uuid stringlengths 4 8 | template_uuid stringclasses 40
values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 133 622 | execution_results stringlengths 2 1.14M | query_type stringclasses 2
values | sql_category stringclasses 26
values | bio_category stringclasses 14
values |
|---|---|---|---|---|---|---|---|---|
Q10.722 | Q10 | Are there any TTC7A SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within TTC7A that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'TTC7A' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1247 | Q10 | Are there any SLC8B1 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within SLC8B1 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'SLC8B1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1236 | Q10 | Are there any RP11-245J24.1 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within RP11-245J24.1 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'RP11-245J24.1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1076 | Q10 | Are there any GPNMB SNPs that have a statistically significant association with Parkinson's Disease? | Yes, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there is at least 13 GPNMB SNP that are significantly associatied with Parkinson's Disease:
• rs466225 (GWAS p-value: 4.66e-09; b-value: 0.1037)
• rs858240 (GWAS p-value: 8.48e-09; b-value: -0.1002)
• rs858273 ... | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'GPNMB' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_447894', 'Gene': 'GPNMB', 'topRSID': 'rs466225', 'p_GWAS': 4.663443e-09, 'b_GWAS': 0.1037}, {'UUID': 'NDD_SMR_genes_all_update_text_1386055', 'Gene': 'GPNMB', 'topRSID': 'rs858240', 'p_GWAS': 8.480402e-09, 'b_GWAS': -0.1002}, {'UUID': 'NDD_SMR_genes_all_update_text_1461950', 'Ge... | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1907 | Q10 | Are there any LINC00595 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within LINC00595 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'LINC00595' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.264 | Q10 | Are there any STX1B SNPs that have a statistically significant association with Parkinson's Disease? | Yes, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are at least 3 STX1B SNPs that are significantly associatied with Parkinson's Disease:
• rs1046276 (GWAS p-value: 2.57e-10; b-value: -0.1176)
• rs13708 (GWAS p-value: 4.25e-09; b-value: -0.1075)
• rs23058... | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'STX1B' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_974675', 'Gene': 'STX1B', 'topRSID': 'rs1046276', 'p_GWAS': 2.572307e-10, 'b_GWAS': -0.1176}, {'UUID': 'NDD_SMR_genes_all_update_text_1639762', 'Gene': 'STX1B', 'topRSID': 'rs2305880', 'p_GWAS': 3.481743e-09, 'b_GWAS': -0.1081}, {'UUID': 'NDD_SMR_genes_all_update_text_1435343', ... | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1437 | Q10 | Are there any RP11-521O16.1 SNPs that have a statistically significant association with Alzheimer's Disease? | Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are at least 2 RP11-521O16.1 SNPs that are significantly associatied with Alzheimer's Disease:
• rs12617974 (GWAS p-value: 4.92e-09; b-value: -0.0585)
• rs2404175 (GWAS p-value: 5.22e-09; b-value: 0.0584) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'RP11-521O16.1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_631113', 'Gene': 'RP11-521O16.1', 'topRSID': 'rs12617974', 'p_GWAS': 4.91573e-09, 'b_GWAS': 0.0585}, {'UUID': 'NDD_SMR_genes_all_update_text_46328', 'Gene': 'RP11-521O16.1', 'topRSID': 'rs12617974', 'p_GWAS': 4.91573e-09, 'b_GWAS': -0.0585}, {'UUID': 'NDD_SMR_genes_all_update_te... | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1339 | Q10 | Are there any ACMSD SNPs that have a statistically significant association with Parkinson's Disease? | Yes, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are at least 2 ACMSD SNPs that are significantly associatied with Parkinson's Disease:
• rs4953936 (GWAS p-value: 1.26e-11; b-value: -0.1192)
• rs7599054 (GWAS p-value: 2.67e-12; b-value: -0.1224) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'ACMSD' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1019157', 'Gene': 'ACMSD', 'topRSID': 'rs7599054', 'p_GWAS': 2.666137e-12, 'b_GWAS': -0.1224}, {'UUID': 'NDD_SMR_genes_all_update_text_1019156', 'Gene': 'ACMSD', 'topRSID': 'rs4953936', 'p_GWAS': 1.263771e-11, 'b_GWAS': -0.1192}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.243 | Q10 | Are there any C21orf33 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within C21orf33 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'C21orf33' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1010 | Q10 | Are there any TPRG1 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within TPRG1 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'TPRG1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.685 | Q10 | Are there any SRGN SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within SRGN that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'SRGN' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1268 | Q10 | Are there any CPA2 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within CPA2 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'CPA2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1475 | Q10 | Are there any AC012370.3 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within AC012370.3 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'AC012370.3' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1502 | Q10 | Are there any LPHN2 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within LPHN2 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'LPHN2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.370 | Q10 | Are there any NALCN SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within NALCN that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'NALCN' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1009 | Q10 | Are there any C7orf55-LUC7L2 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within C7orf55-LUC7L2 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'C7orf55-LUC7L2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1239 | Q10 | Are there any SLC3A2 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within SLC3A2 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'SLC3A2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.595 | Q10 | Are there any MOBKL2B SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | Yes, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there is at least 1 MOBKL2B SNP that are significantly associatied with Amyotrophic Lateral Sclerosis:
• rs10812605 (GWAS p-value: 4.84e-18; b-value: 0.1212) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'MOBKL2B' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_745096', 'Gene': 'MOBKL2B', 'topRSID': 'rs10812605', 'p_GWAS': 4.837363e-18, 'b_GWAS': 0.1212}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.728 | Q10 | Are there any QSOX1 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within QSOX1 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'QSOX1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.486 | Q10 | Are there any RAB7L1 SNPs that have a statistically significant association with Parkinson's Disease? | Yes, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are at least 2 RAB7L1 SNPs that are significantly associatied with Parkinson's Disease:
• rs823118 (GWAS p-value: 5.15e-09; b-value: 0.0999)
• rs708723 (GWAS p-value: 1.03e-08; b-value: -0.0979) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'RAB7L1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1592939', 'Gene': 'RAB7L1', 'topRSID': 'rs823118', 'p_GWAS': 5.154522e-09, 'b_GWAS': 0.0999}, {'UUID': 'NDD_SMR_genes_all_update_text_1634804', 'Gene': 'RAB7L1', 'topRSID': 'rs823118', 'p_GWAS': 5.154522e-09, 'b_GWAS': 0.0999}, {'UUID': 'NDD_SMR_genes_all_update_text_1259430', '... | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.573 | Q10 | Are there any MBD5 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within MBD5 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'MBD5' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.74 | Q10 | Are there any TUSC2 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within TUSC2 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'TUSC2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.635 | Q10 | Are there any SORL1 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within SORL1 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'SORL1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.262 | Q10 | Are there any SPATA7 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within SPATA7 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'SPATA7' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.52 | Q10 | Are there any SPPL2C SNPs that have a statistically significant association with Parkinson's Disease? | Yes, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are at least 5 SPPL2C SNPs that are significantly associatied with Parkinson's Disease:
• rs2532233 (GWAS p-value: 1.47e-19; b-value: 0.2325)
• rs55980621 (GWAS p-value: 3.91e-21; b-value: 0.2538)
• rs560... | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'SPPL2C' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1242272', 'Gene': 'SPPL2C', 'topRSID': 'rs17577369', 'p_GWAS': 3.436243e-21, 'b_GWAS': -0.257}, {'UUID': 'NDD_SMR_genes_all_update_text_1147254', 'Gene': 'SPPL2C', 'topRSID': 'rs55980621', 'p_GWAS': 3.912023e-21, 'b_GWAS': 0.2538}, {'UUID': 'NDD_SMR_genes_all_update_text_1710348... | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.201 | Q10 | Are there any NR1H3 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within NR1H3 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'NR1H3' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.432 | Q10 | Are there any RP13-1032I1.7 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within RP13-1032I1.7 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'RP13-1032I1.7' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1563 | Q10 | Are there any CTSE SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within CTSE that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'CTSE' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.336 | Q10 | Are there any PKD1L1 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within PKD1L1 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'PKD1L1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1557 | Q10 | Are there any PCGF2 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within PCGF2 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'PCGF2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1539 | Q10 | Are there any CMTM2 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within CMTM2 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'CMTM2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.426 | Q10 | Are there any EPOR SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within EPOR that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'EPOR' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.637 | Q10 | Are there any MGST1 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within MGST1 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'MGST1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.941 | Q10 | Are there any GALNT8 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within GALNT8 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'GALNT8' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.993 | Q10 | Are there any CEP170P1 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within CEP170P1 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'CEP170P1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.868 | Q10 | Are there any ZNF429 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within ZNF429 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'ZNF429' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1951 | Q10 | Are there any PABPC1 SNPs that have a statistically significant association with Alzheimer's Disease? | Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are at least 2 PABPC1 SNPs that are significantly associatied with Alzheimer's Disease:
• rs1693551 (GWAS p-value: 1.46e-08; b-value: 0.0459)
• rs1693560 (GWAS p-value: 3.54e-08; b-value: 0.0452) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'PABPC1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1608146', 'Gene': 'PABPC1', 'topRSID': 'rs1693551', 'p_GWAS': 1.456022e-08, 'b_GWAS': -0.0459}, {'UUID': 'NDD_SMR_genes_all_update_text_1393075', 'Gene': 'PABPC1', 'topRSID': 'rs1693551', 'p_GWAS': 1.456022e-08, 'b_GWAS': 0.0459}, {'UUID': 'NDD_SMR_genes_all_update_text_1453596'... | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.558 | Q10 | Are there any AC069363.1 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within AC069363.1 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'AC069363.1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.433 | Q10 | Are there any PPM1H SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within PPM1H that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'PPM1H' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1777 | Q10 | Are there any MGC57346 SNPs that have a statistically significant association with Alzheimer's Disease? | Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there is at least 1 MGC57346 SNP that are significantly associatied with Alzheimer's Disease:
• rs62056790 (GWAS p-value: 3.01e-08; b-value: -0.0543) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'MGC57346' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_591168', 'Gene': 'MGC57346', 'topRSID': 'rs62056790', 'p_GWAS': 3.010649e-08, 'b_GWAS': -0.0543}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1834 | Q10 | Are there any NSF SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within NSF that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'NSF' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1977 | Q10 | Are there any TRAF1 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within TRAF1 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'TRAF1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1506 | Q10 | Are there any PHF20L1 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within PHF20L1 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'PHF20L1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1622 | Q10 | Are there any DND1P1 SNPs that have a statistically significant association with Progressive supranuclear palsy? | Yes, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are at least 5 DND1P1 SNPs that are significantly associatied with Progressive supranuclear palsy:
• rs169201 (GWAS p-value: 8.55e-46; b-value: -1.588)
• rs1981997 (GWAS p-value: 1.79e-51; b-value: 1.715)
• rs163529... | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'DND1P1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1478184', 'Gene': 'DND1P1', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1388479', 'Gene': 'DND1P1', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1604710',... | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.404 | Q10 | Are there any CRHR1 SNPs that have a statistically significant association with Progressive supranuclear palsy? | Yes, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are at least 6 CRHR1 SNPs that are significantly associatied with Progressive supranuclear palsy:
• rs393152 (GWAS p-value: 8.30e-51; b-value: 1.652)
• rs12373139 (GWAS p-value: 4.65e-51; b-value: 1.688)
• rs2074404... | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'CRHR1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1336289', 'Gene': 'CRHR1', 'topRSID': 'rs8070723', 'p_GWAS': 2.234221e-51, 'b_GWAS': 1.7039}, {'UUID': 'NDD_SMR_genes_all_update_text_560849', 'Gene': 'CRHR1', 'topRSID': 'rs12373139', 'p_GWAS': 4.6506369999999996e-51, 'b_GWAS': 1.6879}, {'UUID': 'NDD_SMR_genes_all_update_text_1... | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1791 | Q10 | Are there any SPIRE2 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within SPIRE2 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'SPIRE2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.195 | Q10 | Are there any PLEKHO2 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within PLEKHO2 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'PLEKHO2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1281 | Q10 | Are there any ZNF668 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within ZNF668 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'ZNF668' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1381 | Q10 | Are there any CD96 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within CD96 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'CD96' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.677 | Q10 | Are there any DND1P1 SNPs that have a statistically significant association with Parkinson's Disease? | Yes, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are at least 8 DND1P1 SNPs that are significantly associatied with Parkinson's Disease:
• rs1724390 (GWAS p-value: 5.14e-16; b-value: -0.21)
