uuid stringlengths 4 8 | template_uuid stringclasses 40
values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 133 622 | execution_results stringlengths 2 1.14M | query_type stringclasses 2
values | sql_category stringclasses 26
values | bio_category stringclasses 14
values |
|---|---|---|---|---|---|---|---|---|
Q22.91 | Q22 | What is Tracleer? | Tracleer, also known generically as Bosentan, was approved by the FDA in 2001 to treat hypertension, pulmonary arterial hypertension, pulmonary hypertension, and idiopathic and/or familial pulmonary arterial hypertension. It is a small molecule therapy that acts as a(n) antagonist. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_379', 'tradeNames_string': 'Tracleer', 'drugName': 'Bosentan', 'drugMolecularType': 'Small molecule', 'drugActionType': 'antagonist', 'drugMechanismOfAction': 'Endothelin receptor, ET-A/ET-B antagonist', 'linkedDiseasesDrug_string': 'Diabetes Mellitus (EFO_0000400), Eisenmenger Syndrome (E... | general | Similarity Search, Select | Metadata |
Q22.597 | Q22 | What is Tosymra? | Tosymra, also known generically as Sumatriptan, was approved by the FDA in 1992 to treat migraine disorder. It is a small molecule therapy that acts as a(n) agonist. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_6077', 'tradeNames_string': 'Imitrex, Sumatriptan, Tosymra', 'drugName': 'Sumatriptan', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Serotonin 1d (5-HT1d) receptor agonist', 'linkedDiseasesDrug_string': 'Migraine Without Aura (MONDO_0100431)... | general | Similarity Search, Select | Metadata |
Q22.120 | Q22 | What is Kengreal? | Kengreal, also known generically as Cangrelor Tetrasodium, was approved by the FDA in 2015 to treat Recurrent thrombophlebitis and myocardial infarction. It is a small molecule therapy that acts as a(n) antagonist. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_1075', 'tradeNames_string': 'Kengreal', 'drugName': 'Cangrelor Tetrasodium', 'drugMolecularType': 'Small molecule', 'drugActionType': 'antagonist', 'drugMechanismOfAction': 'Purinergic receptor P2Y12 antagonist', 'linkedDiseasesDrug_string': 'Recurrent Thrombophlebitis (HP_0004419), Myocar... | general | Similarity Search, Select | Metadata |
Q22.128 | Q22 | What is Coreg Cr? | Coreg Cr, also known generically as Carvedilol, was approved by the FDA in 1995 to treat cardiovascular disease, congestive heart failure, hypertension, myocardial infarction, and heart failure. It is a small molecule therapy that acts as a(n) antagonist. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_3793', 'tradeNames_string': 'Carvedilol, Coreg, Coreg CR, Eucardic 12.5, Eucardic 25, Eucardic 3.125, Eucardic 6.25', 'drugName': 'Carvedilol', 'drugMolecularType': 'Small molecule', 'drugActionType': 'antagonist', 'drugMechanismOfAction': 'Adrenergic receptor beta antagonist', 'linkedDise... | general | Similarity Search, Select | Metadata |
Q22.578 | Q22 | What is Rybelsus? | Rybelsus, also known generically as Semaglutide, was approved by the FDA in 2017 to treat diabetes mellitus and type 2 diabetes mellitus. It is a protein therapy that acts as a(n) agonist. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_6086', 'tradeNames_string': 'Ozempic, Rybelsus, Wegovy', 'drugName': 'Semaglutide', 'drugMolecularType': 'Protein', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Glucagon-like peptide 1 receptor agonist', 'linkedDiseasesDrug_string': 'Diabetes Mellitus (EFO_0000400), Osteopenia (H... | general | Similarity Search, Select | Metadata |
Q22.242 | Q22 | What is Exondys 51? | Exondys 51, also known generically as Eteplirsen, was approved by the FDA in 2016 to treat Duchenne muscular dystrophy and muscular dystrophy. It is a oligonucleotide therapy that acts as a(n) positive modulator. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_3184', 'tradeNames_string': 'Exondys 51', 'drugName': 'Eteplirsen', 'drugMolecularType': 'Oligonucleotide', 'drugActionType': 'positive modulator', 'drugMechanismOfAction': 'Dystrophin pre-mRNA positive modulator', 'linkedDiseasesDrug_string': 'Muscular Dystrophy (MONDO_0020121), Duchenne ... | general | Similarity Search, Select | Metadata |
Q22.1 | Q22 | What is Tymlos? | Tymlos, also known generically as Abaloparatide, was approved by the FDA in 2017 to treat osteoporosis. It is a protein therapy that acts as a(n) agonist. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_1895', 'tradeNames_string': 'Tymlos', 'drugName': 'Abaloparatide', 'drugMolecularType': 'Protein', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Parathyroid hormone receptor agonist', 'linkedDiseasesDrug_string': 'Osteoporosis (EFO_0003882), Bone Fracture (EFO_0003931), Postmenopa... | general | Similarity Search, Select | Metadata |
Q22.698 | Q22 | What is Oxbryta? | Oxbryta, also known generically as Voxelotor, was approved by the FDA in 2019 to treat sickle cell anemia. It is a small molecule therapy that acts as a(n) positive modulator. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_2318', 'tradeNames_string': 'Oxbryta', 'drugName': 'Voxelotor', 'drugMolecularType': 'Small molecule', 'drugActionType': 'positive modulator', 'drugMechanismOfAction': 'Hemoglobin HbA positive modulator', 'linkedDiseasesDrug_string': 'Acute Lung Injury (EFO_0004610), Liver Disease (EFO_000... | general | Similarity Search, Select | Metadata |
Q22.537 | Q22 | What is Milprosa? | Milprosa, also known generically as Progesterone, was approved by the FDA in 1976 to treat hemorrhage, amenorrhea, and endometrial hyperplasia. It is a small molecule therapy that acts as a(n) agonist. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_4799', 'tradeNames_string': 'Crinone, Cyclogest, Endometrin, Gesterol, Lutigest, Milprosa, Prochieve, Progesta-care, Progestasert, Progesterone, Progestin, Prometrium, Regumate, Serenity for women, Syngestrone, Utrogestan', 'drugName': 'Progesterone', 'drugMolecularType': 'Small molecule',... | general | Similarity Search, Select | Metadata |
Q22.637 | Q22 | What is Tlando? | Tlando, also known generically as Testosterone Undecanoate, was approved by the FDA in 2014 to treat neoplasm, Klinefelter's syndrome, orchitis, hypogonadism, and hypogonadotropic hypogonadism. It is a small molecule therapy that acts as a(n) agonist. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_939', 'tradeNames_string': 'Andriol, Aveed, Jatenzo, Kyzatrex, Nebido, Restandol, Restandol testocap, Tlando, Undestor', 'drugName': 'Testosterone Undecanoate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Androgen Receptor agonist', 'linked... | general | Similarity Search, Select | Metadata |
Q22.615 | Q22 | What is Hetlioz Lq? | Hetlioz Lq, also known generically as Tasimelteon, was approved by the FDA in 2014 to treat sleep-wake disorder, Smith-Magenis syndrome, and Chromosomal anomaly. It is a small molecule therapy that acts as a(n) agonist. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_6185', 'tradeNames_string': 'Hetlioz, Hetlioz lq', 'drugName': 'Tasimelteon', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Melatonin receptor agonist', 'linkedDiseasesDrug_string': 'Circadian Rhythm Sleep Disorder (MONDO_0024361), Chromosoma... | general | Similarity Search, Select | Metadata |
Q22.282 | Q22 | What is Ztalmy? | Ztalmy, also known generically as Ganaxolone, was approved by the FDA in 2022 to treat Seizure, epilepsy, and West syndrome. It is a small molecule therapy that acts as a(n) positive allosteric modulator. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_1369', 'tradeNames_string': 'Ztalmy', 'drugName': 'Ganaxolone', 'drugMolecularType': 'Small molecule', 'drugActionType': 'positive allosteric modulator', 'drugMechanismOfAction': 'GABA-A receptor; anion channel positive allosteric modulator', 'linkedDiseasesDrug_string': 'Post-Traumatic St... | general | Similarity Search, Select | Metadata |
