OTAR3088/BioData-CellLine_annotated · Datasets at Hugging Face

PMCID string	Sentences string	ner list
PMC11656657	For the stimulation assays with 1A7 anti-idiotypic antibody, non-transduced (NT) T-cells and CAR.GD2 T-cells were incubated with 0.5 ng/mL of 1A7 anti-idiotypic antibody for 72 h. The 1A7 antibody was used to mimic stimulation by the tumor-associated antigen disialoganglioside GD2.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10958426	GO enrichment analysis of DEGs with high CNV-expression correlation (DEGCNV) and DEGs with low CNV-expression correlation (DEGreg).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "GO", "enrichment", ...
PMC11012012	Later, Yigit et al. (2016) reported that upon transplantation of an aggressive murine B220+ CD5+ CLL cell clone, TCL1-192, into SCID mice, one injection of an anti-SLAMF6/CD352 monoclonal antibody abrogated tumor progression in the spleen, bone marrow, and blood, but not in the peritoneal cavity or omentum .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11674441	Indeed, the IFN-γ ELISpot data for BC5 showed that when HLA class II-restricted neoantigen peptide-pulsed DCs and CD4-positive T cells and CD8-positive T cells obtained after Neo-P DCs vaccination were co-cultured, the degree of lymphocyte activation increased even further than the sum of activation levels when they were co-cultured separately.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10547921	Continuous DNA damage is caused by cross-linking between DNA chains, which leads to cell cycle arrest in the G2/M phase and cell apoptosis, thus exhibiting a powerful cytotoxic effect.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10024132	Briefly, tumor cells were first stained with PKH26 (Sigma) and 5(6)-carboxyfluorescein diacetate succinimidyl ester (CFSE; Invitrogen).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Briefly", ",...
PMC11740207	Comparative molecular profiling of VSELSCs or VSLSLCs with existing datasets from early human embryonic stages and somatic cells is essential to elucidate their unique and shared characteristics.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11748618	Each data point (pink) represents a meQTL in the chromosome 1 region in linkage disequilibrium (r = 1) with rsrs72999655-A-G. The vertical bars show whether the meQTL is associated with hypermethylation (red) or hypomethylation (blue).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11697703	FACS purifications were performed by the Stanford Shared FACS Facility.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "FACS", "purifications", "were", "performed", "by", "the", "Stanford", "Shared", "FACS", "Facilit...
PMC11737091	L-N) Diagnostic ROC analysis with the AUC of DBF4 in ccRCC. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "L-N", ")", "Diagnostic", "ROC", "analysis", "with", "the", "AUC", "of...
PMC9429973	The initial diagnosis of ETP-ALL was based on the results of bone marrow cytology and flow cytometry immunophenotype.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "initial", "diagnosis", "of", "E...
PMC6034753	Subsequently, after washing, cells were incubated with Alexa 488 (CEF and DF-1 cells)/ 568 (MSB-1 cells)-conjugated goat anti-rabbit antibodies.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O" ], ...
PMC11721587	The cells were scraped off the plate and washed with cold PBS twice and resuspended with cold Farnham lysis buffer [5 mM Pipes (pH 8.0), 85 mM KCl, 0.5% NP-40, and 1× complete protease inhibitors cocktail].	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11389534	UBL modifications participate in the modulation of immune responses by specifically targeting immune receptors, adaptors, enzymes and transcriptional factors.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "UBL", "modifications", ...
PMC6892818	For detection of intracellular ROS levels, cells were treated with 1 μM H2DCFDA (Thermo Fisher Scientific) for 30 min, fluorescence measurements (relative fluorescence units, RFU) were taken spectrophotometrically and results expressed as fold increase in RFU, as described in detail previously.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9532503	For example, it is well established that the absence of core fucose leads to increased ADCC activity .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "example", ",", "it", "is", ...
PMC6160470	Although the tested compounds did affect Akt signalling pathway, this did not ultimately alter P-gp expression and is probably not the underlying mechanism of action.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC7887261	Sensitive DNA damage assays by flow cytometry were performed as previously described.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Sensitive", "DNA", "damage", "assays", "by", "flow", "cytometry", "were", "perfo...
PMC9429973	We show that spleen function is partially preserved in many adults with SCD.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "show", "that", "spleen", "function", "is", "partially", "preserved", ...
PMC11082662	Cancer has the highest mortality rate among gynecological cancers and poses a serious threat to women’s lives.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cancer", "has", "the", "highest", "mor...
PMC10809689	Significant variation for the PMA group compared to the control group was reported (p = 0.04) (Fig. 9 (a.)).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11298021	Expression of PI3K, AKT, mTOR, and S6KB1 genes in Jurkat cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "Expression", "of", "PI3", "K", ",", "AKT", ",", ...
PMC11665555	In addition, the Markus Riester high-risk cohort BCa dataset (n = 93) revealed that OXCT1 was significantly expressed in invasive disease (pT4) while HMGCS2 was downregulated at higher disease stages, showing a correlation with muscle invasive disease (Figure 1, A and B) (23).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11461874	The precipitate was resuspended in SDS-PAGE sample buffer [10 mM Tris-HCl, 2 mM EDTA, 2% SDS, 6% glycerol, 50 mM DTT, 0.02% CBB R-250; pH 6.8] and incubated at 95 °C for 5 min, used as “nuclear fraction”.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9895440	Then the drugs were added to the cells, mixed rapidly and incubated again.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Then", "the", "drugs", "were", "added", "to", "the", "cells", ...
