22
What is Tepmetko?
Tepmetko, also known generically as Tepotinib Hydrochloride, was approved by the FDA in 2021 to treat non-small cell lung carcinoma. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_1908', 'tradeNames_string': 'Tepmetko', 'drugName': 'Tepotinib Hydrochloride', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Hepatocyte growth factor receptor inhibitor', 'linkedDiseasesDrug_string': 'Non-Small Cell Lung Carcinoma (EFO_0003...
general
Similarity Search, Select
Metadata
Q22.585
Q22
What is Janumet Xr?
Janumet Xr, also known generically as Sitagliptin Phosphate, was approved by the FDA in 2006 to treat myocardial infarction, stroke, type 2 diabetes mellitus, and hyperlipidemia. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_2411', 'tradeNames_string': 'Janumet Xr, Januvia', 'drugName': 'Sitagliptin Phosphate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Dipeptidyl peptidase IV inhibitor', 'linkedDiseasesDrug_string': 'Diabetes Mellitus (EFO_0000400), Hyperli...
general
Similarity Search, Select
Metadata
Q22.235
Q22
What is Esomeprazole Magnesium?
The drug Esomeprazole Magnesium was approved by the FDA in 2001 to treat Esophagitis, rheumatoid arthritis, ankylosing spondylitis, gastroesophageal reflux disease, duodenal ulcer, Zollinger-Ellison Syndrome, gastric ulcer, and osteoarthritis. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4440', 'tradeNames_string': 'Esomeprazole magnesium, Nexium, Nexium 24hr', 'drugName': 'Esomeprazole Magnesium', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Potassium-transporting ATPase inhibitor', 'linkedDiseasesDrug_string': 'Esophagit...
general
Similarity Search, Select
Metadata
Q22.342
Q22
What is Vyzulta?
Vyzulta, also known generically as Latanoprostene Bunod, was approved by the FDA in 2017 to treat glaucoma, open-angle glaucoma, and ocular hypertension. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_2312', 'tradeNames_string': 'Vesneo, Vyzulta', 'drugName': 'Latanoprostene Bunod', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Prostanoid FP receptor agonist', 'linkedDiseasesDrug_string': 'Open-Angle Glaucoma (EFO_0004190), Ocular Hyperten...
general
Similarity Search, Select
Metadata
Q22.662
Q22
What is Travatan Z?
Travatan Z, also known generically as Travoprost, was approved by the FDA in 2001 to treat glaucoma, open-angle glaucoma, and ocular hypertension. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_3870', 'tradeNames_string': 'Izba, Travatan, Travatan z, Travoprost', 'drugName': 'Travoprost', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Prostanoid FP receptor agonist', 'linkedDiseasesDrug_string': 'Exfoliation Syndrome (EFO_0004235), O...
general
Similarity Search, Select
Metadata
Q22.166
Q22
What is Pradaxa?
Pradaxa, also known generically as Dabigatran Etexilate Mesylate, was approved by the FDA in 2010 to treat atrial fibrillation, stroke, and deep vein thrombosis. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_2486', 'tradeNames_string': 'Pradaxa', 'drugName': 'Dabigatran', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Thrombin inhibitor', 'linkedDiseasesDrug_string': 'Hematoma (EFO_0010680), Ischemic Stroke (HP_0002140), Respiratory Syncytial Vi...
general
Similarity Search, Select
Metadata
Q22.290
Q22
What is Cuvposa?
Cuvposa, also known generically as Glycopyrrolate, was approved by the FDA in 1961 to treat Airway obstruction and gastrointestinal disease. It is a small molecule therapy that acts as a(n) antagonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_1138', 'tradeNames_string': 'Cuvposa, Dartisla odt, Glycopyrrolate, Glyrx-pf, Lonhala magnair kit, Robinul, Robinul forte, Robinul fte, Seebri, Sialanar', 'drugName': 'Glycopyrrolate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'antagonist', 'drugMechanismOfAction': 'Muscarin...
general
Similarity Search, Select
Metadata
Q22.619
Q22
What is Gattex Kit?
Gattex Kit, also known generically as Teduglutide, was approved by the FDA in 2012 to treat short bowel syndrome and primary short bowel syndrome. It is a protein therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_1614', 'tradeNames_string': 'Gattex kit', 'drugName': 'Teduglutide', 'drugMolecularType': 'Protein', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Glucagon-like peptide 2 receptor agonist', 'linkedDiseasesDrug_string': "Hyperlipidemia (MONDO_0021187), Hiv Infection (EFO_0000764), ...
general
Similarity Search, Select
Metadata
Q22.524
Q22
What is Zypitamag?
Zypitamag, also known generically as Pitavastatin Magnesium, was approved by the FDA in 2017 to treat Abnormal circulating lipid concentration and hyperlipidemia. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_1773', 'tradeNames_string': 'Zypitamag', 'drugName': 'Pitavastatin Magnesium', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'HMG-CoA reductase inhibitor', 'linkedDiseasesDrug_string': 'Abnormal Circulating Lipid Concentration (HP_0003119), ...
general
Similarity Search, Select
Metadata
Q22.470
Q22
What is Bylvay?
Bylvay, also known generically as Odevixibat, was approved by the FDA in 2021 to treat Pruritus and familial intrahepatic cholestasis. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_1281', 'tradeNames_string': 'Bylvay', 'drugName': 'Odevixibat', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Ileal bile acid transporter inhibitor', 'linkedDiseasesDrug_string': 'Biliary Atresia (MONDO_0008867), Biliary Liver Cirrhosis (EF...
general
Similarity Search, Select
Metadata
Q22.281
Q22
What is Horizant?
Horizant, also known generically as Gabapentin Enacarbil, was approved by the FDA in 2011 to treat epilepsy, restless legs syndrome, and neuralgia. It is a small molecule therapy that acts as a(n) modulator.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4133', 'tradeNames_string': 'Horizant', 'drugName': 'Gabapentin Enacarbil', 'drugMolecularType': 'Small molecule', 'drugActionType': 'modulator', 'drugMechanismOfAction': 'Voltage-gated calcium channel modulator', 'linkedDiseasesDrug_string': 'Diabetic Neuropathy (EFO_1000783), Migraine Di...
general
Similarity Search, Select
Metadata
Q22.414
Q22
What is Adhansia Xr?
Adhansia Xr, also known generically as Methylphenidate Hydrochloride, was approved by the FDA in 1955 to treat attention deficit hyperactivity disorder. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_845', 'tradeNames_string': 'Adhansia xr, Aptensio xr, Concerta, Delmosart, Equasym, Equasym xl, Jornay pm, Matoride xl, Medikinet, Medikinet xl, Metadate cd, Metadate er, Methylin, Methylin er, Methylphenidate hydrochloride, Quillichew er, Quillivant xr, Relexxii, Ritalin, Ritalin la, Rita...
general
Similarity Search, Select
Metadata
Q22.107
Q22
What is Xaracoll?
Xaracoll, also known generically as Bupivacaine Hydrochloride, was approved by the FDA in 1972 to treat pain. It is a small molecule therapy that acts as a(n) blocker.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_1687', 'tradeNames_string': 'Bupivac hcl, Bupivacaine hydrochloride, Bupivacaine hydrochloride kit, Bupivacaine hydrochloride preservative free, Marcain, Marcaine, Marcaine hydrochloride, Marcaine hydrochloride preservative free, Sensorcaine, Xaracoll', 'drugName': 'Bupivacaine Hydrochlori...
general
Similarity Search, Select
Metadata
Q22.117
Q22
What is Enstilar?
