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Q40.229
Q40
Are there any specific alleles within the gene MIR210 associated with increased susceptibility to developing Progressive supranuclear palsy, as determined by significant SMR analysis?
No, based on the Whole Brain and Whole Blood samples tested, there are no alleles within the gene MIR210 that are significantly associated with an increased susceptibility to developing Progressive supranuclear palsy.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'MIR210' AND Disease = 'PSP' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.1699
Q40
Are there any specific alleles within the gene CXCL6 associated with increased susceptibility to developing Frontotemporal Dementia, as determined by significant SMR analysis?
No, based on the Whole Brain, Whole Blood and Tibial Nerve samples tested, there are no alleles within the gene CXCL6 that are significantly associated with an increased susceptibility to developing Frontotemporal Dementia.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'CXCL6' AND Disease = 'FTD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.1451
Q40
Are there any specific alleles within the gene IL18BP associated with increased susceptibility to developing Alzheimer's Disease, as determined by significant SMR analysis?
No, based on the Whole Blood, Cortex, Cerebellar Hemisphere, Tibial Nerve, Skeletal Muscle, Multi Ancestry Whole Brain and Cerebellum samples tested, there are no alleles within the gene IL18BP that are significantly associated with an increased susceptibility to developing Alzheimer's Disease.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'IL18BP' AND Disease = 'AD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.1976
Q40
Are there any specific alleles within the gene PHYHIP associated with increased susceptibility to developing Lewy Body Dementia, as determined by significant SMR analysis?
No, based on the Whole Brain, Whole Blood, Cerebellar Hemisphere, Multi Ancestry Whole Brain and Cerebellum samples tested, there are no alleles within the gene PHYHIP that are significantly associated with an increased susceptibility to developing Lewy Body Dementia.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'PHYHIP' AND Disease = 'LBD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.814
Q40
Are there any specific alleles within the gene FGF23 associated with increased susceptibility to developing Parkinson's Disease, as determined by significant SMR analysis?
No, based on the Whole Brain, Whole Blood, Cortex and Prefrontal Cortex samples tested, there are no alleles within the gene FGF23 that are significantly associated with an increased susceptibility to developing Parkinson's Disease.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'FGF23' AND Disease = 'PD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.1847
Q40
Are there any specific alleles within the gene RP11-347P5.1 associated with increased susceptibility to developing Alzheimer's Disease, as determined by significant SMR analysis?
No, based on the Tibial Nerve samples tested, there are no alleles within the gene RP11-347P5.1 that are significantly associated with an increased susceptibility to developing Alzheimer's Disease.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'RP11-347P5.1' AND Disease = 'AD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.151
Q40
Are there any specific alleles within the gene TMEM168 associated with increased susceptibility to developing Parkinson's Disease, as determined by significant SMR analysis?
No, based on the Whole Brain, Whole Blood, Multi Ancestry Whole Brain and Nucleus Accumbens Basal samples tested, there are no alleles within the gene TMEM168 that are significantly associated with an increased susceptibility to developing Parkinson's Disease.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'TMEM168' AND Disease = 'PD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.781
Q40
Are there any specific alleles within the gene ABCG2 associated with increased susceptibility to developing Frontotemporal Dementia, as determined by significant SMR analysis?
No, based on the Whole Brain and Whole Blood samples tested, there are no alleles within the gene ABCG2 that are significantly associated with an increased susceptibility to developing Frontotemporal Dementia.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'ABCG2' AND Disease = 'FTD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.727
Q40
Are there any specific alleles within the gene HVCN1 associated with increased susceptibility to developing Progressive supranuclear palsy, as determined by significant SMR analysis?
No, based on the Whole Blood samples tested, there are no alleles within the gene HVCN1 that are significantly associated with an increased susceptibility to developing Progressive supranuclear palsy.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'HVCN1' AND Disease = 'PSP' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.820
Q40
Are there any specific alleles within the gene EMC8 associated with increased susceptibility to developing Progressive supranuclear palsy, as determined by significant SMR analysis?
No, based on the Whole Brain and Whole Blood samples tested, there are no alleles within the gene EMC8 that are significantly associated with an increased susceptibility to developing Progressive supranuclear palsy.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'EMC8' AND Disease = 'PSP' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.1636
Q40
Are there any specific alleles within the gene RP11-613F22.7 associated with increased susceptibility to developing Alzheimer's Disease, as determined by significant SMR analysis?
No, based on the Prefrontal Cortex samples tested, there are no alleles within the gene RP11-613F22.7 that are significantly associated with an increased susceptibility to developing Alzheimer's Disease.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'RP11-613F22.7' AND Disease = 'AD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.825
Q40
Are there any specific alleles within the gene COL26A1 associated with increased susceptibility to developing Amyotrophic Lateral Sclerosis, as determined by significant SMR analysis?
No, based on the Cerebellum, Basal Ganglia, Whole Brain, Whole Blood, Cortex, Cerebellar Hemisphere, Caudate Basal Ganglia, Hypothalamus, Liver, Putamen Basal Ganglia and Nucleus Accumbens Basal samples tested, there are no alleles within the gene COL26A1 that are significantly associated with an increased susceptibili...
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'COL26A1' AND Disease = 'ALS' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.581
Q40
Are there any specific alleles within the gene MYLK4 associated with increased susceptibility to developing Lewy Body Dementia, as determined by significant SMR analysis?
No, based on the Cerebellum, Whole Brain, Whole Blood, Cortex, Frontal Cortex, Cerebellar Hemisphere, Prefrontal Cortex, Caudate Basal Ganglia, Tibial Nerve, Multi Ancestry Whole Brain, Hypothalamus, Liver, Putamen Basal Ganglia and Nucleus Accumbens Basal samples tested, there are no alleles within the gene MYLK4 that...
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'MYLK4' AND Disease = 'LBD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.563
Q40
Are there any specific alleles within the gene CXADR associated with increased susceptibility to developing Lewy Body Dementia, as determined by significant SMR analysis?
No, based on the Whole Brain, Whole Blood and Multi Ancestry Whole Brain samples tested, there are no alleles within the gene CXADR that are significantly associated with an increased susceptibility to developing Lewy Body Dementia.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'CXADR' AND Disease = 'LBD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.1758
Q40
Are there any specific alleles within the gene PYCR3 associated with increased susceptibility to developing Parkinson's Disease, as determined by significant SMR analysis?
