Datasets:
OTAR3088
/
BioData-CellLine_annotated

Dataset card Data Studio Files
xet
 Community
1
PMCID
string
Sentences
string
ner
list
PMC11046454
To indicate the expression of anti-FITC CAR, enhanced green fluorescent protein (EGFP) was noncovalently linked at the C-terminus with a Thosea asigna virus (T2A) ribosomal skip element, which could rule out any possible interference of EGFP on the CAR function.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11551844
Contignasterol and AuNPs-contignasterol displayed IC50 values of 7.42 ± 0.64 μM and 7.10 ± 2.20 μM, respectively.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Contignasterol", "and", "AuNPs-contignasterol", ...
PMC11279397
Aldehydes constitute a class of organic compounds with significant activity, naturally present in various food sources and ingredients, rendering them highly intriguing in both academic and industrial contexts.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10809689
Also, evaluating the relationship of these pathways in peripheral blood or bone marrow samples taken from AML patients and measuring the protein expression of GDH enzyme with western blot technique are other suggestions of this research for future studies.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
However, 5 to 20% are primary refractory to treatment or relapse after achieving a complete remission (CR) and present a therapeutic challenge.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC8633974
Progeny virion production was measured by reverse transcriptase (RT) activity in culture fluids. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Progeny", "virion", "production", "was", "measured", "...
PMC10713411
B, C) Kaplan–Meier survival and ROC curves based on PRPCDGs risk signature. (
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "B", ",", "C", ")", "Kaplan", "–", "Me...
PMC9429973
All clinical and laboratory results were identified at initial visit and at follow-up timepoint.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "All", "clinical", "and", "laboratory", "results", "were", "identified"...
PMC11541241
In this review, we delve into a comprehensive analysis of the intricate signalling landscape of the TOR network in phytopathogens, highlighting the specific inhibitors commonly employed to target this pathway.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC3888431
The application of CHO cells in the large-scale production of pharmaceutical proteins generates revenues of billions of dollars each year with numbers constantly rising .
[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "token...
PMC11599565
All studies were carried out and reported according to the German Animal Welfare Act and ARRIVE (Animal Research: Reporting of In Vivo Experiments) recommendations and guidelines.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10652261
In an attempt to identify small molecules for the treatment of leukemia, 12 new pyrazolines (2a–l) were synthesized efficiently.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11672617
Cytochrome c is a soluble protein that is localized in the intermembrane space of mitochondria.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cytochrome", "c", "is", "a", "soluble", "protein", "that", ...
PMC11721096
Active compounds in C. arabica, such as gamma-tocopherol, may help prevent skin pigmentation .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Active", "compounds", "in", "C.", "arabica", ",", "such", ...
PMC7917457
By the time all mock-treated mice had died or been sacrificed due to the tumors reaching the maximum volume allowed in the PeptiCRAd VALO-mD901-Trp2-treated group and anti-PD-1-treated group, 3/9 (33.3%) and 5/8 (62.5%) mice were still alive, respectively.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11757230
Given this, the purpose of our study was to evaluate the safety of MSC-based therapy for CIE, focusing on its potential pro-tumorigenic characteristics.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9592219
Similarly, the recombinant TOP2A plasmid induced the production of SK-HEP-1 cells with stronger migration ability (Figure 4(d)).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Similarly", ",...
PMC11790599
However, TSL-induced macropinosomes, as visualized by FITC-dextran (70 kDa), did not extensively overlap with lysosomes stained with LysoTracker Red in SK-BR-3 and ZR-75-1 cells (Figure 3H).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", ...
PMC11684297
At a higher magnification with a 5 nm scale bar, the distinct crystalline lattice planes of the sheets become clearly visible.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "At", "a", ...
PMC9681981
This pathogen produces several protein toxins including the potent ε-toxin which is classified as a category B toxin by the Centers for Disease Control and Prevention (CDC).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8903741
It should be noted that, contrary to the commercial anti-hMMP9 antibody from hybridoma cells, the antibody developed in this study was produced from CHO cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", ...
