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1.14M
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14 values
Q22.457
Q22
What is Nymalize?
Nymalize, also known generically as Nimodipine, was approved by the FDA in 1988 to treat cardiovascular disease. It is a small molecule therapy that acts as a(n) blocker and antagonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_960', 'tradeNames_string': 'Nimodipine, Nimotop, Nymalize', 'drugName': 'Nimodipine', 'drugMolecularType': 'Small molecule', 'drugActionType': 'antagonist', 'drugMechanismOfAction': 'Mineralocorticoid receptor antagonist', 'linkedDiseasesDrug_string': 'Poisoning (EFO_0008546), Stroke (EFO_...
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Q22.435
Q22
What is Singulair?
Singulair, also known generically as Montelukast, was approved by the FDA in 1998 to treat Airway obstruction, seasonal allergic rhinitis, allergic rhinitis, and asthma. It is a small molecule therapy that acts as a(n) antagonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_2453', 'tradeNames_string': 'Montelukast sodium, Singulair', 'drugName': 'Montelukast Sodium', 'drugMolecularType': 'Small molecule', 'drugActionType': 'antagonist', 'drugMechanismOfAction': 'Cysteinyl leukotriene receptor 1 antagonist', 'linkedDiseasesDrug_string': 'Rhinitis (EFO_0008521)...
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Q22.6
Q22
What is Calquence?
Calquence, also known generically as Acalabrutinib Maleate, was approved by the FDA in 2022 to treat chronic lymphocytic leukemia and Mantle cell lymphoma. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_593', 'tradeNames_string': 'Calquence', 'drugName': 'Acalabrutinib', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Tyrosine-protein kinase BTK inhibitor', 'linkedDiseasesDrug_string': 'Cancer (MONDO_0004992), Multiple Myeloma (EFO_0001378),...
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Q22.692
Q22
What is Erivedge?
Erivedge, also known generically as Vismodegib, was approved by the FDA in 2012 to treat cancer, neoplasm, basal cell carcinoma, and skin basal cell carcinoma. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_5550', 'tradeNames_string': 'Erivedge', 'drugName': 'Vismodegib', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Smoothened homolog inhibitor', 'linkedDiseasesDrug_string': 'Cancer (MONDO_0004992), Nevoid Basal Cell Carcinoma Syndrome (MONDO...
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Q22.46
Q22
What is Cinvanti?
Cinvanti, also known generically as Aprepitant, was approved by the FDA in 2003 to treat Nausea and vomiting, Nausea, cancer, post operative nausea and vomiting, and Chemotherapy-induced nausea and vomiting. It is a small molecule therapy that acts as a(n) antagonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_1299', 'tradeNames_string': 'Aprepitant, Cinvanti, Emend', 'drugName': 'Aprepitant', 'drugMolecularType': 'Small molecule', 'drugActionType': 'antagonist', 'drugMechanismOfAction': 'Neurokinin 1 receptor antagonist', 'linkedDiseasesDrug_string': 'Cancer (MONDO_0004992), Multiple Myeloma (E...
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Q22.404
Q22
What is Namenda Xr?
Namenda Xr, also known generically as Memantine Hydrochloride, was approved by the FDA in 2003 to treat Dementia and Alzheimer disease. It is a small molecule therapy that acts as a(n) negative allosteric modulator.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4606', 'tradeNames_string': 'Akatinol, Ebixa, Marixino, Memantine, Memantine hydrochloride, Namenda, Namenda xr, Nemdatine, Valios', 'drugName': 'Memantine Hydrochloride', 'drugMolecularType': 'Small molecule', 'drugActionType': 'negative allosteric modulator', 'drugMechanismOfAction': 'Gl...
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Q22.532
Q22
What is Folotyn?
Folotyn, also known generically as Pralatrexate, was approved by the FDA in 2009 to treat unspecified peripheral T-cell lymphoma, cancer, neoplasm, mature T-cell and NK-cell non-Hodgkin lymphoma, and T-cell non-Hodgkin lymphoma. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_39', 'tradeNames_string': 'Folotyn', 'drugName': 'Pralatrexate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Dihydrofolate reductase inhibitor', 'linkedDiseasesDrug_string': "Sezary'S Disease (EFO_1000785), Cancer (MONDO_0004992), Multipl...
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Q22.174
Q22
What is Sprycel?
Sprycel, also known generically as Dasatinib, was approved by the FDA in 2006 to treat acute lymphoblastic leukemia, cancer, chronic myelogenous leukemia, neoplasm, childhood cancer, childhood acute lymphoblastic leukemia, and lymphoblastic lymphoma. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4598', 'tradeNames_string': 'Dasatinib, Sprycel', 'drugName': 'Dasatinib', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Platelet-derived growth factor receptor beta inhibitor', 'linkedDiseasesDrug_string': "Multiple Myeloma (EFO_0001378), ...
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Q22.17
Q22
What is Ventolin Hfa?
Ventolin Hfa, also known generically as Albuterol Sulfate, was approved by the FDA in 1982 to treat Bronchospasm, chronic obstructive pulmonary disease, and asthma. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_1434', 'tradeNames_string': 'Aerolin, Aerolin 400, Aerolin auto, Airomir, Airsalb, Albuterol, Asmasal clickhaler, Asmasal spacehaler, Asmaven, Asmavent, Cobutolin, Combivent, Combivent udvs, Ipramol steri-neb, Kentamol, Libetist, Maxivent, Proair Hfa, Proventil, Proventil Hfa, Rimasal, Sal...
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Q22.49
Q22
What is Aristada?
Aristada, also known generically as Aripiprazole Lauroxil, was approved by the FDA in 2015 to treat autism, Tourette syndrome, bipolar I disorder, major depressive disorder, and schizophrenia. It is a small molecule therapy that acts as a(n) partial agonist and antagonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4679', 'tradeNames_string': 'Aristada, Aristada initio kit', 'drugName': 'Aripiprazole Lauroxil', 'drugMolecularType': 'Small molecule', 'drugActionType': 'partial agonist', 'drugMechanismOfAction': 'Dopamine D2 receptor partial agonist', 'linkedDiseasesDrug_string': 'Autism (EFO_0003758),...
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Q22.682
Q22
What is Staxyn?
Staxyn, also known generically as Vardenafil Hydrochloride, was approved by the FDA in 2003 to treat erectile dysfunction. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4542', 'tradeNames_string': 'Levitra, Staxyn, Vardenafil hydrochloride', 'drugName': 'Vardenafil Hydrochloride', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Phosphodiesterase 5A inhibitor', 'linkedDiseasesDrug_string': 'Erectile Dysfuncti...
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Q22.646
Q22
What is Fotivda?
Fotivda, also known generically as Tivozanib Hydrochloride, was approved by the FDA in 2021 to treat renal cell carcinoma. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_2104', 'tradeNames_string': 'Fotivda', 'drugName': 'Tivozanib Hydrochloride', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Vascular endothelial growth factor receptor inhibitor', 'linkedDiseasesDrug_string': 'Renal Cell Carcinoma (EFO_0000...