• rs57213017 (GWAS p-value: 2.30e-16; b-value: -0.2117)
• rs199... | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'DND1P1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1730060', 'Gene': 'DND1P1', 'topRSID': 'rs55974014', 'p_GWAS': 8.840428e-21, 'b_GWAS': -0.2571}, {'UUID': 'NDD_SMR_genes_all_update_text_1476423', 'Gene': 'DND1P1', 'topRSID': 'rs55974014', 'p_GWAS': 8.840428e-21, 'b_GWAS': -0.2571}, {'UUID': 'NDD_SMR_genes_all_update_text_16795... | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.795 | Q10 | Are there any FFAR2 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within FFAR2 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'FFAR2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1463 | Q10 | Are there any FMNL1 SNPs that have a statistically significant association with Parkinson's Disease? | Yes, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are at least 3 FMNL1 SNPs that are significantly associatied with Parkinson's Disease:
• rs12150464 (GWAS p-value: 5.19e-21; b-value: 0.253)
• rs62062283 (GWAS p-value: 5.71e-21; b-value: -0.2377)
• rs620... | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'FMNL1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_19643', 'Gene': 'FMNL1', 'topRSID': 'rs12150464', 'p_GWAS': 5.192914e-21, 'b_GWAS': 0.253}, {'UUID': 'NDD_SMR_genes_all_update_text_1191159', 'Gene': 'FMNL1', 'topRSID': 'rs62062283', 'p_GWAS': 5.707835e-21, 'b_GWAS': -0.2377}, {'UUID': 'NDD_SMR_genes_all_update_text_1435910', '... | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1457 | Q10 | Are there any CTC-513N18.7 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within CTC-513N18.7 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'CTC-513N18.7' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.144 | Q10 | Are there any RP11-339B21.10 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within RP11-339B21.10 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'RP11-339B21.10' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1188 | Q10 | Are there any MIR4453 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within MIR4453 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'MIR4453' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.3 | Q10 | Are there any HIRIP3 SNPs that have a statistically significant association with Alzheimer's Disease? | Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are at least 2 HIRIP3 SNPs that are significantly associatied with Alzheimer's Disease:
• rs4077410 (GWAS p-value: 1.26e-08; b-value: 0.0461)
• rs8054556 (GWAS p-value: 2.13e-09; b-value: -0.0491) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'HIRIP3' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_577414', 'Gene': 'HIRIP3', 'topRSID': 'rs8054556', 'p_GWAS': 2.12692e-09, 'b_GWAS': -0.0491}, {'UUID': 'NDD_SMR_genes_all_update_text_109449', 'Gene': 'HIRIP3', 'topRSID': 'rs4077410', 'p_GWAS': 1.260329e-08, 'b_GWAS': 0.0461}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.743 | Q10 | Are there any TAFA4 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within TAFA4 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'TAFA4' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1871 | Q10 | Are there any RAB3GAP1 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within RAB3GAP1 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'RAB3GAP1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1516 | Q10 | Are there any RP11-342K6.4 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within RP11-342K6.4 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'RP11-342K6.4' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.343 | Q10 | Are there any CD55 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within CD55 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'CD55' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.626 | Q10 | Are there any ARL17B SNPs that have a statistically significant association with Parkinson's Disease? | Yes, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are at least 4 ARL17B SNPs that are significantly associatied with Parkinson's Disease:
• rs9896243 (GWAS p-value: 3.17e-18; b-value: -0.2185)
• rs199451 (GWAS p-value: 3.35e-19; b-value: 0.2266)
• rs1995... | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'ARL17B' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_30030', 'Gene': 'ARL17B', 'topRSID': 'rs199451', 'p_GWAS': 3.3508139999999995e-19, 'b_GWAS': 0.2266}, {'UUID': 'NDD_SMR_genes_all_update_text_1147258', 'Gene': 'ARL17B', 'topRSID': 'rs538628', 'p_GWAS': 5.933073e-19, 'b_GWAS': 0.225}, {'UUID': 'NDD_SMR_genes_all_update_text_3301... | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.484 | Q10 | Are there any KTN1-AS1 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within KTN1-AS1 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'KTN1-AS1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.532 | Q10 | Are there any RP11-154D6.1 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within RP11-154D6.1 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'RP11-154D6.1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.268 | Q10 | Are there any AC010150.1 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within AC010150.1 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'AC010150.1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1390 | Q10 | Are there any RP11-175P19.2 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within RP11-175P19.2 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'RP11-175P19.2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.681 | Q10 | Are there any SKP2 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within SKP2 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'SKP2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.492 | Q10 | Are there any ICA1L SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within ICA1L that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'ICA1L' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.445 | Q10 | Are there any ITGB1BP1 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within ITGB1BP1 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'ITGB1BP1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.274 | Q10 | Are there any CTC-503J8.6 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within CTC-503J8.6 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'CTC-503J8.6' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.187 | Q10 | Are there any INTS7 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within INTS7 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'INTS7' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.950 | Q10 | Are there any SCARA3 SNPs that have a statistically significant association with Alzheimer's Disease? | Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are at least 3 SCARA3 SNPs that are significantly associatied with Alzheimer's Disease:
• rs536332 (GWAS p-value: 1.32e-08; b-value: -0.0466)
• rs530324 (GWAS p-value: 5.57e-09; b-value: -0.0478)
• rs933190... | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'SCARA3' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1199214', 'Gene': 'SCARA3', 'topRSID': 'rs9331908', 'p_GWAS': 9.372289e-11, 'b_GWAS': 0.0557}, {'UUID': 'NDD_SMR_genes_all_update_text_78269', 'Gene': 'SCARA3', 'topRSID': 'rs530324', 'p_GWAS': 5.567094e-09, 'b_GWAS': -0.0478}, {'UUID': 'NDD_SMR_genes_all_update_text_78268', 'Ge... | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.247 | Q10 | Are there any LRRC37A SNPs that have a statistically significant association with Alzheimer's Disease? | Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are at least 5 LRRC37A SNPs that are significantly associatied with Alzheimer's Disease:
• rs2696466 (GWAS p-value: 4.51e-10; b-value: 0.053)
• rs62055515 (GWAS p-value: 3.19e-08; b-value: 0.0542)
• rs72250... | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'LRRC37A' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1598273', 'Gene': 'LRRC37A', 'topRSID': 'rs4510068', 'p_GWAS': 1.331504e-10, 'b_GWAS': -0.0546}, {'UUID': 'NDD_SMR_genes_all_update_text_1268121', 'Gene': 'LRRC37A', 'topRSID': 'rs4510068', 'p_GWAS': 1.331504e-10, 'b_GWAS': -0.0546}, {'UUID': 'NDD_SMR_genes_all_update_text_16525... | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1100 | Q10 | Are there any FAM96A SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within FAM96A that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'FAM96A' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1018 | Q10 | Are there any ZNF771 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within ZNF771 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'ZNF771' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.590 | Q10 | Are there any MMRN1 SNPs that have a statistically significant association with Parkinson's Disease? | Yes, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there is at least 12 MMRN1 SNP that are significantly associatied with Parkinson's Disease:
• rs28532850 (GWAS p-value: 1.13e-14; b-value: 0.3383)
• rs1866995 (GWAS p-value: 7.81e-14; b-value: 0.3236)
• rs79093... | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'MMRN1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1366625', 'Gene': 'MMRN1', 'topRSID': 'rs28532850', 'p_GWAS': 1.129613e-14, 'b_GWAS': 0.3383}, {'UUID': 'NDD_SMR_genes_all_update_text_1475008', 'Gene': 'MMRN1', 'topRSID': 'rs1866995', 'p_GWAS': 7.812441e-14, 'b_GWAS': 0.3236}, {'UUID': 'NDD_SMR_genes_all_update_text_1236436', ... | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1629 | Q10 | Are there any PTPRR SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within PTPRR that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'PTPRR' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.535 | Q10 | Are there any RP13-638C3.3 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within RP13-638C3.3 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'RP13-638C3.3' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.899 | Q10 | Are there any ANGPTL7 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within ANGPTL7 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'ANGPTL7' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1483 | Q10 | Are there any SERPINA10 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within SERPINA10 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'SERPINA10' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1109 | Q10 | Are there any KANSL1 SNPs that have a statistically significant association with Parkinson's Disease? | Yes, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are at least 24 KANSL1 SNPs that are significantly associatied with Parkinson's Disease:
• rs8712 (GWAS p-value: 3.71e-21; b-value: -0.2379)
• rs17661015 (GWAS p-value: 4.30e-21; b-value: -0.2573)
