uuid stringlengths 4 8 | template_uuid stringclasses 40 values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 138 627 | execution_results stringlengths 2 1.14M | query_type stringclasses 2 values | sql_category stringclasses 26 values | bio_category stringclasses 14 values |
|---|---|---|---|---|---|---|---|---|
Q10.1946 | Q10 | Are there any DMBX1 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within DMBX1 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'DMBX1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1581 | Q10 | Are there any CTF1 SNPs that have a statistically significant association with Parkinson's Disease? | Yes, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there is at least 1 CTF1 SNP that are significantly associatied with Parkinson's Disease:
• rs11640534 (GWAS p-value: 2.43e-10; b-value: -0.1165) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'CTF1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_974660', 'Gene': 'CTF1', 'topRSID': 'rs11640534', 'p_GWAS': 2.42755e-10, 'b_GWAS': -0.1165}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1490 | Q10 | Are there any C17orf76-AS1 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within C17orf76-AS1 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'C17orf76-AS1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.410 | Q10 | Are there any RNU6-2 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within RNU6-2 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'RNU6-2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1728 | Q10 | Are there any YIF1A SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within YIF1A that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'YIF1A' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1298 | Q10 | Are there any ENTR1 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within ENTR1 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'ENTR1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1665 | Q10 | Are there any PRMT6 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within PRMT6 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'PRMT6' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.107 | Q10 | Are there any PITRM1-AS1 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within PITRM1-AS1 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'PITRM1-AS1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.695 | Q10 | Are there any FAM117A SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within FAM117A that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'FAM117A' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1305 | Q10 | Are there any THSD7A SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within THSD7A that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'THSD7A' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.833 | Q10 | Are there any STX7 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within STX7 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'STX7' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.64 | Q10 | Are there any CNFN SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within CNFN that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'CNFN' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.859 | Q10 | Are there any SKAP2 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within SKAP2 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'SKAP2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1355 | Q10 | Are there any CTD-3214H19.6 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within CTD-3214H19.6 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'CTD-3214H19.6' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.226 | Q10 | Are there any EML6 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within EML6 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'EML6' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.148 | Q10 | Are there any VPS37A SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within VPS37A that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'VPS37A' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1097 | Q10 | Are there any FAM215B SNPs that have a statistically significant association with Parkinson's Disease? | Yes, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are at least 2 FAM215B SNPs that are significantly associatied with Parkinson's Disease:
• rs9896243 (GWAS p-value: 3.17e-18; b-value: -0.2185)
