uuid stringlengths 4 8 | template_uuid stringclasses 40 values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 138 627 | execution_results stringlengths 2 1.14M | query_type stringclasses 2 values | sql_category stringclasses 26 values | bio_category stringclasses 14 values |
|---|---|---|---|---|---|---|---|---|
Q10.1709 | Q10 | Are there any ITGA2B SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within ITGA2B that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'ITGA2B' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1000 | Q10 | Are there any RP4-635E18.7 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within RP4-635E18.7 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'RP4-635E18.7' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.883 | Q10 | Are there any AFMID SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within AFMID that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'AFMID' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.780 | Q10 | Are there any GPR15 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within GPR15 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'GPR15' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1229 | Q10 | Are there any TUBB8P7 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within TUBB8P7 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'TUBB8P7' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.2000 | Q10 | Are there any CEBPG SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within CEBPG that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'CEBPG' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.5 | Q10 | Are there any SLC30A6 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within SLC30A6 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'SLC30A6' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1012 | Q10 | Are there any C7orf30 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within C7orf30 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'C7orf30' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1724 | Q10 | Are there any GOLGA8J SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within GOLGA8J that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'GOLGA8J' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.266 | Q10 | Are there any CEP104 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within CEP104 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'CEP104' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1570 | Q10 | Are there any RBM12B SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within RBM12B that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'RBM12B' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1832 | Q10 | Are there any AC016735.1 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within AC016735.1 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'AC016735.1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.449 | Q10 | Are there any ZNF766 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within ZNF766 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'ZNF766' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1011 | Q10 | Are there any PPFIA3 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within PPFIA3 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'PPFIA3' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1086 | Q10 | Are there any ZKSCAN1 SNPs that have a statistically significant association with Alzheimer's Disease? | Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there is at least 1 ZKSCAN1 SNP that are significantly associatied with Alzheimer's Disease:
• rs6465761 (GWAS p-value: 7.06e-10; b-value: -0.0561) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'ZKSCAN1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1340308', 'Gene': 'ZKSCAN1', 'topRSID': 'rs6465761', 'p_GWAS': 7.05566e-10, 'b_GWAS': -0.0561}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.844 | Q10 | Are there any SOAT1 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within SOAT1 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'SOAT1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1792 | Q10 | Are there any C12orf40 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within C12orf40 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'C12orf40' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.308 | Q10 | Are there any RP3-395M20.9 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within RP3-395M20.9 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'RP3-395M20.9' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1380 | Q10 | Are there any FAM78B SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within FAM78B that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'FAM78B' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1558 | Q10 | Are there any CCDC129 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within CCDC129 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'CCDC129' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.317 | Q10 | Are there any RASA1 