PMC9429973	Network and Pathway Enrichment Analysis MMP9 (degree=9) and CCNA2 (degree=7) showed significant importance (Fig 2A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Network", "and", ...
PMC11791264	The consensus SETD7 recognition sequence, the lysines targeted for methylation by SETD7 in known substrates, and the methylated lysine are shown in red in each case.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9926039	An in vitro trans well migration assay was performed by uncoated 8 μm pore size membranes (SPL Life Sciences, South Korea).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC8922418	One of the most significant challenges in the treatment of AIDS is eliminating the latent reservoir in HIV-1 infected cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "One", "of", "the", "mo...
PMC6650823	Highlighted by Simona Collina Riboswitches are regulatory, noncoding RNA aptamers that regulate gene expression by binding to specific small molecules.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Highlighted", "by", ...
PMC10671321	Some data suggest that ColQ/MuSK/LRP4 interaction impacts the activity of signalling pathways leading to specific mRNA regulation, the number and the size of AChR clusters, as well as membrane levels of MuSK .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11360263	Evidence from in vitro and in vivo data indicated that HCMV might play a role in the onset or progression of breast cancer .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Evidenc...
PMC11705630	We then assessed the expressions of GLDC and ISGF3 in xenografted tumor tissues and confirmed decreased GLDC and increased IRF9 and STAT2 expressions (Fig. 8D-E).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11216402	The combined differential expression of these TF genes and the identification of their TF binding sites as the largest signals in predictive sequence modeling of the chromatin accessibility profiles strongly suggest that the variability in activation of this small set of TFs is responsible for driving the EMT program.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11394112	We confirmed the genotype by PCR using the following primer sets (IL6, 5′ AGG GAG AGC CAG AAC ACA GA 3′ and 5′ TGC AGC TTA GGT CGT CAT TG 3′; CSF2, 5′ ACC TGC CTA CAG ACC CG 3′ and 5′ AGT GCT GCT TGT AGT GGC 3′; IL3, 5′ AAT CTC CTG CCA TGT CTG C 3′ and 5′ CCA GTC ACC GTC CTT GAT ATG 3′; KITLG, 5′ CAA GGA CTT TGT AGT GGC ATC TG 3′ and 5′ CAA CAG GGG GTA ACA TAA ATG G 3′).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11411131	CGCs were prepared from 7-day-old mouse pups.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CGCs", "were", "prepared", "from", "7-day-old", "mouse", "pups", "." ] } ]
PMC11731161	A–D NCI-H929 and MM.1S cells were transfected with the tet-on-shRNA either with control sequence (NC) or sequences targeting USP7 (#1 and #2), cells were treated with 1ug/ml DOX for 48 h, USP7 (A and B) and XPO1 (A and C) protein levels were analyzed by immunoblotting and were quantitatively analyzed.	[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC9926039	The ΔΔCt value was calculated by obtaining the difference between the ΔCt values of the treated and untreated cells (ΔΔCt = ΔCt (treated cell)-ΔCt (untreated cell).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11075223	For example, Cimicifugae Rhizoma has a good effect on treating vertigo with compatibility of Polygonatum sibiricum Red .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "example", ",", "Cimicifugae", "...
PMC10604092	Data were analyzed statistically using Student’s t-test or Welch’s t-test on the basis of the result of an F test (GraphPad Prism 9 version 9.5.1; GraphPad Software, San Diego, CA, USA).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8633974	Statistical calculations set type I error cut-off α = 0.05 and were performed using GraphPad Prism v7.0a or 9 for Mac OS X (GraphPad Software, San Diego, California USA, www.graphpad.com).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5308810	A representative graph of six independent experiments was performed.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "representative", "graph", "of", "six", "independent", "experiments", "was", "performed", "." ] }...
PMC11594641	Cell invasion was studied using the QCM ECMatrix Cell Invasion Assay (Merck Millipore, Burlington, MA, USA) according to the manufacturer’s protocol.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9454178	As expected, the results showed that THZ1 treatment led to a profound reduction in tumour volume and weight, corroborating the tumour inhibition effect in vitro (Fig. 4A).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11310713	(G), and bone volume/total volume (BV/TV) (H) in GTB or pharmaceutical hormone-treated OVX rats compared to ovary-intact and OVX rats.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9910796	However, the closest relatives of ASFV, the amoeba-infecting faustovirus , pacmanvirus and kaumoebavirus , together with the mollusk-infecting abalone asfa-like virus (AbALV) , encode homologs of polyproteins pp220 and pp62 as well as ASFV protease.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8633974	A gRNA library was screened against a panel of HIV-1 molecular clones by co-transfection into HEK293FT cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "A", "gRNA", "library", "was", "screened"...
PMC9164404	E Fluorescence distribution of Abplatin@Cy5.5 at 12 h in different focal planes of 3D tumor sphere, scale bar = 100 µm.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "E", "Fluores...
PMC11783017	Next, 5 mg of the previously synthesized Cis/Mn@Lipo-IL11 (quantified by cisplatin) and 5 mg of NHWD-870 were added to 250 mg of PGP (3 %/1.5 %).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10213199	These results provide enlightenment to further improve our understanding of the specific active ingredients in traditional Chinese medicines.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "results", "provide", "enlightenment...
