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depleted\tstatus,\tand\tmuscle\twasting.\tHowever,\tprotein\tkinetic\tstudies\tdemonstrate\tincreased\tnitrogen\tlosses\tonly\tin\npatients\twith\tfulminant\thepatic\tfailure\tor\tdecompensated\tdisease,\tbut\tnot\tin\tstable\tcirrhosis.\nPatients\twith\tcirrhosis\talso\thave\tincreased\tprotein\tutilization.\tStudies\...
[ -0.002950924215838313, -0.05165265500545502, 0.04201512411236763, -0.0014025004347786307, -0.09278642386198044, -0.015006601810455322, 0.057130116969347, 0.08336804807186127, -0.01740015670657158, 0.05807976797223091, 0.09220924973487854, -0.03900670260190964, 0.014241337776184082, 0.04039...
mean\tprotein\trequirement\tto\tachieve\tnitrogen\tbalance\tin\tstable\tcirrhosis.\n\tTherefore\tin\tuncomplicated\thepatitis\tor\ncirrhosis\twith\tor\twithout\tencephalopathy,\tprotein\trequirements\trange\tfrom\t1\tto\t1.5\tg/kg\tof\tideal\tweight\tper\tday\n(\nAmodio\tet\tal,\t2013\n).
[ 0.02224370278418064, -0.09123121201992035, 0.009666437283158302, -0.0031061212066560984, -0.11798720061779022, -0.006530632730573416, 0.05095244199037552, 0.12041912972927094, -0.02979889139533043, 0.04949231445789337, 0.10791826248168945, -0.029316190630197525, 0.03395845368504524, 0.0854...
(\nAmodio\tet\tal,\t2013\n).\nTo\tpromote\tnitrogen\taccumulation\tor\tpositive\tbalance,\tat\tleast\t1.2\tto\t1.3\tg/kg\tdaily\tis\tneeded.\tIn\tsituations\tof\nstress\tsuch\tas\talcoholic\thepatitis\tor\tdecompensated\tdisease\t(sepsis,\tinfection,\tgastrointestinal\tbleeding,\tor\n\tsevere
[ -0.006539805326610804, -0.08862648159265518, -0.014060267247259617, -0.025117240846157074, -0.0755038857460022, 0.005707951262593269, 0.0360199436545372, 0.05020083859562874, -0.07124978303909302, 0.07536535710096359, 0.11266344040632248, -0.030498536303639412, -0.010371401906013489, 0.075...
severe\nascites),\tat\tleast\t1.5\tg\tof\tprotein\tper\tkg\tper\tday\tshould\tbe\tprovided.\tSmall\tfrequent\tmeals\tnot\tonly\tprovide\tadditional\ncalories\tbut\talso\tprevent\tgluconeogenesis\tand\twasting\tof\tmuscle\t(\nAmodio\tet\tal,\t2014\n).\nVitamins\tand\tminerals
[ -0.029917612671852112, -0.06059760972857475, 0.04971253499388695, -0.013017596676945686, -0.047620419412851334, 0.0022382549941539764, 0.07181888073682785, 0.13656114041805267, -0.038487035781145096, 0.024987850338220596, 0.1014045923948288, 0.012460601516067982, 0.04250822216272354, 0.050...
Amodio\tet\tal,\t2014\n).\nVitamins\tand\tminerals\nVitamin\tand\tmineral\tsupplementation\tshould\tbe\tconsidered\tfor\tall\tpatients\twith\tESLD\tbecause\tof\tthe\tessential\trole\tof\nthe\tliver\tin\tnutrient\ttransport,\tstorage,\n\tand\tmetabolism,\tin\taddition\tto\tthe\tpresence\tof\tnutrient\tdepletions\tdue\tt...
[ -0.020306292921304703, -0.07409518212080002, 0.027021586894989014, -0.007660496514290571, -0.040013689547777176, 0.017142292112112045, 0.12224231660366058, 0.10223191976547241, -0.013613884337246418, 0.004912605043500662, 0.09104712307453156, 0.014183749444782734, 0.064765565097332, 0.0649...
drugs\t(\nTable\t28.4\n).\tVitamin\tdeficiencies\tcan\tcontribute\tto\tcomplications.\tFor\texample,\tfolate\tand\tvitamin\tB\n12\ndeficiencies\tcan\tlead\tto\tmacrocytic\tanemia.\tDeficiency\tof\tpyridoxine,\tthiamin,\tor\tvitamin\tB\n12\n\tcan\tresult\tin\nneuropathy.\tConfusion,\tataxia,\tand\tocular\tdisturbances\t...
[ -0.004015862010419369, -0.06863463670015335, -0.006870890501886606, 0.012122592888772488, -0.06118793040513992, -0.014790129847824574, 0.03589055314660072, 0.09005536139011383, -0.08719509094953537, 0.01463073119521141, 0.04029771313071251, 0.014741701073944569, 0.017222506925463676, 0.067...
TABLE\t28.4\nVitamin\tand\tMineral\tDeficits\tin\tSevere\tHepatic\tFailure\nVitamin\tor\nMineral\nPredisposing\tFactors\nSigns\tof\tDeficiency\t(See\n\t\nAppendix\t21\n)\nVitamin\tA\nSteatorrhea,\tneomycin,\ncholestyramine,\nalcoholism\nNight\tblindness,\tincreased\tinfection\trisk\nVitamin\tB\n1\n(thiamine)\nAlcoholis...
[ 0.001124627306126058, -0.13056619465351105, -0.0021722714882344007, -0.002297559753060341, -0.05950202792882919, 0.00258048577234149, 0.04198167100548744, 0.08316890895366669, -0.049305062741041183, 0.026147840544581413, 0.050361670553684235, -0.02988547272980213, 0.04516518488526344, 0.03...
Vitamin\tB\n1\n(thiamine)\nAlcoholism,\thigh-\ncarbohydrate\tdiet\nNeuropathy,\tascites,\tedema,\tcentral\tnervous\tsystem\t(CNS)\tdysfunction\nVitamin\tB\n3\n\t(niacin)\nAlcoholism\nDermatitis,\tdementia,\tdiarrhea,\tinflammation\tof\tmucous\tmembranes\nVitamin\tB\n6\n(pyridoxine)\nAlcoholism\nMucous\tmembrane\tlesion...
[ -0.021120710298419, -0.14443764090538025, 0.015685318037867546, 0.02115260809659958, -0.04946809634566307, 0.017945442348718643, 0.02671012096107006, 0.08713739365339279, -0.07656466215848923, 0.059046290814876556, -0.0028998027555644512, -0.027100177481770515, 0.05034904181957245, 0.06131...
Mucous\tmembrane\tlesions,\tseborrheic\tdermatitis,\tglossitis,\tangular\nstomatitis,\tblepharitis,\tperipheral\tneuropathy,\tmicrocytic\tanemia,\ndepression\nVitamin\tB\n12\n(cyanocobalamin)\nAlcoholism,\ncholestyramine\nMegaloblastic\tanemia,\tglossitis,\tCNS\tdysfunction\nFolate\nAlcoholism\nMegaloblastic\tanemia,\t...
[ 0.004648312460631132, -0.08162663131952286, 0.01472257450222969, 0.010128792375326157, -0.08342643082141876, 0.020962202921509743, 0.0017174782697111368, 0.12186264991760254, -0.058960795402526855, 0.04591221362352371, -0.010377570055425167, -0.03845475614070892, 0.06208617612719536, 0.063...
Megaloblastic\tanemia,\tglossitis,\n\tirritability\nVitamin\tD\nSteatorrhea,\nglucocorticoids,\ncholestyramine\nOsteomalacia,\trickets\t(in\tchildren),\tpossible\tlink\tto\tcancer\tor\tautoimmune\ndisorders\nVitamin\tE\nSteatorrhea,\ncholestyramine\nPeripheral\tneuropathy,\tataxia,\tskeletal\tmyopathy,\tretinopathy,\ti...
[ 0.01720265857875347, -0.11000632494688034, 0.015741102397441864, -0.016763556748628616, -0.08884841203689575, -0.0008974533993750811, 0.024411724880337715, 0.11724405735731125, -0.08612869679927826, 0.05577395111322403, 0.05094742402434349, 0.006131203379482031, 0.021039200946688652, 0.058...
system\timpairment\nVitamin\tK\nSteatorrhea,\tantibiotics,\ncholestyramine\nExcessive\tbleeding,\tbruising\nIron\nChronic\tbleeding\nStomatitis,\n\tmicrocytic\tanemia,\tmalaise\nMagnesium\nAlcoholism,\tdiuretics\nNeuromuscular\tirritability,\thypokalemia,\thypocalcemia\nPhosphorus\nAnabolism,\talcoholism\nAnorexia,\twe...
[ 0.026141725480556488, -0.08902020752429962, 0.00419158861041069, 0.006993975955992937, -0.059565119445323944, 0.013662843033671379, 0.04801958054304123, 0.07246679812669754, -0.07421977072954178, 0.041127197444438934, 0.015801914036273956, 0.006258912850171328, 0.0651690661907196, 0.016842...
Anorexia,\tweakness,\tcardiac\tfailure,\tglucose\tintolerance\nZinc\nDiarrhea,\tdiuretics,\nalcoholism\nImmunodeficiency,\timpaired\ttaste\tacuity,\tdelayed\twound\thealing,\timpaired\nprotein\tsynthesis\nDeficiencies\tof\tfat-soluble\tvitamins\thave\tbeen\tfound\tin\n\tall\ttypes\tof\tliver\tfailure,\tespecially\tin\t...
[ 0.03332243859767914, -0.10276556760072708, 0.04243585467338562, 0.05446362495422363, -0.14242751896381378, -0.02454599365592003, 0.05669693276286125, 0.031314555555582047, -0.10751637816429138, 0.06132303178310394, 0.06469901651144028, -0.06445550173521042, 0.021598832681775093, 0.02343704...
all\ttypes\tof\tliver\tfailure,\tespecially\tin\tcholestatic\tdiseases\tin\nwhich\tmalabsorption\tand\tsteatorrhea\toccur.\tImpaired\tdark\tadaptation\tcan\toccur\tfrom\tvitamin\tA\tdeficiency.\tHepatic\nosteodystrophy\tor\tosteopenia\tcan\tdevelop\tfrom\tvitamin\tD\tdeficiency.\tTherefore\tsupplementation\tis\tnecessa...