Q22.119 | Q22 | What is Invokana? | Invokana, also known generically as Canagliflozin, was approved by the FDA in 2011 to treat diabetes mellitus and type 2 diabetes mellitus. It is a small molecule therapy that acts as a(n) inhibitor. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_4559', 'tradeNames_string': 'Invokana', 'drugName': 'Canagliflozin', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Sodium/glucose cotransporter 2 inhibitor', 'linkedDiseasesDrug_string': 'Diabetes Mellitus (EFO_0000400), Polycystic Ovary Sy... | general | Similarity Search, Select | Metadata |
Q22.232 | Q22 | What is Lexapro? | Lexapro, also known generically as Escitalopram Oxalate, was approved by the FDA in 2002 to treat unipolar depression, anxiety disorder, generalized anxiety disorder, and major depressive disorder. It is a small molecule therapy that acts as a(n) inhibitor. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_4125', 'tradeNames_string': 'Escitalopram oxalate, Lexapro', 'drugName': 'Escitalopram Oxalate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Serotonin transporter inhibitor', 'linkedDiseasesDrug_string': 'Unipolar Depression (EFO_0003761)... | general | Similarity Search, Select | Metadata |
Q22.704 | Q22 | What is Intermezzo? | Intermezzo, also known generically as Zolpidem Tartrate, was approved by the FDA in 1992 to treat insomnia. It is a small molecule therapy that acts as a(n) positive allosteric modulator. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_5904', 'tradeNames_string': 'Ambien, Ambien cr, Edluar, Intermezzo, Stilnoct, Tovalt odt, Zolpidem tartrate, Zolpimist', 'drugName': 'Zolpidem Tartrate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'positive allosteric modulator', 'drugMechanismOfAction': 'GABA A receptor alph... | general | Similarity Search, Select | Metadata |
Q22.324 | Q22 | What is Onivyde? | Onivyde, also known generically as Irinotecan Hydrochloride, was approved by the FDA in 1996 to treat adenocarcinoma and carcinoma. It is a small molecule therapy that acts as a(n) inhibitor. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_5193', 'tradeNames_string': 'Campto, Camptosar, Irinotecan hydrochloride, Onivyde', 'drugName': 'Irinotecan Hydrochloride', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'DNA topoisomerase I inhibitor', 'linkedDiseasesDrug_string': "Ovarian ... | general | Similarity Search, Select | Metadata |
Q22.278 | Q22 | What is Tavalisse? | Tavalisse, also known generically as Fostamatinib Disodium, was approved by the FDA in 2018 to treat Thrombocytopenia and autoimmune thrombocytopenic purpura. It is a small molecule therapy that acts as a(n) inhibitor. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_4030', 'tradeNames_string': 'Tavalisse', 'drugName': 'Fostamatinib Disodium', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Tyrosine-protein kinase SYK inhibitor', 'linkedDiseasesDrug_string': 'Thrombocytopenia (HP_0001873), Autoimmune Thro... | general | Similarity Search, Select | Metadata |
Q22.699 | Q22 | What is Amvuttra? | Amvuttra, also known generically as Vutrisiran, was approved by the FDA in 2022 to treat familial amyloid neuropathy and polyneuropathy. It is a oligonucleotide therapy that acts as a(n) rnai inhibitor. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_2234', 'tradeNames_string': 'Amvuttra', 'drugName': 'Vutrisiran', 'drugMolecularType': 'Oligonucleotide', 'drugActionType': 'rnai inhibitor', 'drugMechanismOfAction': 'Transthyretin mRNA rnai inhibitor', 'linkedDiseasesDrug_string': 'Familial Amyloid Neuropathy (EFO_0004129), Polyneuropath... | general | Similarity Search, Select | Metadata |
Q22.147 | Q22 | What is Olux E? | Olux E, also known generically as Clobetasol Propionate, was approved by the FDA in 1985 to treat psoriasis, skin disease, and psoriasis vulgaris. It is a small molecule therapy that acts as a(n) agonist. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_5376', 'tradeNames_string': 'Clarelux, Clobaderm, Clobetasol propionate, Clobetasol propionate (emollient), Clobex, Cormax, Dermovate, Dermovate nn, Embeline, Embeline e, Etrivex, Impeklo, Impoyz, Olux, Olux e, Temovate, Temovate e', 'drugName': 'Clobetasol Propionate', 'drugMolecularType'... | general | Similarity Search, Select | Metadata |
Q22.388 | Q22 | What is Adasuve? | Adasuve, also known generically as Loxapine, was approved by the FDA in 1975 to treat Agitation, psychosis, bipolar I disorder, and schizophrenia. It is a small molecule therapy that acts as a(n) antagonist. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_4041', 'tradeNames_string': 'Adasuve, Loxitane intramuscular [as hydrochloride], Loxitane-c oral suspension [as hydrochloride]', 'drugName': 'Loxapine', 'drugMolecularType': 'Small molecule', 'drugActionType': 'antagonist', 'drugMechanismOfAction': 'Serotonin 2a (5-HT2a) receptor antagonis... | general | Similarity Search, Select | Metadata |
Q22.432 | Q22 | What is Provigil? | Provigil, also known generically as Modafinil, was approved by the FDA in 1998 to treat attention deficit hyperactivity disorder. It is a small molecule therapy that acts as a(n) inhibitor. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_5145', 'tradeNames_string': 'Modafinil, Provigil', 'drugName': 'Modafinil', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Dopamine transporter inhibitor', 'linkedDiseasesDrug_string': 'Alzheimer Disease (MONDO_0004975), Orthostatic Hypotens... | general | Similarity Search, Select | Metadata |
Q22.638 | Q22 | What is Thalomid? | Thalomid, also known generically as Thalidomide, was approved by the FDA in 1998 to treat immune system disease and multiple myeloma. It is a small molecule therapy that acts as a(n) inhibitor. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_64', 'tradeNames_string': 'Talidex, Thalomid', 'drugName': 'Thalidomide', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'CRL4(CRBN) E3 ubiquitin ligase inhibitor', 'linkedDiseasesDrug_string': "Psoriasis (EFO_0000676), Multiple Myeloma (EFO_... | general | Similarity Search, Select | Metadata |
Q22.507 | Q22 | What is Onpattro? | Onpattro, also known generically as Patisiran Sodium, was approved by the FDA in 2018 to treat familial amyloid neuropathy, polyneuropathy, and amyloidosis. It is a oligonucleotide therapy that acts as a(n) rnai inhibitor. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_2512', 'tradeNames_string': 'Onpattro', 'drugName': 'Patisiran Sodium', 'drugMolecularType': 'Oligonucleotide', 'drugActionType': 'rnai inhibitor', 'drugMechanismOfAction': 'Transthyretin mRNA RNAi inhibitor', 'linkedDiseasesDrug_string': 'Amyloidosis (EFO_1001875), Familial Amyloid Neurop... | general | Similarity Search, Select | Metadata |
Q22.272 | Q22 | What is Tolak? | Tolak, also known generically as Fluorouracil, was approved by the FDA in 1962 to treat adenocarcinoma, cancer, neoplasm, actinic keratosis, basal cell carcinoma, and keratosis. It is a small molecule therapy that acts as a(n) inhibitor. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_1558', 'tradeNames_string': '5.f.u., Accusite, Actikerall, Adrucil, Carac, Efudex, Efudix, Fluoro-uracil roche, Fluoroplex, Fluorouracil, Tolak', 'drugName': 'Fluorouracil', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Thymidylate synthase... | general | Similarity Search, Select | Metadata |
Q22.471 | Q22 | What is Lynparza? | Lynparza, also known generically as Olaparib, was approved by the FDA in 2014 to treat cancer, neoplasm, ovarian carcinoma, ovarian neoplasm, and ovarian cancer. It is a small molecule therapy that acts as a(n) inhibitor. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_279', 'tradeNames_string': 'Lynparza', 'drugName': 'Olaparib', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'PARP 1, 2 and 3 inhibitor', 'linkedDiseasesDrug_string': 'Ovarian Carcinoma (EFO_0001075), Cancer (MONDO_0004992), Chronic Lymphocy... | general | Similarity Search, Select | Metadata |