No, based on the Cortex samples tested, there are no alleles within the gene PYCR3 that are significantly associated with an increased susceptibility to developing Parkinson's Disease.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'PYCR3' AND Disease = 'PD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.1727
Q40
Are there any specific alleles within the gene TMEM139 associated with increased susceptibility to developing Amyotrophic Lateral Sclerosis, as determined by significant SMR analysis?
No, based on the Tibial Nerve and Liver samples tested, there are no alleles within the gene TMEM139 that are significantly associated with an increased susceptibility to developing Amyotrophic Lateral Sclerosis.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'TMEM139' AND Disease = 'ALS' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.1349
Q40
Are there any specific alleles within the gene CTD-2184D3.7 associated with increased susceptibility to developing Progressive supranuclear palsy, as determined by significant SMR analysis?
No, based on the Whole Blood samples tested, there are no alleles within the gene CTD-2184D3.7 that are significantly associated with an increased susceptibility to developing Progressive supranuclear palsy.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'CTD-2184D3.7' AND Disease = 'PSP' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.1161
Q40
Are there any specific alleles within the gene RUSC1 associated with increased susceptibility to developing Progressive supranuclear palsy, as determined by significant SMR analysis?
No, based on the Tibial Nerve samples tested, there are no alleles within the gene RUSC1 that are significantly associated with an increased susceptibility to developing Progressive supranuclear palsy.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'RUSC1' AND Disease = 'PSP' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.945
Q40
Are there any specific alleles within the gene RN7SKP256 associated with increased susceptibility to developing Amyotrophic Lateral Sclerosis, as determined by significant SMR analysis?
No, based on the Prefrontal Cortex samples tested, there are no alleles within the gene RN7SKP256 that are significantly associated with an increased susceptibility to developing Amyotrophic Lateral Sclerosis.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'RN7SKP256' AND Disease = 'ALS' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.290
Q40
Are there any specific alleles within the gene RAB8B associated with increased susceptibility to developing Alzheimer's Disease, as determined by significant SMR analysis?
Yes, there are 2 alleles within the gene RAB8B that are significantly associated with an increased susceptibility to developing Alzheimer's Disease: • rs11858666 • Whole Brain: Adjusted SMR multi-SNP P-value: 3.45e-07; b: 1.1164e-01 • rs2729793 • Whole Blood: Adjusted SMR multi-SNP P-value: 4.97e-07; b: 8.5872e...
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'RAB8B' AND Disease = 'AD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
[{'UUID': 'NDD_SMR_genes_all_update_text_105698', 'Gene': 'RAB8B', 'Omic_tissue': 'Whole Brain', 'topSNP': 'rs11858666', 'A1': 'G', 'A2': 'C', 'Freq': 0.391616, 'p_SMR_multi': 3.453414e-07, 'Disease': 'AD', 'b_SMR': 0.111641, 'p_HEIDI': 0.7513961}, {'UUID': 'NDD_SMR_genes_all_update_text_646596', 'Gene': 'RAB8B', 'Omic...
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SMR Significance, Effect
Q40.1947
Q40
Are there any specific alleles within the gene TXK associated with increased susceptibility to developing Amyotrophic Lateral Sclerosis, as determined by significant SMR analysis?
No, based on the Whole Brain, Whole Blood and Cortex samples tested, there are no alleles within the gene TXK that are significantly associated with an increased susceptibility to developing Amyotrophic Lateral Sclerosis.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'TXK' AND Disease = 'ALS' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.973
Q40
Are there any specific alleles within the gene FBLN1 associated with increased susceptibility to developing Progressive supranuclear palsy, as determined by significant SMR analysis?
No, based on the Whole Brain, Whole Blood, Cortex and Multi Ancestry Whole Brain samples tested, there are no alleles within the gene FBLN1 that are significantly associated with an increased susceptibility to developing Progressive supranuclear palsy.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'FBLN1' AND Disease = 'PSP' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.605
Q40
Are there any specific alleles within the gene DISC1 associated with increased susceptibility to developing Frontotemporal Dementia, as determined by significant SMR analysis?
No, based on the Whole Brain, Whole Blood, Cortex, Prefrontal Cortex, Tibial Nerve, Skeletal Muscle and Multi Ancestry Whole Brain samples tested, there are no alleles within the gene DISC1 that are significantly associated with an increased susceptibility to developing Frontotemporal Dementia.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'DISC1' AND Disease = 'FTD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.1312
Q40
Are there any specific alleles within the gene RP11-405L18.4 associated with increased susceptibility to developing Progressive supranuclear palsy, as determined by significant SMR analysis?
No, based on the Tibial Nerve and Liver samples tested, there are no alleles within the gene RP11-405L18.4 that are significantly associated with an increased susceptibility to developing Progressive supranuclear palsy.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'RP11-405L18.4' AND Disease = 'PSP' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.1244
Q40
Are there any specific alleles within the gene AURKC associated with increased susceptibility to developing Progressive supranuclear palsy, as determined by significant SMR analysis?
No, based on the Cerebellum, Whole Brain, Whole Blood, Cortex, Multi Ancestry Whole Brain and Nucleus Accumbens Basal samples tested, there are no alleles within the gene AURKC that are significantly associated with an increased susceptibility to developing Progressive supranuclear palsy.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'AURKC' AND Disease = 'PSP' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.1638
Q40
Are there any specific alleles within the gene AC008753.4 associated with increased susceptibility to developing Progressive supranuclear palsy, as determined by significant SMR analysis?
No, based on the Whole Blood samples tested, there are no alleles within the gene AC008753.4 that are significantly associated with an increased susceptibility to developing Progressive supranuclear palsy.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'AC008753.4' AND Disease = 'PSP' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.1588
Q40
Are there any specific alleles within the gene EFCAB4B associated with increased susceptibility to developing Frontotemporal Dementia, as determined by significant SMR analysis?
No, based on the Whole Brain, Whole Blood, Tibial Nerve and Skeletal Muscle samples tested, there are no alleles within the gene EFCAB4B that are significantly associated with an increased susceptibility to developing Frontotemporal Dementia.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'EFCAB4B' AND Disease = 'FTD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.1316
Q40
Are there any specific alleles within the gene TALDO1 associated with increased susceptibility to developing Alzheimer's Disease, as determined by significant SMR analysis?
