uuid stringlengths 4 8 | template_uuid stringclasses 40
values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 133 622 | execution_results stringlengths 2 1.14M | query_type stringclasses 2
values | sql_category stringclasses 26
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|---|---|---|---|---|---|---|---|---|
Q67.699 | Q67 | What is the top-associated SNP of the gene APOC4 in Cerebellum eQTL omic data for AD and is it functionally significant? | The top-associated SNP for APOC4 in Cerebellum eQTL omic data for AD is rs7252480, which has a multi-SNP SMR p-value of 4.99e-11 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "APOC4" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_4009', 'topRSID': 'rs7252480', 'Disease': 'AD', 'Gene': 'APOC4', 'p_SMR_multi': 4.989487e-11, 'p_HEIDI': 2.48562e-08, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequilib... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1769 | Q67 | What is the top-associated SNP of the gene RP11-20I23.8 in Skeletal Muscle eQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene RP11-20I23.8 in Skeletal Muscle eQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-20I23.8" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%skeletal muscle eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1349592', 'topRSID': 'rs11641539', 'Disease': 'ALS', 'Gene': 'RP11-20I23.8', 'p_SMR_multi': 0.6315369, 'p_HEIDI': 0.9057398, 'Omic_tissue': 'Skeletal Muscle', 'Omic_type': 'Skeletal Muscle eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.301 | Q67 | What is the top-associated SNP of the gene GPNMB in Cortex eQTL GTEx omic data for PD and is it functionally significant? | The top-associated SNP for GPNMB in Cortex eQTL GTEx omic data for PD is rs858273, which has a multi-SNP SMR p-value of 1.40e-06 and a HEIDI of 0.3, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "GPNMB" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cortex eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1260547', 'topRSID': 'rs858273', 'Disease': 'PD', 'Gene': 'GPNMB', 'p_SMR_multi': 1.397219e-06, 'p_HEIDI': 0.3025674, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL GTEx', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1399 | Q67 | What is the top-associated SNP of the gene PMS2P3 in Prefrontal Cortex eQTL omic data for LBD and is it functionally significant? | There are no SNPs within the gene PMS2P3 in Prefrontal Cortex eQTL omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PMS2P3" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%prefrontal cortex eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1228168', 'topRSID': 'rs794369', 'Disease': 'LBD', 'Gene': 'PMS2P3', 'p_SMR_multi': 0.06286178, 'p_HEIDI': 0.3869366, 'Omic_tissue': 'Prefrontal Cortex', 'Omic_type': 'Prefrontal Cortex eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1987 | Q67 | What is the top-associated SNP of the gene B3GALNT2 in Tibial Nerve eQTL omic data for PSP and is it functionally significant? | There are no SNPs within the gene B3GALNT2 in Tibial Nerve eQTL omic data that are significantly associated with PSP, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "B3GALNT2" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%tibial nerve eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1331257', 'topRSID': 'rs696247', 'Disease': 'PSP', 'Gene': 'B3GALNT2', 'p_SMR_multi': 0.1668641, 'p_HEIDI': 0.1354787, 'Omic_tissue': 'Tibial Nerve', 'Omic_type': 'Tibial Nerve eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.102 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Blood mQTL omic data for PSP and is it functionally significant? | The top-associated SNP for MAPT in Whole Blood mQTL omic data for PSP is rs169201, which has a multi-SNP SMR p-value of 3.46e-43 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1041740', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'MAPT', 'p_SMR_multi': 3.1929999999999995e-44, 'p_HEIDI': 3.11336e-12, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Link... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.831 | Q67 | What is the top-associated SNP of the gene KLHL7-AS1 in Hippocampus eQTL omic data for PD and is it functionally significant? | The top-associated SNP for KLHL7-AS1 in Hippocampus eQTL omic data for PD is rs6978827, which has a multi-SNP SMR p-value of 5.03e-07 and a HEIDI of 0.02, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KLHL7-AS1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%hippocampus eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1386053', 'topRSID': 'rs6978827', 'Disease': 'PD', 'Gene': 'KLHL7-AS1', 'p_SMR_multi': 5.026324e-07, 'p_HEIDI': 0.01581612, 'Omic_tissue': 'Hippocampus', 'Omic_type': 'Hippocampus eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.359 | Q67 | What is the top-associated SNP of the gene CRHR1-IT1 in Amygdala eQTL omic data for PD and is it functionally significant? | The top-associated SNP for CRHR1-IT1 in Amygdala eQTL omic data for PD is rs17650860, which has a multi-SNP SMR p-value of 8.81e-11 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CRHR1-IT1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%amygdala eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1603775', 'topRSID': 'rs17650860', 'Disease': 'PD', 'Gene': 'CRHR1-IT1', 'p_SMR_multi': 8.810692e-11, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Amygdala', 'Omic_type': 'Amygdala eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequilib... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.114 | Q67 | What is the top-associated SNP of the gene KLHL7-AS1 in Cerebellum eQTL omic data for PD and is it functionally significant? | The top-associated SNP for KLHL7-AS1 in Cerebellum eQTL omic data for PD is rs10241208, which has a multi-SNP SMR p-value of 9.46e-07 and a HEIDI of 0.02, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KLHL7-AS1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1708093', 'topRSID': 'rs10241208', 'Disease': 'PD', 'Gene': 'KLHL7-AS1', 'p_SMR_multi': 9.46012e-07, 'p_HEIDI': 0.01597826, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1440 | Q67 | What is the top-associated SNP of the gene ARTN in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | There are no SNPs within the gene ARTN in Whole Brain meta-analysis mQTL omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARTN" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_37256', 'topRSID': 'rs1636876', 'Disease': 'AD', 'Gene': 'ARTN', 'p_SMR_multi': 0.2473249, 'p_HEIDI': 0.5876236, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_3725... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1840 | Q67 | What is the top-associated SNP of the gene DOC2A in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for DOC2A in Whole Blood mQTL omic data for AD is rs11863174, which has a multi-SNP SMR p-value of 4.28e-08 and a HEIDI of 0.24, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "DOC2A" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_577418', 'topRSID': 'rs12921753', 'Disease': 'AD', 'Gene': 'DOC2A', 'p_SMR_multi': 5.575261e-12, 'p_HEIDI': 0.3441697, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_577427', 'topRSI... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.952 | Q67 | What is the top-associated SNP of the gene AC008984.7 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for AC008984.7 in Whole Blood eQTL eQTLgen omic data for AD is rs35915840, which has a multi-SNP SMR p-value of 1.28e-06 and a HEIDI of 0.05, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "AC008984.7" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1504181', 'topRSID': 'rs35915840', 'Disease': 'AD', 'Gene': 'AC008984.7', 'p_SMR_multi': 1.27783e-06, 'p_HEIDI': 0.05174984, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1186 | Q67 | What is the top-associated SNP of the gene BCL3 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for BCL3 in Whole Blood mQTL omic data for AD is rs8100197, which has a multi-SNP SMR p-value of 1.52e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "BCL3" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_637414', 'topRSID': 'rs8100197', 'Disease': 'AD', 'Gene': 'BCL3', 'p_SMR_multi': 1.52421e-09, 'p_HEIDI': 7.18848e-11, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequil... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.456 | Q67 | What is the top-associated SNP of the gene CES3 in Cerebellar Hemisphere eQTL omic data for PD and is it functionally significant? | There are no SNPs within the gene CES3 in Cerebellar Hemisphere eQTL omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CES3" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cerebellar hemisphere eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1190959', 'topRSID': 'rs56387824', 'Disease': 'PD', 'Gene': 'CES3', 'p_SMR_multi': 0.2091162, 'p_HEIDI': 0.04053739, 'Omic_tissue': 'Cerebellar Hemisphere', 'Omic_type': 'Cerebellar Hemisphere eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.876 | Q67 | What is the top-associated SNP of the gene MAPT-AS1 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for MAPT-AS1 in Whole Brain meta-analysis mQTL omic data for PD is rs242937, which has a multi-SNP SMR p-value of 3.91e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT-AS1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_491096', 'topRSID': 'rs56280951', 'Disease': 'PD', 'Gene': 'MAPT-AS1', 'p_SMR_multi': 3.97087e-15, 'p_HEIDI': 0.001150121, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkag... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1545 | Q67 | What is the top-associated SNP of the gene STAG3 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for STAG3 in Whole Blood mQTL omic data for AD is rs1727125, which has a multi-SNP SMR p-value of 8.96e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "STAG3" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_585987', 'topRSID': 'rs1636988', 'Disease': 'AD', 'Gene': 'STAG3', 'p_SMR_multi': 1.178562e-11, 'p_HEIDI': 0.0001314553, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1701 | Q67 | What is the top-associated SNP of the gene ARL17A in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for ARL17A in Whole Blood eQTL eQTLgen omic data for AD is rs62074125, which has a multi-SNP SMR p-value of 2.60e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARL17A" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1502457', 'topRSID': 'rs62074125', 'Disease': 'AD', 'Gene': 'ARL17A', 'p_SMR_multi': 2.59862e-07, 'p_HEIDI': 5.662189e-08, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Lin... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1436 | Q67 | What is the top-associated SNP of the gene KANSL1 in Prefrontal Cortex eQTL omic data for PD and is it functionally significant? | The top-associated SNP for KANSL1 in Prefrontal Cortex eQTL omic data for PD is rs2732615, which has a multi-SNP SMR p-value of 1.93e-15 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%prefrontal cortex eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1242276', 'topRSID': 'rs2732615', 'Disease': 'PD', 'Gene': 'KANSL1', 'p_SMR_multi': 1.92913e-15, 'p_HEIDI': 0.0001627713, 'Omic_tissue': 'Prefrontal Cortex', 'Omic_type': 'Prefrontal Cortex eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.915 | Q67 | What is the top-associated SNP of the gene CRHR1-IT1 in Putamen Basal Ganglia eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for CRHR1-IT1 in Putamen Basal Ganglia eQTL omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 2.76e-16 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CRHR1-IT1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%putamen basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1596821', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'CRHR1-IT1', 'p_SMR_multi': 2.759897e-16, 'p_HEIDI': 2.158721e-18, 'Omic_tissue': 'Putamen Basal Ganglia', 'Omic_type': 'Putamen Basal Ganglia eQTL', 'func_sig': 'association meets significance threshold but shows signs... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.310 | Q67 | What is the top-associated SNP of the gene TMPRSS13 in Whole Blood mQTL omic data for AD and is it functionally significant? | There are no SNPs within the gene TMPRSS13 in Whole Blood mQTL omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TMPRSS13" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_610925', 'topRSID': 'rs61900351', 'Disease': 'AD', 'Gene': 'TMPRSS13', 'p_SMR_multi': 0.1834922, 'p_HEIDI': 0.03211964, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_610923', 't... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1257 | Q67 | What is the top-associated SNP of the gene LRRC37A4P in Amygdala eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for LRRC37A4P in Amygdala eQTL omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 1.12e-15 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A4P" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%amygdala eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1604709', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'LRRC37A4P', 'p_SMR_multi': 1.118734e-15, 'p_HEIDI': 2.311169e-19, 'Omic_tissue': 'Amygdala', 'Omic_type': 'Amygdala eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1409 | Q67 | What is the top-associated SNP of the gene AC113607.3 in Whole Brain meta-analysis mQTL omic data for LBD and is it functionally significant? | There are no SNPs within the gene AC113607.3 in Whole Brain meta-analysis mQTL omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "AC113607.3" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_325439', 'topRSID': 'rs74690240', 'Disease': 'LBD', 'Gene': 'AC113607.3', 'p_SMR_multi': 0.5659979, 'p_HEIDI': 0.5270843, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.618 | Q67 | What is the top-associated SNP of the gene CTB-171A8.1 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for CTB-171A8.1 in Whole Brain meta-analysis mQTL omic data for AD is rs10410915, which has a multi-SNP SMR p-value of 2.12e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CTB-171A8.1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_122446', 'topRSID': 'rs10410915', 'Disease': 'AD', 'Gene': 'CTB-171A8.1', 'p_SMR_multi': 3.296369e-08, 'p_HEIDI': 0.0001542126, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of l... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1479 | Q67 | What is the top-associated SNP of the gene ARL17A in Whole Blood eQTL GTEx omic data for PSP and is it functionally significant? | The top-associated SNP for ARL17A in Whole Blood eQTL GTEx omic data for PSP is rs17692129, which has a multi-SNP SMR p-value of 3.95e-17 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARL17A" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1684942', 'topRSID': 'rs17692129', 'Disease': 'PSP', 'Gene': 'ARL17A', 'p_SMR_multi': 3.946778e-17, 'p_HEIDI': 1.870126e-11, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL GTEx', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Link... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.250 | Q67 | What is the top-associated SNP of the gene PCGF3 in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for PCGF3 in Whole Blood mQTL omic data for PD is rs11940788, which has a multi-SNP SMR p-value of 4.30e-07 and a HEIDI of 0.01, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PCGF3" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_996184', 'topRSID': 'rs28743077', 'Disease': 'PD', 'Gene': 'PCGF3', 'p_SMR_multi': 3.407907e-09, 'p_HEIDI': 0.000351479, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.734 | Q67 | What is the top-associated SNP of the gene KANSL1-AS1 in Whole Blood eQTL GTEx omic data for PD and is it functionally significant? | The top-associated SNP for KANSL1-AS1 in Whole Blood eQTL GTEx omic data for PD is rs199456, which has a multi-SNP SMR p-value of 2.47e-14 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1-AS1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1679566', 'topRSID': 'rs199456', 'Disease': 'PD', 'Gene': 'KANSL1-AS1', 'p_SMR_multi': 2.471419e-14, 'p_HEIDI': 0.007679726, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL GTEx', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Link... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.311 | Q67 | What is the top-associated SNP of the gene ELOVL7 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for ELOVL7 in Whole Brain meta-analysis mQTL omic data for PD is rs9291695, which has a multi-SNP SMR p-value of 2.22e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ELOVL7" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_435605', 'topRSID': 'rs34741733', 'Disease': 'PD', 'Gene': 'ELOVL7', 'p_SMR_multi': 3.228168e-07, 'p_HEIDI': 1.693944e-06, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkag... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.236 | Q67 | What is the top-associated SNP of the gene CTD-2020K17.1 in Cerebellar Hemisphere eQTL omic data for PD and is it functionally significant? | The top-associated SNP for CTD-2020K17.1 in Cerebellar Hemisphere eQTL omic data for PD is rs1358071, which has a multi-SNP SMR p-value of 2.44e-06 and a HEIDI of 0.1, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CTD-2020K17.1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cerebellar hemisphere eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1191158', 'topRSID': 'rs1358071', 'Disease': 'PD', 'Gene': 'CTD-2020K17.1', 'p_SMR_multi': 2.43574e-06, 'p_HEIDI': 0.1000749, 'Omic_tissue': 'Cerebellar Hemisphere', 'Omic_type': 'Cerebellar Hemisphere eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.72 | Q67 | What is the top-associated SNP of the gene FMNL1 in Cerebellum eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for FMNL1 in Cerebellum eQTL omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 6.10e-15 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "FMNL1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_22214', 'topRSID': 'rs393152', 'Disease': 'PSP', 'Gene': 'FMNL1', 'p_SMR_multi': 2.005974e-15, 'p_HEIDI': 5.756073e-12, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequil... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.896 | Q67 | What is the top-associated SNP of the gene PVR in Whole Brain eQTL omic data for AD and is it functionally significant? | The top-associated SNP for PVR in Whole Brain eQTL omic data for AD is rs11540084, which has a multi-SNP SMR p-value of 5.00e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PVR" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1611532', 'topRSID': 'rs11540084', 'Disease': 'AD', 'Gene': 'PVR', 'p_SMR_multi': 4.995098e-07, 'p_HEIDI': 2.13819e-06, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1754 | Q67 | What is the top-associated SNP of the gene ZNF251 in Whole Blood mQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene ZNF251 in Whole Blood mQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ZNF251" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_693253', 'topRSID': 'rs71520598', 'Disease': 'ALS', 'Gene': 'ZNF251', 'p_SMR_multi': 0.1607822, 'p_HEIDI': 0.7633429, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_693255', 'top... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.712 | Q67 | What is the top-associated SNP of the gene SPOCK3 in Whole Blood mQTL omic data for FTD and is it functionally significant? | There are no SNPs within the gene SPOCK3 in Whole Blood mQTL omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SPOCK3" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_843475', 'topRSID': 'rs80213399', 'Disease': 'FTD', 'Gene': 'SPOCK3', 'p_SMR_multi': 0.179548, 'p_HEIDI': 0.1528627, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_843476', 'topR... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1383 | Q67 | What is the top-associated SNP of the gene RP11-318M2.3 in Whole Brain eQTL omic data for FTD and is it functionally significant? | There are no SNPs within the gene RP11-318M2.3 in Whole Brain eQTL omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-318M2.3" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%whole brain eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1622954', 'topRSID': 'rs28484802', 'Disease': 'FTD', 'Gene': 'RP11-318M2.3', 'p_SMR_multi': 0.23711, 'p_HEIDI': 0.7025393, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1329 | Q67 | What is the top-associated SNP of the gene CEACAM19 in Caudate Basal Ganglia eQTL omic data for AD and is it functionally significant? | The top-associated SNP for CEACAM19 in Caudate Basal Ganglia eQTL omic data for AD is rs56261258, which has a multi-SNP SMR p-value of 1.46e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CEACAM19" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%caudate basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1268424', 'topRSID': 'rs56261258', 'Disease': 'AD', 'Gene': 'CEACAM19', 'p_SMR_multi': 1.4619e-08, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Caudate Basal Ganglia', 'Omic_type': 'Caudate Basal Ganglia eQTL', 'func_sig': 'association meets significance threshold but shows signs of link... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.624 | Q67 | What is the top-associated SNP of the gene DOC2A in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for DOC2A in Whole Blood mQTL omic data for AD is rs4788213, which has a multi-SNP SMR p-value of 1.71e-08 and a HEIDI of 0.07, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "DOC2A" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_577418', 'topRSID': 'rs12921753', 'Disease': 'AD', 'Gene': 'DOC2A', 'p_SMR_multi': 5.575261e-12, 'p_HEIDI': 0.3441697, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_577427', 'topRSI... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1464 | Q67 | What is the top-associated SNP of the gene GUCY1B3 in Whole Blood mQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene GUCY1B3 in Whole Blood mQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "GUCY1B3" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_702308', 'topRSID': 'rs13107766', 'Disease': 'ALS', 'Gene': 'GUCY1B3', 'p_SMR_multi': 0.1066294, 'p_HEIDI': 0.5812245, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_702307', 'to... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1556 | Q67 | What is the top-associated SNP of the gene AGA in Spinalcord eQTL omic data for LBD and is it functionally significant? | There are no SNPs within the gene AGA in Spinalcord eQTL omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "AGA" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%spinalcord eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_29832', 'topRSID': 'rs13106192', 'Disease': 'LBD', 'Gene': 'AGA', 'p_SMR_multi': 0.2994932, 'p_HEIDI': 0.03397471, 'Omic_tissue': 'Spinalcord', 'Omic_type': 'Spinalcord eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.708 | Q67 | What is the top-associated SNP of the gene KAT8 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for PD and is it functionally significant? | The top-associated SNP for KAT8 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for PD is rs4527034, which has a multi-SNP SMR p-value of 1.02e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KAT8" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1435348', 'topRSID': 'rs4527034', 'Disease': 'PD', 'Gene': 'KAT8', 'p_SMR_multi': 1.024732e-08, 'p_HEIDI': 1.064305e-10, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'association meets significance thresho... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1928 | Q67 | What is the top-associated SNP of the gene STAG3 in Skeletal Muscle eQTL omic data for AD and is it functionally significant? | The top-associated SNP for STAG3 in Skeletal Muscle eQTL omic data for AD is rs2950520, which has a multi-SNP SMR p-value of 2.34e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "STAG3" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%skeletal muscle eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1340317', 'topRSID': 'rs2950520', 'Disease': 'AD', 'Gene': 'STAG3', 'p_SMR_multi': 2.342539e-09, 'p_HEIDI': 0.00463376, 'Omic_tissue': 'Skeletal Muscle', 'Omic_type': 'Skeletal Muscle eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkag... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.614 | Q67 | What is the top-associated SNP of the gene PLXNB2 in Whole Brain meta-analysis mQTL omic data for LBD and is it functionally significant? | There are no SNPs within the gene PLXNB2 in Whole Brain meta-analysis mQTL omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PLXNB2" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_409296', 'topRSID': 'rs28642259', 'Disease': 'LBD', 'Gene': 'PLXNB2', 'p_SMR_multi': 0.01355965, 'p_HEIDI': 0.8129318, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_tex... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.372 | Q67 | What is the top-associated SNP of the gene AIF1 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for AIF1 in Whole Blood mQTL omic data for AD is rs9267576, which has a multi-SNP SMR p-value of 1.27e-06 and a HEIDI of 0.06, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "AIF1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_621023', 'topRSID': 'rs9267576', 'Disease': 'AD', 'Gene': 'AIF1', 'p_SMR_multi': 1.268674e-06, 'p_HEIDI': 0.05810536, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_621027', 'topRSID... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1756 | Q67 | What is the top-associated SNP of the gene CHRNE in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for CHRNE in Whole Blood eQTL eQTLgen omic data for AD is rs72835059, which has a multi-SNP SMR p-value of 2.68e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CHRNE" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1501911', 'topRSID': 'rs72835059', 'Disease': 'AD', 'Gene': 'CHRNE', 'p_SMR_multi': 2.678717e-07, 'p_HEIDI': 0.001296214, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Link... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1669 | Q67 | What is the top-associated SNP of the gene ARHGAP27 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for ARHGAP27 in Whole Brain meta-analysis mQTL omic data for PD is rs1059504, which has a multi-SNP SMR p-value of 3.15e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARHGAP27" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_491057', 'topRSID': 'rs62065376', 'Disease': 'PD', 'Gene': 'ARHGAP27', 'p_SMR_multi': 1.134698e-11, 'p_HEIDI': 0.3072466, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.533 | Q67 | What is the top-associated SNP of the gene GIT1 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | There are no SNPs within the gene GIT1 in Whole Blood eQTL eQTLgen omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "GIT1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1502180', 'topRSID': 'rs894606', 'Disease': 'AD', 'Gene': 'GIT1', 'p_SMR_multi': 0.003979456, 'p_HEIDI': 0.001368465, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1821 | Q67 | What is the top-associated SNP of the gene NSFP1 in Anterior Cingulate Cortex BA24 eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for NSFP1 in Anterior Cingulate Cortex BA24 eQTL omic data for PSP is rs4792831, which has a multi-SNP SMR p-value of 4.31e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "NSFP1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%anterior cingulate cortex ba24 eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1489543', 'topRSID': 'rs4792831', 'Disease': 'PSP', 'Gene': 'NSFP1', 'p_SMR_multi': 4.313718e-10, 'p_HEIDI': 3.095568e-10, 'Omic_tissue': 'Anterior Cingulate Cortex BA24', 'Omic_type': 'Anterior Cingulate Cortex BA24 eQTL', 'func_sig': 'association meets significance threshold b... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1442 | Q67 | What is the top-associated SNP of the gene FAM215B in Tibial Nerve eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for FAM215B in Tibial Nerve eQTL omic data for PSP is rs17692129, which has a multi-SNP SMR p-value of 2.73e-12 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "FAM215B" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%tibial nerve eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1336300', 'topRSID': 'rs17692129', 'Disease': 'PSP', 'Gene': 'FAM215B', 'p_SMR_multi': 2.733178e-12, 'p_HEIDI': 3.699536e-05, 'Omic_tissue': 'Tibial Nerve', 'Omic_type': 'Tibial Nerve eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkag... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.302 | Q67 | What is the top-associated SNP of the gene DGKQ in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for DGKQ in Whole Blood mQTL omic data for PD is rs4690326, which has a multi-SNP SMR p-value of 9.95e-08 and a HEIDI of 0.03, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "DGKQ" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_996294', 'topRSID': 'rs2290402', 'Disease': 'PD', 'Gene': 'DGKQ', 'p_SMR_multi': 3.044298e-09, 'p_HEIDI': 1.349111e-06, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1016 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for MAPT in Whole Blood mQTL omic data for PD is rs112155389, which has a multi-SNP SMR p-value of 3.21e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_948891', 'topRSID': 'rs62063271', 'Disease': 'PD', 'Gene': 'MAPT', 'p_SMR_multi': 6.382411e-15, 'p_HEIDI': 2.368028e-06, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1417 | Q67 | What is the top-associated SNP of the gene ZSCAN9 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for ZSCAN9 in Whole Blood eQTL eQTLgen omic data for AD is rs144344058, which has a multi-SNP SMR p-value of 1.25e-06 and a HEIDI of 0.05, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ZSCAN9" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1494670', 'topRSID': 'rs144344058', 'Disease': 'AD', 'Gene': 'ZSCAN9', 'p_SMR_multi': 1.25261e-06, 'p_HEIDI': 0.04557949, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1567 | Q67 | What is the top-associated SNP of the gene CRHR1-IT1 in Hypothalamus eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for CRHR1-IT1 in Hypothalamus eQTL omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 4.51e-17 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CRHR1-IT1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%hypothalamus eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1464416', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'CRHR1-IT1', 'p_SMR_multi': 4.513623000000001e-17, 'p_HEIDI': 5.729413000000001e-17, 'Omic_tissue': 'Hypothalamus', 'Omic_type': 'Hypothalamus eQTL', 'func_sig': 'association meets significance threshold but shows signs... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1311 | Q67 | What is the top-associated SNP of the gene OPA3 in Tibial Nerve eQTL omic data for PSP and is it functionally significant? | There are no SNPs within the gene OPA3 in Tibial Nerve eQTL omic data that are significantly associated with PSP, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "OPA3" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%tibial nerve eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1336885', 'topRSID': 'rs3745818', 'Disease': 'PSP', 'Gene': 'OPA3', 'p_SMR_multi': 0.2573942, 'p_HEIDI': 0.05539344, 'Omic_tissue': 'Tibial Nerve', 'Omic_type': 'Tibial Nerve eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.862 | Q67 | What is the top-associated SNP of the gene GRN in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD and is it functionally significant? | The top-associated SNP for GRN in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD is rs5848, which has a multi-SNP SMR p-value of 3.18e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "GRN" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1396727', 'topRSID': 'rs5848', 'Disease': 'AD', 'Gene': 'GRN', 'p_SMR_multi': 3.175137e-07, 'p_HEIDI': 0.0003317978, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'association meets significance threshold b... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.591 | Q67 | What is the top-associated SNP of the gene CRHR1-IT1 in Whole Brain eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for CRHR1-IT1 in Whole Brain eQTL omic data for PSP is rs11012, which has a multi-SNP SMR p-value of 7.58e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CRHR1-IT1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole brain eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1646041', 'topRSID': 'rs11012', 'Disease': 'PSP', 'Gene': 'CRHR1-IT1', 'p_SMR_multi': 7.584608e-10, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.485 | Q67 | What is the top-associated SNP of the gene RP11-514P8.2 in Whole Brain meta-analysis mQTL omic data for LBD and is it functionally significant? | There are no SNPs within the gene RP11-514P8.2 in Whole Brain meta-analysis mQTL omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-514P8.2" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_355942', 'topRSID': 'rs41275227', 'Disease': 'LBD', 'Gene': 'RP11-514P8.2', 'p_SMR_multi': 0.166392, 'p_HEIDI': 0.2746905, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1473 | Q67 | What is the top-associated SNP of the gene MAT1A in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for MAT1A in Whole Brain meta-analysis mQTL omic data for AD is rs1890578, which has a multi-SNP SMR p-value of 1.43e-06 and a HEIDI of 0.15, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAT1A" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_85765', 'topRSID': 'rs10749551', 'Disease': 'AD', 'Gene': 'MAT1A', 'p_SMR_multi': 2.281899e-07, 'p_HEIDI': 0.0009813646, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1784 | Q67 | What is the top-associated SNP of the gene PES1 in Whole Blood mQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene PES1 in Whole Blood mQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PES1" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_676207', 'topRSID': 'rs2240433', 'Disease': 'ALS', 'Gene': 'PES1', 'p_SMR_multi': 0.3540101, 'p_HEIDI': 0.1300431, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_676204', 'topRSI... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.644 | Q67 | What is the top-associated SNP of the gene LRRC37A2 in Frontal Cortex BA9 eQTL omic data for PD and is it functionally significant? | The top-associated SNP for LRRC37A2 in Frontal Cortex BA9 eQTL omic data for PD is rs4074462, which has a multi-SNP SMR p-value of 8.74e-12 and a HEIDI of 0.47, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A2" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%frontal cortex ba9 eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1168842', 'topRSID': 'rs4074462', 'Disease': 'PD', 'Gene': 'LRRC37A2', 'p_SMR_multi': 8.74303e-12, 'p_HEIDI': 0.4723248, 'Omic_tissue': 'Frontal Cortex', 'Omic_type': 'Frontal Cortex BA9 eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.357 | Q67 | What is the top-associated SNP of the gene PPFIA4 in Whole Brain meta-analysis mQTL omic data for FTD and is it functionally significant? | There are no SNPs within the gene PPFIA4 in Whole Brain meta-analysis mQTL omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PPFIA4" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_232297', 'topRSID': 'rs10920556', 'Disease': 'FTD', 'Gene': 'PPFIA4', 'p_SMR_multi': 0.185709, 'p_HEIDI': 0.7369503, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1128 | Q67 | What is the top-associated SNP of the gene TREML2 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for TREML2 in Whole Brain meta-analysis mQTL omic data for AD is rs2006080, which has a multi-SNP SMR p-value of 2.08e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TREML2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_67040', 'topRSID': 'rs3800342', 'Disease': 'AD', 'Gene': 'TREML2', 'p_SMR_multi': 1.208504e-10, 'p_HEIDI': 0.0007742865, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.439 | Q67 | What is the top-associated SNP of the gene GPNMB in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for GPNMB in Whole Brain meta-analysis mQTL omic data for PD is rs199357, which has a multi-SNP SMR p-value of 2.46e-07 and a HEIDI of 0.28, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "GPNMB" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_447897', 'topRSID': 'rs199357', 'Disease': 'PD', 'Gene': 'GPNMB', 'p_SMR_multi': 1.890519e-08, 'p_HEIDI': 0.02394197, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_447... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1121 | Q67 | What is the top-associated SNP of the gene PLCL1 in Whole Blood eQTL GTEx omic data for FTD and is it functionally significant? | There are no SNPs within the gene PLCL1 in Whole Blood eQTL GTEx omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PLCL1" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%whole blood eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1661783', 'topRSID': 'rs12329164', 'Disease': 'FTD', 'Gene': 'PLCL1', 'p_SMR_multi': 0.6644351, 'p_HEIDI': 0.5683536, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL GTEx', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1103 | Q67 | What is the top-associated SNP of the gene FHL2 in Cortex eQTL metaBrain omic data for ALS and is it functionally significant? | There are no SNPs within the gene FHL2 in Cortex eQTL metaBrain omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "FHL2" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%cortex eqtl metabrain%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1117986', 'topRSID': 'rs72945049', 'Disease': 'ALS', 'Gene': 'FHL2', 'p_SMR_multi': 0.6955063, 'p_HEIDI': 0.9795396, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL metaBrain', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1348 | Q67 | What is the top-associated SNP of the gene AC005154.7 in Hypothalamus eQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene AC005154.7 in Hypothalamus eQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "AC005154.7" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%hypothalamus eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1455598', 'topRSID': 'rs2270007', 'Disease': 'ALS', 'Gene': 'AC005154.7', 'p_SMR_multi': 0.2942886, 'p_HEIDI': 0.7524773, 'Omic_tissue': 'Hypothalamus', 'Omic_type': 'Hypothalamus eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.597 | Q67 | What is the top-associated SNP of the gene APOE in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for APOE in Whole Brain meta-analysis mQTL omic data for AD is rs73050293, which has a multi-SNP SMR p-value of 2.09e-11 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "APOE" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_122464', 'topRSID': 'rs73050293', 'Disease': 'AD', 'Gene': 'APOE', 'p_SMR_multi': 3.931424e-14, 'p_HEIDI': 1.590816e-11, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1368 | Q67 | What is the top-associated SNP of the gene ADARB2 in Whole Blood mQTL omic data for AD and is it functionally significant? | There are no SNPs within the gene ADARB2 in Whole Blood mQTL omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ADARB2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_570525', 'topRSID': 'rs74706128', 'Disease': 'AD', 'Gene': 'ADARB2', 'p_SMR_multi': 0.00402699, 'p_HEIDI': 0.6454659, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_570418', 'top... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1401 | Q67 | What is the top-associated SNP of the gene EFNA3 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for EFNA3 in Whole Brain meta-analysis mQTL omic data for PD is rs3765087, which has a multi-SNP SMR p-value of 1.13e-06 and a HEIDI of 0.14, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "EFNA3" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_415496', 'topRSID': 'rs3765087', 'Disease': 'PD', 'Gene': 'EFNA3', 'p_SMR_multi': 1.128061e-06, 'p_HEIDI': 0.1447173, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_415... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.753 | Q67 | What is the top-associated SNP of the gene RP11-259G18.2 in Tibial Nerve eQTL omic data for PD and is it functionally significant? | The top-associated SNP for RP11-259G18.2 in Tibial Nerve eQTL omic data for PD is rs2532363, which has a multi-SNP SMR p-value of 8.57e-13 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.2" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%tibial nerve eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1328935', 'topRSID': 'rs2532363', 'Disease': 'PD', 'Gene': 'RP11-259G18.2', 'p_SMR_multi': 8.566808e-13, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Tibial Nerve', 'Omic_type': 'Tibial Nerve eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.259 | Q67 | What is the top-associated SNP of the gene CRHR1 in Cortex eQTL metaBrain omic data for PD and is it functionally significant? | The top-associated SNP for CRHR1 in Cortex eQTL metaBrain omic data for PD is rs2668632, which has a multi-SNP SMR p-value of 2.83e-12 and a HEIDI of 0.14, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CRHR1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cortex eqtl metabrain%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1147253', 'topRSID': 'rs2668632', 'Disease': 'PD', 'Gene': 'CRHR1', 'p_SMR_multi': 2.828437e-12, 'p_HEIDI': 0.1385602, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL metaBrain', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1687 | Q67 | What is the top-associated SNP of the gene TFAM in Cortex eQTL metaBrain omic data for PD and is it functionally significant? | There are no SNPs within the gene TFAM in Cortex eQTL metaBrain omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TFAM" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cortex eqtl metabrain%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1139089', 'topRSID': 'rs2279340', 'Disease': 'PD', 'Gene': 'TFAM', 'p_SMR_multi': 0.1443903, 'p_HEIDI': 0.9738334, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL metaBrain', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1723 | Q67 | What is the top-associated SNP of the gene PLEC in Whole Brain meta-analysis mQTL omic data for PSP and is it functionally significant? | There are no SNPs within the gene PLEC in Whole Brain meta-analysis mQTL omic data that are significantly associated with PSP, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PLEC" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_537563', 'topRSID': 'rs6984820', 'Disease': 'PSP', 'Gene': 'PLEC', 'p_SMR_multi': 0.6349835, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_5375... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.544 | Q67 | What is the top-associated SNP of the gene ARL17A in Liver eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for ARL17A in Liver eQTL omic data for PSP is rs17692129, which has a multi-SNP SMR p-value of 5.35e-11 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARL17A" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%liver eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1478194', 'topRSID': 'rs17692129', 'Disease': 'PSP', 'Gene': 'ARL17A', 'p_SMR_multi': 5.347998e-11, 'p_HEIDI': 0.0002251332, 'Omic_tissue': 'Liver', 'Omic_type': 'Liver eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequilibriu... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.792 | Q67 | What is the top-associated SNP of the gene LRRC37A in Cerebellar Hemisphere eQTL omic data for PD and is it functionally significant? | The top-associated SNP for LRRC37A in Cerebellar Hemisphere eQTL omic data for PD is rs3874943, which has a multi-SNP SMR p-value of 8.91e-11 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cerebellar hemisphere eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1191177', 'topRSID': 'rs3874943', 'Disease': 'PD', 'Gene': 'LRRC37A', 'p_SMR_multi': 8.908998e-11, 'p_HEIDI': 2.961702e-05, 'Omic_tissue': 'Cerebellar Hemisphere', 'Omic_type': 'Cerebellar Hemisphere eQTL', 'func_sig': 'association meets significance threshold but shows signs of... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1484 | Q67 | What is the top-associated SNP of the gene GPNMB in Putamen Basal Ganglia eQTL omic data for PD and is it functionally significant? | The top-associated SNP for GPNMB in Putamen Basal Ganglia eQTL omic data for PD is rs199357, which has a multi-SNP SMR p-value of 9.66e-07 and a HEIDI of 0.35, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "GPNMB" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%putamen basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1593746', 'topRSID': 'rs199357', 'Disease': 'PD', 'Gene': 'GPNMB', 'p_SMR_multi': 9.655041e-07, 'p_HEIDI': 0.3548551, 'Omic_tissue': 'Putamen Basal Ganglia', 'Omic_type': 'Putamen Basal Ganglia eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.420 | Q67 | What is the top-associated SNP of the gene CALN1 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | There are no SNPs within the gene CALN1 in Whole Brain meta-analysis mQTL omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CALN1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_73466', 'topRSID': 'rs2968511', 'Disease': 'AD', 'Gene': 'CALN1', 'p_SMR_multi': 0.141409, 'p_HEIDI': 0.9222489, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_7346... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1849 | Q67 | What is the top-associated SNP of the gene LRRC37A in Whole Brain eQTL omic data for AD and is it functionally significant? | The top-associated SNP for LRRC37A in Whole Brain eQTL omic data for AD is rs62062280, which has a multi-SNP SMR p-value of 9.26e-08 and a HEIDI of 0.03, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1610870', 'topRSID': 'rs62062280', 'Disease': 'AD', 'Gene': 'LRRC37A', 'p_SMR_multi': 9.258575e-08, 'p_HEIDI': 0.03126041, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1920 | Q67 | What is the top-associated SNP of the gene PLEKHM1 in Skeletal Muscle eQTL omic data for PD and is it functionally significant? | The top-associated SNP for PLEKHM1 in Skeletal Muscle eQTL omic data for PD is rs12947718, which has a multi-SNP SMR p-value of 7.76e-12 and a HEIDI of 0.04, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PLEKHM1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%skeletal muscle eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1370536', 'topRSID': 'rs12947718', 'Disease': 'PD', 'Gene': 'PLEKHM1', 'p_SMR_multi': 7.763854e-12, 'p_HEIDI': 0.03535971, 'Omic_tissue': 'Skeletal Muscle', 'Omic_type': 'Skeletal Muscle eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1099 | Q67 | What is the top-associated SNP of the gene PLEKHM1 in Putamen Basal Ganglia eQTL omic data for PD and is it functionally significant? | The top-associated SNP for PLEKHM1 in Putamen Basal Ganglia eQTL omic data for PD is rs62065442, which has a multi-SNP SMR p-value of 2.87e-07 and a HEIDI of 0.03, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PLEKHM1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%putamen basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1594918', 'topRSID': 'rs62065442', 'Disease': 'PD', 'Gene': 'PLEKHM1', 'p_SMR_multi': 2.866553e-07, 'p_HEIDI': 0.03026128, 'Omic_tissue': 'Putamen Basal Ganglia', 'Omic_type': 'Putamen Basal Ganglia eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.845 | Q67 | What is the top-associated SNP of the gene LRRC37A2 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for LRRC37A2 in Whole Blood eQTL eQTLgen omic data for AD is rs112560196, which has a multi-SNP SMR p-value of 4.53e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1502456', 'topRSID': 'rs112560196', 'Disease': 'AD', 'Gene': 'LRRC37A2', 'p_SMR_multi': 4.532871e-08, 'p_HEIDI': 0.002387193, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.68 | Q67 | What is the top-associated SNP of the gene KIF1C in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for KIF1C in Whole Blood mQTL omic data for AD is rs3786046, which has a multi-SNP SMR p-value of 5.98e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KIF1C" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_589041', 'topRSID': 'rs3786046', 'Disease': 'AD', 'Gene': 'KIF1C', 'p_SMR_multi': 5.975266e-08, 'p_HEIDI': 0.006755758, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1698 | Q67 | What is the top-associated SNP of the gene LRRC37A2 in Whole Blood eQTL GTEx omic data for AD and is it functionally significant? | The top-associated SNP for LRRC37A2 in Whole Blood eQTL GTEx omic data for AD is rs7502718, which has a multi-SNP SMR p-value of 1.16e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1652505', 'topRSID': 'rs7502718', 'Disease': 'AD', 'Gene': 'LRRC37A2', 'p_SMR_multi': 1.163314e-06, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL GTEx', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage D... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1733 | Q67 | What is the top-associated SNP of the gene TREML5P in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for TREML5P in Whole Blood eQTL eQTLgen omic data for AD is rs6458200, which has a multi-SNP SMR p-value of 1.12e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TREML5P" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1494872', 'topRSID': 'rs6458200', 'Disease': 'AD', 'Gene': 'TREML5P', 'p_SMR_multi': 1.116296e-10, 'p_HEIDI': 0.0002742431, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Li... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.380 | Q67 | What is the top-associated SNP of the gene RTN4RL1 in Whole Blood mQTL omic data for FTD and is it functionally significant? | There are no SNPs within the gene RTN4RL1 in Whole Blood mQTL omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RTN4RL1" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_830799', 'topRSID': 'rs9898872', 'Disease': 'FTD', 'Gene': 'RTN4RL1', 'p_SMR_multi': 0.5429191, 'p_HEIDI': 0.6667066, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_830806', 'top... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.240 | Q67 | What is the top-associated SNP of the gene NSFP1 in Nucleus Accumbens Basal Ganglia omic data for PSP and is it functionally significant? | The top-associated SNP for NSFP1 in Nucleus Accumbens Basal Ganglia omic data for PSP is rs4792831, which has a multi-SNP SMR p-value of 6.61e-12 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "NSFP1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%nucleus accumbens basal ganglia%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1732401', 'topRSID': 'rs4792831', 'Disease': 'PSP', 'Gene': 'NSFP1', 'p_SMR_multi': 6.608576e-12, 'p_HEIDI': 8.976722e-09, 'Omic_tissue': 'Nucleus Accumbens Basal', 'Omic_type': 'Nucleus Accumbens Basal Ganglia', 'func_sig': 'association meets significance threshold but shows si... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.257 | Q67 | What is the top-associated SNP of the gene RP11-177C12.1 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | There are no SNPs within the gene RP11-177C12.1 in Whole Blood eQTL eQTLgen omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-177C12.1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1493434', 'topRSID': 'rs3775792', 'Disease': 'AD', 'Gene': 'RP11-177C12.1', 'p_SMR_multi': 0.03983258, 'p_HEIDI': 0.02244375, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1032 | Q67 | What is the top-associated SNP of the gene DOCK1 in Whole Brain meta-analysis mQTL omic data for LBD and is it functionally significant? | There are no SNPs within the gene DOCK1 in Whole Brain meta-analysis mQTL omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "DOCK1" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_368751', 'topRSID': 'rs67989516', 'Disease': 'LBD', 'Gene': 'DOCK1', 'p_SMR_multi': 0.06835609, 'p_HEIDI': 0.2445526, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.30 | Q67 | What is the top-associated SNP of the gene LRRC37A2 in Spinalcord eQTL omic data for PD and is it functionally significant? | The top-associated SNP for LRRC37A2 in Spinalcord eQTL omic data for PD is rs58879558, which has a multi-SNP SMR p-value of 4.69e-09 and a HEIDI of 0.27, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A2" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%spinalcord eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_30031', 'topRSID': 'rs58879558', 'Disease': 'PD', 'Gene': 'LRRC37A2', 'p_SMR_multi': 4.692435e-09, 'p_HEIDI': 0.2679779, 'Omic_tissue': 'Spinalcord', 'Omic_type': 'Spinalcord eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.293 | Q67 | What is the top-associated SNP of the gene PVRIG in Hypothalamus eQTL omic data for AD and is it functionally significant? | The top-associated SNP for PVRIG in Hypothalamus eQTL omic data for AD is rs1623264, which has a multi-SNP SMR p-value of 1.03e-06 and a HEIDI of 0.06, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PVRIG" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%hypothalamus eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1453490', 'topRSID': 'rs1623264', 'Disease': 'AD', 'Gene': 'PVRIG', 'p_SMR_multi': 1.030527e-06, 'p_HEIDI': 0.0581387, 'Omic_tissue': 'Hypothalamus', 'Omic_type': 'Hypothalamus eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1886 | Q67 | What is the top-associated SNP of the gene TMEM175 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for TMEM175 in Whole Brain meta-analysis mQTL omic data for PD is rs10008187, which has a multi-SNP SMR p-value of 6.69e-10 and a HEIDI of 0.31, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TMEM175" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_429841', 'topRSID': 'rs10008187', 'Disease': 'PD', 'Gene': 'TMEM175', 'p_SMR_multi': 4.414637e-10, 'p_HEIDI': 0.4333231, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1823 | Q67 | What is the top-associated SNP of the gene LILRB2 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for LILRB2 in Whole Blood eQTL eQTLgen omic data for AD is rs12984962, which has a multi-SNP SMR p-value of 1.20e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LILRB2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1504179', 'topRSID': 'rs12984962', 'Disease': 'AD', 'Gene': 'LILRB2', 'p_SMR_multi': 1.202451e-06, 'p_HEIDI': 9.629543e-05, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Li... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.620 | Q67 | What is the top-associated SNP of the gene LLGL1 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for LLGL1 in Whole Blood mQTL omic data for AD is rs2290507, which has a multi-SNP SMR p-value of 1.18e-06 and a HEIDI of 0.26, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LLGL1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_589834', 'topRSID': 'rs2290507', 'Disease': 'AD', 'Gene': 'LLGL1', 'p_SMR_multi': 1.175945e-06, 'p_HEIDI': 0.2599892, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_589833', 'topRSID... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1667 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for MAPT in Whole Brain meta-analysis mQTL omic data for PD is rs78599197, which has a multi-SNP SMR p-value of 2.73e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_491114', 'topRSID': 'rs17652121', 'Disease': 'PD', 'Gene': 'MAPT', 'p_SMR_multi': 4.729064e-14, 'p_HEIDI': 0.04416005, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_49... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.850 | Q67 | What is the top-associated SNP of the gene KANSL1 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for KANSL1 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for PSP is rs169201, which has a multi-SNP SMR p-value of 6.59e-36 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT 10... | [{'UUID': 'NDD_SMR_genes_all_update_text_1444272', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'KANSL1', 'p_SMR_multi': 6.592123999999999e-36, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'association meets significance t... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.215 | Q67 | What is the top-associated SNP of the gene IGSF9B in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for IGSF9B in Whole Blood mQTL omic data for PD is rs329667, which has a multi-SNP SMR p-value of 6.66e-09 and a HEIDI of 0.48, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "IGSF9B" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_961101', 'topRSID': 'rs3802920', 'Disease': 'PD', 'Gene': 'IGSF9B', 'p_SMR_multi': 1.22563e-10, 'p_HEIDI': 0.0001625568, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.524 | Q67 | What is the top-associated SNP of the gene RP11-259G18.2 in Hippocampus eQTL omic data for PD and is it functionally significant? | The top-associated SNP for RP11-259G18.2 in Hippocampus eQTL omic data for PD is rs199456, which has a multi-SNP SMR p-value of 5.53e-11 and a HEIDI of 0.01, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.2" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%hippocampus eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1386992', 'topRSID': 'rs199456', 'Disease': 'PD', 'Gene': 'RP11-259G18.2', 'p_SMR_multi': 5.526697e-11, 'p_HEIDI': 0.01264907, 'Omic_tissue': 'Hippocampus', 'Omic_type': 'Hippocampus eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.477 | Q67 | What is the top-associated SNP of the gene BFSP1 in Whole Blood mQTL omic data for PD and is it functionally significant? | There are no SNPs within the gene BFSP1 in Whole Blood mQTL omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "BFSP1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1022222', 'topRSID': 'rs3790316', 'Disease': 'PD', 'Gene': 'BFSP1', 'p_SMR_multi': 0.7782665, 'p_HEIDI': 0.7771181, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_1022226', 'topR... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1327 | Q67 | What is the top-associated SNP of the gene IGSF9B in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for IGSF9B in Whole Blood mQTL omic data for PD is rs11223627, which has a multi-SNP SMR p-value of 1.08e-08 and a HEIDI of 0.02, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "IGSF9B" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_961101', 'topRSID': 'rs3802920', 'Disease': 'PD', 'Gene': 'IGSF9B', 'p_SMR_multi': 1.22563e-10, 'p_HEIDI': 0.0001625568, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1433 | Q67 | What is the top-associated SNP of the gene TSPYL5 in Cortex eQTL metaBrain omic data for ALS and is it functionally significant? | There are no SNPs within the gene TSPYL5 in Cortex eQTL metaBrain omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TSPYL5" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%cortex eqtl metabrain%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1115866', 'topRSID': 'rs28669903', 'Disease': 'ALS', 'Gene': 'TSPYL5', 'p_SMR_multi': 0.5291059, 'p_HEIDI': 0.6075126, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL metaBrain', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.123 | Q67 | What is the top-associated SNP of the gene KANSL1-AS1 in Substantia nigra eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for KANSL1-AS1 in Substantia nigra eQTL omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 3.35e-12 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1-AS1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%substantia nigra eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1452482', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'KANSL1-AS1', 'p_SMR_multi': 3.350931e-12, 'p_HEIDI': 3.216973e-05, 'Omic_tissue': 'Substantia nigra', 'Omic_type': 'Substantia nigra eQTL', 'func_sig': 'association meets significance threshold but shows signs of linka... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1351 | Q67 | What is the top-associated SNP of the gene FBXW8 in Whole Blood mQTL omic data for PD and is it functionally significant? | There are no SNPs within the gene FBXW8 in Whole Blood mQTL omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "FBXW8" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1005592', 'topRSID': 'rs4299000', 'Disease': 'PD', 'Gene': 'FBXW8', 'p_SMR_multi': 0.2664658, 'p_HEIDI': 0.5044972, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_1005591', 'topR... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1942 | Q67 | What is the top-associated SNP of the gene LRRC37A2 in Hippocampus eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for LRRC37A2 in Hippocampus eQTL omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 3.25e-18 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A2" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%hippocampus eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1388487', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'LRRC37A2', 'p_SMR_multi': 3.252101e-18, 'p_HEIDI': 1.274896e-19, 'Omic_tissue': 'Hippocampus', 'Omic_type': 'Hippocampus eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
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