uuid stringlengths 4 8 | template_uuid stringclasses 40
values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 133 622 | execution_results stringlengths 2 1.14M | query_type stringclasses 2
values | sql_category stringclasses 26
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|---|---|---|---|---|---|---|---|---|
Q67.1371 | Q67 | What is the top-associated SNP of the gene ZNF195 in Caudate Basal Ganglia eQTL omic data for PSP and is it functionally significant? | There are no SNPs within the gene ZNF195 in Caudate Basal Ganglia eQTL omic data that are significantly associated with PSP, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ZNF195" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%caudate basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1283159', 'topRSID': 'rs7103207', 'Disease': 'PSP', 'Gene': 'ZNF195', 'p_SMR_multi': 0.6624105, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Caudate Basal Ganglia', 'Omic_type': 'Caudate Basal Ganglia eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1171 | Q67 | What is the top-associated SNP of the gene LRRC37A2 in Hippocampus eQTL omic data for AD and is it functionally significant? | The top-associated SNP for LRRC37A2 in Hippocampus eQTL omic data for AD is rs2942166, which has a multi-SNP SMR p-value of 2.25e-06 and a HEIDI of 0.37, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%hippocampus eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1378575', 'topRSID': 'rs2942166', 'Disease': 'AD', 'Gene': 'LRRC37A2', 'p_SMR_multi': 2.251302e-06, 'p_HEIDI': 0.3720312, 'Omic_tissue': 'Hippocampus', 'Omic_type': 'Hippocampus eQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_30835', 'topR... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.138 | Q67 | What is the top-associated SNP of the gene ARHGAP27 in Whole Brain meta-analysis mQTL omic data for PSP and is it functionally significant? | The top-associated SNP for ARHGAP27 in Whole Brain meta-analysis mQTL omic data for PSP is rs11012, which has a multi-SNP SMR p-value of 2.67e-13 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARHGAP27" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_560834', 'topRSID': 'rs11012', 'Disease': 'PSP', 'Gene': 'ARHGAP27', 'p_SMR_multi': 9.282341e-28, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Li... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1134 | Q67 | What is the top-associated SNP of the gene FAM213A in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD and is it functionally significant? | The top-associated SNP for FAM213A in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD is rs4934147, which has a multi-SNP SMR p-value of 1.60e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "FAM213A" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT 10... | [{'UUID': 'NDD_SMR_genes_all_update_text_1393824', 'topRSID': 'rs4934147', 'Disease': 'AD', 'Gene': 'FAM213A', 'p_SMR_multi': 1.601714e-06, 'p_HEIDI': 1.163999e-06, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'association meets significance thre... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1874 | Q67 | What is the top-associated SNP of the gene EPHA1-AS1 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for EPHA1-AS1 in Whole Brain meta-analysis mQTL omic data for AD is rs10226151, which has a multi-SNP SMR p-value of 2.94e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "EPHA1-AS1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_75161', 'topRSID': 'rs10226151', 'Disease': 'AD', 'Gene': 'EPHA1-AS1', 'p_SMR_multi': 2.944914e-09, 'p_HEIDI': 3.247074e-05, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of link... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1241 | Q67 | What is the top-associated SNP of the gene PM20D1 in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for PM20D1 in Whole Blood mQTL omic data for PD is rs1772143, which has a multi-SNP SMR p-value of 8.76e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PM20D1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_944692', 'topRSID': 'rs823080', 'Disease': 'PD', 'Gene': 'PM20D1', 'p_SMR_multi': 7.078994e-07, 'p_HEIDI': 1.577211e-06, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1338 | Q67 | What is the top-associated SNP of the gene SH2D4B in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for SH2D4B in Whole Blood mQTL omic data for AD is rs11186258, which has a multi-SNP SMR p-value of 2.62e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SH2D4B" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_572665', 'topRSID': 'rs11186258', 'Disease': 'AD', 'Gene': 'SH2D4B', 'p_SMR_multi': 2.621326e-08, 'p_HEIDI': 0.001258736, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dise... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.958 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for MAPT in Whole Blood mQTL omic data for PD is rs62063271, which has a multi-SNP SMR p-value of 9.76e-14 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_948891', 'topRSID': 'rs62063271', 'Disease': 'PD', 'Gene': 'MAPT', 'p_SMR_multi': 6.382411e-15, 'p_HEIDI': 2.368028e-06, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.929 | Q67 | What is the top-associated SNP of the gene PDIA4 in Whole Brain eQTL omic data for PD and is it functionally significant? | There are no SNPs within the gene PDIA4 in Whole Brain eQTL omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PDIA4" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1637247', 'topRSID': 'rs11546290', 'Disease': 'PD', 'Gene': 'PDIA4', 'p_SMR_multi': 0.7892511, 'p_HEIDI': 0.6691572, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.112 | Q67 | What is the top-associated SNP of the gene HEMGN in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | There are no SNPs within the gene HEMGN in Whole Brain meta-analysis mQTL omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "HEMGN" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_457792', 'topRSID': 'rs4742708', 'Disease': 'PD', 'Gene': 'HEMGN', 'p_SMR_multi': 0.7421476, 'p_HEIDI': 0.7576957, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1240 | Q67 | What is the top-associated SNP of the gene KANSL1-AS1 in Putamen Basal Ganglia eQTL omic data for PD and is it functionally significant? | The top-associated SNP for KANSL1-AS1 in Putamen Basal Ganglia eQTL omic data for PD is rs55974014, which has a multi-SNP SMR p-value of 1.42e-12 and a HEIDI of 0.4, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1-AS1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%putamen basal ganglia eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1594924', 'topRSID': 'rs55974014', 'Disease': 'PD', 'Gene': 'KANSL1-AS1', 'p_SMR_multi': 1.416904e-12, 'p_HEIDI': 0.4024768, 'Omic_tissue': 'Putamen Basal Ganglia', 'Omic_type': 'Putamen Basal Ganglia eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1921 | Q67 | What is the top-associated SNP of the gene GSN in Whole Brain eQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene GSN in Whole Brain eQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "GSN" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%whole brain eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1615912', 'topRSID': 'rs76098787', 'Disease': 'ALS', 'Gene': 'GSN', 'p_SMR_multi': 0.9323202, 'p_HEIDI': 0.5337403, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1963 | Q67 | What is the top-associated SNP of the gene APOC4 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for APOC4 in Whole Brain meta-analysis mQTL omic data for AD is rs11878597, which has a multi-SNP SMR p-value of 1.94e-13 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "APOC4" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_122468', 'topRSID': 'rs11878597', 'Disease': 'AD', 'Gene': 'APOC4', 'p_SMR_multi': 1.942575e-13, 'p_HEIDI': 5.901231e-09, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.214 | Q67 | What is the top-associated SNP of the gene ARL17B in Cerebellum eQTL omic data for PD and is it functionally significant? | The top-associated SNP for ARL17B in Cerebellum eQTL omic data for PD is rs4510068, which has a multi-SNP SMR p-value of 1.41e-12 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARL17B" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_19649', 'topRSID': 'rs4510068', 'Disease': 'PD', 'Gene': 'ARL17B', 'p_SMR_multi': 1.412786e-12, 'p_HEIDI': 3.739719e-07, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequi... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.999 | Q67 | What is the top-associated SNP of the gene ASPHD1 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for ASPHD1 in Whole Blood mQTL omic data for AD is rs11644048, which has a multi-SNP SMR p-value of 5.82e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ASPHD1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_577410', 'topRSID': 'rs11644048', 'Disease': 'AD', 'Gene': 'ASPHD1', 'p_SMR_multi': 5.817597e-08, 'p_HEIDI': 0.0001874638, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dis... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1269 | Q67 | What is the top-associated SNP of the gene WFIKKN1 in Liver eQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene WFIKKN1 in Liver eQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "WFIKKN1" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%liver eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1468962', 'topRSID': 'rs1984395', 'Disease': 'ALS', 'Gene': 'WFIKKN1', 'p_SMR_multi': 0.009007396, 'p_HEIDI': 0.21462, 'Omic_tissue': 'Liver', 'Omic_type': 'Liver eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.592 | Q67 | What is the top-associated SNP of the gene SCFD1 in Whole Blood eQTL eQTLgen omic data for ALS and is it functionally significant? | The top-associated SNP for SCFD1 in Whole Blood eQTL eQTLgen omic data for ALS is rs7144204, which has a multi-SNP SMR p-value of 7.01e-07 and a HEIDI of 0.18, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SCFD1" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1515764', 'topRSID': 'rs7144204', 'Disease': 'ALS', 'Gene': 'SCFD1', 'p_SMR_multi': 7.008029e-07, 'p_HEIDI': 0.1817184, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1391 | Q67 | What is the top-associated SNP of the gene RP11-707O23.5 in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for RP11-707O23.5 in Whole Brain meta-analysis mQTL omic data for PD is rs440778, which has a multi-SNP SMR p-value of 6.02e-12 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-707O23.5" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_491083', 'topRSID': 'rs440778', 'Disease': 'PD', 'Gene': 'RP11-707O23.5', 'p_SMR_multi': 9.366102e-16, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkag... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1450 | Q67 | What is the top-associated SNP of the gene CELF4 in Whole Blood mQTL omic data for AD and is it functionally significant? | There are no SNPs within the gene CELF4 in Whole Blood mQTL omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CELF4" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_644838', 'topRSID': 'rs650540', 'Disease': 'AD', 'Gene': 'CELF4', 'p_SMR_multi': 0.1219306, 'p_HEIDI': 0.02976749, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_644839', 'topRSI... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.279 | Q67 | What is the top-associated SNP of the gene ZSCAN21 in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for ZSCAN21 in Whole Blood eQTL eQTLgen omic data for AD is rs55969052, which has a multi-SNP SMR p-value of 1.27e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ZSCAN21" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1495788', 'topRSID': 'rs55969052', 'Disease': 'AD', 'Gene': 'ZSCAN21', 'p_SMR_multi': 1.273647e-07, 'p_HEIDI': 2.363157e-10, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ L... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1507 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Brain meta-analysis mQTL omic data for PSP and is it functionally significant? | The top-associated SNP for MAPT in Whole Brain meta-analysis mQTL omic data for PSP is rs12373139, which has a multi-SNP SMR p-value of 6.30e-15 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_560864', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'MAPT', 'p_SMR_multi': 2.100115e-44, 'p_HEIDI': 0.01425494, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_56... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1328 | Q67 | What is the top-associated SNP of the gene TONSL in Skeletal Muscle eQTL omic data for PD and is it functionally significant? | There are no SNPs within the gene TONSL in Skeletal Muscle eQTL omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TONSL" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%skeletal muscle eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1368066', 'topRSID': 'rs10902781', 'Disease': 'PD', 'Gene': 'TONSL', 'p_SMR_multi': 0.9061847, 'p_HEIDI': 0.9143408, 'Omic_tissue': 'Skeletal Muscle', 'Omic_type': 'Skeletal Muscle eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1271 | Q67 | What is the top-associated SNP of the gene NOX4 in Hippocampus eQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene NOX4 in Hippocampus eQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "NOX4" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%hippocampus eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_31466', 'topRSID': 'rs10830357', 'Disease': 'ALS', 'Gene': 'NOX4', 'p_SMR_multi': 0.5477496, 'p_HEIDI': 0.5881458, 'Omic_tissue': 'Hippocampus', 'Omic_type': 'Hippocampus eQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_1380242', 'topRS... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1820 | Q67 | What is the top-associated SNP of the gene FCER1G in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD and is it functionally significant? | The top-associated SNP for FCER1G in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD is rs4379692, which has a multi-SNP SMR p-value of 2.89e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "FCER1G" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1389452', 'topRSID': 'rs4379692', 'Disease': 'AD', 'Gene': 'FCER1G', 'p_SMR_multi': 2.894472e-07, 'p_HEIDI': 0.005983408, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'association meets significance thresh... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.273 | Q67 | What is the top-associated SNP of the gene LRRC37A in Whole Blood eQTL GTEx omic data for PSP and is it functionally significant? | The top-associated SNP for LRRC37A in Whole Blood eQTL GTEx omic data for PSP is rs7225002, which has a multi-SNP SMR p-value of 7.52e-12 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1684939', 'topRSID': 'rs7225002', 'Disease': 'PSP', 'Gene': 'LRRC37A', 'p_SMR_multi': 7.518561e-12, 'p_HEIDI': 1.386336e-11, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL GTEx', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Link... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1863 | Q67 | What is the top-associated SNP of the gene CSGALNACT1 in Cerebellum eQTL omic data for ALS and is it functionally significant? | There are no SNPs within the gene CSGALNACT1 in Cerebellum eQTL omic data that are significantly associated with ALS, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CSGALNACT1" AND Disease = "ALS" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_7918', 'topRSID': 'rs10888163', 'Disease': 'ALS', 'Gene': 'CSGALNACT1', 'p_SMR_multi': 0.1708553, 'p_HEIDI': 0.0533924, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_1693240', 'to... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.578 | Q67 | What is the top-associated SNP of the gene LRRC37A2 in Hippocampus eQTL omic data for PD and is it functionally significant? | The top-associated SNP for LRRC37A2 in Hippocampus eQTL omic data for PD is rs2696466, which has a multi-SNP SMR p-value of 9.45e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A2" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%hippocampus eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1386997', 'topRSID': 'rs2942166', 'Disease': 'PD', 'Gene': 'LRRC37A2', 'p_SMR_multi': 1.427218e-11, 'p_HEIDI': 0.3236888, 'Omic_tissue': 'Hippocampus', 'Omic_type': 'Hippocampus eQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_33017', 'topR... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.638 | Q67 | What is the top-associated SNP of the gene LRRC37A2 in Cortex eQTL GTEx omic data for PD and is it functionally significant? | The top-associated SNP for LRRC37A2 in Cortex eQTL GTEx omic data for PD is rs56971664, which has a multi-SNP SMR p-value of 9.36e-12 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A2" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cortex eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1262232', 'topRSID': 'rs56971664', 'Disease': 'PD', 'Gene': 'LRRC37A2', 'p_SMR_multi': 9.358939e-12, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL GTEx', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequilib... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.713 | Q67 | What is the top-associated SNP of the gene LRRC37A4P in Whole Brain eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for LRRC37A4P in Whole Brain eQTL omic data for PSP is rs11012, which has a multi-SNP SMR p-value of 6.90e-33 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A4P" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole brain eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1646037', 'topRSID': 'rs11012', 'Disease': 'PSP', 'Gene': 'LRRC37A4P', 'p_SMR_multi': 6.904322e-33, 'p_HEIDI': 0.0008119001, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage D... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1529 | Q67 | What is the top-associated SNP of the gene PLA2G2A in Whole Blood mQTL omic data for LBD and is it functionally significant? | There are no SNPs within the gene PLA2G2A in Whole Blood mQTL omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PLA2G2A" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_876109', 'topRSID': 'rs55981420', 'Disease': 'LBD', 'Gene': 'PLA2G2A', 'p_SMR_multi': 0.03596105, 'p_HEIDI': 0.2027105, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_876105', 't... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.627 | Q67 | What is the top-associated SNP of the gene KANSL1 in Whole Blood mQTL omic data for PSP and is it functionally significant? | The top-associated SNP for KANSL1 in Whole Blood mQTL omic data for PSP is rs17692129, which has a multi-SNP SMR p-value of 4.58e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1041761', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'KANSL1', 'p_SMR_multi': 3.489683e-40, 'p_HEIDI': 3.497522e-13, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dis... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1991 | Q67 | What is the top-associated SNP of the gene PVRL2 in Whole Blood eQTL GTEx omic data for AD and is it functionally significant? | The top-associated SNP for PVRL2 in Whole Blood eQTL GTEx omic data for AD is rs60389450, which has a multi-SNP SMR p-value of 1.05e-17 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PVRL2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1653157', 'topRSID': 'rs60389450', 'Disease': 'AD', 'Gene': 'PVRL2', 'p_SMR_multi': 1.045403e-17, 'p_HEIDI': 2.887377e-16, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL GTEx', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkag... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.813 | Q67 | What is the top-associated SNP of the gene HSD17B7P2 in Prefrontal Cortex eQTL omic data for FTD and is it functionally significant? | There are no SNPs within the gene HSD17B7P2 in Prefrontal Cortex eQTL omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "HSD17B7P2" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%prefrontal cortex eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1219727', 'topRSID': 'rs2997787', 'Disease': 'FTD', 'Gene': 'HSD17B7P2', 'p_SMR_multi': 0.1501851, 'p_HEIDI': 0.6947979, 'Omic_tissue': 'Prefrontal Cortex', 'Omic_type': 'Prefrontal Cortex eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.309 | Q67 | What is the top-associated SNP of the gene CASTOR3 in Cortex eQTL metaBrain omic data for AD and is it functionally significant? | The top-associated SNP for CASTOR3 in Cortex eQTL metaBrain omic data for AD is rs17309333, which has a multi-SNP SMR p-value of 1.21e-06 and a HEIDI of 0.56, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CASTOR3" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%cortex eqtl metabrain%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1105974', 'topRSID': 'rs17309333', 'Disease': 'AD', 'Gene': 'CASTOR3', 'p_SMR_multi': 1.214914e-06, 'p_HEIDI': 0.5580988, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL metaBrain', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.550 | Q67 | What is the top-associated SNP of the gene SEC14L6 in Cerebellar Hemisphere eQTL omic data for LBD and is it functionally significant? | There are no SNPs within the gene SEC14L6 in Cerebellar Hemisphere eQTL omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SEC14L6" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%cerebellar hemisphere eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1187731', 'topRSID': 'rs5749123', 'Disease': 'LBD', 'Gene': 'SEC14L6', 'p_SMR_multi': 0.9265755, 'p_HEIDI': 0.6765159, 'Omic_tissue': 'Cerebellar Hemisphere', 'Omic_type': 'Cerebellar Hemisphere eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1606 | Q67 | What is the top-associated SNP of the gene AIFM2 in Whole Brain eQTL omic data for PSP and is it functionally significant? | There are no SNPs within the gene AIFM2 in Whole Brain eQTL omic data that are significantly associated with PSP, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "AIFM2" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole brain eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1644437', 'topRSID': 'rs10762345', 'Disease': 'PSP', 'Gene': 'AIFM2', 'p_SMR_multi': 0.3568056, 'p_HEIDI': 0.6054701, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1743 | Q67 | What is the top-associated SNP of the gene SMCP in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | There are no SNPs within the gene SMCP in Whole Brain meta-analysis mQTL omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SMCP" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_415314', 'topRSID': 'rs11587012', 'Disease': 'PD', 'Gene': 'SMCP', 'p_SMR_multi': 0.05605472, 'p_HEIDI': 0.1316549, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_4... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.50 | Q67 | What is the top-associated SNP of the gene NSFP1 in Whole Blood eQTL GTEx omic data for PSP and is it functionally significant? | The top-associated SNP for NSFP1 in Whole Blood eQTL GTEx omic data for PSP is rs4792831, which has a multi-SNP SMR p-value of 8.73e-17 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "NSFP1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1684940', 'topRSID': 'rs4792831', 'Disease': 'PSP', 'Gene': 'NSFP1', 'p_SMR_multi': 8.727098000000001e-17, 'p_HEIDI': 6.115947e-25, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL GTEx', 'func_sig': 'association meets significance threshold but shows signs of linkag... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1089 | Q67 | What is the top-associated SNP of the gene ADCY10P1 in Whole Blood eQTL GTEx omic data for AD and is it functionally significant? | The top-associated SNP for ADCY10P1 in Whole Blood eQTL GTEx omic data for AD is rs72856293, which has a multi-SNP SMR p-value of 4.60e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ADCY10P1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1649224', 'topRSID': 'rs72856293', 'Disease': 'AD', 'Gene': 'ADCY10P1', 'p_SMR_multi': 4.601434e-07, 'p_HEIDI': 9.267346e-08, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL GTEx', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Lin... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1674 | Q67 | What is the top-associated SNP of the gene GRIN2A in Whole Blood mQTL omic data for PD and is it functionally significant? | There are no SNPs within the gene GRIN2A in Whole Blood mQTL omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "GRIN2A" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_974082', 'topRSID': 'rs75160553', 'Disease': 'PD', 'Gene': 'GRIN2A', 'p_SMR_multi': 0.1660595, 'p_HEIDI': 0.2126682, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_974078', 'topR... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1697 | Q67 | What is the top-associated SNP of the gene RP11-707O23.5 in Nucleus Accumbens Basal Ganglia omic data for PD and is it functionally significant? | The top-associated SNP for RP11-707O23.5 in Nucleus Accumbens Basal Ganglia omic data for PD is rs2942166, which has a multi-SNP SMR p-value of 1.44e-11 and a HEIDI of 0.22, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-707O23.5" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%nucleus accumbens basal ganglia%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1730061', 'topRSID': 'rs2942166', 'Disease': 'PD', 'Gene': 'RP11-707O23.5', 'p_SMR_multi': 1.439705e-11, 'p_HEIDI': 0.2207518, 'Omic_tissue': 'Nucleus Accumbens Basal', 'Omic_type': 'Nucleus Accumbens Basal Ganglia', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.686 | Q67 | What is the top-associated SNP of the gene ARL17A in Spinalcord eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for ARL17A in Spinalcord eQTL omic data for PSP is rs242557, which has a multi-SNP SMR p-value of 1.11e-10 and a HEIDI of 0.04, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARL17A" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%spinalcord eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_30485', 'topRSID': 'rs242557', 'Disease': 'PSP', 'Gene': 'ARL17A', 'p_SMR_multi': 1.114835e-10, 'p_HEIDI': 0.04407374, 'Omic_tissue': 'Spinalcord', 'Omic_type': 'Spinalcord eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1485 | Q67 | What is the top-associated SNP of the gene RP11-707O23.5 in Frontal Cortex BA9 eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for RP11-707O23.5 in Frontal Cortex BA9 eQTL omic data for PSP is rs1981997, which has a multi-SNP SMR p-value of 1.52e-15 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-707O23.5" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%frontal cortex ba9 eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1170871', 'topRSID': 'rs1981997', 'Disease': 'PSP', 'Gene': 'RP11-707O23.5', 'p_SMR_multi': 1.523364e-15, 'p_HEIDI': 1.563678e-16, 'Omic_tissue': 'Frontal Cortex', 'Omic_type': 'Frontal Cortex BA9 eQTL', 'func_sig': 'association meets significance threshold but shows signs of li... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1455 | Q67 | What is the top-associated SNP of the gene RP11-259G18.1 in Whole Blood eQTL eQTLgen omic data for PSP and is it functionally significant? | The top-associated SNP for RP11-259G18.1 in Whole Blood eQTL eQTLgen omic data for PSP is rs169201, which has a multi-SNP SMR p-value of 4.86e-40 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-259G18.1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1579425', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'RP11-259G18.1', 'p_SMR_multi': 4.864652e-40, 'p_HEIDI': 8.070724e-11, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linka... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1486 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for MAPT in Whole Brain meta-analysis mQTL omic data for PD is rs41543317, which has a multi-SNP SMR p-value of 1.27e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_491114', 'topRSID': 'rs17652121', 'Disease': 'PD', 'Gene': 'MAPT', 'p_SMR_multi': 4.729064e-14, 'p_HEIDI': 0.04416005, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_49... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1292 | Q67 | What is the top-associated SNP of the gene ARHGAP27 in Whole Blood mQTL omic data for PSP and is it functionally significant? | The top-associated SNP for ARHGAP27 in Whole Blood mQTL omic data for PSP is rs11012, which has a multi-SNP SMR p-value of 1.36e-13 and a HEIDI of 0.08, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARHGAP27" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1041709', 'topRSID': 'rs11012', 'Disease': 'PSP', 'Gene': 'ARHGAP27', 'p_SMR_multi': 3.175631e-40, 'p_HEIDI': 2.761191e-07, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Di... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1232 | Q67 | What is the top-associated SNP of the gene HDAC4 in Whole Blood mQTL omic data for PD and is it functionally significant? | There are no SNPs within the gene HDAC4 in Whole Blood mQTL omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "HDAC4" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1021336', 'topRSID': 'rs34624648', 'Disease': 'PD', 'Gene': 'HDAC4', 'p_SMR_multi': 0.01594804, 'p_HEIDI': 0.4331417, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_1021253', 'to... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.525 | Q67 | What is the top-associated SNP of the gene PLAC9 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for PLAC9 in Whole Blood mQTL omic data for AD is rs2784768, which has a multi-SNP SMR p-value of 1.14e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PLAC9" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_572609', 'topRSID': 'rs745182', 'Disease': 'AD', 'Gene': 'PLAC9', 'p_SMR_multi': 1.896037e-07, 'p_HEIDI': 0.0007834608, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1654 | Q67 | What is the top-associated SNP of the gene RP11-798G7.5 in Whole Blood eQTL eQTLgen omic data for PSP and is it functionally significant? | The top-associated SNP for RP11-798G7.5 in Whole Blood eQTL eQTLgen omic data for PSP is rs11012, which has a multi-SNP SMR p-value of 1.48e-20 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-798G7.5" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1579414', 'topRSID': 'rs11012', 'Disease': 'PSP', 'Gene': 'RP11-798G7.5', 'p_SMR_multi': 1.4757229999999998e-20, 'p_HEIDI': 5.109127e-13, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.908 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for MAPT in Whole Blood mQTL omic data for PD is rs112995313, which has a multi-SNP SMR p-value of 1.14e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_948891', 'topRSID': 'rs62063271', 'Disease': 'PD', 'Gene': 'MAPT', 'p_SMR_multi': 6.382411e-15, 'p_HEIDI': 2.368028e-06, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1904 | Q67 | What is the top-associated SNP of the gene IDUA in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for IDUA in Whole Brain meta-analysis mQTL omic data for PD is rs11248061, which has a multi-SNP SMR p-value of 1.67e-07 and a HEIDI of 0.09, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "IDUA" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_429873', 'topRSID': 'rs1051613', 'Disease': 'PD', 'Gene': 'IDUA', 'p_SMR_multi': 4.554749e-13, 'p_HEIDI': 2.213052e-05, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1242 | Q67 | What is the top-associated SNP of the gene MVP in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for MVP in Whole Blood eQTL eQTLgen omic data for AD is rs10204, which has a multi-SNP SMR p-value of 2.93e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MVP" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1501435', 'topRSID': 'rs10204', 'Disease': 'AD', 'Gene': 'MVP', 'p_SMR_multi': 2.926878e-06, 'p_HEIDI': 0.000301623, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage D... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.24 | Q67 | What is the top-associated SNP of the gene RP11-385F7.1 in Cerebellar Hemisphere eQTL omic data for AD and is it functionally significant? | The top-associated SNP for RP11-385F7.1 in Cerebellar Hemisphere eQTL omic data for AD is rs9369717, which has a multi-SNP SMR p-value of 5.20e-07 and a HEIDI of 0.04, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-385F7.1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%cerebellar hemisphere eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1172618', 'topRSID': 'rs9369717', 'Disease': 'AD', 'Gene': 'RP11-385F7.1', 'p_SMR_multi': 5.195907e-07, 'p_HEIDI': 0.03864161, 'Omic_tissue': 'Cerebellar Hemisphere', 'Omic_type': 'Cerebellar Hemisphere eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.779 | Q67 | What is the top-associated SNP of the gene BIN1 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for BIN1 in Whole Brain meta-analysis mQTL omic data for AD is rs730471, which has a multi-SNP SMR p-value of 2.12e-16 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "BIN1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_46339', 'topRSID': 'rs730471', 'Disease': 'AD', 'Gene': 'BIN1', 'p_SMR_multi': 2.124617e-16, 'p_HEIDI': 3.050073e-22, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Li... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.65 | Q67 | What is the top-associated SNP of the gene CRHR1 in Whole Brain meta-analysis mQTL omic data for PSP and is it functionally significant? | The top-associated SNP for CRHR1 in Whole Brain meta-analysis mQTL omic data for PSP is rs12373139, which has a multi-SNP SMR p-value of 5.15e-18 and a HEIDI of 0.22, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CRHR1" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_560849', 'topRSID': 'rs12373139', 'Disease': 'PSP', 'Gene': 'CRHR1', 'p_SMR_multi': 5.146795e-18, 'p_HEIDI': 0.2191273, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_5... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1366 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for MAPT in Whole Brain meta-analysis mQTL omic data for AD is rs17650872, which has a multi-SNP SMR p-value of 4.32e-07 and a HEIDI of 0.64, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_115183', 'topRSID': 'rs17650872', 'Disease': 'AD', 'Gene': 'MAPT', 'p_SMR_multi': 4.321768e-07, 'p_HEIDI': 0.6403735, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_115... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.191 | Q67 | What is the top-associated SNP of the gene MGC57346 in Whole Blood mQTL omic data for PSP and is it functionally significant? | The top-associated SNP for MGC57346 in Whole Blood mQTL omic data for PSP is rs169201, which has a multi-SNP SMR p-value of 5.68e-21 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MGC57346" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1041718', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'MGC57346', 'p_SMR_multi': 5.68239e-21, 'p_HEIDI': 4.486385e-06, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Di... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1630 | Q67 | What is the top-associated SNP of the gene SLC26A1 in Cortex eQTL GTEx omic data for PD and is it functionally significant? | The top-associated SNP for SLC26A1 in Cortex eQTL GTEx omic data for PD is rs11936407, which has a multi-SNP SMR p-value of 5.28e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SLC26A1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cortex eqtl gtex%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1259978', 'topRSID': 'rs11936407', 'Disease': 'PD', 'Gene': 'SLC26A1', 'p_SMR_multi': 5.277958e-07, 'p_HEIDI': 3.18335e-06, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL GTEx', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequi... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1395 | Q67 | What is the top-associated SNP of the gene LRRC37A2 in Amygdala eQTL omic data for AD and is it functionally significant? | The top-associated SNP for LRRC37A2 in Amygdala eQTL omic data for AD is rs2942166, which has a multi-SNP SMR p-value of 2.54e-06 and a HEIDI of 0.39, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "LRRC37A2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%amygdala eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1598275', 'topRSID': 'rs2942166', 'Disease': 'AD', 'Gene': 'LRRC37A2', 'p_SMR_multi': 2.54217e-06, 'p_HEIDI': 0.3929416, 'Omic_tissue': 'Amygdala', 'Omic_type': 'Amygdala eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1547 | Q67 | What is the top-associated SNP of the gene CAMTA1 in Whole Brain meta-analysis mQTL omic data for FTD and is it functionally significant? | There are no SNPs within the gene CAMTA1 in Whole Brain meta-analysis mQTL omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CAMTA1" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_226375', 'topRSID': 'rs1750824', 'Disease': 'FTD', 'Gene': 'CAMTA1', 'p_SMR_multi': 0.06099203, 'p_HEIDI': 0.04422341, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_tex... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.346 | Q67 | What is the top-associated SNP of the gene MRPL55 in Cerebellum eQTL omic data for AD and is it functionally significant? | There are no SNPs within the gene MRPL55 in Cerebellum eQTL omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MRPL55" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%cerebellum eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_2468', 'topRSID': 'rs1832734', 'Disease': 'AD', 'Gene': 'MRPL55', 'p_SMR_multi': 0.2429041, 'p_HEIDI': 0.6256503, 'Omic_tissue': 'Cerebellum', 'Omic_type': 'Cerebellum eQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_1686369', 'topRSID'... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.400 | Q67 | What is the top-associated SNP of the gene AC073842.19 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for AC073842.19 in Whole Brain meta-analysis mQTL omic data for AD is rs11505847, which has a multi-SNP SMR p-value of 6.02e-11 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "AC073842.19" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_74038', 'topRSID': 'rs11505847', 'Disease': 'AD', 'Gene': 'AC073842.19', 'p_SMR_multi': 6.018154e-11, 'p_HEIDI': 0.006186833, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of lin... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1393 | Q67 | What is the top-associated SNP of the gene ZSCAN21 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD and is it functionally significant? | The top-associated SNP for ZSCAN21 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD is rs4729571, which has a multi-SNP SMR p-value of 3.26e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ZSCAN21" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT 10... | [{'UUID': 'NDD_SMR_genes_all_update_text_1392615', 'topRSID': 'rs4729571', 'Disease': 'AD', 'Gene': 'ZSCAN21', 'p_SMR_multi': 3.258773e-09, 'p_HEIDI': 0.0003045729, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'association meets significance thre... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1876 | Q67 | What is the top-associated SNP of the gene RP11-707O23.5 in Whole Brain eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for RP11-707O23.5 in Whole Brain eQTL omic data for PSP is rs11012, which has a multi-SNP SMR p-value of 9.17e-13 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-707O23.5" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole brain eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1646040', 'topRSID': 'rs11012', 'Disease': 'PSP', 'Gene': 'RP11-707O23.5', 'p_SMR_multi': 9.170021e-13, 'p_HEIDI': 0.0001098604, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linka... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.199 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for MAPT in Whole Brain meta-analysis mQTL omic data for PD is rs9944484, which has a multi-SNP SMR p-value of 8.71e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_491114', 'topRSID': 'rs17652121', 'Disease': 'PD', 'Gene': 'MAPT', 'p_SMR_multi': 4.729064e-14, 'p_HEIDI': 0.04416005, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_49... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1173 | Q67 | What is the top-associated SNP of the gene RP11-798G7.8 in Tibial Nerve eQTL omic data for PD and is it functionally significant? | The top-associated SNP for RP11-798G7.8 in Tibial Nerve eQTL omic data for PD is rs6503453, which has a multi-SNP SMR p-value of 1.36e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-798G7.8" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%tibial nerve eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1328925', 'topRSID': 'rs6503453', 'Disease': 'PD', 'Gene': 'RP11-798G7.8', 'p_SMR_multi': 1.361595e-08, 'p_HEIDI': 1.087544e-08, 'Omic_tissue': 'Tibial Nerve', 'Omic_type': 'Tibial Nerve eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Lin... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.320 | Q67 | What is the top-associated SNP of the gene ARL17B in Liver eQTL omic data for PSP and is it functionally significant? | The top-associated SNP for ARL17B in Liver eQTL omic data for PSP is rs4792831, which has a multi-SNP SMR p-value of 2.43e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARL17B" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%liver eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1478190', 'topRSID': 'rs4792831', 'Disease': 'PSP', 'Gene': 'ARL17B', 'p_SMR_multi': 2.430902e-07, 'p_HEIDI': -9999.0, 'Omic_tissue': 'Liver', 'Omic_type': 'Liver eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1002 | Q67 | What is the top-associated SNP of the gene ABCA7 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for ABCA7 in Whole Blood mQTL omic data for AD is rs34606911, which has a multi-SNP SMR p-value of 2.59e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ABCA7" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_634279', 'topRSID': 'rs3764642', 'Disease': 'AD', 'Gene': 'ABCA7', 'p_SMR_multi': 2.490416e-10, 'p_HEIDI': 0.0002263415, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.223 | Q67 | What is the top-associated SNP of the gene APOC1P1 in Liver eQTL omic data for AD and is it functionally significant? | The top-associated SNP for APOC1P1 in Liver eQTL omic data for AD is rs5112, which has a multi-SNP SMR p-value of 2.43e-13 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "APOC1P1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%liver eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1466878', 'topRSID': 'rs5112', 'Disease': 'AD', 'Gene': 'APOC1P1', 'p_SMR_multi': 2.42788e-13, 'p_HEIDI': 1.039469e-06, 'Omic_tissue': 'Liver', 'Omic_type': 'Liver eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1220 | Q67 | What is the top-associated SNP of the gene INO80E in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for INO80E in Whole Brain meta-analysis mQTL omic data for AD is rs10871451, which has a multi-SNP SMR p-value of 2.53e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "INO80E" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_109450', 'topRSID': 'rs10871451', 'Disease': 'AD', 'Gene': 'INO80E', 'p_SMR_multi': 2.528427e-08, 'p_HEIDI': 0.003081132, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.103 | Q67 | What is the top-associated SNP of the gene TRIM10 in Whole Blood mQTL omic data for PSP and is it functionally significant? | There are no SNPs within the gene TRIM10 in Whole Blood mQTL omic data that are significantly associated with PSP, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TRIM10" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1100000', 'topRSID': 'rs2074478', 'Disease': 'PSP', 'Gene': 'TRIM10', 'p_SMR_multi': 0.07429907, 'p_HEIDI': 0.9769588, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_1100003', 't... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1655 | Q67 | What is the top-associated SNP of the gene ZNF232 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD and is it functionally significant? | The top-associated SNP for ZNF232 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for AD is rs143649705, which has a multi-SNP SMR p-value of 6.35e-07 and a HEIDI of 0.02, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ZNF232" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1396456', 'topRSID': 'rs143649705', 'Disease': 'AD', 'Gene': 'ZNF232', 'p_SMR_multi': 6.34974e-07, 'p_HEIDI': 0.01686104, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.949 | Q67 | What is the top-associated SNP of the gene ZNF232 in Skeletal Muscle eQTL omic data for AD and is it functionally significant? | The top-associated SNP for ZNF232 in Skeletal Muscle eQTL omic data for AD is rs143649705, which has a multi-SNP SMR p-value of 1.44e-06 and a HEIDI of 0.22, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ZNF232" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%skeletal muscle eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1342981', 'topRSID': 'rs143649705', 'Disease': 'AD', 'Gene': 'ZNF232', 'p_SMR_multi': 1.438383e-06, 'p_HEIDI': 0.2214291, 'Omic_tissue': 'Skeletal Muscle', 'Omic_type': 'Skeletal Muscle eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1939 | Q67 | What is the top-associated SNP of the gene TSC22D4 in Cortex eQTL metaBrain omic data for PD and is it functionally significant? | There are no SNPs within the gene TSC22D4 in Cortex eQTL metaBrain omic data that are significantly associated with PD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TSC22D4" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cortex eqtl metabrain%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1146600', 'topRSID': 'rs11769700', 'Disease': 'PD', 'Gene': 'TSC22D4', 'p_SMR_multi': 0.3023651, 'p_HEIDI': 0.4730595, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL metaBrain', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1914 | Q67 | What is the top-associated SNP of the gene TMEM175 in Whole Blood mQTL omic data for PD and is it functionally significant? | The top-associated SNP for TMEM175 in Whole Blood mQTL omic data for PD is rs935977, which has a multi-SNP SMR p-value of 5.34e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TMEM175" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_996283', 'topRSID': 'rs6813110', 'Disease': 'PD', 'Gene': 'TMEM175', 'p_SMR_multi': 2.618289e-11, 'p_HEIDI': 0.0001221027, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dis... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1127 | Q67 | What is the top-associated SNP of the gene HSD3B7 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for PD and is it functionally significant? | The top-associated SNP for HSD3B7 in Multi Ancestry Whole Brain Meta-analysis eQTL omic data for PD is rs897986, which has a multi-SNP SMR p-value of 5.76e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "HSD3B7" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%multi ancestry whole brain meta-analysis eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1435342', 'topRSID': 'rs897986', 'Disease': 'PD', 'Gene': 'HSD3B7', 'p_SMR_multi': 5.760116e-08, 'p_HEIDI': 5.797939e-09, 'Omic_tissue': 'Multi Ancestry Whole Brain', 'Omic_type': 'Multi Ancestry Whole Brain Meta-analysis eQTL', 'func_sig': 'association meets significance thresh... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1052 | Q67 | What is the top-associated SNP of the gene SPPL2C in Cortex eQTL metaBrain omic data for PSP and is it functionally significant? | The top-associated SNP for SPPL2C in Cortex eQTL metaBrain omic data for PSP is rs393152, which has a multi-SNP SMR p-value of 2.37e-14 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "SPPL2C" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%cortex eqtl metabrain%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1154395', 'topRSID': 'rs393152', 'Disease': 'PSP', 'Gene': 'SPPL2C', 'p_SMR_multi': 2.367158e-14, 'p_HEIDI': 6.22534e-10, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL metaBrain', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dise... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1538 | Q67 | What is the top-associated SNP of the gene BTNL2 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for BTNL2 in Whole Blood mQTL omic data for AD is rs28366339, which has a multi-SNP SMR p-value of 1.08e-06 and a HEIDI of 0.31, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "BTNL2" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_621688', 'topRSID': 'rs116522341', 'Disease': 'AD', 'Gene': 'BTNL2', 'p_SMR_multi': 2.681311e-09, 'p_HEIDI': 2.28461e-05, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dise... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.356 | Q67 | What is the top-associated SNP of the gene NDUFAF6 in Whole Brain meta-analysis mQTL omic data for AD and is it functionally significant? | The top-associated SNP for NDUFAF6 in Whole Brain meta-analysis mQTL omic data for AD is rs896853, which has a multi-SNP SMR p-value of 3.93e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "NDUFAF6" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_79381', 'topRSID': 'rs10097617', 'Disease': 'AD', 'Gene': 'NDUFAF6', 'p_SMR_multi': 2.455946e-08, 'p_HEIDI': 0.001210675, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.603 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Brain meta-analysis mQTL omic data for PD and is it functionally significant? | The top-associated SNP for MAPT in Whole Brain meta-analysis mQTL omic data for PD is rs17651507, which has a multi-SNP SMR p-value of 1.83e-07 and a HEIDI of 0.02, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_491114', 'topRSID': 'rs17652121', 'Disease': 'PD', 'Gene': 'MAPT', 'p_SMR_multi': 4.729064e-14, 'p_HEIDI': 0.04416005, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_49... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1559 | Q67 | What is the top-associated SNP of the gene DGKQ in Whole Blood eQTL eQTLgen omic data for PD and is it functionally significant? | The top-associated SNP for DGKQ in Whole Blood eQTL eQTLgen omic data for PD is rs1377586, which has a multi-SNP SMR p-value of 4.12e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "DGKQ" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1555640', 'topRSID': 'rs1377586', 'Disease': 'PD', 'Gene': 'DGKQ', 'p_SMR_multi': 4.119889e-09, 'p_HEIDI': 0.0007952652, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linka... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1350 | Q67 | What is the top-associated SNP of the gene TRIM10 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for TRIM10 in Whole Blood mQTL omic data for AD is rs112863641, which has a multi-SNP SMR p-value of 2.61e-06 and a HEIDI of 0.13, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TRIM10" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_620312', 'topRSID': 'rs112863641', 'Disease': 'AD', 'Gene': 'TRIM10', 'p_SMR_multi': 1.381851e-06, 'p_HEIDI': 0.2819747, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_620309', 'topR... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1359 | Q67 | What is the top-associated SNP of the gene KLHL7-AS1 in Whole Blood eQTL eQTLgen omic data for PD and is it functionally significant? | The top-associated SNP for KLHL7-AS1 in Whole Blood eQTL eQTLgen omic data for PD is rs6461691, which has a multi-SNP SMR p-value of 3.31e-08 and a HEIDI of 0.02, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KLHL7-AS1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1557759', 'topRSID': 'rs6461691', 'Disease': 'PD', 'Gene': 'KLHL7-AS1', 'p_SMR_multi': 3.305227e-08, 'p_HEIDI': 0.01620941, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.947 | Q67 | What is the top-associated SNP of the gene MAPT in Whole Blood mQTL omic data for PSP and is it functionally significant? | The top-associated SNP for MAPT in Whole Blood mQTL omic data for PSP is rs169201, which has a multi-SNP SMR p-value of 9.09e-08 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT" AND Disease = "PSP" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1041740', 'topRSID': 'rs169201', 'Disease': 'PSP', 'Gene': 'MAPT', 'p_SMR_multi': 3.1929999999999995e-44, 'p_HEIDI': 3.11336e-12, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Link... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.348 | Q67 | What is the top-associated SNP of the gene CCDC189 in Cortex eQTL metaBrain omic data for PD and is it functionally significant? | The top-associated SNP for CCDC189 in Cortex eQTL metaBrain omic data for PD is rs8048448, which has a multi-SNP SMR p-value of 3.32e-08 and a HEIDI of 0.01, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CCDC189" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%cortex eqtl metabrain%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1140846', 'topRSID': 'rs8048448', 'Disease': 'PD', 'Gene': 'CCDC189', 'p_SMR_multi': 3.320725e-08, 'p_HEIDI': 0.01141197, 'Omic_tissue': 'Cortex', 'Omic_type': 'Cortex eQTL metaBrain', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.606 | Q67 | What is the top-associated SNP of the gene ARL17A in Tibial Nerve eQTL omic data for PD and is it functionally significant? | The top-associated SNP for ARL17A in Tibial Nerve eQTL omic data for PD is rs62074125, which has a multi-SNP SMR p-value of 8.73e-09 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARL17A" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%tibial nerve eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1328942', 'topRSID': 'rs62074125', 'Disease': 'PD', 'Gene': 'ARL17A', 'p_SMR_multi': 8.729084e-09, 'p_HEIDI': 3.334365e-13, 'Omic_tissue': 'Tibial Nerve', 'Omic_type': 'Tibial Nerve eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage ... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.719 | Q67 | What is the top-associated SNP of the gene RP11-18I14.10 in Substantia nigra eQTL omic data for LBD and is it functionally significant? | There are no SNPs within the gene RP11-18I14.10 in Substantia nigra eQTL omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "RP11-18I14.10" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%substantia nigra eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1450064', 'topRSID': 'rs150098322', 'Disease': 'LBD', 'Gene': 'RP11-18I14.10', 'p_SMR_multi': 0.1022781, 'p_HEIDI': 0.3607242, 'Omic_tissue': 'Substantia nigra', 'Omic_type': 'Substantia nigra eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.118 | Q67 | What is the top-associated SNP of the gene ARHGEF5 in Whole Blood mQTL omic data for LBD and is it functionally significant? | There are no SNPs within the gene ARHGEF5 in Whole Blood mQTL omic data that are significantly associated with LBD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ARHGEF5" AND Disease = "LBD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_859744', 'topRSID': 'rs700259', 'Disease': 'LBD', 'Gene': 'ARHGEF5', 'p_SMR_multi': 0.9415026, 'p_HEIDI': 0.8776761, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_859743', 'topR... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.617 | Q67 | What is the top-associated SNP of the gene FAM63B in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for FAM63B in Whole Blood mQTL omic data for AD is rs395601, which has a multi-SNP SMR p-value of 2.93e-06 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "FAM63B" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_646472', 'topRSID': 'rs2555357', 'Disease': 'AD', 'Gene': 'FAM63B', 'p_SMR_multi': 5.360861e-07, 'p_HEIDI': 0.0001142865, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Dise... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1013 | Q67 | What is the top-associated SNP of the gene MAPT-AS1 in Prefrontal Cortex eQTL omic data for AD and is it functionally significant? | The top-associated SNP for MAPT-AS1 in Prefrontal Cortex eQTL omic data for AD is rs1819040, which has a multi-SNP SMR p-value of 1.74e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "MAPT-AS1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%prefrontal cortex eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1203009', 'topRSID': 'rs1819040', 'Disease': 'AD', 'Gene': 'MAPT-AS1', 'p_SMR_multi': 1.741788e-07, 'p_HEIDI': 0.008558721, 'Omic_tissue': 'Prefrontal Cortex', 'Omic_type': 'Prefrontal Cortex eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1265 | Q67 | What is the top-associated SNP of the gene NFYA in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for NFYA in Whole Blood mQTL omic data for AD is rs72856298, which has a multi-SNP SMR p-value of 5.63e-10 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "NFYA" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_622639', 'topRSID': 'rs72856298', 'Disease': 'AD', 'Gene': 'NFYA', 'p_SMR_multi': 3.336665e-10, 'p_HEIDI': 1.123977e-10, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Diseq... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1489 | Q67 | What is the top-associated SNP of the gene ZSWIM7 in Whole Brain eQTL omic data for PD and is it functionally significant? | The top-associated SNP for ZSWIM7 in Whole Brain eQTL omic data for PD is rs1860643, which has a multi-SNP SMR p-value of 6.55e-07 and a HEIDI of 0.24, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "ZSWIM7" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole brain eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1640053', 'topRSID': 'rs1860643', 'Disease': 'PD', 'Gene': 'ZSWIM7', 'p_SMR_multi': 6.546399e-07, 'p_HEIDI': 0.2378725, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain eQTL', 'func_sig': 'functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.489 | Q67 | What is the top-associated SNP of the gene KANSL1 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for KANSL1 in Whole Blood mQTL omic data for AD is rs2532233, which has a multi-SNP SMR p-value of 1.65e-06 and a HEIDI of 0.1, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_591218', 'topRSID': 'rs2532233', 'Disease': 'AD', 'Gene': 'KANSL1', 'p_SMR_multi': 1.651529e-06, 'p_HEIDI': 0.0968839, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_591214', 'topRSI... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1711 | Q67 | What is the top-associated SNP of the gene NSF in Whole Blood eQTL eQTLgen omic data for AD and is it functionally significant? | The top-associated SNP for NSF in Whole Blood eQTL eQTLgen omic data for AD is rs62074125, which has a multi-SNP SMR p-value of 4.92e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "NSF" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1502459', 'topRSID': 'rs62074125', 'Disease': 'AD', 'Gene': 'NSF', 'p_SMR_multi': 4.92066e-07, 'p_HEIDI': 0.003636118, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.787 | Q67 | What is the top-associated SNP of the gene CNOT6L in Skeletal Muscle eQTL omic data for AD and is it functionally significant? | There are no SNPs within the gene CNOT6L in Skeletal Muscle eQTL omic data that are significantly associated with AD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "CNOT6L" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%skeletal muscle eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1339227', 'topRSID': 'rs6839504', 'Disease': 'AD', 'Gene': 'CNOT6L', 'p_SMR_multi': 0.09364523, 'p_HEIDI': 0.1176753, 'Omic_tissue': 'Skeletal Muscle', 'Omic_type': 'Skeletal Muscle eQTL', 'func_sig': 'not functionally significant'}] | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.881 | Q67 | What is the top-associated SNP of the gene TSPAN14 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for TSPAN14 in Whole Blood mQTL omic data for AD is rs10788639, which has a multi-SNP SMR p-value of 2.33e-06 and a HEIDI of 0.14, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "TSPAN14" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_572646', 'topRSID': 'rs7088877', 'Disease': 'AD', 'Gene': 'TSPAN14', 'p_SMR_multi': 5.205964e-09, 'p_HEIDI': 0.01998933, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_572650', 'topR... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.1555 | Q67 | What is the top-associated SNP of the gene STX1B in Tibial Nerve eQTL omic data for PD and is it functionally significant? | The top-associated SNP for STX1B in Tibial Nerve eQTL omic data for PD is rs58726213, which has a multi-SNP SMR p-value of 2.38e-07 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "STX1B" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%tibial nerve eqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1328405', 'topRSID': 'rs58726213', 'Disease': 'PD', 'Gene': 'STX1B', 'p_SMR_multi': 2.384535e-07, 'p_HEIDI': 0.002059639, 'Omic_tissue': 'Tibial Nerve', 'Omic_type': 'Tibial Nerve eQTL', 'func_sig': 'association meets significance threshold but shows signs of linkage/ Linkage Di... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.567 | Q67 | What is the top-associated SNP of the gene PTPN7 in Whole Brain meta-analysis mQTL omic data for FTD and is it functionally significant? | There are no SNPs within the gene PTPN7 in Whole Brain meta-analysis mQTL omic data that are significantly associated with FTD, indicating that it is not functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "PTPN7" AND Disease = "FTD" AND LOWER(Omic_type) LIKE "%whole brain meta-analysis mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_232259', 'topRSID': 'rs3934668', 'Disease': 'FTD', 'Gene': 'PTPN7', 'p_SMR_multi': 0.1146373, 'p_HEIDI': 0.2399868, 'Omic_tissue': 'Whole Brain', 'Omic_type': 'Whole Brain meta-analysis mQTL', 'func_sig': 'not functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_2... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.254 | Q67 | What is the top-associated SNP of the gene EPHA1-AS1 in Whole Blood mQTL omic data for AD and is it functionally significant? | The top-associated SNP for EPHA1-AS1 in Whole Blood mQTL omic data for AD is rs75045569, which has a multi-SNP SMR p-value of 6.94e-09 and a HEIDI of 0.16, indicating that it is functionally significant. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "EPHA1-AS1" AND Disease = "AD" AND LOWER(Omic_type) LIKE "%whole blood mqtl%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_587067', 'topRSID': 'rs75045569', 'Disease': 'AD', 'Gene': 'EPHA1-AS1', 'p_SMR_multi': 6.942181e-09, 'p_HEIDI': 0.1635299, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood mQTL', 'func_sig': 'functionally significant'}, {'UUID': 'NDD_SMR_genes_all_update_text_587068', 'to... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
Q67.242 | Q67 | What is the top-associated SNP of the gene KANSL1-AS1 in Whole Blood eQTL eQTLgen omic data for PD and is it functionally significant? | The top-associated SNP for KANSL1-AS1 in Whole Blood eQTL eQTLgen omic data for PD is rs2532233, which has a multi-SNP SMR p-value of 6.35e-15 but is not functionally significant as the association meets significance threshold but shows signs of linkage/ Linkage Disequilibrium. | SELECT UUID, topRSID, Disease, Gene, p_SMR_multi, p_HEIDI, Omic_tissue, Omic_type, func_sig
FROM `{project_id}.{dataset_name}.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Gene = "KANSL1-AS1" AND Disease = "PD" AND LOWER(Omic_type) LIKE "%whole blood eqtl eqtlgen%"
ORDER BY p_SMR_multi
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1564785', 'topRSID': 'rs2532233', 'Disease': 'PD', 'Gene': 'KANSL1-AS1', 'p_SMR_multi': 6.350781e-15, 'p_HEIDI': 5.354246e-07, 'Omic_tissue': 'Whole Blood', 'Omic_type': 'Whole Blood eQTL eQTLgen', 'func_sig': 'association meets significance threshold but shows signs of linkage/... | general | Select, Similarity Search, Multi-Filter, Order By | Functional Significance |
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