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Q22.4
Q22
What is Cibinqo?
Cibinqo, also known generically as Abrocitinib, was approved by the FDA in 2022 to treat Eczema and atopic eczema. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_1422', 'tradeNames_string': 'Cibinqo', 'drugName': 'Abrocitinib', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Tyrosine-protein kinase JAK1 inhibitor', 'linkedDiseasesDrug_string': 'Eczema (HP_0000964), Psoriasis (EFO_0000676), Liver Disea...
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Q22.455
Q22
What is Tasigna?
Tasigna, also known generically as Nilotinib, was approved by the FDA in 2007 to treat cancer and neoplasm. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_6060', 'tradeNames_string': 'Tasigna', 'drugName': 'Nilotinib', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Tyrosine-protein kinase ABL inhibitor', 'linkedDiseasesDrug_string': 'Cancer (MONDO_0004992), Alzheimer Disease (MONDO_0004975), G...
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Q22.418
Q22
What is Quillivant Xr?
Quillivant Xr, also known generically as Methylphenidate Hydrochloride, was approved by the FDA in 1955 to treat attention deficit hyperactivity disorder. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_845', 'tradeNames_string': 'Adhansia xr, Aptensio xr, Concerta, Delmosart, Equasym, Equasym xl, Jornay pm, Matoride xl, Medikinet, Medikinet xl, Metadate cd, Metadate er, Methylin, Methylin er, Methylphenidate hydrochloride, Quillichew er, Quillivant xr, Relexxii, Ritalin, Ritalin la, Rita...
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Q22.321
Q22
What is Truseltiq?
Truseltiq, also known generically as Infigratinib Phosphate, was approved by the FDA in 2021 to treat cholangiocarcinoma. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_3003', 'tradeNames_string': 'Truseltiq', 'drugName': 'Infigratinib Phosphate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Fibroblast growth factor receptor inhibitor', 'linkedDiseasesDrug_string': 'Cholangiocarcinoma (EFO_0005221)', 'new...
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Q22.650
Q22
What is Samsca?
Samsca, also known generically as Tolvaptan, was approved by the FDA in 2009 to treat Hyponatremia, cardiovascular disease, congestive heart failure, heart failure, Polycystic Kidney Disease, and polycystic kidney disease. It is a small molecule therapy that acts as a(n) antagonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_5028', 'tradeNames_string': 'Jinarc, Jynarque, Samsca', 'drugName': 'Tolvaptan', 'drugMolecularType': 'Small molecule', 'drugActionType': 'antagonist', 'drugMechanismOfAction': 'Vasopressin V2 receptor antagonist', 'linkedDiseasesDrug_string': 'Dyspnea (HP_0002094), Chronic Kidney Disease ...
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Q22.287
Q22
What is Baqsimi?
Baqsimi, also known generically as Glucagon, was approved by the FDA in 1998 to treat Hypoglycemia and diabetes mellitus. It is a protein therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_1857', 'tradeNames_string': 'Baqsimi, Glucagen Hypokit, Glucagon, Glucagon Emergency Kit, Gvoke hypopen, Gvoke pfs', 'drugName': 'Glucagon', 'drugMolecularType': 'Protein', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Glucagon receptor agonist', 'linkedDiseasesDrug_string': 'Diab...
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Q22.588
Q22
What is Vesicare Ls?
Vesicare Ls, also known generically as Solifenacin Succinate, was approved by the FDA in 2004 to treat urgency urinary incontinence and overactive bladder. It is a small molecule therapy that acts as a(n) antagonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_1607', 'tradeNames_string': 'Solifenacin succinate, Vesicare, Vesicare ls', 'drugName': 'Solifenacin Succinate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'antagonist', 'drugMechanismOfAction': 'Muscarinic acetylcholine receptor M2 antagonist', 'linkedDiseasesDrug_string': '...
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Q22.289
Q22
What is Gvoke Pfs?
Gvoke Pfs, also known generically as Glucagon, was approved by the FDA in 1998 to treat Hypoglycemia and diabetes mellitus. It is a protein therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_1857', 'tradeNames_string': 'Baqsimi, Glucagen Hypokit, Glucagon, Glucagon Emergency Kit, Gvoke hypopen, Gvoke pfs', 'drugName': 'Glucagon', 'drugMolecularType': 'Protein', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Glucagon receptor agonist', 'linkedDiseasesDrug_string': 'Diab...
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Q22.684
Q22
What is Parsabiv?
Parsabiv, also known generically as Velcalcetide, was approved by the FDA in 2017 to treat chronic kidney disease, parathyroid disease, and secondary hyperparathyroidism. It is a protein therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_3935', 'tradeNames_string': 'Parsabiv', 'drugName': 'Velcalcetide', 'drugMolecularType': 'Protein', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Calcium sensing receptor agonist', 'linkedDiseasesDrug_string': 'Parathyroid Disease (EFO_0005754), Chronic Kidney Disease (EFO_0003884...
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Q22.229
Q22
What is Halaven?
Halaven, also known generically as Eribulin Mesylate, was approved by the FDA in 2010 to treat breast carcinoma, breast neoplasm, and breast cancer. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_3175', 'tradeNames_string': 'Halaven', 'drugName': 'Eribulin Mesylate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Tubulin inhibitor', 'linkedDiseasesDrug_string': 'Cancer (MONDO_0004992), Urothelial Carcinoma (EFO_0008528), Prostate Ade...
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Q22.27
Q22
What is Entereg?
Entereg, also known generically as Alvimopan, was approved by the FDA in 2008 to treat Constipation. It is a small molecule therapy that acts as a(n) antagonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4682', 'tradeNames_string': 'Entereg', 'drugName': 'Alvimopan', 'drugMolecularType': 'Small molecule', 'drugActionType': 'antagonist', 'drugMechanismOfAction': 'Mu opioid receptor antagonist', 'linkedDiseasesDrug_string': 'Fallopian Tube Cancer (MONDO_0002158), Urinary Bladder Cancer (MOND...
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Q22.554
Q22
What is Actonel?
Actonel, also known generically as Risedronate Sodium, was approved by the FDA in 1998 to treat postmenopausal osteoporosis, osteoporosis, and Paget disease. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4717', 'tradeNames_string': 'Actonel, Atelvia, Risedronate sodium', 'drugName': 'Risedronate Sodium', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Farnesyl diphosphate synthase inhibitor', 'linkedDiseasesDrug_string': 'Osteoporosis (EFO_00...
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Q22.267
Q22
What is Gilenya?
Gilenya, also known generically as Fingolimod Hydrochloride, was approved by the FDA in 2010 to treat multiple sclerosis. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4816', 'tradeNames_string': 'Gilenya', 'drugName': 'Fingolimod', 'drugMolecularType': 'Small molecule', 'drugActionType': 'binding agent', 'drugMechanismOfAction': 'Sphingosine 1-phosphate receptor binding agent', 'linkedDiseasesDrug_string': 'Anaplastic Astrocytoma (EFO_0002499), Uveitis ...
