uuid stringlengths 4 8 | template_uuid stringclasses 40
values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 133 622 | execution_results stringlengths 2 1.14M | query_type stringclasses 2
values | sql_category stringclasses 26
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Q6.1012 | Q6 | What genes does Meloxicam target when it's used to treat juvenile idiopathic arthritis? | When used to treat juvenile idiopathic arthritis, the drug Meloxicam targets the gene PTGS2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%meloxicam%" OR LOWER(tradeNames_list) LIKE "%melo... | [{'UUID': 'DrugTargetsIndication121923_text_842374', 'drugName': 'Meloxicam', 'tradeNames_list': "['Anjeso', 'Meloxicam', 'Mobic', 'Qmiiz odt', 'Vivlodex']", 'syns_list': "['Acticam', 'Contacera', 'Coxicam', 'Emdocam', 'Flexicam', 'Inflacam', 'LoxicomMelfax', 'Melosus', 'Melovem', 'Meloxicam', 'Meloxidolor', 'Meloxidyl... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1724 | Q6 | What genes does Phenylephrine Hydrochloride target when it's used to treat cataract? | Phenylephrine Hydrochloride has not been approved by the FDA as a treatment for cataract, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are ADRA1A, ADRA1D, and ADRA1B. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%phenylephrine hydrochloride%" OR LOWER(tradeNames... | [{'UUID': 'DrugTargetsIndication121923_text_416695', 'drugName': 'Phenylephrine Hydrochloride', 'tradeNames_list': "['Afrin 4 hour nasal spray', 'Biomydrin', 'Biorphen', 'Fenilfar', 'FenoxMydfrin', 'Nazex', 'Neo-synephrine', 'Neosynephrine', 'NostrilNurofen sinus pain relief', 'Phenylephrine hydrochloride', 'PrefrinVaz... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.266 | Q6 | What genes does Olodaterol target when it's used to treat asthma? | Olodaterol has not been approved by the FDA as a treatment for asthma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is ADRB2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%olodaterol%" OR LOWER(tradeNames_list) LIKE "%olo... | [{'UUID': 'DrugTargetsIndication121923_text_937155', 'drugName': 'Olodaterol', 'tradeNames_list': "['Striverdi respimat']", 'syns_list': "['BI 1744', 'Olodaterol']", 'target': 'ENSG00000169252', 'approvedSymbol': 'ADRB2', 'approvedName': 'adrenoceptor beta 2', 'mesh_heading': 'Asthma', 'efo_term': 'asthma', 'yearOfFirs... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1570 | Q6 | What genes does Aspirin target when it's used to treat thrombotic disease? | When used to treat thrombotic disease, the drug Aspirin targets the genes PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%aspirin%" OR LOWER(tradeNames_list) LIKE "%aspiri... | [{'UUID': 'DrugTargetsIndication121923_text_834441', 'drugName': 'Aspirin', 'tradeNames_list': "['8-hour bayer', 'Acetosalic Acid', 'Acetylsalic acidAcetylsalicylic Acid', 'Alka rapid', 'Anadin all night', 'Angettes 75Aspirin', 'Aspro clr', 'Bayer extra strength aspirin for migraine painDanamep', 'Disprin cv', 'Disprin... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1832 | Q6 | What genes does Aspirin target when it's used to treat atrial fibrillation? | Aspirin has not been approved by the FDA as a treatment for atrial fibrillation, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%aspirin%" OR LOWER(tradeNames_list) LIKE "%aspiri... | [{'UUID': 'DrugTargetsIndication121923_text_834352', 'drugName': 'Aspirin', 'tradeNames_list': "['8-hour bayer', 'Acetosalic Acid', 'Acetylsalic acidAcetylsalicylic Acid', 'Alka rapid', 'Anadin all night', 'Angettes 75Aspirin', 'Aspro clr', 'Bayer extra strength aspirin for migraine painDanamep', 'Disprin cv', 'Disprin... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.449 | Q6 | What genes does Mesalamine target when it's used to treat ulcerative colitis? | When used to treat ulcerative colitis, the drug Mesalamine targets the genes PTGS2, PTGS1, PPARG, and ALOX5. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%mesalamine%" OR LOWER(tradeNames_list) LIKE "%mes... | [{'UUID': 'DrugTargetsIndication121923_text_842714', 'drugName': 'Mesalamine', 'tradeNames_list': "['Apriso', 'Asacol', 'Asacol hd', 'Canasa', 'Coltec ec', 'Delzicol', 'IpocolLialda', 'Mesalamine', 'Mesren mr', 'Mezavant xl', 'Octasa', 'PentasaPentasa sr', 'Rowasa', 'Salofalk', 'Sfrowasa']", 'syns_list': "['Benzoic aci... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1011 | Q6 | What genes does Hydrocortisone target when it's used to treat pneumonia? | When used to treat pneumonia, the drug Hydrocortisone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%hydrocortisone%" OR LOWER(tradeNames_list) LIKE "... | [{'UUID': 'DrugTargetsIndication121923_text_218887', 'drugName': 'Prednisone', 'tradeNames_list': "['Cortan', 'Cortancyl', 'Decortisyl', 'Delta-dome', 'Deltasone', 'FernisoneLiquid pred', 'Lodotra', 'Meticorten', 'Orasone', 'Paracort', 'Prednicen-mPrednisone', 'Prednisone intensol', 'Rayos', 'Servisone', 'Sterapred']",... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1086 | Q6 | What genes does Epinephrine target when it's used to treat allergic disease? | When used to treat allergic disease, the drug Epinephrine targets the genes ADRA1A, ADRB2, ADRB1, ADRB3, ADRA1D, ADRA1B, ADRA2A, ADRA2C, and ADRA2B. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%epinephrine%" OR LOWER(tradeNames_list) LIKE "%ep... | [{'UUID': 'DrugTargetsIndication121923_text_361102', 'drugName': 'Epinephrine', 'tradeNames_list': "['Adren co', 'Adrenaclick', 'Adrenalin', 'Ana-Kit', 'Ana-guard', 'AnapenAnaphylactic shock drug kit', 'Asma-vydrin', 'Asthmahaler', 'Auvi-qBronkaid mist', 'Brovon', 'Emerade', 'Epi e z pen jr', 'EpinephrineEpinephrine (c... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.844 | Q6 | What genes does Dexamethasone target when it's used to treat osteoarthritis? | When used to treat osteoarthritis, the drug Dexamethasone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexamethasone%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_230369', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1792 | Q6 | What genes does Aspirin target when it's used to treat common cold? | When used to treat common cold, the drug Aspirin targets the genes PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%aspirin%" OR LOWER(tradeNames_list) LIKE "%aspiri... | [{'UUID': 'DrugTargetsIndication121923_text_833967', 'drugName': 'Aspirin', 'tradeNames_list': "['8-hour bayer', 'Acetosalic Acid', 'Acetylsalic acidAcetylsalicylic Acid', 'Alka rapid', 'Anadin all night', 'Angettes 75Aspirin', 'Aspro clr', 'Bayer extra strength aspirin for migraine painDanamep', 'Disprin cv', 'Disprin... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.308 | Q6 | What genes does Prednisone target when it's used to treat berylliosis? | When used to treat berylliosis, the drug Prednisone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%prednisone%" OR LOWER(tradeNames_list) LIKE "%pre... | [{'UUID': 'DrugTargetsIndication121923_text_218693', 'drugName': 'Prednisone', 'tradeNames_list': "['Cortan', 'Cortancyl', 'Decortisyl', 'Delta-dome', 'Deltasone', 'FernisoneLiquid pred', 'Lodotra', 'Meticorten', 'Orasone', 'Paracort', 'Prednicen-mPrednisone', 'Prednisone intensol', 'Rayos', 'Servisone', 'Sterapred']",... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1380 | Q6 | What genes does Topiramate target when it's used to treat hypertension? | Topiramate has not been approved by the FDA as a treatment for hypertension, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, SCN10A, CA2, CA4, GABRA1, GABRB2, GABRG2, GABRB3, GABRA4, GABRG3, GABR... | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%topiramate%" OR LOWER(tradeNames_list) LIKE "%top... | [{'UUID': 'DrugTargetsIndication121923_text_457440', 'drugName': 'Topiramate', 'tradeNames_list': "['Epitomax', 'Eprontia', 'Qudexy xr', 'Topamax', 'Topamax sprinkleTopiramate', 'Trokendi xr']", 'syns_list': "['(-)-topiramate', 'Epitoma', 'Eprontia', 'MCN-4853', 'Qudexy', 'RWJ-17021RWJ-17021-000', 'Sincronil', 'Topamac... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1558 | Q6 | What genes does Octreotide Acetate target when it's used to treat carcinoid tumor? | When used to treat carcinoid tumor, the drug Octreotide Acetate targets the genes SSTR5, SSTR2, SSTR3, SSTR1, and SSTR4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%octreotide acetate%" OR LOWER(tradeNames_list) LI... | [{'UUID': 'DrugTargetsIndication121923_text_1042123', 'drugName': 'Octreotide Acetate', 'tradeNames_list': "['Bynfezia pen', 'Mycapssa', 'Octreotide acetateOctreotide acetate (preservative free)Octreotide acetate preservative free', 'Sandostatin', 'Sandostatin lar']", 'syns_list': "['Octreolin', 'Octreotide (as acetate... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.317 | Q6 | What genes does Beclomethasone Dipropionate target when it's used to treat bronchopulmonary dysplasia? | Beclomethasone Dipropionate has not been approved by the FDA as a treatment for bronchopulmonary dysplasia, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%beclomethasone dipropionate%" OR LOWER(tradeNames... | [{'UUID': 'DrugTargetsIndication121923_text_221040', 'drugName': 'Beclomethasone Dipropionate', 'tradeNames_list': "['Aerobec 100', 'Aerobec 50', 'Aerobec fte 250', 'Asmabec clickhalerAsmabec spacehaler', 'Beclazone 100', 'Beclazone 100 e-breatheBeclazone 200', 'Beclazone 250', 'Beclazone 250 e-breathe', 'Beclazone 50B... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.152 | Q6 | What genes does Golodirsen target when it's used to treat muscular dystrophy? | When used to treat muscular dystrophy, the drug Golodirsen targets the gene DMD. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%golodirsen%" OR LOWER(tradeNames_list) LIKE "%gol... | [{'UUID': 'DrugTargetsIndication121923_text_1100513', 'drugName': 'Golodirsen', 'tradeNames_list': "['Vyondys 53']", 'syns_list': "['Golodirsen', 'NG-12-0163', 'SRP-4053']", 'target': 'ENSG00000198947', 'approvedSymbol': 'DMD', 'approvedName': 'dystrophin', 'mesh_heading': 'Muscular Dystrophies', 'efo_term': 'muscular ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1158 | Q6 | What genes does Clobazam target when it's used to treat anxiety? | When used to treat anxiety, the drug Clobazam targets the genes GABRA1, GABRB2, GABRG2, GABRB3, GABRA4, GABRG3, GABRQ, GABRA3, GABRP, GABRD, GABRG1, GABRB1, GABRE, GABRA2, GABRA5, and GABRA6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%clobazam%" OR LOWER(tradeNames_list) LIKE "%cloba... | [{'UUID': 'DrugTargetsIndication121923_text_947359', 'drugName': 'Clobazam', 'tradeNames_list': "['Frisium', 'Onfi', 'Perizam', 'Sympazan', 'Tapclob', 'Urbanyl']", 'syns_list': "['Clobazam', 'Colbazam', 'H 4723', 'H-4723', 'HR 376', 'HR-376', 'LM 2717LM-2717', 'Mystan', 'NSC-336279', 'Urbadan']", 'target': 'ENSG0000002... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1223 | Q6 | What genes does Risperidone target when it's used to treat psychosis? | When used to treat psychosis, the drug Risperidone targets the genes HTR2C, DRD2, and HTR2A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%risperidone%" OR LOWER(tradeNames_list) LIKE "%ri... | [{'UUID': 'DrugTargetsIndication121923_text_149655', 'drugName': 'Risperidone', 'tradeNames_list': "['Perseris kit', 'Risperdal', 'Risperdal Consta Long Acting', 'Risperdal MRisperdal M-Tab', 'Risperdal consta', 'Risperdal quicklet', 'Risperidone']", 'syns_list': "['LY-03004', 'LY03004', 'N05AX08', 'NSC-759895', 'Perse... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.580 | Q6 | What genes does Bortezomib target when it's used to treat lung cancer? | Bortezomib has not been approved by the FDA as a treatment for lung cancer, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are PSMD1, PSMB2, PSMB1, PSMB5, PSMB8, PSMB9, PSMB6, PSMD14, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMA7, PSMA8, PSMB10, PSMB11, PSMB3,... | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%bortezomib%" OR LOWER(tradeNames_list) LIKE "%bor... | [{'UUID': 'DrugTargetsIndication121923_text_342322', 'drugName': 'Bortezomib', 'tradeNames_list': "['Velcade']", 'syns_list': "['Bortezomib', 'Bortezomib accord', 'Bortezomib hydrate', 'LDP-341NSC-681239', 'PS-341', 'Velcade']", 'target': 'ENSG00000126067', 'approvedSymbol': 'PSMB2', 'approvedName': 'proteasome 20S sub... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.51 | Q6 | What genes does Sirolimus target when it's used to treat Beta-thalassemia? | Sirolimus has not been approved by the FDA as a treatment for Beta-thalassemia, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is FKBP1A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%sirolimus%" OR LOWER(tradeNames_list) LIKE "%siro... | [{'UUID': 'DrugTargetsIndication121923_text_1084519', 'drugName': 'Sirolimus', 'tradeNames_list': "['Fyarro', 'Hyftor', 'Rapamune', 'Sirolimus']", 'syns_list': "['AY-22989', 'Fyarro', 'Hyftor', 'L04AA10', 'NSC-226080', 'Npc-12g', 'RapalimusRapamycin', 'SM-88 COMPONENT SIROLIMUS', 'Sirolimus', 'WY-090217']", 'target': '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1553 | Q6 | What genes does Nitroglycerin target when it's used to treat congestive heart failure? | When used to treat congestive heart failure, the drug Nitroglycerin targets the genes GUCY1B1, GUCY1B2, GUCY1A2, and GUCY1A1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%nitroglycerin%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_972645', 'drugName': 'Nitroglycerin', 'tradeNames_list': "['Coro-nitro', 'Deponit 10', 'Deponit 5', 'Glytrin', 'Gonitro', 'Lenitral 7.5Minitran', 'Minitran 10', 'Minitran 15', 'Minitran 5', 'NatiroseNitriderm tts', 'Nitro iv', 'Nitro-bid', 'Nitro-dur', 'Nitro-mack retNitrocin... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.733 | Q6 | What genes does Solifenacin Succinate target when it's used to treat overactive bladder? | When used to treat overactive bladder, the drug Solifenacin Succinate targets the genes CHRM3 and CHRM2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%solifenacin succinate%" OR LOWER(tradeNames_list)... | [{'UUID': 'DrugTargetsIndication121923_text_857280', 'drugName': 'Solifenacin Succinate', 'tradeNames_list': "['Solifenacin succinate', 'Vesicare', 'Vesicare ls']", 'syns_list': "['Solifenacin succinate', 'YM-67905', 'YM-905', 'YM67905', 'YM905']", 'target': 'ENSG00000133019', 'approvedSymbol': 'CHRM3', 'approvedName':... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.840 | Q6 | What genes does Bempedoic Acid target when it's used to treat cardiovascular disease? | When used to treat cardiovascular disease, the drug Bempedoic Acid targets the gene ACLY. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%bempedoic acid%" OR LOWER(tradeNames_list) LIKE "... | [{'UUID': 'DrugTargetsIndication121923_text_1191840', 'drugName': 'Bempedoic Acid', 'tradeNames_list': "['Nexletol']", 'syns_list': "['Bempedoic acid', 'ESP-55016', 'ETC-1002', 'ETC1002']", 'target': 'ENSG00000131473', 'approvedSymbol': 'ACLY', 'approvedName': 'ATP citrate lyase', 'mesh_heading': 'Cardiovascular Diseas... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1392 | Q6 | What genes does Abemaciclib target when it's used to treat malignant rhabdoid tumour? | Abemaciclib has not been approved by the FDA as a treatment for malignant rhabdoid tumour, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are CDK4 and CDK6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%abemaciclib%" OR LOWER(tradeNames_list) LIKE "%ab... | [{'UUID': 'DrugTargetsIndication121923_text_849316', 'drugName': 'Abemaciclib', 'tradeNames_list': "['Verzenio', 'Verzenios']", 'syns_list': "['Abemaciclib', 'LY-2835219', 'LY2835219', 'Ly-2835219']", 'target': 'ENSG00000135446', 'approvedSymbol': 'CDK4', 'approvedName': 'cyclin dependent kinase 4', 'mesh_heading': 'Rh... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1125 | Q6 | What genes does Sorafenib target when it's used to treat acute monocytic leukemia? | Sorafenib has not been approved by the FDA as a treatment for acute monocytic leukemia, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are KDR, BRAF, FLT1, FLT3, KIT, FLT4, PDGFRB, RAF1, and RET. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%sorafenib%" OR LOWER(tradeNames_list) LIKE "%sora... | [{'UUID': 'DrugTargetsIndication121923_text_686296', 'drugName': 'Sorafenib', 'tradeNames_list': "['Nexavar']", 'syns_list': "['BAY 43-9006', 'BAY-43-9006', 'Sorafenib']", 'target': 'ENSG00000157764', 'approvedSymbol': 'BRAF', 'approvedName': 'B-Raf proto-oncogene, serine/threonine kinase', 'mesh_heading': 'Leukemia, M... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1176 | Q6 | What genes does Buprenorphine target when it's used to treat sickle cell anemia? | Buprenorphine has not been approved by the FDA as a treatment for sickle cell anemia, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are OPRM1 and OPRK1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%buprenorphine%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_764179', 'drugName': 'Buprenorphine', 'tradeNames_list': "['Bupeaze', 'Buplast', 'Butec', 'Butrans', 'Hapoctasin', 'Panitaz', 'PrenotrixReletrans', 'Sevodyne', 'Sublocade', 'Temgesic', 'Tephine', 'Transtec']", 'syns_list': "['ALKS-5461 COMPONENT BUPRENORPHINE', 'Brixadi', 'Bu... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.476 | Q6 | What genes does Dexamethasone target when it's used to treat seborrheic dermatitis? | When used to treat seborrheic dermatitis, the drug Dexamethasone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexamethasone%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_227788', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.980 | Q6 | What genes does Naproxen Sodium target when it's used to treat Dysmenorrhea? | When used to treat Dysmenorrhea, the drug Naproxen Sodium targets the genes PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%naproxen sodium%" OR LOWER(tradeNames_list) LIKE ... | [{'UUID': 'DrugTargetsIndication121923_text_838128', 'drugName': 'Naproxen Sodium', 'tradeNames_list': "['Aleve', 'Anaprox', 'Anaprox ds', 'Naprelan', 'Naproxen sodium', 'Synflex']", 'syns_list': "['BAY-117031', 'BAY117031', 'BAYH6689', 'Naproxen sodiumNaproxen sodium anhydrous', 'Naproxen sodium salt', 'RS-3650']", 't... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.660 | Q6 | What genes does Halobetasol Propionate target when it's used to treat skin disease? | When used to treat skin disease, the drug Halobetasol Propionate targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%halobetasol propionate%" OR LOWER(tradeNames_list... | [{'UUID': 'DrugTargetsIndication121923_text_240740', 'drugName': 'Halobetasol Propionate', 'tradeNames_list': "['Bryhali', 'Halobetasol propionate', 'Lexette', 'Ultravate']", 'syns_list': "['21-chloro diflorasone', 'BMY-30056', 'CGP-14,458', 'CGP-14458Halobetasol', 'Halobetasol propionate', 'IDP-122', 'Jemdel', 'Ulobet... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.405 | Q6 | What genes does Amlodipine Benzoate target when it's used to treat stroke? | When used to treat stroke, the drug Amlodipine Benzoate targets the genes CACNA1C, CACNA1S, CACNA1D, and CACNA1F. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%amlodipine benzoate%" OR LOWER(tradeNames_list) L... | [{'UUID': 'DrugTargetsIndication121923_text_1044028', 'drugName': 'Amlodipine Benzoate', 'tradeNames_list': "['Katerzia']", 'syns_list': "['Amlodipine benzoate']", 'target': 'ENSG00000151067', 'approvedSymbol': 'CACNA1C', 'approvedName': 'calcium voltage-gated channel subunit alpha1 C', 'mesh_heading': 'Stroke', 'efo_t... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.517 | Q6 | What genes does Tenapanor Hydrochloride target when it's used to treat irritable bowel syndrome? | When used to treat irritable bowel syndrome, the drug Tenapanor Hydrochloride targets the gene SLC9A3. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%tenapanor hydrochloride%" OR LOWER(tradeNames_lis... | [{'UUID': 'DrugTargetsIndication121923_text_1094308', 'drugName': 'Tenapanor Hydrochloride', 'tradeNames_list': "['Ibsrela']", 'syns_list': "['AZD-1722 HYDROCHLORIDE', 'AZD1722', 'AZD1722 hydrochloride', 'RDX-5791RDX5791', 'Tenapanor dihydrochloride', 'Tenapanor hydrochloride']", 'target': 'ENSG00000066230', 'approvedS... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.324 | Q6 | What genes does Eltrombopag Olamine target when it's used to treat autoimmune thrombocytopenic purpura? | When used to treat autoimmune thrombocytopenic purpura, the drug Eltrombopag Olamine targets the gene MPL. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%eltrombopag olamine%" OR LOWER(tradeNames_list) L... | [{'UUID': 'DrugTargetsIndication121923_text_1055975', 'drugName': 'Eltrombopag Olamine', 'tradeNames_list': "['Promacta', 'Promacta kit']", 'syns_list': "['Eltrombopag (as olamine)', 'Eltrombopag compd with 2-aminoethanol (1:2)Eltrombopag olamine', 'SB-497115-GR']", 'target': 'ENSG00000117400', 'approvedSymbol': 'MPL',... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.20 | Q6 | What genes does Ribavirin target when it's used to treat infection? | Ribavirin has not been approved by the FDA as a treatment for infection, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is IMPDH1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ribavirin%" OR LOWER(tradeNames_list) LIKE "%riba... | [{'UUID': 'DrugTargetsIndication121923_text_937591', 'drugName': 'Ribavirin', 'tradeNames_list': "['Copegus', 'Rebetol', 'Ribapak', 'Ribasphere', 'Ribavarin', 'RibavirinRibofluranosyl Carboxamide', 'Tribavirin', 'Viramid', 'Virazid', 'Virazole']", 'syns_list': "['Cotronak', 'NSC-163039', 'Ribavirin', 'Ribavirin biopart... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.691 | Q6 | What genes does Bivalirudin target when it's used to treat intermediate coronary syndrome? | When used to treat intermediate coronary syndrome, the drug Bivalirudin targets the gene F2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%bivalirudin%" OR LOWER(tradeNames_list) LIKE "%bi... | [{'UUID': 'DrugTargetsIndication121923_text_1092329', 'drugName': 'Bivalirudin', 'tradeNames_list': "['Angiomax', 'Angiomax rtu', 'BivalirudinBivalirudin in 0.9% sodium chloride']", 'syns_list': "['BG-8967', 'BG8967', 'Bivalirudin']", 'target': 'ENSG00000180210', 'approvedSymbol': 'F2', 'approvedName': 'coagulation fac... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.36 | Q6 | What genes does Ketorolac Tromethamine target when it's used to treat pain? | When used to treat pain, the drug Ketorolac Tromethamine targets the genes PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ketorolac tromethamine%" OR LOWER(tradeNames_list... | [{'UUID': 'DrugTargetsIndication121923_text_842137', 'drugName': 'Ketorolac Tromethamine', 'tradeNames_list': "['Acular', 'Acular ls', 'Acular preservative free', 'AcuvailKetorolac tromethamine', 'Sprix', 'Toradol']", 'syns_list': "['Dolac', 'Ketorolac trometamol', 'Ketorolac tromethamine', 'LixidolNSC-758637', 'Tarasy... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.910 | Q6 | What genes does Belzutifan target when it's used to treat pancreatic neuroendocrine tumor? | When used to treat pancreatic neuroendocrine tumor, the drug Belzutifan targets the gene EPAS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%belzutifan%" OR LOWER(tradeNames_list) LIKE "%bel... | [{'UUID': 'DrugTargetsIndication121923_text_1192113', 'drugName': 'Belzutifan', 'tradeNames_list': "['Welireg']", 'syns_list': "['Belzutifan', 'MK-6482', 'MK6482', 'Mk-6482', 'PT-2977', 'PT2977', 'Pt 2977Pt2977']", 'target': 'ENSG00000116016', 'approvedSymbol': 'EPAS1', 'approvedName': 'endothelial PAS domain protein 1... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.834 | Q6 | What genes does Amlodipine Besylate target when it's used to treat stroke? | When used to treat stroke, the drug Amlodipine Besylate targets the genes CACNA1C, CACNA1S, CACNA1D, and CACNA1F. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%amlodipine besylate%" OR LOWER(tradeNames_list) L... | [{'UUID': 'DrugTargetsIndication121923_text_1043736', 'drugName': 'Amlodipine Besylate', 'tradeNames_list': "['Amlodipine besylate', 'Norliqva', 'Norvasc']", 'syns_list': "['Amlodipine (as besilate)', 'Amlodipine benzenesulfonateAmlodipine besilate', 'Amlodipine besylate', 'Amlor', 'AntacalLodipressin', 'Monopina', 'NS... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1798 | Q6 | What genes does Prednisone target when it's used to treat choroiditis? | When used to treat choroiditis, the drug Prednisone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%prednisone%" OR LOWER(tradeNames_list) LIKE "%pre... | [{'UUID': 'DrugTargetsIndication121923_text_218717', 'drugName': 'Prednisone', 'tradeNames_list': "['Cortan', 'Cortancyl', 'Decortisyl', 'Delta-dome', 'Deltasone', 'FernisoneLiquid pred', 'Lodotra', 'Meticorten', 'Orasone', 'Paracort', 'Prednicen-mPrednisone', 'Prednisone intensol', 'Rayos', 'Servisone', 'Sterapred']",... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.413 | Q6 | What genes does Plerixafor target when it's used to treat Beta-thalassemia? | Plerixafor has not been approved by the FDA as a treatment for Beta-thalassemia, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is CXCR4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%plerixafor%" OR LOWER(tradeNames_list) LIKE "%ple... | [{'UUID': 'DrugTargetsIndication121923_text_1103190', 'drugName': 'Plerixafor', 'tradeNames_list': "['Mozobil']", 'syns_list': "['AMD 3100', 'AMD3100', 'JM 3100', 'Plerixafor', 'Plerixafor hydrochloridePlerixafor octahydrochloride', 'SID 791']", 'target': 'ENSG00000121966', 'approvedSymbol': 'CXCR4', 'approvedName': 'C... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.928 | Q6 | What genes does Ibuprofen target when it's used to treat Fever? | When used to treat Fever, the drug Ibuprofen targets the genes PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ibuprofen%" OR LOWER(tradeNames_list) LIKE "%ibup... | [{'UUID': 'DrugTargetsIndication121923_text_840155', 'drugName': 'Ibuprofen', 'tradeNames_list': '[\'Aches-n-pain\', \'Advil\', \'Advil liqui-gels\', \'Advil migraine liqui-gelsAnadin joint pain\', \'Anadin liquifast\', \'Anadin period pain reliefAnadin ultra\', \'Apsifen\', \'Apsifen-f\', \'Arthrofen 200\', \'Arthrofe... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.543 | Q6 | What genes does Bimatoprost target when it's used to treat glaucoma? | When used to treat glaucoma, the drug Bimatoprost targets the gene PTGFR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%bimatoprost%" OR LOWER(tradeNames_list) LIKE "%bi... | [{'UUID': 'DrugTargetsIndication121923_text_1149148', 'drugName': 'Bimatoprost', 'tradeNames_list': "['Bimatoprost', 'Durysta', 'Latisse', 'Lumigan']", 'syns_list': "['AGN 192024', 'AGN-192024', 'Bimatoprost', 'Prostamide']", 'target': 'ENSG00000122420', 'approvedSymbol': 'PTGFR', 'approvedName': 'prostaglandin F recep... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.765 | Q6 | What genes does Dronabinol target when it's used to treat Cognitive impairment? | Dronabinol has not been approved by the FDA as a treatment for Cognitive impairment, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is CNR1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dronabinol%" OR LOWER(tradeNames_list) LIKE "%dro... | [{'UUID': 'DrugTargetsIndication121923_text_1073258', 'drugName': 'Dronabinol', 'tradeNames_list': "['Dronabinol', 'Marinol', 'Syndros']", 'syns_list': "['.delta.-9-tetrahydrocannabinol', '.delta.1-thc.delta.9-tetrahydrocannabinol', '.delta.9-thc', 'ABBOTT 40566ABBOTT-40566', 'Delta-9-tetrahydrocannabinol', 'Delta-9-th... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1905 | Q6 | What genes does Sitagliptin target when it's used to treat non-alcoholic fatty liver disease? | Sitagliptin has not been approved by the FDA as a treatment for non-alcoholic fatty liver disease, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is DPP4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%sitagliptin%" OR LOWER(tradeNames_list) LIKE "%si... | [{'UUID': 'DrugTargetsIndication121923_text_933420', 'drugName': 'Sitagliptin', 'tradeNames_list': "['Januvia']", 'syns_list': "['LEZ-763', 'LEZ763', 'MK-0431', 'Sitagliptin']", 'target': 'ENSG00000197635', 'approvedSymbol': 'DPP4', 'approvedName': 'dipeptidyl peptidase 4', 'mesh_heading': 'Non-alcoholic Fatty Liver Di... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1071 | Q6 | What genes does Dexamethasone target when it's used to treat cancer? | When used to treat cancer, the drug Dexamethasone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexamethasone%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_228601', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1209 | Q6 | What genes does Trametinib Dimethyl Sulfoxide target when it's used to treat metastatic melanoma? | When used to treat metastatic melanoma, the drug Trametinib Dimethyl Sulfoxide targets the genes MAP2K2 and MAP2K1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%trametinib dimethyl sulfoxide%" OR LOWER(tradeNam... | [{'UUID': 'DrugTargetsIndication121923_text_927765', 'drugName': 'Trametinib Dimethyl Sulfoxide', 'tradeNames_list': "['Mekinist']", 'syns_list': "['GSK-1120212B', 'GSK1120212B', 'Trametinib dimethyl sulfoxide']", 'target': 'ENSG00000126934', 'approvedSymbol': 'MAP2K2', 'approvedName': 'mitogen-activated protein kinase... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.248 | Q6 | What genes does Regorafenib target when it's used to treat colon adenocarcinoma? | Regorafenib has not been approved by the FDA as a treatment for colon adenocarcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are KDR, FGFR1, FGFR2, ABL1, BRAF, TEK, FLT1, KIT, FLT4, PDGFRB, PDGFRA, RAF1, EPHA2, FRK, NTRK1, RET, DDR2, and MAPK11. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%regorafenib%" OR LOWER(tradeNames_list) LIKE "%re... | [{'UUID': 'DrugTargetsIndication121923_text_664233', 'drugName': 'Regorafenib', 'tradeNames_list': "['Stivarga']", 'syns_list': "['BAY 73-4506', 'BAY 73-4506 monohydrate', 'BAY-73-4506', 'BAY-734506Regorafenib', 'Regorafenib anhydrous', 'Regorafenib hydrateRegorafenib monohydrate']", 'target': 'ENSG00000077782', 'appro... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1431 | Q6 | What genes does Baclofen target when it's used to treat multiple sclerosis? | When used to treat multiple sclerosis, the drug Baclofen targets the genes GABBR1 and GABBR2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%baclofen%" OR LOWER(tradeNames_list) LIKE "%baclo... | [{'UUID': 'DrugTargetsIndication121923_text_1193248', 'drugName': 'Baclofen', 'tradeNames_list': "['Baclofen', 'Baclospas-10', 'Fleqsuvy', 'Gablofen', 'Kemstro', 'LioresalLioresal intrath', 'Lyflex', 'Lyvispah', 'Ozobax']", 'syns_list': "['(rs)-baclofen', 'BA-34,647', 'BA-34647', 'Baclofen', 'Fleqsuvy', 'LyvispahNSC-75... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1137 | Q6 | What genes does Crofelemer target when it's used to treat Diarrhea? | When used to treat Diarrhea, the drug Crofelemer targets the genes CFTR and ANO1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%crofelemer%" OR LOWER(tradeNames_list) LIKE "%cro... | [{'UUID': 'DrugTargetsIndication121923_text_1103274', 'drugName': 'Crofelemer', 'tradeNames_list': "['Fulyzaq', 'Mytesi', 'Provir', 'Virend']", 'syns_list': "['Crofelemer', 'NP-303', 'SP-303', 'TRN-002']", 'target': 'ENSG00000131620', 'approvedSymbol': 'ANO1', 'approvedName': 'anoctamin 1', 'mesh_heading': 'Diarrhea', ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.791 | Q6 | What genes does Indomethacin target when it's used to treat rheumatoid arthritis? | When used to treat rheumatoid arthritis, the drug Indomethacin targets the genes PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%indomethacin%" OR LOWER(tradeNames_list) LIKE "%i... | [{'UUID': 'DrugTargetsIndication121923_text_828371', 'drugName': 'Indomethacin', 'tradeNames_list': "['Artracin', 'Artracin sr', 'Berlind 75 ret', 'Flexin-25 continusFlexin-50 continus', 'Flexin-75 continus', 'Imbrilon', 'Indo-lemmonIndo-paed', 'Indocid ret', 'Indocid-r', 'Indocin', 'Indocin sr', 'IndodermIndoflex', 'I... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1744 | Q6 | What genes does Binimetinib target when it's used to treat thyroid carcinoma? | Binimetinib has not been approved by the FDA as a treatment for thyroid carcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are MAP2K2 and MAP2K1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%binimetinib%" OR LOWER(tradeNames_list) LIKE "%bi... | [{'UUID': 'DrugTargetsIndication121923_text_926773', 'drugName': 'Binimetinib', 'tradeNames_list': "['Mektovi']", 'syns_list': "['ARRY 438162', 'ARRY-162', 'ARRY-438162', 'Binimetinib', 'MEK-162', 'MEK162Mek-162', 'NVP-MEK162']", 'target': 'ENSG00000126934', 'approvedSymbol': 'MAP2K2', 'approvedName': 'mitogen-activate... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.495 | Q6 | What genes does Amisulpride target when it's used to treat post operative nausea and vomiting? | When used to treat post operative nausea and vomiting, the drug Amisulpride targets the genes HTR2C, DRD2, DRD3, HTR2A, HTR3A, HTR1A, HTR3E, HTR3B, HTR3D, HTR3C, HTR4, HTR1F, HTR2B, HTR1B, HTR1D, HTR1E, HTR7, HTR6, and HTR5A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%amisulpride%" OR LOWER(tradeNames_list) LIKE "%am... | [{'UUID': 'DrugTargetsIndication121923_text_151512', 'drugName': 'Amisulpride', 'tradeNames_list': "['Barhemsys', 'Solian', 'Solian 100', 'Solian 200', 'Solian 400', 'Solian 50']", 'syns_list': "['APD-421', 'APD421', 'Aminosultopride', 'Amisulpride', 'DAN-2163', 'DenibanNSC-760085', 'Socian', 'Sulamid']", 'target': 'EN... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.157 | Q6 | What genes does Pazopanib Hydrochloride target when it's used to treat soft tissue sarcoma? | When used to treat soft tissue sarcoma, the drug Pazopanib Hydrochloride targets the genes KDR, FGFR1, FGFR3, FLT1, KIT, FLT4, PDGFRB, PDGFRA, LCK, CSF1R, and ITK. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%pazopanib hydrochloride%" OR LOWER(tradeNames_lis... | [{'UUID': 'DrugTargetsIndication121923_text_667968', 'drugName': 'Pazopanib Hydrochloride', 'tradeNames_list': "['Votrient']", 'syns_list': "['GW-786034B', 'GW786034B', 'Pazopanib (as hydrochloride)', 'Pazopanib hclPazopanib hydrochloride', 'Pazopanib monohydrochloride']", 'target': 'ENSG00000068078', 'approvedSymbol':... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.970 | Q6 | What genes does Metformin Hydrochloride target when it's used to treat diabetes mellitus? | When used to treat diabetes mellitus, the drug Metformin Hydrochloride targets the genes MT-ND6, NDUFA10, NDUFS8, MT-ND4L, NDUFA6, MT-ND1, NDUFB6, NDUFA4, NDUFA11, NDUFB7, MT-ND2, NDUFS2, MT-ND5, NDUFA8, NDUFB5, MT-ND4, MT-ND3, NDUFAB1, NDUFA1, NDUFS4, NDUFB3, NDUFC1, NDUFA2, NDUFS5, NDUFS7, NDUFS6, NDUFB1, NDUFS3, NDU... | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%metformin hydrochloride%" OR LOWER(tradeNames_lis... | [{'UUID': 'DrugTargetsIndication121923_text_1149601', 'drugName': 'Metformin Hydrochloride', 'tradeNames_list': "['Bolamyn sr', 'Diagemet xl', 'Fortamet', 'Glucamet 500', 'Glucamet 850Glucient sr', 'Glucophage', 'Glucophage sr', 'Glucophage xr', 'GlumetzaGlyformin', 'Janumet', 'Ledermetin', 'Metabet sr', 'Metformin hyd... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.860 | Q6 | What genes does Lansoprazole target when it's used to treat cystic fibrosis? | Lansoprazole has not been approved by the FDA as a treatment for cystic fibrosis, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are ATP4A and ATP4B. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lansoprazole%" OR LOWER(tradeNames_list) LIKE "%l... | [{'UUID': 'DrugTargetsIndication121923_text_1098349', 'drugName': 'Lansoprazole', 'tradeNames_list': "['Lansoprazole', 'Opiren', 'Prevacid', 'Prevacid 24 hrPrevacid Delayed Release', 'Prevacid Solutab', 'Prevacid iv', 'Zoton']", 'syns_list': "['A-65006', 'AG-1749', 'Agopton', 'Lansoprazole', 'Lansox', 'LanzoprazoleLanz... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1325 | Q6 | What genes does Ixabepilone target when it's used to treat cancer? | When used to treat cancer, the drug Ixabepilone targets the genes TUBB4B, TUBB1, TUBA3C, TUBA4A, TUBB3, TUBA1A, TUBB4A, TUBB8, TUBB, TUBA1B, TUBA1C, TUBA3E, TUBB2A, TUBB2B, and TUBB6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ixabepilone%" OR LOWER(tradeNames_list) LIKE "%ix... | [{'UUID': 'DrugTargetsIndication121923_text_85968', 'drugName': 'Ixabepilone', 'tradeNames_list': "['Ixempra', 'Ixempra kit']", 'syns_list': "['Azaepothilone b', 'BMS 247550-01', 'BMS-247550', 'BMS-247550-01Ixabepilone', 'Ixempra', 'NSC-747973']", 'target': 'ENSG00000101162', 'approvedSymbol': 'TUBB1', 'approvedName': ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.632 | Q6 | What genes does Plerixafor target when it's used to treat chronic lymphocytic leukemia? | Plerixafor has not been approved by the FDA as a treatment for chronic lymphocytic leukemia, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is CXCR4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%plerixafor%" OR LOWER(tradeNames_list) LIKE "%ple... | [{'UUID': 'DrugTargetsIndication121923_text_1103178', 'drugName': 'Plerixafor', 'tradeNames_list': "['Mozobil']", 'syns_list': "['AMD 3100', 'AMD3100', 'JM 3100', 'Plerixafor', 'Plerixafor hydrochloridePlerixafor octahydrochloride', 'SID 791']", 'target': 'ENSG00000121966', 'approvedSymbol': 'CXCR4', 'approvedName': 'C... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.692 | Q6 | What genes does Neratinib Maleate target when it's used to treat breast carcinoma? | When used to treat breast carcinoma, the drug Neratinib Maleate targets the genes EGFR, ERBB2, and ERBB4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%neratinib maleate%" OR LOWER(tradeNames_list) LIK... | [{'UUID': 'DrugTargetsIndication121923_text_209711', 'drugName': 'Neratinib Maleate', 'tradeNames_list': "['Nerlynx']", 'syns_list': "['Neratinib maleate', 'Neratinib maleate anhydrous']", 'target': 'ENSG00000146648', 'approvedSymbol': 'EGFR', 'approvedName': 'epidermal growth factor receptor', 'mesh_heading': 'Breast ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1562 | Q6 | What genes does Aripiprazole target when it's used to treat Agitation? | When used to treat Agitation, the drug Aripiprazole targets the genes DRD2, HTR2A, and HTR1A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%aripiprazole%" OR LOWER(tradeNames_list) LIKE "%a... | [{'UUID': 'DrugTargetsIndication121923_text_159196', 'drugName': 'Aripiprazole', 'tradeNames_list': "['Abilify', 'Abilify maintena', 'Abilify maintena kit', 'Abilify mycite kitAripiprazole']", 'syns_list': "['Abilify mycite', 'Aripiprazole', 'Aripiprex', 'NSC-759266', 'OPC-14597OPC-31']", 'target': 'ENSG00000149295', '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.575 | Q6 | What genes does Epinephrine target when it's used to treat cardiovascular disease? | When used to treat cardiovascular disease, the drug Epinephrine targets the genes ADRA1A, ADRB2, ADRB1, ADRB3, ADRA1D, ADRA1B, ADRA2A, ADRA2C, and ADRA2B. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%epinephrine%" OR LOWER(tradeNames_list) LIKE "%ep... | [{'UUID': 'DrugTargetsIndication121923_text_361088', 'drugName': 'Epinephrine', 'tradeNames_list': "['Adren co', 'Adrenaclick', 'Adrenalin', 'Ana-Kit', 'Ana-guard', 'AnapenAnaphylactic shock drug kit', 'Asma-vydrin', 'Asthmahaler', 'Auvi-qBronkaid mist', 'Brovon', 'Emerade', 'Epi e z pen jr', 'EpinephrineEpinephrine (c... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1909 | Q6 | What genes does Ceritinib target when it's used to treat cancer? | When used to treat cancer, the drug Ceritinib targets the genes ALK, EML4, and NPM1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ceritinib%" OR LOWER(tradeNames_list) LIKE "%ceri... | [{'UUID': 'DrugTargetsIndication121923_text_992314', 'drugName': 'Ceritinib', 'tradeNames_list': "['Zykadia']", 'syns_list': "['Ceritinib', 'Ceritinib[mi]', 'LDK-378', 'LDK378', 'NVP-LDK-378-NXNVP-LDK378-NX']", 'target': 'ENSG00000143924', 'approvedSymbol': 'EML4', 'approvedName': 'EMAP like 4', 'mesh_heading': 'Neopla... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.18 | Q6 | What genes does Levothyroxine Sodium target when it's used to treat thyroid carcinoma? | When used to treat thyroid carcinoma, the drug Levothyroxine Sodium targets the genes THRA and THRB. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%levothyroxine sodium%" OR LOWER(tradeNames_list) ... | [{'UUID': 'DrugTargetsIndication121923_text_924814', 'drugName': 'Levothyroxine Sodium', 'tradeNames_list': "['Eltroxin', 'Ermeza', 'Euthyrox', 'Evotrox', 'L-thyroxine henning', 'Levo-tLevolet', 'Levothroid', 'Levothyroid', 'Levothyroxine sodium', 'LevoxineLevoxyl', 'Novothyrox', 'Soloxine', 'Synthroid', 'Thyquidity', ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.130 | Q6 | What genes does Lidocaine target when it's used to treat frozen shoulder? | When used to treat frozen shoulder, the drug Lidocaine targets the genes SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lidocaine%" OR LOWER(tradeNames_list) LIKE "%lido... | [{'UUID': 'DrugTargetsIndication121923_text_638369', 'drugName': 'Lidocaine', 'tradeNames_list': "['Alphacaine', 'Anestacon', 'Dentipatch', 'Lidocaine', 'LidodermLignocaine Hcl', 'Lignostab', 'Lmx 4', 'Oraqix', 'Vagisil', 'XylocaineXylodase', 'Xylotox', 'Ztlido']", 'syns_list': "['ALGRX 3268', 'ALGRX-3268', 'Anestacon'... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1361 | Q6 | What genes does Fluticasone Propionate target when it's used to treat Nasal congestion? | When used to treat Nasal congestion, the drug Fluticasone Propionate targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fluticasone propionate%" OR LOWER(tradeNames_list... | [{'UUID': 'DrugTargetsIndication121923_text_232525', 'drugName': 'Fluticasone Propionate', 'tradeNames_list': "['Aerivio spiromax', 'Airflusal forspiro', 'Armonair digihalerArmonair respiclick', 'Cutivate', 'Flixonase', 'Flixotide', 'FlonaseFlonase allergy relief', 'Flovent', 'Flovent diskus 100Flovent diskus 250', 'Fl... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1291 | Q6 | What genes does Mifepristone target when it's used to treat persian gulf syndrome? | Mifepristone has not been approved by the FDA as a treatment for persian gulf syndrome, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are NR3C1 and PGR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%mifepristone%" OR LOWER(tradeNames_list) LIKE "%m... | [{'UUID': 'DrugTargetsIndication121923_text_242444', 'drugName': 'Mifepristone', 'tradeNames_list': "['Korlym', 'Mifegyne', 'Mifeprex']", 'syns_list': "['Mifepristone', 'NSC-759862', 'RU 38486', 'RU 486', 'RU-38486', 'RU-486RU486']", 'target': 'ENSG00000113580', 'approvedSymbol': 'NR3C1', 'approvedName': 'nuclear recep... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1969 | Q6 | What genes does Cangrelor Tetrasodium target when it's used to treat myocardial infarction? | When used to treat myocardial infarction, the drug Cangrelor Tetrasodium targets the gene P2RY12. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%cangrelor tetrasodium%" OR LOWER(tradeNames_list)... | [{'UUID': 'DrugTargetsIndication121923_text_921003', 'drugName': 'Cangrelor Tetrasodium', 'tradeNames_list': "['Kengreal']", 'syns_list': "['AR-C69931MX', 'Cangrelor', 'Cangrelor tetrasodiumCangrelor tetrasodium salt', 'Kengrexal']", 'target': 'ENSG00000169313', 'approvedSymbol': 'P2RY12', 'approvedName': 'purinergic r... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.935 | Q6 | What genes does Semaglutide target when it's used to treat diabetes mellitus? | When used to treat diabetes mellitus, the drug Semaglutide targets the gene GLP1R. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%semaglutide%" OR LOWER(tradeNames_list) LIKE "%se... | [{'UUID': 'DrugTargetsIndication121923_text_1052364', 'drugName': 'Semaglutide', 'tradeNames_list': "['Ozempic', 'Rybelsus', 'Wegovy']", 'syns_list': "['NN-9535', 'NN9535', 'NNC 0113-0217', 'NNC-0113-0217', 'Nn9535', 'Semaglutide']", 'target': 'ENSG00000112164', 'approvedSymbol': 'GLP1R', 'approvedName': 'glucagon like... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.989 | Q6 | What genes does Oxymetazoline Hydrochloride target when it's used to treat common cold? | When used to treat common cold, the drug Oxymetazoline Hydrochloride targets the genes ADRA1A, ADRA1D, ADRA1B, ADRA2A, ADRA2C, and ADRA2B. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%oxymetazoline hydrochloride%" OR LOWER(tradeNames... | [{'UUID': 'DrugTargetsIndication121923_text_417242', 'drugName': 'Oxymetazoline Hydrochloride', 'tradeNames_list': "['Afrazine', 'Ocuclear', 'Rhofade', 'Upneeq', 'Visine', 'Visine l.r.']", 'syns_list': "['Agn-199201', 'NSC-757254', 'Oximetazoline hydrochlorideOxymetazoline hcl', 'Oxymetazoline hydrochloride', 'SCH 9384... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1965 | Q6 | What genes does Oxycodone Hydrochloride target when it's used to treat Chronic pain? | When used to treat Chronic pain, the drug Oxycodone Hydrochloride targets the gene OPRM1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%oxycodone hydrochloride%" OR LOWER(tradeNames_lis... | [{'UUID': 'DrugTargetsIndication121923_text_766833', 'drugName': 'Oxycodone Hydrochloride', 'tradeNames_list': "['Abtard', 'Candox', 'Carexil', 'Dolocodon pr', 'Leveraxo', 'Longtec', 'LynlorOxaydo', 'Oxecta', 'Oxeltra', 'Oxycodone hydrochloride', 'OxycontinOxylan', 'Oxynorm', 'Reltebon', 'Roxicodone', 'Roxybond', 'Shor... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.193 | Q6 | What genes does Lidocaine Hydrochloride target when it's used to treat pain? | When used to treat pain, the drug Lidocaine Hydrochloride targets the genes SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lidocaine hydrochloride%" OR LOWER(tradeNames_lis... | [{'UUID': 'DrugTargetsIndication121923_text_637007', 'drugName': 'Lidocaine Hydrochloride', 'tradeNames_list': "['Akten', 'Alphacaine hydrochloride', 'Anestacon', 'Anodesyn', 'BismodyneBradosol plus', 'Calgel', 'Co-phenylcaine fte', 'Denela', 'DequasprayEmla', 'Germoloids', 'Germoloids complete', 'Glydo', 'Hemocane', '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1149 | Q6 | What genes does Avanafil target when it's used to treat erectile dysfunction? | When used to treat erectile dysfunction, the drug Avanafil targets the gene PDE5A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%avanafil%" OR LOWER(tradeNames_list) LIKE "%avana... | [{'UUID': 'DrugTargetsIndication121923_text_1094069', 'drugName': 'Avanafil', 'tradeNames_list': "['Spedra', 'Stendra']", 'syns_list': "['Avanafil', 'TA-1790']", 'target': 'ENSG00000138735', 'approvedSymbol': 'PDE5A', 'approvedName': 'phosphodiesterase 5A', 'mesh_heading': 'Erectile Dysfunction', 'efo_term': 'erectile ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1001 | Q6 | What genes does Ondansetron target when it's used to treat Chemotherapy-induced nausea and vomiting? | When used to treat Chemotherapy-induced nausea and vomiting, the drug Ondansetron targets the gene HTR3A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ondansetron%" OR LOWER(tradeNames_list) LIKE "%on... | [{'UUID': 'DrugTargetsIndication121923_text_205942', 'drugName': 'Ondansetron', 'tradeNames_list': "['Ondansetron', 'Zofran', 'Zofran odt', 'Zuplenz']", 'syns_list': "['A04AA01', 'Desmethylondansetron', 'EUR-1025', 'GR-38032', 'GR-38032FNSC-757870', 'Ondansetron', 'Zofran']", 'target': 'ENSG00000166736', 'approvedSymbo... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1956 | Q6 | What genes does Edoxaban Tosylate target when it's used to treat deep vein thrombosis? | When used to treat deep vein thrombosis, the drug Edoxaban Tosylate targets the gene F10. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%edoxaban tosylate%" OR LOWER(tradeNames_list) LIK... | [{'UUID': 'DrugTargetsIndication121923_text_710336', 'drugName': 'Edoxaban Tosylate', 'tradeNames_list': "['Savaysa']", 'syns_list': "['DU-176B', 'Edoxaban tosilate', 'Edoxaban tosylate']", 'target': 'ENSG00000126218', 'approvedSymbol': 'F10', 'approvedName': 'coagulation factor X', 'mesh_heading': 'Venous Thrombosis',... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1657 | Q6 | What genes does Maraviroc target when it's used to treat HIV-1 infection? | When used to treat HIV-1 infection, the drug Maraviroc targets the gene CCR5. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%maraviroc%" OR LOWER(tradeNames_list) LIKE "%mara... | [{'UUID': 'DrugTargetsIndication121923_text_938389', 'drugName': 'Maraviroc', 'tradeNames_list': "['Celsentri', 'Selzentry']", 'syns_list': "['Maraviroc', 'Rel-Maraviroc', 'UK-427857', 'Uk-427,857']", 'target': 'ENSG00000160791', 'approvedSymbol': 'CCR5', 'approvedName': 'C-C motif chemokine receptor 5', 'mesh_heading'... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.613 | Q6 | What genes does Abiraterone Acetate target when it's used to treat prostate cancer? | When used to treat prostate cancer, the drug Abiraterone Acetate targets the gene CYP17A1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%abiraterone acetate%" OR LOWER(tradeNames_list) L... | [{'UUID': 'DrugTargetsIndication121923_text_1094288', 'drugName': 'Abiraterone Acetate', 'tradeNames_list': "['Yonsa', 'Zytiga']", 'syns_list': "['Abiraterone acetate', 'CB-7630', 'CB7630', 'NSC-748121', 'NSC-749227']", 'target': 'ENSG00000148795', 'approvedSymbol': 'CYP17A1', 'approvedName': 'cytochrome P450 family 17... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.183 | Q6 | What genes does Ribavirin target when it's used to treat depressive disorder? | Ribavirin has not been approved by the FDA as a treatment for depressive disorder, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is IMPDH1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ribavirin%" OR LOWER(tradeNames_list) LIKE "%riba... | [{'UUID': 'DrugTargetsIndication121923_text_937561', 'drugName': 'Ribavirin', 'tradeNames_list': "['Copegus', 'Rebetol', 'Ribapak', 'Ribasphere', 'Ribavarin', 'RibavirinRibofluranosyl Carboxamide', 'Tribavirin', 'Viramid', 'Virazid', 'Virazole']", 'syns_list': "['Cotronak', 'NSC-163039', 'Ribavirin', 'Ribavirin biopart... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.305 | Q6 | What genes does Lorlatinib target when it's used to treat non-small cell lung carcinoma? | When used to treat non-small cell lung carcinoma, the drug Lorlatinib targets the genes ALK and EML4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lorlatinib%" OR LOWER(tradeNames_list) LIKE "%lor... | [{'UUID': 'DrugTargetsIndication121923_text_991071', 'drugName': 'Lorlatinib', 'tradeNames_list': "['Lorbrena']", 'syns_list': "['Lorlatinib', 'PF-06463922']", 'target': 'ENSG00000171094', 'approvedSymbol': 'ALK', 'approvedName': 'ALK receptor tyrosine kinase', 'mesh_heading': 'Carcinoma, Non-Small-Cell Lung', 'efo_ter... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.502 | Q6 | What genes does Cinacalcet Hydrochloride target when it's used to treat Parathyroid Gland Carcinoma? | When used to treat Parathyroid Gland Carcinoma, the drug Cinacalcet Hydrochloride targets the gene CASR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%cinacalcet hydrochloride%" OR LOWER(tradeNames_li... | [{'UUID': 'DrugTargetsIndication121923_text_1149036', 'drugName': 'Cinacalcet Hydrochloride', 'tradeNames_list': "['Mimpara', 'Sensipar']", 'syns_list': "['AMG-073', 'AMG-073 HCL', 'AMG073 HCL', 'AMG073 HYDROCHLORIDECinacalcet hcl', 'Cinacalcet hydrochloride']", 'target': 'ENSG00000036828', 'approvedSymbol': 'CASR', 'a... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1696 | Q6 | What genes does Finerenone target when it's used to treat chronic kidney disease? | When used to treat chronic kidney disease, the drug Finerenone targets the gene NR3C2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%finerenone%" OR LOWER(tradeNames_list) LIKE "%fin... | [{'UUID': 'DrugTargetsIndication121923_text_1094663', 'drugName': 'Finerenone', 'tradeNames_list': "['Kerendia']", 'syns_list': "['BAY 94-8862', 'BAY-94-8862', 'Bay94-8862', 'Finerenone']", 'target': 'ENSG00000151623', 'approvedSymbol': 'NR3C2', 'approvedName': 'nuclear receptor subfamily 3 group C member 2', 'mesh_hea... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1721 | Q6 | What genes does Paclitaxel target when it's used to treat colorectal carcinoma? | Paclitaxel has not been approved by the FDA as a treatment for colorectal carcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are TUBB4B, TUBB1, TUBA3C, TUBA4A, TUBB3, TUBA1A, TUBB4A, TUBB8, TUBB, TUBA1B, TUBA1C, TUBA3E, TUBB2A, TUBB2B, and TUBB6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%paclitaxel%" OR LOWER(tradeNames_list) LIKE "%pac... | [{'UUID': 'DrugTargetsIndication121923_text_836', 'drugName': 'Paclitaxel', 'tradeNames_list': "['Abraxane', 'Pacitaxel', 'Paclitaxel', 'Paxene', 'Taxol', 'Taxol 100']", 'syns_list': "['(-)-paclitaxel', 'ABI-007', 'ABI-007 COMPONENT PACLITAXEL', 'BMS 181339-01BMS-181339-01', 'Capxol', 'Cyclopax', 'DHP 107', 'DHP-107', ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1662 | Q6 | What genes does Midazolam target when it's used to treat epilepsy? | When used to treat epilepsy, the drug Midazolam targets the genes GABRA1, GABRB2, GABRG2, GABRB3, GABRA4, GABRG3, GABRQ, GABRA3, GABRP, GABRD, GABRG1, GABRB1, GABRE, GABRA2, GABRA5, and GABRA6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%midazolam%" OR LOWER(tradeNames_list) LIKE "%mida... | [{'UUID': 'DrugTargetsIndication121923_text_949054', 'drugName': 'Midazolam', 'tradeNames_list': "['Midazolam in 0.8% sodium chloride', 'Midazolam in 0.9% sodium chlorideNayzilam']", 'syns_list': "['Midazolam', 'Midazolam civ', 'USL-261', 'USL261']", 'target': 'ENSG00000022355', 'approvedSymbol': 'GABRA1', 'approvedNam... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1639 | Q6 | What genes does Colchicine target when it's used to treat prostate cancer? | Colchicine has not been approved by the FDA as a treatment for prostate cancer, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are TUBB4B, TUBB1, TUBA3C, TUBA4A, TUBB3, TUBA1A, TUBB4A, TUBB8, TUBB, TUBA1B, TUBA1C, TUBA3E, TUBB2A, TUBB2B, and TUBB6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%colchicine%" OR LOWER(tradeNames_list) LIKE "%col... | [{'UUID': 'DrugTargetsIndication121923_text_70231', 'drugName': 'Colchicine', 'tradeNames_list': "['Colchicine', 'Colcrys', 'Gloperba', 'Mitigare']", 'syns_list': "['(-)-colchicine', 'Colchcine', 'Colchicine', 'Colchicinum', 'ColchineosColchisol', 'NSC-757']", 'target': 'ENSG00000188229', 'approvedSymbol': 'TUBB4B', 'a... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.523 | Q6 | What genes does Vasopressin target when it's used to treat leiomyoma? | Vasopressin has not been approved by the FDA as a treatment for leiomyoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are AVPR2, AVPR1A, and AVPR1B. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%vasopressin%" OR LOWER(tradeNames_list) LIKE "%va... | [{'UUID': 'DrugTargetsIndication121923_text_692598', 'drugName': 'Vasopressin', 'tradeNames_list': "['Beta-Hypophamine', 'Leiormone', 'Pitressin', 'Vasophysin', 'Vasostrict']", 'syns_list': "['Arginine Vasopressin', 'Arginine vasopressin', 'Argipressin or lypressinVasopressin', 'Vasopressin injection', 'Vasopressin, un... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1985 | Q6 | What genes does Dabigatran Etexilate Mesylate target when it's used to treat atrial fibrillation? | When used to treat atrial fibrillation, the drug Dabigatran Etexilate Mesylate targets the gene F2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dabigatran etexilate mesylate%" OR LOWER(tradeNam... | [{'UUID': 'DrugTargetsIndication121923_text_1092393', 'drugName': 'Dabigatran Etexilate Mesylate', 'tradeNames_list': "['Pradaxa']", 'syns_list': "['BIBR 1048 MS', 'BIBR-1048-MS', 'Dabigatran etexilate mesilateDabigatran etexilate mesylate']", 'target': 'ENSG00000180210', 'approvedSymbol': 'F2', 'approvedName': 'coagul... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1078 | Q6 | What genes does Azelastine Hydrochloride target when it's used to treat seasonal allergic rhinitis? | When used to treat seasonal allergic rhinitis, the drug Azelastine Hydrochloride targets the gene HRH1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%azelastine hydrochloride%" OR LOWER(tradeNames_li... | [{'UUID': 'DrugTargetsIndication121923_text_455906', 'drugName': 'Azelastine Hydrochloride', 'tradeNames_list': '[\'Astelin\', \'Astepro\', \'Astepro allergy\', "Azelastine hydrochlorideChildren\'s astepro allergyOptilast", \'Optivar\', \'RhinolastRhinolast allergy\']', 'syns_list': "['A-5610', 'Azelastine hcl', 'Azela... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.482 | Q6 | What genes does Difelikefalin target when it's used to treat Pruritus? | When used to treat Pruritus, the drug Difelikefalin targets the gene OPRK1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%difelikefalin%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_1092272', 'drugName': 'Difelikefalin', 'tradeNames_list': "['Korsuva']", 'syns_list': "['4-PIPERIDINECARBOXYLIC ACID, N1-(D-PHENYLALANYL-D-PHENYLALANYL-D-LEUCYL-D-LYSYL)-4-AMINO-CR-845', 'CR845', 'Cr-845 acetate', 'Difelikefalin', 'Difelikefalin acetateFE-202845', 'FE202845',... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.160 | Q6 | What genes does Fluorouracil target when it's used to treat signet ring cell carcinoma? | Fluorouracil has not been approved by the FDA as a treatment for signet ring cell carcinoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is TYMS. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fluorouracil%" OR LOWER(tradeNames_list) LIKE "%f... | [{'UUID': 'DrugTargetsIndication121923_text_919407', 'drugName': 'Fluorouracil', 'tradeNames_list': "['5.f.u.', 'Accusite', 'Actikerall', 'Adrucil', 'Carac', 'Efudex', 'EfudixFluoro-uracil roche', 'Fluoroplex', 'Fluorouracil', 'Tolak']", 'syns_list': "['5 FU', '5-FU', '5-Fluorouracil', '5-fluoruracil', 'FluorouracilFlu... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1253 | Q6 | What genes does Abiraterone Acetate target when it's used to treat prostate carcinoma? | When used to treat prostate carcinoma, the drug Abiraterone Acetate targets the gene CYP17A1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%abiraterone acetate%" OR LOWER(tradeNames_list) L... | [{'UUID': 'DrugTargetsIndication121923_text_1094287', 'drugName': 'Abiraterone Acetate', 'tradeNames_list': "['Yonsa', 'Zytiga']", 'syns_list': "['Abiraterone acetate', 'CB-7630', 'CB7630', 'NSC-748121', 'NSC-749227']", 'target': 'ENSG00000148795', 'approvedSymbol': 'CYP17A1', 'approvedName': 'cytochrome P450 family 17... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1205 | Q6 | What genes does Phenylephrine Hydrochloride target when it's used to treat common cold? | When used to treat common cold, the drug Phenylephrine Hydrochloride targets the genes ADRA1A, ADRA1D, and ADRA1B. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%phenylephrine hydrochloride%" OR LOWER(tradeNames... | [{'UUID': 'DrugTargetsIndication121923_text_416702', 'drugName': 'Phenylephrine Hydrochloride', 'tradeNames_list': "['Afrin 4 hour nasal spray', 'Biomydrin', 'Biorphen', 'Fenilfar', 'FenoxMydfrin', 'Nazex', 'Neo-synephrine', 'Neosynephrine', 'NostrilNurofen sinus pain relief', 'Phenylephrine hydrochloride', 'PrefrinVaz... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.17 | Q6 | What genes does Prednisone target when it's used to treat trichinosis? | When used to treat trichinosis, the drug Prednisone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%prednisone%" OR LOWER(tradeNames_list) LIKE "%pre... | [{'UUID': 'DrugTargetsIndication121923_text_218697', 'drugName': 'Prednisone', 'tradeNames_list': "['Cortan', 'Cortancyl', 'Decortisyl', 'Delta-dome', 'Deltasone', 'FernisoneLiquid pred', 'Lodotra', 'Meticorten', 'Orasone', 'Paracort', 'Prednicen-mPrednisone', 'Prednisone intensol', 'Rayos', 'Servisone', 'Sterapred']",... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1550 | Q6 | What genes does Rivaroxaban target when it's used to treat pulmonary embolism? | When used to treat pulmonary embolism, the drug Rivaroxaban targets the gene F10. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%rivaroxaban%" OR LOWER(tradeNames_list) LIKE "%ri... | [{'UUID': 'DrugTargetsIndication121923_text_708857', 'drugName': 'Rivaroxaban', 'tradeNames_list': "['Xarelto']", 'syns_list': "['BAY 59-7939', 'BAY-59-7939', 'JNJ-39039039', 'JNJ39039039', 'Rivaroxaban']", 'target': 'ENSG00000126218', 'approvedSymbol': 'F10', 'approvedName': 'coagulation factor X', 'mesh_heading': 'Pu... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1081 | Q6 | What genes does Metoclopramide Hydrochloride target when it's used to treat gastroparesis? | When used to treat gastroparesis, the drug Metoclopramide Hydrochloride targets the genes DRD2, HTR3A, and HTR4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%metoclopramide hydrochloride%" OR LOWER(tradeName... | [{'UUID': 'DrugTargetsIndication121923_text_199704', 'drugName': 'Metoclopramide Hydrochloride', 'tradeNames_list': '[\'"clopra-""yellow"""\', \'Clopra\', \'Clopra-"Yellow"\', \'Gastrese l.a.Gastrobid continus\', \'Gastroflux\', \'Gastromax\', \'Gimoti\', \'MaxolonMaxolon sr\', \'Metoclomex\', \'Metoclopramide hydrochl... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1972 | Q6 | What genes does Amlodipine Besylate target when it's used to treat familial hypercholesterolemia? | When used to treat familial hypercholesterolemia, the drug Amlodipine Besylate targets the genes CACNA1C, CACNA1S, CACNA1D, and CACNA1F. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%amlodipine besylate%" OR LOWER(tradeNames_list) L... | [{'UUID': 'DrugTargetsIndication121923_text_1043740', 'drugName': 'Amlodipine Besylate', 'tradeNames_list': "['Amlodipine besylate', 'Norliqva', 'Norvasc']", 'syns_list': "['Amlodipine (as besilate)', 'Amlodipine benzenesulfonateAmlodipine besilate', 'Amlodipine besylate', 'Amlor', 'AntacalLodipressin', 'Monopina', 'NS... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.552 | Q6 | What genes does Prednisone target when it's used to treat meningeal tuberculosis? | When used to treat meningeal tuberculosis, the drug Prednisone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%prednisone%" OR LOWER(tradeNames_list) LIKE "%pre... | [{'UUID': 'DrugTargetsIndication121923_text_218702', 'drugName': 'Prednisone', 'tradeNames_list': "['Cortan', 'Cortancyl', 'Decortisyl', 'Delta-dome', 'Deltasone', 'FernisoneLiquid pred', 'Lodotra', 'Meticorten', 'Orasone', 'Paracort', 'Prednicen-mPrednisone', 'Prednisone intensol', 'Rayos', 'Servisone', 'Sterapred']",... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1554 | Q6 | What genes does Lisdexamfetamine Dimesylate target when it's used to treat attention deficit hyperactivity disorder? | When used to treat attention deficit hyperactivity disorder, the drug Lisdexamfetamine Dimesylate targets the genes SLC6A2, SLC18A2, and SLC6A3. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lisdexamfetamine dimesylate%" OR LOWER(tradeNames... | [{'UUID': 'DrugTargetsIndication121923_text_419192', 'drugName': 'Lisdexamfetamine Dimesylate', 'tradeNames_list': "['Elvanse', 'Elvanse adult', 'Vyvanse']", 'syns_list': "['Lisdexamfetamine dimesilate', 'Lisdexamfetamine dimesylateLisdexamfetamine dimethanesulfonate', 'Lisdexamfetamine mesilateLisdexamphetamine dimesi... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.665 | Q6 | What genes does Leuprolide Acetate target when it's used to treat prostate adenocarcinoma? | When used to treat prostate adenocarcinoma, the drug Leuprolide Acetate targets the gene GNRHR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%leuprolide acetate%" OR LOWER(tradeNames_list) LI... | [{'UUID': 'DrugTargetsIndication121923_text_1097113', 'drugName': 'Leuprolide Acetate', 'tradeNames_list': "['Carcinil', 'Eligard', 'Eligard kit', 'Fensolvi kit', 'Leuprolide acetateLeuprorelin', 'Lupron', 'Lupron Depot Ped', 'Lupron depotLupron depot-ped', 'Lupron depot-ped kit', 'Lutrate depot kit', 'Viadur']", 'syns... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1626 | Q6 | What genes does Dexamethasone target when it's used to treat Waldenstrom macroglobulinemia? | Dexamethasone has not been approved by the FDA as a treatment for Waldenstrom macroglobulinemia, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dexamethasone%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_227693', 'drugName': 'Dexamethasone', 'tradeNames_list': "['Aeroseb-dex', 'Dalalone', 'Decaderm', 'Decadron', 'Decadron-75', 'DecasprayDexacortisyl', 'Dexafree', 'Dexamethasone', 'Dexamethasone intensolDexone', 'Dexone 0.5', 'Dexone 0.75', 'Dexone 1.5', 'Dexone 4', 'DexsolDex... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1028 | Q6 | What genes does Torsemide target when it's used to treat cardiovascular disease? | When used to treat cardiovascular disease, the drug Torsemide targets the gene SLC12A1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%torsemide%" OR LOWER(tradeNames_list) LIKE "%tors... | [{'UUID': 'DrugTargetsIndication121923_text_1149088', 'drugName': 'Torsemide', 'tradeNames_list': "['Demadex', 'Soaanz', 'Torem 10', 'Torem 2.5', 'Torem 5', 'Torsemide']", 'syns_list': "['AC-4464', 'AC4464', 'BM-02.015', 'BM-02015', 'BM02.015', 'LupracTorasemide', 'Torasemide anhydrous', 'Torsemide', 'Upcard']", 'targe... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1994 | Q6 | What genes does Tiotropium Bromide target when it's used to treat Renal insufficiency? | Tiotropium Bromide has not been approved by the FDA as a treatment for Renal insufficiency, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is CHRM3. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%tiotropium bromide%" OR LOWER(tradeNames_list) LI... | [{'UUID': 'DrugTargetsIndication121923_text_857907', 'drugName': 'Tiotropium Bromide', 'tradeNames_list': "['Spiriva', 'Spiriva respimat']", 'syns_list': "['BA 679 BR', 'BA-679 BR', 'BA-679-BR', 'BA-679BR', 'Tiotropium bromideTiotropium bromide anhydrous', 'Tiotropium bromide hydrateTiotropium bromide monohydrate']", '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1519 | Q6 | What genes does Testosterone target when it's used to treat sarcopenia? | Testosterone has not been approved by the FDA as a treatment for sarcopenia, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is AR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%testosterone%" OR LOWER(tradeNames_list) LIKE "%t... | [{'UUID': 'DrugTargetsIndication121923_text_922690', 'drugName': 'Testosterone', 'tradeNames_list': "['Androderm', 'Androgel', 'Androgel 1%', 'Andropatch', 'Axiron', 'FortestaIntrinsa', 'Natesto', 'Striant', 'Striant sr', 'Testim', 'Testim 1%Testoderm', 'Testoderm tts', 'Testogel', 'Testopatch', 'Testopel', 'TestoralTe... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.968 | Q6 | What genes does Gemcitabine Hydrochloride target when it's used to treat non-small cell lung carcinoma? | When used to treat non-small cell lung carcinoma, the drug Gemcitabine Hydrochloride targets the genes POLA1, POLD4, POLD3, POLD1, POLD2, POLE, POLA2, PRIM1, PRIM2, POLE2, POLE3, RRM1, RRM2B, and RRM2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%gemcitabine hydrochloride%" OR LOWER(tradeNames_l... | [{'UUID': 'DrugTargetsIndication121923_text_756071', 'drugName': 'Gemcitabine Hydrochloride', 'tradeNames_list': "['Gemcitabine hydrochloride', 'Gemzar', 'Infugem']", 'syns_list': "['Gemcitabine (as hydrochloride)', 'Gemcitabine hclGemcitabine hydrochloride', 'Gemzar', 'LY-188011LY-188011 HYDROCHLORIDE', 'LY188011 HYDR... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1883 | Q6 | What genes does Aclidinium Bromide target when it's used to treat Airway obstruction? | When used to treat Airway obstruction, the drug Aclidinium Bromide targets the gene CHRM3. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%aclidinium bromide%" OR LOWER(tradeNames_list) LI... | [{'UUID': 'DrugTargetsIndication121923_text_857457', 'drugName': 'Aclidinium Bromide', 'tradeNames_list': "['Eklira', 'Tudorza pressair']", 'syns_list': "['14115700', 'Aclidinium bromide', 'Genuair', 'LAS 34273LAS 34273 MICRONIZED', 'LAS W-330', 'LAS-34273', 'LAS-34273 MICRONIZEDLAS-W-330']", 'target': 'ENSG00000133019... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
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