Enstilar, also known generically as Calcipotriene, was approved by the FDA in 1993 to treat psoriasis and psoriasis vulgaris. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_5049', 'tradeNames_string': 'Calcipotriene, Dovobet, Dovonex, Enstilar, Sorilux, Xamiol', 'drugName': 'Calcipotriene', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Vitamin D receptor agonist', 'linkedDiseasesDrug_string': 'Eczema (HP_0000964...
general
Similarity Search, Select
Metadata
Q22.634
Q22
What is Aveed?
Aveed, also known generically as Testosterone Undecanoate, was approved by the FDA in 2014 to treat neoplasm, Klinefelter's syndrome, orchitis, hypogonadism, and hypogonadotropic hypogonadism. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_939', 'tradeNames_string': 'Andriol, Aveed, Jatenzo, Kyzatrex, Nebido, Restandol, Restandol testocap, Tlando, Undestor', 'drugName': 'Testosterone Undecanoate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Androgen Receptor agonist', 'linked...
general
Similarity Search, Select
Metadata
Q22.552
Q22
What is Qinlock?
Qinlock, also known generically as Ripretinib, was approved by the FDA in 2020 to treat neoplasm and gastrointestinal stromal tumor. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_3036', 'tradeNames_string': 'Qinlock', 'drugName': 'Ripretinib', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Stem cell growth factor receptor inhibitor', 'linkedDiseasesDrug_string': 'Gastrointestinal Stromal Tumor (MONDO_0011719), Neopla...
general
Similarity Search, Select
Metadata
Q22.473
Q22
What is Striverdi Respimat?
Striverdi Respimat, also known generically as Olodaterol, was approved by the FDA in 2014 to treat Airway obstruction. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_5322', 'tradeNames_string': 'Striverdi respimat', 'drugName': 'Olodaterol Hydrochloride', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Beta-2 adrenergic receptor agonist', 'linkedDiseasesDrug_string': 'Chronic Bronchitis (EFO_0006505), Chron...
general
Similarity Search, Select
Metadata
Q22.95
Q22
What is Rexulti?
Rexulti, also known generically as Brexpiprazole, was approved by the FDA in 2015 to treat unipolar depression, psychosis, schizoaffective disorder, major depressive disorder, and schizophrenia. It is a small molecule therapy that acts as a(n) partial agonist and antagonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_6348', 'tradeNames_string': 'Rexulti', 'drugName': 'Brexpiprazole', 'drugMolecularType': 'Small molecule', 'drugActionType': 'partial agonist', 'drugMechanismOfAction': 'Serotonin 1a (5-HT1a) receptor partial agonist', 'linkedDiseasesDrug_string': 'Psychosis (EFO_0005407), Post-Traumatic S...
general
Similarity Search, Select
Metadata
Q22.8
Q22
What is Differin?
Differin, also known generically as Adapalene, was approved by the FDA in 1996 to treat acne. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_1916', 'tradeNames_string': 'Adapalene, Differin', 'drugName': 'Adapalene', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Retinoic acid receptor agonist', 'linkedDiseasesDrug_string': 'Skin Disease (EFO_0000701), Acne (EFO_0003894)', 'newLink...
general
Similarity Search, Select
Metadata
Q22.92
Q22
What is Bosulif?
Bosulif, also known generically as Bosutinib, was approved by the FDA in 2010 to treat chronic myelogenous leukemia and neoplasm. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_3955', 'tradeNames_string': 'Bosulif', 'drugName': 'Bosutinib', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Bcr/Abl fusion protein', 'linkedDiseasesDrug_string': 'Blast Phase Chronic Myelogenous Leukemia, Bcr-Abl1 Positive (EFO_1000131), ...
general
Similarity Search, Select
Metadata
Q22.535
Q22
What is Flo-Pred?
Flo-Pred, also known generically as Prednisolone Acetate, was approved by the FDA in 1955 to treat Corneal scarring, Nasal congestion, inflammation, eye inflammation, allergic conjunctivitis, hemorrhoid, anemia, and multiple sclerosis. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_5344', 'tradeNames_string': 'Econopred, Flo-pred, Meticortelone, Omnipred, Pred forte, Pred fte, Pred mild, Prednisolone acetate, Sterane, Ultracortenol', 'drugName': 'Prednisolone Acetate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Gluco...
general
Similarity Search, Select
Metadata
Q22.386
Q22
What is Inveltys?
Inveltys, also known generically as Loteprednol Etabonate, was approved by the FDA in 1998 to treat inflammation, eye inflammation, allergic conjunctivitis, anterior uveitis, and dry eye syndrome. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_5556', 'tradeNames_string': 'Airex, Alrex, Eysuvis, Inveltys, Lotemax, Lotemax sm', 'drugName': 'Loteprednol Etabonate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Glucocorticoid receptor agonist', 'linkedDiseasesDrug_string': 'Allergic Co...
general
Similarity Search, Select
Metadata
Q22.528
Q22
What is Pomalyst?
Pomalyst, also known generically as Pomalidomide, was approved by the FDA in 2013 to treat immune system disease and multiple myeloma. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4886', 'tradeNames_string': 'Imnovid, Pomalyst', 'drugName': 'Pomalidomide', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'CRL4(CRBN) E3 ubiquitin ligase inhibitor', 'linkedDiseasesDrug_string': "Asymptomatic Myeloma (EFO_0003073), Multiple...
general
Similarity Search, Select
Metadata
Q22.546
Q22
What is Rebetol?
Rebetol, also known generically as Ribavirin, was approved by the FDA in 1985 to treat viral disease, cirrhosis of liver, chronic hepatitis C virus infection, and fibrosis. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_3809', 'tradeNames_string': 'Copegus, Rebetol, Ribapak, Ribasphere, Ribavarin, Ribavirin, Ribofluranosyl Carboxamide, Tribavirin, Viramid, Virazid, Virazole', 'drugName': 'Ribavirin', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': "Inosine-5'...
general
Similarity Search, Select
Metadata
Q22.369
Q22
What is Thyquidity?
Thyquidity, also known generically as Levothyroxine Sodium, was approved by the FDA in 2000 to treat thyroid carcinoma, hypothyroidism, differentiated thyroid carcinoma, thyroid cancer, and congenital hypothyroidism. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_5964', 'tradeNames_string': 'Eltroxin, Ermeza, Euthyrox, Evotrox, L-thyroxine henning, Levo-t, Levolet, Levothroid, Levothyroid, Levothyroxine sodium, Levoxine, Levoxyl, Novothyrox, Soloxine, Synthroid, Thyquidity, Thyro-tabs, Thyrol L, Thyroxine, Tirosint, Tirosint-sol, Unithroid', 'drugN...
general
Similarity Search, Select
Metadata
Q22.645
Q22
What is Fotivda?