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Q22.51
Q22
What is Nuvigil?
Nuvigil, also known generically as Armodafinil, was approved by the FDA in 2007 to treat attention deficit hyperactivity disorder, obstructive sleep apnea, Sleep Disorder, narcolepsy-cataplexy syndrome, and narcolepsy. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_2926', 'tradeNames_string': 'Armodafinil, Nuvigil', 'drugName': 'Armodafinil', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Dopamine transporter inhibitor', 'linkedDiseasesDrug_string': 'Multiple Sclerosis (MONDO_0005301), Obesity (EFO_000...
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Q22.370
Q22
What is Tirosint?
Tirosint, also known generically as Levothyroxine Sodium, was approved by the FDA in 2000 to treat thyroid carcinoma, hypothyroidism, differentiated thyroid carcinoma, thyroid cancer, and congenital hypothyroidism. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_5964', 'tradeNames_string': 'Eltroxin, Ermeza, Euthyrox, Evotrox, L-thyroxine henning, Levo-t, Levolet, Levothroid, Levothyroid, Levothyroxine sodium, Levoxine, Levoxyl, Novothyrox, Soloxine, Synthroid, Thyquidity, Thyro-tabs, Thyrol L, Thyroxine, Tirosint, Tirosint-sol, Unithroid', 'drugN...
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Q22.233
Q22
What is Spravato?
Spravato, also known generically as Esketamine Hydrochloride, was approved by the FDA in 2019 to treat unipolar depression and major depressive disorder. It is a small molecule therapy that acts as a(n) negative allosteric modulator.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_817', 'tradeNames_string': 'Spravato', 'drugName': 'Esketamine Hydrochloride', 'drugMolecularType': 'Small molecule', 'drugActionType': 'negative allosteric modulator', 'drugMechanismOfAction': 'Glutamate [NMDA] receptor negative allosteric modulator', 'linkedDiseasesDrug_string': 'Tinnitu...
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Q22.38
Q22
What is Adzenys Xr-Odt?
Adzenys Xr-Odt, also known generically as Amphetamine, was approved by the FDA in 1955 to treat attention deficit hyperactivity disorder. It is a small molecule therapy that acts as a(n) releasing agent.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_1570', 'tradeNames_string': 'Adzenys er, Adzenys xr-odt, Dyanavel xr', 'drugName': 'Amphetamine', 'drugMolecularType': 'Small molecule', 'drugActionType': 'releasing agent', 'drugMechanismOfAction': 'Norepinephrine transporter releasing agent', 'linkedDiseasesDrug_string': 'Attention Defic...
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Q22.160
Q22
What is Mytesi?
Mytesi, also known generically as Crofelemer, was approved by the FDA in 2012 to treat Diarrhea and AIDS. It is a small molecule therapy that acts as a(n) inhibitor and blocker.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_2220', 'tradeNames_string': 'Fulyzaq, Mytesi, Provir, Virend', 'drugName': 'Crofelemer', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Cystic fibrosis transmembrane conductance regulator inhibitor', 'linkedDiseasesDrug_string': 'Aids (EFO_0...
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Q22.241
Q22
What is Femtrace?
Femtrace, also known generically as Estradiol Acetate, was approved by the FDA in 2003 to treat menopause and Atrophy. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_3260', 'tradeNames_string': 'Femring, Femtrace', 'drugName': 'Estradiol Acetate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Estrogen receptor alpha agonist', 'linkedDiseasesDrug_string': 'Atrophy (EFO_1000096), Menopause (EFO_0003922)', '...
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Q22.677
Q22
What is Rinvoq?
Rinvoq, also known generically as Upadacitinib, was approved by the FDA in 2019 to treat immune system disease and rheumatoid arthritis. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4653', 'tradeNames_string': 'Rinvoq', 'drugName': 'Upadacitinib', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Janus Kinase (JAK) inhibitor', 'linkedDiseasesDrug_string': "Temporal Arteritis (EFO_1001209), Vitiligo (EFO_0004208), Crohn'S D...
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Q22.380
Q22
What is Qbrelis?
Qbrelis, also known generically as Lisinopril, was approved by the FDA in 1987 to treat cardiovascular disease, congestive heart failure, diabetes mellitus, hypertension, myocardial infarction, stroke, and heart failure. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_656', 'tradeNames_string': 'Acemin, Carace, Lisinopril, Lisopress, Prinivil, Qbrelis, Zestril', 'drugName': 'Lisinopril', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Angiotensin-converting enzyme inhibitor', 'linkedDiseasesDrug_string': '...
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Q22.376
Q22
What is Tradjenta?
Tradjenta, also known generically as Linagliptin, was approved by the FDA in 2011 to treat diabetes mellitus and type 2 diabetes mellitus. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_745', 'tradeNames_string': 'Tradjenta, Trajenta', 'drugName': 'Linagliptin', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Dipeptidyl peptidase IV inhibitor', 'linkedDiseasesDrug_string': 'Diabetes Mellitus (EFO_0000400), Respiratory System...
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Q22.178
Q22
What is Firmagon?
Firmagon, also known generically as Degarelix, was approved by the FDA in 2008 to treat neoplasm. It is a protein therapy that acts as a(n) antagonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_6054', 'tradeNames_string': 'Firmagon', 'drugName': 'Degarelix Acetate', 'drugMolecularType': 'Protein', 'drugActionType': 'antagonist', 'drugMechanismOfAction': 'Gonadotropin-releasing hormone receptor antagonist', 'linkedDiseasesDrug_string': 'Prostate Cancer (MONDO_0008315), Prostate Ca...
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Q22.598
Q22
What is Alsuma?
Alsuma, also known generically as Sumatriptan Succinate, was approved by the FDA in 1992 to treat migraine disorder. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_1609', 'tradeNames_string': 'Alsuma, Imigran, Imigran 50, Imigran radis, Imigran recovery, Imigran subject, Imitrex, Imitrex statdose, Migraitan, Migraleve ultra, Onzetra xsail, Sumatriptan succinate, Sumavel dosepro, Zecuity, Zembrace symtouch', 'drugName': 'Sumatriptan Succinate', 'drugM...
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Q22.487
Q22
What is Xtampza Er?
Xtampza Er, also known generically as Oxycodone, was approved by the FDA in 1950 to treat Chronic pain, pain, drug dependence, and substance abuse. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_6046', 'tradeNames_string': 'Oxycontin, Proladone, Xtampza er', 'drugName': 'Oxycodone', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Mu opioid receptor agonist', 'linkedDiseasesDrug_string': 'Toothache (EFO_0010072), Cancer (MONDO_0004992),...
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Q22.520
Q22
What is Oraverse?