PMC9964635
Akt plays a vital role in internal cell signalling by accelerating cellular survival and proliferation.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Akt", "plays", "a", "vital", "role", "in", "internal", ...
PMC10213179
injection of aptamers, ATOP or SCR, 20 nmol/mice (1.6 mg/kg) after cell inoculation every 3 days from day 1 until day 22.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11310713
The GTB treatment restored 98.76% of Tb.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "GTB", "treatment", "restored", "98.76", "%", "of", "Tb", "." ] } ]
PMC11098378
Together, our findings demonstrate the utility of using naturally abortive arbovirus infections in lepidopteran cells for the interrogation of arbovirus-host interactions and establish it as a model for identifying conserved host immunity proteins targeted by pathogens.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11731614
CryoEM images are obtained through the northwestern BioCryo core facility (NUANCE) with samples prepared as previously described (Asadi, 2017).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11627133
Characterization of AP3‐SiRA and its application in dual‐color protein imaging.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Characterization", "of", "AP3‐SiRA", "and", "its", "application", "in", "dual‐color", "protein", ...
PMC10380508
In agreement with the TCGA data analysis, PAX2 showed relatively high expression levels in most RCC cell lines, with PAX2 and PAX8 exhibiting higher expression than PAX6.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11750161
Finally, for the rec-eCG protein assay, the supernatant was collected on day nine post-transfection.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Finally", ",", "for", "the", "rec-eCG", "protein", ...
PMC10907726
These results highlight the potential of DATS as an important therapeutic agent for the treatment of OS.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "results", "highlight", "the", "potential...
PMC9429973
Achieving of HI-P during first two cycles was associated with better overall survival (p=0.0341).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Achieving", "of", "HI-P", "during", "first", "two", ...
PMC9429973
18 bacterial infections, the most was Klebsiella pneumoniae (n=5).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "18", "bacterial", "infections", ",", "the", "most", "was", "Klebsiella", "pneumo...
PMC9841531
Therefore, compounds 24 and 30 were dually effective against MCT1- and ABCB1-expressing cells (Table 5).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therefore", ",", "compounds", "24", "a...
PMC11545737
In fact, the meningococcus can breach the mucosal barrier, reaching the bloodstream and causing meningococcemia.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "fact", ",", "the", "meningococcus", "...
PMC11740508
Data analysis used FlowJo (BD Biosciences).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "analysis", "used", "FlowJo", "(", "BD", "Biosciences", ")", "." ] } ]
PMC11537649
Due to the clinical and functional relevance of Lnc RNAs in tumor progression, research on Lnc RNAs is receiving extensive attention.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Due", "to", ...
PMC11536589
Kirsten rat sarcoma viral oncogene homolog (KRAS) is a frequently mutated gene in various types of solid tumors, such as colorectal cancer, lung adenocarcinoma, and PDAC (Li et al. 2018).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10073922
A549 and LX-2 cell lines were cultured at 1×10 and 1.5×10 counts in six-well plates, respectively.
[ { "tags": [ "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A549", ...
PMC11562028
Moreover, the downregulation of the PI3K/AKT signaling pathway would upregulate the expression level of the downstream p21 protein and inhibit the formation of the CDK2–CCNA2 complex, which would lead to cell cycle arrest in the S phase along with the inhibition of cell proliferation.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11566417
Antimicrobial assays were conducted with minor modifications from previously published protocols .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Antimicrobial", "assays", "were", "conducted", "with", "minor", "modifications", "from", "p...
PMC11525028
To illustrate the role of NAT10 in osteosarcoma growth and metastasis in vivo, we built tibial orthotopic xenograft osteosarcoma models in BALB/c nude mice and observed the tumor volume and lung metastasis.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", ...