Fotivda, also known generically as Tivozanib, was approved by the FDA in 2021 to treat neoplasm. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_2104', 'tradeNames_string': 'Fotivda', 'drugName': 'Tivozanib Hydrochloride', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Vascular endothelial growth factor receptor inhibitor', 'linkedDiseasesDrug_string': 'Renal Cell Carcinoma (EFO_0000...
general
Similarity Search, Select
Metadata
Q22.143
Q22
What is Cleviprex?
Cleviprex, also known generically as Clevidipine, was approved by the FDA in 2008 to treat cardiovascular disease. It is a small molecule therapy that acts as a(n) blocker.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_250', 'tradeNames_string': 'Cleviprex', 'drugName': 'Clevidipine', 'drugMolecularType': 'Small molecule', 'drugActionType': 'blocker', 'drugMechanismOfAction': 'Voltage-gated L-type calcium channel blocker', 'linkedDiseasesDrug_string': 'Malignant Hypertension (EFO_1001031), Stroke (EFO_00...
general
Similarity Search, Select
Metadata
Q22.29
Q22
What is Osmolex Er?
Osmolex Er, also known generically as Amantadine Hydrochloride, was approved by the FDA in 1968 to treat Parkinsonism, infection, influenza, cerebral atherosclerosis, secondary Parkinson disease, postencephalitic Parkinson disease, and Parkinson disease. It is a small molecule therapy that acts as a(n) antagonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_768', 'tradeNames_string': 'Amantadine hydrochloride, Gocovri, Lysovir, Mantadine, Osmolex er, Symadine, Symmetrel', 'drugName': 'Amantadine Hydrochloride', 'drugMolecularType': 'Small molecule', 'drugActionType': 'antagonist', 'drugMechanismOfAction': 'Glutamate [NMDA] receptor antagonist...
general
Similarity Search, Select
Metadata
Q22.44
Q22
What is Kynmobi?
Kynmobi, also known generically as Apomorphine Hydrochloride, was approved by the FDA in 2004 to treat Parkinson disease. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_3300', 'tradeNames_string': 'Apo-go, Apo-go pen, Apo-go pfs, Apokyn, Apomorph hcl, Britaject, Bromophin, Dacepton, Diagesil, Diamorph hcl, Diamorph roche, Diamorph,cocaine,chlorpromazine, Diaphine, Euphorin, Kynmobi, Uprima', 'drugName': 'Apomorphine Hydrochloride', 'drugMolecularType': 'S...
general
Similarity Search, Select
Metadata
Q22.43
Q22
What is Eliquis?
Eliquis, also known generically as Apixaban, was approved by the FDA in 2012 to treat Recurrent thrombophlebitis, Venous thrombosis, atrial fibrillation, stroke, pulmonary embolism, deep vein thrombosis, and thrombotic disease. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4326', 'tradeNames_string': 'Eliquis', 'drugName': 'Apixaban', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Coagulation factor X inhibitor', 'linkedDiseasesDrug_string': 'Cancer (MONDO_0004992), Hemorrhage (MP_0001914), Covid-19 (MONDO_010...
general
Similarity Search, Select
Metadata
Q22.74
Q22
What is Qvar 40?
Qvar 40, also known generically as Beclomethasone Dipropionate, was approved by the FDA in 1976 to treat Nasal congestion, Airway obstruction, seasonal allergic rhinitis, allergic rhinitis, Rhinitis, Allergic, Perennial, and asthma. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_5013', 'tradeNames_string': 'Aerobec 100, Aerobec 50, Aerobec fte 250, Asmabec clickhaler, Asmabec spacehaler, Beclazone 100, Beclazone 100 e-breathe, Beclazone 200, Beclazone 250, Beclazone 250 e-breathe, Beclazone 50, Beclazone 50 e-breathe, Becloaqua 50, Becloforte, Becloforte e-breathe...
general
Similarity Search, Select
Metadata
Q22.170
Q22
What is Ryanodex?
Ryanodex, also known generically as Dantrolene Sodium, was approved by the FDA in 1974 to treat Spasticity, Fever, stroke, cerebral palsy, Spinal cord injury, and multiple sclerosis. It is a small molecule therapy that acts as a(n) antagonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4504', 'tradeNames_string': 'Dantrium, Dantrolene sodium, Revonto, Ryanodex', 'drugName': 'Dantrolene Sodium', 'drugMolecularType': 'Small molecule', 'drugActionType': 'antagonist', 'drugMechanismOfAction': 'Ryanodine receptor 3 antagonist', 'linkedDiseasesDrug_string': 'Drug Toxicity (EFO...
general
Similarity Search, Select
Metadata
Q22.214
Q22
What is Cerdelga?
Cerdelga, also known generically as Eliglustat Tartrate, was approved by the FDA in 2014 to treat Gaucher disease. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4249', 'tradeNames_string': 'Cerdelga', 'drugName': 'Eliglustat', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Ceramide glucosyltransferase inhibitor', 'linkedDiseasesDrug_string': 'Gaucher Disease (MONDO_0018150), Gaucher Disease Type 3 (...
general
Similarity Search, Select
Metadata
Q22.617
Q22
What is Fabior?
Fabior, also known generically as Tazarotene, was approved by the FDA in 1997 to treat psoriasis, acne, psoriasis vulgaris, lentigo, and Genetic hypopigmentation of the skin. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_5124', 'tradeNames_string': 'Arazlo, Avage, Fabior, Tazorac, Zorac', 'drugName': 'Tazarotene', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Retinoic acid receptor agonist', 'linkedDiseasesDrug_string': 'Psoriasis (EFO_0000676), Genetic Hypop...
general
Similarity Search, Select
Metadata
Q22.67
Q22
What is Fleqsuvy?
Fleqsuvy, also known generically as Baclofen, was approved by the FDA in 1977 to treat Spasticity, Rigidity, spinal cord disease, cerebral palsy, Spinal cord injury, multiple sclerosis, and brain injury. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_3627', 'tradeNames_string': 'Baclofen, Baclospas-10, Fleqsuvy, Gablofen, Kemstro, Lioresal, Lioresal intrath, Lyflex, Lyvispah, Ozobax', 'drugName': 'Baclofen', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'GABA-B receptor agonist', 'linkedDi...
general
Similarity Search, Select
Metadata
Q22.12
Q22
What is Proair Hfa?
Proair Hfa, also known generically as Albuterol, was approved by the FDA in 1981 to treat Airway obstruction, Bronchospasm, chronic obstructive pulmonary disease, and asthma. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_1434', 'tradeNames_string': 'Aerolin, Aerolin 400, Aerolin auto, Airomir, Airsalb, Albuterol, Asmasal clickhaler, Asmasal spacehaler, Asmaven, Asmavent, Cobutolin, Combivent, Combivent udvs, Ipramol steri-neb, Kentamol, Libetist, Maxivent, Proair Hfa, Proventil, Proventil Hfa, Rimasal, Sal...
general
Similarity Search, Select
Metadata
Q22.666
Q22
What is Tyvaso?
Tyvaso, also known generically as Treprostinil, was approved by the FDA in 2002 to treat Recurrent thrombophlebitis, pulmonary arterial hypertension, and pulmonary hypertension. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_1758', 'tradeNames_string': 'Remodulin, Tyvaso, Tyvaso dpi', 'drugName': 'Treprostinil', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Prostanoid IP receptor agonist', 'linkedDiseasesDrug_string': 'Recurrent Thrombophlebitis (HP_0004419), Pul...
general
Similarity Search, Select
Metadata
Q22.574
Q22
What is Xpovio?