Oraverse, also known generically as Phentolamine Mesylate, was approved by the FDA in 1952 to treat adrenal gland pheochromocytoma. It is a small molecule therapy that acts as a(n) antagonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_3568', 'tradeNames_string': 'Oraverse, Phentolamine mesylate, Regitine, Rogitine', 'drugName': 'Phentolamine Mesylate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'antagonist', 'drugMechanismOfAction': 'Adrenergic receptor alpha antagonist', 'linkedDiseasesDrug_string': 'Pros...
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Q22.197
Q22
What is Tecfidera?
Tecfidera, also known generically as Dimethyl Fumarate, was approved by the FDA in 2013 to treat immune system disease and multiple sclerosis. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_3182', 'tradeNames_string': 'Tecfidera', 'drugName': 'Dimethyl Fumarate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Kelch-like ECH-associated protein 1 inhibitor', 'linkedDiseasesDrug_string': 'Psoriasis (EFO_0000676), Gliosarcoma (EFO_...
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Q22.600
Q22
What is Sumavel Dosepro?
Sumavel Dosepro, also known generically as Sumatriptan Succinate, was approved by the FDA in 1992 to treat migraine disorder. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_1609', 'tradeNames_string': 'Alsuma, Imigran, Imigran 50, Imigran radis, Imigran recovery, Imigran subject, Imitrex, Imitrex statdose, Migraitan, Migraleve ultra, Onzetra xsail, Sumatriptan succinate, Sumavel dosepro, Zecuity, Zembrace symtouch', 'drugName': 'Sumatriptan Succinate', 'drugM...
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Q22.608
Q22
What is Vyndaqel?
Vyndaqel, also known generically as Tafamidis Meglumine, was approved by the FDA in 2019 to treat cardiomyopathy, amyloidosis, and AL amyloidosis. It is a small molecule therapy that acts as a(n) stabiliser.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_8', 'tradeNames_string': 'Vyndaqel', 'drugName': 'Tafamidis Meglumine', 'drugMolecularType': 'Small molecule', 'drugActionType': 'stabiliser', 'drugMechanismOfAction': 'Transthyretin stabiliser', 'linkedDiseasesDrug_string': 'Amyloidosis (EFO_1001875), Al Amyloidosis (MONDO_0019438), Polyn...
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Q22.431
Q22
What is Exkivity?
Exkivity, also known generically as Mobocertinib Succinate, was approved by the FDA in 2021 to treat non-small cell lung carcinoma. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_1983', 'tradeNames_string': 'Exkivity', 'drugName': 'Mobocertinib Succinate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Epidermal growth factor receptor erbB1 inhibitor', 'linkedDiseasesDrug_string': 'Non-Small Cell Lung Carcinoma (EFO_...
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Q22.451
Q22
What is Nevanac?
Nevanac, also known generically as Nepafenac, was approved by the FDA in 2005 to treat inflammation, eye inflammation, and cataract. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_5261', 'tradeNames_string': 'Ilevro, Nepafenac, Nevanac', 'drugName': 'Nepafenac', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Cyclooxygenase inhibitor', 'linkedDiseasesDrug_string': 'Cataract (MONDO_0005129), Eye Inflammation (EFO_000575...
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Q22.454
Q22
What is Nicorette?
Nicorette, also known generically as Nicotine Polacrilex, was approved by the FDA in 1984 to treat nicotine dependence. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_5052', 'tradeNames_string': 'Commit, Nicorette, Nicorette (mint), Nicotine polacrilex, Thrive', 'drugName': 'Nicotine Polacrilex', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Neuronal acetylcholine receptor; alpha4/beta2 agonist', 'linkedDi...
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Q22.681
Q22
What is Levitra?
Levitra, also known generically as Vardenafil Hydrochloride, was approved by the FDA in 2003 to treat erectile dysfunction. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_2264', 'tradeNames_string': 'Levitra', 'drugName': 'Vardenafil', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Phosphodiesterase 5A inhibitor', 'linkedDiseasesDrug_string': 'Erectile Dysfunction (EFO_0004234), Pulmonary Hypertension (MONDO_...
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Q22.587
Q22
What is Xyrem?
Xyrem, also known generically as Sodium Oxybate, was approved by the FDA in 2002 to treat narcolepsy-cataplexy syndrome and narcolepsy. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4208', 'tradeNames_string': 'Xyrem', 'drugName': 'Sodium Oxybate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'GABA-B receptor agonist', 'linkedDiseasesDrug_string': 'Idiopathic Hypersomnia (MONDO_0018044), Sleep Disorder (EFO_0008568), Ess...
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Q22.606
Q22
What is Vyndamax?
Vyndamax, also known generically as Tafamidis, was approved by the FDA in 2019 to treat cardiomyopathy, amyloidosis, and AL amyloidosis. It is a small molecule therapy that acts as a(n) stabiliser.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_3770', 'tradeNames_string': 'Vyndamax, Vyndaqel', 'drugName': 'Tafamidis', 'drugMolecularType': 'Small molecule', 'drugActionType': 'stabiliser', 'drugMechanismOfAction': 'Transthyretin stabiliser', 'linkedDiseasesDrug_string': 'Amyloidosis (EFO_1001875), Al Amyloidosis (MONDO_0019438), Po...
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Q22.68
Q22
What is Lyvispah?
Lyvispah, also known generically as Baclofen, was approved by the FDA in 1977 to treat Spasticity, Rigidity, spinal cord disease, cerebral palsy, Spinal cord injury, multiple sclerosis, and brain injury. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_3627', 'tradeNames_string': 'Baclofen, Baclospas-10, Fleqsuvy, Gablofen, Kemstro, Lioresal, Lioresal intrath, Lyflex, Lyvispah, Ozobax', 'drugName': 'Baclofen', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'GABA-B receptor agonist', 'linkedDi...
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Q22.541
Q22
What is Azilect?
Azilect, also known generically as Rasagiline Mesylate, was approved by the FDA in 2006 to treat Parkinson disease. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4089', 'tradeNames_string': 'Azilect, Rasagiline mesylate', 'drugName': 'Rasagiline Mesylate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Monoamine oxidase B inhibitor', 'linkedDiseasesDrug_string': 'Multiple System Atrophy (EFO_1001050)...
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Q22.171
Q22
What is Farxiga?
Farxiga, also known generically as Dapagliflozin Propylene Glycol, was approved by the FDA in 2014 to treat heart failure and type 2 diabetes mellitus. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_1962', 'tradeNames_string': 'Farxiga', 'drugName': 'Dapagliflozin Propylene Glycol', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Sodium/glucose cotransporter 2 inhibitor', 'linkedDiseasesDrug_string': 'Type 2 Diabetes Mellitus (MONDO_0005...
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Q22.453
Q22
What is Rhopressa?
Rhopressa, also known generically as Netarsudil Dimesylate, was approved by the FDA in 2017 to treat open-angle glaucoma and ocular hypertension. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4693', 'tradeNames_string': 'Rhopressa', 'drugName': 'Netarsudil Dimesylate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Rho-associated protein kinase inhibitor', 'linkedDiseasesDrug_string': 'Open-Angle Glaucoma (EFO_0004190), Ocular Hy...