No, based on the Whole Brain, Whole Blood, Tibial Nerve and Multi Ancestry Whole Brain samples tested, there are no alleles within the gene TALDO1 that are significantly associated with an increased susceptibility to developing Alzheimer's Disease.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'TALDO1' AND Disease = 'AD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.1779
Q40
Are there any specific alleles within the gene TMEM163 associated with increased susceptibility to developing Parkinson's Disease, as determined by significant SMR analysis?
Yes, there are 2 alleles within the gene TMEM163 that are significantly associated with an increased susceptibility to developing Parkinson's Disease: • rs11684785 • Whole Blood: Adjusted SMR multi-SNP P-value: 1.30e-06; b: 2.4783e-01 • rs4440018 • Whole Blood: Adjusted SMR multi-SNP P-value: 2.94e-06; b: 1.000...
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'TMEM163' AND Disease = 'PD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
[{'UUID': 'NDD_SMR_genes_all_update_text_1554334', 'Gene': 'TMEM163', 'Omic_tissue': 'Whole Blood', 'topSNP': 'rs11684785', 'A1': 'G', 'A2': 'A', 'Freq': 0.428425, 'p_SMR_multi': 1.30336e-06, 'Disease': 'PD', 'b_SMR': 0.247832, 'p_HEIDI': 1.603795e-06}, {'UUID': 'NDD_SMR_genes_all_update_text_1019149', 'Gene': 'TMEM163...
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SMR Significance, Effect
Q40.1647
Q40
Are there any specific alleles within the gene RP11-1029J19.5 associated with increased susceptibility to developing Amyotrophic Lateral Sclerosis, as determined by significant SMR analysis?
No, based on the Whole Brain and Whole Blood samples tested, there are no alleles within the gene RP11-1029J19.5 that are significantly associated with an increased susceptibility to developing Amyotrophic Lateral Sclerosis.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'RP11-1029J19.5' AND Disease = 'ALS' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.1255
Q40
Are there any specific alleles within the gene GLB1L3 associated with increased susceptibility to developing Parkinson's Disease, as determined by significant SMR analysis?
No, based on the Cerebellum, Whole Brain, Whole Blood, Cerebellar Hemisphere and Prefrontal Cortex samples tested, there are no alleles within the gene GLB1L3 that are significantly associated with an increased susceptibility to developing Parkinson's Disease.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'GLB1L3' AND Disease = 'PD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.1675
Q40
Are there any specific alleles within the gene TARBP1 associated with increased susceptibility to developing Parkinson's Disease, as determined by significant SMR analysis?
No, based on the Whole Brain, Whole Blood and Skeletal Muscle samples tested, there are no alleles within the gene TARBP1 that are significantly associated with an increased susceptibility to developing Parkinson's Disease.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'TARBP1' AND Disease = 'PD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.1801
Q40
Are there any specific alleles within the gene GCA associated with increased susceptibility to developing Amyotrophic Lateral Sclerosis, as determined by significant SMR analysis?
No, based on the Cerebellum, Cerebellar Hemisphere, Prefrontal Cortex, Multi Ancestry Whole Brain and Whole Blood samples tested, there are no alleles within the gene GCA that are significantly associated with an increased susceptibility to developing Amyotrophic Lateral Sclerosis.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'GCA' AND Disease = 'ALS' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.759
Q40
Are there any specific alleles within the gene STK3 associated with increased susceptibility to developing Parkinson's Disease, as determined by significant SMR analysis?
No, based on the Whole Brain, Whole Blood, Cortex and Multi Ancestry Whole Brain samples tested, there are no alleles within the gene STK3 that are significantly associated with an increased susceptibility to developing Parkinson's Disease.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'STK3' AND Disease = 'PD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.616
Q40
Are there any specific alleles within the gene RNF43 associated with increased susceptibility to developing Lewy Body Dementia, as determined by significant SMR analysis?
No, based on the Whole Brain, Multi Ancestry Whole Brain and Whole Blood samples tested, there are no alleles within the gene RNF43 that are significantly associated with an increased susceptibility to developing Lewy Body Dementia.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'RNF43' AND Disease = 'LBD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.1045
Q40
Are there any specific alleles within the gene LEF1 associated with increased susceptibility to developing Frontotemporal Dementia, as determined by significant SMR analysis?
No, based on the Whole Blood samples tested, there are no alleles within the gene LEF1 that are significantly associated with an increased susceptibility to developing Frontotemporal Dementia.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'LEF1' AND Disease = 'FTD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.788
Q40
Are there any specific alleles within the gene SNORA24 associated with increased susceptibility to developing Alzheimer's Disease, as determined by significant SMR analysis?
No, based on the Whole Brain and Whole Blood samples tested, there are no alleles within the gene SNORA24 that are significantly associated with an increased susceptibility to developing Alzheimer's Disease.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'SNORA24' AND Disease = 'AD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.1690
Q40
Are there any specific alleles within the gene ZNRF2P2 associated with increased susceptibility to developing Alzheimer's Disease, as determined by significant SMR analysis?
No, based on the Whole Brain, Whole Blood, Prefrontal Cortex, Cortex, Skeletal Muscle, Hippocampus, Substantia nigra and Hypothalamus samples tested, there are no alleles within the gene ZNRF2P2 that are significantly associated with an increased susceptibility to developing Alzheimer's Disease.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'ZNRF2P2' AND Disease = 'AD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.997
Q40
Are there any specific alleles within the gene PPP2R1A associated with increased susceptibility to developing Frontotemporal Dementia, as determined by significant SMR analysis?
No, based on the Whole Brain, Whole Blood, Tibial Nerve and Skeletal Muscle samples tested, there are no alleles within the gene PPP2R1A that are significantly associated with an increased susceptibility to developing Frontotemporal Dementia.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'PPP2R1A' AND Disease = 'FTD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.499
Q40
Are there any specific alleles within the gene ELK1P1 associated with increased susceptibility to developing Frontotemporal Dementia, as determined by significant SMR analysis?
No, based on the Whole Brain and Whole Blood samples tested, there are no alleles within the gene ELK1P1 that are significantly associated with an increased susceptibility to developing Frontotemporal Dementia.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'ELK1P1' AND Disease = 'FTD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.1320
Q40
Are there any specific alleles within the gene SPPL2C associated with increased susceptibility to developing Progressive supranuclear palsy, as determined by significant SMR analysis?