Xpovio, also known generically as Selinexor, was approved by the FDA in 2019 to treat cancer, diffuse large B-cell lymphoma, neoplasm, and multiple myeloma. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_58', 'tradeNames_string': 'Xpovio', 'drugName': 'Selinexor', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Exportin-1 inhibitor', 'linkedDiseasesDrug_string': 'Ovarian Carcinoma (EFO_0001075), Cancer (MONDO_0004992), Multiple Myeloma (EFO_0...
general
Similarity Search, Select
Metadata
Q22.181
Q22
What is Noctiva?
Noctiva, also known generically as Desmopressin Acetate, was approved by the FDA in 1978 to treat Central diabetes insipidus, Nasal congestion, hemorrhage, head injury, diabetes insipidus, enuresis, and von Willebrand disease (hereditary or acquired). It is a protein therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_2993', 'tradeNames_string': 'Concentraid, Ddavp, Ddavp (needs no refrigeration), Desmomelt, Desmopressin acetate, Desmopressin acetate (needs no refrigeration), Desmopressin acetate preservative free, Desmospray, Desmotabs, Minirin, Nocdurna, Noctiva, Nocutil, Noqdirna, Octim, Octostim, Pr...
general
Similarity Search, Select
Metadata
Q22.540
Q22
What is Aspruzyo Sprinkle?
Aspruzyo Sprinkle, also known generically as Ranolazine, was approved by the FDA in 2006 to treat cardiovascular disease and angina pectoris. It is a small molecule therapy that acts as a(n) blocker.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_6340', 'tradeNames_string': 'Aspruzyo sprinkle, Ranexa, Ranolazine', 'drugName': 'Ranolazine', 'drugMolecularType': 'Small molecule', 'drugActionType': 'blocker', 'drugMechanismOfAction': 'Sodium channel protein type IV alpha subunit blocker', 'linkedDiseasesDrug_string': "Prolonged Qt Int...
general
Similarity Search, Select
Metadata
Q22.363
Q22
What is Mirena?
Mirena, also known generically as Levonorgestrel, was approved by the FDA in 1982 to treat Menorrhagia. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_2857', 'tradeNames_string': 'Athentia next, Emerres, Emerres una, Ezinelle, Fallback solo, Her style, Isteranda, Jadelle, Jaydess, Kyleena, Levonelle, Levonelle one step, Levonelle-2, Levonorgestrel, Levosert, Liletta, Microval, Mirena, Norgeston, Norplant, Norplant Ii, Norplant System, Op...
general
Similarity Search, Select
Metadata
Q22.655
Q22
What is Soaanz?
Soaanz, also known generically as Torsemide, was approved by the FDA in 1993 to treat cardiovascular disease, congestive heart failure, hypertension, myocardial infarction, stroke, and heart failure. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4709', 'tradeNames_string': 'Demadex, Soaanz, Torem 10, Torem 2.5, Torem 5, Torsemide', 'drugName': 'Torsemide', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Sodium-(potassium)-chloride cotransporter 2 inhibitor', 'linkedDiseasesDrug_strin...
general
Similarity Search, Select
Metadata
Q22.295
Q22
What is Zoladex?
Zoladex, also known generically as Goserelin Acetate, was approved by the FDA in 1989 to treat breast carcinoma, carcinoma, and breast cancer. It is a protein therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_246', 'tradeNames_string': 'Novgos, Zoladex, Zoladex la', 'drugName': 'Goserelin Acetate', 'drugMolecularType': 'Protein', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Gonadotropin-releasing hormone receptor agonist', 'linkedDiseasesDrug_string': 'Prostate Cancer (MONDO_0008315),...
general
Similarity Search, Select
Metadata
Q22.426
Q22
What is Savella?
Savella, also known generically as Milnacipran Hydrochloride, was approved by the FDA in 2009 to treat fibromyalgia. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4225', 'tradeNames_string': 'Dalcipran, Ixel, Milnacipran hydrochloride, Savella, Toledomin', 'drugName': 'Milnacipran Hydrochloride', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Norepinephrine transporter inhibitor', 'linkedDiseasesDrug_...
general
Similarity Search, Select
Metadata
Q22.180
Q22
What is Nocdurna?
Nocdurna, also known generically as Desmopressin Acetate, was approved by the FDA in 1978 to treat Central diabetes insipidus, Nasal congestion, hemorrhage, head injury, diabetes insipidus, enuresis, and von Willebrand disease (hereditary or acquired). It is a protein therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_2993', 'tradeNames_string': 'Concentraid, Ddavp, Ddavp (needs no refrigeration), Desmomelt, Desmopressin acetate, Desmopressin acetate (needs no refrigeration), Desmopressin acetate preservative free, Desmospray, Desmotabs, Minirin, Nocdurna, Noctiva, Nocutil, Noqdirna, Octim, Octostim, Pr...
general
Similarity Search, Select
Metadata
Q22.462
Q22
What is Genosyl?
Genosyl, also known generically as Nitric Oxide, was approved by the FDA in 1999 to treat Respiratory insufficiency, respiratory system disease, pulmonary arterial hypertension, respiratory failure, and pulmonary hypertension. It is a small molecule therapy that acts as a(n) activator.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_2884', 'tradeNames_string': 'Genosyl, Inomax', 'drugName': 'Nitric Oxide', 'drugMolecularType': 'Small molecule', 'drugActionType': 'activator', 'drugMechanismOfAction': 'Soluble guanylate cyclase activator', 'linkedDiseasesDrug_string': 'Cancer (MONDO_0004992), Infection (EFO_0000544), Pu...
general
Similarity Search, Select
Metadata
Q22.450
Q22
What is Ilevro?
Ilevro, also known generically as Nepafenac, was approved by the FDA in 2005 to treat inflammation, eye inflammation, and cataract. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_5261', 'tradeNames_string': 'Ilevro, Nepafenac, Nevanac', 'drugName': 'Nepafenac', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Cyclooxygenase inhibitor', 'linkedDiseasesDrug_string': 'Cataract (MONDO_0005129), Eye Inflammation (EFO_000575...
general
Similarity Search, Select
Metadata
Q22.86
Q22
What is Latisse?
Latisse, also known generically as Bimatoprost, was approved by the FDA in 2001 to treat glaucoma, open-angle glaucoma, ocular hypertension, hypotrichosis, and hypotrichosis simplex. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_704', 'tradeNames_string': 'Bimatoprost, Durysta, Latisse, Lumigan', 'drugName': 'Bimatoprost', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Prostanoid FP receptor agonist', 'linkedDiseasesDrug_string': 'Androgenetic Alopecia (EFO_0004191), ...
general
Similarity Search, Select
Metadata
Q22.459
Q22
What is Ofev?
Ofev, also known generically as Nintedanib Esylate, was approved by the FDA in 2014 to treat systemic scleroderma and idiopathic pulmonary fibrosis. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_5928', 'tradeNames_string': 'Ofev, Vargatef', 'drugName': 'Nintedanib', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Fibroblast growth factor receptor inhibitor', 'linkedDiseasesDrug_string': 'Genital Neoplasm, Female (EFO_1001331), Multip...
general
Similarity Search, Select
Metadata
Q22.360
Q22
What is Fetzima?