PMC7887261
In contrast, both p.I157T and p.S428F showed an increased risk of breast cancer.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "contrast", ",", "both", "p.", "I157",...
PMC11770199
At the endpoint, mice were euthanized and the tumors were harvested.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "At", "the", "endpoint", ",", "mice", "were", "euthanized", "and", "the", "...
PMC9429973
The expression level of RRAD is closely related to the presence or absence of bone disease, which affects the patient’s quality of life and prognosis assessment.3.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11224020
e, Left, representative images of DCs showing CCR7 expression (gray) and nuclei (red).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "e", ",", "Left", ",", "repr...
PMC9429973
A single centre study of MF (Masarova et al, Blood Advances, 2017) found no survival difference between patients exposed to chemotherapy/radiation and those managed with surgery/observation/hormone therapy.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11434983
Notably, both complexes significantly enhanced radiosensitivity in A431 cells, suggesting their potential in combined modality treatments.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Notably", ",", "both", "complexes", "s...
PMC11765678
In addition, RSL3 was also effective in sensitizing WT cells to ADR and TPT (Figure 2D,E).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "addition", ...
PMC11769516
The established tolerance is based on estrogenicity in pigs.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "established", "tolerance", "is", "based", "on", "estrogenicity", "in", "pigs", "." ] } ]
PMC11585994
Before TEM imaging, the samples were stained in uranyl acetate (Electron Microscopy Sciences, 22400) for 1 minute.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Before", "TEM", "...
PMC11726848
In the case of intracellular signaling, they participate in the pathways of cyclin-dependent kinases (CDKs).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", "the", "case", "of", "intracellul...
PMC11721295
Data were scaled and centered using linear regression of transcript counts.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Data", "were", "scaled", "and", "centered", "using", "linear", "regression", "of", "t...
PMC11342785
We stimulated cells with blue light for 5 min to assemble TPPP clusters and then monitored cluster disassembly over time in in the dark (Figs. 3D and S4).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
This is further emphasized by the coherent deregulation of BCL-xL and BAK throughout carfilzomib exposed carfilzomib resistant cell lines when compared to their sensitive cell line variants.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11632064
While MITF has been shown to antagonize pro-inflammatory responses through inhibition of NF-κB and AP-1 in melanoma (Riesenberg et al, 2015), we did not observe a reduction in MITF and PGC-1α transcript in MeWo cells treated with the RSK/PLK1 inhibitor BI-D1870.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11767725
Nonetheless, as more data become available and ML models grow more accurate, their capacity to unravel the complex interplay between metabolic disorders, the microbiota, and skin health will only expand, enabling transformative advances in personalized medicine.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11770199
Syncytia were shrunk and died at the late stage of cell fusion.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Syncytia", "were", "shrunk", "and", "died", "at", "the", "late", "stage", ...
PMC7351993
Therefore, sorted cells are collected from the outlet regardless of the direction of the local flow.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Therefore", ",", "sorted", "cells", "are", ...
PMC9341513
The model combines three mechanisms which drive locus structure: (1) diffusing spheres representing complexes of chromatin binding proteins which can bind to multiple points at the same time to form molecular bridges (e.g., between promoters and enhancers) (Brackley et al. 2013, 2016b; Brackley 2020); (2) a heteromorphic polymer structure, where different sections of the bead chain have different properties (thickness/compaction and flexibility); and (3) the loop extrusion mechanism (Sanborn et al. 2015; Fudenberg et al. 2016).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11727145
Researchers initially utilized materials such as postmortem pig skin, as reported by Freemann et al. in 1976, and later with human cadaver skin by Wainwright in 1995 or Boelsma in 1999 .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11172027
After 48 h of incubation on Jurkat cells, there was already a clear reduction in activity to 78.0 ± 6.2% (n = 3) compared to the control (100 +/− 11.0%; n = 3; p < 0.05), and at 200 µg/mL (56.9 ± 5.9%, n = 3), there was a further significant reduction compared to the control (p = 0.03).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11643361
The U1285 and cisplatin-resistant C13 cell lines were particularly susceptible, with the silver complexes showing up to 14-fold greater potency than cisplatin in some cases.
