Datasets:

uuid
stringlengths
4
8
template_uuid
stringclasses
40 values
question
stringlengths
13
193
answer
stringlengths
29
2.2k
benchmark_query
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138
627
execution_results
stringlengths
2
1.14M
query_type
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2 values
sql_category
stringclasses
26 values
bio_category
stringclasses
14 values
Q10.686
Q10
Are there any RPL3L SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within RPL3L that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'RPL3L' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.1485
Q10
Are there any WHAMM SNPs that have a statistically significant association with Progressive supranuclear palsy?
No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within WHAMM that are significantly associated with Progressive supranuclear palsy.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'WHAMM' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.1455
Q10
Are there any NR1H3 SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within NR1H3 that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'NR1H3' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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Q10.1486
Q10
Are there any BHLHA15 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within BHLHA15 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'BHLHA15' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.1292
Q10
Are there any FAM73B SNPs that have a statistically significant association with Progressive supranuclear palsy?
No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within FAM73B that are significantly associated with Progressive supranuclear palsy.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'FAM73B' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.1232
Q10
Are there any ASPHD1 SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within ASPHD1 that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'ASPHD1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.525
Q10
Are there any ELOVL7 SNPs that have a statistically significant association with Parkinson's Disease?
Yes, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are at least 3 ELOVL7 SNPs that are significantly associatied with Parkinson's Disease: • rs9291695 (GWAS p-value: 4.84e-08; b-value: -0.1648) • rs4700390 (GWAS p-value: 2.65e-10; b-value: 0.1788) • rs34435485 (GWAS p-value: 1.67e-08; b-value: 0.114)
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'ELOVL7' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[{'UUID': 'NDD_SMR_genes_all_update_text_1323825', 'Gene': 'ELOVL7', 'topRSID': 'rs4700390', 'p_GWAS': 2.649337e-10, 'b_GWAS': 0.1788}, {'UUID': 'NDD_SMR_genes_all_update_text_1675879', 'Gene': 'ELOVL7', 'topRSID': 'rs34435485', 'p_GWAS': 1.665652e-08, 'b_GWAS': 0.114}, {'UUID': 'NDD_SMR_genes_all_update_text_435603', 'Gene': 'ELOVL7', 'topRSID': 'rs9291695', 'p_GWAS': 4.843727e-08, 'b_GWAS': -0.1648}]
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Q10.1654
Q10
Are there any RP11-707O23.5 SNPs that have a statistically significant association with Progressive supranuclear palsy?
Yes, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are at least 3 RP11-707O23.5 SNPs that are significantly associatied with Progressive supranuclear palsy: • rs1981997 (GWAS p-value: 1.79e-51; b-value: 1.715) • rs12373139 (GWAS p-value: 4.65e-51; b-value: 1.688) • rs11012 (GWAS p-value: 2.11e-42; b-value: 1.608)
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'RP11-707O23.5' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[{'UUID': 'NDD_SMR_genes_all_update_text_1264979', 'Gene': 'RP11-707O23.5', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1464415', 'Gene': 'RP11-707O23.5', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1478185', 'Gene': 'RP11-707O23.5', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1732392', 'Gene': 'RP11-707O23.5', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1596820', 'Gene': 'RP11-707O23.5', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1714152', 'Gene': 'RP11-707O23.5', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1388480', 'Gene': 'RP11-707O23.5', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1452480', 'Gene': 'RP11-707O23.5', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1283699', 'Gene': 'RP11-707O23.5', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1170871', 'Gene': 'RP11-707O23.5', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1489535', 'Gene': 'RP11-707O23.5', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1604711', 'Gene': 'RP11-707O23.5', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1684932', 'Gene': 'RP11-707O23.5', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1194213', 'Gene': 'RP11-707O23.5', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1375926', 'Gene': 'RP11-707O23.5', 'topRSID': 'rs12373139', 'p_GWAS': 4.650637e-51, 'b_GWAS': 1.6879}, {'UUID': 'NDD_SMR_genes_all_update_text_1336286', 'Gene': 'RP11-707O23.5', 'topRSID': 'rs12373139', 'p_GWAS': 4.650637e-51, 'b_GWAS': 1.6879}, {'UUID': 'NDD_SMR_genes_all_update_text_1579418', 'Gene': 'RP11-707O23.5', 'topRSID': 'rs11012', 'p_GWAS': 2.1076899999999998e-42, 'b_GWAS': 1.6076}, {'UUID': 'NDD_SMR_genes_all_update_text_1646040', 'Gene': 'RP11-707O23.5', 'topRSID': 'rs11012', 'p_GWAS': 2.10769e-42, 'b_GWAS': 1.6076}]
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Q10.908
Q10
Are there any GCHFR SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within GCHFR that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'GCHFR' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.1904
Q10
Are there any FAM228B SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within FAM228B that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'FAM228B' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.1242
Q10
Are there any SPHKAP SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within SPHKAP that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'SPHKAP' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.24
Q10
Are there any TNNC2 SNPs that have a statistically significant association with Progressive supranuclear palsy?
