uuid stringlengths 4 8 | template_uuid stringclasses 40
values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 133 622 | execution_results stringlengths 2 1.14M | query_type stringclasses 2
values | sql_category stringclasses 26
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|---|---|---|---|---|---|---|---|---|
Q67.176 | Q67 | What is the top-associated SNP of the gene STAG3 in Cortex eQTL GTEx omic data for AD and is it functionally significant? | The top-associated SNP for STAG3 in Cortex eQTL GTEx omic data for AD is rs1727140, which has a multi-SNP SMR p-value of 1.48e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "STAG3" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%cortex eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1245517', 'topRSID': 'rs1727140', 'Disease': 'AD', 'Gene': 'STAG3', 'p_SMR_multi': 1.477897e-07, 'p_HEIDI': 0.0009789817, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL GTEx', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequili... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.824 | Q67 | What is the top-associated SNP of the gene LY6G5C in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | There are no SNPs within the gene LY6G5C in Whole Brain meta-analysis mQTL omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LY6G5C" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_441604', 'topRSID': 'rs12529661', 'Disease': 'PD', 'Gene': 'LY6G5C', 'p_SMR_multi': 0.3074972, 'p_HEIDI': 0.4184643, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.983 | Q67 | What is the top-associated SNP of the gene AGPAT2 in Whole Blood mQTL omic data for PSP and is it functionally significant? | There are no SNPs within the gene AGPAT2 in Whole Blood mQTL omic data that are significantly associated with PSP, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "AGPAT2" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1082949', 'topRSID': 'rs3812611', 'Disease': 'PSP', 'Gene': 'AGPAT2', 'p_SMR_multi': 0.3607675, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_1082948', 'topR... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1476 | Q67 | What is the top-associated SNP of the gene CYB5D2 in Whole Brain meta-analysis mQTL omic data for FTD and is it functionally significant? | There are no SNPs within the gene CYB5D2 in Whole Brain meta-analysis mQTL omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CYB5D2" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_300858', 'topRSID': 'rs62072182', 'Disease': 'FTD', 'Gene': 'CYB5D2', 'p_SMR_multi': 0.3994997, 'p_HEIDI': 0.09062491, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_tex... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1262 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for MAPT in Whole Blood mQTL omic data for PD is rs111541901, which has a multi-SNP SMR p-value of 5.20e-14 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_948891', 'topRSID': 'rs62063271', 'Disease': 'PD', 'Gene': 'MAPT', 'p_SMR_multi': 6.382411e-15, 'p_HEIDI': 2.368028e-06, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1280 | Q67 | What is the top-associated SNP of the gene DND1P1 in Anterior Cingulate Cortex BA24 eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for DND1P1 in Anterior Cingulate Cortex BA24 eQTL omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 3.91e-13 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "DND1P1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%anterior cingulate cortex ba24 eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1489534', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'DND1P1', 'p_SMR_multi': 3.907491e-13, 'p_HEIDI': 3.669264e-11, 'Omic_tissue': 'Anterior Cingulate Cortex BA24', 'Omic_type': 'Anterior Cingulate Cortex BA24 eQTL', 'func_sig': 'association meets significance threshold ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.751 | Q67 | What is the top-associated SNP of the gene DND1P1 in Skeletal Muscle eQTL omic data for AD and is it functionally significant? | The top-associated SNP for DND1P1 in Skeletal Muscle eQTL omic data for AD is rs55974014, which has a multi-SNP SMR p-value of 1.92e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "DND1P1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%skeletal muscle eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1343149', 'topRSID': 'rs55974014', 'Disease': 'AD', 'Gene': 'DND1P1', 'p_SMR_multi': 1.91696e-06, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Skeletal Muscle', 'Omic_type': 'Skeletal Muscle eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.561 | Q67 | What is the top-associated SNP of the gene ZNF668 in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for ZNF668 in Whole Blood mQTL omic data for PD is rs11647284, which has a multi-SNP SMR p-value of 3.03e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ZNF668" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_974686', 'topRSID': 'rs11647284', 'Disease': 'PD', 'Gene': 'ZNF668', 'p_SMR_multi': 3.029697e-07, 'p_HEIDI': 1.827066e-05, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dis... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.81 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for MAPT in Whole Blood mQTL omic data for AD is rs62056790, which has a multi-SNP SMR p-value of 3.12e-07 and a HEIDI of 0.09, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_591203', 'topRSID': 'rs17689882', 'Disease': 'AD', 'Gene': 'MAPT', 'p_SMR_multi': 2.532079e-07, 'p_HEIDI': 0.02723276, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_591210', 'topRSI... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1042 | Q67 | What is the top-associated SNP of the gene RP11-17E13.2 in Amygdala eQTL omic data for AD and is it functionally significant? | There are no SNPs within the gene RP11-17E13.2 in Amygdala eQTL omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-17E13.2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%amygdala eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1597193', 'topRSID': 'rs6666150', 'Disease': 'AD', 'Gene': 'RP11-17E13.2', 'p_SMR_multi': 0.5911743, 'p_HEIDI': 0.2738423, 'Omic_tissue': 'Amygdala', 'Omic_type': 'Amygdala eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1314 | Q67 | What is the top-associated SNP of the gene CEACAM19 in Skeletal Muscle eQTL omic data for AD and is it functionally significant? | The top-associated SNP for CEACAM19 in Skeletal Muscle eQTL omic data for AD is rs3760624, which has a multi-SNP SMR p-value of 1.70e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CEACAM19" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%skeletal muscle eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1343793', 'topRSID': 'rs3760624', 'Disease': 'AD', 'Gene': 'CEACAM19', 'p_SMR_multi': 1.704695e-07, 'p_HEIDI': 0.0001395805, 'Omic_tissue': 'Skeletal Muscle', 'Omic_type': 'Skeletal Muscle eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ L... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.33 | Q67 | What is the top-associated SNP of the gene CMYA5 in Whole Blood mQTL omic data for FTD and is it functionally significant? | There are no SNPs within the gene CMYA5 in Whole Blood mQTL omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CMYA5" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_772489', 'topRSID': 'rs72768842', 'Disease': 'FTD', 'Gene': 'CMYA5', 'p_SMR_multi': 0.2620294, 'p_HEIDI': 0.3017941, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_772488', 'topR... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1739 | Q67 | What is the top-associated SNP of the gene ARL17A in Putamen Basal Ganglia eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for ARL17A in Putamen Basal Ganglia eQTL omic data for PSP is rs169201, which has a multi-SNP SMR p-value of 4.14e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARL17A" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%putamen basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1596830', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'ARL17A', 'p_SMR_multi': 4.135643e-10, 'p_HEIDI': 2.406068e-05, 'Omic_tissue': 'Putamen Basal Ganglia', 'Omic_type': 'Putamen Basal Ganglia eQTL', 'func_sig': 'association meets significance threshold but shows signs of ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.358 | Q67 | What is the top-associated SNP of the gene RBP7 in Whole Blood mQTL omic data for FTD and is it functionally significant? | There are no SNPs within the gene RBP7 in Whole Blood mQTL omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RBP7" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_778901', 'topRSID': 'rs6661806', 'Disease': 'FTD', 'Gene': 'RBP7', 'p_SMR_multi': 0.1374462, 'p_HEIDI': 0.2989946, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_778899', 'topRSI... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1077 | Q67 | What is the top-associated SNP of the gene ARL17A in Cortex eQTL metaBrain omic data for AD and is it functionally significant? | The top-associated SNP for ARL17A in Cortex eQTL metaBrain omic data for AD is rs2532233, which has a multi-SNP SMR p-value of 1.16e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARL17A" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%cortex eqtl metabrain%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1106834', 'topRSID': 'rs2532233', 'Disease': 'AD', 'Gene': 'ARL17A', 'p_SMR_multi': 1.156287e-07, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL metaBrain', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequil... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1692 | Q67 | What is the top-associated SNP of the gene RP11-798G7.8 in Tibial Nerve eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for RP11-798G7.8 in Tibial Nerve eQTL omic data for PSP is rs12373139, which has a multi-SNP SMR p-value of 3.12e-12 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-798G7.8" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%tibial nerve eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1336283', 'topRSID': 'rs12373139', 'Disease': 'PSP', 'Gene': 'RP11-798G7.8', 'p_SMR_multi': 3.121197e-12, 'p_HEIDI': 0.0009714135, 'Omic_tissue': 'Tibial Nerve', 'Omic_type': 'Tibial Nerve eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ L... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.127 | Q67 | What is the top-associated SNP of the gene RP11-259G18.1 in Cerebellar Hemisphere eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for RP11-259G18.1 in Cerebellar Hemisphere eQTL omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 8.05e-21 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%cerebellar hemisphere eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1194220', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'RP11-259G18.1', 'p_SMR_multi': 8.051304e-21, 'p_HEIDI': 4.676515e-22, 'Omic_tissue': 'Cerebellar Hemisphere', 'Omic_type': 'Cerebellar Hemisphere eQTL', 'func_sig': 'association meets significance threshold but shows s... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1031 | Q67 | What is the top-associated SNP of the gene AC012146.7 in Tibial Nerve eQTL omic data for AD and is it functionally significant? | The top-associated SNP for AC012146.7 in Tibial Nerve eQTL omic data for AD is rs113831399, which has a multi-SNP SMR p-value of 2.72e-07 and a HEIDI of 0.11, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "AC012146.7" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%tibial nerve eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1291507', 'topRSID': 'rs113831399', 'Disease': 'AD', 'Gene': 'AC012146.7', 'p_SMR_multi': 2.72283e-07, 'p_HEIDI': 0.1054384, 'Omic_tissue': 'Tibial Nerve', 'Omic_type': 'Tibial Nerve eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.399 | Q67 | What is the top-associated SNP of the gene ARL17A in Frontal Cortex BA9 eQTL omic data for PD and is it functionally significant? | The top-associated SNP for ARL17A in Frontal Cortex BA9 eQTL omic data for PD is rs62056812, which has a multi-SNP SMR p-value of 2.86e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARL17A" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%frontal cortex ba9 eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1168843', 'topRSID': 'rs62056812', 'Disease': 'PD', 'Gene': 'ARL17A', 'p_SMR_multi': 2.856301e-10, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Frontal Cortex', 'Omic_type': 'Frontal Cortex BA9 eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linka... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.444 | Q67 | What is the top-associated SNP of the gene LRRC37A in Caudate Basal Ganglia eQTL omic data for PD and is it functionally significant? | The top-associated SNP for LRRC37A in Caudate Basal Ganglia eQTL omic data for PD is rs3874943, which has a multi-SNP SMR p-value of 2.09e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%caudate basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1281360', 'topRSID': 'rs3874943', 'Disease': 'PD', 'Gene': 'LRRC37A', 'p_SMR_multi': 2.0939e-08, 'p_HEIDI': 4.823831e-07, 'Omic_tissue': 'Caudate Basal Ganglia', 'Omic_type': 'Caudate Basal Ganglia eQTL', 'func_sig': 'association meets significance threshold but shows signs of l... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.166 | Q67 | What is the top-associated SNP of the gene ANGPTL2 in Skeletal Muscle eQTL omic data for FTD and is it functionally significant? | There are no SNPs within the gene ANGPTL2 in Skeletal Muscle eQTL omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ANGPTL2" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%skeletal muscle eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1354684', 'topRSID': 'rs56385978', 'Disease': 'FTD', 'Gene': 'ANGPTL2', 'p_SMR_multi': 0.5201169, 'p_HEIDI': 0.4857102, 'Omic_tissue': 'Skeletal Muscle', 'Omic_type': 'Skeletal Muscle eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.206 | Q67 | What is the top-associated SNP of the gene ARHGAP45 in Cortex eQTL metaBrain omic data for AD and is it functionally significant? | The top-associated SNP for ARHGAP45 in Cortex eQTL metaBrain omic data for AD is rs117187726, which has a multi-SNP SMR p-value of 6.67e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARHGAP45" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%cortex eqtl metabrain%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1107633', 'topRSID': 'rs117187726', 'Disease': 'AD', 'Gene': 'ARHGAP45', 'p_SMR_multi': 6.667181e-09, 'p_HEIDI': 5.398231e-05, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL metaBrain', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1571 | Q67 | What is the top-associated SNP of the gene GAK in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for GAK in Whole Brain meta-analysis mQTL omic data for PD is rs17165130, which has a multi-SNP SMR p-value of 1.43e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "GAK" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_429832', 'topRSID': 'rs11248057', 'Disease': 'PD', 'Gene': 'GAK', 'p_SMR_multi': 1.488653e-10, 'p_HEIDI': 1.165356e-06, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1641 | Q67 | What is the top-associated SNP of the gene ETFDH in Hypothalamus eQTL omic data for FTD and is it functionally significant? | There are no SNPs within the gene ETFDH in