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within RASA1 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'RASA1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.152 | Q10 | Are there any ZNF646 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within ZNF646 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'ZNF646' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1158 | Q10 | Are there any ADAP2 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within ADAP2 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'ADAP2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1223 | Q10 | Are there any RP11-89K18.1 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within RP11-89K18.1 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'RP11-89K18.1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.580 | Q10 | Are there any LINC00984 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within LINC00984 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'LINC00984' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.51 | Q10 | Are there any AP001877.1 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within AP001877.1 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'AP001877.1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1553 | Q10 | Are there any RP11-844P9.2 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within RP11-844P9.2 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'RP11-844P9.2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.733 | Q10 | Are there any TP53INP2 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within TP53INP2 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'TP53INP2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.840 | Q10 | Are there any NOX4 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within NOX4 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'NOX4' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1392 | Q10 | Are there any AICDA SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within AICDA that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'AICDA' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1125 | Q10 | Are there any TSGA10 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within TSGA10 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'TSGA10' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1176 | Q10 | Are there any ZNF296 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within ZNF296 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'ZNF296' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.476 | Q10 | Are there any PTCD1 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within PTCD1 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'PTCD1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.980 | Q10 | Are there any CRHR1 SNPs that have a statistically significant association with Alzheimer's Disease? | Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are at least 6 CRHR1 SNPs that are significantly associatied with Alzheimer's Disease:
• rs878888 (GWAS p-value: 4.78e-08; b-value: -0.0535)
• rs17689882 (GWAS p-value: 4.39e-08; b-value: -0.0531)
• rs2668632 (GWAS p-value: 4.64e-08; b-value: 0.0541)
• rs79923708 (GWAS p-value: 3.29e-08; b-value: -0.0547)
• rs8070723 (GWAS p-value: 2.25e-08; b-value: -0.0548)
• rs199439 (GWAS p-value: 3.64e-09; b-value: -0.059) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'CRHR1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1343152', 'Gene': 'CRHR1', 'topRSID': 'rs199439', 'p_GWAS': 3.635016e-09, 'b_GWAS': -0.059}, {'UUID': 'NDD_SMR_genes_all_update_text_1291758', 'Gene': 'CRHR1', 'topRSID': 'rs8070723', 'p_GWAS': 2.2468e-08, 'b_GWAS': -0.0548}, {'UUID': 'NDD_SMR_genes_all_update_text_1203006', 'Gene': 'CRHR1', 'topRSID': 'rs79923708', 'p_GWAS': 3.29012e-08, 'b_GWAS': -0.0547}, {'UUID': 'NDD_SMR_genes_all_update_text_591172', 'Gene': 'CRHR1', 'topRSID': 'rs17689882', 'p_GWAS': 4.39426e-08, 'b_GWAS': -0.0531}, {'UUID': 'NDD_SMR_genes_all_update_text_1106827', 'Gene': 'CRHR1', 'topRSID': 'rs2668632', 'p_GWAS': 4.638303e-08, 'b_GWAS': 0.0541}, {'UUID': 'NDD_SMR_genes_all_update_text_115155', 'Gene': 'CRHR1', 'topRSID': 'rs878888', 'p_GWAS': 4.783287e-08, 'b_GWAS': -0.0535}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.660 | Q10 | Are there any RP11-477N3.1 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within RP11-477N3.1 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'RP11-477N3.1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.405 | Q10 | Are there any RELL2 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within RELL2 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'RELL2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.517 | Q10 | Are there any ZNF114 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within ZNF114 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'ZNF114' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.324 | Q10 | Are there any GSS SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within GSS