Q22.47 | Q22 | What is Emend? | Emend, also known generically as Aprepitant, was approved by the FDA in 2003 to treat Nausea and vomiting, Nausea, cancer, post operative nausea and vomiting, and Chemotherapy-induced nausea and vomiting. It is a small molecule therapy that acts as a(n) antagonist. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_1299', 'tradeNames_string': 'Aprepitant, Cinvanti, Emend', 'drugName': 'Aprepitant', 'drugMolecularType': 'Small molecule', 'drugActionType': 'antagonist', 'drugMechanismOfAction': 'Neurokinin 1 receptor antagonist', 'linkedDiseasesDrug_string': 'Cancer (MONDO_0004992), Multiple Myeloma (E... | general | Similarity Search, Select | Metadata |
Q22.265 | Q22 | What is Kerendia? | Kerendia, also known generically as Finerenone, was approved by the FDA in 2021 to treat cardiovascular disease and chronic kidney disease. It is a small molecule therapy that acts as a(n) antagonist. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_365', 'tradeNames_string': 'Kerendia', 'drugName': 'Finerenone', 'drugMolecularType': 'Small molecule', 'drugActionType': 'antagonist', 'drugMechanismOfAction': 'Mineralocorticoid receptor antagonist', 'linkedDiseasesDrug_string': 'Chronic Kidney Disease (EFO_0003884), Heart Failure (EFO_0... | general | Similarity Search, Select | Metadata |
Q22.198 | Q22 | What is Vumerity? | Vumerity, also known generically as Diroximel Fumarate, was approved by the FDA in 2019 to treat immune system disease and multiple sclerosis. It is a small molecule therapy that acts as a(n) inhibitor. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_5578', 'tradeNames_string': 'Vumerity', 'drugName': 'Diroximel Fumarate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Kelch-like ECH-associated protein 1 inhibitor', 'linkedDiseasesDrug_string': 'Multiple Sclerosis (MONDO_0005301), Relaps... | general | Similarity Search, Select | Metadata |
Q22.705 | Q22 | What is Zolpimist? | Zolpimist, also known generically as Zolpidem Tartrate, was approved by the FDA in 1992 to treat insomnia. It is a small molecule therapy that acts as a(n) positive allosteric modulator. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_5904', 'tradeNames_string': 'Ambien, Ambien cr, Edluar, Intermezzo, Stilnoct, Tovalt odt, Zolpidem tartrate, Zolpimist', 'drugName': 'Zolpidem Tartrate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'positive allosteric modulator', 'drugMechanismOfAction': 'GABA A receptor alph... | general | Similarity Search, Select | Metadata |
Q22.590 | Q22 | What is Nexavar? | Nexavar, also known generically as Sorafenib, was approved by the FDA in 2005 to treat cancer, neoplasm, and renal cell carcinoma. It is a small molecule therapy that acts as a(n) inhibitor. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_1543', 'tradeNames_string': 'Nexavar', 'drugName': 'Sorafenib Tosylate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Serine/threonine-protein kinase B-raf inhibitor', 'linkedDiseasesDrug_string': 'Cancer (MONDO_0004992), Multiple Myeloma ... | general | Similarity Search, Select | Metadata |
Q22.110 | Q22 | What is Forfivo Xl? | Forfivo Xl, also known generically as Bupropion Hydrochloride, was approved by the FDA in 1985 to treat unipolar depression, mood disorder, major depressive disorder, and depressive disorder. It is a small molecule therapy that acts as a(n) inhibitor. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_771', 'tradeNames_string': 'Bupropion hydrochloride, Forfivo xl, Wellbutrin, Wellbutrin 100, Wellbutrin 75, Wellbutrin sr, Wellbutrin xl, Zyban', 'drugName': 'Bupropion Hydrochloride', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Norepinep... | general | Similarity Search, Select | Metadata |
Q22.468 | Q22 | What is Ocaliva? | Ocaliva, also known generically as Obeticholic Acid, was approved by the FDA in 2016 to treat Cholangitis, biliary liver cirrhosis, and primary biliary cirrhosis. It is a small molecule therapy that acts as a(n) agonist. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_3863', 'tradeNames_string': 'Ocaliva', 'drugName': 'Obeticholic Acid', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Bile acid receptor FXR agonist', 'linkedDiseasesDrug_string': "Familial Adenomatous Polyposis (Orphanet_733), Hepatitis, Alco... | general | Similarity Search, Select | Metadata |
Q22.616 | Q22 | What is Arazlo? | Arazlo, also known generically as Tazarotene, was approved by the FDA in 1997 to treat psoriasis, acne, psoriasis vulgaris, lentigo, and Genetic hypopigmentation of the skin. It is a small molecule therapy that acts as a(n) agonist. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_5124', 'tradeNames_string': 'Arazlo, Avage, Fabior, Tazorac, Zorac', 'drugName': 'Tazarotene', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Retinoic acid receptor agonist', 'linkedDiseasesDrug_string': 'Psoriasis (EFO_0000676), Genetic Hypop... | general | Similarity Search, Select | Metadata |
Q22.538 | Q22 | What is Hemangeol? | Hemangeol, also known generically as Propranolol Hydrochloride, was approved by the FDA in 1967 to treat hypertension, stroke, angina pectoris, cardiac arrhythmia, Wolff-Parkinson-White Syndrome, migraine disorder, and coronary atherosclerosis. It is a small molecule therapy that acts as a(n) antagonist. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_4718', 'tradeNames_string': 'Angilol, Apsolol, Avlocardyl, Bedranol, Bedranol s.r., Berkolol, Beta-prograne mr, Betadur cr, Cardinol, Dupromex, Half beta-prograne mr, Half propanix la, Half propatard la, Half-beprane cr, Half-betadur cr, Half-inderal la, Hemangeol, Inderal, Inderal la, Inn... | general | Similarity Search, Select | Metadata |
Q22.103 | Q22 | What is Prolensa? | Prolensa, also known generically as Bromfenac Sodium, was approved by the FDA in 1997 to treat Ocular pain, inflammation, and cataract. It is a small molecule therapy that acts as a(n) inhibitor. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_989', 'tradeNames_string': 'Bromday, Bromfenac sodium, Bromsite, Prolensa, Xibrom', 'drugName': 'Bromfenac Sodium', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Cyclooxygenase inhibitor', 'linkedDiseasesDrug_string': 'Cataract (MONDO_00051... | general | Similarity Search, Select | Metadata |
Q22.356 | Q22 | What is Xyzal Allergy 24Hr? | Xyzal Allergy 24Hr, also known generically as Levocetirizine Dihydrochloride, was approved by the FDA in 2007 to treat Pruritus, seasonal allergic rhinitis, urticaria, allergic conjunctivitis, and Rhinitis, Allergic, Perennial. It is a small molecule therapy that acts as a(n) antagonist. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_5631', 'tradeNames_string': 'Levocetirizine dihydrochloride, Xusal, Xyzal, Xyzal allergy 24hr, Xyzall', 'drugName': 'Levocetirizine Dihydrochloride', 'drugMolecularType': 'Small molecule', 'drugActionType': 'antagonist', 'drugMechanismOfAction': 'Histamine H1 receptor antagonist', 'linkedD... | general | Similarity Search, Select | Metadata |
Q22.631 | Q22 | What is Vogelxo? | Vogelxo, also known generically as Testosterone, was approved by the FDA in 1972 to treat Hypogonadotropic hypogonadism, Klinefelter's syndrome, orchitis, hypogonadism, and hypogonadotropic hypogonadism. It is a small molecule therapy that acts as a(n) agonist. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_5308', 'tradeNames_string': 'Androderm, Androgel, Androgel 1%, Andropatch, Axiron, Fortesta, Intrinsa, Natesto, Striant, Striant sr, Testim, Testim 1%, Testoderm, Testoderm tts, Testogel, Testopatch, Testopel, Testoral, Testosterone, Tostran, Vogelxo', 'drugName': 'Testosterone', 'drugMole... | general | Similarity Search, Select | Metadata |