Yes, there are 2 alleles within the gene SPPL2C that are significantly associated with an increased susceptibility to developing Progressive supranuclear palsy: • rs393152 • Cerebellum: Adjusted SMR multi-SNP P-value: 1.26e-19; b: 1.9899e+00 • Cortex: Adjusted SMR multi-SNP P-value: 2.37e-14; b: 6.0111e+00 • rs...
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'SPPL2C' AND Disease = 'PSP' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
[{'UUID': 'NDD_SMR_genes_all_update_text_22216', 'Gene': 'SPPL2C', 'Omic_tissue': 'Cerebellum', 'topSNP': '17:45641777:rs393152:A_G', 'A1': 'A', 'A2': 'G', 'Freq': 0.762781, 'p_SMR_multi': 1.259583e-19, 'Disease': 'PSP', 'b_SMR': 1.98993, 'p_HEIDI': 4.385134e-16}, {'UUID': 'NDD_SMR_genes_all_update_text_1714154', 'Gene...
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SMR Significance, Effect
Q40.281
Q40
Are there any specific alleles within the gene CD58 associated with increased susceptibility to developing Lewy Body Dementia, as determined by significant SMR analysis?
No, based on the Whole Brain and Whole Blood samples tested, there are no alleles within the gene CD58 that are significantly associated with an increased susceptibility to developing Lewy Body Dementia.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'CD58' AND Disease = 'LBD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.1848
Q40
Are there any specific alleles within the gene RP11-321E8.5 associated with increased susceptibility to developing Parkinson's Disease, as determined by significant SMR analysis?
No, based on the Prefrontal Cortex, Tibial Nerve and Cerebellum samples tested, there are no alleles within the gene RP11-321E8.5 that are significantly associated with an increased susceptibility to developing Parkinson's Disease.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'RP11-321E8.5' AND Disease = 'PD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.363
Q40
Are there any specific alleles within the gene RP11-77H9.8 associated with increased susceptibility to developing Parkinson's Disease, as determined by significant SMR analysis?
No, based on the Skeletal Muscle samples tested, there are no alleles within the gene RP11-77H9.8 that are significantly associated with an increased susceptibility to developing Parkinson's Disease.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'RP11-77H9.8' AND Disease = 'PD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.1179
Q40
Are there any specific alleles within the gene TMEM221 associated with increased susceptibility to developing Lewy Body Dementia, as determined by significant SMR analysis?
No, based on the Tibial Nerve, Skeletal Muscle and Whole Blood samples tested, there are no alleles within the gene TMEM221 that are significantly associated with an increased susceptibility to developing Lewy Body Dementia.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'TMEM221' AND Disease = 'LBD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.239
Q40
Are there any specific alleles within the gene THA1P associated with increased susceptibility to developing Parkinson's Disease, as determined by significant SMR analysis?
No, based on the Whole Brain, Whole Blood and Cerebellar Hemisphere samples tested, there are no alleles within the gene THA1P that are significantly associated with an increased susceptibility to developing Parkinson's Disease.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'THA1P' AND Disease = 'PD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.557
Q40
Are there any specific alleles within the gene RP11-408E5.4 associated with increased susceptibility to developing Frontotemporal Dementia, as determined by significant SMR analysis?
No, based on the Whole Blood samples tested, there are no alleles within the gene RP11-408E5.4 that are significantly associated with an increased susceptibility to developing Frontotemporal Dementia.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'RP11-408E5.4' AND Disease = 'FTD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.1870
Q40
Are there any specific alleles within the gene CTD-2126E3.1 associated with increased susceptibility to developing Amyotrophic Lateral Sclerosis, as determined by significant SMR analysis?
No, based on the Whole Brain, Tibial Nerve and Skeletal Muscle samples tested, there are no alleles within the gene CTD-2126E3.1 that are significantly associated with an increased susceptibility to developing Amyotrophic Lateral Sclerosis.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'CTD-2126E3.1' AND Disease = 'ALS' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.1915
Q40
Are there any specific alleles within the gene CCDC74B associated with increased susceptibility to developing Frontotemporal Dementia, as determined by significant SMR analysis?
No, based on the Cerebellum, Whole Brain, Whole Blood, Cortex, Cerebellar Hemisphere, Prefrontal Cortex, Skeletal Muscle, Multi Ancestry Whole Brain and Anterior Cingulate Cortex BA24 samples tested, there are no alleles within the gene CCDC74B that are significantly associated with an increased susceptibility to devel...
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'CCDC74B' AND Disease = 'FTD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.211
Q40
Are there any specific alleles within the gene EPDR1 associated with increased susceptibility to developing Alzheimer's Disease, as determined by significant SMR analysis?
Yes, there is 1 allele within the gene EPDR1 that is significantly associated with an increased susceptibility to developing Alzheimer's Disease: • rs4723717 • Whole Blood: Adjusted SMR multi-SNP P-value: 1.78e-06; b: 2.3331e-02
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'EPDR1' AND Disease = 'AD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
[{'UUID': 'NDD_SMR_genes_all_update_text_1495506', 'Gene': 'EPDR1', 'Omic_tissue': 'Whole Blood', 'topSNP': 'rs4723717', 'A1': 'G', 'A2': 'A', 'Freq': 0.238241, 'p_SMR_multi': 1.782941e-06, 'Disease': 'AD', 'b_SMR': 0.0233313, 'p_HEIDI': 0.9830444}]
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SMR Significance, Effect
Q40.1922
Q40
Are there any specific alleles within the gene NUFIP2 associated with increased susceptibility to developing Progressive supranuclear palsy, as determined by significant SMR analysis?
No, based on the Whole Brain, Whole Blood and Multi Ancestry Whole Brain samples tested, there are no alleles within the gene NUFIP2 that are significantly associated with an increased susceptibility to developing Progressive supranuclear palsy.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'NUFIP2' AND Disease = 'PSP' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.1561
Q40
Are there any specific alleles within the gene PTPN20B associated with increased susceptibility to developing Frontotemporal Dementia, as determined by significant SMR analysis?
No, based on the Whole Blood and Prefrontal Cortex samples tested, there are no alleles within the gene PTPN20B that are significantly associated with an increased susceptibility to developing Frontotemporal Dementia.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'PTPN20B' AND Disease = 'FTD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.60
Q40
Are there any specific alleles within the gene JPH1 associated with increased susceptibility to developing Lewy Body Dementia, as determined by significant SMR analysis?