PMC11394227	The expressions of PERK, BiP, and CHOP protein in CHO-PAb cells increased by 1.29 times, 1.56 times, and 1.32 times, respectively, while those in CHO-PAb-QS cells increased by 1.15 times, 1.06 times, and 1.43 times, respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10507284	Hence, we can roughly infer that the downregulation of TROAP could significantly attenuate the proliferation, migration, and invasion ability of STS cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11718109	Quantification of vesicle diameter was performed using randomly sampled images from clustered vesicles in classical synapses and bouton-like structures for DA neurons, and large droplets in COS7 cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", ...
PMC11568601	After rinsing three times with PBS, secondary antibodies were added, and the mixture was incubated for 1 h. Finally, DAB staining solution (Beyotime Biotech.,	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9792775	Growth curves generated with OD450 data with the CCK8 assay for A-204 cells treated with LFU and PTX. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Growth", "curves", "generated"...
PMC11738017	The dotted black line represents the starting cell viability without the addition of TCE.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "dotted", "black", "line", "represents", "the", "starting", ...
PMC10988555	These results demonstrate that complexes may be internalized by an active transport, as reported by other authors, but they are also able to enter cells by passive diffusion.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9817179	A low 405 nm activation power was used to ensure sufficiently sparse activation of PA-JF646-labeled proteins and allow for SPT.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "low", "405", "nm"...
PMC11095939	Protein concentrations were quantified using a BCA Protein Assay Kit.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Protein", "concentrations", "were", "quantified", "using", "a", "BCA", "Protein", "Assay", "Kit"...
PMC11279397	This enabled us to integrate these virus-associated target genes with the Perilla-related target genes for subsequent analysis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "enabled", "us", "to", "integrate", ...
PMC9268183	The field of ethnobotany focuses on documenting traditional knowledge and uses associated with plants, providing baseline information for plant screenings to be used during the treatment and/or prevention of certain diseases .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11155445	Compounds (101a–c) also showed prominent activity against HepG2 having cell viability of 35.01%, 37.31%, and 39.22%, respectively, while compounds (101e and 101f) were found least active against all tested cancer cell lines having high cell viability (63.75–82.81%) (Fig. 37).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9454852	cDNA then was obtained utilizing the Transcriptor First Strand cDNA Synthesis Kit (Roche Diagnostics GmbH, Penzberg, Germany).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "cDNA", "then", "w...
PMC9587866	This was achieved through GalaxyRefine database, which further improved the structural and topical features of EYA3 protein model.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "was", "achieved", "throug...
PMC9429973	The primary objective is to determine the safety and tolerability (phase 1) and overall response rate (ORR, defined as CR+mCR) (phase 2) of Ven+ASTX727 combination.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11770199	Mice were treated every 3 or 4 d for 4 times.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Mice", "were", "treated", "every", "3", "or", "4", "d", "for", "4", "times", ...
PMC9429973	E. Kugler, S. Madiwale, D. Yong, Y. Birger, J. A. I. Thoms, D. B. Sykes, M. Yassin, N. Aqaqe, A. Rein, H. Fishman, I. Geron, C.-W. Chen, B. Raught, Q. Liu, M. Milyavsky, J. Pimanda, G. G. Privé, S. Izraeli Institute of Hematology, Davidoff Cancer Center, Rabin medical center, Petah Tikva; Department of Human Molecular Genetics and Biochemistry, Sackler Medical School, Tel Aviv University, Tel Aviv, Israel; Department of Biochemistry, University of Toronto, Toronto, Canada; The Rina Zaizov Pediatric Hematology and Oncology Division, Schneider Children’s Medical Center, Petach Tikva, Israel; Adult Cancer Program, Lowy Cancer Research Centre; Faculty of Medicine, UNSW Sydney, Sydney, Australia; Center for Regenerative Medicine, Massachusetts General Hospital, Boston; Harvard Stem Cell Institute, Cambridge, United States of America; Department of Pathology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; Department of Systems Biology, Beckman Research Institute, City of Hope, Duarte; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston; City of Hope Comprehensive Cancer Center, Duarte, United States of America; Princess Margaret Cancer Centre, University Health Network, Toronto, Canada Background: The ETS transcription factor ERG is essential for the maintenance of hematopoietic stem cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11261875	The upregulation of GLUT expression can play a vital role in the acquisition of imatinib resistance by GIST and cell survival.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "upregulation", ...
PMC11271278	Source data for the (H) are provided as a Source Data file.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Source", "data", "for", "the", "(", "H", ")", "are", "prov...
PMC11087055	Aphidicolin (SIGMA, A0781), dissolved in DMSO (SIGMA, B23151), was added to Tyrode’s solution to a final concentration of 0.1–100 μM. Embryos were isolated, and soaked in Tyrode’s solution with either 0.3% DMSO (control), or various concentrations of aphidicolin for 15 minutes at 37 °C.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5811757	MTT assay was used to assess viability of CRISPR/Cas9 treated cells in the presence of various concentrations of doxorubicin.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "MTT", "assay", "was", "used", ...
PMC11739504	Next, minced tissue was incubated for 30–40 min in the 37 °C incubator with 0.05% Trypsin–EDTA (LS015-01; Welgene).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC5308810	We first analyzed the phenotypic heterogeneity of A2780 and its doxorubicin-resistant cell lineage (A2780/ADR) by screening for the presence of live (non-fixed) cell subsets that express cell-surface CSC markers (CD44, CD133, and CXCR4) [26, 30–35].	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC7338939	A375 human melanoma cell line originated from a culture of a lymph node metastasis of a melanoma patient (31), and NA8 (originated from the culture of malignant melanoma) was a gift from Dr. Giulio Spagnoli (University Hospital of Basel, Switzerland).	[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "...
