uuid stringlengths 4 8 | template_uuid stringclasses 40
values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 133 622 | execution_results stringlengths 2 1.14M | query_type stringclasses 2
values | sql_category stringclasses 26
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Q6.505 | Q6 | What genes does Bortezomib target when it's used to treat lymphoproliferative syndrome? | Bortezomib has not been approved by the FDA as a treatment for lymphoproliferative syndrome, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are PSMD1, PSMB2, PSMB1, PSMB5, PSMB8, PSMB9, PSMB6, PSMD14, PSMA1, PSMA2, PSMA3, PSMA4, PSMA5, PSMA6, PSMA7, PSMA8, PSMB1... | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%bortezomib%" OR LOWER(tradeNames_list) LIKE "%bor... | [{'UUID': 'DrugTargetsIndication121923_text_342326', 'drugName': 'Bortezomib', 'tradeNames_list': "['Velcade']", 'syns_list': "['Bortezomib', 'Bortezomib accord', 'Bortezomib hydrate', 'LDP-341NSC-681239', 'PS-341', 'Velcade']", 'target': 'ENSG00000126067', 'approvedSymbol': 'PSMB2', 'approvedName': 'proteasome 20S sub... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.342 | Q6 | What genes does Tazarotene target when it's used to treat acne? | When used to treat acne, the drug Tazarotene targets the genes RARG, RARB, and RARA. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%tazarotene%" OR LOWER(tradeNames_list) LIKE "%taz... | [{'UUID': 'DrugTargetsIndication121923_text_1055500', 'drugName': 'Tazarotene', 'tradeNames_list': "['Arazlo', 'Avage', 'Fabior', 'Tazorac', 'Zorac']", 'syns_list': "['AGN 190168', 'AGN-190168', 'Idp-123', 'Tazarotene']", 'target': 'ENSG00000077092', 'approvedSymbol': 'RARB', 'approvedName': 'retinoic acid receptor bet... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1198 | Q6 | What genes does Dextroamphetamine target when it's used to treat arteriosclerosis disorder? | When used to treat arteriosclerosis disorder, the drug Dextroamphetamine targets the genes SLC6A2, SLC18A2, and SLC6A3. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dextroamphetamine%" OR LOWER(tradeNames_list) LIK... | [{'UUID': 'DrugTargetsIndication121923_text_418426', 'drugName': 'Dextroamphetamine', 'tradeNames_list': "['Dexedrine', 'Dextrostat', 'Xelstrym']", 'syns_list': "['Amfetamine, (s)-', 'Amphetamine, d-', 'D-amphetamine', 'DexamfetamineDexampex', 'Dexamphetamine', 'Dexedrine', 'Dexidrine', 'DextroamphetamineDextroamphetam... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.29 | Q6 | What genes does Vasopressin target when it's used to treat Sepsis? | When used to treat Sepsis, the drug Vasopressin targets the genes AVPR2, AVPR1A, and AVPR1B. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%vasopressin%" OR LOWER(tradeNames_list) LIKE "%va... | [{'UUID': 'DrugTargetsIndication121923_text_692606', 'drugName': 'Vasopressin', 'tradeNames_list': "['Beta-Hypophamine', 'Leiormone', 'Pitressin', 'Vasophysin', 'Vasostrict']", 'syns_list': "['Arginine Vasopressin', 'Arginine vasopressin', 'Argipressin or lypressinVasopressin', 'Vasopressin injection', 'Vasopressin, un... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1227 | Q6 | What genes does Dasatinib target when it's used to treat neoplasm? | When used to treat neoplasm, the drug Dasatinib targets the genes ABL1, BCR, HCK, SRC, LYN, KIT, PDGFRB, EPHA2, FRK, FYN, LCK, YES1, BLK, FGR, and SRMS. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dasatinib%" OR LOWER(tradeNames_list) LIKE "%dasa... | [{'UUID': 'DrugTargetsIndication121923_text_714299', 'drugName': 'Dasatinib', 'tradeNames_list': "['Dasatinib', 'Sprycel']", 'syns_list': "['BMS-354825', 'BMS-354825 HYDRATE', 'BMS-354825-03', 'DasatinibDasatinib anhydrous', 'Dasatinib hydrate', 'Dasatinib monohydrateNSC-759877']", 'target': 'ENSG00000097007', 'approve... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1434 | Q6 | What genes does Midazolam target when it's used to treat Sepsis? | Midazolam has not been approved by the FDA as a treatment for Sepsis, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are GABRA1, GABRB2, GABRG2, GABRB3, GABRA4, GABRG3, GABRQ, GABRA3, GABRP, GABRD, GABRG1, GABRB1, GABRE, GABRA2, GABRA5, and GABRA6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%midazolam%" OR LOWER(tradeNames_list) LIKE "%mida... | [{'UUID': 'DrugTargetsIndication121923_text_948963', 'drugName': 'Midazolam', 'tradeNames_list': "['Midazolam in 0.8% sodium chloride', 'Midazolam in 0.9% sodium chlorideNayzilam']", 'syns_list': "['Midazolam', 'Midazolam civ', 'USL-261', 'USL261']", 'target': 'ENSG00000022355', 'approvedSymbol': 'GABRA1', 'approvedNam... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1954 | Q6 | What genes does Lenvatinib target when it's used to treat prostate cancer? | Lenvatinib has not been approved by the FDA as a treatment for prostate cancer, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are KDR, FLT1, and FLT4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lenvatinib%" OR LOWER(tradeNames_list) LIKE "%len... | [{'UUID': 'DrugTargetsIndication121923_text_690772', 'drugName': 'Lenvatinib', 'tradeNames_list': "['Kisplyx', 'Lenvima']", 'syns_list': "['E-7080', 'ER-203492-00', 'Lenvatinib']", 'target': 'ENSG00000128052', 'approvedSymbol': 'KDR', 'approvedName': 'kinase insert domain receptor', 'mesh_heading': 'Prostatic Neoplasms... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.954 | Q6 | What genes does Doxycycline target when it's used to treat bacterial disease? | When used to treat bacterial disease, the drug Doxycycline targets the genes MMP7, MMP1, MMP13, and MMP8. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%doxycycline%" OR LOWER(tradeNames_list) LIKE "%do... | [{'UUID': 'DrugTargetsIndication121923_text_1038218', 'drugName': 'Doxycycline', 'tradeNames_list': "['Doxychel', 'Doxycycline', 'Monodox', 'Oracea', 'Vibramycin']", 'syns_list': "['Doxirobe', 'Doxycycline', 'Doxycycline monohydrate', 'Doxylin', 'GS-3065Supracyclin', 'Xyrosa']", 'target': 'ENSG00000137673', 'approvedSy... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.172 | Q6 | What genes does Patisiran Sodium target when it's used to treat polyneuropathy? | When used to treat polyneuropathy, the drug Patisiran Sodium targets the gene TTR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%patisiran sodium%" OR LOWER(tradeNames_list) LIKE... | [{'UUID': 'DrugTargetsIndication121923_text_1097700', 'drugName': 'Patisiran Sodium', 'tradeNames_list': "['Onpattro']", 'syns_list': "['Patisiran sodium']", 'target': 'ENSG00000118271', 'approvedSymbol': 'TTR', 'approvedName': 'transthyretin', 'mesh_heading': 'Polyneuropathies', 'efo_term': 'polyneuropathy', 'yearOfFi... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1406 | Q6 | What genes does Leuprolide Acetate target when it's used to treat uterine fibroid? | Leuprolide Acetate has not been approved by the FDA as a treatment for uterine fibroid, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is GNRHR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%leuprolide acetate%" OR LOWER(tradeNames_list) LI... | [{'UUID': 'DrugTargetsIndication121923_text_1097106', 'drugName': 'Leuprolide Acetate', 'tradeNames_list': "['Carcinil', 'Eligard', 'Eligard kit', 'Fensolvi kit', 'Leuprolide acetateLeuprorelin', 'Lupron', 'Lupron Depot Ped', 'Lupron depotLupron depot-ped', 'Lupron depot-ped kit', 'Lutrate depot kit', 'Viadur']", 'syns... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1207 | Q6 | What genes does Sorafenib Tosylate target when it's used to treat thyroid cancer? | When used to treat thyroid cancer, the drug Sorafenib Tosylate targets the genes KDR, BRAF, FLT1, FLT3, KIT, FLT4, PDGFRB, RAF1, and RET. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%sorafenib tosylate%" OR LOWER(tradeNames_list) LI... | [{'UUID': 'DrugTargetsIndication121923_text_683542', 'drugName': 'Sorafenib Tosylate', 'tradeNames_list': "['Nexavar']", 'syns_list': "['BAY 54-9085', 'BAY-54-9085', 'Sorafenib tosilate', 'Sorafenib tosylate']", 'target': 'ENSG00000157764', 'approvedSymbol': 'BRAF', 'approvedName': 'B-Raf proto-oncogene, serine/threoni... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1263 | Q6 | What genes does Metformin Hydrochloride target when it's used to treat type 2 diabetes mellitus? | When used to treat type 2 diabetes mellitus, the drug Metformin Hydrochloride targets the genes MT-ND6, NDUFA10, NDUFS8, MT-ND4L, NDUFA6, MT-ND1, NDUFB6, NDUFA4, NDUFA11, NDUFB7, MT-ND2, NDUFS2, MT-ND5, NDUFA8, NDUFB5, MT-ND4, MT-ND3, NDUFAB1, NDUFA1, NDUFS4, NDUFB3, NDUFC1, NDUFA2, NDUFS5, NDUFS7, NDUFS6, NDUFB1, NDUF... | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%metformin hydrochloride%" OR LOWER(tradeNames_lis... | [{'UUID': 'DrugTargetsIndication121923_text_1149709', 'drugName': 'Metformin Hydrochloride', 'tradeNames_list': "['Bolamyn sr', 'Diagemet xl', 'Fortamet', 'Glucamet 500', 'Glucamet 850Glucient sr', 'Glucophage', 'Glucophage sr', 'Glucophage xr', 'GlumetzaGlyformin', 'Janumet', 'Ledermetin', 'Metabet sr', 'Metformin hyd... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1400 | Q6 | What genes does Histrelin Acetate target when it's used to treat prostate cancer? | When used to treat prostate cancer, the drug Histrelin Acetate targets the gene GNRHR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%histrelin acetate%" OR LOWER(tradeNames_list) LIK... | [{'UUID': 'DrugTargetsIndication121923_text_1097121', 'drugName': 'Histrelin Acetate', 'tradeNames_list': "['Supprelin', 'Supprelin la', 'Vantas']", 'syns_list': "['Histrelin acetate']", 'target': 'ENSG00000109163', 'approvedSymbol': 'GNRHR', 'approvedName': 'gonadotropin releasing hormone receptor', 'mesh_heading': 'P... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.920 | Q6 | What genes does Dimethyl Fumarate target when it's used to treat chronic progressive multiple sclerosis? | Dimethyl Fumarate has not been approved by the FDA as a treatment for chronic progressive multiple sclerosis, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is KEAP1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dimethyl fumarate%" OR LOWER(tradeNames_list) LIK... | [{'UUID': 'DrugTargetsIndication121923_text_1055753', 'drugName': 'Dimethyl Fumarate', 'tradeNames_list': "['Tecfidera']", 'syns_list': "['AZL 0 211089', 'AZL O 211089', 'AZL-0211089', 'AZL-O-211089', 'BG 00012BG 12', 'BG-00012', 'BG-12', 'BG00012', 'Dimethyl fumar', 'Dimethyl fumarateFAG-201', 'FP-187', 'FP187', 'Fuma... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.497 | Q6 | What genes does Idelalisib target when it's used to treat non-Hodgkins lymphoma? | When used to treat non-Hodgkins lymphoma, the drug Idelalisib targets the gene PIK3CD. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%idelalisib%" OR LOWER(tradeNames_list) LIKE "%ide... | [{'UUID': 'DrugTargetsIndication121923_text_858493', 'drugName': 'Idelalisib', 'tradeNames_list': "['Zydelig']", 'syns_list': "['CAL-101', 'GS-1101', 'GS-11CAL-101', 'Idelalisib']", 'target': 'ENSG00000171608', 'approvedSymbol': 'PIK3CD', 'approvedName': 'phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.962 | Q6 | What genes does Dantrolene Sodium target when it's used to treat multiple sclerosis? | When used to treat multiple sclerosis, the drug Dantrolene Sodium targets the genes RYR3 and RYR1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dantrolene sodium%" OR LOWER(tradeNames_list) LIK... | [{'UUID': 'DrugTargetsIndication121923_text_1100268', 'drugName': 'Dantrolene Sodium', 'tradeNames_list': "['Dantrium', 'Dantrolene sodium', 'Revonto', 'Ryanodex']", 'syns_list': "['Dantamacrin', 'Dantrolen', 'Dantrolene sodiumDantrolene sodium heptahydrate', 'Dantrolene sodium hydrateDantrolene sodium salt hemiheptahy... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1106 | Q6 | What genes does Granisetron target when it's used to treat Nausea? | When used to treat Nausea, the drug Granisetron targets the gene HTR3A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%granisetron%" OR LOWER(tradeNames_list) LIKE "%gr... | [{'UUID': 'DrugTargetsIndication121923_text_205762', 'drugName': 'Granisetron', 'tradeNames_list': "['Kytril', 'Sancuso', 'Sustol']", 'syns_list': "['APF-530', 'APF530', 'BRL 43694', 'BRL-43694', 'Granisetron', 'LY-278584']", 'target': 'ENSG00000166736', 'approvedSymbol': 'HTR3A', 'approvedName': '5-hydroxytryptamine r... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1041 | Q6 | What genes does Diclofenac target when it's used to treat eye inflammation? | When used to treat eye inflammation, the drug Diclofenac targets the genes PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%diclofenac%" OR LOWER(tradeNames_list) LIKE "%dic... | [{'UUID': 'DrugTargetsIndication121923_text_837130', 'drugName': 'Diclofenac', 'tradeNames_list': "['Cambia', 'Voltaren', 'Voltaren Ophthalmic', 'Voltaren Xr', 'ZorvolexZorvolex capsules']", 'syns_list': "['Arthrotec', 'Cataflam', 'Diclofenac', 'Diclofenac acidDiclofenac free acid', 'LAS-41007', 'LAS41007', 'Las41007',... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.594 | Q6 | What genes does Cabazitaxel target when it's used to treat metastatic prostate cancer? | When used to treat metastatic prostate cancer, the drug Cabazitaxel targets the genes TUBB4B, TUBB1, TUBA3C, TUBA4A, TUBB3, TUBA1A, TUBB4A, TUBB8, TUBB, TUBA1B, TUBA1C, TUBA3E, TUBB2A, TUBB2B, and TUBB6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%cabazitaxel%" OR LOWER(tradeNames_list) LIKE "%ca... | [{'UUID': 'DrugTargetsIndication121923_text_67999', 'drugName': 'Cabazitaxel', 'tradeNames_list': "['Jevtana', 'Jevtana kit']", 'syns_list': "['Cabazitaxel', 'Cabazitaxel acetonate', 'Jevtana', 'NSC-761432', 'TXD 258TXD-258', 'XRP 6258', 'XRP-6258']", 'target': 'ENSG00000188229', 'approvedSymbol': 'TUBB4B', 'approvedNa... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.757 | Q6 | What genes does Prednisone target when it's used to treat dermatitis herpetiformis? | When used to treat dermatitis herpetiformis, the drug Prednisone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%prednisone%" OR LOWER(tradeNames_list) LIKE "%pre... | [{'UUID': 'DrugTargetsIndication121923_text_218704', 'drugName': 'Prednisone', 'tradeNames_list': "['Cortan', 'Cortancyl', 'Decortisyl', 'Delta-dome', 'Deltasone', 'FernisoneLiquid pred', 'Lodotra', 'Meticorten', 'Orasone', 'Paracort', 'Prednicen-mPrednisone', 'Prednisone intensol', 'Rayos', 'Servisone', 'Sterapred']",... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.664 | Q6 | What genes does Pitavastatin Magnesium target when it's used to treat Abnormal circulating lipid concentration? | When used to treat Abnormal circulating lipid concentration, the drug Pitavastatin Magnesium targets the gene HMGCR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%pitavastatin magnesium%" OR LOWER(tradeNames_list... | [{'UUID': 'DrugTargetsIndication121923_text_1104303', 'drugName': 'Pitavastatin Magnesium', 'tradeNames_list': "['Zypitamag']", 'syns_list': "['Pitavastatin magnesium']", 'target': 'ENSG00000113161', 'approvedSymbol': 'HMGCR', 'approvedName': '3-hydroxy-3-methylglutaryl-CoA reductase', 'mesh_heading': 'Dyslipidemias', ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.237 | Q6 | What genes does Argatroban target when it's used to treat Thrombocytopenia? | When used to treat Thrombocytopenia, the drug Argatroban targets the gene F2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%argatroban%" OR LOWER(tradeNames_list) LIKE "%arg... | [{'UUID': 'DrugTargetsIndication121923_text_1093395', 'drugName': 'Argatroban', 'tradeNames_list': "['Acova', 'Argatroban', 'Argatroban in dextroseArgatroban in sodium chloride']", 'syns_list': "['Argatroban', 'Argatroban anhydrous', 'Argatroban hydrateArgatroban monohydrate', 'Argipidine', 'DK-7419', 'GN-1600', 'GN160... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.739 | Q6 | What genes does Fenofibrate target when it's used to treat cardiovascular disease? | When used to treat cardiovascular disease, the drug Fenofibrate targets the gene PPARA. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fenofibrate%" OR LOWER(tradeNames_list) LIKE "%fe... | [{'UUID': 'DrugTargetsIndication121923_text_244026', 'drugName': 'Fenofibrate', 'tradeNames_list': "['Antara', 'Antara (micronized)', 'Fenofibrate', 'Fenofibrate (micronized)Fenogal', 'Fenoglide', 'Lipantil', 'Lipantil micro 200Lipantil micro 267', 'Lipantil micro 67', 'Lipidil', 'LipofenSupralip 160', 'Tricor', 'Trico... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1989 | Q6 | What genes does Betamethasone Dipropionate target when it's used to treat Nasal congestion? | When used to treat Nasal congestion, the drug Betamethasone Dipropionate targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%betamethasone dipropionate%" OR LOWER(tradeNames_... | [{'UUID': 'DrugTargetsIndication121923_text_220890', 'drugName': 'Betamethasone Dipropionate', 'tradeNames_list': "['Alphatrex', 'Betamethasone dipropionate', 'Diprolene', 'Diprolene afDiprosone', 'Sernivo']", 'syns_list': "['Betamethasone (as dipropionate)', 'Betamethasone 17,21-dipropionateBetamethasone dipropionate'... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1633 | Q6 | What genes does Torsemide target when it's used to treat myocardial infarction? | When used to treat myocardial infarction, the drug Torsemide targets the gene SLC12A1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%torsemide%" OR LOWER(tradeNames_list) LIKE "%tors... | [{'UUID': 'DrugTargetsIndication121923_text_1149091', 'drugName': 'Torsemide', 'tradeNames_list': "['Demadex', 'Soaanz', 'Torem 10', 'Torem 2.5', 'Torem 5', 'Torsemide']", 'syns_list': "['AC-4464', 'AC4464', 'BM-02.015', 'BM-02015', 'BM02.015', 'LupracTorasemide', 'Torasemide anhydrous', 'Torsemide', 'Upcard']", 'targe... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1166 | Q6 | What genes does Fosaprepitant Dimeglumine target when it's used to treat post operative nausea and vomiting? | When used to treat post operative nausea and vomiting, the drug Fosaprepitant Dimeglumine targets the gene TACR1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fosaprepitant dimeglumine%" OR LOWER(tradeNames_l... | [{'UUID': 'DrugTargetsIndication121923_text_1073180', 'drugName': 'Fosaprepitant Dimeglumine', 'tradeNames_list': "['Emend', 'Fosaprepitant dimeglumine']", 'syns_list': "['Fosaprepitant (as dimeglumine)', 'Fosaprepitant dimeglumineFosaprepitant meglumine', 'MK-0517']", 'target': 'ENSG00000115353', 'approvedSymbol': 'TA... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1471 | Q6 | What genes does Hydromorphone Hydrochloride target when it's used to treat osteoarthritis, hip? | Hydromorphone Hydrochloride has not been approved by the FDA as a treatment for osteoarthritis, hip, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is OPRM1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%hydromorphone hydrochloride%" OR LOWER(tradeNames... | [{'UUID': 'DrugTargetsIndication121923_text_792047', 'drugName': 'Hydromorphone Hydrochloride', 'tradeNames_list': "['Dilaudid', 'Dilaudid-hp', 'Exalgo', 'Hydromorphone hydrochloridePalladone', 'Palladone-sr']", 'syns_list': "['Dihydromorphinone hydrochloride', 'Hydromorphone HCl', 'Hydromorphone hclHydromorphone hydro... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1913 | Q6 | What genes does Ganaxolone target when it's used to treat West syndrome? | When used to treat West syndrome, the drug Ganaxolone targets the genes GABRA1, GABRB2, GABRG2, GABRB3, GABRA4, GABRG3, GABRQ, GABRA3, GABRP, GABRD, GABRG1, GABRB1, GABRE, GABRA2, GABRA5, and GABRA6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ganaxolone%" OR LOWER(tradeNames_list) LIKE "%gan... | [{'UUID': 'DrugTargetsIndication121923_text_945946', 'drugName': 'Ganaxolone', 'tradeNames_list': "['Ztalmy']", 'syns_list': "['CCD 1042', 'CCD-1042', 'DEA NO. 2401', 'Ganaxolone', 'Ztalmy']", 'target': 'ENSG00000022355', 'approvedSymbol': 'GABRA1', 'approvedName': 'gamma-aminobutyric acid type A receptor subunit alpha... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1628 | Q6 | What genes does Mometasone Furoate target when it's used to treat obstructive sleep apnea? | Mometasone Furoate has not been approved by the FDA as a treatment for obstructive sleep apnea, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%mometasone furoate%" OR LOWER(tradeNames_list) LI... | [{'UUID': 'DrugTargetsIndication121923_text_242030', 'drugName': 'Mometasone Furoate', 'tradeNames_list': "['Asmanex', 'Asmanex hfa', 'Asmanex twisthaler', 'EloconMometasone furoate', 'Nasonex', 'Nasonex 24hr allergy', 'Sinuva']", 'syns_list': "['LAS-41002', 'LAS41002', 'LYR-210', 'LYR210', 'Lyr-210', 'MometasoneMometa... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.943 | Q6 | What genes does Prednisolone Acetate target when it's used to treat inflammation? | When used to treat inflammation, the drug Prednisolone Acetate targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%prednisolone acetate%" OR LOWER(tradeNames_list) ... | [{'UUID': 'DrugTargetsIndication121923_text_243778', 'drugName': 'Prednisolone Acetate', 'tradeNames_list': "['Econopred', 'Flo-pred', 'Meticortelone', 'Omnipred', 'Pred forte', 'Pred ftePred mild', 'Prednisolone acetate', 'Sterane', 'Ultracortenol']", 'syns_list': "['NSC-10966', 'Prednisolone 21-acetate', 'Prednisolon... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1219 | Q6 | What genes does Paclitaxel target when it's used to treat undifferentiated carcinoma? | When used to treat undifferentiated carcinoma, the drug Paclitaxel targets the genes TUBB4B, TUBB1, TUBA3C, TUBA4A, TUBB3, TUBA1A, TUBB4A, TUBB8, TUBB, TUBA1B, TUBA1C, TUBA3E, TUBB2A, TUBB2B, and TUBB6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%paclitaxel%" OR LOWER(tradeNames_list) LIKE "%pac... | [{'UUID': 'DrugTargetsIndication121923_text_935', 'drugName': 'Paclitaxel', 'tradeNames_list': "['Abraxane', 'Pacitaxel', 'Paclitaxel', 'Paxene', 'Taxol', 'Taxol 100']", 'syns_list': "['(-)-paclitaxel', 'ABI-007', 'ABI-007 COMPONENT PACLITAXEL', 'BMS 181339-01BMS-181339-01', 'Capxol', 'Cyclopax', 'DHP 107', 'DHP-107', ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1074 | Q6 | What genes does Fludarabine Phosphate target when it's used to treat vasculitis? | Fludarabine Phosphate has not been approved by the FDA as a treatment for vasculitis, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are POLA1, POLD4, POLD3, POLD1, POLD2, POLE, POLA2, PRIM1, PRIM2, POLE2, POLE3, RRM1, RRM2B, and RRM2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fludarabine phosphate%" OR LOWER(tradeNames_list)... | [{'UUID': 'DrugTargetsIndication121923_text_754524', 'drugName': 'Fludarabine Phosphate', 'tradeNames_list': "['Fludara', 'Fludarabine phosphate', 'Oforta']", 'syns_list': '[\'2-f-ara-amp\', \'2-f-araa\', \'2-fluoro ara-a\', \'2-fluorovidarabineFludarabine\', "Fludarabine 5\'-monophosphateFludarabine monophosphateFluda... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.111 | Q6 | What genes does Prednisone target when it's used to treat exfoliative dermatitis? | When used to treat exfoliative dermatitis, the drug Prednisone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%prednisone%" OR LOWER(tradeNames_list) LIKE "%pre... | [{'UUID': 'DrugTargetsIndication121923_text_218700', 'drugName': 'Prednisone', 'tradeNames_list': "['Cortan', 'Cortancyl', 'Decortisyl', 'Delta-dome', 'Deltasone', 'FernisoneLiquid pred', 'Lodotra', 'Meticorten', 'Orasone', 'Paracort', 'Prednicen-mPrednisone', 'Prednisone intensol', 'Rayos', 'Servisone', 'Sterapred']",... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1944 | Q6 | What genes does Temsirolimus target when it's used to treat oligodendroglioma? | Temsirolimus has not been approved by the FDA as a treatment for oligodendroglioma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is FKBP1A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%temsirolimus%" OR LOWER(tradeNames_list) LIKE "%t... | [{'UUID': 'DrugTargetsIndication121923_text_1090798', 'drugName': 'Temsirolimus', 'tradeNames_list': "['Torisel']", 'syns_list': "['CCI-779', 'Temsirolimus']", 'target': 'ENSG00000088832', 'approvedSymbol': 'FKBP1A', 'approvedName': 'FKBP prolyl isomerase 1A', 'mesh_heading': 'Oligodendroglioma', 'efo_term': 'anaplasti... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.574 | Q6 | What genes does Prednisone target when it's used to treat type III hypersensitivity reaction disease? | When used to treat type III hypersensitivity reaction disease, the drug Prednisone targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%prednisone%" OR LOWER(tradeNames_list) LIKE "%pre... | [{'UUID': 'DrugTargetsIndication121923_text_218714', 'drugName': 'Prednisone', 'tradeNames_list': "['Cortan', 'Cortancyl', 'Decortisyl', 'Delta-dome', 'Deltasone', 'FernisoneLiquid pred', 'Lodotra', 'Meticorten', 'Orasone', 'Paracort', 'Prednicen-mPrednisone', 'Prednisone intensol', 'Rayos', 'Servisone', 'Sterapred']",... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1177 | Q6 | What genes does Lenalidomide target when it's used to treat cancer? | Lenalidomide has not been approved by the FDA as a treatment for cancer, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are CRBN, DDB1, CUL4A, and RBX1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lenalidomide%" OR LOWER(tradeNames_list) LIKE "%l... | [{'UUID': 'DrugTargetsIndication121923_text_1111908', 'drugName': 'Lenalidomide', 'tradeNames_list': "['Revlimid']", 'syns_list': "['CC-5013', 'CDC-501', 'Lenalidomide', 'NSC-747972', 'SYP-1512']", 'target': 'ENSG00000113851', 'approvedSymbol': 'CRBN', 'approvedName': 'cereblon', 'mesh_heading': 'Prostatic Neoplasms, C... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1184 | Q6 | What genes does Naproxen target when it's used to treat pain? | When used to treat pain, the drug Naproxen targets the genes PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%naproxen%" OR LOWER(tradeNames_list) LIKE "%napro... | [{'UUID': 'DrugTargetsIndication121923_text_838302', 'drugName': 'Naproxen Sodium', 'tradeNames_list': "['Aleve', 'Anaprox', 'Anaprox ds', 'Naprelan', 'Naproxen sodium', 'Synflex']", 'syns_list': "['BAY-117031', 'BAY117031', 'BAYH6689', 'Naproxen sodiumNaproxen sodium anhydrous', 'Naproxen sodium salt', 'RS-3650']", 't... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.897 | Q6 | What genes does Doxepin Hydrochloride target when it's used to treat alcohol dependence? | When used to treat alcohol dependence, the drug Doxepin Hydrochloride targets the gene SLC6A2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%doxepin hydrochloride%" OR LOWER(tradeNames_list)... | [{'UUID': 'DrugTargetsIndication121923_text_440818', 'drugName': 'Doxepin Hydrochloride', 'tradeNames_list': "['Adapin', 'Doxepin hydrochloride', 'Quitaxon', 'Silenor', 'Sinequan', 'XepinZonalon']", 'syns_list': "['Doxepin hcl', 'Doxepin hydrochloride', 'NSC-108160', 'P-3693A']", 'target': 'ENSG00000103546', 'approvedS... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.956 | Q6 | What genes does Everolimus target when it's used to treat renal cell carcinoma? | When used to treat renal cell carcinoma, the drug Everolimus targets the gene FKBP1A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%everolimus%" OR LOWER(tradeNames_list) LIKE "%eve... | [{'UUID': 'DrugTargetsIndication121923_text_1085634', 'drugName': 'Everolimus', 'tradeNames_list': "['Afinitor', 'Afinitor disperz', 'Certican', 'Votubia', 'Zortress']", 'syns_list': "['40-o-(2-hydroxyethyl)-rapamycin', 'Everolimus', 'RAD 666', 'RAD-001RAD-666', 'RAD001', 'SDZ-RAD', 'Sdz rad']", 'target': 'ENSG00000088... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1057 | Q6 | What genes does Topiramate target when it's used to treat alcohol drinking? | Topiramate has not been approved by the FDA as a treatment for alcohol drinking, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, SCN10A, CA2, CA4, GABRA1, GABRB2, GABRG2, GABRB3, GABRA4, GABRG3, ... | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%topiramate%" OR LOWER(tradeNames_list) LIKE "%top... | [{'UUID': 'DrugTargetsIndication121923_text_457430', 'drugName': 'Topiramate', 'tradeNames_list': "['Epitomax', 'Eprontia', 'Qudexy xr', 'Topamax', 'Topamax sprinkleTopiramate', 'Trokendi xr']", 'syns_list': "['(-)-topiramate', 'Epitoma', 'Eprontia', 'MCN-4853', 'Qudexy', 'RWJ-17021RWJ-17021-000', 'Sincronil', 'Topamac... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1354 | Q6 | What genes does Travoprost target when it's used to treat glaucoma? | When used to treat glaucoma, the drug Travoprost targets the gene PTGFR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%travoprost%" OR LOWER(tradeNames_list) LIKE "%tra... | [{'UUID': 'DrugTargetsIndication121923_text_1149415', 'drugName': 'Travoprost', 'tradeNames_list': "['Izba', 'Travatan', 'Travatan z', 'Travoprost']", 'syns_list': "['AL-6221', 'NSC-760366', 'Otx-tp', 'Travoprost']", 'target': 'ENSG00000122420', 'approvedSymbol': 'PTGFR', 'approvedName': 'prostaglandin F receptor', 'me... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1373 | Q6 | What genes does Apixaban target when it's used to treat thrombotic disease? | When used to treat thrombotic disease, the drug Apixaban targets the gene F10. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%apixaban%" OR LOWER(tradeNames_list) LIKE "%apixa... | [{'UUID': 'DrugTargetsIndication121923_text_710510', 'drugName': 'Apixaban', 'tradeNames_list': "['Eliquis']", 'syns_list': "['Apixaban', 'BMS-562247', 'BMS-562247-01']", 'target': 'ENSG00000126218', 'approvedSymbol': 'F10', 'approvedName': 'coagulation factor X', 'mesh_heading': 'Thrombosis', 'efo_term': 'thrombotic d... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1448 | Q6 | What genes does Nitric Oxide target when it's used to treat varicose ulcer? | Nitric Oxide has not been approved by the FDA as a treatment for varicose ulcer, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are GUCY1B1, GUCY1B2, GUCY1A2, and GUCY1A1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%nitric oxide%" OR LOWER(tradeNames_list) LIKE "%n... | [{'UUID': 'DrugTargetsIndication121923_text_974398', 'drugName': 'Nitric Oxide', 'tradeNames_list': "['Genosyl', 'Inomax']", 'syns_list': "['Amidogen, oxo-', 'Inovent', 'Nitric oxide', 'Nitric oxide trimerNitrogen oxide (no)', 'Nitrosyl radical', 'OHM-11771']", 'target': 'ENSG00000061918', 'approvedSymbol': 'GUCY1B1', ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.891 | Q6 | What genes does Abemaciclib target when it's used to treat oligodendroglioma? | Abemaciclib has not been approved by the FDA as a treatment for oligodendroglioma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are CDK4 and CDK6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%abemaciclib%" OR LOWER(tradeNames_list) LIKE "%ab... | [{'UUID': 'DrugTargetsIndication121923_text_849328', 'drugName': 'Abemaciclib', 'tradeNames_list': "['Verzenio', 'Verzenios']", 'syns_list': "['Abemaciclib', 'LY-2835219', 'LY2835219', 'Ly-2835219']", 'target': 'ENSG00000135446', 'approvedSymbol': 'CDK4', 'approvedName': 'cyclin dependent kinase 4', 'mesh_heading': 'Ol... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1673 | Q6 | What genes does Amphetamine target when it's used to treat cocaine dependence? | Amphetamine has not been approved by the FDA as a treatment for cocaine dependence, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are SLC6A2 and SLC6A3. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%amphetamine%" OR LOWER(tradeNames_list) LIKE "%am... | [{'UUID': 'DrugTargetsIndication121923_text_418781', 'drugName': 'Dextroamphetamine', 'tradeNames_list': "['Dexedrine', 'Dextrostat', 'Xelstrym']", 'syns_list': "['Amfetamine, (s)-', 'Amphetamine, d-', 'D-amphetamine', 'DexamfetamineDexampex', 'Dexamphetamine', 'Dexedrine', 'Dexidrine', 'DextroamphetamineDextroamphetam... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.857 | Q6 | What genes does Isotretinoin target when it's used to treat ganglioneuroblastoma? | Isotretinoin has not been approved by the FDA as a treatment for ganglioneuroblastoma, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are RARG, RARB, and RARA. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%isotretinoin%" OR LOWER(tradeNames_list) LIKE "%i... | [{'UUID': 'DrugTargetsIndication121923_text_1053991', 'drugName': 'Isotretinoin', 'tradeNames_list': "['Absorica', 'Absorica ld', 'Accutane', 'Amnesteem', 'Claravis', 'IsotrexMyorisan', 'Roaccutane', 'Sotret', 'Zenatane']", 'syns_list': "['13 Cis-Retinoic Acid', '13-cis-retinoic acid', 'Isotretinoin', 'NSC-758156PAT-00... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.741 | Q6 | What genes does Zoledronic Acid target when it's used to treat multiple myeloma? | When used to treat multiple myeloma, the drug Zoledronic Acid targets the gene FDPS. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%zoledronic acid%" OR LOWER(tradeNames_list) LIKE ... | [{'UUID': 'DrugTargetsIndication121923_text_1099875', 'drugName': 'Zoledronic Acid', 'tradeNames_list': "['Aclasta', 'Reclast', 'Zerlinda', 'Zoledronic acid', 'Zometa']", 'syns_list': "['AK-156', 'Anhydrous zoledronic acid', 'CGP 42446', 'CGP-42446', 'CGP-42446ANSC-721517', 'Zoladrona acid mylan', 'Zoledronate', 'Zoled... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.724 | Q6 | What genes does Indomethacin target when it's used to treat Fish-eye disease? | Indomethacin has not been approved by the FDA as a treatment for Fish-eye disease, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%indomethacin%" OR LOWER(tradeNames_list) LIKE "%i... | [{'UUID': 'DrugTargetsIndication121923_text_828349', 'drugName': 'Indomethacin', 'tradeNames_list': "['Artracin', 'Artracin sr', 'Berlind 75 ret', 'Flexin-25 continusFlexin-50 continus', 'Flexin-75 continus', 'Imbrilon', 'Indo-lemmonIndo-paed', 'Indocid ret', 'Indocid-r', 'Indocin', 'Indocin sr', 'IndodermIndoflex', 'I... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.460 | Q6 | What genes does Lorlatinib target when it's used to treat lymphoma? | When used to treat lymphoma, the drug Lorlatinib targets the genes ALK and EML4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lorlatinib%" OR LOWER(tradeNames_list) LIKE "%lor... | [{'UUID': 'DrugTargetsIndication121923_text_991125', 'drugName': 'Lorlatinib', 'tradeNames_list': "['Lorbrena']", 'syns_list': "['Lorlatinib', 'PF-06463922']", 'target': 'ENSG00000171094', 'approvedSymbol': 'ALK', 'approvedName': 'ALK receptor tyrosine kinase', 'mesh_heading': 'Lymphoma', 'efo_term': 'lymphoma', 'yearO... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.267 | Q6 | What genes does Zanubrutinib target when it's used to treat neoplasm? | When used to treat neoplasm, the drug Zanubrutinib targets the gene BTK. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%zanubrutinib%" OR LOWER(tradeNames_list) LIKE "%z... | [{'UUID': 'DrugTargetsIndication121923_text_1025140', 'drugName': 'Zanubrutinib', 'tradeNames_list': "['Brukinsa']", 'syns_list': "['BGB-3111', 'Bgb-3111', 'Zanubrutinib']", 'target': 'ENSG00000010671', 'approvedSymbol': 'BTK', 'approvedName': 'Bruton tyrosine kinase', 'mesh_heading': 'Neoplasms', 'efo_term': 'neoplasm... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.78 | Q6 | What genes does Aspirin target when it's used to treat stroke? | When used to treat stroke, the drug Aspirin targets the genes PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%aspirin%" OR LOWER(tradeNames_list) LIKE "%aspiri... | [{'UUID': 'DrugTargetsIndication121923_text_833961', 'drugName': 'Aspirin', 'tradeNames_list': "['8-hour bayer', 'Acetosalic Acid', 'Acetylsalic acidAcetylsalicylic Acid', 'Alka rapid', 'Anadin all night', 'Angettes 75Aspirin', 'Aspro clr', 'Bayer extra strength aspirin for migraine painDanamep', 'Disprin cv', 'Disprin... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1785 | Q6 | What genes does Simvastatin target when it's used to treat carotid atherosclerosis? | Simvastatin has not been approved by the FDA as a treatment for carotid atherosclerosis, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is HMGCR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%simvastatin%" OR LOWER(tradeNames_list) LIKE "%si... | [{'UUID': 'DrugTargetsIndication121923_text_1103842', 'drugName': 'Simvastatin', 'tradeNames_list': "['Flolipid', 'Lacersa', 'Ranzolont', 'Simvador', 'Simvastatin', 'ZocorZocor heart-pro']", 'syns_list': "['C10AA01', 'MK-0733', 'MK-733', 'NSC-758706', 'SimvastatinSimvastatin hydroxy acid', 'Synvinolin']", 'target': 'EN... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.450 | Q6 | What genes does Indomethacin target when it's used to treat pain? | When used to treat pain, the drug Indomethacin targets the genes PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%indomethacin%" OR LOWER(tradeNames_list) LIKE "%i... | [{'UUID': 'DrugTargetsIndication121923_text_828372', 'drugName': 'Indomethacin', 'tradeNames_list': "['Artracin', 'Artracin sr', 'Berlind 75 ret', 'Flexin-25 continusFlexin-50 continus', 'Flexin-75 continus', 'Imbrilon', 'Indo-lemmonIndo-paed', 'Indocid ret', 'Indocid-r', 'Indocin', 'Indocin sr', 'IndodermIndoflex', 'I... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.401 | Q6 | What genes does Palonosetron Hydrochloride target when it's used to treat cancer? | When used to treat cancer, the drug Palonosetron Hydrochloride targets the gene HTR3A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%palonosetron hydrochloride%" OR LOWER(tradeNames_... | [{'UUID': 'DrugTargetsIndication121923_text_205522', 'drugName': 'Palonosetron Hydrochloride', 'tradeNames_list': "['Aloxi', 'Palonosetron hydrochloride']", 'syns_list': "['Palonocetron hydrochloride', 'Palonosetron (as hydrochloride)Palonosetron hcl', 'Palonosetron hydrochloride', 'RS-25259-197']", 'target': 'ENSG0000... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.179 | Q6 | What genes does Vardenafil Hydrochloride target when it's used to treat erectile dysfunction? | When used to treat erectile dysfunction, the drug Vardenafil Hydrochloride targets the gene PDE5A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%vardenafil hydrochloride%" OR LOWER(tradeNames_li... | [{'UUID': 'DrugTargetsIndication121923_text_1094112', 'drugName': 'Vardenafil Hydrochloride', 'tradeNames_list': "['Levitra', 'Staxyn', 'Vardenafil hydrochloride']", 'syns_list': "['BAY 38-9456', 'BAY-38-9456', 'Nuviva', 'Vardenafil hclVardenafil hydrochloride', 'Vardenafil hydrochloride anhydrousVardenafil hydrochlori... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1051 | Q6 | What genes does Cenobamate target when it's used to treat Seizure? | When used to treat Seizure, the drug Cenobamate targets the genes SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, SCN10A, GABRA1, GABRB2, GABRG2, GABRB3, GABRA4, GABRG3, GABRQ, GABRA3, GABRP, GABRD, GABRG1, GABRB1, GABRE, GABRA2, GABRA5, and GABRA6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%cenobamate%" OR LOWER(tradeNames_list) LIKE "%cen... | [{'UUID': 'DrugTargetsIndication121923_text_456010', 'drugName': 'Cenobamate', 'tradeNames_list': "['Xcopri']", 'syns_list': "['Cenobamate', 'YKP-3089', 'YKP3089']", 'target': 'ENSG00000144285', 'approvedSymbol': 'SCN1A', 'approvedName': 'sodium voltage-gated channel alpha subunit 1', 'mesh_heading': 'Seizures', 'efo_t... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1737 | Q6 | What genes does Celecoxib target when it's used to treat myeloproliferative disorder? | Celecoxib has not been approved by the FDA as a treatment for myeloproliferative disorder, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is PTGS2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%celecoxib%" OR LOWER(tradeNames_list) LIKE "%cele... | [{'UUID': 'DrugTargetsIndication121923_text_833404', 'drugName': 'Celecoxib', 'tradeNames_list': "['Celebra', 'Celebrex', 'Celecoxib', 'Elyxyb', 'Onsenal']", 'syns_list': "['Celecoxib', 'DFN-15', 'DFN15', 'NSC-719627', 'NSC-758624', 'SC-58635']", 'target': 'ENSG00000073756', 'approvedSymbol': 'PTGS2', 'approvedName': '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1609 | Q6 | What genes does Topotecan Hydrochloride target when it's used to treat small cell lung carcinoma? | When used to treat small cell lung carcinoma, the drug Topotecan Hydrochloride targets the gene TOP1MT. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%topotecan hydrochloride%" OR LOWER(tradeNames_lis... | [{'UUID': 'DrugTargetsIndication121923_text_1193645', 'drugName': 'Topotecan Hydrochloride', 'tradeNames_list': "['Hycamptin', 'Hycamtin', 'Topotecan', 'Topotecan hydrochloride']", 'syns_list': "['Evotopin', 'NSC-759263', 'Nogitecan hydrochloride', 'SK&F S-104864-ASK&F-S-104864A', 'SK-S-104864-A', 'Topotecan (as hydroc... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1869 | Q6 | What genes does Niraparib target when it's used to treat ovarian neoplasm? | Niraparib has not been approved by the FDA as a treatment for ovarian neoplasm, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are PARP2 and PARP1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%niraparib%" OR LOWER(tradeNames_list) LIKE "%nira... | [{'UUID': 'DrugTargetsIndication121923_text_823346', 'drugName': 'Niraparib Tosylate', 'tradeNames_list': "['Zejula']", 'syns_list': "['MK-4827-TOSYLATE', 'Niraparib tosylate', 'Niraparib tosylate anhydrousNiraparib tosylate monohydrate']", 'target': 'ENSG00000129484', 'approvedSymbol': 'PARP2', 'approvedName': 'poly(A... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.602 | Q6 | What genes does Ondansetron target when it's used to treat Nausea and vomiting? | When used to treat Nausea and vomiting, the drug Ondansetron targets the gene HTR3A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ondansetron%" OR LOWER(tradeNames_list) LIKE "%on... | [{'UUID': 'DrugTargetsIndication121923_text_205897', 'drugName': 'Ondansetron', 'tradeNames_list': "['Ondansetron', 'Zofran', 'Zofran odt', 'Zuplenz']", 'syns_list': "['A04AA01', 'Desmethylondansetron', 'EUR-1025', 'GR-38032', 'GR-38032FNSC-757870', 'Ondansetron', 'Zofran']", 'target': 'ENSG00000166736', 'approvedSymbo... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.63 | Q6 | What genes does Methylphenidate target when it's used to treat nicotine dependence? | Methylphenidate has not been approved by the FDA as a treatment for nicotine dependence, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are SLC6A2 and SLC6A3. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%methylphenidate%" OR LOWER(tradeNames_list) LIKE ... | [{'UUID': 'DrugTargetsIndication121923_text_435218', 'drugName': 'Methylphenidate Hydrochloride', 'tradeNames_list': "['Adhansia xr', 'Aptensio xr', 'Concerta', 'Delmosart', 'Equasym', 'Equasym xlJornay pm', 'Matoride xl', 'Medikinet', 'Medikinet xl', 'Metadate cdMetadate er', 'Methylin', 'Methylin er', 'Methylphenidat... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1309 | Q6 | What genes does Empagliflozin target when it's used to treat type 2 diabetes mellitus? | When used to treat type 2 diabetes mellitus, the drug Empagliflozin targets the gene SLC5A2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%empagliflozin%" OR LOWER(tradeNames_list) LIKE "%... | [{'UUID': 'DrugTargetsIndication121923_text_1096521', 'drugName': 'Empagliflozin', 'tradeNames_list': "['Bi 10773', 'Jardiance']", 'syns_list': "['BI 10773', 'BI-10773', 'Bi10773', 'Empagliflozin']", 'target': 'ENSG00000140675', 'approvedSymbol': 'SLC5A2', 'approvedName': 'solute carrier family 5 member 2', 'mesh_headi... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.879 | Q6 | What genes does Ibuprofen target when it's used to treat vaginal inflammation? | When used to treat vaginal inflammation, the drug Ibuprofen targets the genes PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ibuprofen%" OR LOWER(tradeNames_list) LIKE "%ibup... | [{'UUID': 'DrugTargetsIndication121923_text_840167', 'drugName': 'Ibuprofen', 'tradeNames_list': '[\'Aches-n-pain\', \'Advil\', \'Advil liqui-gels\', \'Advil migraine liqui-gelsAnadin joint pain\', \'Anadin liquifast\', \'Anadin period pain reliefAnadin ultra\', \'Apsifen\', \'Apsifen-f\', \'Arthrofen 200\', \'Arthrofe... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1491 | Q6 | What genes does Belzutifan target when it's used to treat renal cell carcinoma? | When used to treat renal cell carcinoma, the drug Belzutifan targets the gene EPAS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%belzutifan%" OR LOWER(tradeNames_list) LIKE "%bel... | [{'UUID': 'DrugTargetsIndication121923_text_1192112', 'drugName': 'Belzutifan', 'tradeNames_list': "['Welireg']", 'syns_list': "['Belzutifan', 'MK-6482', 'MK6482', 'Mk-6482', 'PT-2977', 'PT2977', 'Pt 2977Pt2977']", 'target': 'ENSG00000116016', 'approvedSymbol': 'EPAS1', 'approvedName': 'endothelial PAS domain protein 1... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1880 | Q6 | What genes does Zoledronic Acid target when it's used to treat postmenopausal osteoporosis? | When used to treat postmenopausal osteoporosis, the drug Zoledronic Acid targets the gene FDPS. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%zoledronic acid%" OR LOWER(tradeNames_list) LIKE ... | [{'UUID': 'DrugTargetsIndication121923_text_1099877', 'drugName': 'Zoledronic Acid', 'tradeNames_list': "['Aclasta', 'Reclast', 'Zerlinda', 'Zoledronic acid', 'Zometa']", 'syns_list': "['AK-156', 'Anhydrous zoledronic acid', 'CGP 42446', 'CGP-42446', 'CGP-42446ANSC-721517', 'Zoladrona acid mylan', 'Zoledronate', 'Zoled... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.282 | Q6 | What genes does Epinephrine target when it's used to treat allergic rhinitis? | When used to treat allergic rhinitis, the drug Epinephrine targets the genes ADRA1A, ADRB2, ADRB1, ADRB3, ADRA1D, ADRA1B, ADRA2A, ADRA2C, and ADRA2B. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%epinephrine%" OR LOWER(tradeNames_list) LIKE "%ep... | [{'UUID': 'DrugTargetsIndication121923_text_360935', 'drugName': 'Epinephrine', 'tradeNames_list': "['Adren co', 'Adrenaclick', 'Adrenalin', 'Ana-Kit', 'Ana-guard', 'AnapenAnaphylactic shock drug kit', 'Asma-vydrin', 'Asthmahaler', 'Auvi-qBronkaid mist', 'Brovon', 'Emerade', 'Epi e z pen jr', 'EpinephrineEpinephrine (c... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.37 | Q6 | What genes does Sitagliptin target when it's used to treat hepatitis C virus infection? | Sitagliptin has not been approved by the FDA as a treatment for hepatitis C virus infection, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is DPP4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%sitagliptin%" OR LOWER(tradeNames_list) LIKE "%si... | [{'UUID': 'DrugTargetsIndication121923_text_933414', 'drugName': 'Sitagliptin', 'tradeNames_list': "['Januvia']", 'syns_list': "['LEZ-763', 'LEZ763', 'MK-0431', 'Sitagliptin']", 'target': 'ENSG00000197635', 'approvedSymbol': 'DPP4', 'approvedName': 'dipeptidyl peptidase 4', 'mesh_heading': 'Hepatitis C', 'efo_term': 'h... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1517 | Q6 | What genes does Halobetasol Propionate target when it's used to treat psoriasis? | When used to treat psoriasis, the drug Halobetasol Propionate targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%halobetasol propionate%" OR LOWER(tradeNames_list... | [{'UUID': 'DrugTargetsIndication121923_text_240729', 'drugName': 'Halobetasol Propionate', 'tradeNames_list': "['Bryhali', 'Halobetasol propionate', 'Lexette', 'Ultravate']", 'syns_list': "['21-chloro diflorasone', 'BMY-30056', 'CGP-14,458', 'CGP-14458Halobetasol', 'Halobetasol propionate', 'IDP-122', 'Jemdel', 'Ulobet... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.669 | Q6 | What genes does Oxycodone target when it's used to treat pain? | When used to treat pain, the drug Oxycodone targets the gene OPRM1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%oxycodone%" OR LOWER(tradeNames_list) LIKE "%oxyc... | [{'UUID': 'DrugTargetsIndication121923_text_766861', 'drugName': 'Oxycodone Hydrochloride', 'tradeNames_list': "['Abtard', 'Candox', 'Carexil', 'Dolocodon pr', 'Leveraxo', 'Longtec', 'LynlorOxaydo', 'Oxecta', 'Oxeltra', 'Oxycodone hydrochloride', 'OxycontinOxylan', 'Oxynorm', 'Reltebon', 'Roxicodone', 'Roxybond', 'Shor... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1829 | Q6 | What genes does Amantadine Hydrochloride target when it's used to treat influenza? | When used to treat influenza, the drug Amantadine Hydrochloride targets the genes GRIN1, GRIN2A, GRIN2B, GRIN2D, GRIN3B, GRIN2C, and GRIN3A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%amantadine hydrochloride%" OR LOWER(tradeNames_li... | [{'UUID': 'DrugTargetsIndication121923_text_441090', 'drugName': 'Amantadine Hydrochloride', 'tradeNames_list': "['Amantadine hydrochloride', 'Gocovri', 'Lysovir', 'Mantadine', 'Osmolex erSymadine', 'Symmetrel']", 'syns_list': "['Adamantanamine hydrochloride', 'Amantadine hclAmantadine hydrochloride', 'EXP-105-1', 'Man... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1446 | Q6 | What genes does Montelukast target when it's used to treat allergic rhinitis? | When used to treat allergic rhinitis, the drug Montelukast targets the gene CYSLTR1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%montelukast%" OR LOWER(tradeNames_list) LIKE "%mo... | [{'UUID': 'DrugTargetsIndication121923_text_1100425', 'drugName': 'Montelukast', 'tradeNames_list': "['Singulair']", 'syns_list': "['Brondilat', 'MK-476', 'Montelukast']", 'target': 'ENSG00000173198', 'approvedSymbol': 'CYSLTR1', 'approvedName': 'cysteinyl leukotriene receptor 1', 'mesh_heading': 'Rhinitis, Allergic', ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.986 | Q6 | What genes does Dextroamphetamine target when it's used to treat narcolepsy-cataplexy syndrome? | When used to treat narcolepsy-cataplexy syndrome, the drug Dextroamphetamine targets the genes SLC6A2, SLC18A2, and SLC6A3. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%dextroamphetamine%" OR LOWER(tradeNames_list) LIK... | [{'UUID': 'DrugTargetsIndication121923_text_418427', 'drugName': 'Dextroamphetamine', 'tradeNames_list': "['Dexedrine', 'Dextrostat', 'Xelstrym']", 'syns_list': "['Amfetamine, (s)-', 'Amphetamine, d-', 'D-amphetamine', 'DexamfetamineDexampex', 'Dexamphetamine', 'Dexedrine', 'Dexidrine', 'DextroamphetamineDextroamphetam... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1572 | Q6 | What genes does Alectinib target when it's used to treat central nervous system cancer? | Alectinib has not been approved by the FDA as a treatment for central nervous system cancer, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are RET, ALK, and EML4. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%alectinib%" OR LOWER(tradeNames_list) LIKE "%alec... | [{'UUID': 'DrugTargetsIndication121923_text_945672', 'drugName': 'Alectinib', 'tradeNames_list': "['Alecensa']", 'syns_list': "['AF-802', 'AF802', 'Alectinib', 'CH-5424802', 'CH5424802', 'RO-5424802RO5424802']", 'target': 'ENSG00000171094', 'approvedSymbol': 'ALK', 'approvedName': 'ALK receptor tyrosine kinase', 'mesh_... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.745 | Q6 | What genes does Azilsartan Medoxomil target when it's used to treat cardiovascular disease? | When used to treat cardiovascular disease, the drug Azilsartan Medoxomil targets the gene AGTR1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%azilsartan medoxomil%" OR LOWER(tradeNames_list) ... | [{'UUID': 'DrugTargetsIndication121923_text_1072694', 'drugName': 'Azilsartan Medoxomil', 'tradeNames_list': "['Edarbi']", 'syns_list': "['AR-14', 'Azilsartan medoxomil', 'Ipreziv', 'TAK 491', 'TAK-491']", 'target': 'ENSG00000144891', 'approvedSymbol': 'AGTR1', 'approvedName': 'angiotensin II receptor type 1', 'mesh_he... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.194 | Q6 | What genes does Fluticasone Propionate target when it's used to treat Airway obstruction? | When used to treat Airway obstruction, the drug Fluticasone Propionate targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fluticasone propionate%" OR LOWER(tradeNames_list... | [{'UUID': 'DrugTargetsIndication121923_text_232526', 'drugName': 'Fluticasone Propionate', 'tradeNames_list': "['Aerivio spiromax', 'Airflusal forspiro', 'Armonair digihalerArmonair respiclick', 'Cutivate', 'Flixonase', 'Flixotide', 'FlonaseFlonase allergy relief', 'Flovent', 'Flovent diskus 100Flovent diskus 250', 'Fl... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.927 | Q6 | What genes does Levothyroxine Sodium target when it's used to treat thyroid cancer? | When used to treat thyroid cancer, the drug Levothyroxine Sodium targets the genes THRA and THRB. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%levothyroxine sodium%" OR LOWER(tradeNames_list) ... | [{'UUID': 'DrugTargetsIndication121923_text_924836', 'drugName': 'Levothyroxine Sodium', 'tradeNames_list': "['Eltroxin', 'Ermeza', 'Euthyrox', 'Evotrox', 'L-thyroxine henning', 'Levo-tLevolet', 'Levothroid', 'Levothyroid', 'Levothyroxine sodium', 'LevoxineLevoxyl', 'Novothyrox', 'Soloxine', 'Synthroid', 'Thyquidity', ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.462 | Q6 | What genes does Estradiol target when it's used to treat hypogonadism? | When used to treat hypogonadism, the drug Estradiol targets the gene ESR1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%estradiol%" OR LOWER(tradeNames_list) LIKE "%estr... | [{'UUID': 'DrugTargetsIndication121923_text_824180', 'drugName': 'Estradiol', 'tradeNames_list': "['Adgyn estro', 'Alora', 'Aquagen', 'Bedol', 'Climara', 'Climara ProDermestril 100', 'Dermestril 25', 'Dermestril 50', 'Dermestril septem 25Dermestril septem 50', 'Dermestril septem 75', 'Divigel', 'E-CypionateElestrim', '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.682 | Q6 | What genes does Duvelisib target when it's used to treat neoplasm? | When used to treat neoplasm, the drug Duvelisib targets the genes PIK3CD and PIK3CG. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%duvelisib%" OR LOWER(tradeNames_list) LIKE "%duve... | [{'UUID': 'DrugTargetsIndication121923_text_858759', 'drugName': 'Duvelisib', 'tradeNames_list': "['Copiktra']", 'syns_list': "['Duvelisib', 'Duvelisib hydrate', 'Duvelisib monohydrate', 'INK-1147INK-1197', 'IPI-145']", 'target': 'ENSG00000171608', 'approvedSymbol': 'PIK3CD', 'approvedName': 'phosphatidylinositol-4,5-b... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.767 | Q6 | What genes does Lorazepam target when it's used to treat alcohol dependence? | Lorazepam has not been approved by the FDA as a treatment for alcohol dependence, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are GABRA1, GABRB2, GABRG2, GABRB3, GABRA4, GABRG3, GABRQ, GABRA3, GABRP, GABRD, GABRG1, GABRB1, GABRE, GABRA2, GABRA5, and GABRA6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lorazepam%" OR LOWER(tradeNames_list) LIKE "%lora... | [{'UUID': 'DrugTargetsIndication121923_text_958594', 'drugName': 'Lorazepam', 'tradeNames_list': "['Abbloraz', 'Ativan', 'Loraz', 'Lorazepam', 'Lorazepam intensolLorazepam preservative free', 'Loreev xr', 'Temesta']", 'syns_list': "['Lorazepam', 'Lorazepam civ', 'NSC-289758', 'WY-4036']", 'target': 'ENSG00000145864', '... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1809 | Q6 | What genes does Lidocaine target when it's used to treat Ventricular arrhythmia? | When used to treat Ventricular arrhythmia, the drug Lidocaine targets the genes SCN1A, SCN5A, SCN4A, SCN7A, SCN2A, SCN9A, SCN3A, SCN11A, SCN8A, and SCN10A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%lidocaine%" OR LOWER(tradeNames_list) LIKE "%lido... | [{'UUID': 'DrugTargetsIndication121923_text_638354', 'drugName': 'Lidocaine', 'tradeNames_list': "['Alphacaine', 'Anestacon', 'Dentipatch', 'Lidocaine', 'LidodermLignocaine Hcl', 'Lignostab', 'Lmx 4', 'Oraqix', 'Vagisil', 'XylocaineXylodase', 'Xylotox', 'Ztlido']", 'syns_list': "['ALGRX 3268', 'ALGRX-3268', 'Anestacon'... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1603 | Q6 | What genes does Isotretinoin target when it's used to treat epidermolysis bullosa? | Isotretinoin has not been approved by the FDA as a treatment for epidermolysis bullosa, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are RARG, RARB, and RARA. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%isotretinoin%" OR LOWER(tradeNames_list) LIKE "%i... | [{'UUID': 'DrugTargetsIndication121923_text_1053981', 'drugName': 'Isotretinoin', 'tradeNames_list': "['Absorica', 'Absorica ld', 'Accutane', 'Amnesteem', 'Claravis', 'IsotrexMyorisan', 'Roaccutane', 'Sotret', 'Zenatane']", 'syns_list': "['13 Cis-Retinoic Acid', '13-cis-retinoic acid', 'Isotretinoin', 'NSC-758156PAT-00... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.735 | Q6 | What genes does Niraparib target when it's used to treat neoplasm? | When used to treat neoplasm, the drug Niraparib targets the genes PARP2 and PARP1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%niraparib%" OR LOWER(tradeNames_list) LIKE "%nira... | [{'UUID': 'DrugTargetsIndication121923_text_823338', 'drugName': 'Niraparib Tosylate', 'tradeNames_list': "['Zejula']", 'syns_list': "['MK-4827-TOSYLATE', 'Niraparib tosylate', 'Niraparib tosylate anhydrousNiraparib tosylate monohydrate']", 'target': 'ENSG00000129484', 'approvedSymbol': 'PARP2', 'approvedName': 'poly(A... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.418 | Q6 | What genes does Belinostat target when it's used to treat mature T-cell and NK-cell non-Hodgkin lymphoma? | When used to treat mature T-cell and NK-cell non-Hodgkin lymphoma, the drug Belinostat targets the genes HDAC1, HDAC3, HDAC6, HDAC2, HDAC5, HDAC7, HDAC8, HDAC11, HDAC4, HDAC9, and HDAC10. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%belinostat%" OR LOWER(tradeNames_list) LIKE "%bel... | [{'UUID': 'DrugTargetsIndication121923_text_1079996', 'drugName': 'Belinostat', 'tradeNames_list': "['Beleodaq']", 'syns_list': "['Belinostat', 'NSC-726630', 'NSC726630', 'PX-105684', 'PXD-101', 'PXD101']", 'target': 'ENSG00000094631', 'approvedSymbol': 'HDAC6', 'approvedName': 'histone deacetylase 6', 'mesh_heading': ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1107 | Q6 | What genes does Enzalutamide target when it's used to treat metastatic prostate cancer? | When used to treat metastatic prostate cancer, the drug Enzalutamide targets the gene AR. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%enzalutamide%" OR LOWER(tradeNames_list) LIKE "%e... | [{'UUID': 'DrugTargetsIndication121923_text_921123', 'drugName': 'Enzalutamide', 'tradeNames_list': "['Xtandi']", 'syns_list': "['Enzalutamide', 'MDV-3100', 'MDV3100', 'Mdv 3100']", 'target': 'ENSG00000169083', 'approvedSymbol': 'AR', 'approvedName': 'androgen receptor', 'mesh_heading': 'Prostatic Neoplasms', 'efo_term... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.832 | Q6 | What genes does Brimonidine Tartrate target when it's used to treat open-angle glaucoma? | When used to treat open-angle glaucoma, the drug Brimonidine Tartrate targets the genes ADRA2A, ADRA2C, and ADRA2B. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%brimonidine tartrate%" OR LOWER(tradeNames_list) ... | [{'UUID': 'DrugTargetsIndication121923_text_1034128', 'drugName': 'Brimonidine Tartrate', 'tradeNames_list': "['Alphagan', 'Alphagan p', 'Brimonidine tartrate', 'Brymont', 'LumifyMirvaso', 'Qoliana']", 'syns_list': "['AGN 190342-LF', 'AGN-190342-LF', 'AGN-190342LF', 'Brimonidine d-tartrateBrimonidine tartrate', 'Bromox... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1498 | Q6 | What genes does Tadalafil target when it's used to treat Duchenne muscular dystrophy? | Tadalafil has not been approved by the FDA as a treatment for Duchenne muscular dystrophy, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is PDE5A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%tadalafil%" OR LOWER(tradeNames_list) LIKE "%tada... | [{'UUID': 'DrugTargetsIndication121923_text_1094098', 'drugName': 'Tadalafil', 'tradeNames_list': "['Adcirca', 'Cialis', 'Tadliq']", 'syns_list': "['IC-351', 'IC351', 'LY-450190', 'LY450190', 'NSC-750236', 'NSC-759172Tadalafil', 'Tadalafil mylan', 'Trans-tadalafil']", 'target': 'ENSG00000138735', 'approvedSymbol': 'PDE... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.623 | Q6 | What genes does Amlodipine Benzoate target when it's used to treat diabetes mellitus? | When used to treat diabetes mellitus, the drug Amlodipine Benzoate targets the genes CACNA1C, CACNA1S, CACNA1D, and CACNA1F. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%amlodipine benzoate%" OR LOWER(tradeNames_list) L... | [{'UUID': 'DrugTargetsIndication121923_text_1044025', 'drugName': 'Amlodipine Benzoate', 'tradeNames_list': "['Katerzia']", 'syns_list': "['Amlodipine benzoate']", 'target': 'ENSG00000151067', 'approvedSymbol': 'CACNA1C', 'approvedName': 'calcium voltage-gated channel subunit alpha1 C', 'mesh_heading': 'Diabetes Mellit... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.117 | Q6 | What genes does Prednisolone Acetate target when it's used to treat Corneal scarring? | When used to treat Corneal scarring, the drug Prednisolone Acetate targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%prednisolone acetate%" OR LOWER(tradeNames_list) ... | [{'UUID': 'DrugTargetsIndication121923_text_243758', 'drugName': 'Prednisolone Acetate', 'tradeNames_list': "['Econopred', 'Flo-pred', 'Meticortelone', 'Omnipred', 'Pred forte', 'Pred ftePred mild', 'Prednisolone acetate', 'Sterane', 'Ultracortenol']", 'syns_list': "['NSC-10966', 'Prednisolone 21-acetate', 'Prednisolon... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.423 | Q6 | What genes does Vandetanib target when it's used to treat medullary thyroid gland carcinoma? | When used to treat medullary thyroid gland carcinoma, the drug Vandetanib targets the genes EGFR, ERBB3, KDR, SRC, TEK, ERBB2, FLT1, FLT4, EPHA2, RET, ERBB4, EPHB4, PTK6, EPHB2, EPHA5, EPHA4, EPHA8, EPHA6, EPHA7, EPHB3, EPHA3, EPHB1, EPHA1, EPHB6, and EPHA10. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%vandetanib%" OR LOWER(tradeNames_list) LIKE "%van... | [{'UUID': 'DrugTargetsIndication121923_text_210189', 'drugName': 'Vandetanib', 'tradeNames_list': "['Caprelsa', 'Zactima']", 'syns_list': "['GNF-PF-2188', 'NSC-744325', 'NSC-760766', 'Vandetanib', 'ZD-64', 'ZD-6474ZD6474']", 'target': 'ENSG00000146648', 'approvedSymbol': 'EGFR', 'approvedName': 'epidermal growth factor... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1911 | Q6 | What genes does Brimonidine Tartrate target when it's used to treat Erythema? | When used to treat Erythema, the drug Brimonidine Tartrate targets the genes ADRA2A, ADRA2C, and ADRA2B. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%brimonidine tartrate%" OR LOWER(tradeNames_list) ... | [{'UUID': 'DrugTargetsIndication121923_text_1034125', 'drugName': 'Brimonidine Tartrate', 'tradeNames_list': "['Alphagan', 'Alphagan p', 'Brimonidine tartrate', 'Brymont', 'LumifyMirvaso', 'Qoliana']", 'syns_list': "['AGN 190342-LF', 'AGN-190342-LF', 'AGN-190342LF', 'Brimonidine d-tartrateBrimonidine tartrate', 'Bromox... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.978 | Q6 | What genes does Vandetanib target when it's used to treat acute myeloid leukemia? | Vandetanib has not been approved by the FDA as a treatment for acute myeloid leukemia, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene targets are EGFR, ERBB3, KDR, SRC, TEK, ERBB2, FLT1, FLT4, EPHA2, RET, ERBB4, EPHB4, PTK6, EPHB2, EPHA5, EPHA4, EPHA8, EPHA6, EPHA7, EPH... | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%vandetanib%" OR LOWER(tradeNames_list) LIKE "%van... | [{'UUID': 'DrugTargetsIndication121923_text_210151', 'drugName': 'Vandetanib', 'tradeNames_list': "['Caprelsa', 'Zactima']", 'syns_list': "['GNF-PF-2188', 'NSC-744325', 'NSC-760766', 'Vandetanib', 'ZD-64', 'ZD-6474ZD6474']", 'target': 'ENSG00000146648', 'approvedSymbol': 'EGFR', 'approvedName': 'epidermal growth factor... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.611 | Q6 | What genes does Aripiprazole target when it's used to treat depressive disorder? | When used to treat depressive disorder, the drug Aripiprazole targets the genes DRD2, HTR2A, and HTR1A. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%aripiprazole%" OR LOWER(tradeNames_list) LIKE "%a... | [{'UUID': 'DrugTargetsIndication121923_text_158030', 'drugName': 'Aripiprazole Lauroxil', 'tradeNames_list': "['Aristada', 'Aristada initio kit']", 'syns_list': "['ALKS 9072', 'ALKS-9070', 'ALKS-9072', 'Aripiprazole lauroxilAristada initio', 'RDC-3317', 'RDC3317']", 'target': 'ENSG00000149295', 'approvedSymbol': 'DRD2'... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1919 | Q6 | What genes does Ketorolac Tromethamine target when it's used to treat cataract? | When used to treat cataract, the drug Ketorolac Tromethamine targets the genes PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%ketorolac tromethamine%" OR LOWER(tradeNames_list... | [{'UUID': 'DrugTargetsIndication121923_text_841850', 'drugName': 'Ketorolac Tromethamine', 'tradeNames_list': "['Acular', 'Acular ls', 'Acular preservative free', 'AcuvailKetorolac tromethamine', 'Sprix', 'Toradol']", 'syns_list': "['Dolac', 'Ketorolac trometamol', 'Ketorolac tromethamine', 'LixidolNSC-758637', 'Tarasy... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.92 | Q6 | What genes does Fluocinolone Acetonide target when it's used to treat retinopathy? | Fluocinolone Acetonide has not been approved by the FDA as a treatment for retinopathy, but it is currently undergoing evaluation in clinical trials for this purpose. The proposed gene target is NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%fluocinolone acetonide%" OR LOWER(tradeNames_list... | [{'UUID': 'DrugTargetsIndication121923_text_242229', 'drugName': 'Fluocinolone Acetonide', 'tradeNames_list': "['Capex', 'Derma-smoothe/fs', 'Dermotic', 'Fluocet', 'Fluocinolone acetonideFluonid', 'Fluotrex', 'Fs shampoo', 'Iluvien', 'Retisert', 'SynalarSynalar fte', 'Synalar-c', 'Synalar-hp', 'Synalar-n', 'Synandone',... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.855 | Q6 | What genes does Capmatinib Hydrochloride target when it's used to treat non-small cell lung carcinoma? | When used to treat non-small cell lung carcinoma, the drug Capmatinib Hydrochloride targets the gene MET. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%capmatinib hydrochloride%" OR LOWER(tradeNames_li... | [{'UUID': 'DrugTargetsIndication121923_text_936122', 'drugName': 'Capmatinib Hydrochloride', 'tradeNames_list': "['Tabrecta']", 'syns_list': "['Capmatinib hydrochloride', 'Capmatinib hydrochloride hydrateNVP-INC280-AAA']", 'target': 'ENSG00000105976', 'approvedSymbol': 'MET', 'approvedName': 'MET proto-oncogene, recept... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1521 | Q6 | What genes does Cabazitaxel target when it's used to treat prostate cancer? | When used to treat prostate cancer, the drug Cabazitaxel targets the genes TUBB4B, TUBB1, TUBA3C, TUBA4A, TUBB3, TUBA1A, TUBB4A, TUBB8, TUBB, TUBA1B, TUBA1C, TUBA3E, TUBB2A, TUBB2B, and TUBB6. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%cabazitaxel%" OR LOWER(tradeNames_list) LIKE "%ca... | [{'UUID': 'DrugTargetsIndication121923_text_67932', 'drugName': 'Cabazitaxel', 'tradeNames_list': "['Jevtana', 'Jevtana kit']", 'syns_list': "['Cabazitaxel', 'Cabazitaxel acetonate', 'Jevtana', 'NSC-761432', 'TXD 258TXD-258', 'XRP 6258', 'XRP-6258']", 'target': 'ENSG00000188229', 'approvedSymbol': 'TUBB4B', 'approvedNa... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1918 | Q6 | What genes does Nizatidine target when it's used to treat Peptic ulcer? | When used to treat Peptic ulcer, the drug Nizatidine targets the gene HRH2. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%nizatidine%" OR LOWER(tradeNames_list) LIKE "%niz... | [{'UUID': 'DrugTargetsIndication121923_text_1100308', 'drugName': 'Nizatidine', 'tradeNames_list': "['Axid', 'Axid ar', 'Nizatidine', 'Zinga 150', 'Zinga 300']", 'syns_list': "['Acinon', 'LY 139037', 'LY-139037', 'NSC-759289', 'Nizatidine']", 'target': 'ENSG00000113749', 'approvedSymbol': 'HRH2', 'approvedName': 'hista... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.760 | Q6 | What genes does Imiquimod target when it's used to treat skin basal cell carcinoma? | When used to treat skin basal cell carcinoma, the drug Imiquimod targets the gene TLR7. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%imiquimod%" OR LOWER(tradeNames_list) LIKE "%imiq... | [{'UUID': 'DrugTargetsIndication121923_text_919782', 'drugName': 'Imiquimod', 'tradeNames_list': "['Aldara', 'Imiquimod', 'Zyclara']", 'syns_list': "['Aldara', 'Imiquimod', 'NSC-369100', 'NSC-759651', 'R-837', 'S-26308', 'S26308Tmx-101']", 'target': 'ENSG00000196664', 'approvedSymbol': 'TLR7', 'approvedName': 'toll lik... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.504 | Q6 | What genes does Givosiran Sodium target when it's used to treat liver disease? | When used to treat liver disease, the drug Givosiran Sodium targets the gene ALAS1. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%givosiran sodium%" OR LOWER(tradeNames_list) LIKE... | [{'UUID': 'DrugTargetsIndication121923_text_1100369', 'drugName': 'Givosiran Sodium', 'tradeNames_list': "['Givlaari']", 'syns_list': "['Givosiran sodium']", 'target': 'ENSG00000023330', 'approvedSymbol': 'ALAS1', 'approvedName': "5'-aminolevulinate synthase 1", 'mesh_heading': 'Porphyrias, Hepatic', 'efo_term': 'liver... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
Q6.1287 | Q6 | What genes does Esomeprazole Magnesium target when it's used to treat osteoarthritis? | When used to treat osteoarthritis, the drug Esomeprazole Magnesium targets the genes ATP4A and ATP4B. | SELECT DISTINCT UUID, drugName, tradeNames_list, syns_list, target, approvedSymbol, approvedName, mesh_heading, efo_term, yearOfFirstApproval, max_phase_for_ind
FROM `{project_id}.{dataset_name}.DrugTargets_IndicationsAndTherapeuticUses`
WHERE (LOWER(drugName) LIKE "%esomeprazole magnesium%" OR LOWER(tradeNames_list... | [{'UUID': 'DrugTargetsIndication121923_text_1097877', 'drugName': 'Esomeprazole Magnesium', 'tradeNames_list': "['Esomeprazole magnesium', 'Nexium', 'Nexium 24hr']", 'syns_list': "['Esomeprazole (as magnesium)', 'Esomeprazole magnesiumEsomeprazole magnesium hydrate', 'Esomeprazole magnesium trihydrateH199/18 MAGNESIUM ... | general | Distinct, Order By, Similarity Search | Genetic Target, Approval Status |
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