Q22.339 | Q22 | What is Vitrakvi? | Vitrakvi, also known generically as Larotrectinib Sulfate, was approved by the FDA in 2018 to treat cancer, neoplasm, and metastasis. It is a small molecule therapy that acts as a(n) inhibitor. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_3998', 'tradeNames_string': 'Vitrakvi', 'drugName': 'Larotrectinib Sulfate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Neurotrophic tyrosine kinase receptor inhibitor', 'linkedDiseasesDrug_string': 'Cancer (MONDO_0004992), Metastasis (E... | general | Similarity Search, Select | Metadata |
Q22.182 | Q22 | What is Verdeso? | Verdeso, also known generically as Desonide, was approved by the FDA in 1972 to treat atopic eczema, skin disease, and eye inflammation. It is a small molecule therapy that acts as a(n) agonist. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_1842', 'tradeNames_string': 'Cortalone, Dekotil, Delta-cortef, Deltacortril, Deltalone, Dilacort, Fernisolone-p, Hydeltra, Meti-derm, Meticortelone, Pevanti, Precortisyl, Precortisyl fte, Prednisolone, Prelone, Scheriproct, Servisone, Sterane', 'drugName': 'Prednisolone', 'drugMolecularTyp... | general | Similarity Search, Select | Metadata |
Q22.308 | Q22 | What is Dilaudid? | Dilaudid, also known generically as Hydromorphone Hydrochloride, was approved by the FDA in 1984 to treat pain and drug dependence. It is a small molecule therapy that acts as a(n) agonist. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_3034', 'tradeNames_string': '', 'drugName': 'Hydromorphone', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Mu opioid receptor agonist', 'linkedDiseasesDrug_string': 'Cancer (MONDO_0004992), Opioid Use Disorder (EFO_0010702), Drug Dependence (... | general | Similarity Search, Select | Metadata |
Q22.355 | Q22 | What is Spritam? | Spritam, also known generically as Levetiracetam, was approved by the FDA in 1999 to treat Seizure, Bilateral tonic-clonic seizure, Focal-onset seizure, epilepsy, and epilepsy with generalized tonic-clonic seizures. It is a small molecule therapy that acts as a(n) modulator and blocker. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_283', 'tradeNames_string': 'Desitrend, Elepsia xr, Keppra, Keppra xr, Levetiracetam, Levetiracetam in sodium chloride, Matever, Spritam', 'drugName': 'Levetiracetam', 'drugMolecularType': 'Small molecule', 'drugActionType': 'modulator', 'drugMechanismOfAction': 'Synaptic vesicle glycoprote... | general | Similarity Search, Select | Metadata |
Q22.152 | Q22 | What is Cotellic? | Cotellic, also known generically as Cobimetinib Fumarate, was approved by the FDA in 2015 to treat metastatic melanoma. It is a small molecule therapy that acts as a(n) inhibitor. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_3656', 'tradeNames_string': 'Cotellic', 'drugName': 'Cobimetinib', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Dual specificity mitogen-activated protein kinase kinase 1 inhibitor', 'linkedDiseasesDrug_string': 'Cancer (MONDO_0004992), Mu... | general | Similarity Search, Select | Metadata |
Q22.127 | Q22 | What is Vraylar? | Vraylar, also known generically as Cariprazine Hydrochloride, was approved by the FDA in 2015 to treat bipolar disorder, bipolar I disorder, and schizophrenia. It is a small molecule therapy that acts as a(n) modulator. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_4947', 'tradeNames_string': 'Vraylar', 'drugName': 'Cariprazine Hydrochloride', 'drugMolecularType': 'Small molecule', 'drugActionType': 'modulator', 'drugMechanismOfAction': 'Dopamine D3 receptor modulator', 'linkedDiseasesDrug_string': 'Schizophrenia (MONDO_0005090), Bipolar Disorder (MO... | general | Similarity Search, Select | Metadata |
Q22.558 | Q22 | What is Daliresp? | Daliresp, also known generically as Roflumilast, was approved by the FDA in 2011 to treat Airway obstruction, chronic obstructive pulmonary disease, and chronic bronchitis. It is a small molecule therapy that acts as a(n) inhibitor. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_5055', 'tradeNames_string': 'Daliresp, Daxas, Zoryve', 'drugName': 'Roflumilast', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Phosphodiesterase 4 inhibitor', 'linkedDiseasesDrug_string': 'Psoriasis (EFO_0000676), Cancer (MONDO_0004992), R... | general | Similarity Search, Select | Metadata |
Q22.612 | Q22 | What is Nucynta Er? | Nucynta Er, also known generically as Tapentadol Hydrochloride, was approved by the FDA in 2008 to treat Chronic pain, pain, and neuropathic pain. It is a small molecule therapy that acts as a(n) agonist and inhibitor. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_6372', 'tradeNames_string': 'Nucynta, Nucynta er, Palexia', 'drugName': 'Tapentadol Hydrochloride', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Mu opioid receptor agonist', 'linkedDiseasesDrug_string': 'Pain (EFO_0003843), Chronic Pain (HP_... | general | Similarity Search, Select | Metadata |
Q22.188 | Q22 | What is Xelstrym? | Xelstrym, also known generically as Dextroamphetamine, was approved by the FDA in 1955 to treat obesity, attention deficit hyperactivity disorder, drug dependence, arteriosclerosis disorder, and narcolepsy-cataplexy syndrome. It is a small molecule therapy that acts as a(n) inhibitor and releasing agent. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_5075', 'tradeNames_string': 'Dexedrine, Dextrostat, Xelstrym', 'drugName': 'Dextroamphetamine', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Synaptic vesicular amine transporter inhibitor', 'linkedDiseasesDrug_string': 'Methamphetamine Dep... | general | Similarity Search, Select | Metadata |
Q22.434 | Q22 | What is Bafiertam? | Bafiertam, also known generically as Monomethyl Fumarate, was approved by the FDA in 2020 to treat multiple sclerosis. It is a small molecule therapy that acts as a(n) inhibitor. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_313', 'tradeNames_string': 'Bafiertam', 'drugName': 'Monomethyl Fumarate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Kelch-like ECH-associated protein 1 inhibitor', 'linkedDiseasesDrug_string': 'Multiple Sclerosis (MONDO_0005301), Relap... | general | Similarity Search, Select | Metadata |
Q22.565 | Q22 | What is Rubraca? | Rubraca, also known generically as Rucaparib Camsylate, was approved by the FDA in 2016 to treat ovarian carcinoma and ovarian cancer. It is a small molecule therapy that acts as a(n) inhibitor. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_6042', 'tradeNames_string': 'Rubraca', 'drugName': 'Rucaparib Camsylate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'PARP 1, 2 and 3 inhibitor', 'linkedDiseasesDrug_string': 'Ovarian Carcinoma (EFO_0001075), Ovarian Cancer (MONDO_0008170... | general | Similarity Search, Select | Metadata |
Q22.696 | Q22 | What is Trintellix? | Trintellix, also known generically as Vortioxetine Hydrobromide, was approved by the FDA in 2013 to treat unipolar depression and major depressive disorder. It is a small molecule therapy that acts as a(n) agonist, inhibitor, and antagonist. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_776', 'tradeNames_string': 'Trintellix', 'drugName': 'Vortioxetine Hydrobromide', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Serotonin transporter inhibitor', 'linkedDiseasesDrug_string': 'Unipolar Depression (EFO_0003761), Major Depress... | general | Similarity Search, Select | Metadata |
Q22.350 | Q22 | What is Lupron Depot? | Lupron Depot, also known generically as Leuprolide Acetate, was approved by the FDA in 1985 to treat metastatic prostate cancer, prostate adenocarcinoma, prostate carcinoma, Central precocious puberty, precocious puberty, prostate cancer, and central precocious puberty. It is a protein therapy that acts as a(n) agonist... | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_4802', 'tradeNames_string': 'Carcinil, Eligard, Eligard kit, Fensolvi kit, Leuprolide acetate, Leuprorelin, Lupron, Lupron Depot Ped, Lupron depot, Lupron depot-ped, Lupron depot-ped kit, Lutrate depot kit, Viadur', 'drugName': 'Leuprolide Acetate', 'drugMolecularType': 'Protein', 'drugAct... | general | Similarity Search, Select | Metadata |