No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within TNNC2 that are significantly associated with Progressive supranuclear palsy.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'TNNC2' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.779
Q10
Are there any RETN SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within RETN that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'RETN' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.65
Q10
Are there any CACNA1G SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within CACNA1G that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'CACNA1G' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.1366
Q10
Are there any RP4-635E18.8 SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within RP4-635E18.8 that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'RP4-635E18.8' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.191
Q10
Are there any B3GNT5 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within B3GNT5 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'B3GNT5' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.1630
Q10
Are there any AP000436.4 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within AP000436.4 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'AP000436.4' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.1395
Q10
Are there any LRRC37A4P SNPs that have a statistically significant association with Progressive supranuclear palsy?
Yes, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are at least 3 LRRC37A4P SNPs that are significantly associatied with Progressive supranuclear palsy: • rs1981997 (GWAS p-value: 1.79e-51; b-value: 1.715) • rs12373139 (GWAS p-value: 4.65e-51; b-value: 1.688) • rs11012 (GWAS p-value: 2.11e-42; b-value: 1.608)
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'LRRC37A4P' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[{'UUID': 'NDD_SMR_genes_all_update_text_1464413', 'Gene': 'LRRC37A4P', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1452478', 'Gene': 'LRRC37A4P', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1732390', 'Gene': 'LRRC37A4P', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1489533', 'Gene': 'LRRC37A4P', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1264977', 'Gene': 'LRRC37A4P', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1596818', 'Gene': 'LRRC37A4P', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1170869', 'Gene': 'LRRC37A4P', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1714149', 'Gene': 'LRRC37A4P', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1283697', 'Gene': 'LRRC37A4P', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1478182', 'Gene': 'LRRC37A4P', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1388478', 'Gene': 'LRRC37A4P', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1604709', 'Gene': 'LRRC37A4P', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1194210', 'Gene': 'LRRC37A4P', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1684928', 'Gene': 'LRRC37A4P', 'topRSID': 'rs12373139', 'p_GWAS': 4.650637e-51, 'b_GWAS': 1.6879}, {'UUID': 'NDD_SMR_genes_all_update_text_1336282', 'Gene': 'LRRC37A4P', 'topRSID': 'rs12373139', 'p_GWAS': 4.650637e-51, 'b_GWAS': 1.6879}, {'UUID': 'NDD_SMR_genes_all_update_text_1375923', 'Gene': 'LRRC37A4P', 'topRSID': 'rs12373139', 'p_GWAS': 4.650637e-51, 'b_GWAS': 1.6879}, {'UUID': 'NDD_SMR_genes_all_update_text_1444269', 'Gene': 'LRRC37A4P', 'topRSID': 'rs11012', 'p_GWAS': 2.1076899999999998e-42, 'b_GWAS': 1.6076}, {'UUID': 'NDD_SMR_genes_all_update_text_1579415', 'Gene': 'LRRC37A4P', 'topRSID': 'rs11012', 'p_GWAS': 2.1076899999999998e-42, 'b_GWAS': 1.6076}, {'UUID': 'NDD_SMR_genes_all_update_text_1646037', 'Gene': 'LRRC37A4P', 'topRSID': 'rs11012', 'p_GWAS': 2.10769e-42, 'b_GWAS': 1.6076}]
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Q10.1547
Q10
Are there any MAF SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within MAF that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'MAF' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.346
Q10
Are there any TRIP11 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within TRIP11 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'TRIP11' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.400
Q10
Are there any NELFCD SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within NELFCD that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'NELFCD' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.1393
Q10
Are there any PAXIP1-AS1 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within PAXIP1-AS1 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'PAXIP1-AS1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.1876
Q10
Are there any MIR4321 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within MIR4321 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'MIR4321' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.199
Q10
Are there any IFNA2 SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within IFNA2 that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'IFNA2' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.1173
Q10
Are there any RPL39P SNPs that have a statistically significant association with Alzheimer's Disease?
Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there is at least 1 RPL39P SNP that are significantly associatied with Alzheimer's Disease: • rs17462136 (GWAS p-value: 6.04e-16; b-value: -0.1189)
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'RPL39P' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[{'UUID': 'NDD_SMR_genes_all_update_text_1504671', 'Gene': 'RPL39P', 'topRSID': 'rs17462136', 'p_GWAS': 6.043604e-16, 'b_GWAS': -0.1189}]
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Distinct, Multi-Filter, Order By
GWAS Significance
Q10.320
Q10
Are there any CDK2AP1 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within CDK2AP1 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'CDK2AP1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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Distinct, Multi-Filter, Order By
GWAS Significance
Q10.1002
Q10
Are there any NUPL2 SNPs that have a statistically significant association with Parkinson's Disease?