that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'GSS' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.20 | Q10 | Are there any KB-431C1.3 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within KB-431C1.3 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'KB-431C1.3' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.691 | Q10 | Are there any MS4A18 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within MS4A18 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'MS4A18' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.36 | Q10 | Are there any CTB-14A14.2 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within CTB-14A14.2 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'CTB-14A14.2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.910 | Q10 | Are there any FAM215B SNPs that have a statistically significant association with Progressive supranuclear palsy? | Yes, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are at least 4 FAM215B SNPs that are significantly associatied with Progressive supranuclear palsy:
• rs415430 (GWAS p-value: 9.28e-44; b-value: -1.482)
• rs17692129 (GWAS p-value: 5.79e-22; b-value: -0.5568)
• rs11012 (GWAS p-value: 2.11e-42; b-value: 1.608)
• rs169201 (GWAS p-value: 8.55e-46; b-value: 1.588) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'FAM215B' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1714165', 'Gene': 'FAM215B', 'topRSID': 'rs169201', 'p_GWAS': 8.550985e-46, 'b_GWAS': 1.5881}, {'UUID': 'NDD_SMR_genes_all_update_text_1194225', 'Gene': 'FAM215B', 'topRSID': 'rs415430', 'p_GWAS': 9.277259e-44, 'b_GWAS': -1.4816}, {'UUID': 'NDD_SMR_genes_all_update_text_1646052', 'Gene': 'FAM215B', 'topRSID': 'rs11012', 'p_GWAS': 2.10769e-42, 'b_GWAS': 1.6076}, {'UUID': 'NDD_SMR_genes_all_update_text_1336300', 'Gene': 'FAM215B', 'topRSID': 'rs17692129', 'p_GWAS': 5.788764e-22, 'b_GWAS': -0.5568}, {'UUID': 'NDD_SMR_genes_all_update_text_1579431', 'Gene': 'FAM215B', 'topRSID': 'rs17692129', 'p_GWAS': 5.788764e-22, 'b_GWAS': -0.5568}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.834 | Q10 | Are there any TIMELESS SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within TIMELESS that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'TIMELESS' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1798 | Q10 | Are there any MAPK13 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within MAPK13 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'MAPK13' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.413 | Q10 | Are there any MAPT-AS1 SNPs that have a statistically significant association with Progressive supranuclear palsy? | Yes, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are at least 6 MAPT-AS1 SNPs that are significantly associatied with Progressive supranuclear palsy:
• rs12373139 (GWAS p-value: 4.65e-51; b-value: 1.688)
• rs1981997 (GWAS p-value: 1.79e-51; b-value: 1.715)
• rs169201 (GWAS p-value: 8.55e-46; b-value: 1.588)
• rs415430 (GWAS p-value: 9.28e-44; b-value: 1.482)
• rs393152 (GWAS p-value: 8.30e-51; b-value: 1.652)
• rs11012 (GWAS p-value: 2.11e-42; b-value: 1.608) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'MAPT-AS1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_560854', 'Gene': 'MAPT-AS1', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1464417', 'Gene': 'MAPT-AS1', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_560852', 'Gene': 'MAPT-AS1', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_560853', 'Gene': 'MAPT-AS1', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_560851', 'Gene': 'MAPT-AS1', 'topRSID': 'rs12373139', 'p_GWAS': 4.6506369999999996e-51, 'b_GWAS': 1.6879}, {'UUID': 'NDD_SMR_genes_all_update_text_560850', 'Gene': 'MAPT-AS1', 'topRSID': 'rs12373139', 'p_GWAS': 4.6506369999999996e-51, 'b_GWAS': 1.6879}, {'UUID': 'NDD_SMR_genes_all_update_text_1732394', 'Gene': 'MAPT-AS1', 'topRSID': 'rs393152', 'p_GWAS': 8.302968999999999e-51, 'b_GWAS': 1.6521}, {'UUID': 'NDD_SMR_genes_all_update_text_1283701', 'Gene': 'MAPT-AS1', 'topRSID': 'rs393152', 'p_GWAS': 8.302968999999999e-51, 'b_GWAS': 1.6521}, {'UUID': 'NDD_SMR_genes_all_update_text_1041726', 'Gene': 'MAPT-AS1', 'topRSID': 'rs169201', 'p_GWAS': 8.550985e-46, 'b_GWAS': 1.5881}, {'UUID': 'NDD_SMR_genes_all_update_text_1041728', 'Gene': 'MAPT-AS1', 'topRSID': 'rs169201', 'p_GWAS': 8.550985e-46, 'b_GWAS': 1.5881}, {'UUID': 'NDD_SMR_genes_all_update_text_1041729', 'Gene': 'MAPT-AS1', 'topRSID': 'rs169201', 'p_GWAS': 8.550985e-46, 'b_GWAS': 1.5881}, {'UUID': 'NDD_SMR_genes_all_update_text_1041730', 'Gene': 'MAPT-AS1', 'topRSID': 'rs169201', 'p_GWAS': 8.550985e-46, 'b_GWAS': 1.5881}, {'UUID': 'NDD_SMR_genes_all_update_text_1041727', 'Gene': 'MAPT-AS1', 'topRSID': 'rs415430', 'p_GWAS': 9.277259e-44, 'b_GWAS': 1.4816}, {'UUID': 'NDD_SMR_genes_all_update_text_1375928', 'Gene': 'MAPT-AS1', 'topRSID': 'rs11012', 'p_GWAS': 2.10769e-42, 'b_GWAS': 1.6076}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.928 | Q10 | Are there any RP11-707O23.5 SNPs that have a statistically significant association with Alzheimer's Disease? | Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are at least 5 RP11-707O23.5 SNPs that are significantly associatied with Alzheimer's Disease:
• rs55974014 (GWAS p-value: 1.54e-08; b-value: -0.056)
• rs2732705 (GWAS p-value: 2.86e-08; b-value: -0.0555)
• rs62056812 (GWAS p-value: 3.38e-08; b-value: -0.0541)
• rs9468 (GWAS p-value: 2.00e-08; b-value: -0.055)
• rs2532233 (GWAS p-value: 3.69e-08; b-value: -0.0545) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'RP11-707O23.5' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1480156', 'Gene': 'RP11-707O23.5', 'topRSID': 'rs55974014', 'p_GWAS': 1.544319e-08, 'b_GWAS': -0.056}, {'UUID': 'NDD_SMR_genes_all_update_text_1343150', 'Gene': 'RP11-707O23.5', 'topRSID': 'rs55974014', 'p_GWAS': 1.544319e-08, 'b_GWAS': -0.056}, {'UUID': 'NDD_SMR_genes_all_update_text_1291755', 'Gene': 'RP11-707O23.5', 'topRSID': 'rs55974014', 'p_GWAS': 1.544319e-08, 'b_GWAS': -0.056}, {'UUID': 'NDD_SMR_genes_all_update_text_1690042', 'Gene': 'RP11-707O23.5', 'topRSID': 'rs55974014', 'p_GWAS': 1.544319e-08, 'b_GWAS': -0.056}, {'UUID': 'NDD_SMR_genes_all_update_text_1268112', 'Gene': 'RP11-707O23.5', 'topRSID': 'rs55974014', 'p_GWAS': 1.544319e-08, 'b_GWAS': -0.056}, {'UUID': 'NDD_SMR_genes_all_update_text_1454353', 'Gene': 'RP11-707O23.5', 'topRSID': 'rs55974014', 'p_GWAS': 1.544319e-08, 'b_GWAS': -0.056}, {'UUID': 'NDD_SMR_genes_all_update_text_1157198', 'Gene': 'RP11-707O23.5', 'topRSID': 'rs55974014', 'p_GWAS': 1.544319e-08, 'b_GWAS': -0.056}, {'UUID': 'NDD_SMR_genes_all_update_text_1446734', 'Gene': 'RP11-707O23.5', 'topRSID': 'rs55974014', 'p_GWAS': 1.544319e-08, 'b_GWAS': -0.056}, {'UUID': 'NDD_SMR_genes_all_update_text_1652496', 'Gene': 'RP11-707O23.5', 'topRSID': 'rs55974014', 'p_GWAS': 1.544319e-08, 'b_GWAS': -0.056}, {'UUID': 'NDD_SMR_genes_all_update_text_1378567', 'Gene': 'RP11-707O23.5', 'topRSID': 'rs9468', 'p_GWAS': 1.997185e-08, 'b_GWAS': -0.055}, {'UUID': 'NDD_SMR_genes_all_update_text_1203002', 'Gene': 'RP11-707O23.5', 'topRSID': 'rs2732705', 'p_GWAS': 2.856696e-08, 'b_GWAS': -0.0555}, {'UUID': 'NDD_SMR_genes_all_update_text_1247081', 'Gene': 'RP11-707O23.5', 'topRSID': 'rs62056812', 'p_GWAS': 3.382131e-08, 'b_GWAS': -0.0541}, {'UUID': 'NDD_SMR_genes_all_update_text_1502445', 'Gene': 'RP11-707O23.5', 'topRSID': 'rs2532233', 'p_GWAS': 3.690625e-08, 'b_GWAS': -0.0545}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.543 | Q10 | Are there any ABCF3 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within ABCF3 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'ABCF3' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.765 | Q10 | Are there any CCL3L1 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within CCL3L1 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'CCL3L1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1905 | Q10 | Are there any ZNF585A SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within ZNF585A that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'ZNF585A' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1071 | Q10 | Are there any FCGRT SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within FCGRT that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'FCGRT' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1209 | Q10 | Are there any IL33 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within IL33 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'IL33' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.248 | Q10 | Are there any RP11-356M20.1 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within RP11-356M20.1 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'RP11-356M20.1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1431 | Q10 | Are there any EFCAB4B SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within EFCAB4B that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'EFCAB4B' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1137 | Q10 | Are there any RP11-259G18.1 SNPs that have a statistically significant association with Alzheimer's Disease? | Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there is at least 10 RP11-259G18.1 SNP that are significantly associatied with Alzheimer's Disease:
• rs373695612 (GWAS p-value: 5.43e-09; b-value: -0.0595)
• rs62073157 (GWAS p-value: 3.69e-08; b-value: -0.0545)
• rs4564621 (GWAS p-value: 4.15e-08; b-value: -0.0532)
• rs73984689 (GWAS p-value: 3.11e-08; b-value: -0.0548)
• rs17652520 (GWAS p-value: 1.24e-08; b-value: -0.0558)
• rs62061714 (GWAS p-value: 3.58e-08; b-value: -0.054)
• rs2532233 (GWAS p-value: 3.69e-08; b-value: -0.0545)
• rs757055 (GWAS p-value: 3.58e-08; b-value: -0.054)
• rs753236 (GWAS p-value: 2.12e-08; b-value: -0.0549)