[ 0.010087869130074978, -0.10446090996265411, 0.05033257603645325, -0.01412348821759224, -0.0979958027601242, -0.027445146813988686, 0.07645964622497559, 0.027283750474452972, -0.01894981414079666, 0.06636717170476913, 0.10074300318956375, -0.031066104769706726, 0.0010305913165211678, 0.0519...
may\trequire\tusing\twater-miscible\tforms\tof\tfat\tsoluble\tvitamins.\tIntravenous\tor\tintramuscular\tvitamin\tK\toften\n\tis\tgiven\nfor\t3\tdays\tto\trule\tout\tvitamin\tK\tdeficiency\tas\tthe\tcause\tof\ta\tprolonged\tprothrombin\ttime.\tWater-soluble\tvitamin\ndeficiencies\tassociated\twith\tliver\tdisease\tincl...
[ -0.03923798352479935, -0.10248781740665436, 0.04536513239145279, -0.058758605271577835, -0.04633110389113426, -0.008760661818087101, 0.047892991453409195, 0.09225542098283768, -0.04213584586977959, 0.029917940497398376, 0.08206897974014282, -0.015300653874874115, 0.055870480835437775, 0.11...
Wernicke\tencephalopathy\n),\tpyridoxine\n(B\n6\n),\tcyanocobalamin\t(B\n12\n),\tfolate,\tand\tniacin\t(B\n3\n).\tLarge\tdoses\t(100\tmg)\tof\tthiamin\tare\tgiven\tdaily\tfor\ta\tlimited\ttime\nif\tdeficiency\tis\tsuspected\t(see\t\nAppendices\t12\n\tand\t\n13\n).\nMineral\tnutriture\talso\tis\taltered\tin\tliver\tdise...
[ -0.025852501392364502, -0.061869408935308456, -0.004123551305383444, 0.003738017287105322, -0.11444926261901855, 0.021740205585956573, 0.06349048018455505, 0.07809664309024811, -0.034154366701841354, 0.018310224637389183, 0.06858184188604355, -0.04232797026634216, 0.019380716606974602, 0.0...
gastrointestinal\tbleeding;\thowever,\tiron\tsupplementation\tshould\tbe\tavoided\tby\tpersons\twith\themochromatosis\tor\nhemosiderosis\t(see\t\nChapter\t31\n).\tManganese\tdeposition\thas\tbeen\tnoted\tto\taccumulate\tin\tbrains\tof\tpatients\twith\ncirrhosis,\tleading\tto\timpaired\tmotor\tfunction\tand\tparkinsonis...
[ -0.010609420016407967, -0.0930531844496727, 0.025400491431355476, -0.0065329959616065025, -0.12240835279226303, -0.013918381184339523, 0.05430615320801735, 0.08356865495443344, -0.035280436277389526, 0.05545646324753761, 0.07821382582187653, 0.029411017894744873, 0.018023112788796425, 0.04...
and\tincreased\toccurrence\tof\thepatic\tencephalopathy\n(\nButterworth,\t2013\n;\t\nKobtan\tet\tal,\t2016\n;\t\nSureka\tet\tal,\t2015\n).\tElevated\tserum\tcopper\tlevels\tare\tfound\tin\tcholestatic\nliver\tdiseases\t(i.e.,\tPBC\tand\tPSC).\nIn\tWilson’s\tdisease,\texcess\tcopper\tin\tvarious\torgans\tcauses\tsevere\...
[ -0.015083270147442818, -0.03560792654752731, 0.05403132364153862, -0.03888696804642677, -0.10589185357093811, 0.011488878168165684, 0.09085910022258759, 0.0031616396736353636, -0.018426459282636642, 0.03196236491203308, 0.11358679831027985, -0.09315700829029083, 0.033778898417949677, 0.042...
administration\tof\toral\tchelating\tagents\tsuch\tas\td-penicillamine,\ttrientine,\tor\ttetrathiomolybdate.\n\tZinc\tacetate\tcan\nblock\tabsorption\tof\tcopper\tfrom\tfood\tbut\ttypically\tis\tused\twith\tone\tof\tthe\tchelating\tdrugs.\tDietary\tcopper\trestriction
[ 0.009680998511612415, -0.08314359188079834, -0.04317375272512436, -0.05920559540390968, -0.08705221116542816, 0.0279222521930933, 0.09313835203647614, 0.03740432858467102, -0.0076465425081551075, 0.07080013304948807, 0.07324010878801346, -0.03754400089383125, 0.05921097844839096, 0.0324039...
can\tbe\tuseful\tduring\tinitial\ttherapy.\tCopper\talso\tcan\tbe\tpresent\tin\twater\twhere\tcopper\tpipes\tare\tused.\tRunning\ttap\nwater\tfor\tseveral\tseconds\tbefore\tusing\tthe\twater\tcan\treduce\tcopper\tconcentrations.\nZinc\tand\tmagnesium\tlevels\tare\tlow\tin\tliver\tdisease\trelated\tto\n\talcoholism\tand...
[ 0.0009011180372908711, -0.058949559926986694, 0.053490400314331055, -0.04033687710762024, -0.07307039201259613, -0.034992191940546036, 0.0778336152434349, -0.04113530367612839, -0.006794651970267296, 0.02489289455115795, 0.06559193134307861, -0.07534473389387131, 0.02723141387104988, 0.045...
alcoholism\tand\tdiuretic\ttherapy.\tCalcium,\tas\twell\tas\nmagnesium\tand\tzinc,\tmay\tbe\tmalabsorbed\twith\tsteatorrhea.\tTherefore\tthe\tpatient\tshould\ttake\tsupplements\tof\tthese\nminerals\tat\tleast\tat\tthe\tlevel\tof\tthe\tDRI.\nHerbal\tand\tdietary\tsupplements\tand\tliver\tdisease
[ 0.03021077811717987, -0.04498608410358429, 0.06393255293369293, 0.0005721441120840609, -0.03582320734858513, 0.013656305149197578, 0.08877406269311905, -0.06344087421894073, -0.03081352449953556, 0.01923767291009426, 0.08771681040525436, -0.04797806218266487, 0.0017287760274484754, 0.00757...
Herbal\tand\tdietary\tsupplements\tand\tliver\tdisease\nHepatotoxicity\tis\tone\tof\tthe\tgreatest\tconcerns\tassociated\twith\therbal\tand\tdietary\tsupplementation.\tWhile\tmost\nculinary\therbs\tare\tsafe,\n\tthere\tare\tcase\treports\tof\tsome\therbal\tsupplements\tresulting\tin\tliver\tfailure\t(\nBox\t28.3\n).\tO...
[ 0.012537600472569466, -0.02658398263156414, 0.061250925064086914, -0.008753638714551926, -0.05303521826863289, 0.03703439235687256, 0.09263049066066742, 0.010114789009094238, -0.006825566757470369, 0.06511890888214111, 0.07697020471096039, 0.020516114309430122, 0.00522598484531045, -0.0260...
Box\t28.3\n).\tOne\nreview\tlists\tmore\tthan\t150\therbal\tproducts\tthat\thave\tbeen\treported\tas\ta\tcause\tof\thepatotoxicity\t(\nTeschke\tet\tal,\n2013\n).\tThis\textensive\tlist\temphasizes\tthe\tgravity\tof\tthe\tpotential\tfor\tharm\tto\tthe\tliver\tfrom\tsome\therbal\tproducts,\tso\npractitioners\tshould\tbe\...
[ -0.006430956535041332, -0.049193739891052246, 0.013150879181921482, -0.04476248845458031, -0.0832040086388588, 0.029303720220923424, 0.08318134397268295, 0.02634907327592373, -0.005993808154016733, 0.03847179561853409, 0.08666488528251648, -0.004836949519813061, 0.039739515632390976, 0.014...
BOX\t28.3\nSelected\tHerbal\tSupplements\tAssociated\tWith\tHepatotoxicity\nBaikal\tskullcap\t(\nScutellaria\n)\nChaparral\t(\nLarrea\ttridentate\n)\nPyrrolizidine\talkaloids\t(found\tin\therbs\tof\tthe\t\nCompositae,\tLeguminosae,\tBoraginaceae\n\tfamily)\nComfrey\t(\nSymphytum\tofficinale\n)\nHeliotropium\nCrotalaria...
[ -0.033847298473119736, -0.01541824359446764, 0.026648737490177155, 0.012344986200332642, -0.041006509214639664, 0.015669051557779312, -0.021175425499677658, -0.030831418931484222, 0.03406960144639015, 0.08400463312864304, 0.15208867192268372, -0.0699029192328453, -0.011976507492363453, 0.0...
Crotalaria\nGermander\t(\nTeucrium\tchamaedrys\n)\nGreater\tcelandine\t(\nChelidonium\tmajus\n)\nSaw\tpalmetto\t(\nSerenoa\trepens\n)\nNoni\n\tjuice\t(\nMorinda\tcitrifolia\n)\nMargosa\toil\t(\nAntelaea\tazadirachta\n)\nAloe\tvera\t(aloe\tlatex)\nBlack\tcohosh\t(\nActea\tracemosa\n\tor\t\nActea\tcimicifuga\n)
[ -0.05720973014831543, -0.027450283989310265, 0.025700872763991356, -0.03304848447442055, -0.03548170253634453, 0.03445371612906456, 0.009194734506309032, -0.001907676924020052, -0.006957675330340862, 0.042385220527648926, 0.1369583159685135, -0.08897104114294052, -0.015437372028827667, -0....
LipoKinetix\t(\nusnic\tacid\n)\nAtractylis\tgummifera\nImpila\t(\nCallilepis\tlaureola\n)\nMistletoe\t(\nViscum\talbum\n)\nValerian\t(\nValerian\tofficinalis\n)\nSenna\t(\nCassia\tangustifolia\n)\nPennyroyal\t(squaw\tmint\toil)\nKava\t(\nPiper\tmethysticum\n)\nLiatris\tcallilepis\nGreen\ttea\textract\n\t(\nCamellia\tsi...