Yes, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are at least 4 NUPL2 SNPs that are significantly associatied with Parkinson's Disease: • rs858289 (GWAS p-value: 4.99e-09; b-value: -0.1035) • rs1881200 (GWAS p-value: 4.25e-08; b-value: 0.097) • rs1881201 (GWAS p-value: 3.86e-08; b-value: 0.0973) • rs1637221 (GWAS p-value: 5.19e-09; b-value: -0.1028)
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'NUPL2' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[{'UUID': 'NDD_SMR_genes_all_update_text_1593744', 'Gene': 'NUPL2', 'topRSID': 'rs858289', 'p_GWAS': 4.991429e-09, 'b_GWAS': -0.1035}, {'UUID': 'NDD_SMR_genes_all_update_text_1708094', 'Gene': 'NUPL2', 'topRSID': 'rs858289', 'p_GWAS': 4.991429e-09, 'b_GWAS': -0.1035}, {'UUID': 'NDD_SMR_genes_all_update_text_1189326', 'Gene': 'NUPL2', 'topRSID': 'rs858289', 'p_GWAS': 4.991429e-09, 'b_GWAS': -0.1035}, {'UUID': 'NDD_SMR_genes_all_update_text_1167542', 'Gene': 'NUPL2', 'topRSID': 'rs858289', 'p_GWAS': 4.991429e-09, 'b_GWAS': -0.1035}, {'UUID': 'NDD_SMR_genes_all_update_text_1431547', 'Gene': 'NUPL2', 'topRSID': 'rs1637221', 'p_GWAS': 5.191673e-09, 'b_GWAS': -0.1028}, {'UUID': 'NDD_SMR_genes_all_update_text_1557762', 'Gene': 'NUPL2', 'topRSID': 'rs1637221', 'p_GWAS': 5.191673e-09, 'b_GWAS': -0.1028}, {'UUID': 'NDD_SMR_genes_all_update_text_1260546', 'Gene': 'NUPL2', 'topRSID': 'rs1881201', 'p_GWAS': 3.859234e-08, 'b_GWAS': 0.0973}, {'UUID': 'NDD_SMR_genes_all_update_text_1237814', 'Gene': 'NUPL2', 'topRSID': 'rs1881200', 'p_GWAS': 4.247829e-08, 'b_GWAS': 0.097}]
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GWAS Significance
Q10.223
Q10
Are there any PDIA6 SNPs that have a statistically significant association with Progressive supranuclear palsy?
No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within PDIA6 that are significantly associated with Progressive supranuclear palsy.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'PDIA6' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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Distinct, Multi-Filter, Order By
GWAS Significance
Q10.1220
Q10
Are there any AC062029.1 SNPs that have a statistically significant association with Progressive supranuclear palsy?
No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within AC062029.1 that are significantly associated with Progressive supranuclear palsy.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'AC062029.1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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Distinct, Multi-Filter, Order By
GWAS Significance
Q10.103
Q10
Are there any AC009404.2 SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within AC009404.2 that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'AC009404.2' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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Distinct, Multi-Filter, Order By
GWAS Significance
Q10.1655
Q10
Are there any TF SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within TF that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'TF' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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Distinct, Multi-Filter, Order By
GWAS Significance
Q10.949
Q10
Are there any RP11-227G15.3 SNPs that have a statistically significant association with Progressive supranuclear palsy?
No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within RP11-227G15.3 that are significantly associated with Progressive supranuclear palsy.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'RP11-227G15.3' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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Distinct, Multi-Filter, Order By
GWAS Significance
Q10.1939
Q10
Are there any NKAPL SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within NKAPL that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'NKAPL' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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Distinct, Multi-Filter, Order By
GWAS Significance
Q10.1914
Q10
Are there any OXCT2 SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within OXCT2 that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'OXCT2' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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GWAS Significance
Q10.1127
Q10
Are there any SULT1A1 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within SULT1A1 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'SULT1A1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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Distinct, Multi-Filter, Order By
GWAS Significance
Q10.1052
Q10
Are there any ZFAND2B SNPs that have a statistically significant association with Progressive supranuclear palsy?
No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within ZFAND2B that are significantly associated with Progressive supranuclear palsy.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'ZFAND2B' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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Distinct, Multi-Filter, Order By
GWAS Significance
Q10.1538
Q10
Are there any AC006272.1 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within AC006272.1 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'AC006272.1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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Distinct, Multi-Filter, Order By
GWAS Significance
Q10.356
Q10
Are there any SLC41A1 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within SLC41A1 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'SLC41A1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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GWAS Significance
Q10.603
Q10
Are there any TEK SNPs that have a statistically significant association with Progressive supranuclear palsy?
No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within TEK that are significantly associated with Progressive supranuclear palsy.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'TEK' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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Distinct, Multi-Filter, Order By
GWAS Significance
Q10.1559
Q10
Are there any SHB SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within SHB that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'SHB' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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GWAS Significance
Q10.1350
Q10
Are there any C6orf10 SNPs that have a statistically significant association with Alzheimer's Disease?
Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are at least 3 C6orf10 SNPs that are significantly associatied with Alzheimer's Disease: • rs35265698 (GWAS p-value: 1.17e-16; b-value: -0.0928) • rs679242 (GWAS p-value: 4.46e-17; b-value: -0.0966) • rs601945 (GWAS p-value: 2.48e-16; b-value: -0.0918)
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'C6orf10' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[{'UUID': 'NDD_SMR_genes_all_update_text_621652', 'Gene': 'C6orf10', 'topRSID': 'rs679242', 'p_GWAS': 4.4647860000000005e-17, 'b_GWAS': -0.0966}, {'UUID': 'NDD_SMR_genes_all_update_text_621661', 'Gene': 'C6orf10', 'topRSID': 'rs35265698', 'p_GWAS': 1.174023e-16, 'b_GWAS': -0.0928}, {'UUID': 'NDD_SMR_genes_all_update_text_621651', 'Gene': 'C6orf10', 'topRSID': 'rs35265698', 'p_GWAS': 1.174023e-16, 'b_GWAS': -0.0928}, {'UUID': 'NDD_SMR_genes_all_update_text_621662', 'Gene': 'C6orf10', 'topRSID': 'rs35265698', 'p_GWAS': 1.174023e-16, 'b_GWAS': -0.0928}, {'UUID': 'NDD_SMR_genes_all_update_text_621650', 'Gene': 'C6orf10', 'topRSID': 'rs35265698', 'p_GWAS': 1.174023e-16, 'b_GWAS': -0.0928}, {'UUID': 'NDD_SMR_genes_all_update_text_621660', 'Gene': 'C6orf10', 'topRSID': 'rs35265698', 'p_GWAS': 1.174023e-16, 'b_GWAS': -0.0928}, {'UUID': 'NDD_SMR_genes_all_update_text_621653', 'Gene': 'C6orf10', 'topRSID': 'rs35265698', 'p_GWAS': 1.174023e-16, 'b_GWAS': -0.0928}, {'UUID': 'NDD_SMR_genes_all_update_text_621656', 'Gene': 'C6orf10', 'topRSID': 'rs35265698', 'p_GWAS': 1.174023e-16, 'b_GWAS': -0.0928}, {'UUID': 'NDD_SMR_genes_all_update_text_621654', 'Gene': 'C6orf10', 'topRSID': 'rs601945', 'p_GWAS': 2.476343e-16, 'b_GWAS': -0.0918}, {'UUID': 'NDD_SMR_genes_all_update_text_621657', 'Gene': 'C6orf10', 'topRSID': 'rs601945', 'p_GWAS': 2.476343e-16, 'b_GWAS': -0.0918}, {'UUID': 'NDD_SMR_genes_all_update_text_621658', 'Gene': 'C6orf10', 'topRSID': 'rs601945', 'p_GWAS': 2.476343e-16, 'b_GWAS': -0.0918}, {'UUID': 'NDD_SMR_genes_all_update_text_621659', 'Gene': 'C6orf10', 'topRSID': 'rs601945', 'p_GWAS': 2.476343e-16, 'b_GWAS': -0.0918}, {'UUID': 'NDD_SMR_genes_all_update_text_621655', 'Gene': 'C6orf10', 'topRSID': 'rs601945', 'p_GWAS': 2.476343e-16, 'b_GWAS': -0.0918}]
refined
Distinct, Multi-Filter, Order By
GWAS Significance
Q10.1359
Q10
Are there any AC007401.2 SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within AC007401.2 that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'AC007401.2' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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Distinct, Multi-Filter, Order By
GWAS Significance
Q10.947
Q10
Are there any HMG20A SNPs that have a statistically significant association with Progressive supranuclear palsy?
No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within HMG20A that are significantly associated with Progressive supranuclear palsy.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'HMG20A' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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Distinct, Multi-Filter, Order By
GWAS Significance
Q10.348
Q10
Are there any LMTK3 SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within LMTK3 that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'LMTK3' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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GWAS Significance
Q10.606
Q10
Are there any OR10AG1 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within OR10AG1 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'OR10AG1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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Distinct, Multi-Filter, Order By
GWAS Significance
Q10.719
Q10
Are there any CYB5B SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within CYB5B that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'CYB5B' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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GWAS Significance
Q10.118
Q10
Are there any CTD-3065J16.9 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within CTD-3065J16.9 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'CTD-3065J16.9' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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GWAS Significance
Q10.617
Q10
Are there any SOST SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within SOST that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'SOST' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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Distinct, Multi-Filter, Order By
GWAS Significance
Q10.1013
Q10
Are there any AC064853.3 SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within AC064853.3 that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'AC064853.3' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
refined
Distinct, Multi-Filter, Order By
GWAS Significance
Q10.1265
Q10
Are there any SYCE2 SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within SYCE2 that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'SYCE2' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
refined
Distinct, Multi-Filter, Order By
GWAS Significance
Q10.1489
Q10
Are there any KTN1-AS1 SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within KTN1-AS1 that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'KTN1-AS1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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GWAS Significance
Q10.489
Q10
Are there any IGLVI-70 SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within IGLVI-70 that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'IGLVI-70' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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Distinct, Multi-Filter, Order By
GWAS Significance
Q10.1711
Q10
Are there any NMBR SNPs that have a statistically significant association with Progressive supranuclear palsy?