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Q22.165
Q22
What is Pradaxa?
Pradaxa, also known generically as Dabigatran Etexilate, was approved by the FDA in 2010 to treat Recurrent thrombophlebitis and thrombotic disease. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_2486', 'tradeNames_string': 'Pradaxa', 'drugName': 'Dabigatran', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Thrombin inhibitor', 'linkedDiseasesDrug_string': 'Hematoma (EFO_0010680), Ischemic Stroke (HP_0002140), Respiratory Syncytial Vi...
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Q22.313
Q22
What is Neoprofen?
Neoprofen, also known generically as Ibuprofen Lysine, was approved by the FDA in 2006 to treat Patent ductus arteriosus. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_1446', 'tradeNames_string': 'Seractil', 'drugName': 'Dexibuprofen', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Cyclooxygenase inhibitor', 'linkedDiseasesDrug_string': 'Rheumatic Disease (EFO_0005755), Fever (HP_0001945), Pain (EFO_000384...
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Q22.196
Q22
What is Trudhesa?
Trudhesa, also known generically as Dihydroergotamine Mesylate, was approved by the FDA in 1946 to treat migraine disorder. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_5316', 'tradeNames_string': 'D.h.e. 45, Diergo, Dihydergot, Dihydroergotamine mesylate, Tonopan, Trudhesa', 'drugName': 'Dihydroergotamine Mesylate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Serotonin 1d (5-HT1d) receptor agonist', 'link...
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Q22.485
Q22
What is Gelnique?
Gelnique, also known generically as Oxybutynin Chloride, was approved by the FDA in 1975 to treat overactive bladder. It is a small molecule therapy that acts as a(n) antagonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_871', 'tradeNames_string': 'Ditropan, Ditropan xl, Gelnique, Oxybutynin chloride', 'drugName': 'Oxybutynin Chloride', 'drugMolecularType': 'Small molecule', 'drugActionType': 'antagonist', 'drugMechanismOfAction': 'Muscarinic acetylcholine receptor M3 antagonist', 'linkedDiseasesDrug_strin...
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Q22.371
Q22
What is Tirosint-Sol?
Tirosint-Sol, also known generically as Levothyroxine Sodium, was approved by the FDA in 2000 to treat thyroid carcinoma, hypothyroidism, differentiated thyroid carcinoma, thyroid cancer, and congenital hypothyroidism. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_5964', 'tradeNames_string': 'Eltroxin, Ermeza, Euthyrox, Evotrox, L-thyroxine henning, Levo-t, Levolet, Levothroid, Levothyroid, Levothyroxine sodium, Levoxine, Levoxyl, Novothyrox, Soloxine, Synthroid, Thyquidity, Thyro-tabs, Thyrol L, Thyroxine, Tirosint, Tirosint-sol, Unithroid', 'drugN...
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Q22.389
Q22
What is Amitiza?
Amitiza, also known generically as Lubiprostone, was approved by the FDA in 2006 to treat Constipation, Chronic pain, irritable bowel syndrome, and constipation disorder. It is a small molecule therapy that acts as a(n) opener.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_3388', 'tradeNames_string': 'Amitiza', 'drugName': 'Lubiprostone', 'drugMolecularType': 'Small molecule', 'drugActionType': 'opener', 'drugMechanismOfAction': 'Chloride channel protein 2 opener', 'linkedDiseasesDrug_string': 'Hiv Infection (EFO_0000764), Chronic Pain (HP_0012532), Constipa...
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Q22.636
Q22
What is Kyzatrex?
Kyzatrex, also known generically as Testosterone Undecanoate, was approved by the FDA in 2014 to treat neoplasm, Klinefelter's syndrome, orchitis, hypogonadism, and hypogonadotropic hypogonadism. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_939', 'tradeNames_string': 'Andriol, Aveed, Jatenzo, Kyzatrex, Nebido, Restandol, Restandol testocap, Tlando, Undestor', 'drugName': 'Testosterone Undecanoate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Androgen Receptor agonist', 'linked...
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Q22.542
Q22
What is Lexiscan?
Lexiscan, also known generically as Regadenoson, was approved by the FDA in 2008 to treat cardiovascular disease. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_5278', 'tradeNames_string': 'Lexiscan', 'drugName': 'Regadenoson', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Adenosine A2a receptor agonist', 'linkedDiseasesDrug_string': 'Coronary Artery Disease (EFO_0001645), Retinal Artery Occlusion (E...
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Q22.155
Q22
What is Gloperba?
Gloperba, also known generically as Colchicine, was approved by the FDA in 1961 to treat gout and familial Mediterranean fever. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4743', 'tradeNames_string': 'Colchicine, Colcrys, Gloperba, Mitigare', 'drugName': 'Colchicine', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Tubulin inhibitor', 'linkedDiseasesDrug_string': "Coronary Artery Disease (EFO_0001645), Non-St E...
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Q22.495
Q22
What is Abraxane?
Abraxane, also known generically as Paclitaxel, was approved by the FDA in 1992 to treat breast carcinoma, cancer, carcinoma, neoplasm, non-small cell lung carcinoma, breast neoplasm, undifferentiated carcinoma, and breast cancer. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_2013', 'tradeNames_string': 'Abraxane, Pacitaxel, Paclitaxel, Paxene, Taxol, Taxol 100', 'drugName': 'Paclitaxel', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Tubulin inhibitor', 'linkedDiseasesDrug_string': "Ovarian Carcinoma (EFO_000107...
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Q22.504
Q22
What is Protonix?
Protonix, also known generically as Pantoprazole Sodium, was approved by the FDA in 2000 to treat Esophagitis, gastroesophageal reflux disease, and Zollinger-Ellison Syndrome. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_1903', 'tradeNames_string': 'Pantoprazole sodium, Protonix, Protonix iv', 'drugName': 'Pantoprazole Sodium', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Potassium-transporting ATPase inhibitor', 'linkedDiseasesDrug_string': 'Esophagitis (...
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Q22.230
Q22
What is Vimpat?
Vimpat, also known generically as Erlosamide, was approved by the FDA in 2008 to treat Seizure and epilepsy. It is a small molecule therapy that acts as a(n) blocker.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4004', 'tradeNames_string': 'Lacosamide, Vimpat', 'drugName': 'Erlosamide', 'drugMolecularType': 'Small molecule', 'drugActionType': 'blocker', 'drugMechanismOfAction': 'Sodium channel alpha subunit blocker', 'linkedDiseasesDrug_string': 'Migraine Disorder (MONDO_0005277), Central Nervous ...
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Q22.463
Q22
What is Inomax?
Inomax, also known generically as Nitric Oxide, was approved by the FDA in 1999 to treat Respiratory insufficiency, respiratory system disease, pulmonary arterial hypertension, respiratory failure, and pulmonary hypertension. It is a small molecule therapy that acts as a(n) activator.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_2884', 'tradeNames_string': 'Genosyl, Inomax', 'drugName': 'Nitric Oxide', 'drugMolecularType': 'Small molecule', 'drugActionType': 'activator', 'drugMechanismOfAction': 'Soluble guanylate cyclase activator', 'linkedDiseasesDrug_string': 'Cancer (MONDO_0004992), Infection (EFO_0000544), Pu...