[ -0.047351446002721786, -0.07536143809556961, 0.027880007401108742, -0.018933501094579697, -0.11877425014972687, 0.024885954335331917, 0.027291985228657722, -0.023826327174901962, 0.005018420051783323, 0.052880413830280304, 0.15553167462348938, -0.08374952524900436, -0.021857233718037605, 0...
),\talthough\tgreen\ttea\tin\treasonable\tamounts\tappears\tsafe\nCascara\tsagrada\nOxyElite\tPro\nJin\tBu\tHuan\t(\nLycopodium\tserratum\n)\nMa\tHuang\t(\nEphedra\tsinica\n)\nDai-saiko-to\t(\nSho-saiko-to\n)\nHydroxycut\nLipoKinetix\t(Syntrax\tInnovations,\tInc,\tCape\tGirardeau,\tMO),\tOxyElite\tPro\t(USP\tLabs,\tLLC...
[ -0.05792215093970299, -0.08151674270629883, 0.02417280524969101, -0.03757864609360695, -0.10232503712177277, 0.01272859051823616, 0.08989007025957108, 0.03671455755829811, 0.039980389177799225, 0.0336582213640213, 0.11816789209842682, 0.005655296146869659, 0.012113140895962715, 0.022735698...
Health\tSciences\tUSA,\tInc,\tBlasdell,\tNY).\t\nReprinted\twith\tpermission\n\tfrom:\tCorey\tRL,\tRakela\tJ:\tComplementary\tand\talternative\tmedicine:\trisks\tand\tspecial\nconsiderations\tin\tpre-\tand\tpost-transplant\tpatients,\t\nNutr\tClin\tPract\n\t29:322,\t2014.\nOther\tdietary\tproducts\talso\thave\tbeen\tim...
[ -0.05160326510667801, -0.0013543486129492521, 0.021314166486263275, -0.04344338923692703, -0.09317275881767273, 0.008327946066856384, 0.08403027057647705, 0.06369692087173462, -0.02877659909427166, -0.01684316247701645, 0.0961955115199089, -0.03532951697707176, 0.013942886143922806, -0.016...
cambogia,\tHerbalife\tproducts,\tHydroxycut,\tand\tOxyElite\tPro\t(\nCrescioli\tet\tal,\t2018\n;\t\nCenters\tfor\tDisease\tControl\tand\nPrevention\t[CDC],\t2013\n;\t\nFong\tet\tal,\t2010\n;\t\nJóhannsson\tet\tal,\t2010\n;\t\nSchoepfer\tet\tal,\t2007\n;\t\nSharma\tet\tal,\t2010\n).\tOne\tof
[ -0.07126250118017197, 0.013640249148011208, 0.02115362510085106, -0.095569908618927, -0.04512923210859299, 0.03651222214102745, 0.07693943381309509, 0.04445798322558403, 0.03728630766272545, 0.05188712477684021, 0.12877324223518372, -0.021807659417390823, 0.018834056332707405, 0.0066778259...
;\t\nSchoepfer\tet\tal,\t2007\n;\t\nSharma\tet\tal,\t2010\n).\tOne\tof\nthe\tmost\tsignificant\tevents\toccurred\tin\t2013\twhen\t56\tindividuals\t(43\tin\tHawaii)\ttaking\tOxyElite\tPro\tdeveloped\tacute\nor\tfulminant\tliver\tfailure.\tSeveral\tpatients\trequired\tliver\ttransplantation\tand\tat\tleast\tone\tpatient\...
[ 0.0019291474018245935, -0.03331650421023369, 0.008240656927227974, -0.06339332461357117, -0.09040437638759613, 0.010782264173030853, 0.059649545699357986, 0.047212228178977966, 0.014285391196608543, 0.019991811364889145, 0.12749655544757843, -0.0011175371473655105, 0.06622270494699478, 0.0...
CDC,\t2013\n;\nFood\tand\tDrug\tAdministration\t[FDA],\t2014\n).\nDespite\treports\tof\thepatotoxicity\n\twith\tnumerous\therbal\tsupplements,\tsome\tsupplements\thave\tbeen\tinvestigated\tfor\nbenefits\ton\tliver\tdisease.\t\nS\n-adenosyl-\nL\n-methionine\t(SAMe)\tis\tsometimes\tsuggested\tfor\tuse\twith\tliver\tdisea...
[ -0.01866363175213337, -0.06343646347522736, 0.029451169073581696, -0.04996801167726517, -0.03671780228614807, 0.024544181302189827, 0.07825162261724472, 0.08978940546512604, 0.018084071576595306, 0.05549938604235649, 0.09718414396047592, -0.011133494786918163, 0.020016878843307495, 0.01944...
purported\tto\tact\tas\ta\tmethyl\tdonor\tfor\tmethylation\treactions\tand\tparticipates\tin\tglutathione\tsynthesis\t(an\nantioxidant).\tA\trecent\tsystematic\treview\tand\tmeta-analysis\tsuggested\tSAMe\tmay\timprove\tliver\tfunction\n\tbut\tdoes\tnot\nimprove\toutcomes\tfor\tchronic\tliver\tdisease\t(\nGuo\tet\tal,\...
[ -0.04320022463798523, -0.019332749769091606, 0.012031453661620617, -0.039680059999227524, -0.05309751629829407, 0.013172131031751633, 0.053081948310136795, 0.04921066388487816, 0.03895235434174538, 0.11477664858102798, 0.12282849103212357, -0.04028693959116936, -0.0011809447314590216, 0.06...
Guo\tet\tal,\t2015\n).\tBetaine\thas\tbeen\tproposed\tfor\ttreatment\tof\tNASH,\nalcoholic\tliver\tdisease,\tand\tother\tconditions.\tBetaine\tfunctions\tin\tthe\tliver\tas\ta\tmethyl\tdonor.\tAlthough\tthere\tis\ntheoretical\tpromise,\tthere\tis\ta\tlack\tof\tstrong\tevidence\tfor\tbenefit\t(\nDay\tand\tKempson,\t2016...
[ -0.036762844771146774, 0.02219555713236332, 0.04368500038981438, -0.007634615991264582, -0.0678819864988327, 0.0072103226557374, 0.08132839947938919, -0.046271733939647675, 0.031962472945451736, 0.0428081676363945, 0.10132869333028793, -0.03722839802503586, 0.006947642657905817, 0.02097271...
Abdelmalek\tet\tal,\t2009\n;\nMukherjee,\t2011\n).\nMilk\tthistle\tappears\tto\n\tbe\tthe\tmost\tpopular\tand\textensively\tstudied\therbal\tsupplement\tfor\tliver\tdisease.\tThe\tactive\ncomponent\tin\tmilk\tthistle\tis\tsilymarin\twith\tsilybin\t(constituting\t50%\tto\t70%\tof\tsilymarin)\tbelieved\tto\thave\tthe\tmo...
[ 0.009084217250347137, 0.037883460521698, 0.03565889224410057, -0.0691627785563469, -0.09303891658782959, -0.016306418925523758, 0.05583116039633751, 0.000015035458091006149, 0.003577366005629301, 0.042623452842235565, 0.08678989112377167, -0.02354569174349308, 0.02949550934135914, -0.03040...
biologic\tactivity.\tMilk\tthistle\tis\tproposed\tto\thave\tantiinflammatory,\tantioxidant,\tand\tantifibrotic\tproperties,\twhich\nwould\tbe\tbeneficial\tin\tliver\tdisease\t(\nAbenavoli\tet\tal,\t2010\n).\tMilk\tthistle\n\thas\tbeen\tevaluated\tfor\tviral\thepatitis,
[ 0.028797704726457596, -0.06109362840652466, 0.030243640765547752, -0.03779337927699089, -0.07053025811910629, 0.030013596639037132, 0.07760930806398392, 0.05123055353760719, -0.035133957862854004, 0.07050924003124237, 0.07019325345754623, -0.03339960798621178, -0.028953827917575836, 0.0506...
).\tMilk\tthistle\n\thas\tbeen\tevaluated\tfor\tviral\thepatitis,\nalcoholic\tliver\tdisease,\tand\ttoxin-induced\tliver\tdisease.\tA\trecent\tmeta-analysis\tevaluated\tthe\tbenefits\tof\tsilymarin\ton\nNAFLD.\tThe\tstudy\tshowed\tthat\tsilymarin\tmay\treduce\ttransaminases,\tbut\tthere\twas\tno\tevaluation\tof\thistol...
[ 0.0041679441928863525, -0.035464536398649216, 0.06795721501111984, -0.03429452329874039, -0.09482445567846298, 0.014769489876925945, 0.044070053845644, 0.018090806901454926, 0.015571536496281624, 0.0710533931851387, 0.11246339976787567, -0.05472453311085701, 0.010618004016578197, 0.0498140...
changes\tin\tthe\tliver\t(\nZhong\tet\tal,\t2017\n).\tDespite\tits\tpopularity\tand\twidespread\tuse,\ta\tclear\tconsensus\tis\tlacking\tas\tto\na\tbeneficial\n\teffect\tof\tmilk\tthistle\ton\tall\tforms\tof\tliver\tdisease,\tso\tindividual\tassessment\tis\tneeded.\tHowever,\tdata\tare\nnot\tsufficient\tto\tsuggest\tth...
[ 0.009623344987630844, -0.03202638775110245, 0.08077755570411682, -0.0670425146818161, -0.10111208260059357, 0.026858126744627953, 0.046924542635679245, -0.01939643919467926, 0.020050613209605217, 0.02931646816432476, 0.1122080385684967, -0.021715430542826653, 0.024664128199219704, 0.001574...
Liver\tresection\tand\ttransplantation\nAs\twith\tany\tmajor\tsurgery,\tprotein\tand\tenergy\tneeds\tincrease\tafter\tliver\tresection.\tNeeds\talso\tare\tincreased\tfor\tliver\ncell\tregeneration.\tEN\tcan\tbe\tbeneficial\tby\n\tproviding\tportal\thepatotropic\tfactors\tnecessary\tfor\tliver\tcell\tproliferation.
[ -0.0014727846719324589, -0.043644677847623825, 0.0624132938683033, -0.04353455454111099, -0.07005485892295837, -0.0014028842560946941, 0.09303637593984604, 0.06340274214744568, -0.06947116553783417, 0.04865792393684387, 0.11958830803632736, -0.027311474084854126, -0.002684336621314287, 0.0...