• rs62057147 (GWAS p-value: 3.48e-08; b-value: -0.0535) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'RP11-259G18.1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_115228', 'Gene': 'RP11-259G18.1', 'topRSID': 'rs373695612', 'p_GWAS': 5.433087e-09, 'b_GWAS': -0.0595}, {'UUID': 'NDD_SMR_genes_all_update_text_1247087', 'Gene': 'RP11-259G18.1', 'topRSID': 'rs17652520', 'p_GWAS': 1.241862e-08, 'b_GWAS': -0.0558}, {'UUID': 'NDD_SMR_genes_all_update_text_1598272', 'Gene': 'RP11-259G18.1', 'topRSID': 'rs753236', 'p_GWAS': 2.118427e-08, 'b_GWAS': -0.0549}, {'UUID': 'NDD_SMR_genes_all_update_text_1203015', 'Gene': 'RP11-259G18.1', 'topRSID': 'rs73984689', 'p_GWAS': 3.106012e-08, 'b_GWAS': -0.0548}, {'UUID': 'NDD_SMR_genes_all_update_text_1610869', 'Gene': 'RP11-259G18.1', 'topRSID': 'rs62057147', 'p_GWAS': 3.478611e-08, 'b_GWAS': -0.0535}, {'UUID': 'NDD_SMR_genes_all_update_text_1717381', 'Gene': 'RP11-259G18.1', 'topRSID': 'rs62057147', 'p_GWAS': 3.478611e-08, 'b_GWAS': -0.0535}, {'UUID': 'NDD_SMR_genes_all_update_text_1291764', 'Gene': 'RP11-259G18.1', 'topRSID': 'rs62061714', 'p_GWAS': 3.584179e-08, 'b_GWAS': -0.054}, {'UUID': 'NDD_SMR_genes_all_update_text_1584314', 'Gene': 'RP11-259G18.1', 'topRSID': 'rs757055', 'p_GWAS': 3.584179e-08, 'b_GWAS': -0.054}, {'UUID': 'NDD_SMR_genes_all_update_text_115229', 'Gene': 'RP11-259G18.1', 'topRSID': 'rs62073157', 'p_GWAS': 3.690625e-08, 'b_GWAS': -0.0545}, {'UUID': 'NDD_SMR_genes_all_update_text_1502452', 'Gene': 'RP11-259G18.1', 'topRSID': 'rs2532233', 'p_GWAS': 3.690625e-08, 'b_GWAS': -0.0545}, {'UUID': 'NDD_SMR_genes_all_update_text_1174601', 'Gene': 'RP11-259G18.1', 'topRSID': 'rs4564621', 'p_GWAS': 4.145559e-08, 'b_GWAS': -0.0532}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.791 | Q10 | Are there any AC007950.1 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within AC007950.1 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'AC007950.1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1744 | Q10 | Are there any MRPS18B SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within MRPS18B that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'MRPS18B' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.495 | Q10 | Are there any CALML5 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within CALML5 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'CALML5' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.157 | Q10 | Are there any DLX5 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within DLX5 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'DLX5' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.970 | Q10 | Are there any ZSWIM7 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within ZSWIM7 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'ZSWIM7' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.860 | Q10 | Are there any KANSL1-AS1 SNPs that have a statistically significant association with Alzheimer's Disease? | Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are at least 9 KANSL1-AS1 SNPs that are significantly associatied with Alzheimer's Disease:
• rs199533 (GWAS p-value: 1.29e-08; b-value: -0.0563)
• rs55974014 (GWAS p-value: 1.54e-08; b-value: -0.056)
• rs199447 (GWAS p-value: 6.63e-09; b-value: -0.058)
• rs199456 (GWAS p-value: 3.03e-09; b-value: -0.0593)
• rs12185243 (GWAS p-value: 2.25e-08; b-value: -0.0548)
• rs9468 (GWAS p-value: 2.00e-08; b-value: -0.055)
• rs2532233 (GWAS p-value: 3.69e-08; b-value: -0.0545)
• rs9896243 (GWAS p-value: 1.51e-08; b-value: -0.0566)
• rs1378358 (GWAS p-value: 4.92e-09; b-value: 0.0585) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'KANSL1-AS1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1291761', 'Gene': 'KANSL1-AS1', 'topRSID': 'rs199456', 'p_GWAS': 3.029347e-09, 'b_GWAS': -0.0593}, {'UUID': 'NDD_SMR_genes_all_update_text_1652499', 'Gene': 'KANSL1-AS1', 'topRSID': 'rs199456', 'p_GWAS': 3.029347e-09, 'b_GWAS': -0.0593}, {'UUID': 'NDD_SMR_genes_all_update_text_1610866', 'Gene': 'KANSL1-AS1', 'topRSID': 'rs1378358', 'p_GWAS': 4.91573e-09, 'b_GWAS': 0.0585}, {'UUID': 'NDD_SMR_genes_all_update_text_1203012', 'Gene': 'KANSL1-AS1', 'topRSID': 'rs199447', 'p_GWAS': 6.631492e-09, 'b_GWAS': -0.058}, {'UUID': 'NDD_SMR_genes_all_update_text_1454357', 'Gene': 'KANSL1-AS1', 'topRSID': 'rs199533', 'p_GWAS': 1.293899e-08, 'b_GWAS': -0.0563}, {'UUID': 'NDD_SMR_genes_all_update_text_1480159', 'Gene': 'KANSL1-AS1', 'topRSID': 'rs199533', 'p_GWAS': 1.293899e-08, 'b_GWAS': -0.0563}, {'UUID': 'NDD_SMR_genes_all_update_text_1157200', 'Gene': 'KANSL1-AS1', 'topRSID': 'rs199533', 'p_GWAS': 1.293899e-08, 'b_GWAS': -0.0563}, {'UUID': 'NDD_SMR_genes_all_update_text_1268116', 'Gene': 'KANSL1-AS1', 'topRSID': 'rs199533', 'p_GWAS': 1.293899e-08, 'b_GWAS': -0.0563}, {'UUID': 'NDD_SMR_genes_all_update_text_1378569', 'Gene': 'KANSL1-AS1', 'topRSID': 'rs199533', 'p_GWAS': 1.293899e-08, 'b_GWAS': -0.0563}, {'UUID': 'NDD_SMR_genes_all_update_text_1598269', 'Gene': 'KANSL1-AS1', 'topRSID': 'rs9896243', 'p_GWAS': 1.51373e-08, 'b_GWAS': -0.0566}, {'UUID': 'NDD_SMR_genes_all_update_text_1247084', 'Gene': 'KANSL1-AS1', 'topRSID': 'rs55974014', 'p_GWAS': 1.544319e-08, 'b_GWAS': -0.056}, {'UUID': 'NDD_SMR_genes_all_update_text_1690046', 'Gene': 'KANSL1-AS1', 'topRSID': 'rs55974014', 'p_GWAS': 1.544319e-08, 'b_GWAS': -0.056}, {'UUID': 'NDD_SMR_genes_all_update_text_1717378', 'Gene': 'KANSL1-AS1', 'topRSID': 'rs55974014', 'p_GWAS': 1.544319e-08, 'b_GWAS': -0.056}, {'UUID': 'NDD_SMR_genes_all_update_text_1343155', 