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Q22.564
Q22
What is Neupro?
Neupro, also known generically as Rotigotine, was approved by the FDA in 2007 to treat restless legs syndrome and Parkinson disease. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_2304', 'tradeNames_string': 'Neupro', 'drugName': 'Rotigotine', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'D2-like dopamine receptor agonist', 'linkedDiseasesDrug_string': 'Alzheimer Disease (MONDO_0004975), Stroke (EFO_0000712), Parkinson...
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Q22.106
Q22
What is Posimir?
Posimir, also known generically as Bupivacaine, was approved by the FDA in 1972 to treat Hernia and pain. It is a small molecule therapy that acts as a(n) blocker.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_5747', 'tradeNames_string': 'Anekain, Exparel, Marcaine, Posimir, Sensorcaine', 'drugName': 'Bupivacaine', 'drugMolecularType': 'Small molecule', 'drugActionType': 'blocker', 'drugMechanismOfAction': 'Sodium channel protein type IV alpha subunit blocker', 'linkedDiseasesDrug_string': 'Toot...
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Q22.427
Q22
What is Kynamro?
Kynamro, also known generically as Mipomersen Sodium, was approved by the FDA in 2013 to treat cardiovascular disease and familial hypercholesterolemia. It is a oligonucleotide therapy that acts as a(n) antisense inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_3718', 'tradeNames_string': 'Kynamro', 'drugName': 'Mipomersen Sodium', 'drugMolecularType': 'Oligonucleotide', 'drugActionType': 'antisense inhibitor', 'drugMechanismOfAction': 'Apo-B 100 mRNA antisense inhibitor', 'linkedDiseasesDrug_string': 'Familial Hypercholesterolemia (EFO_0004911),...
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Q22.685
Q22
What is Zelboraf?
Zelboraf, also known generically as Vemurafenib, was approved by the FDA in 2011 to treat cancer, cutaneous melanoma, neoplasm, melanoma, and metastatic melanoma. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_3298', 'tradeNames_string': 'Zelboraf', 'drugName': 'Vemurafenib', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Serine/threonine-protein kinase B-raf inhibitor', 'linkedDiseasesDrug_string': 'Cancer (MONDO_0004992), Multiple Myeloma (EFO_0...
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Q22.534
Q22
What is Mirapex Er?
Mirapex Er, also known generically as Pramipexole Dihydrochloride, was approved by the FDA in 1997 to treat restless legs syndrome and Parkinson disease. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_5763', 'tradeNames_string': 'Mirapex, Mirapex Extended Release, Mirapex er, Pramipexole dihydrochloride', 'drugName': 'Pramipexole Dihydrochloride', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'D2-like dopamine receptor agonist', 'linkedDise...
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Q22.75
Q22
What is Qvar 80?
Qvar 80, also known generically as Beclomethasone Dipropionate, was approved by the FDA in 1976 to treat Nasal congestion, Airway obstruction, seasonal allergic rhinitis, allergic rhinitis, Rhinitis, Allergic, Perennial, and asthma. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_5013', 'tradeNames_string': 'Aerobec 100, Aerobec 50, Aerobec fte 250, Asmabec clickhaler, Asmabec spacehaler, Beclazone 100, Beclazone 100 e-breathe, Beclazone 200, Beclazone 250, Beclazone 250 e-breathe, Beclazone 50, Beclazone 50 e-breathe, Becloaqua 50, Becloforte, Becloforte e-breathe...
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Q22.118
Q22
What is Sorilux?
Sorilux, also known generically as Calcipotriene, was approved by the FDA in 1993 to treat psoriasis and psoriasis vulgaris. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_5049', 'tradeNames_string': 'Calcipotriene, Dovobet, Dovonex, Enstilar, Sorilux, Xamiol', 'drugName': 'Calcipotriene', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Vitamin D receptor agonist', 'linkedDiseasesDrug_string': 'Eczema (HP_0000964...
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Q22.413
Q22
What is Daytrana?
Daytrana, also known generically as Methylphenidate, was approved by the FDA in 1955 to treat attention deficit hyperactivity disorder and narcolepsy-cataplexy syndrome. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_2370', 'tradeNames_string': 'Concerta, Cotempla xr-odt, Daytrana', 'drugName': 'Methylphenidate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Dopamine transporter inhibitor', 'linkedDiseasesDrug_string': 'Cancer (MONDO_0004992), Alzheimer...
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Q22.680
Q22
What is Levitra?
Levitra, also known generically as Vardenafil, was approved by the FDA in 2003 to treat erectile dysfunction. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_2264', 'tradeNames_string': 'Levitra', 'drugName': 'Vardenafil', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Phosphodiesterase 5A inhibitor', 'linkedDiseasesDrug_string': 'Erectile Dysfunction (EFO_0004234), Pulmonary Hypertension (MONDO_...
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Q22.122
Q22
What is Tabrecta?
Tabrecta, also known generically as Capmatinib Hydrochloride, was approved by the FDA in 2020 to treat non-small cell lung carcinoma. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_568', 'tradeNames_string': 'Tabrecta', 'drugName': 'Capmatinib Hydrochloride', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Hepatocyte growth factor receptor inhibitor', 'linkedDiseasesDrug_string': 'Non-Small Cell Lung Carcinoma (EFO_0003...
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Q22.54
Q22
What is Saphris?
Saphris, also known generically as Asenapine Maleate, was approved by the FDA in 2009 to treat bipolar disorder, bipolar I disorder, and schizophrenia. It is a small molecule therapy that acts as a(n) antagonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4103', 'tradeNames_string': 'Saphris', 'drugName': 'Asenapine Maleate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'antagonist', 'drugMechanismOfAction': 'Serotonin 2a (5-HT2a) receptor antagonist', 'linkedDiseasesDrug_string': 'Psychosis (EFO_0005407), Bipolar I Disorder (EF...
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Q22.154
Q22
What is Colcrys?
Colcrys, also known generically as Colchicine, was approved by the FDA in 1961 to treat gout and familial Mediterranean fever. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4743', 'tradeNames_string': 'Colchicine, Colcrys, Gloperba, Mitigare', 'drugName': 'Colchicine', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Tubulin inhibitor', 'linkedDiseasesDrug_string': "Coronary Artery Disease (EFO_0001645), Non-St E...
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Q22.409
Q22
What is Janumet?
Janumet, also known generically as Metformin Hydrochloride, was approved by the FDA in 1995 to treat diabetes mellitus and type 2 diabetes mellitus. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_2411', 'tradeNames_string': 'Janumet Xr, Januvia', 'drugName': 'Sitagliptin Phosphate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Dipeptidyl peptidase IV inhibitor', 'linkedDiseasesDrug_string': 'Diabetes Mellitus (EFO_0000400), Hyperli...