Q22.651 | Q22 | What is Qudexy Xr? | Qudexy Xr, also known generically as Topiramate, was approved by the FDA in 1996 to treat Seizure, epilepsy, migraine disorder, and Lennox-Gastaut syndrome. It is a small molecule therapy that acts as a(n) inhibitor, positive modulator, blocker, and antagonist. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_1592', 'tradeNames_string': 'Epitomax, Eprontia, Qudexy xr, Topamax, Topamax sprinkle, Topiramate, Trokendi xr', 'drugName': 'Topiramate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'blocker', 'drugMechanismOfAction': 'Sodium channel alpha subunit blocker', 'linkedDiseasesDru... | general | Similarity Search, Select | Metadata |
Q22.145 | Q22 | What is Clobex? | Clobex, also known generically as Clobetasol Propionate, was approved by the FDA in 1985 to treat psoriasis, skin disease, and psoriasis vulgaris. It is a small molecule therapy that acts as a(n) agonist. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_5376', 'tradeNames_string': 'Clarelux, Clobaderm, Clobetasol propionate, Clobetasol propionate (emollient), Clobex, Cormax, Dermovate, Dermovate nn, Embeline, Embeline e, Etrivex, Impeklo, Impoyz, Olux, Olux e, Temovate, Temovate e', 'drugName': 'Clobetasol Propionate', 'drugMolecularType'... | general | Similarity Search, Select | Metadata |
Q22.144 | Q22 | What is Sympazan? | Sympazan, also known generically as Clobazam, was approved by the FDA in 2005 to treat Seizure, anxiety, and Lennox-Gastaut syndrome. It is a small molecule therapy that acts as a(n) positive allosteric modulator. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_5981', 'tradeNames_string': 'Frisium, Onfi, Perizam, Sympazan, Tapclob, Urbanyl', 'drugName': 'Clobazam', 'drugMolecularType': 'Small molecule', 'drugActionType': 'positive allosteric modulator', 'drugMechanismOfAction': 'GABA-A receptor; anion channel positive allosteric modulator', 'link... | general | Similarity Search, Select | Metadata |
Q22.399 | Q22 | What is Camzyos? | Camzyos, also known generically as Mavacamten, was approved by the FDA in 2022 to treat hypertrophic cardiomyopathy. It is a small molecule therapy that acts as a(n) inhibitor. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_1036', 'tradeNames_string': 'Camzyos', 'drugName': 'Mavacamten', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Cardiac myosin inhibitor', 'linkedDiseasesDrug_string': 'Heart Failure (EFO_0003144), Hypertrophic Cardiomyopathy (EFO_0000538)',... | general | Similarity Search, Select | Metadata |
Q22.325 | Q22 | What is Absorica Ld? | Absorica Ld, also known generically as Isotretinoin, was approved by the FDA in 1982 to treat acne. It is a small molecule therapy that acts as a(n) agonist. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_3116', 'tradeNames_string': 'Absorica, Absorica ld, Accutane, Amnesteem, Claravis, Isotrex, Myorisan, Roaccutane, Sotret, Zenatane', 'drugName': 'Isotretinoin', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Retinoic acid receptor agonist', 'l... | general | Similarity Search, Select | Metadata |
Q22.20 | Q22 | What is Alecensa? | Alecensa, also known generically as Alectinib Hydrochloride, was approved by the FDA in 2015 to treat non-small cell lung carcinoma. It is a small molecule therapy that acts as a(n) inhibitor. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_4671', 'tradeNames_string': 'Alecensa', 'drugName': 'Alectinib', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'ALK tyrosine kinase receptor inhibitor', 'linkedDiseasesDrug_string': 'Cancer (MONDO_0004992), Papillary Thyroid Carcinoma (EFO_0... | general | Similarity Search, Select | Metadata |
Q22.175 | Q22 | What is Zegalogue? | Zegalogue, also known generically as Dasiglucagon Hydrochloride, was approved by the FDA in 2021 to treat Hypoglycemia and type 1 diabetes mellitus. It is a unknown therapy that acts as a(n) agonist. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_4736', 'tradeNames_string': 'Zegalogue, Zegalogue (autoinjector)', 'drugName': 'Dasiglucagon Hydrochloride', 'drugMolecularType': 'Unknown', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Glucagon receptor agonist', 'linkedDiseasesDrug_string': 'Hypoglycemia (HP_0001943), Type 1 Di... | general | Similarity Search, Select | Metadata |
Q22.639 | Q22 | What is Brilinta? | Brilinta, also known generically as Ticagrelor, was approved by the FDA in 2011 to treat Recurrent thrombophlebitis, myocardial infarction, stroke, coronary artery disease, acute coronary syndrome, acute myocardial infarction, thrombotic disease, and type 2 diabetes mellitus. It is a small molecule therapy that acts as... | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_4496', 'tradeNames_string': 'Brilinta, Brilique', 'drugName': 'Ticagrelor', 'drugMolecularType': 'Small molecule', 'drugActionType': 'negative allosteric modulator', 'drugMechanismOfAction': 'Purinergic receptor P2Y12 negative allosteric modulator', 'linkedDiseasesDrug_string': 'Coronary A... | general | Similarity Search, Select | Metadata |
Q22.316 | Q22 | What is Gleevec? | Gleevec, also known generically as Imatinib Mesylate, was approved by the FDA in 2001 to treat chronic myelogenous leukemia. It is a small molecule therapy that acts as a(n) inhibitor. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_2515', 'tradeNames_string': '', 'drugName': 'Imatinib', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Tyrosine-protein kinase ABL inhibitor', 'linkedDiseasesDrug_string': 'Papillary Thyroid Carcinoma (EFO_0000641), Wet Macular Degeneration ... | general | Similarity Search, Select | Metadata |
Q22.657 | Q22 | What is Qdolo? | Qdolo, also known generically as Tramadol Hydrochloride, was approved by the FDA in 1995 to treat Chronic pain, pain, and drug dependence. It is a small molecule therapy that acts as a(n) agonist. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_3268', 'tradeNames_string': 'Aceon, Conzip, Dromadol sr, Dromadol xl, Invodol sr, Larapam sr, Mabron, Maneo, Marol, Maxitram sr, Nobligan ret, Oldaram, Qdolo, Rybix odt, Ryzolt, Tilodol sr, Tradorec xl, Tramacet, Tramadol hydrochloride, Tramake, Tramake insts, Tramquel sr, Tramulief sr, Ul... | general | Similarity Search, Select | Metadata |
Q22.13 | Q22 | What is Ventolin Hfa? | Ventolin Hfa, also known generically as Albuterol, was approved by the FDA in 1981 to treat Airway obstruction, Bronchospasm, chronic obstructive pulmonary disease, and asthma. It is a small molecule therapy that acts as a(n) agonist. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_1434', 'tradeNames_string': 'Aerolin, Aerolin 400, Aerolin auto, Airomir, Airsalb, Albuterol, Asmasal clickhaler, Asmasal spacehaler, Asmaven, Asmavent, Cobutolin, Combivent, Combivent udvs, Ipramol steri-neb, Kentamol, Libetist, Maxivent, Proair Hfa, Proventil, Proventil Hfa, Rimasal, Sal... | general | Similarity Search, Select | Metadata |
Q22.309 | Q22 | What is Dilaudid-Hp? | Dilaudid-Hp, also known generically as Hydromorphone Hydrochloride, was approved by the FDA in 1984 to treat pain and drug dependence. It is a small molecule therapy that acts as a(n) agonist. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_3034', 'tradeNames_string': '', 'drugName': 'Hydromorphone', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Mu opioid receptor agonist', 'linkedDiseasesDrug_string': 'Cancer (MONDO_0004992), Opioid Use Disorder (EFO_0010702), Drug Dependence (... | general | Similarity Search, Select | Metadata |