• rs55974014 (GWAS p-value: 8.84e-21; b-value: -0.2571) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'FAM215B' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1710359', 'Gene': 'FAM215B', 'topRSID': 'rs55974014', 'p_GWAS': 8.840428e-21, 'b_GWAS': -0.2571}, {'UUID': 'NDD_SMR_genes_all_update_text_1191181', 'Gene': 'FAM215B', 'topRSID': 'rs9896243', 'p_GWAS': 3.170731e-18, 'b_GWAS': -0.2185}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.379 | Q10 | Are there any TRBJ2-2 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within TRBJ2-2 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'TRBJ2-2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1422 | Q10 | Are there any AC006160.5 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within AC006160.5 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'AC006160.5' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1152 | Q10 | Are there any CEACAM19 SNPs that have a statistically significant association with Alzheimer's Disease? | Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are at least 2 CEACAM19 SNPs that are significantly associatied with Alzheimer's Disease:
• rs56261258 (GWAS p-value: 4.68e-19; b-value: -0.1222)
• rs714948 (GWAS p-value: 7.11e-18; b-value: -0.118) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'CEACAM19' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_4008', 'Gene': 'CEACAM19', 'topRSID': 'rs56261258', 'p_GWAS': 4.675190999999999e-19, 'b_GWAS': -0.1222}, {'UUID': 'NDD_SMR_genes_all_update_text_1203796', 'Gene': 'CEACAM19', 'topRSID': 'rs56261258', 'p_GWAS': 4.675190999999999e-19, 'b_GWAS': 0.1222}, {'UUID': 'NDD_SMR_genes_all_update_text_1268424', 'Gene': 'CEACAM19', 'topRSID': 'rs56261258', 'p_GWAS': 4.675190999999999e-19, 'b_GWAS': -0.1222}, {'UUID': 'NDD_SMR_genes_all_update_text_1378751', 'Gene': 'CEACAM19', 'topRSID': 'rs56261258', 'p_GWAS': 4.675190999999999e-19, 'b_GWAS': -0.1222}, {'UUID': 'NDD_SMR_genes_all_update_text_1157464', 'Gene': 'CEACAM19', 'topRSID': 'rs714948', 'p_GWAS': 7.108701000000001e-18, 'b_GWAS': -0.118}, {'UUID': 'NDD_SMR_genes_all_update_text_1690531', 'Gene': 'CEACAM19', 'topRSID': 'rs714948', 'p_GWAS': 7.108701000000001e-18, 'b_GWAS': -0.118}, {'UUID': 'NDD_SMR_genes_all_update_text_1247434', 'Gene': 'CEACAM19', 'topRSID': 'rs714948', 'p_GWAS': 7.108701000000001e-18, 'b_GWAS': -0.118}, {'UUID': 'NDD_SMR_genes_all_update_text_1454558', 'Gene': 'CEACAM19', 'topRSID': 'rs714948', 'p_GWAS': 7.108701000000001e-18, 'b_GWAS': -0.118}, {'UUID': 'NDD_SMR_genes_all_update_text_1480339', 'Gene': 'CEACAM19', 'topRSID': 'rs714948', 'p_GWAS': 7.108701000000001e-18, 'b_GWAS': -0.118}, {'UUID': 'NDD_SMR_genes_all_update_text_1717663', 'Gene': 'CEACAM19', 'topRSID': 'rs714948', 'p_GWAS': 7.108701000000001e-18, 'b_GWAS': -0.118}, {'UUID': 'NDD_SMR_genes_all_update_text_1397644', 'Gene': 'CEACAM19', 'topRSID': 'rs714948', 'p_GWAS': 7.108701000000001e-18, 'b_GWAS': 0.118}, {'UUID': 'NDD_SMR_genes_all_update_text_1175009', 'Gene': 'CEACAM19', 'topRSID': 'rs714948', 'p_GWAS': 7.108701000000001e-18, 'b_GWAS': -0.118}, {'UUID': 'NDD_SMR_genes_all_update_text_1108029', 'Gene': 'CEACAM19', 'topRSID': 'rs714948', 'p_GWAS': 7.108701000000001e-18, 'b_GWAS': -0.118}, {'UUID': 'NDD_SMR_genes_all_update_text_1611534', 'Gene': 'CEACAM19', 'topRSID': 'rs714948', 'p_GWAS': 7.108701000000001e-18, 'b_GWAS': -0.118}, {'UUID': 'NDD_SMR_genes_all_update_text_1598392', 'Gene': 'CEACAM19', 'topRSID': 'rs714948', 'p_GWAS': 7.108701000000001e-18, 'b_GWAS': -0.118}, {'UUID': 'NDD_SMR_genes_all_update_text_1653156', 'Gene': 'CEACAM19', 'topRSID': 'rs714948', 'p_GWAS': 7.108701000000001e-18, 'b_GWAS': -0.118}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1828 | Q10 | Are there any AC007292.6 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within AC007292.6 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'AC007292.6' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1496 | Q10 | Are there any TGM2 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within TGM2 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'TGM2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1602 | Q10 | Are there any VPS13C SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within VPS13C that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'VPS13C' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1759 | Q10 | Are there any AP000351.3 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within AP000351.3 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'AP000351.3' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.10 | Q10 | Are there any POMT2 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within POMT2 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'POMT2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.455 | Q10 | Are there any RP11-416I2.1 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within RP11-416I2.1 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'RP11-416I2.1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.715 | Q10 | Are there any PILRA SNPs that have a statistically significant association with Alzheimer's Disease? | Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there is at least 1 PILRA SNP that are significantly associatied with Alzheimer's Disease:
• rs2005763 (GWAS p-value: 8.92e-10; b-value: -0.0576) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'PILRA' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1495807', 'Gene': 'PILRA', 'topRSID': 'rs2005763', 'p_GWAS': 8.918114e-10, 'b_GWAS': -0.0576}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.258 | Q10 | Are there any ZNF404 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within ZNF404 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'ZNF404' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.889 | Q10 | Are there any ZNF470 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within ZNF470 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'ZNF470' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.395 | Q10 | Are there any ANKRD26P3 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within ANKRD26P3 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'ANKRD26P3' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.916 | Q10 | Are there any C15orf17 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within C15orf17 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'C15orf17' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.932 | Q10 | Are there any STH SNPs that have a statistically significant association with Parkinson's Disease? | Yes, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there is at least 1 STH SNP that are significantly associatied with Parkinson's Disease:
• rs11079718 (GWAS p-value: 1.36e-20; b-value: 0.2512) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'STH' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1147255', 'Gene': 'STH', 'topRSID': 'rs11079718', 'p_GWAS': 1.356367e-20, 'b_GWAS': 0.2512}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1704 | Q10 | Are there any RP11-214N9.1 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within RP11-214N9.1 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'RP11-214N9.1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1231 | Q10 | Are there any UNC5D SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within UNC5D that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'UNC5D' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.466 | Q10 | Are there any TAF4B SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within TAF4B that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'TAF4B' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1967 | Q10 | Are there any C6orf229 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within C6orf229 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'C6orf229' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1178 | Q10 | Are there any FGF3 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within FGF3 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'FGF3' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.967 | Q10 | Are there any RP11-84E24.3 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within RP11-84E24.3 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'RP11-84E24.3' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.507 | Q10 | Are there any DPEP2 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within DPEP2 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'DPEP2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.746 | Q10 | Are there any IGSF9B SNPs that have a statistically significant association with Parkinson's Disease? | Yes, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are at least 2 IGSF9B SNPs that are significantly associatied with Parkinson's Disease:
• rs167915 (GWAS p-value: 4.39e-08; b-value: -0.0969)