No, based on the Spinalcord, Cortex, Prefrontal Cortex, Tibial Nerve, Hippocampus, Multi Ancestry Whole Brain and Substantia nigra samples tested, there are no alleles within the gene JPH1 that are significantly associated with an increased susceptibility to developing Lewy Body Dementia.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'JPH1' AND Disease = 'LBD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.1835
Q40
Are there any specific alleles within the gene RBAK-RBAKDN associated with increased susceptibility to developing Parkinson's Disease, as determined by significant SMR analysis?
No, based on the Whole Brain and Whole Blood samples tested, there are no alleles within the gene RBAK-RBAKDN that are significantly associated with an increased susceptibility to developing Parkinson's Disease.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'RBAK-RBAKDN' AND Disease = 'PD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.1906
Q40
Are there any specific alleles within the gene ARHGAP27 associated with increased susceptibility to developing Progressive supranuclear palsy, as determined by significant SMR analysis?
Yes, there are 4 alleles within the gene ARHGAP27 that are significantly associated with an increased susceptibility to developing Progressive supranuclear palsy: • rs11012 • Whole Blood: Adjusted SMR multi-SNP P-value: 1.38e-39; b: 1.2425e+00 • Multi Ancestry Whole Brain: Adjusted SMR multi-SNP P-value: 9.17e-...
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'ARHGAP27' AND Disease = 'PSP' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
[{'UUID': 'NDD_SMR_genes_all_update_text_1041713', 'Gene': 'ARHGAP27', 'Omic_tissue': 'Whole Blood', 'topSNP': 'rs11012', 'A1': 'T', 'A2': 'C', 'Freq': 0.191207, 'p_SMR_multi': 1.378348e-39, 'Disease': 'PSP', 'b_SMR': 1.24252, 'p_HEIDI': 8.450584e-08}, {'UUID': 'NDD_SMR_genes_all_update_text_1444267', 'Gene': 'ARHGAP27...
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SMR Significance, Effect
Q40.1578
Q40
Are there any specific alleles within the gene ZNF749 associated with increased susceptibility to developing Parkinson's Disease, as determined by significant SMR analysis?
No, based on the Cerebellum, Basal Ganglia, Cortex, Frontal Cortex, Cerebellar Hemisphere, Prefrontal Cortex, Caudate Basal Ganglia, Tibial Nerve, Skeletal Muscle, Hippocampus, Multi Ancestry Whole Brain, Substantia nigra, Hypothalamus, Liver, Anterior Cingulate Cortex BA24, Putamen Basal Ganglia, Amygdala, Whole Brain...
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'ZNF749' AND Disease = 'PD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.368
Q40
Are there any specific alleles within the gene WAC-AS1 associated with increased susceptibility to developing Progressive supranuclear palsy, as determined by significant SMR analysis?
No, based on the Whole Blood, Frontal Cortex, Cerebellar Hemisphere, Cortex, Tibial Nerve, Skeletal Muscle, Multi Ancestry Whole Brain, Liver, Putamen Basal Ganglia, Whole Brain and Cerebellum samples tested, there are no alleles within the gene WAC-AS1 that are significantly associated with an increased susceptibility...
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'WAC-AS1' AND Disease = 'PSP' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.511
Q40
Are there any specific alleles within the gene RP3-395M20.9 associated with increased susceptibility to developing Frontotemporal Dementia, as determined by significant SMR analysis?
No, based on the Cerebellar Hemisphere, Tibial Nerve, Whole Blood and Cerebellum samples tested, there are no alleles within the gene RP3-395M20.9 that are significantly associated with an increased susceptibility to developing Frontotemporal Dementia.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'RP3-395M20.9' AND Disease = 'FTD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.815
Q40
Are there any specific alleles within the gene MAN1A2 associated with increased susceptibility to developing Progressive supranuclear palsy, as determined by significant SMR analysis?
No, based on the Whole Brain, Whole Blood, Tibial Nerve, Skeletal Muscle and Multi Ancestry Whole Brain samples tested, there are no alleles within the gene MAN1A2 that are significantly associated with an increased susceptibility to developing Progressive supranuclear palsy.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'MAN1A2' AND Disease = 'PSP' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.1122
Q40
Are there any specific alleles within the gene CKM associated with increased susceptibility to developing Alzheimer's Disease, as determined by significant SMR analysis?
Yes, there is 1 allele within the gene CKM that is significantly associated with an increased susceptibility to developing Alzheimer's Disease: • rs386569 • Whole Blood: Adjusted SMR multi-SNP P-value: 2.61e-08; b: 1.1944e-01
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'CKM' AND Disease = 'AD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
[{'UUID': 'NDD_SMR_genes_all_update_text_1503918', 'Gene': 'CKM', 'Omic_tissue': 'Whole Blood', 'topSNP': 'rs386569', 'A1': 'G', 'A2': 'A', 'Freq': 0.321063, 'p_SMR_multi': 2.608329e-08, 'Disease': 'AD', 'b_SMR': 0.119442, 'p_HEIDI': 0.021922}]
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SMR Significance, Effect
Q40.1731
Q40
Are there any specific alleles within the gene LRRC37A associated with increased susceptibility to developing Progressive supranuclear palsy, as determined by significant SMR analysis?
Yes, there are 4 alleles within the gene LRRC37A that are significantly associated with an increased susceptibility to developing Progressive supranuclear palsy: • rs7225002 • Cortex: Adjusted SMR multi-SNP P-value: 3.50e-38; b: 4.5126e-01 • Tibial Nerve: Adjusted SMR multi-SNP P-value: 7.64e-21; b: 4.5235e-01 ...
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'LRRC37A' AND Disease = 'PSP' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
[{'UUID': 'NDD_SMR_genes_all_update_text_1154398', 'Gene': 'LRRC37A', 'Omic_tissue': 'Cortex', 'topSNP': '17:46111701:rs7225002:G_A', 'A1': 'A', 'A2': 'G', 'Freq': 0.564417, 'p_SMR_multi': 3.495026e-38, 'Disease': 'PSP', 'b_SMR': 0.451261, 'p_HEIDI': 6.511525e-33}, {'UUID': 'NDD_SMR_genes_all_update_text_1444274', 'Gen...