Q22.26 | Q22 | What is Vijoice? | Vijoice, also known generically as Alpelisib, was approved by the FDA in 2019 to treat breast carcinoma, cancer, neoplasm, breast neoplasm, and breast cancer. It is a small molecule therapy that acts as a(n) inhibitor. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_722', 'tradeNames_string': 'Piqray, Vijoice', 'drugName': 'Alpelisib', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'PI3-kinase p110-alpha subunit inhibitor', 'linkedDiseasesDrug_string': 'Cancer (MONDO_0004992), Multiple Myeloma (EFO_00013... | general | Similarity Search, Select | Metadata |
Q22.525 | Q22 | What is Wakix? | Wakix, also known generically as Pitolisant Hydrochloride, was approved by the FDA in 2019 to treat hypersomnia and narcolepsy-cataplexy syndrome. It is a small molecule therapy that acts as a(n) inverse agonist. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_1748', 'tradeNames_string': 'Wakix, Wakix, europe', 'drugName': 'Pitolisant', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inverse agonist', 'drugMechanismOfAction': 'Histamine H3 receptor inverse agonist', 'linkedDiseasesDrug_string': 'Idiopathic Hypersomnia (MONDO_0018044), ... | general | Similarity Search, Select | Metadata |
Q22.172 | Q22 | What is Quviviq? | Quviviq, also known generically as Daridorexant Hydrochloride, was approved by the FDA in 2022 to treat insomnia. It is a small molecule therapy that acts as a(n) antagonist. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_5696', 'tradeNames_string': 'Quviviq', 'drugName': 'Daridorexant Hydrochloride', 'drugMolecularType': 'Small molecule', 'drugActionType': 'antagonist', 'drugMechanismOfAction': 'Orexin receptor 2 antagonist', 'linkedDiseasesDrug_string': 'Insomnia (EFO_0004698)', 'newLinkedTargets_string':... | general | Similarity Search, Select | Metadata |
Q22.486 | Q22 | What is Oxycontin? | Oxycontin, also known generically as Oxycodone, was approved by the FDA in 1950 to treat Chronic pain, pain, drug dependence, and substance abuse. It is a small molecule therapy that acts as a(n) agonist. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_6046', 'tradeNames_string': 'Oxycontin, Proladone, Xtampza er', 'drugName': 'Oxycodone', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Mu opioid receptor agonist', 'linkedDiseasesDrug_string': 'Toothache (EFO_0010072), Cancer (MONDO_0004992),... | general | Similarity Search, Select | Metadata |
Q22.417 | Q22 | What is Quillichew Er? | Quillichew Er, also known generically as Methylphenidate Hydrochloride, was approved by the FDA in 1955 to treat attention deficit hyperactivity disorder. It is a small molecule therapy that acts as a(n) inhibitor. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_845', 'tradeNames_string': 'Adhansia xr, Aptensio xr, Concerta, Delmosart, Equasym, Equasym xl, Jornay pm, Matoride xl, Medikinet, Medikinet xl, Metadate cd, Metadate er, Methylin, Methylin er, Methylphenidate hydrochloride, Quillichew er, Quillivant xr, Relexxii, Ritalin, Ritalin la, Rita... | general | Similarity Search, Select | Metadata |
Q22.249 | Q22 | What is Inrebic? | Inrebic, also known generically as Fedratinib Hydrochloride, was approved by the FDA in 2019 to treat Myelofibrosis and primary myelofibrosis. It is a small molecule therapy that acts as a(n) inhibitor. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_4654', 'tradeNames_string': 'Inrebic', 'drugName': 'Fedratinib Hydrochloride', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Tyrosine-protein kinase JAK2 inhibitor', 'linkedDiseasesDrug_string': 'Myelofibrosis (HP_0011974), Primary Myelofib... | general | Similarity Search, Select | Metadata |
Q22.302 | Q22 | What is Ultravate? | Ultravate, also known generically as Halobetasol Propionate, was approved by the FDA in 1990 to treat psoriasis, skin disease, and psoriasis vulgaris. It is a small molecule therapy that acts as a(n) agonist. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_1442', 'tradeNames_string': 'Bryhali, Halobetasol propionate, Lexette, Ultravate', 'drugName': 'Halobetasol Propionate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Glucocorticoid receptor agonist', 'linkedDiseasesDrug_string': 'Psoriasis (... | general | Similarity Search, Select | Metadata |
Q22.440 | Q22 | What is Symproic? | Symproic, also known generically as Naldemedine Tosylate, was approved by the FDA in 2017 to treat Constipation, pain, and constipation disorder. It is a small molecule therapy that acts as a(n) antagonist. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_1003', 'tradeNames_string': 'Symproic', 'drugName': 'Naldemedine Tosylate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'antagonist', 'drugMechanismOfAction': 'Mu opioid receptor antagonist', 'linkedDiseasesDrug_string': 'Constipation (HP_0002019), Constipation Disorder (MONDO... | general | Similarity Search, Select | Metadata |
Q22.276 | Q22 | What is Emend? | Emend, also known generically as Fosaprepitant Dimeglumine, was approved by the FDA in 2008 to treat Nausea and vomiting, cancer, post operative nausea and vomiting, and Chemotherapy-induced nausea and vomiting. It is a small molecule therapy that acts as a(n) antagonist. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_1299', 'tradeNames_string': 'Aprepitant, Cinvanti, Emend', 'drugName': 'Aprepitant', 'drugMolecularType': 'Small molecule', 'drugActionType': 'antagonist', 'drugMechanismOfAction': 'Neurokinin 1 receptor antagonist', 'linkedDiseasesDrug_string': 'Cancer (MONDO_0004992), Multiple Myeloma (E... | general | Similarity Search, Select | Metadata |
Q22.157 | Q22 | What is Aliqopa? | Aliqopa, also known generically as Copanlisib Hydrochloride, was approved by the FDA in 2017 to treat neoplasm of mature B-cells and follicular lymphoma. It is a small molecule therapy that acts as a(n) inhibitor. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_1213', 'tradeNames_string': 'Aliqopa', 'drugName': 'Copanlisib Hydrochloride', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'PI3-kinase p110-delta subunit inhibitor', 'linkedDiseasesDrug_string': 'Multiple Myeloma (EFO_0001378), Follicular ... | general | Similarity Search, Select | Metadata |
Q22.129 | Q22 | What is Coreg Cr? | Coreg Cr, also known generically as Carvedilol Phosphate, was approved by the FDA in 2006 to treat hypertension and myocardial infarction. It is a small molecule therapy that acts as a(n) antagonist. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_3793', 'tradeNames_string': 'Carvedilol, Coreg, Coreg CR, Eucardic 12.5, Eucardic 25, Eucardic 3.125, Eucardic 6.25', 'drugName': 'Carvedilol', 'drugMolecularType': 'Small molecule', 'drugActionType': 'antagonist', 'drugMechanismOfAction': 'Adrenergic receptor beta antagonist', 'linkedDise... | general | Similarity Search, Select | Metadata |
Q22.545 | Q22 | What is Yupelri? | Yupelri, also known generically as Revefenacin, was approved by the FDA in 2018 to treat Airway obstruction and chronic obstructive pulmonary disease. It is a small molecule therapy that acts as a(n) antagonist. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_4223', 'tradeNames_string': 'Yupelri', 'drugName': 'Revefenacin', 'drugMolecularType': 'Small molecule', 'drugActionType': 'antagonist', 'drugMechanismOfAction': 'Muscarinic acetylcholine receptor M3 antagonist', 'linkedDiseasesDrug_string': 'Airway Obstruction (HP_0006536), Liver Disease ... | general | Similarity Search, Select | Metadata |
Q22.347 | Q22 | What is Zurampic? | Zurampic, also known generically as Lesinurad, was approved by the FDA in 2015 to treat gout and hyperuricemia. It is a small molecule therapy that acts as a(n) inhibitor. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_1001', 'tradeNames_string': 'Zurampic', 'drugName': 'Lesinurad', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Solute carrier family 22 member 12 inhibitor', 'linkedDiseasesDrug_string': 'Gout (EFO_0004274), Hyperuricemia (EFO_0009104)', 'n... | general | Similarity Search, Select | Metadata |