[ { "tags": [ "O", "B-CellLine", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC11697703
Briefly, viable FACS-sorted cells, 50,000 per biological replicate, were lysed in non-ionic detergent to isolate the nuclei.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Briefly", ",", "viable", ...
PMC9429973
Methods: Patients who underwent leukapheresis for standard-of-care brexu-cel manufacture at one of the 16 Consortium centers between 8/1/2020 and 12/31/2021 were included.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Methods...
PMC9429973
Nausea, vomiting, and diarrhea decreased as Tx continued.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Nausea", ",", "vomiting", ",", "and", "diarrhea", "decreased", "as", "Tx", "continued", "....
PMC11322866
In this senescence model, Lamin B1, a key component of the nuclear envelope and a marker of senescence, does not decrease but instead undergoes aberrant accumulation.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11746948
Cells grown on sterile coverslips in a 6-well plate were washed once with 1× PBS, fixed with 4% PFA for 20 min, and then permeabilized with 0.2% Triton X-100 for 20 min.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11064533
The reintroduction of the flgH gene in ΔflgH, i.e., ΔflgH + pBAD33 flgH resulted in significant (P = 0.05) regeneration of clumpy adhesion up to 70%, confirming the role of flagella in adhesion.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11045125
The relatively high level of Myc expression (induced by EBNA2) that occurs early after EBV infection in normal B cells has been shown to reduce (but not eliminate) LMP1 levels, although the mechanism for this effect is unclear .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11365427
NCI-H929 cells were attached to polylysine-coated cell slides overnight at 37 °C and 5% CO2.
[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "NCI-H929", "cells", "were", "attached", ...
PMC11442172
3D cell culture platforms, including tumor spheroids and organoids, replicate many of the pathophysiological features of solid tumors, such as cell-cell contacts as well as pH, oxygen and nutrient gradients (15).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11470999
We then hypothesized that PF might affect CIP2A protein stability.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "then", "hypothesized", "that", "PF", "might", "affect", "CIP2A", "protein", "stability", ...
PMC11089031
The “LinkFinder” and “LinkInterpreter” modules of the LinkedOmics online tool were used to identify genes whose expression was positively or negatively correlated with ZNF692 expression and were then used to perform GO biological process analysis.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973
Aims: The present study is a 3-years follow-up update of a previously published Italian real-life RRMM cohort of patients treated with EloRd.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Aims", ...
PMC10218459
In the current study, this explains the CPP effect of direct treatment, with the immediate death of some cells seen at the cell count determination after 4 h. The induction of apoptosis is one of the key mechanisms associated with the anti-tumoral effect of CPP on cancer cells .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11300639
Clear cell renal cell carcinoma (ccRCC) is the main histological type of renal cell carcinoma (RCC), accounting for approximately 75% of all RCC cases, and is one of the main types leading to RCC-related death .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11468365
Deep learning models play a significant role in biomedical applications, including predicting drug combinations, drug-drug interactions , drug toxicity , drug-target interactions , and so on.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9812014
These findings point to manzamines as a promising lead for reducing viral infection in corneal cells and preventing eye infections including keratitis induced by HSV-I .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC7229095
CDM3 also suffered from the poor recovery of clones grown in 96-well plates, and few could be successfully scaled up for culturing in 6-well plates.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC9429973
A. Le Floch, K. Nagashima, T. Norton, L. Perlee, A. Murphy, M. Sleeman, J. Orengo Inflammation and Immune Diseases; Regeneron, Tarrytown, United States of America Background: Pathogenic T-cell responses in T cell-mediated diseases can be driven by cytokines of the common gamma chain (γc) cytokine family (IL2, IL4, IL7, IL9, IL15, and IL21).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11796104
During the aging process, bone marrow mesenchymal stem cells (BMSCs) exhibit declined osteogenesis accompanied by excess adipogenesis, which will lead to osteoporosis .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11721064
Herein, we established a two-step transdifferentiation protocol for KPCs.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Herein", ",", "we", "established", "a", "two-step", "transdifferentiation", "protocol", "for", "...