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Q22.665
Q22
What is Remodulin?
Remodulin, also known generically as Treprostinil, was approved by the FDA in 2002 to treat Recurrent thrombophlebitis, pulmonary arterial hypertension, and pulmonary hypertension. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_1758', 'tradeNames_string': 'Remodulin, Tyvaso, Tyvaso dpi', 'drugName': 'Treprostinil', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Prostanoid IP receptor agonist', 'linkedDiseasesDrug_string': 'Recurrent Thrombophlebitis (HP_0004419), Pul...
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Q22.211
Q22
What is Copiktra?
Copiktra, also known generically as Duvelisib, was approved by the FDA in 2018 to treat chronic lymphocytic leukemia, neoplasm of mature B-cells, cancer, lymphoma, neoplasm, and follicular lymphoma. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_1892', 'tradeNames_string': 'Copiktra', 'drugName': 'Duvelisib', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'PI3-kinase p110-gamma subunit inhibitor', 'linkedDiseasesDrug_string': "Sezary'S Disease (EFO_1000785), Cancer (MONDO_0004992), N...
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Q22.694
Q22
What is Zontivity?
Zontivity, also known generically as Vorapaxar Sulfate, was approved by the FDA in 2014 to treat myocardial infarction, stroke, and peripheral arterial disease. It is a small molecule therapy that acts as a(n) antagonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_713', 'tradeNames_string': 'Zontivity', 'drugName': 'Vorapaxar Sulfate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'antagonist', 'drugMechanismOfAction': 'Proteinase-activated receptor 1 antagonist', 'linkedDiseasesDrug_string': 'Stroke (EFO_0000712), Peripheral Arterial Dis...
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Q22.494
Q22
What is Zeposia?
Zeposia, also known generically as Ozanimod Hydrochloride, was approved by the FDA in 2020 to treat multiple sclerosis. It is a small molecule therapy that acts as a(n) modulator.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_5399', 'tradeNames_string': 'Zeposia', 'drugName': 'Ozanimod Hydrochloride', 'drugMolecularType': 'Small molecule', 'drugActionType': 'modulator', 'drugMechanismOfAction': 'Sphingosine 1-phosphate receptor Edg-1 modulator', 'linkedDiseasesDrug_string': 'Multiple Sclerosis (MONDO_0005301)',...
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Q22.474
Q22
What is Striverdi Respimat?
Striverdi Respimat, also known generically as Olodaterol Hydrochloride, was approved by the FDA in 2014 to treat chronic obstructive pulmonary disease, emphysema, and chronic bronchitis. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_5322', 'tradeNames_string': 'Striverdi respimat', 'drugName': 'Olodaterol Hydrochloride', 'drugMolecularType': 'Small molecule', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Beta-2 adrenergic receptor agonist', 'linkedDiseasesDrug_string': 'Chronic Bronchitis (EFO_0006505), Chron...
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Q22.544
Q22
What is Orgovyx?
Orgovyx, also known generically as Relugolix, was approved by the FDA in 2020 to treat metastatic prostate cancer, neoplasm, and prostate adenocarcinoma. It is a small molecule therapy that acts as a(n) antagonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_2141', 'tradeNames_string': 'Orgovyx', 'drugName': 'Relugolix', 'drugMolecularType': 'Small molecule', 'drugActionType': 'antagonist', 'drugMechanismOfAction': 'Gonadotropin-releasing hormone receptor antagonist', 'linkedDiseasesDrug_string': 'Prostate Cancer (MONDO_0008315), Neoplasm (EFO...
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Q22.9
Q22
What is Scenesse?
Scenesse, also known generically as Afamelanotide, was approved by the FDA in 2019 to treat erythropoietic protoporphyria. It is a protein therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_6266', 'tradeNames_string': 'Scenesse', 'drugName': 'Afamelanotide', 'drugMolecularType': 'Protein', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Melanocortin receptor 1 agonist', 'linkedDiseasesDrug_string': 'Vitiligo (EFO_0004208), Ischemic Stroke (HP_0002140), Xeroderma Pigmen...
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Q22.579
Q22
What is Wegovy?
Wegovy, also known generically as Semaglutide, was approved by the FDA in 2017 to treat diabetes mellitus and type 2 diabetes mellitus. It is a protein therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_6086', 'tradeNames_string': 'Ozempic, Rybelsus, Wegovy', 'drugName': 'Semaglutide', 'drugMolecularType': 'Protein', 'drugActionType': 'agonist', 'drugMechanismOfAction': 'Glucagon-like peptide 1 receptor agonist', 'linkedDiseasesDrug_string': 'Diabetes Mellitus (EFO_0000400), Osteopenia (H...
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Q22.37
Q22
What is Adzenys Er?
Adzenys Er, also known generically as Amphetamine, was approved by the FDA in 1955 to treat attention deficit hyperactivity disorder. It is a small molecule therapy that acts as a(n) releasing agent.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_1570', 'tradeNames_string': 'Adzenys er, Adzenys xr-odt, Dyanavel xr', 'drugName': 'Amphetamine', 'drugMolecularType': 'Small molecule', 'drugActionType': 'releasing agent', 'drugMechanismOfAction': 'Norepinephrine transporter releasing agent', 'linkedDiseasesDrug_string': 'Attention Defic...
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Q22.458
Q22
What is Ofev?
Ofev, also known generically as Nintedanib, was approved by the FDA in 2014 to treat neoplasm and idiopathic pulmonary fibrosis. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_5928', 'tradeNames_string': 'Ofev, Vargatef', 'drugName': 'Nintedanib', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Fibroblast growth factor receptor inhibitor', 'linkedDiseasesDrug_string': 'Genital Neoplasm, Female (EFO_1001331), Multip...
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Q22.142
Q22
What is Winlevi?
Winlevi, also known generically as Clascoterone, was approved by the FDA in 2020 to treat acne. It is a small molecule therapy that acts as a(n) antagonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_2803', 'tradeNames_string': 'Breezula, Winlevi', 'drugName': 'Clascoterone', 'drugMolecularType': 'Small molecule', 'drugActionType': 'antagonist', 'drugMechanismOfAction': 'Androgen Receptor antagonist', 'linkedDiseasesDrug_string': 'Androgenetic Alopecia (EFO_0004191), Acne (EFO_0003894)...
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Q22.257
Q22
What is Ionsys?
Ionsys, also known generically as Fentanyl, was approved by the FDA in 1968 to treat Chronic pain, cancer, neoplasm, pain, and migraine disorder. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_6302', 'tradeNames_string': 'Abstral, Actiq, Breakyl, Duragesic, Duragesic-100, Duragesic-12, Duragesic-25, Duragesic-37, Duragesic-50, Duragesic-75, Durogesic, Durogesic dtrans, Effentora, Fencino, Fentalis reservoir, Fentanyl-100, Fentanyl-12, Fentanyl-25, Fentanyl-37, Fentanyl-50, Fenta...