Optimal\tnutrition\tis\tmost\timportant\tfor\tpatients\twith\tpoor\tnutrition\tstatus\tbefore\thepatectomy\t(e.g.,\tpatients\twith\ncholangiocarcinoma).\nLiver\ttransplantation\thas\tbecome\tan\testablished\ttreatment\tfor\tESLD.\tMalnutrition\tis\tcommon\tin\tliver\ttransplant\ncandidates.\tDietary\tintake\toften\tcan...
[ 0.03061561845242977, -0.008519050665199757, 0.03466618433594704, -0.03753018379211426, -0.09390687197446823, -0.021974200382828712, 0.05724869295954704, 0.09941774606704712, -0.012405293062329292, 0.020904801785945892, 0.08123188465833664, 0.04629898816347122, 0.06428669393062592, 0.054534...
frequent,\tnutrient-dense\tmeals,\tand\toral\nnutritional\tsupplements\talso\tmay\tbe\twell\ttolerated.\tEN\tis\tindicated\twhen\toral\tintake\tis\tinadequate\tor\ncontraindicated.\tVarices\tare\tnot\tan\tabsolute\tcontraindication\tfor\tplacement\tof\ta\tfeeding\ttube.\tBecause\tPN\tcan\taffect
[ 0.03394392877817154, -0.060241322964429855, 0.05330083146691322, 0.01831289380788803, -0.06732222437858582, 0.03480316698551178, 0.127430722117424, -0.02923618257045746, 0.001112428610213101, 0.03319668024778366, 0.10893847793340683, -0.03785828500986099, 0.033662181347608566, 0.0430488474...
liver\tfunction\tadversely,\tEN\tis\tpreferred.\tPN\tis\treserved\tfor\tpatients\twithout\tadequate\tgut\tfunction\t(see\t\nChapter\t12\n).\nIn\tthe\tacute\tposttransplant\n\tphase,\tnutrient\tneeds\tare\tincreased\tto\tpromote\thealing,\tdeter\tinfection,\tprovide\tenergy
[ 0.004863324575126171, -0.05070158839225769, 0.05926761031150818, -0.037738461047410965, -0.07902276515960693, 0.019806863740086555, 0.06862010806798935, 0.12571370601654053, -0.06818145513534546, 0.04904292896389961, 0.0915025845170021, -0.02944354899227619, 0.014431222341954708, 0.0578031...
for\trecovery,\tand\treplenish\tdepleted\tbody\tstores.\tNitrogen\trequirements\tare\televated\tin\tthe\tacute\tposttransplant\nphase\tand\tcan\tbe\tmet\twith\tearly\tpostoperative\tEN.\tEarly\tpostoperative\tEN\thas\tbeen\tassociated\twith\treduced\ninfections\tin\tliver\ttransplant\trecipients\t(\nHasse\tet\tal,\t199...
[ -0.024384697899222374, -0.015744060277938843, 0.08500541001558304, -0.08425714820623398, -0.11134764552116394, 0.010970424860715866, 0.10984811186790466, 0.02823498845100403, -0.017389865592122078, 0.05116729438304901, 0.1106988787651062, 0.009938232600688934, 0.007606898434460163, 0.01864...
;\t\nIkegami\tet\tal,\t2012\n;\t\nMasuda\tet\tal,\t2014\n).\tAdministration\nof\tprobiotics\tand\tfiber\twith\ttube\tfeeding\tmay\treduce\tpostoperative\tinfection\trate\tbetter\tthan\ttube\tfeeding\tor\tfiber\nalone\t(\nRayes\tet\tal,\t2005\n).\nMultiple\tmedications\tused\tafter\ttransplant\thave\tnutritional\tside\t...
[ 0.011417921632528305, -0.08521515876054764, 0.06373465061187744, -0.01868371106684208, -0.08976493030786514, 0.0007423887145705521, 0.08417011797428131, 0.02065509371459484, -0.036119718104600906, 0.03799568861722946, 0.12262669205665588, 0.015849994495511055, 0.02073957957327366, 0.009553...
hypercatabolism,\tdiarrhea,\thyperglycemia,\thyperlipidemia,\tsodium\tretention,\thypertension,\thyperkalemia,\tand\nhypercalciuria.\n\tTherefore\tdietary\tmodification\tis\tbased\ton\tthe\tspecific\tside\teffects\tof\tdrug\ttherapy\t(\nTable\t28.5\n).\nDuring\tthe\tposttransplant\tphase,\tnutrient\trequirements\tare\t...
[ -0.004097583703696728, -0.06888898462057114, 0.01648404635488987, 0.007420820649713278, -0.04663380980491638, 0.04712639003992081, 0.06962559372186661, 0.05143411085009575, -0.04809733107686043, 0.03471911698579788, 0.08615034818649292, -0.012122060172259808, 0.06839592754840851, -0.011459...
hyperlipidemia,\thypertension,\tdiabetes\tmellitus,\tand\tosteopenia.\t\nTable\t28.6\n\tsummarizes\tnutrient\tneeds\tafter\tliver\ntransplantation.
[ -0.003740952117368579, -0.025799499824643135, -0.023936353623867035, 0.03272165358066559, -0.006056873127818108, 0.06735074520111084, 0.05581776425242424, 0.062004879117012024, -0.0371374636888504, 0.007790852338075638, 0.08673027902841568, 0.01827891729772091, -0.0010882922215387225, -0.0...
TABLE\t28.5\nDrugs\tCommonly\tUsed\tAfter\tLiver\tTransplantation\nImmunosuppressant\tDrug\nPossible\tNutritional\tSide\tEffects\nProposed\tNutrition\tTherapy\nAzathioprine\nMacrocytic\tanemia\nMouth\tsores\nNausea,\tvomiting,\tdiarrhea,\tanorexia,\tsore\nthroat,\tstomach\tpain,\tdecreased\ttaste\nacuity\nGive\tfolate\...
[ 0.03561967611312866, -0.08853040635585785, 0.003297597635537386, 0.03723917156457901, -0.09314583241939545, 0.016279932111501694, 0.0960235521197319, 0.051633141934871674, -0.0946928858757019, 0.0425448901951313, 0.07907245308160782, -0.015673115849494934, 0.021159226074814796, 0.002982175...
Adjust\tfood\tand\tmeals\tas\tneeded;\nmonitor\tintake.\nAntithymocyte\tglobulin\t(ATG),\nlymphocyte\timmune\tglobulin\nNausea,\tvomiting\nAdjust\tfood\tand\tmeals\n\tas\tneeded;\nmonitor\tintake.\nCyclosporine\nSodium\tretention\nDecrease\tsodium\tintake.\nHyperkalemia\nDecrease\tpotassium\tintake.\nHyperlipidemia\nLi...
[ 0.012230361811816692, -0.09304413199424744, -0.002035984769463539, 0.027361422777175903, -0.06293243169784546, 0.013254600577056408, 0.116644486784935, 0.08639019727706909, -0.0856565460562706, 0.04234975948929787, 0.06784316152334213, -0.04599761962890625, 0.03697512671351433, 0.046315502...
Limit\tfat\tand\tsimple\tcarbohydrate\nintake.\nHyperglycemia\nDecrease\tsimple\tcarbohydrate\tintake.\nDecreased\tserum\tmagnesium\tlevel\nIncrease\tmagnesium\tintake;\tgive\nsupplements.\nHypertension\nLimit\tsodium\tintake.\nNausea,\tvomiting\nAdjust\tfood\tand\tmeals\n\tas\tneeded;\nmonitor\tintake.\nGlucocorticoid...
[ -0.007705709431320429, -0.08568644523620605, 0.013086126185953617, 0.03071657568216324, -0.032105494290590286, 0.01467994786798954, 0.09796539694070816, 0.08032099157571793, -0.0765371099114418, 0.026224249973893166, 0.054084692150354385, -0.02351422980427742, 0.024339891970157623, 0.03585...
Sodium\tretention\nDecrease\tsodium\tintake.\nHyperglycemia\nDecrease\tsimple\tcarbohydrate\tintake.\nHyperlipidemia\nLimit\tfat\tand\tsimple\tcarbohydrate\nintake.\nFalse\thunger\nAvoid\tovereating.\nProtein\twasting\twith\thigh\tdoses\nIncrease\tprotein\tintake.\nDecreased\tabsorption\tof\tcalcium\tand\tphosphorus\nI...
[ -0.0024348299484699965, -0.09891591221094131, 0.059282343834638596, 0.0005331752472557127, -0.053062453866004944, 0.02460777759552002, 0.13632899522781372, 0.04078515246510506, -0.06635569781064987, 0.062227003276348114, 0.03231814503669739, -0.04448731616139412, 0.05669420212507248, 0.030...
Increase\tcalcium\tand\tphosphorus\nintake;\tgive\tsupplements\n\tas\nneeded.\nMycophenolate\tmofetil,\nmycophenolic\tacid\nNausea,\tvomiting,\tdiarrhea\nAdjust\tfood\tand\tmeals\tas\tneeded;\nmonitor\tintake.\nSirolimus\nPossible\tGI\tsymptoms\nAdjust\tfood\tand\tmeals\tas\tneeded;\nmonitor\tintake.\nHyperlipidemia\nL...
[ 0.029526911675930023, -0.06930624693632126, 0.014675759710371494, 0.014843068085610867, -0.04760335385799408, 0.04262937605381012, 0.10203942656517029, 0.06577161699533463, -0.04923872649669647, 0.042729441076517105, 0.09614324569702148, -0.04786568507552147, 0.020786184817552567, 0.013206...
Limit\tfat\tand\tsimple\tcarbohydrate\nintake.\nInhibits\twound\thealing\nEnsure\tadequate\tmacro-\tand\nmicronutrients.\nDepressed\tappetite.\nConsider\tappetite\tstimulants.\nTacrolimus\nHyperglycemia\nDecrease\tsimple\tcarbohydrate\tintake.\nHyperkalemia\nDecrease\tpotassium\tintake.\nNausea,\tvomiting\nAdjust\tfood...
[ -0.003104135161265731, -0.08733775466680527, 0.040981847792863846, 0.033960551023483276, -0.08320695906877518, 0.00745869055390358, 0.11624433845281601, 0.046883001923561096, -0.06397442519664764, 0.028981253504753113, 0.09165065735578537, -0.06880628317594528, 0.02031542733311653, 0.04066...