Q22.291 | Q22 | What is Lonhala Magnair Kit? | Lonhala Magnair Kit, also known generically as Glycopyrrolate, was approved by the FDA in 1961 to treat Airway obstruction and gastrointestinal disease. It is a small molecule therapy that acts as a(n) antagonist. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_1138', 'tradeNames_string': 'Cuvposa, Dartisla odt, Glycopyrrolate, Glyrx-pf, Lonhala magnair kit, Robinul, Robinul forte, Robinul fte, Seebri, Sialanar', 'drugName': 'Glycopyrrolate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'antagonist', 'drugMechanismOfAction': 'Muscarin... | general | Similarity Search, Select | Metadata |
Q22.116 | Q22 | What is Rayaldee? | Rayaldee, also known generically as Calcifediol, was approved by the FDA in 1980 to treat chronic kidney disease, parathyroid disease, and secondary hyperparathyroidism. It is a small molecule therapy that acts as a(n) agonist. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_6195', 'tradeNames_string': 'Calderol, Rayaldee', 'drugName': 'Calcifediol', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Vitamin D receptor agonist', 'linkedDiseasesDrug_string': 'Chronic Kidney Disease (EFO_0003884), Secondary Hyperparathy... | general | Similarity Search, Select | Metadata |
Q22.373 | Q22 | What is Zingo? | Zingo, also known generically as Lidocaine Hydrochloride, was approved by the FDA in 1948 to treat Back pain, prostate carcinoma, and pain. It is a small molecule therapy that acts as a(n) blocker. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_4126', 'tradeNames_string': 'Akten, Alphacaine hydrochloride, Anestacon, Anodesyn, Bismodyne, Bradosol plus, Calgel, Co-phenylcaine fte, Denela, Dequaspray, Emla, Germoloids, Germoloids complete, Glydo, Hemocane, Iglu, Instillagel, Laryng-o-jet kit, Laryngojet, Laryngotracheal anesthesia k... | general | Similarity Search, Select | Metadata |
Q22.176 | Q22 | What is Zegalogue (Autoinjector)? | Zegalogue (Autoinjector), also known generically as Dasiglucagon Hydrochloride, was approved by the FDA in 2021 to treat Hypoglycemia and type 1 diabetes mellitus. It is a unknown therapy that acts as a(n) agonist. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_4736', 'tradeNames_string': 'Zegalogue, Zegalogue (autoinjector)', 'drugName': 'Dasiglucagon Hydrochloride', 'drugMolecularType': 'Unknown', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Glucagon receptor agonist', 'linkedDiseasesDrug_string': 'Hypoglycemia (HP_0001943), Type 1 Di... | general | Similarity Search, Select | Metadata |
Q22.361 | Q22 | What is Kyleena? | Kyleena, also known generically as Levonorgestrel, was approved by the FDA in 1982 to treat Menorrhagia. It is a small molecule therapy that acts as a(n) agonist. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_2857', 'tradeNames_string': 'Athentia next, Emerres, Emerres una, Ezinelle, Fallback solo, Her style, Isteranda, Jadelle, Jaydess, Kyleena, Levonelle, Levonelle one step, Levonelle-2, Levonorgestrel, Levosert, Liletta, Microval, Mirena, Norgeston, Norplant, Norplant Ii, Norplant System, Op... | general | Similarity Search, Select | Metadata |
Q22.58 | Q22 | What is Ayvakit? | Ayvakit, also known generically as Avapritinib, was approved by the FDA in 2020 to treat cancer, neoplasm, and gastrointestinal stromal tumor. It is a small molecule therapy that acts as a(n) inhibitor. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_3139', 'tradeNames_string': 'Ayvakit', 'drugName': 'Avapritinib', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Stem cell growth factor receptor inhibitor', 'linkedDiseasesDrug_string': 'Cancer (MONDO_0004992), Neoplasm (EFO_0000616), Gastr... | general | Similarity Search, Select | Metadata |
Q22.449 | Q22 | What is Vivitrol? | Vivitrol, also known generically as Naltrexone, was approved by the FDA in 1984 to treat alcohol abuse and alcohol dependence. It is a small molecule therapy that acts as a(n) antagonist. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_3607', 'tradeNames_string': 'Celupan, Trexal, Trexan, Vivitrol', 'drugName': 'Naltrexone', 'drugMolecularType': 'Small molecule', 'drugActionType': 'antagonist', 'drugMechanismOfAction': 'Opioid receptors; mu/kappa/delta antagonist', 'linkedDiseasesDrug_string': "Psoriasis (EFO_0000676), M... | general | Similarity Search, Select | Metadata |
Q22.226 | Q22 | What is Veletri? | Veletri, also known generically as Epoprostenol Sodium, was approved by the FDA in 1995 to treat pulmonary arterial hypertension. It is a small molecule therapy that acts as a(n) agonist. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_1500', 'tradeNames_string': 'Epoprostenol sodium, Flolan, Veletri', 'drugName': 'Epoprostenol Sodium', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Prostanoid IP receptor agonist', 'linkedDiseasesDrug_string': 'Pulmonary Arterial Hypertensio... | general | Similarity Search, Select | Metadata |
Q22.284 | Q22 | What is Xospata? | Xospata, also known generically as Gilteritinib Fumarate, was approved by the FDA in 2018 to treat acute myeloid leukemia and myeloid leukemia. It is a small molecule therapy that acts as a(n) inhibitor. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_3307', 'tradeNames_string': 'Xospata', 'drugName': 'Gilteritinib Fumarate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Tyrosine-protein kinase receptor FLT3 inhibitor', 'linkedDiseasesDrug_string': 'Acute Myeloid Leukemia (EFO_0000222), ... | general | Similarity Search, Select | Metadata |
Q22.18 | Q22 | What is Lastacaft? | Lastacaft, also known generically as Alcaftadine, was approved by the FDA in 2010 to treat eye allergy and allergic conjunctivitis. It is a small molecule therapy that acts as a(n) antagonist. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_5937', 'tradeNames_string': 'Lastacaft', 'drugName': 'Alcaftadine', 'drugMolecularType': 'Small molecule', 'drugActionType': 'antagonist', 'drugMechanismOfAction': 'Histamine H1 receptor antagonist', 'linkedDiseasesDrug_string': 'Allergic Conjunctivitis (EFO_0007141), Eye Allergy (EFO_0005... | general | Similarity Search, Select | Metadata |
Q22.411 | Q22 | What is Relistor? | Relistor, also known generically as Methylnaltrexone Bromide, was approved by the FDA in 2008 to treat Constipation. It is a small molecule therapy that acts as a(n) antagonist. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_2413', 'tradeNames_string': 'Relistor', 'drugName': 'Methylnaltrexone Bromide', 'drugMolecularType': 'Small molecule', 'drugActionType': 'antagonist', 'drugMechanismOfAction': 'Mu opioid receptor antagonist', 'linkedDiseasesDrug_string': 'Pancreatic Carcinoma (EFO_0002618), Constipation (H... | general | Similarity Search, Select | Metadata |
Q22.328 | Q22 | What is Corlanor? | Corlanor, also known generically as Ivabradine Hydrochloride, was approved by the FDA in 2015 to treat congestive heart failure and heart failure. It is a small molecule therapy that acts as a(n) blocker. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_32', 'tradeNames_string': 'Corlanor, Procoralan', 'drugName': 'Ivabradine', 'drugMolecularType': 'Small molecule', 'drugActionType': 'blocker', 'drugMechanismOfAction': 'Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 blocker', 'linkedDiseasesDrug_string': 'C... | general | Similarity Search, Select | Metadata |
Q22.259 | Q22 | What is Fentora? | Fentora, also known generically as Fentanyl Citrate, was approved by the FDA in 1968 to treat cancer and pain. It is a small molecule therapy that acts as a(n) agonist. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_6302', 'tradeNames_string': 'Abstral, Actiq, Breakyl, Duragesic, Duragesic-100, Duragesic-12, Duragesic-25, Duragesic-37, Duragesic-50, Duragesic-75, Durogesic, Durogesic dtrans, Effentora, Fencino, Fentalis reservoir, Fentanyl-100, Fentanyl-12, Fentanyl-25, Fentanyl-37, Fentanyl-50, Fenta... | general | Similarity Search, Select | Metadata |