• rs564123 (GWAS p-value: 4.84e-08; b-value: -0.0955) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'IGSF9B' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_470341', 'Gene': 'IGSF9B', 'topRSID': 'rs167915', 'p_GWAS': 4.385597e-08, 'b_GWAS': -0.0969}, {'UUID': 'NDD_SMR_genes_all_update_text_1433772', 'Gene': 'IGSF9B', 'topRSID': 'rs564123', 'p_GWAS': 4.838571e-08, 'b_GWAS': -0.0955}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1851 | Q10 | Are there any HSBP1L1 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within HSBP1L1 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'HSBP1L1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.875 | Q10 | Are there any TSC22D4 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within TSC22D4 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'TSC22D4' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.738 | Q10 | Are there any AQR SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within AQR that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'AQR' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.545 | Q10 | Are there any WAC SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within WAC that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'WAC' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1211 | Q10 | Are there any ABHD17A SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within ABHD17A that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'ABHD17A' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.704 | Q10 | Are there any AC003682.17 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within AC003682.17 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'AC003682.17' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1394 | Q10 | Are there any PRB2 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within PRB2 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'PRB2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1783 | Q10 | Are there any RP5-894D12.5 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within RP5-894D12.5 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'RP5-894D12.5' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1155 | Q10 | Are there any RP11-182N22.8 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within RP11-182N22.8 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'RP11-182N22.8' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1040 | Q10 | Are there any CDH24 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within CDH24 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'CDH24' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.378 | Q10 | Are there any RP3-462E2.3 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within RP3-462E2.3 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'RP3-462E2.3' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.674 | Q10 | Are there any LDLRAD4 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within LDLRAD4 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'LDLRAD4' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1527 | Q10 | Are there any LA16c-381G6.1 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within LA16c-381G6.1 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'LA16c-381G6.1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.362 | Q10 | Are there any DOC2A SNPs that have a statistically significant association with Alzheimer's Disease? | Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there is at least 18 DOC2A SNP that are significantly associatied with Alzheimer's Disease:
• rs11642612 (GWAS p-value: 2.62e-11; b-value: -0.056)
• rs12325400 (GWAS p-value: 2.84e-11; b-value: 0.0559)
• rs12921753 (GWAS p-value: 2.84e-11; b-value: -0.0559)
• rs12444108 (GWAS p-value: 3.34e-11; b-value: 0.0557)
• rs11642740 (GWAS p-value: 3.62e-11; b-value: -0.0556)
• rs12598856 (GWAS p-value: 3.92e-11; b-value: 0.0555)
• rs7191849 (GWAS p-value: 2.60e-10; b-value: 0.0512)
• rs3814878 (GWAS p-value: 3.05e-10; b-value: 0.051)
• rs4788213 (GWAS p-value: 3.30e-10; b-value: -0.0509)
• rs12596543 (GWAS p-value: 3.87e-10; b-value: -0.0507) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'DOC2A' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_577425', 'Gene': 'DOC2A', 'topRSID': 'rs11642612', 'p_GWAS': 2.616785e-11, 'b_GWAS': -0.056}, {'UUID': 'NDD_SMR_genes_all_update_text_109456', 'Gene': 'DOC2A', 'topRSID': 'rs12325400', 'p_GWAS': 2.83759e-11, 'b_GWAS': 0.0559}, {'UUID': 'NDD_SMR_genes_all_update_text_577418', 'Gene': 'DOC2A', 'topRSID': 'rs12921753', 'p_GWAS': 2.83759e-11, 'b_GWAS': -0.0559}, {'UUID': 'NDD_SMR_genes_all_update_text_109460', 'Gene': 'DOC2A', 'topRSID': 'rs12444108', 'p_GWAS': 3.335278e-11, 'b_GWAS': 0.0557}, {'UUID': 'NDD_SMR_genes_all_update_text_577420', 'Gene': 'DOC2A', 'topRSID': 'rs11642740', 'p_GWAS': 3.615204e-11, 'b_GWAS': -0.0556}, {'UUID': 'NDD_SMR_genes_all_update_text_109461', 'Gene': 'DOC2A', 'topRSID': 'rs12598856', 'p_GWAS': 3.918079e-11, 'b_GWAS': 0.0555}, {'UUID': 'NDD_SMR_genes_all_update_text_577423', 'Gene': 'DOC2A', 'topRSID': 'rs7191849', 'p_GWAS': 2.598968e-10, 