'Gene': 'KANSL1-AS1', 'topRSID': 'rs55974014', 'p_GWAS': 1.544319e-08, 'b_GWAS': -0.056}, {'UUID': 'NDD_SMR_genes_all_update_text_1174598', 'Gene': 'KANSL1-AS1', 'topRSID': 'rs55974014', 'p_GWAS': 1.544319e-08, 'b_GWAS': -0.056}, {'UUID': 'NDD_SMR_genes_all_update_text_1396750', 'Gene': 'KANSL1-AS1', 'topRSID': 'rs55974014', 'p_GWAS': 1.544319e-08, 'b_GWAS': -0.056}, {'UUID': 'NDD_SMR_genes_all_update_text_1584311', 'Gene': 'KANSL1-AS1', 'topRSID': 'rs55974014', 'p_GWAS': 1.544319e-08, 'b_GWAS': -0.056}, {'UUID': 'NDD_SMR_genes_all_update_text_1466646', 'Gene': 'KANSL1-AS1', 'topRSID': 'rs9468', 'p_GWAS': 1.997185e-08, 'b_GWAS': -0.055}, {'UUID': 'NDD_SMR_genes_all_update_text_1446736', 'Gene': 'KANSL1-AS1', 'topRSID': 'rs12185243', 'p_GWAS': 2.2468e-08, 'b_GWAS': -0.0548}, {'UUID': 'NDD_SMR_genes_all_update_text_1502449', 'Gene': 'KANSL1-AS1', 'topRSID': 'rs2532233', 'p_GWAS': 3.690625e-08, 'b_GWAS': -0.0545}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1325 | Q10 | Are there any JPH4 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within JPH4 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'JPH4' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.632 | Q10 | Are there any AC022498.1 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within AC022498.1 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'AC022498.1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.692 | Q10 | Are there any RP11-1079K10.3 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within RP11-1079K10.3 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'RP11-1079K10.3' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1562 | Q10 | Are there any DEFB134 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within DEFB134 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'DEFB134' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.575 | Q10 | Are there any RAB20 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within RAB20 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'RAB20' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1909 | Q10 | Are there any TSPEAR-AS1 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within TSPEAR-AS1 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'TSPEAR-AS1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.18 | Q10 | Are there any NUDT1 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within NUDT1 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'NUDT1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.130 | Q10 | Are there any TAS2R60 SNPs that have a statistically significant association with Alzheimer's Disease? | Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are at least 2 TAS2R60 SNPs that are significantly associatied with Alzheimer's Disease:
• rs11771145 (GWAS p-value: 1.20e-12; b-value: -0.0604)
• rs11769559 (GWAS p-value: 2.92e-16; b-value: -0.0695) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'TAS2R60' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1649765', 'Gene': 'TAS2R60', 'topRSID': 'rs11769559', 'p_GWAS': 2.922788e-16, 'b_GWAS': -0.0695}, {'UUID': 'NDD_SMR_genes_all_update_text_1496072', 'Gene': 'TAS2R60', 'topRSID': 'rs11771145', 'p_GWAS': 1.195562e-12, 'b_GWAS': -0.0604}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1361 | Q10 | Are there any RP11-85M11.2 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within RP11-85M11.2 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'RP11-85M11.2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1291 | Q10 | Are there any MIA2 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within MIA2 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'MIA2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1969 | Q10 | Are there any CTC-325J23.3 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within CTC-325J23.3 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'CTC-325J23.3' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.935 | Q10 | Are there any RP11-91J19.4 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within RP11-91J19.4 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'RP11-91J19.4' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.989 | Q10 | Are there any RP11-421L21.3 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within RP11-421L21.3 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'RP11-421L21.3' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1965 | Q10 | Are there any KANSL1 SNPs that have a statistically significant association with Alzheimer's Disease? | Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there is at least 16 KANSL1 SNP that are significantly associatied with Alzheimer's Disease:
• rs199451 (GWAS p-value: 2.85e-09; b-value: 0.0594)
• rs199457 (GWAS p-value: 3.22e-09; b-value: 0.0592)
• rs199447 (GWAS p-value: 6.63e-09; b-value: -0.058)
• rs62062271 (GWAS p-value: 1.10e-08; b-value: -0.056)
• rs70600 (GWAS p-value: 1.27e-08; b-value: -0.0569)
• rs199533 (GWAS p-value: 1.29e-08; b-value: 0.0563)
• rs199525 (GWAS p-value: 1.35e-08; b-value: -0.0568)