PMC11672881
Additionally, downregulated genes like ZP4, TGM2, and MMP9 are primarily involved in the cellular structure and migration .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Additionally", ",", "downreg...
PMC11805741
MDA-MB-231 cells cultured in 96 well plates were treated with serial concentrations of paracoccus sp. EGY7 carotenoids extract (0, 37.5, 75, 150, 300, 600, 1200 µg) dissolved in 0.01% DMSO.
[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11222184
In this study, we aimed to investigate the comprehensive molecular pathways of the anticancer activity of XL-888 and Debio0932 in human neuroblastoma cells SH-SY5Y.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O" ],...
PMC7812570
TZM-bl cells expressing GPI-m36.4 or GPI-FluIgG03 were used as targets and cocultured with CEMss-CCR5 donor cells that were preinfected with one of the three viruses. %
[ { "tags": [ "B-CellLine", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11680982
Cyclin D1, CDK4 and EGFR protein expression levels in HR/HER2-low breast cancer, measured by western blot. *
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cyclin", "D1", ",", "CDK4", ...
PMC11612794
The cells were cytospan onto slide glasses or coverslips by the Cytospin3 centrifuge (Shandon).
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "cells", "were", "cytospan", "onto", "slide", ...
PMC10850553
Therefore, tPA may trigger C5a-related events, such as neutrophil recruitment and inflammatory responses, by converting Plasminogen into Plasmin and drive the pathogenesis leading to rupture of IAs.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10197932
The Ultrasound (US) has a great potential for therapeutic applications, specifically for induction of apoptosis in cancer cells, and drug delivery 1-4.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11469524
Systematic perturbation data shown as log2 fold changes to solvent control DMSO.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Systematic", "perturbation", "data", "shown", "as", "log2", "fold", "changes", "...
PMC9096373
RT, particularly concurrent RT based on cisplatin (DDPs), is a standard treatment for locally advanced cervical cancer.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "RT", ",", "partic...
PMC11473843
The migration assay was performed using a Transwell system (8-µm pore size Pore Polycarbonate Membrane Insert; Catalog.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "migration", "assay", "was"...
PMC11566417
The trypsin reaction was inactivated with EpSC medium, and cells were pelleted at 300 × g for 5 min at RT.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "tryps...
PMC11730311
Results are presented as mean ± range of n = 3.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Results", "are", "presented", "as", "mean", "±", "range", "of", "n", "=", "3", ...
PMC11629143
This is consistent with p300 and/or CBP contributing selectively to H3K27 acetylation in CHO‐K1 cells, as in other cell types.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "is", ...
PMC8973725
For example, ZNF471 is significantly hypermethylated and has low mRNA expression in esophageal cancer compared with that in normal tissues .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "example", ...
PMC11720808
When the tumor volume reached about 60 mm, the mice were randomly assigned to one of four groups: (1) the TLR4 OE group, subcutaneously injected with stably overexpressing TLR4 143B cells; (2) the TLR4 OE + SCU group, subcutaneously injected with stably overexpressing TLR4 143B cells and treated with SCU; (3) the control group, subcutaneously injected with wild-type 143B cells; (4) the SCU group, subcutaneously injected with wild-type 143B cells and treated with SCU.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11650848
Imprinted genes are a case of parent-of-origin expression escaping epigenetic reprogramming through maintenance of DNA methylation on one or more imprinting control regions (ICR) .
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC10998613
Summary of single-cell cross-correlation values (fc) for CXCR4 and β2AR heteromultimerization with (+) or without (−) ligand stimulation in the membranes of MDA-MB-231 cells.
[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...