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SMR Significance, Effect
Q40.1216
Q40
Are there any specific alleles within the gene VASH1 associated with increased susceptibility to developing Amyotrophic Lateral Sclerosis, as determined by significant SMR analysis?
No, based on the Whole Brain, Whole Blood, Tibial Nerve, Skeletal Muscle and Multi Ancestry Whole Brain samples tested, there are no alleles within the gene VASH1 that are significantly associated with an increased susceptibility to developing Amyotrophic Lateral Sclerosis.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'VASH1' AND Disease = 'ALS' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.1212
Q40
Are there any specific alleles within the gene CSRNP2 associated with increased susceptibility to developing Progressive supranuclear palsy, as determined by significant SMR analysis?
No, based on the Cerebellum, Whole Brain, Whole Blood, Cerebellar Hemisphere and Multi Ancestry Whole Brain samples tested, there are no alleles within the gene CSRNP2 that are significantly associated with an increased susceptibility to developing Progressive supranuclear palsy.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'CSRNP2' AND Disease = 'PSP' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.971
Q40
Are there any specific alleles within the gene RP11-801F7.1 associated with increased susceptibility to developing Frontotemporal Dementia, as determined by significant SMR analysis?
No, based on the Prefrontal Cortex samples tested, there are no alleles within the gene RP11-801F7.1 that are significantly associated with an increased susceptibility to developing Frontotemporal Dementia.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'RP11-801F7.1' AND Disease = 'FTD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.805
Q40
Are there any specific alleles within the gene NPHS2 associated with increased susceptibility to developing Alzheimer's Disease, as determined by significant SMR analysis?
No, based on the Whole Brain and Whole Blood samples tested, there are no alleles within the gene NPHS2 that are significantly associated with an increased susceptibility to developing Alzheimer's Disease.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'NPHS2' AND Disease = 'AD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.121
Q40
Are there any specific alleles within the gene UBXN6 associated with increased susceptibility to developing Parkinson's Disease, as determined by significant SMR analysis?
No, based on the Spinalcord, Whole Brain, Whole Blood, Cortex, Frontal Cortex, Prefrontal Cortex, Caudate Basal Ganglia, Tibial Nerve, Skeletal Muscle, Hippocampus, Multi Ancestry Whole Brain, Hypothalamus, Anterior Cingulate Cortex BA24, Amygdala and Cerebellum samples tested, there are no alleles within the gene UBXN...
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'UBXN6' AND Disease = 'PD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.1322
Q40
Are there any specific alleles within the gene NUDT16P1 associated with increased susceptibility to developing Frontotemporal Dementia, as determined by significant SMR analysis?
No, based on the Whole Brain, Multi Ancestry Whole Brain and Whole Blood samples tested, there are no alleles within the gene NUDT16P1 that are significantly associated with an increased susceptibility to developing Frontotemporal Dementia.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'NUDT16P1' AND Disease = 'FTD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.1221
Q40
Are there any specific alleles within the gene RP11-473O4.3 associated with increased susceptibility to developing Amyotrophic Lateral Sclerosis, as determined by significant SMR analysis?
No, based on the Whole Blood samples tested, there are no alleles within the gene RP11-473O4.3 that are significantly associated with an increased susceptibility to developing Amyotrophic Lateral Sclerosis.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'RP11-473O4.3' AND Disease = 'ALS' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.528
Q40
Are there any specific alleles within the gene RP11-412D9.4 associated with increased susceptibility to developing Lewy Body Dementia, as determined by significant SMR analysis?
No, based on the Whole Brain, Whole Blood, Tibial Nerve, Skeletal Muscle and Multi Ancestry Whole Brain samples tested, there are no alleles within the gene RP11-412D9.4 that are significantly associated with an increased susceptibility to developing Lewy Body Dementia.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'RP11-412D9.4' AND Disease = 'LBD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.519
Q40
Are there any specific alleles within the gene KLRD1 associated with increased susceptibility to developing Alzheimer's Disease, as determined by significant SMR analysis?
No, based on the Whole Blood, Cortex, Prefrontal Cortex, Tibial Nerve, Skeletal Muscle and Nucleus Accumbens Basal samples tested, there are no alleles within the gene KLRD1 that are significantly associated with an increased susceptibility to developing Alzheimer's Disease.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'KLRD1' AND Disease = 'AD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.84
Q40
Are there any specific alleles within the gene RP11-404F10.2 associated with increased susceptibility to developing Lewy Body Dementia, as determined by significant SMR analysis?
No, based on the Whole Blood samples tested, there are no alleles within the gene RP11-404F10.2 that are significantly associated with an increased susceptibility to developing Lewy Body Dementia.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'RP11-404F10.2' AND Disease = 'LBD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.717
Q40
Are there any specific alleles within the gene PICALM associated with increased susceptibility to developing Alzheimer's Disease, as determined by significant SMR analysis?
Yes, there are 2 alleles within the gene PICALM that are significantly associated with an increased susceptibility to developing Alzheimer's Disease: • rs7131120 • Whole Blood: Adjusted SMR multi-SNP P-value: 5.34e-09; b: 2.0462e-01 • rs604767 • Whole Blood: Adjusted SMR multi-SNP P-value: 2.34e-07; b: 2.6360e-...
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'PICALM' AND Disease = 'AD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
[{'UUID': 'NDD_SMR_genes_all_update_text_1498580', 'Gene': 'PICALM', 'Omic_tissue': 'Whole Blood', 'topSNP': 'rs7131120', 'A1': 'G', 'A2': 'C', 'Freq': 0.217791, 'p_SMR_multi': 5.340866e-09, 'Disease': 'AD', 'b_SMR': 0.204624, 'p_HEIDI': 4.21145e-08}, {'UUID': 'NDD_SMR_genes_all_update_text_610282', 'Gene': 'PICALM', '...
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SMR Significance, Effect
Q40.1185
Q40
Are there any specific alleles within the gene FBXW5 associated with increased susceptibility to developing Alzheimer's Disease, as determined by significant SMR analysis?
No, based on the Whole Brain and Whole Blood samples tested, there are no alleles within the gene FBXW5 that are significantly associated with an increased susceptibility to developing Alzheimer's Disease.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'FBXW5' AND Disease = 'AD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.386
Q40
Are there any specific alleles within the gene FZD9 associated with increased susceptibility to developing Lewy Body Dementia, as determined by significant SMR analysis?