No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within NMBR that are significantly associated with Progressive supranuclear palsy.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'NMBR' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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GWAS Significance
Q10.787
Q10
Are there any ZBP1 SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within ZBP1 that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'ZBP1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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Distinct, Multi-Filter, Order By
GWAS Significance
Q10.881
Q10
Are there any GNB2L1 SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within GNB2L1 that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'GNB2L1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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Distinct, Multi-Filter, Order By
GWAS Significance
Q10.1555
Q10
Are there any EPDR1 SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within EPDR1 that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'EPDR1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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GWAS Significance
Q10.567
Q10
Are there any OR7M1P SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within OR7M1P that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'OR7M1P' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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Distinct, Multi-Filter, Order By
GWAS Significance
Q10.254
Q10
Are there any TPM3P9 SNPs that have a statistically significant association with Progressive supranuclear palsy?
No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within TPM3P9 that are significantly associated with Progressive supranuclear palsy.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'TPM3P9' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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GWAS Significance
Q10.242
Q10
Are there any SNORD12B SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within SNORD12B that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'SNORD12B' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.176
Q10
Are there any LILRA1 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within LILRA1 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'LILRA1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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GWAS Significance
Q10.824
Q10
Are there any AGFG2 SNPs that have a statistically significant association with Alzheimer's Disease?
Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there is at least 1 AGFG2 SNP that are significantly associatied with Alzheimer's Disease: • rs2734897 (GWAS p-value: 9.83e-12; b-value: 0.0606)
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'AGFG2' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[{'UUID': 'NDD_SMR_genes_all_update_text_1687938', 'Gene': 'AGFG2', 'topRSID': 'rs2734897', 'p_GWAS': 9.828715e-12, 'b_GWAS': 0.0606}]
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GWAS Significance
Q10.983
Q10
Are there any NCOR1 SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within NCOR1 that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'NCOR1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.1476
Q10
Are there any ITGA9 SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within ITGA9 that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'ITGA9' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.1262
Q10
Are there any ZNF649 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within ZNF649 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'ZNF649' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.1280
Q10
Are there any RP11-254F7.2 SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within RP11-254F7.2 that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'RP11-254F7.2' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.751
Q10
Are there any BAG1 SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within BAG1 that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'BAG1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.561
Q10
Are there any RP11-799M12.2 SNPs that have a statistically significant association with Progressive supranuclear palsy?
No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within RP11-799M12.2 that are significantly associated with Progressive supranuclear palsy.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'RP11-799M12.2' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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GWAS Significance
Q10.81
Q10
Are there any CCDC189 SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within CCDC189 that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'CCDC189' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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GWAS Significance
Q10.1042
Q10
Are there any DDX11 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within DDX11 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'DDX11' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.1314
Q10
Are there any RP11-1055B8.4 SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within RP11-1055B8.4 that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'RP11-1055B8.4' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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GWAS Significance
Q10.33
Q10
Are there any SLFN14 SNPs that have a statistically significant association with Progressive supranuclear palsy?
No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within SLFN14 that are significantly associated with Progressive supranuclear palsy.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'SLFN14' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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GWAS Significance
Q10.1739
Q10
Are there any CSTP1 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within CSTP1 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'CSTP1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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GWAS Significance
Q10.358
Q10
Are there any CCDC57 SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within CCDC57 that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'CCDC57' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.1077
Q10
Are there any PPM1F SNPs that have a statistically significant association with Progressive supranuclear palsy?
No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within PPM1F that are significantly associated with Progressive supranuclear palsy.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'PPM1F' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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GWAS Significance
Q10.1692
Q10
Are there any ADAM10 SNPs that have a statistically significant association with Alzheimer's Disease?
Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are at least 2 ADAM10 SNPs that are significantly associatied with Alzheimer's Disease: • rs2250583 (GWAS p-value: 7.74e-11; b-value: -0.0579) • rs6494037 (GWAS p-value: 3.81e-11; b-value: -0.0595)
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'ADAM10' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[{'UUID': 'NDD_SMR_genes_all_update_text_646470', 'Gene': 'ADAM10', 'topRSID': 'rs6494037', 'p_GWAS': 3.81446e-11, 'b_GWAS': -0.0595}, {'UUID': 'NDD_SMR_genes_all_update_text_105563', 'Gene': 'ADAM10', 'topRSID': 'rs2250583', 'p_GWAS': 7.737463e-11, 'b_GWAS': -0.0579}]
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GWAS Significance
Q10.127
Q10
Are there any ABCG4 SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within ABCG4 that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'ABCG4' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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GWAS Significance
Q10.1031
Q10
Are there any RP11-529H20.6 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within RP11-529H20.6 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'RP11-529H20.6' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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GWAS Significance
Q10.399
Q10
Are there any MAU2 SNPs that have a statistically significant association with Progressive supranuclear palsy?