TABLE\t28.6\nGeneral\tNutrient\tRequirements\tfor\tLiver\tTransplant\tPatients\nPretransplantation\nImmediate\tPosttransplantation\n(First\t2\tPosttransplant\nMonths)\nLong-Term\tPosttransplantation\n*\nProtein\nDependent\ton\tnutrition\tstatus\tand\nmedical\tcondition\tbut\tusually\t1-\n1.5\tg/kg\nDependent\ton\tnutri...
[ 0.0015534126432612538, -0.03705456107854843, 0.019394222646951675, -0.011691535823047161, -0.15849502384662628, -0.028175529092550278, 0.03640836477279663, 0.07254980504512787, -0.022945795208215714, 0.020710259675979614, 0.08857924491167068, -0.0321362130343914, -0.004171945154666901, 0.0...
Dependent\ton\tnutrition\tstatus,\nmedical\tcondition,\tand\tdialysis\nrequirement\tbut\tusually\t1.2-2\ng/kg\nMaintenance\t–\tabout\t1\tg/kg\n*\nCalories\nDependent\ton\tnutrition\tstatus\tand\nlosses;\tusually\t20%-50%\n\tabove\nbasal\nDependent\ton\tnutrition\tstatus\tand\nmetabolic\tstress\tbut\tusually\n20%-30%\ta...
[ 0.005302478093653917, -0.03970041126012802, 0.02599167264997959, 0.03367890045046806, -0.1479324847459793, -0.012159411795437336, 0.06672628223896027, 0.03908758610486984, -0.0641140416264534, 0.027813680469989777, 0.10147786885499954, -0.06436538696289062, -0.0007717192638665438, 0.025232...
20%-30%\tabove\tbasal\nDependent\ton\tactivity\tand\tweight\ngoals;\tusually\t20%\tabove\tbasal\nfor\tsedentary\tactivity\tif\tat\tgoal\nweight\nFat\nAs\tneeded\nApproximately\t30%\tof\tcalories\nModerate\tfat\t(30%\tof\tcalories)\nCarbohydrate\nReduced\tcarbohydrate\tif\tdiabetes\nor\tobesity\tpresent\nReduced\tcarboh...
[ 0.03021976910531521, -0.0964733138680458, 0.03314549848437309, 0.08380720019340515, -0.08596907556056976, -0.01516394317150116, 0.08977183699607849, -0.004355794284492731, -0.04297850653529167, 0.03504214063286781, 0.057073794305324554, -0.06550762802362442, -0.00564977340400219, 0.0453493...
present\nReduced\tsimple\n\tcarbohydrate,\nespecially\tif\tdiabetes\tor\tobesity\npresent\nSodium\n2\tg/day\n2\tg/day\t(as\tindicated)\n2\tg/day\t(as\tindicated)\nFluid\nRestrict\tto\t1000-1500\tmL/day\t(if\nhyponatremic)\nAs\tneeded\nAs\tneeded\nCalcium\n800-1200\tmg/day\n800-1200\tmg/day\n1200-1500\tmg/day\nVitamins\...
[ -0.0352201946079731, -0.02771553210914135, 0.058454398065805435, 0.025461038574576378, -0.04635665565729141, -0.05971956253051758, 0.06984489411115646, 0.07843175530433655, -0.0794643759727478, -0.008873643353581429, 0.08009932190179825, -0.08635738492012024, 0.053450096398591995, 0.036109...
Vitamins\nMultivitamin/mineral\nsupplementation\tto\tDRI\tlevels;\nadditional\twater-\tand\tfat-soluble\nvitamins\tas\tindicated\nMultivitamin/mineral\nsupplementation\n\tto\tDRI\tlevels;\nadditional\twater-\tand\tfat-soluble\nvitamins\tas\tindicated\nMultivitamin/mineral\nsupplementation\tto\tDRI\tlevels\nDRI\n,\tDiet...
[ -0.032441962510347366, -0.06663907319307327, 0.06952572613954544, 0.0021157851442694664, 0.004627809394150972, -0.0003595092275645584, 0.06295763701200485, 0.0458805188536644, -0.11353561282157898, -0.0006131297559477389, 0.08915489912033081, -0.0458994135260582, 0.04664158448576927, 0.007...
DRI\n,\tDietary\treference\tintake.\n*\nUse\testimated\tdry\tor\tideal\tweight.\nPhysiology\tand\tfunctions\tof\tthe\tgallbladder\nThe\tgallbladder\tlies\ton\tthe\tundersurface\tof\tthe\tright\tlobe\tof\tthe\tliver\t(\nFig.\t28.6\n).\tThe\tmain\tfunction\tof\tthe\tgallbladder\nis\tto\tconcentrate,\tstore,\tand
[ 0.0033321287482976913, -0.07918843626976013, 0.08171968907117844, -0.04350126534700394, -0.15099282562732697, -0.06346313655376434, 0.07100541144609451, 0.04061131551861763, -0.014672700315713882, 0.01404957938939333, 0.07410081475973129, -0.07868534326553345, 0.001095545245334506, 0.04468...
).\tThe\tmain\tfunction\tof\tthe\tgallbladder\nis\tto\tconcentrate,\tstore,\tand\n\texcrete\tbile,\twhich\tis\tproduced\tby\tthe\tliver.\tDuring\tthe\tconcentration\tprocess,\twater\tand\nelectrolytes\tare\tresorbed\tby\tthe\tgallbladder\tmucosa.\tBile\tis\tcomposed\tof\tbile\tsalts\tand\texcretory\tendogenous\tand
[ 0.02136066183447838, -0.07225663959980011, 0.07051355391740799, -0.01565636694431305, -0.12632621824741364, -0.03952940180897713, 0.08909048140048981, 0.020286116749048233, 0.024020176380872726, 0.026983099058270454, 0.07895702868700027, -0.02995642088353634, 0.033156029880046844, 0.047077...
exogenous\tcompounds.\tOther\tcomponents\tinclude\tfatty\tacids,\tcholesterol,\tphospholipids,\tbilirubin,\tprotein,\tand\nother\tcompounds.\tBile\tsalts\tare\tmade\tby\tliver\tcells\tfrom\tcholesterol\tand\tare\tessential\n\tfor\tthe\tdigestion\tand\nabsorption\tof\tfats,\tfat-soluble\tvitamins,\tand\tsome\tminerals\t...
[ -0.047218263149261475, -0.10546711832284927, -0.004711724352091551, -0.0014994227094575763, -0.04555613920092583, 0.013812010176479816, 0.059652622789144516, 0.05988980084657669, 0.001926058204844594, 0.01285755354911089, 0.0906168594956398, -0.02330058068037033, 0.031973131000995636, 0.03...
Chapter\t1\n).\tBilirubin,\tthe\tmain\tbile\tpigment,\tis\nderived\tfrom\tthe\trelease\tof\themoglobin\tfrom\tred\tblood\tcell\tdestruction.\tIt\tis\ttransported\tto\tthe\tliver,\twhere\tit\tis\nconjugated\tand\texcreted\tvia\tbile.\nFIG.\t28.6\nSchematic\tdrawing\tshowing\trelationship\tof\torgans\tof\tthe\tupper\tabd...
[ -0.023589884862303734, -0.055223479866981506, 0.013033677823841572, -0.09267869591712952, -0.11880793422460556, 0.019725298509001732, 0.05424622446298599, 0.0341029055416584, 0.005688817705959082, 0.0792330950498581, 0.10725931078195572, 0.05803114175796509, 0.030114885419607162, -0.011290...
A,\n\tLiver\t(retracted\tupward);\t\nB,\n\tgallbladder;\t\nC,\nesophageal\topening\tof\tstomach;\t\nD,\n\tstomach\t(\nshown\tin\tdotted\toutline\n);\t\nE,\n\tcommon\tbile\tduct;\t\nF,\n\tduodenum;\t\nG,\n\tpancreas\tand\npancreatic\tduct;\t\nH,\n\tspleen;\t\nI,\n\tkidneys.\n\t\nSource:\n\t(Courtesy\tCleveland\tClinic,\...
[ -0.03142758086323738, -0.014176987111568451, 0.022114748135209084, -0.06876788288354874, -0.07781337201595306, 0.02856207825243473, 0.09628210961818695, -0.017234301194548607, 0.018184062093496323, 0.043682172894477844, 0.09063470363616943, -0.011386984959244728, 0.07232224196195602, 0.023...
The\tprimary\ttransporter\tresponsible\tfor\tbile\n\tsalt\tsecretion\tis\tthe\tbile\tsalt\texport\tpump\t(BSEP).\tOverall,\tbile\tsalts\nplay\ta\tkey\trole\tin\ta\twide\trange\tof\tphysiologic\tand\tpathophysiologic\tprocesses\t(\nKubitz\tet\tal,\t2012\n).\tExcreted\tinto\tthe
[ 0.02105424925684929, -0.026893792673945427, 0.054244399070739746, -0.043091729283332825, -0.0830213725566864, 0.011907210573554039, 0.10108361393213272, 0.050256967544555664, 0.03781895339488983, 0.023131676018238068, 0.09507621079683304, -0.012701943516731262, 0.021233059465885162, 0.0391...
Kubitz\tet\tal,\t2012\n).\tExcreted\tinto\tthe\nsmall\tintestine\tvia\tbile,\tbile\tsalts\tare\tlater\tresorbed\tinto\tthe\tportal\tsystem\t(enterohepatic\tcirculation).\tThis\tis\tthe\nprimary\texcretory\tpathway\tfor\tthe\tminerals\tcopper\tand\tmanganese.\nBile\tcontains\timmunoglobulins\n\tthat\tsupport\tthe\tinteg...
[ 0.030452899634838104, -0.05741124972701073, 0.04313588887453079, -0.044421106576919556, -0.15601877868175507, 0.00511675700545311, 0.07960726320743561, 0.01596207730472088, 0.018103932961821556, 0.07015370577573776, 0.09638641774654388, -0.03811156749725342, 0.02774856612086296, 0.03551955...
receptor\t(FGFR4)\tcontrols\tbile\tacid\tmetabolism\tand\tprotects\tthe\tliver\tfrom\tfibrosis;\tFGFR1\tand\tFGFR2\tassist\tin\nregeneration\tof\tthe\tliver\t(\nBöhm\tet\tal,\t2010\n).\tMolecular\tcrosstalk\tbetween\tbile\tacid–activated\tnuclear\treceptors\tand\nproinflammatory\tnuclear\tmediators\tprovides\tnew\tunde...