No, based on the Whole Brain, Whole Blood, Cortex and Tibial Nerve samples tested, there are no alleles within the gene FZD9 that are significantly associated with an increased susceptibility to developing Lewy Body Dementia.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'FZD9' AND Disease = 'LBD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.1022
Q40
Are there any specific alleles within the gene SRL associated with increased susceptibility to developing Frontotemporal Dementia, as determined by significant SMR analysis?
No, based on the Whole Brain, Whole Blood, Cortex, Skeletal Muscle and Multi Ancestry Whole Brain samples tested, there are no alleles within the gene SRL that are significantly associated with an increased susceptibility to developing Frontotemporal Dementia.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'SRL' AND Disease = 'FTD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.1689
Q40
Are there any specific alleles within the gene TRIP11 associated with increased susceptibility to developing Parkinson's Disease, as determined by significant SMR analysis?
No, based on the Whole Brain, Tibial Nerve, Skeletal Muscle, Multi Ancestry Whole Brain, Whole Blood and Cerebellum samples tested, there are no alleles within the gene TRIP11 that are significantly associated with an increased susceptibility to developing Parkinson's Disease.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'TRIP11' AND Disease = 'PD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.87
Q40
Are there any specific alleles within the gene KB-1639H6.2 associated with increased susceptibility to developing Progressive supranuclear palsy, as determined by significant SMR analysis?
No, based on the Whole Blood samples tested, there are no alleles within the gene KB-1639H6.2 that are significantly associated with an increased susceptibility to developing Progressive supranuclear palsy.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'KB-1639H6.2' AND Disease = 'PSP' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.1684
Q40
Are there any specific alleles within the gene LHX9 associated with increased susceptibility to developing Parkinson's Disease, as determined by significant SMR analysis?
No, based on the Whole Brain, Whole Blood, Cortex and Liver samples tested, there are no alleles within the gene LHX9 that are significantly associated with an increased susceptibility to developing Parkinson's Disease.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'LHX9' AND Disease = 'PD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.333
Q40
Are there any specific alleles within the gene ADCK5 associated with increased susceptibility to developing Alzheimer's Disease, as determined by significant SMR analysis?
No, based on the Whole Brain, Whole Blood and Multi Ancestry Whole Brain samples tested, there are no alleles within the gene ADCK5 that are significantly associated with an increased susceptibility to developing Alzheimer's Disease.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'ADCK5' AND Disease = 'AD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.7
Q40
Are there any specific alleles within the gene AC009336.24 associated with increased susceptibility to developing Alzheimer's Disease, as determined by significant SMR analysis?
No, based on the Whole Brain, Whole Blood, Prefrontal Cortex, Tibial Nerve, Hippocampus and Putamen Basal Ganglia samples tested, there are no alleles within the gene AC009336.24 that are significantly associated with an increased susceptibility to developing Alzheimer's Disease.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'AC009336.24' AND Disease = 'AD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.737
Q40
Are there any specific alleles within the gene GOLGA5 associated with increased susceptibility to developing Alzheimer's Disease, as determined by significant SMR analysis?
No, based on the Whole Brain, Whole Blood and Multi Ancestry Whole Brain samples tested, there are no alleles within the gene GOLGA5 that are significantly associated with an increased susceptibility to developing Alzheimer's Disease.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'GOLGA5' AND Disease = 'AD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.750
Q40
Are there any specific alleles within the gene LOC441046 associated with increased susceptibility to developing Amyotrophic Lateral Sclerosis, as determined by significant SMR analysis?
No, based on the Whole Brain and Whole Blood samples tested, there are no alleles within the gene LOC441046 that are significantly associated with an increased susceptibility to developing Amyotrophic Lateral Sclerosis.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'LOC441046' AND Disease = 'ALS' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.1414
Q40
Are there any specific alleles within the gene AC006369.2 associated with increased susceptibility to developing Parkinson's Disease, as determined by significant SMR analysis?
No, based on the Whole Brain and Whole Blood samples tested, there are no alleles within the gene AC006369.2 that are significantly associated with an increased susceptibility to developing Parkinson's Disease.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'AC006369.2' AND Disease = 'PD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.1751
Q40
Are there any specific alleles within the gene HOXA4 associated with increased susceptibility to developing Parkinson's Disease, as determined by significant SMR analysis?
No, based on the Tibial Nerve and Whole Blood samples tested, there are no alleles within the gene HOXA4 that are significantly associated with an increased susceptibility to developing Parkinson's Disease.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'HOXA4' AND Disease = 'PD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.457
Q40
Are there any specific alleles within the gene CUTA associated with increased susceptibility to developing Alzheimer's Disease, as determined by significant SMR analysis?
No, based on the Whole Brain, Whole Blood, Prefrontal Cortex, Tibial Nerve and Skeletal Muscle samples tested, there are no alleles within the gene CUTA that are significantly associated with an increased susceptibility to developing Alzheimer's Disease.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'CUTA' AND Disease = 'AD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.496
Q40
Are there any specific alleles within the gene MBNL2 associated with increased susceptibility to developing Progressive supranuclear palsy, as determined by significant SMR analysis?
No, based on the Whole Brain, Whole Blood and Tibial Nerve samples tested, there are no alleles within the gene MBNL2 that are significantly associated with an increased susceptibility to developing Progressive supranuclear palsy.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'MBNL2' AND Disease = 'PSP' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.1482
Q40
Are there any specific alleles within the gene SLC52A3 associated with increased susceptibility to developing Lewy Body Dementia, as determined by significant SMR analysis?
No, based on the Whole Brain, Whole Blood and Multi Ancestry Whole Brain samples tested, there are no alleles within the gene SLC52A3 that are significantly associated with an increased susceptibility to developing Lewy Body Dementia.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'SLC52A3' AND Disease = 'LBD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.291
Q40
Are there any specific alleles within the gene RP11-94P11.4 associated with increased susceptibility to developing Frontotemporal Dementia, as determined by significant SMR analysis?
No, based on the Whole Blood samples tested, there are no alleles within the gene RP11-94P11.4 that are significantly associated with an increased susceptibility to developing Frontotemporal Dementia.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'RP11-94P11.4' AND Disease = 'FTD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.1817
Q40
Are there any specific alleles within the gene NAGS associated with increased susceptibility to developing Alzheimer's Disease, as determined by significant SMR analysis?