Fetzima, also known generically as Levomilnacipran Hydrochloride, was approved by the FDA in 2013 to treat unipolar depression, fibromyalgia, and major depressive disorder. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_5567', 'tradeNames_string': 'Fetzima', 'drugName': 'Levomilnacipran Hydrochloride', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Serotonin transporter inhibitor', 'linkedDiseasesDrug_string': 'Fibromyalgia (EFO_0005687), Unipolar Depressio...
general
Similarity Search, Select
Metadata
Q22.502
Q22
What is Farydak?
Farydak, also known generically as Panobinostat, was approved by the FDA in 2015 to treat cancer and neoplasm. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4906', 'tradeNames_string': 'Farydak', 'drugName': 'Panobinostat', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Histone deacetylase inhibitor', 'linkedDiseasesDrug_string': 'Cancer (MONDO_0004992), Multiple Myeloma (EFO_0001378), Primary M...
general
Similarity Search, Select
Metadata
Q22.582
Q22
What is Mayzent?
Mayzent, also known generically as Siponimod Fumarate, was approved by the FDA in 2019 to treat chronic progressive multiple sclerosis, relapsing-remitting multiple sclerosis, and multiple sclerosis. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4451', 'tradeNames_string': 'Mayzent', 'drugName': 'Siponimod Fumarate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Sphingosine 1-phosphate receptor Edg-1 agonist', 'linkedDiseasesDrug_string': 'Multiple Sclerosis (MONDO_0005301), Relapsin...
general
Similarity Search, Select
Metadata
Q22.81
Q22
What is Bepreve?
Bepreve, also known generically as Bepotastine Besylate, was approved by the FDA in 2009 to treat Pruritus and allergic conjunctivitis. It is a small molecule therapy that acts as a(n) antagonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_3215', 'tradeNames_string': 'Bepreve', 'drugName': 'Bepotastine Besylate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'antagonist', 'drugMechanismOfAction': 'Histamine H1 receptor antagonist', 'linkedDiseasesDrug_string': 'Allergic Conjunctivitis (EFO_0007141), Rhinitis, Alle...
general
Similarity Search, Select
Metadata
Q22.24
Q22
What is Nesina?
Nesina, also known generically as Alogliptin Benzoate, was approved by the FDA in 2013 to treat type 2 diabetes mellitus. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_2469', 'tradeNames_string': 'Nesina', 'drugName': 'Alogliptin Benzoate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Dipeptidyl peptidase IV inhibitor', 'linkedDiseasesDrug_string': 'Type 2 Diabetes Mellitus (MONDO_0005148)', 'newLinkedTa...
general
Similarity Search, Select
Metadata
Q22.16
Q22
What is Proair Respiclick?
Proair Respiclick, also known generically as Albuterol Sulfate, was approved by the FDA in 1982 to treat Bronchospasm, chronic obstructive pulmonary disease, and asthma. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_6278', 'tradeNames_string': 'Accuneb, Albuterol sulfate, Proair, Proair digihaler, Proair hfa, Proair respiclick, Proventil, Proventil-hfa, Ventolin, Ventolin hfa, Ventolin rotacaps, Volmax, Vospire er', 'drugName': 'Albuterol Sulfate', 'drugMolecularType': 'Small molecule', 'drugActionTyp...
general
Similarity Search, Select
Metadata
Q22.387
Q22
What is Lotemax Sm?
Lotemax Sm, also known generically as Loteprednol Etabonate, was approved by the FDA in 1998 to treat inflammation, eye inflammation, allergic conjunctivitis, anterior uveitis, and dry eye syndrome. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_5556', 'tradeNames_string': 'Airex, Alrex, Eysuvis, Inveltys, Lotemax, Lotemax sm', 'drugName': 'Loteprednol Etabonate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Glucocorticoid receptor agonist', 'linkedDiseasesDrug_string': 'Allergic Co...
general
Similarity Search, Select
Metadata
Q22.296
Q22
What is Sancuso?
Sancuso, also known generically as Granisetron, was approved by the FDA in 1993 to treat Nausea and vomiting, Nausea, cancer, neoplasm, post operative nausea and vomiting, and Chemotherapy-induced nausea and vomiting. It is a small molecule therapy that acts as a(n) antagonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_2107', 'tradeNames_string': 'Kytril, Sancuso, Sustol', 'drugName': 'Granisetron', 'drugMolecularType': 'Small molecule', 'drugActionType': 'antagonist', 'drugMechanismOfAction': 'Serotonin 3a (5-HT3a) receptor antagonist', 'linkedDiseasesDrug_string': 'Cancer (MONDO_0004992), Sepsis (HP_01...
general
Similarity Search, Select
Metadata
Q22.279
Q22
What is Gralise?
Gralise, also known generically as Gabapentin, was approved by the FDA in 1993 to treat Seizure, epilepsy, restless legs syndrome, neuralgia, and postherpetic neuralgia. It is a small molecule therapy that acts as a(n) modulator.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_142', 'tradeNames_string': 'Gabapentin, Gralise, Neurontin', 'drugName': 'Gabapentin', 'drugMolecularType': 'Small molecule', 'drugActionType': 'modulator', 'drugMechanismOfAction': 'Voltage-gated calcium channel modulator', 'linkedDiseasesDrug_string': 'Cancer (MONDO_0004992), Head And Ne...
general
Similarity Search, Select
Metadata
Q22.660
Q22
What is Lysteda?
Lysteda, also known generically as Tranexamic Acid, was approved by the FDA in 1986 to treat Menorrhagia, hemorrhage, and hemophilia A. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_5780', 'tradeNames_string': 'Cyklo-f heavy period relief, Cyklokapron, Exacyl, Lysteda, Menstralite, Tranexamic acid', 'drugName': 'Tranexamic Acid', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Plasminogen inhibitor', 'linkedDiseasesDrug_...
general
Similarity Search, Select
Metadata
Q22.318
Q22
What is Zyclara?
Zyclara, also known generically as Imiquimod, was approved by the FDA in 1997 to treat viral disease, actinic keratosis, basal cell carcinoma, keratosis, and skin basal cell carcinoma. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_1394', 'tradeNames_string': 'Aldara, Imiquimod, Zyclara', 'drugName': 'Imiquimod', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Toll-like receptor 7 agonist', 'linkedDiseasesDrug_string': 'Cancer (MONDO_0004992), Medulloblastoma (EFO_0002939...
general
Similarity Search, Select
Metadata
Q22.526
Q22
What is Trulance?
Trulance, also known generically as Plecanatide, was approved by the FDA in 2017 to treat Constipation. It is a protein therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_5758', 'tradeNames_string': 'Trulance', 'drugName': 'Plecanatide', 'drugMolecularType': 'Protein', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Heat-stable enterotoxin receptor agonist', 'linkedDiseasesDrug_string': 'Constipation (HP_0002019), Irritable Bowel Syndrome (EFO_000055...
general
Similarity Search, Select
Metadata
Q22.140
Q22
What is Sensipar?