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Q22.307
Q22
What is Locoid?
Locoid, also known generically as Hydrocortisone Butyrate, was approved by the FDA in 1982 to treat atopic eczema, skin disease, and seborrheic dermatitis. It is a small molecule therapy that acts as a(n) agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_1708', 'tradeNames_string': 'Acetasol hc, Acticort, Aeroseb-hc, Ala-cort, Ala-scalp, Alkindi sprinkle, Alphaderm, Anflam, Anucort-Hc, Anugesic hc, Anusol hc, Anusol plus hc, Anusol soothing relief, Anusol-Hc, Balneol-hc, Beta-hc, Calmurid hc, Canesten hc, Cetacort, Cipro hc, Cobadex, Coloc...
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Q22.530
Q22
What is Iclusig?
Iclusig, also known generically as Ponatinib Hydrochloride, was approved by the FDA in 2012 to treat acute lymphoblastic leukemia and chronic myelogenous leukemia. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_2277', 'tradeNames_string': 'Iclusig', 'drugName': 'Ponatinib', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Bcr/Abl fusion protein inhibitor', 'linkedDiseasesDrug_string': 'Cancer (MONDO_0004992), Thyroid Neoplasm (EFO_0003841), Lung Aden...
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Q22.533
Q22
What is Gavreto?
Gavreto, also known generically as Pralsetinib, was approved by the FDA in 2020 to treat cancer, neoplasm, non-small cell lung carcinoma, and medullary thyroid gland carcinoma. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_2687', 'tradeNames_string': 'Gavreto', 'drugName': 'Pralsetinib', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Tyrosine-protein kinase receptor RET inhibitor', 'linkedDiseasesDrug_string': 'Medullary Thyroid Gland Carcinoma (MONDO_0015277)...
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Q22.374
Q22
What is Xiidra?
Xiidra, also known generically as Lifitegrast, was approved by the FDA in 2016 to treat eye disease and dry eye syndrome. It is a small molecule therapy that acts as a(n) antagonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_2931', 'tradeNames_string': 'Xiidra', 'drugName': 'Lifitegrast', 'drugMolecularType': 'Small molecule', 'drugActionType': 'antagonist', 'drugMechanismOfAction': 'Integrin alpha-L/beta-2 (LFA-1) antagonist', 'linkedDiseasesDrug_string': 'Allergic Conjunctivitis (EFO_0007141), Dry Eye Syndro...
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Q22.60
Q22
What is Inlyta?
Inlyta, also known generically as Axitinib, was approved by the FDA in 2012 to treat cancer, clear cell renal carcinoma, neoplasm, papillary renal cell carcinoma, renal cell carcinoma, and renal carcinoma. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4943', 'tradeNames_string': 'Inlyta', 'drugName': 'Axitinib', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Vascular endothelial growth factor receptor inhibitor', 'linkedDiseasesDrug_string': 'Cancer (MONDO_0004992), Adenoid Cystic Carcino...
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Q22.114
Q22
What is Cabometyx?
Cabometyx, also known generically as Cabozantinib S-Malate, was approved by the FDA in 2012 to treat clear cell renal carcinoma, papillary renal cell carcinoma, papillary thyroid carcinoma, renal cell carcinoma, thyroid carcinoma, and thyroid cancer. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_3579', 'tradeNames_string': 'Cabometyx, Cometriq', 'drugName': 'Cabozantinib S-Malate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Hepatocyte growth factor receptor inhibitor', 'linkedDiseasesDrug_string': 'Ovarian Carcinoma (EFO_0001075...
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Q22.604
Q22
What is Envarsus Xr?
Envarsus Xr, also known generically as Tacrolimus, was approved by the FDA in 1994 to treat Eczema and immune system disease. It is a small molecule therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_1130', 'tradeNames_string': 'Adoport, Advagraf, Astagraf xl, Capexion, Envarsus, Envarsus xr, Modigraf, Perixis, Prograf, Protopic, Tacni, Tacrolimus, Vivadex', 'drugName': 'Tacrolimus', 'drugMolecularType': 'Small molecule', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'FK506-b...
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Q22.510
Q22
What is Empaveli?
Empaveli, also known generically as Pegcetacoplan, was approved by the FDA in 2021 to treat immune system disease. It is a protein therapy that acts as a(n) inhibitor.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4931', 'tradeNames_string': 'Empaveli', 'drugName': 'Pegcetacoplan', 'drugMolecularType': 'Protein', 'drugActionType': 'inhibitor', 'drugMechanismOfAction': 'Complement C3 inhibitor', 'linkedDiseasesDrug_string': 'Dense Deposit Disease (MONDO_0019736), Amyotrophic Lateral Sclerosis (MONDO_...
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Q22.500
Q22
What is Invega Trinza?
Invega Trinza, also known generically as Paliperidone Palmitate, was approved by the FDA in 2009 to treat schizoaffective disorder and schizophrenia. It is a small molecule therapy that acts as a(n) antagonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_5388', 'tradeNames_string': 'Invega hafyera, Invega sustenna, Invega trinza', 'drugName': 'Paliperidone Palmitate', 'drugMolecularType': 'Small molecule', 'drugActionType': 'antagonist', 'drugMechanismOfAction': 'Dopamine D2 receptor antagonist', 'linkedDiseasesDrug_string': 'Schizophrenia...
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Q22.266
Q22
What is Gilenya?
Gilenya, also known generically as Fingolimod, was approved by the FDA in 2010 to treat immune system disease. It is a small molecule therapy that acts as a(n) binding agent and agonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4816', 'tradeNames_string': 'Gilenya', 'drugName': 'Fingolimod', 'drugMolecularType': 'Small molecule', 'drugActionType': 'binding agent', 'drugMechanismOfAction': 'Sphingosine 1-phosphate receptor binding agent', 'linkedDiseasesDrug_string': 'Anaplastic Astrocytoma (EFO_0002499), Uveitis ...
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Q22.593
Q22
What is Sotylize?
Sotylize, also known generically as Sotalol Hydrochloride, was approved by the FDA in 1992 to treat Ventricular arrhythmia. It is a small molecule therapy that acts as a(n) blocker and antagonist.
SELECT UUID, tradeNames_string, drugName, drugMolecularType, drugActionType, drugMechanismOfAction, linkedDiseasesDrug_string, newLinkedTargets_string, maxClinicalTrialPhase, yearOfFirstApproval, drugIsApproved FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated` WHERE (LOWER(drugName) ...
[{'UUID': 'DrugGeneTargets_v2_4569', 'tradeNames_string': 'Beta-cardone, Betapace, Betapace af, Sorine, Sotacor, Sotalex, Sotalol hydrochloride, Sotylize', 'drugName': 'Sotalol Hydrochloride', 'drugMolecularType': 'Small molecule', 'drugActionType': 'antagonist', 'drugMechanismOfAction': 'Beta-1 adrenergic receptor ant...
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