• rs12150087 (GWAS p-value: 2.07e-08; b-value: -0.0555)
• rs41374248 (GWAS p-value: 2.25e-08; b-value: -0.0548)
• rs2668665 (GWAS p-value: 3.11e-08; b-value: -0.0548) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'KANSL1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_28413', 'Gene': 'KANSL1', 'topRSID': 'rs199451', 'p_GWAS': 2.850221e-09, 'b_GWAS': 0.0594}, {'UUID': 'NDD_SMR_genes_all_update_text_1106830', 'Gene': 'KANSL1', 'topRSID': 'rs199457', 'p_GWAS': 3.219416e-09, 'b_GWAS': 0.0592}, {'UUID': 'NDD_SMR_genes_all_update_text_1203011', 'Gene': 'KANSL1', 'topRSID': 'rs199447', 'p_GWAS': 6.631492e-09, 'b_GWAS': -0.058}, {'UUID': 'NDD_SMR_genes_all_update_text_1396749', 'Gene': 'KANSL1', 'topRSID': 'rs199447', 'p_GWAS': 6.631492e-09, 'b_GWAS': -0.058}, {'UUID': 'NDD_SMR_genes_all_update_text_115199', 'Gene': 'KANSL1', 'topRSID': 'rs62062271', 'p_GWAS': 1.101658e-08, 'b_GWAS': -0.056}, {'UUID': 'NDD_SMR_genes_all_update_text_24565', 'Gene': 'KANSL1', 'topRSID': 'rs70600', 'p_GWAS': 1.270394e-08, 'b_GWAS': -0.0569}, {'UUID': 'NDD_SMR_genes_all_update_text_30832', 'Gene': 'KANSL1', 'topRSID': 'rs199533', 'p_GWAS': 1.293899e-08, 'b_GWAS': 0.0563}, {'UUID': 'NDD_SMR_genes_all_update_text_591214', 'Gene': 'KANSL1', 'topRSID': 'rs199525', 'p_GWAS': 1.346947e-08, 'b_GWAS': -0.0568}, {'UUID': 'NDD_SMR_genes_all_update_text_115205', 'Gene': 'KANSL1', 'topRSID': 'rs12150087', 'p_GWAS': 2.069835e-08, 'b_GWAS': -0.0555}, {'UUID': 'NDD_SMR_genes_all_update_text_115204', 'Gene': 'KANSL1', 'topRSID': 'rs12150087', 'p_GWAS': 2.069835e-08, 'b_GWAS': -0.0555}, {'UUID': 'NDD_SMR_genes_all_update_text_115200', 'Gene': 'KANSL1', 'topRSID': 'rs41374248', 'p_GWAS': 2.2468e-08, 'b_GWAS': -0.0548}, {'UUID': 'NDD_SMR_genes_all_update_text_115217', 'Gene': 'KANSL1', 'topRSID': 'rs62073098', 'p_GWAS': 3.106012e-08, 'b_GWAS': -0.0548}, {'UUID': 'NDD_SMR_genes_all_update_text_115216', 'Gene': 'KANSL1', 'topRSID': 'rs2668665', 'p_GWAS': 3.106012e-08, 'b_GWAS': -0.0548}, {'UUID': 'NDD_SMR_genes_all_update_text_115210', 'Gene': 'KANSL1', 'topRSID': 'rs2696610', 'p_GWAS': 3.29012e-08, 'b_GWAS': -0.0547}, {'UUID': 'NDD_SMR_genes_all_update_text_115213', 'Gene': 'KANSL1', 'topRSID': 'rs2532233', 'p_GWAS': 3.690625e-08, 'b_GWAS': -0.0545}, {'UUID': 'NDD_SMR_genes_all_update_text_115214', 'Gene': 'KANSL1', 'topRSID': 'rs2532233', 'p_GWAS': 3.690625e-08, 'b_GWAS': -0.0545}, {'UUID': 'NDD_SMR_genes_all_update_text_591218', 'Gene': 'KANSL1', 'topRSID': 'rs2532233', 'p_GWAS': 3.690625e-08, 'b_GWAS': -0.0545}, {'UUID': 'NDD_SMR_genes_all_update_text_591221', 'Gene': 'KANSL1', 'topRSID': 'rs62057144', 'p_GWAS': 3.910529e-08, 'b_GWAS': -0.0533}, {'UUID': 'NDD_SMR_genes_all_update_text_1610865', 'Gene': 'KANSL1', 'topRSID': 'rs2696673', 'p_GWAS': 4.243841e-08, 'b_GWAS': -0.0559}, {'UUID': 'NDD_SMR_genes_all_update_text_2657', 'Gene': 'KANSL1', 'topRSID': 'rs2732708', 'p_GWAS': 4.500356e-08, 'b_GWAS': 0.0547}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.193 | Q10 | Are there any SHANK2 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within SHANK2 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'SHANK2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1149 | Q10 | Are there any C10orf35 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within C10orf35 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'C10orf35' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1001 | Q10 | Are there any CTB-167G5.5 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within CTB-167G5.5 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'CTB-167G5.5' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1956 | Q10 | Are there any LRRK2 SNPs that have a statistically significant association with Parkinson's Disease? | Yes, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are at least 2 LRRK2 SNPs that are significantly associatied with Parkinson's Disease:
• rs1491942 (GWAS p-value: 7.52e-09; b-value: -0.1202)
• rs76904798 (GWAS p-value: 8.76e-09; b-value: 0.1352) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'LRRK2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_471471', 'Gene': 'LRRK2', 'topRSID': 'rs1491942', 'p_GWAS': 7.521466e-09, 'b_GWAS': -0.1202}, {'UUID': 'NDD_SMR_genes_all_update_text_1327039', 'Gene': 'LRRK2', 'topRSID': 'rs76904798', 'p_GWAS': 8.757419e-09, 'b_GWAS': 0.1352}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1657 | Q10 | Are there any SYT15 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within SYT15 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'SYT15' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.613 | Q10 | Are there any TIRAP SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within TIRAP that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'TIRAP' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.183 | Q10 | Are there any FAM132A SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within FAM132A that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'FAM132A' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.305 | Q10 | Are there any OBSCN SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within