Sensipar, also known generically as Cinacalcet, was approved by the FDA in 2004 to treat parathyroid disease. It is a small molecule therapy that acts as a(n) positive allosteric modulator.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_841', 'tradeNames_string': 'Mimpara, Sensipar', 'drugName': 'Cinacalcet Hydrochloride', 'drugMolecularType': 'Small molecule', 'drugActionType': 'positive allosteric modulator', 'drugMechanismOfAction': 'Calcium sensing receptor positive allosteric modulator', 'linkedDiseasesDrug_string': ...
general
Similarity Search, Select
Metadata
Q22.492
Q22
What is Upneeq?
Upneeq, also known generically as Oxymetazoline Hydrochloride, was approved by the FDA in 1986 to treat Nasal congestion, seasonal allergic rhinitis, allergic rhinitis, common cold, sinusitis, rosacea, and ptosis. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_543', 'tradeNames_string': 'Afrazine, Ocuclear, Rhofade, Upneeq, Visine, Visine l.r.', 'drugName': 'Oxymetazoline Hydrochloride', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Adrenergic receptor alpha agonist', 'linkedDiseasesDrug_string': '...
general
Similarity Search, Select
Metadata
Q22.490
Q22
What is Roxybond?
Roxybond, also known generically as Oxycodone Hydrochloride, was approved by the FDA in 1950 to treat Chronic pain and pain. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4049', 'tradeNames_string': 'Abtard, Candox, Carexil, Dolocodon pr, Leveraxo, Longtec, Lynlor, Oxaydo, Oxecta, Oxeltra, Oxycodone hydrochloride, Oxycontin, Oxylan, Oxynorm, Reltebon, Roxicodone, Roxybond, Shortec, Zomestine', 'drugName': 'Oxycodone Hydrochloride', 'drugMolecularType': 'Sma...
general
Similarity Search, Select
Metadata
Q22.34
Q22
What is Katerzia?
Katerzia, also known generically as Amlodipine Benzoate, was approved by the FDA in 2019 to treat diabetes mellitus, hypertension, myocardial infarction, stroke, coronary artery disease, and heart failure. It is a small molecule therapy that acts as a(n) blocker.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_5167', 'tradeNames_string': 'Katerzia', 'drugName': 'Amlodipine Benzoate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'blocker', 'drugMechanismOfAction': 'Voltage-gated L-type calcium channel blocker', 'linkedDiseasesDrug_string': 'Diabetes Mellitus (EFO_0000400), Coronary Ar...
general
Similarity Search, Select
Metadata
Q22.669
Q22
What is Aklief?
Aklief, also known generically as Trifarotene, was approved by the FDA in 2019 to treat acne. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4733', 'tradeNames_string': 'Aklief', 'drugName': 'Trifarotene', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Retinoic acid receptor gamma agonist', 'linkedDiseasesDrug_string': 'Lamellar Ichthyosis (MONDO_0017778), Acne (EFO_0003894), Lymph...
general
Similarity Search, Select
Metadata
Q22.261
Q22
What is Onsolis?
Onsolis, also known generically as Fentanyl Citrate, was approved by the FDA in 1968 to treat cancer and pain. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_733', 'tradeNames_string': 'Abstral, Actiq, Fentanyl, Fentanyl citrate, Fentanyl citrate preservative free, Fentora, Lazanda, Onsolis, Sublimaze, Sublimaze preservative free, Thalamonal', 'drugName': 'Fentanyl Citrate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'd...
general
Similarity Search, Select
Metadata
Q22.10
Q22
What is Gilotrif?
Gilotrif, also known generically as Afatinib, was approved by the FDA in 2013 to treat cancer and neoplasm. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_1042', 'tradeNames_string': 'Gilotrif, Giotrif', 'drugName': 'Afatinib', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Epidermal growth factor receptor erbB1 inhibitor', 'linkedDiseasesDrug_string': 'Cancer (MONDO_0004992), Multiple Myeloma...
general
Similarity Search, Select
Metadata
Q22.23
Q22
What is Tekturna?
Tekturna, also known generically as Aliskiren Fumarate, was approved by the FDA in 2007 to treat hypertension and stroke. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4221', 'tradeNames_string': 'Tekturna', 'drugName': 'Aliskiren Fumarate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Renin inhibitor', 'linkedDiseasesDrug_string': 'Stroke (EFO_0000712), Hypertension (EFO_0000537)', 'newLinkedTargets_str...
general
Similarity Search, Select
Metadata
Q22.550
Q22
What is Nurtec Odt?
Nurtec Odt, also known generically as Rimegepant Sulfate, was approved by the FDA in 2020 to treat migraine disorder. It is a small molecule therapy that acts as a(n) antagonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_3190', 'tradeNames_string': 'Nurtec odt', 'drugName': 'Rimegepant Sulfate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'antagonist', 'drugMechanismOfAction': 'Calcitonin gene-related peptide type 1 receptor antagonist', 'linkedDiseasesDrug_string': 'Migraine Disorder (MONDO_0...
general
Similarity Search, Select
Metadata
Q22.225
Q22
What is Emerphed?
Emerphed, also known generically as Ephedrine Sulfate, was approved by the FDA in 2016 to treat Nasal congestion, seasonal allergic rhinitis, hypotension, common cold, and asthma. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4865', 'tradeNames_string': 'Akovaz, Corphedra, Emerphed, Expansyl, Franol plus, Franol-plus, Isofedrol', 'drugName': 'Ephedrine Sulfate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Adrenergic receptor agonist', 'linkedDiseasesDrug_string'...
general
Similarity Search, Select
Metadata
Q22.410
Q22
What is Riomet Er?
Riomet Er, also known generically as Metformin Hydrochloride, was approved by the FDA in 1995 to treat diabetes mellitus and type 2 diabetes mellitus. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_1887', 'tradeNames_string': 'Bolamyn sr, Diagemet xl, Fortamet, Glucamet 500, Glucamet 850, Glucient sr, Glucophage, Glucophage sr, Glucophage xr, Glumetza, Glyformin, Janumet, Ledermetin, Metabet sr, Metformin hydrochloride, Metsol, Milform, Orabet, Riomet, Riomet er, Sukkarto sr', 'drugN...
general
Similarity Search, Select
Metadata
Q22.691
Q22
What is Viltepso?
Viltepso, also known generically as Viltolarsen, was approved by the FDA in 2020 to treat Duchenne muscular dystrophy and muscular dystrophy. It is a oligonucleotide therapy that acts as a(n) positive modulator.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_2014', 'tradeNames_string': 'Viltepso', 'drugName': 'Viltolarsen', 'drugMolecularType': 'Oligonucleotide', 'drugActionType': 'positive modulator', 'drugMechanismOfAction': 'Dystrophin pre-mRNA positive modulator', 'linkedDiseasesDrug_string': 'Muscular Dystrophy (MONDO_0020121), Duchenne M...
general
Similarity Search, Select
Metadata
Q22.340
Q22
What is Reyvow?
Reyvow, also known generically as Lasmiditan Succinate, was approved by the FDA in 2020 to treat migraine disorder. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_1894', 'tradeNames_string': 'Reyvow', 'drugName': 'Lasmiditan Succinate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Serotonin 1f (5-HT1f) receptor agonist', 'linkedDiseasesDrug_string': 'Migraine Disorder (MONDO_0005277)', 'newLinkedTarge...
general
Similarity Search, Select
Metadata
Q22.87
Q22
What is Lumigan?