No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within MAU2 that are significantly associated with Progressive supranuclear palsy.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'MAU2' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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Q10.444
Q10
Are there any BDNF-AS SNPs that have a statistically significant association with Progressive supranuclear palsy?
No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within BDNF-AS that are significantly associated with Progressive supranuclear palsy.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'BDNF-AS' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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GWAS Significance
Q10.166
Q10
Are there any RP11-798G7.8 SNPs that have a statistically significant association with Alzheimer's Disease?
Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are at least 2 RP11-798G7.8 SNPs that are significantly associatied with Alzheimer's Disease: • rs62055937 (GWAS p-value: 3.01e-08; b-value: -0.0543) • rs16940672 (GWAS p-value: 4.78e-08; b-value: -0.0535)
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'RP11-798G7.8' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[{'UUID': 'NDD_SMR_genes_all_update_text_1343147', 'Gene': 'RP11-798G7.8', 'topRSID': 'rs62055937', 'p_GWAS': 3.010649e-08, 'b_GWAS': -0.0543}, {'UUID': 'NDD_SMR_genes_all_update_text_1610858', 'Gene': 'RP11-798G7.8', 'topRSID': 'rs16940672', 'p_GWAS': 4.783287e-08, 'b_GWAS': -0.0535}]
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Q10.206
Q10
Are there any OR2AT4 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within OR2AT4 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'OR2AT4' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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GWAS Significance
Q10.1571
Q10
Are there any FCER1G SNPs that have a statistically significant association with Alzheimer's Disease?
Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are at least 2 FCER1G SNPs that are significantly associatied with Alzheimer's Disease: • rs2070902 (GWAS p-value: 1.11e-08; b-value: 0.0537) • rs2070901 (GWAS p-value: 1.01e-08; b-value: 0.0527)
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'FCER1G' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[{'UUID': 'NDD_SMR_genes_all_update_text_1337987', 'Gene': 'FCER1G', 'topRSID': 'rs2070901', 'p_GWAS': 1.014655e-08, 'b_GWAS': -0.0527}, {'UUID': 'NDD_SMR_genes_all_update_text_1490908', 'Gene': 'FCER1G', 'topRSID': 'rs2070901', 'p_GWAS': 1.014655e-08, 'b_GWAS': -0.0527}, {'UUID': 'NDD_SMR_genes_all_update_text_40017', 'Gene': 'FCER1G', 'topRSID': 'rs2070901', 'p_GWAS': 1.014655e-08, 'b_GWAS': 0.0527}, {'UUID': 'NDD_SMR_genes_all_update_text_1647531', 'Gene': 'FCER1G', 'topRSID': 'rs2070901', 'p_GWAS': 1.014655e-08, 'b_GWAS': -0.0527}, {'UUID': 'NDD_SMR_genes_all_update_text_40016', 'Gene': 'FCER1G', 'topRSID': 'rs2070902', 'p_GWAS': 1.111545e-08, 'b_GWAS': 0.0537}, {'UUID': 'NDD_SMR_genes_all_update_text_1105080', 'Gene': 'FCER1G', 'topRSID': 'rs2070902', 'p_GWAS': 1.111545e-08, 'b_GWAS': 0.0537}]
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GWAS Significance
Q10.1641
Q10
Are there any TUSC2 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within TUSC2 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'TUSC2' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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GWAS Significance
Q10.1565
Q10
Are there any ZKSCAN3 SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within ZKSCAN3 that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'ZKSCAN3' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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GWAS Significance
Q10.491
Q10
Are there any NOD2 SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within NOD2 that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'NOD2' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.1966
Q10
Are there any INO80E SNPs that have a statistically significant association with Alzheimer's Disease?
Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are at least 9 INO80E SNPs that are significantly associatied with Alzheimer's Disease: • rs9932196 (GWAS p-value: 1.08e-09; b-value: 0.05) • rs10871451 (GWAS p-value: 1.16e-09; b-value: 0.0499) • rs12928610 (GWAS p-value: 1.56e-08; b-value: 0.0458) • rs4788199 (GWAS p-value: 1.81e-08; b-value: 0.0456) • rs9925915 (GWAS p-value: 8.56e-10; b-value: 0.0503) • rs4788204 (GWAS p-value: 9.98e-10; b-value: -0.0501) • rs8054556 (GWAS p-value: 2.13e-09; b-value: -0.0491) • rs4787491 (GWAS p-value: 6.53e-09; b-value: -0.047) • rs7193532 (GWAS p-value: 1.35e-09; b-value: -0.0497)
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'INO80E' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[{'UUID': 'NDD_SMR_genes_all_update_text_1501441', 'Gene': 'INO80E', 'topRSID': 'rs9925915', 'p_GWAS': 8.561768e-10, 'b_GWAS': -0.0503}, {'UUID': 'NDD_SMR_genes_all_update_text_1111646', 'Gene': 'INO80E', 'topRSID': 'rs9925915', 'p_GWAS': 8.561768e-10, 'b_GWAS': 0.0503}, {'UUID': 'NDD_SMR_genes_all_update_text_1174356', 'Gene': 'INO80E', 'topRSID': 'rs4788204', 'p_GWAS': 9.978352e-10, 'b_GWAS': -0.0501}, {'UUID': 'NDD_SMR_genes_all_update_text_2876', 'Gene': 'INO80E', 'topRSID': 'rs9932196', 'p_GWAS': 1.07699e-09, 'b_GWAS': 0.05}, {'UUID': 'NDD_SMR_genes_all_update_text_109450', 'Gene': 'INO80E', 'topRSID': 'rs10871451', 'p_GWAS': 1.162256e-09, 'b_GWAS': 0.0499}, {'UUID': 'NDD_SMR_genes_all_update_text_1610394', 'Gene': 'INO80E', 'topRSID': 'rs10871451', 'p_GWAS': 1.162256e-09, 'b_GWAS': 0.0499}, {'UUID': 'NDD_SMR_genes_all_update_text_1342779', 'Gene': 'INO80E', 'topRSID': 'rs7193532', 'p_GWAS': 1.352984e-09, 'b_GWAS': -0.0497}, {'UUID': 'NDD_SMR_genes_all_update_text_1652082', 'Gene': 'INO80E', 'topRSID': 'rs8054556', 'p_GWAS': 2.12692e-09, 'b_GWAS': -0.0491}, {'UUID': 'NDD_SMR_genes_all_update_text_1689746', 'Gene': 'INO80E', 'topRSID': 'rs8054556', 'p_GWAS': 2.12692e-09, 'b_GWAS': -0.0491}, {'UUID': 'NDD_SMR_genes_all_update_text_1396161', 'Gene': 'INO80E', 'topRSID': 'rs8054556', 'p_GWAS': 2.12692e-09, 'b_GWAS': -0.0491}, {'UUID': 'NDD_SMR_genes_all_update_text_1246851', 'Gene': 'INO80E', 'topRSID': 'rs8054556', 'p_GWAS': 2.12692e-09, 'b_GWAS': -0.0491}, {'UUID': 'NDD_SMR_genes_all_update_text_1291219', 'Gene': 'INO80E', 'topRSID': 'rs4787491', 'p_GWAS': 6.534543e-09, 'b_GWAS': -0.047}, {'UUID': 'NDD_SMR_genes_all_update_text_1466508', 'Gene': 'INO80E', 'topRSID': 'rs4787491', 'p_GWAS': 6.534543e-09, 'b_GWAS': -0.047}, {'UUID': 'NDD_SMR_genes_all_update_text_109451', 'Gene': 'INO80E', 'topRSID': 'rs12928610', 'p_GWAS': 1.564636e-08, 'b_GWAS': 0.0458}, {'UUID': 'NDD_SMR_genes_all_update_text_577415', 'Gene': 'INO80E', 'topRSID': 'rs4788199', 'p_GWAS': 1.80597e-08, 'b_GWAS': 0.0456}]
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GWAS Significance
Q10.1800
Q10
Are there any CTD-2020K17.1 SNPs that have a statistically significant association with Alzheimer's Disease?
Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there is at least 1 CTD-2020K17.1 SNP that are significantly associatied with Alzheimer's Disease: • rs62063276 (GWAS p-value: 3.80e-08; b-value: -0.0539)
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'CTD-2020K17.1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[{'UUID': 'NDD_SMR_genes_all_update_text_1690032', 'Gene': 'CTD-2020K17.1', 'topRSID': 'rs62063276', 'p_GWAS': 3.797912e-08, 'b_GWAS': -0.0539}]
refined
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Q10.1330
Q10
Are there any CCND3 SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within CCND3 that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'CCND3' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.285
Q10
Are there any CARF SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within CARF that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'CARF' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.1375
Q10
Are there any HPS3 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within HPS3 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'HPS3' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.221
Q10
Are there any AL928768.3 SNPs that have a statistically significant association with Alzheimer's Disease?
Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there is at least 1 AL928768.3 SNP that are significantly associatied with Alzheimer's Disease: • rs8009444 (GWAS p-value: 2.33e-09; b-value: 0.0663)
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'AL928768.3' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[{'UUID': 'NDD_SMR_genes_all_update_text_1500534', 'Gene': 'AL928768.3', 'topRSID': 'rs8009444', 'p_GWAS': 2.329685e-09, 'b_GWAS': 0.0663}]
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Q10.1931
Q10
Are there any OR5T2 SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within OR5T2 that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'OR5T2' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.888
Q10
Are there any RP11-122A3.2 SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within RP11-122A3.2 that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'RP11-122A3.2' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.1623
Q10
Are there any CTC-550B14.7 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within CTC-550B14.7 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'CTC-550B14.7' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.701
Q10
Are there any NSFP1 SNPs that have a statistically significant association with Progressive supranuclear palsy?