[ -0.011107925325632095, -0.10692007094621658, 0.007456747815012932, -0.017248762771487236, -0.05467946082353592, 0.0062184445559978485, 0.09891021251678467, 0.1037641391158104, 0.046919047832489014, 0.05552857369184494, 0.09660851210355759, -0.0032106470316648483, 0.03199980780482292, 0.100...
(\nKosters\tand\nKarpen,\t2010\n;\t\nLam\tet\tal,\t2010\n).\nBile\tis\tremoved\tby\tthe\tliver\tvia\tbile\tcanaliculi\tthat\tdrain\tinto\tintrahepatic\tbile\tducts.\tThe\tducts\tlead\tto\tthe\tleft\tand\nright\thepatic\tducts,\twhich\tleave\tthe\tliver\tand\tjoin\tto\tbecome\tthe\tcommon\thepatic\tduct.\tThe\tbile\tis\...
[ 0.025975724682211876, -0.039556801319122314, 0.033743251115083694, -0.0086542759090662, -0.10723914206027985, 0.006323246750980616, 0.09021489322185516, 0.04033081606030464, -0.013269178569316864, 0.06413936614990234, 0.11729591339826584, -0.02875019982457161, 0.005529386922717094, 0.05221...
gallbladder\tvia\tthe\tcystic\tduct\tfor\tconcentration\tand\tstorage.\tThe\tcystic\tduct\tjoins\tthe\tcommon\thepatic\tduct\tto\tform\nthe\tcommon\tbile\tduct.\tThe\tbile\tduct\tthen\tjoins\tthe\tpancreatic\tduct,\twhich\tcarries\tdigestive\tenzymes.\nDuring\tthe\tcourse\tof\tdigestion,\tfood\treaches\tthe\tduodenum,\...
[ 0.05184360593557358, -0.12694329023361206, 0.025124968960881233, 0.009440800175070763, -0.14035020768642426, -0.06720535457134247, 0.04071016237139702, 0.019451819360256195, -0.0009952590335160494, 0.01010159496217966, 0.08855260908603668, -0.010999003425240517, 0.03616414964199066, 0.0229...
cholecystokinin\t(CCK)\tand\tsecretin.\tThis\tstimulates\tthe\tgallbladder\tand\tpancreas\tand\tcauses\tthe\tsphincter\tof\tOddi\tto\nrelax,\tallowing\tpancreatic\tjuice\tand\tbile\tto\tflow\tinto\tthe\tduodenum\n\tat\tthe\tampulla\tof\tVater\tto\tassist\tin\tfat\tdigestion.\nFor\tthis\treason\tdiseases\tof\tthe\tgallb...
[ 0.01996592991054058, -0.09617302566766739, 0.033372946083545685, -0.0052353739738464355, -0.12303955852985382, -0.015057386830449104, 0.0837944969534874, 0.0283691193908453, 0.012393663637340069, 0.0009857636177912354, 0.10773371905088425, -0.031556449830532074, 0.039136141538619995, 0.018...
Diseases\tof\tthe\tgallbladder\nDisorders\tof\tthe\tbiliary\ttract\taffect\tmillions\tof\tpeople\teach\tyear,\tcausing\tsignificant\tsuffering\tand\teven\tdeath\tby\nprecipitating\tpancreatitis\tand\tsepsis.\tA\tdiverse\tspectrum\tof\tdisease\taffects\tthe\tbiliary\tsystem,\toften\tpresenting\n\twith
[ 0.03793107345700264, -0.08228648453950882, 0.029720323160290718, -0.005522170104086399, -0.10670474916696548, -0.0016263008583337069, 0.07051168382167816, 0.0043678670190274715, -0.04828675836324692, 0.05992585048079491, 0.08710653334856033, -0.011433937586843967, 0.014040689915418625, 0.0...
with\nsimilar\tclinical\tsigns\tand\tsymptoms.\tTreatment\tmay\tinvolve\tdiet,\tmedication,\tand/or\tsurgery.\nCholestasis\nPathophysiology\tand\tmedical\tmanagement\nCholestasis\n\tis\ta\tcondition\tin\twhich\tlittle\tor\tno\tbile\tis\tsecreted\tor\tthe\tflow\tof\tbile\tinto\tthe\tdigestive\ttract\tis
[ 0.049440111964941025, -0.04097358137369156, 0.05098605528473854, -0.008340935222804546, -0.10074404627084732, 0.00044368591625243425, 0.07858376950025558, 0.04057909548282623, 0.032515816390514374, 0.020222922787070274, 0.0468350425362587, 0.0011979187838733196, -0.0006088506779633462, 0.0...
obstructed.\tThis\tcan\toccur\tin\tpatients\twithout\toral\tor\tenteral\tfeeding\tfor\ta\tprolonged\tperiod,\tsuch\tas\tthose\trequiring\nPN,\tand\tcan\n\tpredispose\tto\t\nacalculous\tcholecystitis\n,\tan\tinflammatory\tdisease\tof\tthe\tgall\tbladder\twithout\tevidence\nof\tgallstones\tor\tcystic\tduct\tobstruction.\...
[ -0.0008652688702568412, -0.018413351848721504, 0.053715452551841736, -0.024669099599123, -0.1139601320028305, -0.02354331687092781, 0.10273811221122742, 0.0033055897802114487, 0.01645352691411972, 0.04609473794698715, 0.1167902871966362, 0.0020552510395646095, 0.06255361437797546, 0.056844...
hepatocytes\tinto\tbile.\tBSEP\tdeficiency\tresults\tin\tseveral\tdifferent\tgenetic\tforms\tof\tcholestasis\tand\tacquired\tforms\tof\ncholestasis\tsuch\tas\tdrug-induced\tcholestasis\tand\tintrahepatic\tcholestasis\n\tof\tpregnancy\t(\nLam\tet\tal,\t2010\n).\tPrevention
[ 0.004574335180222988, -0.04618602991104126, -0.005448526702821255, -0.020652594044804573, -0.09348052740097046, 0.04960234835743904, 0.0502474308013916, 0.0855923518538475, -0.022951671853661537, 0.09845484793186188, 0.05581418052315712, -0.03062601014971733, 0.0009444430470466614, 0.04393...
of\tpregnancy\t(\nLam\tet\tal,\t2010\n).\tPrevention\nof\tcholestasis\trequires\tstimulation\tof\tbiliary\tmotility\tand\tsecretions\tby\tat\tleast\tminimum\tenteral\tfeedings.\tIf\tthis\tis\nnot\tpossible,\tdrug\ttherapy\tis\tused.\nCholelithiasis\nPathophysiology\nThe\tformation\tof\tgallstones\t(\ncalculi\n)\tis\tkn...
[ 0.021303007379174232, -0.022349979728460312, 0.043694689869880676, 0.017107103019952774, -0.12388697266578674, 0.03289259970188141, 0.05111929029226303, 0.02749745361506939, 0.008762490004301071, 0.07305341213941574, 0.1199289858341217, -0.0485132560133934, -0.018115296959877014, 0.0112838...
The\tformation\tof\tgallstones\t(\ncalculi\n)\tis\tknown\tas\t\ncholelithiasis\n.\tVirtually\tall\tgallstones\tform\twithin\tthe\tgallbladder.\nGallstone\tdisease\taffects\tmillions\tof\tAmericans\n\teach\tyear\tand\tcan\tcause\tsignificant\thealth\trisks.\tIn\tmost\tcases
[ 0.0023319206666201353, -0.018343882635235786, 0.06896942853927612, -0.007281669415533543, -0.1728576272726059, -0.021562667563557625, 0.020362488925457, -0.021491337567567825, -0.00524373073130846, 0.044113434851169586, 0.10678793489933014, -0.09317557513713837, -0.03735831379890442, 0.016...
each\tyear\tand\tcan\tcause\tsignificant\thealth\trisks.\tIn\tmost\tcases\ngallstones\tare\tasymptomatic.\tGallstones\tthat\tpass\tfrom\tthe\tgallbladder\tinto\tthe\tcommon\tbile\tduct\tmay\tremain\tthere\nindefinitely\twithout\tcausing\tsymptoms,\tor\tthey\tmay\tpass\tinto\tthe\tduodenum\twith\tor\twithout\tsymptoms.\...
[ 0.029771916568279266, -0.00757431797683239, 0.07029252499341965, -0.034577708691358566, -0.1380641609430313, -0.054008178412914276, 0.03935128450393677, 0.003436625236645341, -0.026180880144238472, 0.05091575160622597, 0.09339019656181335, -0.058435212820768356, 0.03381381556391716, -0.001...
Choledocholithiasis\n\tdevelops\twhen\tstones\tslip\tinto\tthe\tbile\tducts,\tproducing\tobstruction,\tpain,\tand\tcramps.\tIf\npassage\n\tof\tbile\tinto\tthe\tduodenum\tis\tinterrupted,\t\ncholecystitis\n,\tinflammation\tof\tthe\tgallbladder,\tcan\tdevelop.\tIn\tthe
[ 0.020897239446640015, -0.12930990755558014, 0.06485608220100403, -0.008359940722584724, -0.15971994400024414, -0.06595097482204437, 0.06464419513940811, 0.023764746263623238, 0.0003601434000302106, -0.0005719576147384942, 0.10123524069786072, -0.013635953888297081, 0.024255836382508278, 0....
cholecystitis\n,\tinflammation\tof\tthe\tgallbladder,\tcan\tdevelop.\tIn\tthe\nabsence\tof\tbile\tin\tthe\tintestine,\tlipid\tabsorption\tis\timpaired,\tand\twithout\tbile\tpigments,\tstools\tbecome\tlight\tin\tcolor\n(acholic).\tIf\tuncorrected,\tbile\tbackup\tcan\tresult\tin\tjaundice\tand\tliver\tdamage\t(\nsecondar...