PMC9878562	The observation suggests that the C-terminus is necessary for ACKR3 activity during VAL cell migration.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O" ], "tokens": [ "The", "observation", "suggests", "that", "the", "C-termi...
PMC11680982	HER2 expression in HR/HER2-0 and HR/HER2-low breast cancer subtypes by fluorescence quantitative PCR assay, P = 0.015, *P < 0.05; n = 3.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11155445	From these analyses it was concluded that the seven acyl thiourea exhibit potent anti-inflammatory activity and activity was found dose-dependent, thus by increasing the concentration, the anti-inflammatory activity of the acyl thiourea increases.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11650848	Together, this study sheds light on the regulation of this interesting and epigenetically sensitive gene, as well as providing insights into the potential biological mechanism explaining the beneficial effect of maternal FA during pregnancy on the epigenome and neurodevelopment in the child.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11298021	These cells were subsequently transfected with 50 nM of FAM-labeled Scramble using TurboFect transfection reagent (Thermo Fisher, USA) for 48 hours.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11772585	Collectively, these findings support the conclusion that inhibiting METTL1 suppresses cSCC cell survival, migration, and invasion.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Collectively", ",", "these", "fin...
PMC10551595	The RMSD values were 1.65, 1.16, 0.80 and 0.57 Å, respectively, which confirmed docking accuracy.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "RMSD", "values", "were", ...
PMC11747467	A total of 12 basal and 19 luminal MIBC samples were determined.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "total", "of", "12", "basal", "and", "19", "luminal", "MIBC", "samples...
PMC11706297	In particular, 3,5-diaryl-4,5-dihydro-1H-pyrazole derivatives have been extensively screened for a wide range of biological activities, including anticancer activity [19–22].	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", ...
PMC11127909	B Scatterplot showing the negative correlation between EFHD1 and C-caspase 3 expression, N = 32.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "B", "Scatterplot", "showing", "the", "negative", "corr...
PMC11286266	Under basal conditions, ATF6α predominantly existed as a high mobility monomer in both 2K-parental and 2K-CRT∆ cells, with the appearance of an even faster-migrating processed N-ATF6α form in 2K-CRT∆ cells, consistent with the findings presented in Figure 3B.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11512230	ES36 were grown on coverslips (2 × 10 cells per coverslip) covered with 1% laminin 24 h prior to treatment.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "ES36", ...
PMC10213179	Various strategies have been employed to target and modulate EphA2 activation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Various", "strategies", "have", "been", "employed", "to", "target", "and", "modulate", ...
PMC11357960	Flow-cytometry dot plots showed the strategy for gating peripheral blood lymphocyte cells with CD69 and Annexin V phenotype. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Flow-cytometry", "dot", "plots", ...
PMC6442998	Blue arrows: KIT inhibition by imatinib led to downregulation of major pathways such as MAPK/ERK or PKB controlling expression of viability factors.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Blue", ...
PMC11566417	a Results from qPCR analysis were plotted on a heatmap to show transcript expression in primary and immortalized lines at p10 and p20.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "a", ...
PMC11345828	The mixtures were incubated for 3 h and signal (Delta F) was measured on the Biotek Cytation 3 equipped with a filter cube containing an Ex 340/30 nM Em 620/10 filter and an Ex 340/30 Em 520/10 filter.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11637276	The correlation and reproducibility of the hits were the main criteria for selecting the hits; this approach has been conventionally followed in many studies [23,108–110].	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11640476	No disagreements were observed for the high confluency (Figure 1).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "No", "disagreements", "were", "observed", "for", "the", "high", "confluency", "(...
PMC9429973	Several heterozygous hypomorphic/dominant negative (DN) variants of CARD11 have demonstrated a loss of protein function, exhibiting high penetrance and variable expressivity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11474209	This target-responsive and signal-amplification technology allowed the creation of colorimetric biosensors.(Fe₃O₄@SiO₂) and (PDA/CuNPs)water samples0.05 μg/LSandwich-type composites were magnetically separated by Fe3O4@SiO2PDA/CuNPs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "targ...
PMC11686380	These results obtained from knockout mice highlight the importance of GAP43 in neuronal connectivity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "results", "obtained", "from", "knockout", "mice", "highlight"...
PMC9429973	Results: Characteristics of transplantation were presented in Table-1.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Results", ":", "Characteristics", "of", "transplantation", "were", "presented", "in", "Table-1", "." ] ...
PMC11802929	For Supplementary Fig. 8b, Dominant TCRs were removed to test whether our result is biased by large clones.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "Supplementary", "Fig.", "8...
PMC11703896	The extracted rapamycin showed a peak at retention time 6.189 min similar to the peak observed in the standard rapamycin.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "extracted", "rapamyci...
PMC11650848	The diagonal line of squares in the middle is the Functional OR Genomic Element Database (FORGEdb) scores which are out of 10 and is used to predict if genetic variants are likely to be regulatory elements.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11656657