Hypothalamus eQTL omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ETFDH" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%hypothalamus eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1457485', 'topRSID': 'rs28735792', 'Disease': 'FTD', 'Gene': 'ETFDH', 'p_SMR_multi': 0.5660271, 'p_HEIDI': 0.9232718, 'Omic_tissue': 'Hypothalamus', 'Omic_type': 'Hypothalamus eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1565 | Q67 | What is the top-associated SNP of the gene NPIPB9 in Cerebellum eQTL omic data for PSP and is it functionally significant? | There are no SNPs within the gene NPIPB9 in Cerebellum eQTL omic data that are significantly associated with PSP, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "NPIPB9" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_23740', 'topRSID': 'rs2650492', 'Disease': 'PSP', 'Gene': 'NPIPB9', 'p_SMR_multi': 0.9202215, 'p_HEIDI': 0.7559486, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.491 | Q67 | What is the top-associated SNP of the gene PM20D1 in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for PM20D1 in Whole Blood mQTL omic data for PD is rs1772143, which has a multi-SNP SMR p-value of 8.38e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PM20D1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_944692', 'topRSID': 'rs823080', 'Disease': 'PD', 'Gene': 'PM20D1', 'p_SMR_multi': 7.078994e-07, 'p_HEIDI': 1.577211e-06, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1966 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Blood eQTL eQTLgen omic data for PSP and is it functionally significant? | The top-associated SNP for MAPT in Whole Blood eQTL eQTLgen omic data for PSP is rs17692129, which has a multi-SNP SMR p-value of 2.30e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1579420', 'topRSID': 'rs17692129', 'Disease': 'PSP', 'Gene': 'MAPT', 'p_SMR_multi': 2.304864e-07, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1800 | Q67 | What is the top-associated SNP of the gene HCG9 in Whole Blood mQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene HCG9 in Whole Blood mQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "HCG9" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_683269', 'topRSID': 'rs114832360', 'Disease': 'ALS', 'Gene': 'HCG9', 'p_SMR_multi': 0.1247616, 'p_HEIDI': 0.8467235, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_683259', 'topR... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1330 | Q67 | What is the top-associated SNP of the gene RP11-707O23.5 in Nucleus Accumbens Basal Ganglia omic data for PSP and is it functionally significant? | The top-associated SNP for RP11-707O23.5 in Nucleus Accumbens Basal Ganglia omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 1.47e-17 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-707O23.5" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%nucleus accumbens basal ganglia%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1732392', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'RP11-707O23.5', 'p_SMR_multi': 1.4675170000000006e-17, 'p_HEIDI': 3.828291e-17, 'Omic_tissue': 'Nucleus Accumbens Basal', 'Omic_type': 'Nucleus Accumbens Basal Ganglia', 'func_sig': 'association meets significance thre... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.285 | Q67 | What is the top-associated SNP of the gene NOTCH4 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for NOTCH4 in Whole Blood mQTL omic data for AD is rs9271619, which has a multi-SNP SMR p-value of 3.74e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "NOTCH4" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_621620', 'topRSID': 'rs34562262', 'Disease': 'AD', 'Gene': 'NOTCH4', 'p_SMR_multi': 1.292283e-07, 'p_HEIDI': 0.003108897, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dise... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1375 | Q67 | What is the top-associated SNP of the gene RP11-707O23.5 in Substantia nigra eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for RP11-707O23.5 in Substantia nigra eQTL omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 1.82e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-707O23.5" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%substantia nigra eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1452480', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'RP11-707O23.5', 'p_SMR_multi': 1.822416e-09, 'p_HEIDI': 0.0024651, 'Omic_tissue': 'Substantia nigra', 'Omic_type': 'Substantia nigra eQTL', 'func_sig': 'association meets significance threshold but shows signs of linka... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.221 | Q67 | What is the top-associated SNP of the gene KLHL7-AS1 in Whole Brain eQTL omic data for PD and is it functionally significant? | The top-associated SNP for KLHL7-AS1 in Whole Brain eQTL omic data for PD is rs2072368, which has a multi-SNP SMR p-value of 4.72e-08 and a HEIDI of 0.02, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KLHL7-AS1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1636963', 'topRSID': 'rs2072368', 'Disease': 'PD', 'Gene': 'KLHL7-AS1', 'p_SMR_multi': 4.715535e-08, 'p_HEIDI': 0.01512215, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1931 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for MAPT in Whole Blood mQTL omic data for PD is rs112995313, which has a multi-SNP SMR p-value of 2.08e-10 and a HEIDI of 0.12, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_948891', 'topRSID': 'rs62063271', 'Disease': 'PD', 'Gene': 'MAPT', 'p_SMR_multi': 6.382411e-15, 'p_HEIDI': 2.368028e-06, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.888 | Q67 | What is the top-associated SNP of the gene MAPT-AS1 in Whole Brain meta-analysis mQTL omic data for PSP and is it functionally significant? | The top-associated SNP for MAPT-AS1 in Whole Brain meta-analysis mQTL omic data for PSP is rs12373139, which has a multi-SNP SMR p-value of 1.96e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT-AS1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_560854', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'MAPT-AS1', 'p_SMR_multi': 1.544458e-18, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1623 | Q67 | What is the top-associated SNP of the gene GPNMB in Whole Blood eQTL eQTLgen omic data for PD and is it functionally significant? | The top-associated SNP for GPNMB in Whole Blood eQTL eQTLgen omic data for PD is rs858239, which has a multi-SNP SMR p-value of 1.94e-08 and a HEIDI of 0.29, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "GPNMB" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1557764', 'topRSID': 'rs858239', 'Disease': 'PD', 'Gene': 'GPNMB', 'p_SMR_multi': 1.937936e-08, 'p_HEIDI': 0.2888536, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.701 | Q67 | What is the top-associated SNP of the gene KANSL1 in Whole Blood mQTL omic data for PSP and is it functionally significant? | The top-associated SNP for KANSL1 in Whole Blood mQTL omic data for PSP is rs2074404, which has a multi-SNP SMR p-value of 1.18e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1041761', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'KANSL1', 'p_SMR_multi': 3.489683e-40, 'p_HEIDI': 3.497522e-13, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dis... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.61 | Q67 | What is the top-associated SNP of the gene LRRC37A in Spinalcord eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for LRRC37A in Spinalcord eQTL omic data for PSP is rs8070723, which has a multi-SNP SMR p-value of 2.85e-11 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%spinalcord eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_30482', 'topRSID': 'rs8070723', 'Disease': 'PSP', 'Gene': 'LRRC37A', 'p_SMR_multi': 2.846173e-11, 'p_HEIDI': 1.360096e-06, 'Omic_tissue': 'Spinalcord', 'Omic_type': 'Spinalcord eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.843 | Q67 | What is the top-associated SNP of the gene CRHR1-IT1 in Whole Brain eQTL omic data for PD and is it functionally significant? | The top-associated SNP for CRHR1-IT1 in Whole Brain eQTL omic data for PD is rs62057067, which has a multi-SNP SMR p-value of 1.99e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CRHR1-IT1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1640219', 'topRSID': 'rs62057067', 'Disease': 'PD', 'Gene': 'CRHR1-IT1', 'p_SMR_multi': 1.992962e-09, 'p_HEIDI': 6.349835e-05, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1356 | Q67 | What is the top-associated SNP of the gene ARL17A in Anterior Cingulate Cortex BA24 eQTL omic data for PD and is it functionally significant? | The top-associated SNP for ARL17A in Anterior Cingulate Cortex BA24 eQTL omic data for PD is rs393152, which has a multi-SNP SMR p-value of 1.99e-08 and a HEIDI of 0.93, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARL17A" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%anterior cingulate cortex ba24 eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1488148', 'topRSID': 'rs393152', 'Disease': 'PD', 'Gene': 'ARL17A', 'p_SMR_multi': 1.985285e-08, 'p_HEIDI': 0.9268638, 'Omic_tissue': 'Anterior Cingulate Cortex BA24', 'Omic_type': 'Anterior Cingulate Cortex BA24 eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.76 | Q67 | What is the top-associated SNP of the gene PAPSS2 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | There are no SNPs within the gene PAPSS2 in Whole Blood eQTL eQTLgen omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PAPSS2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1497646', 'topRSID': 'rs1555434', 'Disease': 'AD', 'Gene': 'PAPSS2', 'p_SMR_multi': 0.2651402, 'p_HEIDI': 0.2821033, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.165 | Q67 | What is the top-associated SNP of the gene TAS2R60 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for TAS2R60 in Whole Blood eQTL eQTLgen omic data for AD is rs11771145, which has a multi-SNP SMR p-value of 1.52e-09 and a HEIDI of 0.24, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TAS2R60" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1496072', 'topRSID': 'rs11771145', 'Disease': 'AD', 'Gene': 'TAS2R60', 'p_SMR_multi': 1.519833e-09, 'p_HEIDI': 0.2381783, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.576 | Q67 | What is the top-associated SNP of the gene ZSCAN21 in Whole Brain eQTL omic data for AD and is it functionally significant? | The top-associated SNP for ZSCAN21 in Whole Brain eQTL omic data for AD is rs4729571, which has a multi-SNP SMR p-value of 7.62e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ZSCAN21" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1607806', 'topRSID': 'rs4729571', 'Disease': 'AD', 'Gene': 'ZSCAN21', 'p_SMR_multi': 7.620659e-08, 'p_HEIDI': 3.595893e-08, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Di... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.959 | Q67 | What is the top-associated SNP of the gene RP11-685N10.1 in Liver eQTL omic data for PD and is it functionally significant? | There are no SNPs within the gene RP11-685N10.1 in Liver eQTL omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-685N10.1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%liver eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1475852', 'topRSID': 'rs530569', 'Disease': 'PD', 'Gene': 'RP11-685N10.1', 'p_SMR_multi': 0.09113102, 'p_HEIDI': 0.03912808, 'Omic_tissue': 'Liver', 'Omic_type': 'Liver eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1540 | Q67 | What is the top-associated SNP of the gene HSD17B1 in Tibial Nerve eQTL omic data for PSP and is it functionally significant? | There are no SNPs within the gene HSD17B1 in Tibial Nerve eQTL omic data that are significantly associated with PSP, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "HSD17B1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%tibial nerve eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1336261', 'topRSID': 'rs1553469', 'Disease': 'PSP', 'Gene': 'HSD17B1', 'p_SMR_multi': 0.07580301, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Tibial Nerve', 'Omic_type': 'Tibial Nerve eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1046 | Q67 | What is the top-associated SNP of the gene PSORS1C1 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for PSORS1C1 in Whole Blood mQTL omic data for AD is rs3131003, which has a multi-SNP SMR p-value of 2.27e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PSORS1C1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_620729', 'topRSID': 'rs9501055', 'Disease': 'AD', 'Gene': 'PSORS1C1', 'p_SMR_multi': 5.485384e-08, 'p_HEIDI': 0.004858996, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dis... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1706 | Q67 | What is the top-associated SNP of the gene CCR10 in Whole Blood mQTL omic data for LBD and is it functionally significant? | There are no SNPs within the gene CCR10 in Whole Blood mQTL omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CCR10" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_889158', 'topRSID': 'rs9284362', 'Disease': 'LBD', 'Gene': 'CCR10', 'p_SMR_multi': 0.185996, 'p_HEIDI': 0.66034, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_889159', 'topRSID'... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.513 | Q67 | What is the top-associated SNP of the gene KANSL1 in Cerebellum eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for KANSL1 in Cerebellum eQTL omic data for PSP is rs17692129, which has a multi-SNP SMR p-value of 1.34e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_22217', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'KANSL1', 'p_SMR_multi': 9.962522e-20, 'p_HEIDI': 7.195813e-09, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequi... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.46 | Q67 | What is the top-associated SNP of the gene RNF40 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for PD and is it functionally significant? | The top-associated SNP for RNF40 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for PD is rs28853644, which has a multi-SNP SMR p-value of 1.33e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RNF40" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1435339', 'topRSID': 'rs28853644', 'Disease': 'PD', 'Gene': 'RNF40', 'p_SMR_multi': 1.331406e-06, 'p_HEIDI': 0.000260919, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'association meets significance thresh... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.946 | Q67 | What is the top-associated SNP of the gene EPHA1-AS1 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for EPHA1-AS1 in Whole Blood mQTL omic data for AD is rs1404650, which has a multi-SNP SMR p-value of 2.03e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "EPHA1-AS1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_587067', 'topRSID': 'rs75045569', 'Disease': 'AD', 'Gene': 'EPHA1-AS1', 'p_SMR_multi': 6.942181e-09, 'p_HEIDI': 0.1635299, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_587068', 'to... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.366 | Q67 | What is the top-associated SNP of the gene PXT1 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | There are no SNPs within the gene PXT1 in Whole Brain meta-analysis mQTL omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PXT1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_66833', 'topRSID': 'rs4140593', 'Disease': 'AD', 'Gene': 'PXT1', 'p_SMR_multi': 0.03340389, 'p_HEIDI': 0.2927227, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_668... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.540 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for MAPT in Whole Brain meta-analysis mQTL omic data for PD is rs17652121, which has a multi-SNP SMR p-value of 4.73e-14 and a HEIDI of 0.04, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_491114', 'topRSID': 'rs17652121', 'Disease': 'PD', 'Gene': 'MAPT', 'p_SMR_multi': 4.729064e-14, 'p_HEIDI': 0.04416005, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_49... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.79 | Q67 | What is the top-associated SNP of the gene KLHL7-AS1 in Anterior Cingulate Cortex BA24 eQTL omic data for PD and is it functionally significant? | The top-associated SNP for KLHL7-AS1 in Anterior Cingulate Cortex BA24 eQTL omic data for PD is rs6978827, which has a multi-SNP SMR p-value of 8.04e-07 and a HEIDI of 0.03, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KLHL7-AS1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%anterior cingulate cortex ba24 eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1487262', 'topRSID': 'rs6978827', 'Disease': 'PD', 'Gene': 'KLHL7-AS1', 'p_SMR_multi': 8.037308e-07, 'p_HEIDI': 0.02877158, 'Omic_tissue': 'Anterior Cingulate Cortex BA24', 'Omic_type': 'Anterior Cingulate Cortex BA24 eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1917 | Q67 | What is the top-associated SNP of the gene ESD in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | There are no SNPs within the gene ESD in Whole Brain meta-analysis mQTL omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ESD" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_99833', 'topRSID': 'rs1923880', 'Disease': 'AD', 'Gene': 'ESD', 'p_SMR_multi': 0.3738622, 'p_HEIDI': 0.3423331, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_99834... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1416 | Q67 | What is the top-associated SNP of the gene EPHX2 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for EPHX2 in Whole Brain meta-analysis mQTL omic data for AD is rs10104713, which has a multi-SNP SMR p-value of 7.48e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "EPHX2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_78248', 'topRSID': 'rs73227337', 'Disease': 'AD', 'Gene': 'EPHX2', 'p_SMR_multi': 1.500668e-09, 'p_HEIDI': 0.01595741, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_78... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.586 | Q67 | What is the top-associated SNP of the gene TSPAN13 in Whole Blood eQTL eQTLgen omic data for PSP and is it functionally significant? | There are no SNPs within the gene TSPAN13 in Whole Blood eQTL eQTLgen omic data that are significantly associated with PSP, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TSPAN13" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1572942', 'topRSID': 'rs1674809', 'Disease': 'PSP', 'Gene': 'TSPAN13', 'p_SMR_multi': 0.3490522, 'p_HEIDI': 0.9183235, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1795 | Q67 | What is the top-associated SNP of the gene RIMBP2 in Whole Blood mQTL omic data for FTD and is it functionally significant? | There are no SNPs within the gene RIMBP2 in Whole Blood mQTL omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RIMBP2" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_789799', 'topRSID': 'rs1011347', 'Disease': 'FTD', 'Gene': 'RIMBP2', 'p_SMR_multi': 0.03071137, 'p_HEIDI': 0.9718316, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_789797', 'top... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.771 | Q67 | What is the top-associated SNP of the gene SLC44A4 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for SLC44A4 in Whole Blood mQTL omic data for AD is rs2242664, which has a multi-SNP SMR p-value of 9.27e-08 and a HEIDI of 0.2, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SLC44A4" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_621257', 'topRSID': 'rs2242664', 'Disease': 'AD', 'Gene': 'SLC44A4', 'p_SMR_multi': 9.265856e-08, 'p_HEIDI': 0.2009325, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_621277', 'topRS... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.371 | Q67 | What is the top-associated SNP of the gene ZBTB38 in Whole Brain meta-analysis mQTL omic data for PSP and is it functionally significant? | There are no SNPs within the gene ZBTB38 in Whole Brain meta-analysis mQTL omic data that are significantly associated with PSP, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ZBTB38" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_518142', 'topRSID': 'rs9846396', 'Disease': 'PSP', 'Gene': 'ZBTB38', 'p_SMR_multi': 0.18821, 'p_HEIDI': 0.6856013, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_51... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.809 | Q67 | What is the top-associated SNP of the gene DGKQ in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for DGKQ in Whole Brain meta-analysis mQTL omic data for PD is rs11724804, which has a multi-SNP SMR p-value of 1.79e-08 and a HEIDI of 0.34, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "DGKQ" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_429854', 'topRSID': 'rs11724804', 'Disease': 'PD', 'Gene': 'DGKQ', 'p_SMR_multi': 1.790406e-08, 'p_HEIDI': 0.3394267, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_429... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.31 | Q67 | What is the top-associated SNP of the gene KLHL7-AS1 in Putamen Basal Ganglia eQTL omic data for PD and is it functionally significant? | The top-associated SNP for KLHL7-AS1 in Putamen Basal Ganglia eQTL omic data for PD is rs6978827, which has a multi-SNP SMR p-value of 4.56e-07 and a HEIDI of 0.02, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KLHL7-AS1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%putamen basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1593743', 'topRSID': 'rs6978827', 'Disease': 'PD', 'Gene': 'KLHL7-AS1', 'p_SMR_multi': 4.560893e-07, 'p_HEIDI': 0.02141936, 'Omic_tissue': 'Putamen Basal Ganglia', 'Omic_type': 'Putamen Basal Ganglia eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1960 | Q67 | What is the top-associated SNP of the gene NSFP1 in Skeletal Muscle eQTL omic data for PD and is it functionally significant? | The top-associated SNP for NSFP1 in Skeletal Muscle eQTL omic data for PD is rs3874943, which has a multi-SNP SMR p-value of 1.81e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "NSFP1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%skeletal muscle eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1370551', 'topRSID': 'rs3874943', 'Disease': 'PD', 'Gene': 'NSFP1', 'p_SMR_multi': 1.814056e-06, 'p_HEIDI': 2.545892e-11, 'Omic_tissue': 'Skeletal Muscle', 'Omic_type': 'Skeletal Muscle eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Link... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1742 | Q67 | What is the top-associated SNP of the gene BIN1 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for BIN1 in Whole Blood mQTL omic data for AD is rs6720234, which has a multi-SNP SMR p-value of 5.82e-18 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "BIN1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_631119', 'topRSID': 'rs58402148', 'Disease': 'AD', 'Gene': 'BIN1', 'p_SMR_multi': 2.405281e-31, 'p_HEIDI': 3.999879e-37, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1577 | Q67 | What is the top-associated SNP of the gene ARL17B in Skeletal Muscle eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for ARL17B in Skeletal Muscle eQTL omic data for PSP is rs4792831, which has a multi-SNP SMR p-value of 1.34e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARL17B" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%skeletal muscle eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1375933', 'topRSID': 'rs4792831', 'Disease': 'PSP', 'Gene': 'ARL17B', 'p_SMR_multi': 1.338852e-09, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Skeletal Muscle', 'Omic_type': 'Skeletal Muscle eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.794 | Q67 | What is the top-associated SNP of the gene WNT3 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for WNT3 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for PSP is rs8069437, which has a multi-SNP SMR p-value of 4.41e-13 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "WNT3" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1444278', 'topRSID': 'rs8069437', 'Disease': 'PSP', 'Gene': 'WNT3', 'p_SMR_multi': 4.410459e-13, 'p_HEIDI': 5.247729e-09, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'association meets significance thresh... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1249 | Q67 | What is the top-associated SNP of the gene AMOTL2 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | There are no SNPs within the gene AMOTL2 in Whole Brain meta-analysis mQTL omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "AMOTL2" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_428172', 'topRSID': 'rs1466827', 'Disease': 'PD', 'Gene': 'AMOTL2', 'p_SMR_multi': 0.2884974, 'p_HEIDI': 0.1676187, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_4... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.501 | Q67 | What is the top-associated SNP of the gene RP11-259G18.3 in Caudate Basal Ganglia eQTL omic data for PD and is it functionally significant? | The top-associated SNP for RP11-259G18.3 in Caudate Basal Ganglia eQTL omic data for PD is rs55974014, which has a multi-SNP SMR p-value of 1.39e-12 and a HEIDI of 0.22, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.3" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%caudate basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1281357', 'topRSID': 'rs55974014', 'Disease': 'PD', 'Gene': 'RP11-259G18.3', 'p_SMR_multi': 1.387203e-12, 'p_HEIDI': 0.2207953, 'Omic_tissue': 'Caudate Basal Ganglia', 'Omic_type': 'Caudate Basal Ganglia eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1551 | Q67 | What is the top-associated SNP of the gene RP11-798G7.6 in Whole Blood eQTL GTEx omic data for PD and is it functionally significant? | The top-associated SNP for RP11-798G7.6 in Whole Blood eQTL GTEx omic data for PD is rs11656151, which has a multi-SNP SMR p-value of 6.28e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-798G7.6" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1679561', 'topRSID': 'rs11656151', 'Disease': 'PD', 'Gene': 'RP11-798G7.6', 'p_SMR_multi': 6.279704e-07, 'p_HEIDI': 0.002230586, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL GTEx', 'func_sig': 'association meets significance threshold but shows signs of linkage/ ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1568 | Q67 | What is the top-associated SNP of the gene PANX2 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | There are no SNPs within the gene PANX2 in Whole Brain meta-analysis mQTL omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PANX2" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_504904', 'topRSID': 'rs4838859', 'Disease': 'PD', 'Gene': 'PANX2', 'p_SMR_multi': 0.01689137, 'p_HEIDI': 0.2484109, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_5... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.991 | Q67 | What is the top-associated SNP of the gene SLC6A1 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | There are no SNPs within the gene SLC6A1 in Whole Brain meta-analysis mQTL omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SLC6A1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_49689', 'topRSID': 'rs2697148', 'Disease': 'AD', 'Gene': 'SLC6A1', 'p_SMR_multi': 0.2064161, 'p_HEIDI': 0.6631458, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_49... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1574 | Q67 | What is the top-associated SNP of the gene CLPTM1 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD and is it functionally significant? | The top-associated SNP for CLPTM1 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD is rs10422888, which has a multi-SNP SMR p-value of 1.39e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CLPTM1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1397648', 'topRSID': 'rs10422888', 'Disease': 'AD', 'Gene': 'CLPTM1', 'p_SMR_multi': 1.38944e-08, 'p_HEIDI': 1.169438e-08, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'association meets significance thres... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.45 | Q67 | What is the top-associated SNP of the gene RP11-259G18.1 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for RP11-259G18.1 in Whole Brain meta-analysis mQTL omic data for PD is rs111198951, which has a multi-SNP SMR p-value of 5.73e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_491164', 'topRSID': 'rs554899842', 'Disease': 'PD', 'Gene': 'RP11-259G18.1', 'p_SMR_multi': 5.604857e-13, 'p_HEIDI': 0.01086052, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_upda... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1608 | Q67 | What is the top-associated SNP of the gene NUPL2 in Frontal Cortex BA9 eQTL omic data for PD and is it functionally significant? | The top-associated SNP for NUPL2 in Frontal Cortex BA9 eQTL omic data for PD is rs858289, which has a multi-SNP SMR p-value of 1.34e-06 and a HEIDI of 0.97, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "NUPL2" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%frontal cortex ba9 eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1167542', 'topRSID': 'rs858289', 'Disease': 'PD', 'Gene': 'NUPL2', 'p_SMR_multi': 1.340795e-06, 'p_HEIDI': 0.9681001, 'Omic_tissue': 'Frontal Cortex', 'Omic_type': 'Frontal Cortex BA9 eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.171 | Q67 | What is the top-associated SNP of the gene IGHGP in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for IGHGP in Whole Blood eQTL eQTLgen omic data for AD is rs11627978, which has a multi-SNP SMR p-value of 2.39e-07 and a HEIDI of 0.02, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "IGHGP" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1500533', 'topRSID': 'rs11627978', 'Disease': 'AD', 'Gene': 'IGHGP', 'p_SMR_multi': 2.39192e-07, 'p_HEIDI': 0.02296792, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.307 | Q67 | What is the top-associated SNP of the gene CHRNA5 in Hypothalamus eQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene CHRNA5 in Hypothalamus eQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CHRNA5" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%hypothalamus eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1456332', 'topRSID': 'rs7164030', 'Disease': 'ALS', 'Gene': 'CHRNA5', 'p_SMR_multi': 0.268916, 'p_HEIDI': 0.9941188, 'Omic_tissue': 'Hypothalamus', 'Omic_type': 'Hypothalamus eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1957 | Q67 | What is the top-associated SNP of the gene MAPT-AS1 in Skeletal Muscle eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for MAPT-AS1 in Skeletal Muscle eQTL omic data for PSP is rs11012, which has a multi-SNP SMR p-value of 2.76e-11 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT-AS1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%skeletal muscle eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1375928', 'topRSID': 'rs11012', 'Disease': 'PSP', 'Gene': 'MAPT-AS1', 'p_SMR_multi': 2.764951e-11, 'p_HEIDI': 0.00244082, 'Omic_tissue': 'Skeletal Muscle', 'Omic_type': 'Skeletal Muscle eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Link... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1105 | Q67 | What is the top-associated SNP of the gene DNMT3A in Whole Brain meta-analysis mQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene DNMT3A in Whole Brain meta-analysis mQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "DNMT3A" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_139518', 'topRSID': 'rs7581217', 'Disease': 'ALS', 'Gene': 'DNMT3A', 'p_SMR_multi': 0.06879074, 'p_HEIDI': 0.08408941, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_tex... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1925 | Q67 | What is the top-associated SNP of the gene PILRA in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for PILRA in Whole Blood eQTL eQTLgen omic data for AD is rs2005763, which has a multi-SNP SMR p-value of 2.30e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PILRA" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1495807', 'topRSID': 'rs2005763', 'Disease': 'AD', 'Gene': 'PILRA', 'p_SMR_multi': 2.304559e-09, 'p_HEIDI': 6.915895e-05, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Link... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1038 | Q67 | What is the top-associated SNP of the gene INO80E in Whole Brain eQTL omic data for AD and is it functionally significant? | The top-associated SNP for INO80E in Whole Brain eQTL omic data for AD is rs10871451, which has a multi-SNP SMR p-value of 5.07e-08 and a HEIDI of 0.47, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "INO80E" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1610394', 'topRSID': 'rs10871451', 'Disease': 'AD', 'Gene': 'INO80E', 'p_SMR_multi': 5.074467e-08, 'p_HEIDI': 0.4675354, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.658 | Q67 | What is the top-associated SNP of the gene RP11-707O23.5 in Hypothalamus eQTL omic data for PD and is it functionally significant? | The top-associated SNP for RP11-707O23.5 in Hypothalamus eQTL omic data for PD is rs55974014, which has a multi-SNP SMR p-value of 1.27e-11 and a HEIDI of 0.85, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-707O23.5" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%hypothalamus eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1462891', 'topRSID': 'rs55974014', 'Disease': 'PD', 'Gene': 'RP11-707O23.5', 'p_SMR_multi': 1.274776e-11, 'p_HEIDI': 0.8530115, 'Omic_tissue': 'Hypothalamus', 'Omic_type': 'Hypothalamus eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.373 | Q67 | What is the top-associated SNP of the gene CLPTM1 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for CLPTM1 in Whole Blood mQTL omic data for AD is rs12460352, which has a multi-SNP SMR p-value of 1.52e-15 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CLPTM1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_637440', 'topRSID': 'rs2239375', 'Disease': 'AD', 'Gene': 'CLPTM1', 'p_SMR_multi': 2.260011e-27, 'p_HEIDI': 1.039963e-13, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dise... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1661 | Q67 | What is the top-associated SNP of the gene KANSL1 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for KANSL1 in Whole Brain meta-analysis mQTL omic data for PD is rs8712, which has a multi-SNP SMR p-value of 1.36e-10 and a HEIDI of 0.02, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_491139', 'topRSID': 'rs12150087', 'Disease': 'PD', 'Gene': 'KANSL1', 'p_SMR_multi': 8.107128999999999e-20, 'p_HEIDI': 0.009069932, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs o... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1513 | Q67 | What is the top-associated SNP of the gene CD38 in Prefrontal Cortex eQTL omic data for PD and is it functionally significant? | The top-associated SNP for CD38 in Prefrontal Cortex eQTL omic data for PD is rs11724635, which has a multi-SNP SMR p-value of 3.93e-10 and a HEIDI of 0.91, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CD38" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%prefrontal cortex eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1236251', 'topRSID': 'rs11724635', 'Disease': 'PD', 'Gene': 'CD38', 'p_SMR_multi': 3.931599e-10, 'p_HEIDI': 0.9101781, 'Omic_tissue': 'Prefrontal Cortex', 'Omic_type': 'Prefrontal Cortex eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.778 | Q67 | What is the top-associated SNP of the gene RP11-259G18.3 in Skeletal Muscle eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for RP11-259G18.3 in Skeletal Muscle eQTL omic data for PSP is rs169201, which has a multi-SNP SMR p-value of 2.64e-33 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.3" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%skeletal muscle eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1375931', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'RP11-259G18.3', 'p_SMR_multi': 2.638097e-33, 'p_HEIDI': 1.529365e-13, 'Omic_tissue': 'Skeletal Muscle', 'Omic_type': 'Skeletal Muscle eQTL', 'func_sig': 'association meets significance threshold but shows signs of linka... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.328 | Q67 | What is the top-associated SNP of the gene CTB-39G8.3 in Whole Blood eQTL GTEx omic data for PSP and is it functionally significant? | The top-associated SNP for CTB-39G8.3 in Whole Blood eQTL GTEx omic data for PSP is rs1230103, which has a multi-SNP SMR p-value of 1.32e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CTB-39G8.3" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1684927', 'topRSID': 'rs1230103', 'Disease': 'PSP', 'Gene': 'CTB-39G8.3', 'p_SMR_multi': 1.318334e-06, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL GTEx', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkag... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1988 | Q67 | What is the top-associated SNP of the gene RP11-443P15.2 in Whole Brain meta-analysis mQTL omic data for FTD and is it functionally significant? | There are no SNPs within the gene RP11-443P15.2 in Whole Brain meta-analysis mQTL omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-443P15.2" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_244241', 'topRSID': 'rs9290827', 'Disease': 'FTD', 'Gene': 'RP11-443P15.2', 'p_SMR_multi': 0.2565654, 'p_HEIDI': 0.7419438, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_updat... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1924 | Q67 | What is the top-associated SNP of the gene CTD-2619J13.19 in Whole Brain eQTL omic data for AD and is it functionally significant? | There are no SNPs within the gene CTD-2619J13.19 in Whole Brain eQTL omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CTD-2619J13.19" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1611727', 'topRSID': 'rs4801585', 'Disease': 'AD', 'Gene': 'CTD-2619J13.19', 'p_SMR_multi': 0.02915823, 'p_HEIDI': 0.4516223, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.931 | Q67 | What is the top-associated SNP of the gene ABCA7 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for ABCA7 in Whole Blood mQTL omic data for AD is rs2020000, which has a multi-SNP SMR p-value of 1.32e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ABCA7" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_634279', 'topRSID': 'rs3764642', 'Disease': 'AD', 'Gene': 'ABCA7', 'p_SMR_multi': 2.490416e-10, 'p_HEIDI': 0.0002263415, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.188 | Q67 | What is the top-associated SNP of the gene GRN in Cortex eQTL metaBrain omic data for AD and is it functionally significant? | The top-associated SNP for GRN in Cortex eQTL metaBrain omic data for AD is rs5848, which has a multi-SNP SMR p-value of 4.47e-07 and a HEIDI of 0.43, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "GRN" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%cortex eqtl metabrain%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1106816', 'topRSID': 'rs5848', 'Disease': 'AD', 'Gene': 'GRN', 'p_SMR_multi': 4.468436e-07, 'p_HEIDI': 0.4339071, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL metaBrain', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1595 | Q67 | What is the top-associated SNP of the gene KANSL1 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for KANSL1 in Whole Brain meta-analysis mQTL omic data for PD is rs2668665, which has a multi-SNP SMR p-value of 6.88e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_491139', 'topRSID': 'rs12150087', 'Disease': 'PD', 'Gene': 'KANSL1', 'p_SMR_multi': 8.107128999999999e-20, 'p_HEIDI': 0.009069932, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs o... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.772 | Q67 | What is the top-associated SNP of the gene GPC2 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for GPC2 in Whole Brain meta-analysis mQTL omic data for AD is rs6465765, which has a multi-SNP SMR p-value of 1.98e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "GPC2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_74045', 'topRSID': 'rs866500', 'Disease': 'AD', 'Gene': 'GPC2', 'p_SMR_multi': 6.77721e-09, 'p_HEIDI': 5.570468e-05, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Lin... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1203 | Q67 | What is the top-associated SNP of the gene FAM215B in Cerebellar Hemisphere eQTL omic data for PD and is it functionally significant? | The top-associated SNP for FAM215B in Cerebellar Hemisphere eQTL omic data for PD is rs9896243, which has a multi-SNP SMR p-value of 8.12e-09 and a HEIDI of 0.06, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "FAM215B" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cerebellar hemisphere eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1191181', 'topRSID': 'rs9896243', 'Disease': 'PD', 'Gene': 'FAM215B', 'p_SMR_multi': 8.116734e-09, 'p_HEIDI': 0.06161497, 'Omic_tissue': 'Cerebellar Hemisphere', 'Omic_type': 'Cerebellar Hemisphere eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.500 | Q67 | What is the top-associated SNP of the gene RP11-134D3.2 in Whole Brain meta-analysis mQTL omic data for LBD and is it functionally significant? | There are no SNPs within the gene RP11-134D3.2 in Whole Brain meta-analysis mQTL omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-134D3.2" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_392129', 'topRSID': 'rs11646482', 'Disease': 'LBD', 'Gene': 'RP11-134D3.2', 'p_SMR_multi': 0.1811687, 'p_HEIDI': 0.2204227, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_updat... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1064 | Q67 | What is the top-associated SNP of the gene KANSL1 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for KANSL1 in Whole Brain meta-analysis mQTL omic data for PD is rs12150087, which has a multi-SNP SMR p-value of 8.11e-20 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_491139', 'topRSID': 'rs12150087', 'Disease': 'PD', 'Gene': 'KANSL1', 'p_SMR_multi': 8.107128999999999e-20, 'p_HEIDI': 0.009069932, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs o... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1111 | Q67 | What is the top-associated SNP of the gene LRRC37A in Cortex eQTL GTEx omic data for PSP and is it functionally significant? | The top-associated SNP for LRRC37A in Cortex eQTL GTEx omic data for PSP is rs7225002, which has a multi-SNP SMR p-value of 1.70e-12 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%cortex eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1264987', 'topRSID': 'rs7225002', 'Disease': 'PSP', 'Gene': 'LRRC37A', 'p_SMR_multi': 1.701597e-12, 'p_HEIDI': 2.216584e-11, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL GTEx', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.536 | Q67 | What is the top-associated SNP of the gene ADAM10 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for ADAM10 in Whole Brain meta-analysis mQTL omic data for AD is rs2250583, which has a multi-SNP SMR p-value of 2.60e-06 and a HEIDI of 0.08, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ADAM10" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_105563', 'topRSID': 'rs2250583', 'Disease': 'AD', 'Gene': 'ADAM10', 'p_SMR_multi': 2.600605e-06, 'p_HEIDI': 0.07790174, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1601 | Q67 | What is the top-associated SNP of the gene LILRA3 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for LILRA3 in Whole Blood eQTL eQTLgen omic data for AD is rs367070, which has a multi-SNP SMR p-value of 1.33e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LILRA3" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1504180', 'topRSID': 'rs367070', 'Disease': 'AD', 'Gene': 'LILRA3', 'p_SMR_multi': 1.334091e-06, 'p_HEIDI': 0.0003023186, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Link... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.752 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Brain meta-analysis mQTL omic data for PSP and is it functionally significant? | The top-associated SNP for MAPT in Whole Brain meta-analysis mQTL omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 1.77e-14 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_560864', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'MAPT', 'p_SMR_multi': 2.100115e-44, 'p_HEIDI': 0.01425494, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_56... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1933 | Q67 | What is the top-associated SNP of the gene PARD3 in Whole Blood eQTL eQTLgen omic data for LBD and is it functionally significant? | There are no SNPs within the gene PARD3 in Whole Blood eQTL eQTLgen omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PARD3" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1544234', 'topRSID': 'rs11009923', 'Disease': 'LBD', 'Gene': 'PARD3', 'p_SMR_multi': 0.3588437, 'p_HEIDI': 0.4822199, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1367 | Q67 | What is the top-associated SNP of the gene ABCA7 in Cerebellum eQTL omic data for AD and is it functionally significant? | The top-associated SNP for ABCA7 in Cerebellum eQTL omic data for AD is rs10419707, which has a multi-SNP SMR p-value of 1.29e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ABCA7" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_3801', 'topRSID': 'rs10419707', 'Disease': 'AD', 'Gene': 'ABCA7', 'p_SMR_multi': 1.294237e-06, 'p_HEIDI': 3.481826e-05, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequil... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1444 | Q67 | What is the top-associated SNP of the gene LRP5L in Skeletal Muscle eQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene LRP5L in Skeletal Muscle eQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRP5L" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%skeletal muscle eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1351235', 'topRSID': 'rs11090388', 'Disease': 'ALS', 'Gene': 'LRP5L', 'p_SMR_multi': 0.649048, 'p_HEIDI': 0.8006303, 'Omic_tissue': 'Skeletal Muscle', 'Omic_type': 'Skeletal Muscle eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
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