'b_GWAS': -0.0512}, {'UUID': 'NDD_SMR_genes_all_update_text_109455', 'Gene': 'DOC2A', 'topRSID': 'rs7191849', 'p_GWAS': 2.598968e-10, 'b_GWAS': 0.0512}, {'UUID': 'NDD_SMR_genes_all_update_text_109459', 'Gene': 'DOC2A', 'topRSID': 'rs3814878', 'p_GWAS': 3.048414e-10, 'b_GWAS': 0.051}, {'UUID': 'NDD_SMR_genes_all_update_text_577427', 'Gene': 'DOC2A', 'topRSID': 'rs4788213', 'p_GWAS': 3.300756e-10, 'b_GWAS': -0.0509}, {'UUID': 'NDD_SMR_genes_all_update_text_577419', 'Gene': 'DOC2A', 'topRSID': 'rs12596543', 'p_GWAS': 3.868104e-10, 'b_GWAS': -0.0507}, {'UUID': 'NDD_SMR_genes_all_update_text_577421', 'Gene': 'DOC2A', 'topRSID': 'rs12933575', 'p_GWAS': 4.901621e-10, 'b_GWAS': -0.0504}, {'UUID': 'NDD_SMR_genes_all_update_text_109453', 'Gene': 'DOC2A', 'topRSID': 'rs3814880', 'p_GWAS': 9.978352e-10, 'b_GWAS': 0.0501}, {'UUID': 'NDD_SMR_genes_all_update_text_109454', 'Gene': 'DOC2A', 'topRSID': 'rs10871451', 'p_GWAS': 1.162256e-09, 'b_GWAS': 0.0499}, {'UUID': 'NDD_SMR_genes_all_update_text_577417', 'Gene': 'DOC2A', 'topRSID': 'rs11646127', 'p_GWAS': 1.830278e-09, 'b_GWAS': -0.0493}, {'UUID': 'NDD_SMR_genes_all_update_text_577416', 'Gene': 'DOC2A', 'topRSID': 'rs11649149', 'p_GWAS': 8.144889e-09, 'b_GWAS': 0.0467}, {'UUID': 'NDD_SMR_genes_all_update_text_577424', 'Gene': 'DOC2A', 'topRSID': 'rs11863174', 'p_GWAS': 1.172318e-08, 'b_GWAS': 0.0462}, {'UUID': 'NDD_SMR_genes_all_update_text_109452', 'Gene': 'DOC2A', 'topRSID': 'rs12928610', 'p_GWAS': 1.564636e-08, 'b_GWAS': 0.0458}, {'UUID': 'NDD_SMR_genes_all_update_text_577426', 'Gene': 'DOC2A', 'topRSID': 'rs4788199', 'p_GWAS': 1.80597e-08, 'b_GWAS': 0.0456}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.976 | Q10 | Are there any USP43 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within USP43 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'USP43' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.790 | Q10 | Are there any RP11-261C10.3 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within RP11-261C10.3 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'RP11-261C10.3' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.742 | Q10 | Are there any LINC00519 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within LINC00519 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'LINC00519' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1044 | Q10 | Are there any TMPRSS5 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within TMPRSS5 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'TMPRSS5' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.979 | Q10 | Are there any FOXN4 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within FOXN4 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'FOXN4' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1526 | Q10 | Are there any SERPINA6 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within SERPINA6 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'SERPINA6' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1488 | Q10 | Are there any RP11-517P14.7 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within RP11-517P14.7 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'RP11-517P14.7' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1525 | Q10 | Are there any CTD-2135D7.2 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within CTD-2135D7.2 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'CTD-2135D7.2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1492 | Q10 | Are there any OR5K2 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within OR5K2 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'OR5K2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1694 | Q10 | Are there any RP11-65J3.2 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within RP11-65J3.2 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'RP11-65J3.2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1716 | Q10 | Are there any RP11-266O15.4 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within RP11-266O15.4 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'RP11-266O15.4' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1246 | Q10 | Are there any APH1B SNPs that have a statistically significant association with Alzheimer's Disease? | Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are at least 3 APH1B SNPs that are significantly associatied with Alzheimer's Disease:
• rs75763893 (GWAS p-value: 9.03e-20; b-value: -0.1092)
• rs76855300 (GWAS p-value: 6.53e-18; b-value: 0.1052)