[ 0.027369841933250427, -0.12647183239459991, 0.05861001834273338, 0.003096346976235509, -0.15773038566112518, -0.0394071489572525, 0.09371539205312729, 0.010090437717735767, -0.0006091063260100782, 0.05372006446123123, 0.08825939893722534, -0.002371100476011634, 0.036166708916425705, 0.0351...
secondary\tbiliary\tcirrhosis\n).\nObstruction\tof\tthe\tdistal\tcommon\tbile\tduct\tcan\tlead\tto\tpancreatitis\n\tif\tthe\tpancreatic\tduct\tis\tblocked.\nMost\tgallstones\tare\tunpigmented\tcholesterol\tstones\tcomposed\tprimarily\tof\tcholesterol,\tbilirubin,\tand\tcalcium\tsalts.
[ -0.040111832320690155, -0.07740923017263412, 0.005894612520933151, -0.020901992917060852, -0.13355469703674316, -0.01878102496266365, 0.03519425168633461, 0.060678672045469284, 0.0031020159367471933, 0.019319705665111542, 0.1003812700510025, -0.024543792009353638, 0.01228802278637886, 0.03...
Bacteria\talso\tplay\ta\trole\tin\tgallstone\tformation.\tLow-grade\tchronic\tinfections\tproduce\tchanges\tin\tthe\tgallbladder\nmucosa,\twhich\taffect\tits\tabsorptive\tcapabilities.\tExcess\twater\tor\tbile\tacid\tmay\tbe\tabsorbed\tas\ta\tresult.\tCholesterol\nmay\tthen\tprecipitate\n\tout\tand\tcause\tgallstones\t...
[ -0.04429034888744354, -0.0674329400062561, 0.05992318317294121, -0.039261236786842346, -0.086068294942379, 0.0004464000812731683, 0.04228953644633293, 0.016439693048596382, -0.009912637993693352, 0.05299556255340576, 0.07792644947767258, -0.08280858397483826, 0.018553365021944046, 0.077369...
may\tthen\tprecipitate\n\tout\tand\tcause\tgallstones\t(\nNjeze,\t2013\n).\nThere\tare\tnumerous\trisk\tfactors\tthat\tmay\tpredispose\tan\tindividual\tto\tgallstone\tformation\t(\nStinton\tet\tal,\t2010\n).\nSome\tof\tthese\tare\tmodifiable,\tothers\tare\tnot\t(\nTable\t28.7\n)\tHigh\tdietary\tfat\tintake\tover\ta\tpr...
[ -0.019313514232635498, -0.009019413031637669, 0.09732300043106079, -0.015881318598985672, -0.059465836733579636, 0.020612923428416252, 0.08811049908399582, 0.015751605853438377, -0.04138679802417755, 0.0060699936002492905, 0.0909719243645668, -0.03368431702256203, 0.011694000102579594, 0.0...
Table\t28.7\n)\tHigh\tdietary\tfat\tintake\tover\ta\tprolonged\tperiod\tmay\npredispose\ta\tperson\tto\tgallstone\tformation\tbecause\tof\tthe\tconstant\tstimulus\tto\tproduce\tmore\tcholesterol\tfor\tbile\nsynthesis\trequired\tin\n\tfat\tdigestion.\tRapid\tweight\tloss\t(as\twith\tjejunoileal\tand\tgastric\tbypass\tsu...
[ -0.024586396291851997, -0.04754607751965523, 0.008874430321156979, 0.033477190881967545, -0.11912994831800461, 0.0047967517748475075, 0.023739852011203766, 0.03673135116696358, -0.021687543019652367, 0.008114338852465153, 0.07413964718580246, -0.032174162566661835, 0.012904500588774681, -0...
severe\tcalorie\trestriction)\tis\tassociated\twith\ta\thigh\tincidence\tof\tbiliary\tsludge\tand\tgallstone\tformation.\tIndeed,\ncholelithiasis\tand\tfatty\tliver\tdisease\tshare\trisk\tfactors,\tincluding\tcentral\tobesity,\tinsulin\tresistance,\tand\tdiabetes\nmellitus\t(\nKoller\tet\tal,\t2012\n;\t\nWeikert\tet\ta...
[ -0.007369296625256538, -0.0006831152713857591, 0.06763599812984467, -0.016092436388134956, -0.11178449541330338, -0.013094047084450722, 0.08029592037200928, 0.06781446933746338, -0.043149396777153015, 0.04184332862496376, 0.05528102442622185, -0.04321514070034027, 0.0031859807204455137, 0....
).\nTABLE\t28.7\nRisk\tFactors\tfor\tGallstone\tFormation\nModifiable\nNonmodifiable\nHigh-fat\tdiet\nFamilial/genetics\nFemale\tsex\thormone\tuse\nEthnicity\nObesity/metabolic\tsyndrome/diabetes\nFemale\tgender\nRapid\tweight\tloss\nIncreasing\tage\nPhysical\tinactivity\nUnderlying\tdisease:\tcirrhosis,\tCrohn’s\tdise...
[ -0.04068585857748985, -0.059257712215185165, -0.01395359169691801, 0.07908550649881363, -0.07695195078849792, -0.012826116755604744, 0.03919651731848717, 0.05419434607028961, -0.0881376713514328, 0.03273721784353256, 0.03226718306541443, -0.03836735710501671, -0.03977450355887413, 0.023636...
Drugs\nParenteral\tnutrition\nAdapted\tfrom\tStinton\tLM,\tMyers\tRP,\tShaffer\tEA:\tEpidemiology\tof\tGallstones,\n\t\nGastroenterol\tClin\tNorth\tAm\n\t39:157–169,\t2010;\tShaffer\tEA:\tGallstone\tdisease:\tepidemiology\nof\tgallbladder\tstone\tdisease,\t\nBest\tPract\tRes\tClin\tGastroenterol\n\t20(6):981–996,\t2006...
[ -0.016111573204398155, -0.07153788954019547, 0.008262458257377148, -0.01737191528081894, -0.11544982343912125, -0.017339875921607018, 0.02444540150463581, 0.09347350895404816, -0.050417765974998474, -0.030363352969288826, 0.03864164277911186, -0.02638196013867855, -0.0067162178456783295, 0...
Best\tPract\tRes\tClin\tGastroenterol\n\t20(6):981–996,\t2006.\nRisk\tfactors\tfor\tcholesterol\tstone\tformation\tinclude\tfemale\tgender,\tpregnancy,\tolder\tage,\tfamily\thistory,\tobesity\tand\ntruncal\tbody\tfat\tdistribution,\tdiabetes\tmellitus,\tinflammatory\tbowel\tdisease,\tand\tdrugs\t(lipid-lowering\n\tmedi...
[ -0.06975789368152618, -0.042920731008052826, 0.0018300687661394477, 0.006756388116627932, -0.08310260623693466, -0.01782882958650589, 0.011897164396941662, 0.12361760437488556, -0.005650457460433245, -0.03868336230516434, 0.03540166839957237, 0.030301101505756378, -0.04265034943819046, -0....
medications,\noral\tcontraceptives,\tand\testrogens).\tCertain\tethnic\tgroups\tare\tat\tgreater\trisk\tof\tstone\tformation,\tincluding\tNative\nAmericans,\tScandinavians,\tand\tMexican\tAmericans.\tIn\taddition,\tapproximately\t30%\tof\tindividuals\twith\tcirrhosis\thave\ngallstones\t(\nAcalovschi,\t2014\n).
[ -0.03189513459801674, -0.022547369822859764, -0.009345339611172676, -0.007371135521680117, -0.0936981663107872, -0.026643600314855576, 0.052381228655576706, 0.04657045379281044, 0.00515896687284112, 0.08348719030618668, 0.05107688531279564, -0.0530964620411396, -0.017383109778165817, 0.050...
gallstones\t(\nAcalovschi,\t2014\n).\nPigmented\tstones\ttypically\tconsist\tof\tbilirubin\tpolymers\tor\tcalcium\tsalts.\tThey\tare\tassociated\twith\tchronic\nhemolysis.\tRisk\n\tfactors\tassociated\twith\tthese\tstones\tinclude\tolder\tage,\tsickle\tcell\tanemia,\tthalassemia,\tbiliary\ttract\ninfection,\tcirrhosis,...
[ 0.00372020760551095, -0.056007590144872665, 0.028964834287762642, 0.010448791086673737, -0.13861744105815887, -0.03423922508955002, 0.048566970974206924, 0.04670098051428795, -0.04145714268088341, 0.012836526148021221, 0.0663779228925705, -0.005155857652425766, -0.010757059790194035, -0.00...
Medical\tand\tsurgical\tmanagement\nCholecystectomy\n\tis\tsurgical\tremoval\tof\tthe\tgallbladder,\tespecially\tif\tthe\tstones\tare\tnumerous,\tlarge,\tor\tcalcified.\nThe\tcholecystectomy\tmay\tbe\tperformed\tas\ta\ttraditional\topen\tlaparotomy\tor\tas\ta\tless\tinvasive\n\tlaparoscopic\nprocedure.
[ 0.016659528017044067, -0.013505632057785988, 0.060582663863897324, -0.040712956339120865, -0.17358466982841492, -0.07197492569684982, 0.010607616975903511, 0.01597357541322708, -0.00958558265119791, 0.0027651707641780376, 0.045351818203926086, 0.04855428636074066, -0.008272764272987843, 0....
laparoscopic\nprocedure.\nChemical\tdissolution\twith\tthe\tadministration\tof\tbile\tsalts,\tchenodeoxycholic\tacid,\tand\tursodeoxycholic\tacid\n(litholytic\ttherapy),\tor\tdissolution\tby\textracorporeal\tshockwave\tlithotripsy,\tmay\talso\tbe\tused\tless\toften\tthan\tsurgical
[ -0.004232017323374748, -0.0821174755692482, 0.05255890637636185, -0.012323704548180103, -0.12059538066387177, -0.03165028244256973, 0.022929375991225243, -0.017593832686543465, 0.0064844093285501, 0.00603252649307251, 0.08593087643384933, 0.017474032938480377, -0.03416626155376434, 0.03203...
techniques.\tPatients\twith\tgallstones\tthat\thave\tmigrated\tinto\tthe\tbile\tducts\tmay\tbe\tcandidates\tfor\ta\tdiagnostic\nprocedure\tusing\tX-ray\tcalled\tendoscopic\n\tretrograde\tcholangiopancreatography.