No, based on the Cerebellum, Whole Brain, Whole Blood, Cortex, Prefrontal Cortex, Caudate Basal Ganglia, Tibial Nerve and Multi Ancestry Whole Brain samples tested, there are no alleles within the gene NAGS that are significantly associated with an increased susceptibility to developing Alzheimer's Disease.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'NAGS' AND Disease = 'AD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.1986
Q40
Are there any specific alleles within the gene STX1B associated with increased susceptibility to developing Parkinson's Disease, as determined by significant SMR analysis?
Yes, there is 1 allele within the gene STX1B that is significantly associated with an increased susceptibility to developing Parkinson's Disease: • rs35961830 • Whole Blood: Adjusted SMR multi-SNP P-value: 1.40e-06; b: 3.5357e-01
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'STX1B' AND Disease = 'PD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
[{'UUID': 'NDD_SMR_genes_all_update_text_974674', 'Gene': 'STX1B', 'Omic_tissue': 'Whole Blood', 'topSNP': 'rs35961830', 'A1': 'C', 'A2': 'T', 'Freq': 0.366053, 'p_SMR_multi': 1.400111e-06, 'Disease': 'PD', 'b_SMR': 0.353566, 'p_HEIDI': 0.009613103}]
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SMR Significance, Effect
Q40.1370
Q40
Are there any specific alleles within the gene FGA associated with increased susceptibility to developing Progressive supranuclear palsy, as determined by significant SMR analysis?
No, based on the Whole Blood samples tested, there are no alleles within the gene FGA that are significantly associated with an increased susceptibility to developing Progressive supranuclear palsy.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'FGA' AND Disease = 'PSP' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.893
Q40
Are there any specific alleles within the gene MED6P1 associated with increased susceptibility to developing Amyotrophic Lateral Sclerosis, as determined by significant SMR analysis?
No, based on the Whole Blood samples tested, there are no alleles within the gene MED6P1 that are significantly associated with an increased susceptibility to developing Amyotrophic Lateral Sclerosis.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'MED6P1' AND Disease = 'ALS' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.1063
Q40
Are there any specific alleles within the gene LOC285796 associated with increased susceptibility to developing Frontotemporal Dementia, as determined by significant SMR analysis?
No, based on the Whole Blood samples tested, there are no alleles within the gene LOC285796 that are significantly associated with an increased susceptibility to developing Frontotemporal Dementia.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'LOC285796' AND Disease = 'FTD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.1846
Q40
Are there any specific alleles within the gene RP11-625L16.1 associated with increased susceptibility to developing Parkinson's Disease, as determined by significant SMR analysis?
No, based on the Whole Brain samples tested, there are no alleles within the gene RP11-625L16.1 that are significantly associated with an increased susceptibility to developing Parkinson's Disease.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'RP11-625L16.1' AND Disease = 'PD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.1982
Q40
Are there any specific alleles within the gene PPIAP29 associated with increased susceptibility to developing Alzheimer's Disease, as determined by significant SMR analysis?
No, based on the Whole Blood samples tested, there are no alleles within the gene PPIAP29 that are significantly associated with an increased susceptibility to developing Alzheimer's Disease.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'PPIAP29' AND Disease = 'AD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.789
Q40
Are there any specific alleles within the gene GM2A associated with increased susceptibility to developing Progressive supranuclear palsy, as determined by significant SMR analysis?
No, based on the Whole Blood, Cortex, Tibial Nerve, Skeletal Muscle and Multi Ancestry Whole Brain samples tested, there are no alleles within the gene GM2A that are significantly associated with an increased susceptibility to developing Progressive supranuclear palsy.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'GM2A' AND Disease = 'PSP' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.866
Q40
Are there any specific alleles within the gene RP11-467L13.5 associated with increased susceptibility to developing Lewy Body Dementia, as determined by significant SMR analysis?
No, based on the Whole Blood samples tested, there are no alleles within the gene RP11-467L13.5 that are significantly associated with an increased susceptibility to developing Lewy Body Dementia.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'RP11-467L13.5' AND Disease = 'LBD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.1306
Q40
Are there any specific alleles within the gene RP5-827C21.4 associated with increased susceptibility to developing Lewy Body Dementia, as determined by significant SMR analysis?
No, based on the Cortex, Tibial Nerve, Skeletal Muscle, Multi Ancestry Whole Brain, Liver, Whole Blood, Whole Brain and Cerebellum samples tested, there are no alleles within the gene RP5-827C21.4 that are significantly associated with an increased susceptibility to developing Lewy Body Dementia.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'RP5-827C21.4' AND Disease = 'LBD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.1088
Q40
Are there any specific alleles within the gene THSD7A associated with increased susceptibility to developing Frontotemporal Dementia, as determined by significant SMR analysis?
No, based on the Whole Brain, Whole Blood, Cortex, Prefrontal Cortex, Tibial Nerve and Multi Ancestry Whole Brain samples tested, there are no alleles within the gene THSD7A that are significantly associated with an increased susceptibility to developing Frontotemporal Dementia.
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'THSD7A' AND Disease = 'FTD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
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SMR Significance, Effect
Q40.1889
Q40
Are there any specific alleles within the gene GPX4 associated with increased susceptibility to developing Alzheimer's Disease, as determined by significant SMR analysis?
Yes, there is 1 allele within the gene GPX4 that is significantly associated with an increased susceptibility to developing Alzheimer's Disease: • rs8103188 • Whole Blood: Adjusted SMR multi-SNP P-value: 6.03e-13; b: 4.8419e-02
SELECT UUID, Gene, Omic_tissue, topSNP, A1, A2, Freq, p_SMR_multi, Disease, b_SMR, p_HEIDI FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Gene = 'GPX4' AND Disease = 'AD' AND p_SMR_multi < 2.95e-6 AND b_SMR > 0 ORDER BY p_SMR_multi LIMIT 100
[{'UUID': 'NDD_SMR_genes_all_update_text_1503135', 'Gene': 'GPX4', 'Omic_tissue': 'Whole Blood', 'topSNP': 'rs8103188', 'A1': 'G', 'A2': 'A', 'Freq': 0.445808, 'p_SMR_multi': 6.033717e-13, 'Disease': 'AD', 'b_SMR': 0.0484187, 'p_HEIDI': 0.0001981533}]
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SMR Significance, Effect