Lumigan, also known generically as Bimatoprost, was approved by the FDA in 2001 to treat glaucoma, open-angle glaucoma, ocular hypertension, hypotrichosis, and hypotrichosis simplex. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_704', 'tradeNames_string': 'Bimatoprost, Durysta, Latisse, Lumigan', 'drugName': 'Bimatoprost', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Prostanoid FP receptor agonist', 'linkedDiseasesDrug_string': 'Androgenetic Alopecia (EFO_0004191), ...
general
Similarity Search, Select
Metadata
Q22.341
Q22
What is Xelpros?
Xelpros, also known generically as Latanoprost, was approved by the FDA in 1996 to treat glaucoma, hypertension, open-angle glaucoma, and ocular hypertension. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_318', 'tradeNames_string': 'Latanoprost, Monopost, Xalatan, Xelpros', 'drugName': 'Latanoprost', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Prostanoid FP receptor agonist', 'linkedDiseasesDrug_string': 'Vitiligo (EFO_0004208), Open-Angle G...
general
Similarity Search, Select
Metadata
Q22.251
Q22
What is Antara (Micronized)?
Antara (Micronized), also known generically as Fenofibrate, was approved by the FDA in 1993 to treat Abnormal circulating lipid concentration, Hypercholesterolemia, cardiovascular disease, diabetes mellitus, hypothyroidism, and type 2 diabetes mellitus. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_1497', 'tradeNames_string': 'Antara, Antara (micronized), Fenofibrate, Fenofibrate (micronized), Fenogal, Fenoglide, Lipantil, Lipantil micro 200, Lipantil micro 267, Lipantil micro 67, Lipidil, Lipofen, Supralip 160, Tricor, Tricor (micronized), Triglide', 'drugName': 'Fenofibrate', 'drug...
general
Similarity Search, Select
Metadata
Q22.589
Q22
What is Odomzo?
Odomzo, also known generically as Sonidegib Phosphate, was approved by the FDA in 2015 to treat basal cell carcinoma. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_3933', 'tradeNames_string': 'Odomzo', 'drugName': 'Sonidegib Phosphate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Smoothened homolog inhibitor', 'linkedDiseasesDrug_string': 'Basal Cell Carcinoma (EFO_0004193)', 'newLinkedTargets_strin...
general
Similarity Search, Select
Metadata
Q22.627
Q22
What is Androgel?
Androgel, also known generically as Testosterone, was approved by the FDA in 1972 to treat Hypogonadotropic hypogonadism, Klinefelter's syndrome, orchitis, hypogonadism, and hypogonadotropic hypogonadism. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_5308', 'tradeNames_string': 'Androderm, Androgel, Androgel 1%, Andropatch, Axiron, Fortesta, Intrinsa, Natesto, Striant, Striant sr, Testim, Testim 1%, Testoderm, Testoderm tts, Testogel, Testopatch, Testopel, Testoral, Testosterone, Tostran, Vogelxo', 'drugName': 'Testosterone', 'drugMole...
general
Similarity Search, Select
Metadata
Q22.206
Q22
What is Multaq?
Multaq, also known generically as Dronedarone Hydrochloride, was approved by the FDA in 2009 to treat atrial fibrillation. It is a small molecule therapy that acts as a(n) blocker.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_3872', 'tradeNames_string': 'Multaq', 'drugName': 'Dronedarone Hydrochloride', 'drugMolecularType': 'Small molecule', 'drugActionType': 'blocker', 'drugMechanismOfAction': 'Voltage-gated L-type calcium channel blocker', 'linkedDiseasesDrug_string': 'Atrial Fibrillation (EFO_0000275)', 'new...
general
Similarity Search, Select
Metadata
Q22.199
Q22
What is Docetaxel?
The drug Docetaxel was approved by the FDA in 1996 to treat breast carcinoma, cancer, neoplasm, non-small cell lung carcinoma, breast neoplasm, and breast cancer. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_1267', 'tradeNames_string': '', 'drugName': 'Docetaxel', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Tubulin inhibitor', 'linkedDiseasesDrug_string': 'Ovarian Carcinoma (EFO_0001075), Multiple Myeloma (EFO_0001378), Malignant Colon Neopla...
general
Similarity Search, Select
Metadata
Q22.667
Q22
What is Tyvaso Dpi?
Tyvaso Dpi, also known generically as Treprostinil, was approved by the FDA in 2002 to treat Recurrent thrombophlebitis, pulmonary arterial hypertension, and pulmonary hypertension. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_1758', 'tradeNames_string': 'Remodulin, Tyvaso, Tyvaso dpi', 'drugName': 'Treprostinil', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Prostanoid IP receptor agonist', 'linkedDiseasesDrug_string': 'Recurrent Thrombophlebitis (HP_0004419), Pul...
general
Similarity Search, Select
Metadata
Q22.333
Q22
What is Acular Ls?
Acular Ls, also known generically as Ketorolac Tromethamine, was approved by the FDA in 1989 to treat Ocular pain, inflammation, pain, and cataract. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_2258', 'tradeNames_string': 'Acular, Acular ls, Acular preservative free, Acuvail, Ketorolac tromethamine, Sprix, Toradol', 'drugName': 'Ketorolac Tromethamine', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Cyclooxygenase inhibitor', 'link...
general
Similarity Search, Select
Metadata
Q22.405
Q22
What is Apriso?
Apriso, also known generically as Mesalamine, was approved by the FDA in 1987 to treat ulcerative colitis and proctitis. It is a small molecule therapy that acts as a(n) agonist and inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_3359', 'tradeNames_string': 'Vaprisol', 'drugName': 'Conivaptan Hydrochloride', 'drugMolecularType': 'Small molecule', 'drugActionType': 'antagonist', 'drugMechanismOfAction': 'Vasopressin V2 receptor antagonist', 'linkedDiseasesDrug_string': 'Liver Disease (EFO_0001421), Heart Failure (EF...
general
Similarity Search, Select
Metadata
Q22.96
Q22
What is Alunbrig?
Alunbrig, also known generically as Brigatinib, was approved by the FDA in 2017 to treat neoplasm and non-small cell lung carcinoma. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_1566', 'tradeNames_string': 'Alunbrig', 'drugName': 'Brigatinib', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'ALK tyrosine kinase receptor inhibitor', 'linkedDiseasesDrug_string': 'Anaplastic Large Cell Lymphoma (EFO_0003032), Non-Small C...
general
Similarity Search, Select
Metadata
Q22.594
Q22
What is Lumakras?
Lumakras, also known generically as Sotorasib, was approved by the FDA in 2021 to treat neoplasm and non-small cell lung carcinoma. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_1834', 'tradeNames_string': 'Lumakras', 'drugName': 'Sotorasib', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'GTPase KRas inhibitor', 'linkedDiseasesDrug_string': 'Pancreatic Carcinoma (EFO_0002618), Lung Adenocarcinoma (EFO_0000571), Lung...
general
Similarity Search, Select
Metadata
Q22.298
Q22
What is Intuniv?
Intuniv, also known generically as Guanfacine, was approved by the FDA in 1986 to treat hypertension. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_5983', 'tradeNames_string': 'Intuniv', 'drugName': 'Guanfacine', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Adrenergic receptor alpha-2 agonist', 'linkedDiseasesDrug_string': 'Post-Traumatic Stress Disorder (EFO_0001358), Alzheimer Disease...
general
Similarity Search, Select
Metadata
Q22.269
Q22
What is Iluvien?