For the stimulation assays with 1A7 anti-idiotypic antibody, non-transduced (NT) T-cells and CAR.GD2 T-cells were incubated with 0.5 ng/mL of 1A7 anti-idiotypic antibody for 72 h. The 1A7 antibody was used to mimic stimulation by the tumor-associated antigen disialoganglioside GD2.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10958426

GO enrichment analysis of DEGs with high CNV-expression correlation (DEGCNV) and DEGs with low CNV-expression correlation (DEGreg).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "GO", "enrichment", ...

PMC11012012

Later, Yigit et al. (2016) reported that upon transplantation of an aggressive murine B220+ CD5+ CLL cell clone, TCL1-192, into SCID mice, one injection of an anti-SLAMF6/CD352 monoclonal antibody abrogated tumor progression in the spleen, bone marrow, and blood, but not in the peritoneal cavity or omentum .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11674441

Indeed, the IFN-γ ELISpot data for BC5 showed that when HLA class II-restricted neoantigen peptide-pulsed DCs and CD4-positive T cells and CD8-positive T cells obtained after Neo-P DCs vaccination were co-cultured, the degree of lymphocyte activation increased even further than the sum of activation levels when they were co-cultured separately.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10547921

Continuous DNA damage is caused by cross-linking between DNA chains, which leads to cell cycle arrest in the G2/M phase and cell apoptosis, thus exhibiting a powerful cytotoxic effect.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10024132

Briefly, tumor cells were first stained with PKH26 (Sigma) and 5(6)-carboxyfluorescein diacetate succinimidyl ester (CFSE; Invitrogen).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Briefly", ",...

PMC11740207

Comparative molecular profiling of VSELSCs or VSLSLCs with existing datasets from early human embryonic stages and somatic cells is essential to elucidate their unique and shared characteristics.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11748618

Each data point (pink) represents a meQTL in the chromosome 1 region in linkage disequilibrium (r = 1) with rsrs72999655-A-G. The vertical bars show whether the meQTL is associated with hypermethylation (red) or hypomethylation (blue).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11697703

FACS purifications were performed by the Stanford Shared FACS Facility.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "FACS", "purifications", "were", "performed", "by", "the", "Stanford", "Shared", "FACS", "Facilit...

PMC11737091

L-N) Diagnostic ROC analysis with the AUC of DBF4 in ccRCC. (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "L-N", ")", "Diagnostic", "ROC", "analysis", "with", "the", "AUC", "of...

PMC9429973

The initial diagnosis of ETP-ALL was based on the results of bone marrow cytology and flow cytometry immunophenotype.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "initial", "diagnosis", "of", "E...

PMC6034753

Subsequently, after washing, cells were incubated with Alexa 488 (CEF and DF-1 cells)/ 568 (MSB-1 cells)-conjugated goat anti-rabbit antibodies.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O" ], ...

PMC11721587

The cells were scraped off the plate and washed with cold PBS twice and resuspended with cold Farnham lysis buffer [5 mM Pipes (pH 8.0), 85 mM KCl, 0.5% NP-40, and 1× complete protease inhibitors cocktail].