Yes, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are at least 2 NSFP1 SNPs that are significantly associatied with Progressive supranuclear palsy: • rs4792831 (GWAS p-value: 1.06e-15; b-value: -0.5293) • rs17692129 (GWAS p-value: 5.79e-22; b-value: -0.5568)
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'NSFP1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[{'UUID': 'NDD_SMR_genes_all_update_text_1579428', 'Gene': 'NSFP1', 'topRSID': 'rs17692129', 'p_GWAS': 5.788764e-22, 'b_GWAS': -0.5568}, {'UUID': 'NDD_SMR_genes_all_update_text_1596828', 'Gene': 'NSFP1', 'topRSID': 'rs17692129', 'p_GWAS': 5.788764e-22, 'b_GWAS': -0.5568}, {'UUID': 'NDD_SMR_genes_all_update_text_1336297', 'Gene': 'NSFP1', 'topRSID': 'rs4792831', 'p_GWAS': 1.060064e-15, 'b_GWAS': -0.5293}, {'UUID': 'NDD_SMR_genes_all_update_text_1732401', 'Gene': 'NSFP1', 'topRSID': 'rs4792831', 'p_GWAS': 1.060064e-15, 'b_GWAS': -0.5293}, {'UUID': 'NDD_SMR_genes_all_update_text_1489543', 'Gene': 'NSFP1', 'topRSID': 'rs4792831', 'p_GWAS': 1.060064e-15, 'b_GWAS': -0.5293}, {'UUID': 'NDD_SMR_genes_all_update_text_1388486', 'Gene': 'NSFP1', 'topRSID': 'rs4792831', 'p_GWAS': 1.060064e-15, 'b_GWAS': -0.5293}, {'UUID': 'NDD_SMR_genes_all_update_text_1684940', 'Gene': 'NSFP1', 'topRSID': 'rs4792831', 'p_GWAS': 1.060064e-15, 'b_GWAS': -0.5293}, {'UUID': 'NDD_SMR_genes_all_update_text_1714162', 'Gene': 'NSFP1', 'topRSID': 'rs4792831', 'p_GWAS': 1.060064e-15, 'b_GWAS': -0.5293}, {'UUID': 'NDD_SMR_genes_all_update_text_1464423', 'Gene': 'NSFP1', 'topRSID': 'rs4792831', 'p_GWAS': 1.060064e-15, 'b_GWAS': -0.5293}, {'UUID': 'NDD_SMR_genes_all_update_text_1283709', 'Gene': 'NSFP1', 'topRSID': 'rs4792831', 'p_GWAS': 1.060064e-15, 'b_GWAS': -0.5293}, {'UUID': 'NDD_SMR_genes_all_update_text_1194222', 'Gene': 'NSFP1', 'topRSID': 'rs4792831', 'p_GWAS': 1.060064e-15, 'b_GWAS': -0.5293}, {'UUID': 'NDD_SMR_genes_all_update_text_1604718', 'Gene': 'NSFP1', 'topRSID': 'rs4792831', 'p_GWAS': 1.060064e-15, 'b_GWAS': -0.5293}, {'UUID': 'NDD_SMR_genes_all_update_text_1170878', 'Gene': 'NSFP1', 'topRSID': 'rs4792831', 'p_GWAS': 1.060064e-15, 'b_GWAS': -0.5293}, {'UUID': 'NDD_SMR_genes_all_update_text_1478192', 'Gene': 'NSFP1', 'topRSID': 'rs4792831', 'p_GWAS': 1.060064e-15, 'b_GWAS': -0.5293}, {'UUID': 'NDD_SMR_genes_all_update_text_1375935', 'Gene': 'NSFP1', 'topRSID': 'rs4792831', 'p_GWAS': 1.060064e-15, 'b_GWAS': -0.5293}, {'UUID': 'NDD_SMR_genes_all_update_text_1264988', 'Gene': 'NSFP1', 'topRSID': 'rs4792831', 'p_GWAS': 1.060064e-15, 'b_GWAS': -0.5293}]
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GWAS Significance
Q10.61
Q10
Are there any AC005082.1 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within AC005082.1 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'AC005082.1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.843
Q10
Are there any SFXN4 SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within SFXN4 that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'SFXN4' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.1356
Q10
Are there any LINC01102 SNPs that have a statistically significant association with Progressive supranuclear palsy?
No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within LINC01102 that are significantly associated with Progressive supranuclear palsy.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'LINC01102' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.76
Q10
Are there any OR10H2 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within OR10H2 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'OR10H2' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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GWAS Significance
Q10.165
Q10
Are there any NRP2 SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within NRP2 that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'NRP2' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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