• rs196... | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'KANSL1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_491134', 'Gene': 'KANSL1', 'topRSID': 'rs8712', 'p_GWAS': 3.710891e-21, 'b_GWAS': -0.2379}, {'UUID': 'NDD_SMR_genes_all_update_text_491138', 'Gene': 'KANSL1', 'topRSID': 'rs17661015', 'p_GWAS': 4.30481e-21, 'b_GWAS': -0.2573}, {'UUID': 'NDD_SMR_genes_all_update_text_491141', 'Ge... | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.421 | Q10 | Are there any APOL6 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within APOL6 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'APOL6' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.277 | Q10 | Are there any COLGALT1 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within COLGALT1 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'COLGALT1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1174 | Q10 | Are there any RP11-9G1.3 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within RP11-9G1.3 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'RP11-9G1.3' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1487 | Q10 | Are there any LACTB SNPs that have a statistically significant association with Alzheimer's Disease? | Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there is at least 1 LACTB SNP that are significantly associatied with Alzheimer's Disease:
• rs34367270 (GWAS p-value: 1.39e-08; b-value: 0.0471) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'LACTB' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1446595', 'Gene': 'LACTB', 'topRSID': 'rs34367270', 'p_GWAS': 1.389329e-08, 'b_GWAS': 0.0471}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1456 | Q10 | Are there any LRRC37A SNPs that have a statistically significant association with Progressive supranuclear palsy? | Yes, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are at least 5 LRRC37A SNPs that are significantly associatied with Progressive supranuclear palsy:
• rs7225002 (GWAS p-value: 1.75e-11; b-value: -0.3874)
• rs8070723 (GWAS p-value: 2.23e-51; b-value: -1.704)
• rs19... | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'LRRC37A' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1444274', 'Gene': 'LRRC37A', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_30482', 'Gene': 'LRRC37A', 'topRSID': 'rs8070723', 'p_GWAS': 2.234221e-51, 'b_GWAS': -1.7039}, {'UUID': 'NDD_SMR_genes_all_update_text_1646048'... | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.253 | Q10 | Are there any POLR2L SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within POLR2L that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'POLR2L' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.419 | Q10 | Are there any CHRNA1 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within CHRNA1 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'CHRNA1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1590 | Q10 | Are there any C8orf33 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within C8orf33 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'C8orf33' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1895 | Q10 | Are there any GAK SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within GAK that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'GAK' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.582 | Q10 | Are there any HSD17B2 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within HSD17B2 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'HSD17B2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.314 | Q10 | Are there any C16orf45 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within C16orf45 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'C16orf45' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1962 | Q10 | Are there any VAC14-AS1 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within VAC14-AS1 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'VAC14-AS1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.387 | Q10 | Are there any ADORA2B SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within ADORA2B that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'ADORA2B' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.541 | Q10 | Are there any KCTD13 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within KCTD13 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'KCTD13' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.431 | Q10 | Are there any OR10AB1P SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within OR10AB1P that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'OR10AB1P' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.657 | Q10 | Are there any C14orf142 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within C14orf142 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'C14orf142' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1642 | Q10 | Are there any RP11-295M18.2 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within RP11-295M18.2 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'RP11-295M18.2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1318 | Q10 | Are there any SDCBP SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within SDCBP that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'SDCBP' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1358 | Q10 | Are there any CD2AP SNPs that have a statistically significant association with Alzheimer's Disease? | Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are at least 6 CD2AP SNPs that are significantly associatied with Alzheimer's Disease:
• rs9349407 (GWAS p-value: 6.02e-12; b-value: 0.0626)
• rs1004173 (GWAS p-value: 7.03e-12; b-value: 0.0624)
• rs7738044... | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'CD2AP' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_67370', 'Gene': 'CD2AP', 'topRSID': 'rs9349407', 'p_GWAS': 6.022304e-12, 'b_GWAS': 0.0626}, {'UUID': 'NDD_SMR_genes_all_update_text_67371', 'Gene': 'CD2AP', 'topRSID': 'rs1004173', 'p_GWAS': 7.025137e-12, 'b_GWAS': 0.0624}, {'UUID': 'NDD_SMR_genes_all_update_text_67374', 'Gene':... | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.414 | Q10 | Are there any RP11-209E8.1 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within RP11-209E8.1 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'RP11-209E8.1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
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