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11389534

UBL modifications participate in the modulation of immune responses by specifically targeting immune receptors, adaptors, enzymes and transcriptional factors.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "UBL", "modifications", ...

PMC6892818

For detection of intracellular ROS levels, cells were treated with 1 μM H2DCFDA (Thermo Fisher Scientific) for 30 min, fluorescence measurements (relative fluorescence units, RFU) were taken spectrophotometrically and results expressed as fold increase in RFU, as described in detail previously.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9532503

For example, it is well established that the absence of core fucose leads to increased ADCC activity .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "example", ",", "it", "is", ...

PMC6160470

Although the tested compounds did affect Akt signalling pathway, this did not ultimately alter P-gp expression and is probably not the underlying mechanism of action.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...

PMC7887261

Sensitive DNA damage assays by flow cytometry were performed as previously described.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Sensitive", "DNA", "damage", "assays", "by", "flow", "cytometry", "were", "perfo...

PMC9429973

We show that spleen function is partially preserved in many adults with SCD.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", "show", "that", "spleen", "function", "is", "partially", "preserved", ...

PMC11082662

Cancer has the highest mortality rate among gynecological cancers and poses a serious threat to women’s lives.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cancer", "has", "the", "highest", "mor...

PMC10809689

Significant variation for the PMA group compared to the control group was reported (p = 0.04) (Fig. 9 (a.)).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...

PMC11298021

Expression of PI3K, AKT, mTOR, and S6KB1 genes in Jurkat cells.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "Expression", "of", "PI3", "K", ",", "AKT", ",", ...

PMC11665555

In addition, the Markus Riester high-risk cohort BCa dataset (n = 93) revealed that OXCT1 was significantly expressed in invasive disease (pT4) while HMGCS2 was downregulated at higher disease stages, showing a correlation with muscle invasive disease (Figure 1, A and B) (23).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11461874

The precipitate was resuspended in SDS-PAGE sample buffer [10 mM Tris-HCl, 2 mM EDTA, 2% SDS, 6% glycerol, 50 mM DTT, 0.02% CBB R-250; pH 6.8] and incubated at 95 °C for 5 min, used as “nuclear fraction”.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9895440

Then the drugs were added to the cells, mixed rapidly and incubated again.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Then", "the", "drugs", "were", "added", "to", "the", "cells", ...

PMC9429973

Network and Pathway Enrichment Analysis MMP9 (degree=9) and CCNA2 (degree=7) showed significant importance (Fig 2A).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Network", "and", ...

PMC11791264

The consensus SETD7 recognition sequence, the lysines targeted for methylation by SETD7 in known substrates, and the methylated lysine are shown in red in each case.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9926039

An in vitro trans well migration assay was performed by uncoated 8 μm pore size membranes (SPL Life Sciences, South Korea).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC8922418

One of the most significant challenges in the treatment of AIDS is eliminating the latent reservoir in HIV-1 infected cells.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "One", "of", "the", "mo...

PMC6650823

Highlighted by Simona Collina Riboswitches are regulatory, noncoding RNA aptamers that regulate gene expression by binding to specific small molecules.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Highlighted", "by", ...

PMC10671321

Some data suggest that ColQ/MuSK/LRP4 interaction impacts the activity of signalling pathways leading to specific mRNA regulation, the number and the size of AChR clusters, as well as membrane levels of MuSK .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11360263

Evidence from in vitro and in vivo data indicated that HCMV might play a role in the onset or progression of breast cancer .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Evidenc...

PMC11705630

We then assessed the expressions of GLDC and ISGF3 in xenografted tumor tissues and confirmed decreased GLDC and increased IRF9 and STAT2 expressions (Fig. 8D-E).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11216402

The combined differential expression of these TF genes and the identification of their TF binding sites as the largest signals in predictive sequence modeling of the chromatin accessibility profiles strongly suggest that the variability in activation of this small set of TFs is responsible for driving the EMT program.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11394112

We confirmed the genotype by PCR using the following primer sets (IL6, 5′ AGG GAG AGC CAG AAC ACA GA 3′ and 5′ TGC AGC TTA GGT CGT CAT TG 3′; CSF2, 5′ ACC TGC CTA CAG ACC CG 3′ and 5′ AGT GCT GCT TGT AGT GGC 3′; IL3, 5′ AAT CTC CTG CCA TGT CTG C 3′ and 5′ CCA GTC ACC GTC CTT GAT ATG 3′; KITLG, 5′ CAA GGA CTT TGT AGT GGC ATC TG 3′ and 5′ CAA CAG GGG GTA ACA TAA ATG G 3′).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11411131

CGCs were prepared from 7-day-old mouse pups.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CGCs", "were", "prepared", "from", "7-day-old", "mouse", "pups", "." ] } ]

PMC11731161

A–D NCI-H929 and MM.1S cells were transfected with the tet-on-shRNA either with control sequence (NC) or sequences targeting USP7 (#1 and #2), cells were treated with 1ug/ml DOX for 48 h, USP7 (A and B) and XPO1 (A and C) protein levels were analyzed by immunoblotting and were quantitatively analyzed.