Iluvien, also known generically as Fluocinolone Acetonide, was approved by the FDA in 1963 to treat atopic eczema, psoriasis, skin disease, freckles, infectious disease, eye inflammation, hemorrhoid, seborrheic dermatitis, uveitis, and macular retinal edema. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4767', 'tradeNames_string': 'Capex, Derma-smoothe/fs, Dermotic, Fluocet, Fluocinolone acetonide, Fluonid, Fluotrex, Fs shampoo, Iluvien, Retisert, Synalar, Synalar fte, Synalar-c, Synalar-hp, Synalar-n, Synandone, Yutiq', 'drugName': 'Fluocinolone Acetonide', 'drugMolecularType': 'Small mo...
general
Similarity Search, Select
Metadata
Q22.381
Q22
What is Juxtapid?
Juxtapid, also known generically as Lomitapide Mesylate, was approved by the FDA in 2012 to treat Hypercholesterolemia, familial hypercholesterolemia, and homozygous familial hypercholesterolemia. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_3058', 'tradeNames_string': 'Juxtapid', 'drugName': 'Lomitapide Mesylate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Microsomal triglyceride transfer protein inhibitor', 'linkedDiseasesDrug_string': 'Hyperlipidemia (MONDO_0021187), Homo...
general
Similarity Search, Select
Metadata
Q22.187
Q22
What is Dexilant Solutab?
Dexilant Solutab, also known generically as Dexlansoprazole, was approved by the FDA in 2009 to treat Peptic ulcer, Esophagitis, gastroesophageal reflux disease, duodenal ulcer, and gastric ulcer. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_908', 'tradeNames_string': 'Dexilant, Dexilant solutab, Kapidex', 'drugName': 'Dexlansoprazole', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Potassium-transporting ATPase inhibitor', 'linkedDiseasesDrug_string': "Esophagitis (HP_0100633),...
general
Similarity Search, Select
Metadata
Q22.643
Q22
What is Aggrastat?
Aggrastat, also known generically as Tirofiban Hydrochloride, was approved by the FDA in 1998 to treat myocardial infarction. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_2127', 'tradeNames_string': '', 'drugName': 'Tirofiban', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Integrin alpha-IIb/beta-3 inhibitor', 'linkedDiseasesDrug_string': 'Recurrent Thrombophlebitis (HP_0004419), Coronary Artery Disease (EFO...
general
Similarity Search, Select
Metadata
Q22.519
Q22
What is Suprenza?
Suprenza, also known generically as Phentermine Hydrochloride, was approved by the FDA in 1973 to treat obesity. It is a small molecule therapy that acts as a(n) releasing agent.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_5704', 'tradeNames_string': 'Adipex-p, Fastin, Lomaira, Obestin-30, Oby-trim, Ona-mast, Phentermine hydrochloride, Suprenza, Tora, Wilpo', 'drugName': 'Phentermine Hydrochloride', 'drugMolecularType': 'Small molecule', 'drugActionType': 'releasing agent', 'drugMechanismOfAction': 'Norepine...
general
Similarity Search, Select
Metadata
Q22.156
Q22
What is Mitigare?
Mitigare, also known generically as Colchicine, was approved by the FDA in 1961 to treat gout and familial Mediterranean fever. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4743', 'tradeNames_string': 'Colchicine, Colcrys, Gloperba, Mitigare', 'drugName': 'Colchicine', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Tubulin inhibitor', 'linkedDiseasesDrug_string': "Coronary Artery Disease (EFO_0001645), Non-St E...
general
Similarity Search, Select
Metadata
Q22.76
Q22
What is Qvar Redihaler?
Qvar Redihaler, also known generically as Beclomethasone Dipropionate, was approved by the FDA in 1976 to treat Nasal congestion, Airway obstruction, seasonal allergic rhinitis, allergic rhinitis, Rhinitis, Allergic, Perennial, and asthma. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_5013', 'tradeNames_string': 'Aerobec 100, Aerobec 50, Aerobec fte 250, Asmabec clickhaler, Asmabec spacehaler, Beclazone 100, Beclazone 100 e-breathe, Beclazone 200, Beclazone 250, Beclazone 250 e-breathe, Beclazone 50, Beclazone 50 e-breathe, Becloaqua 50, Becloforte, Becloforte e-breathe...
general
Similarity Search, Select
Metadata
Q22.338
Q22
What is Tykerb?
Tykerb, also known generically as Lapatinib Ditosylate, was approved by the FDA in 2007 to treat breast carcinoma, breast neoplasm, and breast cancer. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_2160', 'tradeNames_string': 'Tykerb', 'drugName': 'Lapatinib Ditosylate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Epidermal growth factor receptor erbB1 inhibitor', 'linkedDiseasesDrug_string': 'Central Nervous System Neoplasm (EFO_10...
general
Similarity Search, Select
Metadata
Q22.69
Q22
What is Ozobax?
Ozobax, also known generically as Baclofen, was approved by the FDA in 1977 to treat Spasticity, Rigidity, spinal cord disease, cerebral palsy, Spinal cord injury, multiple sclerosis, and brain injury. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_3627', 'tradeNames_string': 'Baclofen, Baclospas-10, Fleqsuvy, Gablofen, Kemstro, Lioresal, Lioresal intrath, Lyflex, Lyvispah, Ozobax', 'drugName': 'Baclofen', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'GABA-B receptor agonist', 'linkedDi...
general
Similarity Search, Select
Metadata
Q22.622
Q22
What is Torisel?
Torisel, also known generically as Temsirolimus, was approved by the FDA in 2007 to treat cancer, clear cell renal carcinoma, neoplasm, and renal cell carcinoma. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_5750', 'tradeNames_string': 'Torisel', 'drugName': 'Temsirolimus', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'FK506-binding protein 1A inhibitor', 'linkedDiseasesDrug_string': 'Cancer (MONDO_0004992), Multiple Myeloma (EFO_0001378), Neur...
general
Similarity Search, Select
Metadata
Q22.191
Q22
What is Cambia?
Cambia, also known generically as Diclofenac Potassium, was approved by the FDA in 1993 to treat rheumatoid arthritis, pain, osteoarthritis, and migraine disorder. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_3122', 'tradeNames_string': 'Cambia, Voltaren, Voltaren Ophthalmic, Voltaren Xr, Zorvolex, Zorvolex capsules', 'drugName': 'Diclofenac', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Cyclooxygenase inhibitor', 'linkedDiseasesDrug_string': '...
general
Similarity Search, Select
Metadata
Q22.240
Q22
What is Vagifem?
Vagifem, also known generically as Estradiol, was approved by the FDA in 1975 to treat Premature ovarian insufficiency, Dyspareunia, and hypogonadism. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_6277', 'tradeNames_string': 'Adgyn estro, Alora, Aquagen, Bedol, Climara, Climara Pro, Dermestril 100, Dermestril 25, Dermestril 50, Dermestril septem 25, Dermestril septem 50, Dermestril septem 75, Divigel, E-Cypionate, Elestrim, Elestrin, Elleste solo, Elleste solo mx 40, Elleste solo mx...
general
Similarity Search, Select
Metadata