• rs117618017 (GWAS p-value: 2.19e-21; b-value: 0.113) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'APH1B' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1395771', 'Gene': 'APH1B', 'topRSID': 'rs117618017', 'p_GWAS': 2.185304e-21, 'b_GWAS': 0.113}, {'UUID': 'NDD_SMR_genes_all_update_text_1110004', 'Gene': 'APH1B', 'topRSID': 'rs75763893', 'p_GWAS': 9.033182999999999e-20, 'b_GWAS': -0.1092}, {'UUID': 'NDD_SMR_genes_all_update_text_1500804', 'Gene': 'APH1B', 'topRSID': 'rs75763893', 'p_GWAS': 9.033182999999999e-20, 'b_GWAS': 0.1092}, {'UUID': 'NDD_SMR_genes_all_update_text_1290791', 'Gene': 'APH1B', 'topRSID': 'rs75763893', 'p_GWAS': 9.033183e-20, 'b_GWAS': 0.1092}, {'UUID': 'NDD_SMR_genes_all_update_text_1342451', 'Gene': 'APH1B', 'topRSID': 'rs76855300', 'p_GWAS': 6.525048e-18, 'b_GWAS': 0.1052}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.892 | Q10 | Are there any SNRNP70 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within SNRNP70 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'SNRNP70' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.82 | Q10 | Are there any DLL1 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within DLL1 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'DLL1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1182 | Q10 | Are there any SHC1 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within SHC1 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'SHC1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.821 | Q10 | Are there any PXN-AS1 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within PXN-AS1 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'PXN-AS1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1283 | Q10 | Are there any BIN1 SNPs that have a statistically significant association with Alzheimer's Disease? | Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there is at least 12 BIN1 SNP that are significantly associatied with Alzheimer's Disease:
• rs10194375 (GWAS p-value: 3.67e-29; b-value: 0.0964)
• rs11682128 (GWAS p-value: 4.12e-26; b-value: 0.0909)
• rs11694743 (GWAS p-value: 2.80e-23; b-value: 0.0825)
• rs1060743 (GWAS p-value: 2.10e-21; b-value: -0.0836)
• rs7559175 (GWAS p-value: 6.34e-20; b-value: 0.0859)
• rs58402148 (GWAS p-value: 2.26e-19; b-value: 0.0936)
• rs72846701 (GWAS p-value: 3.20e-19; b-value: -0.0932)
• rs62158731 (GWAS p-value: 2.50e-18; b-value: -0.0847)
• rs4663100 (GWAS p-value: 2.93e-18; b-value: 0.0854)
• rs934826 (GWAS p-value: 1.52e-13; b-value: 0.0709) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'BIN1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_631121', 'Gene': 'BIN1', 'topRSID': 'rs10194375', 'p_GWAS': 3.6707530000000003e-29, 'b_GWAS': 0.0964}, {'UUID': 'NDD_SMR_genes_all_update_text_631124', 'Gene': 'BIN1', 'topRSID': 'rs11682128', 'p_GWAS': 4.115138e-26, 'b_GWAS': 0.0909}, {'UUID': 'NDD_SMR_genes_all_update_text_1491965', 'Gene': 'BIN1', 'topRSID': 'rs11682128', 'p_GWAS': 4.115138e-26, 'b_GWAS': 0.0909}, {'UUID': 'NDD_SMR_genes_all_update_text_1647997', 'Gene': 'BIN1', 'topRSID': 'rs11694743', 'p_GWAS': 2.795024e-23, 'b_GWAS': 0.0825}, {'UUID': 'NDD_SMR_genes_all_update_text_46334', 'Gene': 'BIN1', 'topRSID': 'rs1060743', 'p_GWAS': 2.0989029999999998e-21, 'b_GWAS': -0.0836}, {'UUID': 'NDD_SMR_genes_all_update_text_486', 'Gene': 'BIN1', 'topRSID': 'rs7559175', 'p_GWAS': 6.344298e-20, 'b_GWAS': 0.0859}, {'UUID': 'NDD_SMR_genes_all_update_text_631119', 'Gene': 'BIN1', 'topRSID': 'rs58402148', 'p_GWAS': 2.2571769999999997e-19, 'b_GWAS': 0.0936}, {'UUID': 'NDD_SMR_genes_all_update_text_46338', 'Gene': 'BIN1', 'topRSID': 'rs72846701', 'p_GWAS': 3.201795e-19, 'b_GWAS': -0.0932}, {'UUID': 'NDD_SMR_genes_all_update_text_1390118', 'Gene': 'BIN1', 'topRSID': 'rs62158731', 'p_GWAS': 2.5029950000000002e-18, 'b_GWAS': -0.0847}, {'UUID': 'NDD_SMR_genes_all_update_text_1686596', 'Gene': 'BIN1', 'topRSID': 'rs62158731', 'p_GWAS': 2.5029950000000002e-18, 'b_GWAS': -0.0847}, {'UUID': 'NDD_SMR_genes_all_update_text_1171776', 'Gene': 'BIN1', 'topRSID': 'rs4663100', 'p_GWAS': 2.9259760000000002e-18, 'b_GWAS': 0.0854}, {'UUID': 'NDD_SMR_genes_all_update_text_631116', 'Gene': 'BIN1', 'topRSID': 'rs934826', 'p_GWAS': 1.519767e-13, 'b_GWAS': -0.0709}, {'UUID': 'NDD_SMR_genes_all_update_text_46336', 'Gene': 'BIN1', 'topRSID': 'rs934826', 'p_GWAS': 1.519767e-13, 'b_GWAS': 0.0709}, {'UUID': 'NDD_SMR_genes_all_update_text_631123', 'Gene': 'BIN1', 'topRSID': 'rs34212842', 'p_GWAS': 1.590867e-10, 'b_GWAS': 0.071}, {'UUID': 'NDD_SMR_genes_all_update_text_631125', 'Gene': 'BIN1', 'topRSID': 'rs6720234', 'p_GWAS': 3.927535e-10, 'b_GWAS': 0.0682}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.678 | Q10 | Are there any RN7SL199P SNPs that have a statistically significant association with Alzheimer's Disease? | Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there is at least 1 RN7SL199P SNP that are significantly associatied with Alzheimer's Disease:
• rs199447 (GWAS p-value: 6.63e-09; b-value: -0.058) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'RN7SL199P' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1203021', 'Gene': 'RN7SL199P', 'topRSID': 'rs199447', 'p_GWAS': 6.631492e-09, 'b_GWAS': -0.058}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1533 | Q10 | Are there any ZSCAN31 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within ZSCAN31 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'ZSCAN31' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.59 | Q10 | Are there any LCE3A SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within LCE3A that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'LCE3A' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.136 | Q10 | Are there any RP1-290I10.3 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within RP1-290I10.3 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'RP1-290I10.3' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1150 | Q10 | Are there any NDUFAF2 SNPs that have a statistically significant association with Parkinson's Disease? | Yes, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are at least 3 NDUFAF2 SNPs that are significantly associatied with Parkinson's Disease:
• rs10064187 (GWAS p-value: 3.43e-08; b-value: -0.1076)
• rs158938 (GWAS p-value: 1.96e-08; b-value: -0.1095)
• rs2619893 (GWAS p-value: 1.74e-08; b-value: 0.1116) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'NDUFAF2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1556333', 'Gene': 'NDUFAF2', 'topRSID': 'rs2619893', 'p_GWAS': 1.736784e-08, 'b_GWAS': 0.1116}, {'UUID': 'NDD_SMR_genes_all_update_text_1236774', 'Gene': 'NDUFAF2', 'topRSID': 'rs158938', 'p_GWAS': 1.961255e-08, 'b_GWAS': -0.1095}, {'UUID': 'NDD_SMR_genes_all_update_text_1430673', 'Gene': 'NDUFAF2', 'topRSID': 'rs158938', 'p_GWAS': 1.961255e-08, 'b_GWAS': 0.1095}, {'UUID': 'NDD_SMR_genes_all_update_text_1141694', 'Gene': 'NDUFAF2', 'topRSID': 'rs10064187', 'p_GWAS': 3.429795e-08, 'b_GWAS': -0.1076}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.942 | Q10 | Are there any BCAM SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within BCAM that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'BCAM' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1685 | Q10 | Are there any CCDC183-AS1 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within CCDC183-AS1 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'CCDC183-AS1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.830 | Q10 | Are there any RP5-997D16.2 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within RP5-997D16.2 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'RP5-997D16.2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1224 | Q10 | Are there any CYP2D7P1 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within CYP2D7P1 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'CYP2D7P1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.510 | Q10 | Are there any AC019048.1 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within AC019048.1 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'AC019048.1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1776 | Q10 | Are there any RP11-799B12.2 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within RP11-799B12.2 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'RP11-799B12.2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.351 | Q10 | Are there any EPHX2 SNPs that have a statistically significant association with Alzheimer's Disease? | Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are at least 2 EPHX2 SNPs that are significantly associatied with Alzheimer's Disease:
• rs10104713 (GWAS p-value: 4.05e-08; b-value: -0.0719)
• rs17057245 (GWAS p-value: 4.05e-08; b-value: -0.0719) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'EPHX2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_78250', 'Gene': 'EPHX2', 'topRSID': 'rs10104713', 'p_GWAS': 4.052474e-08, 'b_GWAS': -0.0719}, {'UUID': 'NDD_SMR_genes_all_update_text_78253', 'Gene': 'EPHX2', 'topRSID': 'rs17057245', 'p_GWAS': 4.052474e-08, 'b_GWAS': -0.0719}, {'UUID': 'NDD_SMR_genes_all_update_text_1288155', 'Gene': 'EPHX2', 'topRSID': 'rs17057245', 'p_GWAS': 4.052474e-08, 'b_GWAS': 0.0719}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.392 | Q10 | Are there any RP11-698N11.2 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within RP11-698N11.2 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'RP11-698N11.2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1033 | Q10 | Are there any ABCD2 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within ABCD2 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'ABCD2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.901 | Q10 | Are there any RN7SL199P SNPs that have a statistically significant association with Parkinson's Disease? | Yes, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there is at least 1 RN7SL199P SNP that are significantly associatied with Parkinson's Disease:
• rs2950694 (GWAS p-value: 3.53e-11; b-value: -0.2212) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'RN7SL199P' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1242286', 'Gene': 'RN7SL199P', 'topRSID': 'rs2950694', 'p_GWAS': 3.525663e-11, 'b_GWAS': -0.2212}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.835 | Q10 | Are there any MEF2BNB SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within MEF2BNB that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'MEF2BNB' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1894 | Q10 | Are there any B4GALT3 SNPs that have a statistically significant association with Alzheimer's Disease? | Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are at least 2 B4GALT3 SNPs that are significantly associatied with Alzheimer's Disease:
• rs4233366 (GWAS p-value: 1.46e-08; b-value: -0.0527)
• rs11585858 (GWAS p-value: 1.90e-08; b-value: 0.0534) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'B4GALT3' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1284734', 'Gene': 'B4GALT3', 'topRSID': 'rs4233366', 'p_GWAS': 1.456022e-08, 'b_GWAS': -0.0527}, {'UUID': 'NDD_SMR_genes_all_update_text_1490905', 'Gene': 'B4GALT3', 'topRSID': 'rs11585858', 'p_GWAS': 1.897974e-08, 'b_GWAS': 0.0534}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.481 | Q10 | Are there any C12orf41 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within C12orf41 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'C12orf41' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1472 | Q10 | Are there any TEAD2 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within TEAD2 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'TEAD2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1887 | Q10 | Are there any RP11-1252D15.1 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within RP11-1252D15.1 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'RP11-1252D15.1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1398 | Q10 | Are there any ZC3HC1 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within ZC3HC1 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'ZC3HC1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.659 | Q10 | Are there any C19orf53 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within C19orf53 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'C19orf53' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.175 | Q10 | Are there any TIMM50 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within TIMM50 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'TIMM50' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1159 | Q10 | Are there any ZNF517 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within ZNF517 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'ZNF517' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.39 | Q10 | Are there any SULT2B1 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within SULT2B1 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'SULT2B1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.720 | Q10 | Are there any RP11-986E7.7 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within RP11-986E7.7 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'RP11-986E7.7' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.93 | Q10 | Are there any LOC348840 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within LOC348840 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'LOC348840' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1937 | Q10 | Are there any HNRNPA2B1 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within HNRNPA2B1 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'HNRNPA2B1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1215 | Q10 | Are there any LGALS14 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within LGALS14 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'LGALS14' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
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