[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...

PMC9926039

The ΔΔCt value was calculated by obtaining the difference between the ΔCt values of the treated and untreated cells (ΔΔCt = ΔCt (treated cell)-ΔCt (untreated cell).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11075223

For example, Cimicifugae Rhizoma has a good effect on treating vertigo with compatibility of Polygonatum sibiricum Red .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "example", ",", "Cimicifugae", "...

PMC10604092

Data were analyzed statistically using Student’s t-test or Welch’s t-test on the basis of the result of an F test (GraphPad Prism 9 version 9.5.1; GraphPad Software, San Diego, CA, USA).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC8633974

Statistical calculations set type I error cut-off α = 0.05 and were performed using GraphPad Prism v7.0a or 9 for Mac OS X (GraphPad Software, San Diego, California USA, www.graphpad.com).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC5308810

A representative graph of six independent experiments was performed.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "representative", "graph", "of", "six", "independent", "experiments", "was", "performed", "." ] }...

PMC11594641

Cell invasion was studied using the QCM ECMatrix Cell Invasion Assay (Merck Millipore, Burlington, MA, USA) according to the manufacturer’s protocol.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9454178

As expected, the results showed that THZ1 treatment led to a profound reduction in tumour volume and weight, corroborating the tumour inhibition effect in vitro (Fig. 4A).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11310713

(G), and bone volume/total volume (BV/TV) (H) in GTB or pharmaceutical hormone-treated OVX rats compared to ovary-intact and OVX rats.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9910796

However, the closest relatives of ASFV, the amoeba-infecting faustovirus , pacmanvirus and kaumoebavirus , together with the mollusk-infecting abalone asfa-like virus (AbALV) , encode homologs of polyproteins pp220 and pp62 as well as ASFV protease.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC8633974

A gRNA library was screened against a panel of HIV-1 molecular clones by co-transfection into HEK293FT cells.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O" ], "tokens": [ "A", "gRNA", "library", "was", "screened"...

PMC9164404

E Fluorescence distribution of Abplatin@Cy5.5 at 12 h in different focal planes of 3D tumor sphere, scale bar = 100 µm.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "E", "Fluores...

PMC11783017

Next, 5 mg of the previously synthesized Cis/Mn@Lipo-IL11 (quantified by cisplatin) and 5 mg of NHWD-870 were added to 250 mg of PGP (3 %/1.5 %).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10213199

These results provide enlightenment to further improve our understanding of the specific active ingredients in traditional Chinese medicines.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "results", "provide", "enlightenment...

PMC11394227

The expressions of PERK, BiP, and CHOP protein in CHO-PAb cells increased by 1.29 times, 1.56 times, and 1.32 times, respectively, while those in CHO-PAb-QS cells increased by 1.15 times, 1.06 times, and 1.43 times, respectively.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC10507284

Hence, we can roughly infer that the downregulation of TROAP could significantly attenuate the proliferation, migration, and invasion ability of STS cells.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...

PMC11718109

Quantification of vesicle diameter was performed using randomly sampled images from clustered vesicles in classical synapses and bouton-like structures for DA neurons, and large droplets in COS7 cells.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", ...

PMC11568601

After rinsing three times with PBS, secondary antibodies were added, and the mixture was incubated for 1 h. Finally, DAB staining solution (Beyotime Biotech.,

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9792775

Growth curves generated with OD450 data with the CCK8 assay for A-204 cells treated with LFU and PTX. (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Growth", "curves", "generated"...

PMC11738017

The dotted black line represents the starting cell viability without the addition of TCE.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "dotted", "black", "line", "represents", "the", "starting", ...

PMC10988555

These results demonstrate that complexes may be internalized by an active transport, as reported by other authors, but they are also able to enter cells by passive diffusion.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9817179

A low 405 nm activation power was used to ensure sufficiently sparse activation of PA-JF646-labeled proteins and allow for SPT.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "low", "405", "nm"...

PMC11095939

Protein concentrations were quantified using a BCA Protein Assay Kit.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Protein", "concentrations", "were", "quantified", "using", "a", "BCA", "Protein", "Assay", "Kit"...

PMC11279397

This enabled us to integrate these virus-associated target genes with the Perilla-related target genes for subsequent analysis.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "enabled", "us", "to", "integrate", ...

PMC9268183

The field of ethnobotany focuses on documenting traditional knowledge and uses associated with plants, providing baseline information for plant screenings to be used during the treatment and/or prevention of certain diseases .

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11155445

Compounds (101a–c) also showed prominent activity against HepG2 having cell viability of 35.01%, 37.31%, and 39.22%, respectively, while compounds (101e and 101f) were found least active against all tested cancer cell lines having high cell viability (63.75–82.81%) (Fig. 37).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC9454852

cDNA then was obtained utilizing the Transcriptor First Strand cDNA Synthesis Kit (Roche Diagnostics GmbH, Penzberg, Germany).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "cDNA", "then", "w...