OBSCN that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'OBSCN' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.502 | Q10 | Are there any RP5-1029F21.3 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within RP5-1029F21.3 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'RP5-1029F21.3' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1696 | Q10 | Are there any APPBP2 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within APPBP2 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'APPBP2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1721 | Q10 | Are there any WBSCR17 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within WBSCR17 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'WBSCR17' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1662 | Q10 | Are there any ZC3H8 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within ZC3H8 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'ZC3H8' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1639 | Q10 | Are there any MRLN SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within MRLN that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'MRLN' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.523 | Q10 | Are there any LRRC37A17P SNPs that have a statistically significant association with Alzheimer's Disease? | Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there is at least 1 LRRC37A17P SNP that are significantly associatied with Alzheimer's Disease:
• rs62062294 (GWAS p-value: 2.12e-08; b-value: -0.0549) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'LRRC37A17P' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1203026', 'Gene': 'LRRC37A17P', 'topRSID': 'rs62062294', 'p_GWAS': 2.118427e-08, 'b_GWAS': -0.0549}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1985 | Q10 | Are there any PCDHA9 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within PCDHA9 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'PCDHA9' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1078 | Q10 | Are there any PAX6 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within PAX6 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'PAX6' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.482 | Q10 | Are there any CYGB SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within CYGB that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'CYGB' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.160 | Q10 | Are there any ATP6V1F SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within ATP6V1F that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'ATP6V1F' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1253 | Q10 | Are there any LINC00940 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within LINC00940 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'LINC00940' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1205 | Q10 | Are there any SIGLEC1 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within SIGLEC1 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'SIGLEC1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.17 | Q10 | Are there any WNT3 SNPs that have a statistically significant association with Parkinson's Disease? | Yes, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are at least 2 WNT3 SNPs that are significantly associatied with Parkinson's Disease:
• rs199523 (GWAS p-value: 9.68e-16; b-value: 0.1823)
• rs199520 (GWAS p-value: 8.38e-16; b-value: -0.1827) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'WNT3' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1564796', 'Gene': 'WNT3', 'topRSID': 'rs199520', 'p_GWAS': 8.384357e-16, 'b_GWAS': -0.1827}, {'UUID': 'NDD_SMR_genes_all_update_text_1328944', 'Gene': 'WNT3', 'topRSID': 'rs199523', 'p_GWAS': 9.68099e-16, 'b_GWAS': 0.1823}, {'UUID': 'NDD_SMR_genes_all_update_text_1370555', 'Gene': 'WNT3', 'topRSID': 'rs199523', 'p_GWAS': 9.68099e-16, 'b_GWAS': 0.1823}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1550 | Q10 | Are there any RUNX3 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within RUNX3 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'RUNX3' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1081 | Q10 | Are there any CD84 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within CD84 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'CD84' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1972 | Q10 | Are there any CTA-14H9.5 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within CTA-14H9.5 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'CTA-14H9.5' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.552 | Q10 | Are there any AHCTF1P1 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within AHCTF1P1 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'AHCTF1P1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1554 | Q10 | Are there any RUSC2 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within RUSC2 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'RUSC2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.