[ 0.03094484470784664, -0.005560638848692179, 0.02643251046538353, -0.03685975447297096, -0.20178866386413574, -0.05259121209383011, -0.013301720842719078, 0.08977843821048737, -0.06793472170829773, -0.023893697187304497, 0.025748414918780327, 0.02986256778240204, -0.039378147572278976, 0.06...
Medical\tnutrition\ttherapy\nThe\trole\tof\tdiet\tin\tthe\tpathogenesis\tof\tgallstones\tand\ttherefore\ttreatment\trecommendations\tremains\tunclear.\tObesity\nis\ta\trisk\tfactor,\tbut\tthe\texact\tcomposition\tof\tthe\tdiet\tthat\tresults\tin\tgallstones\tis\tless\tclear.\tDiets\thigh\tin\tcholesterol
[ 0.0027791145257651806, -0.04706277325749397, 0.0441790334880352, -0.003931324928998947, -0.15460197627544403, -0.040581509470939636, 0.06603245437145233, 0.06248246878385544, -0.04800679534673691, 0.024018868803977966, 0.055653005838394165, -0.020441871136426926, -0.012533311732113361, 0.0...
and\tfat\tseem\tto\tincrease\tthe\trisk\tof\tcholelithiasis.\tIn\tcontrast,\tunsaturated\tfats,\tcoffee,\n\tfiber,\tascorbic\tacid\t(vitamin\nC),\tcalcium,\tand\tmoderate\tconsumption\tof\talcohol\treduce\tthe\trisk\t(\nShaffer,\t2006\n).\nThere\talso\tmay\tbe\tsome\tbenefit\tin\treplacing\tsimple\tsugars\tand\trefined...
[ -0.015238557010889053, -0.10069646686315536, 0.046827126294374466, -0.01838614232838154, -0.11401134729385376, -0.008574488572776318, 0.07081521302461624, 0.025223299860954285, -0.02524847351014614, 0.041962046176195145, 0.08014530688524246, -0.049700699746608734, -0.010407419875264168, 0....
Individuals\tconsuming\trefined\tcarbohydrates\thave\ta\t60%\tgreater\trisk\tfor\tdeveloping\tgallstones,\tcompared\twith\tthose\nwho\tconsumed\tthe\tmost\tfiber,\tin\tparticular\tinsoluble\tfiber\t(\nMendez-Sanchez\tet\tal,\t2007\n).\tThus\tplant-based\tdiets\tmay
[ -0.00014179882418829948, -0.009805407375097275, 0.03047884628176689, 0.005692379083484411, -0.11670777201652527, 0.007019012235105038, 0.07066567987203598, 0.017603598535060883, -0.03918095678091049, 0.06057530269026756, 0.11501550674438477, -0.11542848497629166, -0.034396298229694366, 0.0...
Mendez-Sanchez\tet\tal,\t2007\n).\tThus\tplant-based\tdiets\tmay\nreduce\tthe\trisk\tof\tcholelithiasis.\tVegetarian\tdiets\tare\thigh\tin\tfiber\tand\tlow\tin\tfat,\tconsisting\tprimarily\tof\tunsaturated\nfat.\tVitamin\tC,\twhich\tis\tgenerally\thigh\tin\tvegetarian\tdiets,\taffects\tthe\trate-limiting\tstep\tin\tthe...
[ -0.011312760412693024, -0.0049050236120820045, 0.03087969869375229, -0.008785892277956009, -0.06953147798776627, 0.04651189222931862, 0.08516741544008255, 0.0341346338391304, -0.0036852285265922546, 0.06123402714729309, 0.07526086270809174, -0.08696987479925156, 0.049620773643255234, 0.075...
cholesterol\tto\tbile\tacids\tand\tinversely\tis\trelated\tto\tthe\trisk\tof\tgallstones,\tespecially\tin\twomen.\nWeight\tcycling\t(repeatedly\tlosing\n\tand\tregaining\tweight),\tfasting,\tand\tvery-low-calorie\tdiets\tincrease\tthe\tlikelihood\nof\tcholelithiasis.\tAlong\twith\tweight\treduction,\tsome\tevidence\tin...
[ -0.011237849481403828, -0.0769234225153923, 0.05085839331150055, 0.027490798383951187, -0.13153141736984253, -0.05374113470315933, 0.07567299157381058, 0.01250424887984991, -0.019366707652807236, 0.024784225970506668, 0.11756448447704315, -0.07398074865341187, -0.00345517392270267, -0.0128...
cholecystitis.\tIn\tcholecystitis,\tMNT\tincludes\ta\thigh-fiber,\tlow-fat,\tplant-based\tdiet\tto\tprevent\tgallbladder\ncontractions.\tData\tare\tconflicting\tas\tto\twhether\tintravenous\tlipids\tstimulate\tgallbladder\tcontraction.\nAfter\tsurgical\tremoval\tof\tthe\tgallbladder,\toral\tfeedings\tcan\tbe\tadvanced\...
[ 0.025954902172088623, -0.12411277741193771, 0.06590893864631653, 0.0029299897141754627, -0.16068117320537567, -0.09428209811449051, 0.023706650361418724, 0.014764947816729546, -0.023772498592734337, -0.014974747784435749, 0.0650731697678566, 0.021716168150305748, 0.01691138930618763, 0.032...
lower\tfat\tdiet\twith\tadequate\tsoluble\tfiber\tmay\tbe\timportant\tat\tfirst.\tIn\tthe\tabsence\tof\tthe\tgallbladder,\tbile\tis\tsecreted\ndirectly\tby\tthe\tliver\tinto\tthe\tintestine.\tThe\tbiliary\ttract\tdilates,\tforming\ta\t“simulated\tpouch”\tover\ttime\tto\tallow\tbile\tto\nbe\theld\tin\ta\tmanner\tsimilar...
[ 0.037908997386693954, -0.0758935883641243, 0.08389909565448761, -0.05540024861693382, -0.1816047579050064, -0.04193373769521713, 0.03699290752410889, 0.036805570125579834, 0.003567067440599203, 0.040483806282281876, 0.08905252814292908, -0.007430993486195803, 0.04199706390500069, 0.0300153...
be\theld\tin\ta\tmanner\tsimilar\tto\tthe\n\toriginal\tgallbladder.\tSome\tpatients\tmay\tdevelop\tfrequent\tloose,\twatery\tstools\tif\nthey\teat\tfatty\tmeals\tduring\tthis\tadaptation\ttime\tframe.\tIn\tmost\tcases,\tthe\tdiarrhea\tis\ttemporary\tand\tself-limiting.\nCholecystitis\nPathophysiology\nInflammation\tof\...
[ 0.038401175290346146, -0.1135435551404953, 0.047827012836933136, -0.009754923172295094, -0.1644044816493988, -0.07669613510370255, 0.0321626253426075, 0.04172956570982933, -0.014356628991663456, -0.007380613591521978, 0.06038397178053856, 0.03821795433759689, 0.016399480402469635, 0.057278...
Inflammation\tof\tthe\tgallbladder\tis\tknown\tas\t\ncholecystitis\n,\tand\tit\tmay\tbe\tchronic\tor\tacute.\tIt\tusually\tis\tcaused\tby\ngallstones\tobstructing\tthe\tbile\tducts\t(calculous\n\tcholecystitis),\tleading\tto\tthe\tbackup\tof\tbile.\tBilirubin,\tthe\tmain\tbile
[ 0.016558850184082985, -0.10839620977640152, 0.022845648229122162, -0.0017862673848867416, -0.10877341032028198, -0.037254344671964645, 0.03532542288303375, 0.05685550719499588, 0.0009873900562524796, 0.03346354141831398, 0.042216721922159195, 0.027355274185538292, 0.04126539081335068, 0.07...
pigment,\tgives\tbile\tits\tgreenish\tcolor.\tWhen\tbiliary\ttract\tobstruction\tprevents\tbile\tfrom\treaching\tthe\tintestine,\tit\nbacks\tup\tand\treturns\tto\tthe\tcirculation.\tBilirubin\thas\tan\taffinity\tfor\telastic\ttissues\t(such\tas\tthe\teye\tand\tthe\tskin);\ntherefore\twhen\tit\toverflows\tinto\tthe\tgen...
[ 0.0009552356204949319, -0.03805060312151909, 0.07457520812749863, -0.035016585141420364, -0.08861593902111053, -0.0008611471857875586, 0.12641781568527222, -0.008333997800946236, 0.00389417284168303, 0.06116029620170593, 0.05825197324156761, -0.07084996998310089, 0.01730787567794323, 0.030...
and\teye\tdiscoloration\ntypical\tof\t\njaundice\n.\nAcute\tcholecystitis\twithout\tstones\t(acalculous\tcholecystitis)\tmay\toccur\tin\tcritically\till\tpatients\tor\twhen\tthe\ngallbladder\tand\tits\tbile\tare\tstagnant.\tImpaired\tgallbladder\temptying\tin\tchronic\tacalculous\tcholecystitis\tappears\tto\tbe
[ 0.04967137798666954, -0.06806191056966782, 0.04219895228743553, 0.010922187007963657, -0.15682850778102875, -0.059752192348241806, 0.08232297748327255, -0.003804718144237995, 0.018010837957262993, -0.005452403798699379, 0.076931893825531, 0.005464365240186453, 0.04467179998755455, 0.038956...
due\tto\tdiminished\tspontaneous\tcontractile\tactivity\tand\tdecreased\tcontractile\tresponsiveness\tto\tCCK.\tThe\twalls\tof\tthe\ngallbladder\n\tbecome\tinflamed\tand\tdistended,\tand\tinfection\tcan\toccur.\tDuring\tsuch\tepisodes,\tthe\tpatient\texperiences\nupper-quadrant\tabdominal\tpain\taccompanied\tby\tnausea...
[ 0.009262307547032833, -0.028055693954229355, 0.0774124413728714, -0.03962317109107971, -0.09419986605644226, -0.06198051944375038, 0.08364661782979965, 0.011860026977956295, -0.0012629906414076686, 0.039950136095285416, 0.06642170250415802, -0.07443471997976303, 0.024915684014558792, 0.055...