Q22.423 | Q22 | What is Rydapt? | Rydapt, also known generically as Midostaurin, was approved by the FDA in 2017 to treat acute myeloid leukemia, neoplasm, mast-cell leukemia, Mastocytosis, and systemic mastocytosis. It is a small molecule therapy that acts as a(n) inhibitor. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_5664', 'tradeNames_string': 'Rydapt', 'drugName': 'Midostaurin', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Protein kinase C (PKC) inhibitor', 'linkedDiseasesDrug_string': 'Rectum Cancer (EFO_1000657), Neoplasm (EFO_0000616), Leukemia (E... | general | Similarity Search, Select | Metadata |
Q22.676 | Q22 | What is Incruse Ellipta? | Incruse Ellipta, also known generically as Umeclidinium Bromide, was approved by the FDA in 2013 to treat Airway obstruction, chronic obstructive pulmonary disease, emphysema, and chronic bronchitis. It is a small molecule therapy that acts as a(n) antagonist. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_5459', 'tradeNames_string': 'Incruse ellipta', 'drugName': 'Umeclidinium Bromide', 'drugMolecularType': 'Small molecule', 'drugActionType': 'antagonist', 'drugMechanismOfAction': 'Muscarinic acetylcholine receptor M3 antagonist', 'linkedDiseasesDrug_string': 'Chronic Bronchitis (EFO_000650... | general | Similarity Search, Select | Metadata |
Q22.193 | Q22 | What is Dyloject? | Dyloject, also known generically as Diclofenac Sodium, was approved by the FDA in 1988 to treat hemorrhage, rheumatoid arthritis, pain, and osteoarthritis. It is a small molecule therapy that acts as a(n) inhibitor. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_2818', 'tradeNames_string': 'Acoflam, Acoflam ret, Acoflam sr, Arthronac, Arthrotec 50, Arthrotec 75, Closteril 100, Defanac, Defanac retard, Defanac sr, Dexomon ret, Dexomon sr, Diclofenac sodium, Dicloflex, Dicloflex ret, Dicloflex sr, Diclomax ret, Diclomax sr, Diclotard 100 mr, Diclota... | general | Similarity Search, Select | Metadata |
Q22.445 | Q22 | What is Kloxxado? | Kloxxado, also known generically as Naloxone Hydrochloride, was approved by the FDA in 1971 to treat unipolar depression, pain, and septic shock. It is a small molecule therapy that acts as a(n) antagonist. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_3927', 'tradeNames_string': 'Evzio, Evzio (autoinjector), Kloxxado, Nalone, Naloxone, Naloxone hydrochloride, Naloxone hydrochloride (autoinjector), Narcan, Narcan neonatal, Narconil, Prenoxad, Zimhi', 'drugName': 'Naloxone Hydrochloride', 'drugMolecularType': 'Small molecule', 'drugAction... | general | Similarity Search, Select | Metadata |
Q22.623 | Q22 | What is Ibsrela? | Ibsrela, also known generically as Tenapanor Hydrochloride, was approved by the FDA in 2019 to treat irritable bowel syndrome and constipation disorder. It is a small molecule therapy that acts as a(n) inhibitor. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_3816', 'tradeNames_string': 'Ibsrela', 'drugName': 'Tenapanor Hydrochloride', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Sodium/hydrogen exchanger 3 inhibitor', 'linkedDiseasesDrug_string': 'Irritable Bowel Syndrome (EFO_0000555), Consti... | general | Similarity Search, Select | Metadata |
Q22.497 | Q22 | What is Ibrance? | Ibrance, also known generically as Palbociclib, was approved by the FDA in 2015 to treat breast carcinoma, cancer, neoplasm, breast neoplasm, and breast cancer. It is a small molecule therapy that acts as a(n) inhibitor. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_2460', 'tradeNames_string': 'Ibrance', 'drugName': 'Palbociclib', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'CDK6/cyclin D1 inhibitor', 'linkedDiseasesDrug_string': 'Cancer (MONDO_0004992), Multiple Myeloma (EFO_0001378), Pancreatic Neur... | general | Similarity Search, Select | Metadata |
Q22.97 | Q22 | What is Alphagan P? | Alphagan P, also known generically as Brimonidine Tartrate, was approved by the FDA in 1996 to treat Erythema, glaucoma, hypertension, open-angle glaucoma, rosacea, and ocular hypertension. It is a small molecule therapy that acts as a(n) agonist. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_4923', 'tradeNames_string': 'Alphagan, Alphagan p, Brimonidine tartrate, Brymont, Lumify, Mirvaso, Qoliana', 'drugName': 'Brimonidine Tartrate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Adrenergic receptor alpha-2 agonist', 'linkedDiseas... | general | Similarity Search, Select | Metadata |
Q22.183 | Q22 | What is Topicort? | Topicort, also known generically as Desoximetasone, was approved by the FDA in 1977 to treat psoriasis, skin disease, and psoriasis vulgaris. It is a small molecule therapy that acts as a(n) agonist. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_5225', 'tradeNames_string': 'Desoximetasone, Stiedex, Stiedex lp, Stiedex lpn, Topicort, Topicort lp', 'drugName': 'Desoximetasone', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Glucocorticoid receptor agonist', 'linkedDiseasesDrug_string': ... | general | Similarity Search, Select | Metadata |
Q22.305 | Q22 | What is Vantrela Er? | Vantrela Er, also known generically as Hydrocodone Bitartrate, was approved by the FDA in 1943 to treat pain. It is a small molecule therapy that acts as a(n) agonist. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_2476', 'tradeNames_string': 'Dicodid, Hysingla, Hysingla er, Mercodinone, Vantrela er, Zohydro er', 'drugName': 'Hydrocodone Bitartrate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Opioid receptors; mu/kappa/delta agonist', 'linkedDiseases... | general | Similarity Search, Select | Metadata |
Q22.648 | Q22 | What is Xeljanz Xr? | Xeljanz Xr, also known generically as Tofacitinib Citrate, was approved by the FDA in 2012 to treat rheumatoid arthritis and psoriatic arthritis. It is a small molecule therapy that acts as a(n) inhibitor. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_3515', 'tradeNames_string': 'Xeljanz, Xeljanz xr', 'drugName': 'Tofacitinib Citrate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Janus Kinase (JAK) inhibitor', 'linkedDiseasesDrug_string': 'Discoid Lupus Erythematosus (MONDO_0019558), At... | general | Similarity Search, Select | Metadata |
Q22.518 | Q22 | What is Turalio? | Turalio, also known generically as Pexidartinib Hydrochloride, was approved by the FDA in 2019 to treat Tenosynovial Giant Cell Tumor. It is a small molecule therapy that acts as a(n) inhibitor. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_4377', 'tradeNames_string': 'Turalio', 'drugName': 'Pexidartinib Hydrochloride', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Tyrosine-protein kinase receptor FLT3 inhibitor', 'linkedDiseasesDrug_string': 'Tenosynovial Giant Cell Tumor (EF... | general | Similarity Search, Select | Metadata |
Q22.649 | Q22 | What is Jynarque? | Jynarque, also known generically as Tolvaptan, was approved by the FDA in 2009 to treat Hyponatremia, cardiovascular disease, congestive heart failure, heart failure, Polycystic Kidney Disease, and polycystic kidney disease. It is a small molecule therapy that acts as a(n) antagonist. | SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) ... | [{'UUID': 'DrugGeneTargets_v2_5028', 'tradeNames_string': 'Jinarc, Jynarque, Samsca', 'drugName': 'Tolvaptan', 'drugMolecularType': 'Small molecule', 'drugActionType': 'antagonist', 'drugMechanismOfAction': 'Vasopressin V2 receptor antagonist', 'linkedDiseasesDrug_string': 'Dyspnea (HP_0002094), Chronic Kidney Disease ... | general | Similarity Search, Select | Metadata |
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