PMC9587866

This was achieved through GalaxyRefine database, which further improved the structural and topical features of EYA3 protein model.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "was", "achieved", "throug...

PMC9429973

The primary objective is to determine the safety and tolerability (phase 1) and overall response rate (ORR, defined as CR+mCR) (phase 2) of Ven+ASTX727 combination.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11770199

Mice were treated every 3 or 4 d for 4 times.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Mice", "were", "treated", "every", "3", "or", "4", "d", "for", "4", "times", ...

PMC9429973

E. Kugler, S. Madiwale, D. Yong, Y. Birger, J. A. I. Thoms, D. B. Sykes, M. Yassin, N. Aqaqe, A. Rein, H. Fishman, I. Geron, C.-W. Chen, B. Raught, Q. Liu, M. Milyavsky, J. Pimanda, G. G. Privé, S. Izraeli Institute of Hematology, Davidoff Cancer Center, Rabin medical center, Petah Tikva; Department of Human Molecular Genetics and Biochemistry, Sackler Medical School, Tel Aviv University, Tel Aviv, Israel; Department of Biochemistry, University of Toronto, Toronto, Canada; The Rina Zaizov Pediatric Hematology and Oncology Division, Schneider Children’s Medical Center, Petach Tikva, Israel; Adult Cancer Program, Lowy Cancer Research Centre; Faculty of Medicine, UNSW Sydney, Sydney, Australia; Center for Regenerative Medicine, Massachusetts General Hospital, Boston; Harvard Stem Cell Institute, Cambridge, United States of America; Department of Pathology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; Department of Systems Biology, Beckman Research Institute, City of Hope, Duarte; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston; City of Hope Comprehensive Cancer Center, Duarte, United States of America; Princess Margaret Cancer Centre, University Health Network, Toronto, Canada Background: The ETS transcription factor ERG is essential for the maintenance of hematopoietic stem cells.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11261875

The upregulation of GLUT expression can play a vital role in the acquisition of imatinib resistance by GIST and cell survival.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "upregulation", ...

PMC11271278

Source data for the (H) are provided as a Source Data file.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Source", "data", "for", "the", "(", "H", ")", "are", "prov...

PMC11087055

Aphidicolin (SIGMA, A0781), dissolved in DMSO (SIGMA, B23151), was added to Tyrode’s solution to a final concentration of 0.1–100 μM. Embryos were isolated, and soaked in Tyrode’s solution with either 0.3% DMSO (control), or various concentrations of aphidicolin for 15 minutes at 37 °C.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC5811757

MTT assay was used to assess viability of CRISPR/Cas9 treated cells in the presence of various concentrations of doxorubicin.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "MTT", "assay", "was", "used", ...

PMC11739504

Next, minced tissue was incubated for 30–40 min in the 37 °C incubator with 0.05% Trypsin–EDTA (LS015-01; Welgene).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC5308810

We first analyzed the phenotypic heterogeneity of A2780 and its doxorubicin-resistant cell lineage (A2780/ADR) by screening for the presence of live (non-fixed) cell subsets that express cell-surface CSC markers (CD44, CD133, and CXCR4) [26, 30–35].

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...

PMC7338939

A375 human melanoma cell line originated from a culture of a lymph node metastasis of a melanoma patient (31), and NA8 (originated from the culture of malignant melanoma) was a gift from Dr. Giulio Spagnoli (University Hospital of Basel, Switzerland).

[ { "tags": [ "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "...

PMC9878562

The observation suggests that the C-terminus is necessary for ACKR3 activity during VAL cell migration.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O" ], "tokens": [ "The", "observation", "suggests", "that", "the", "C-termi...

PMC11680982

HER2 expression in HR/HER2-0 and HR/HER2-low breast cancer subtypes by fluorescence quantitative PCR assay, P = 0.015, *P < 0.05; n = 3.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11155445

From these analyses it was concluded that the seven acyl thiourea exhibit potent anti-inflammatory activity and activity was found dose-dependent, thus by increasing the concentration, the anti-inflammatory activity of the acyl thiourea increases.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11650848

Together, this study sheds light on the regulation of this interesting and epigenetically sensitive gene, as well as providing insights into the potential biological mechanism explaining the beneficial effect of maternal FA during pregnancy on the epigenome and neurodevelopment in the child.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11298021

These cells were subsequently transfected with 50 nM of FAM-labeled Scramble using TurboFect transfection reagent (Thermo Fisher, USA) for 48 hours.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC11772585

Collectively, these findings support the conclusion that inhibiting METTL1 suppresses cSCC cell survival, migration, and invasion.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Collectively", ",", "these", "fin...

PMC10551595

The RMSD values were 1.65, 1.16, 0.80 and 0.57 Å, respectively, which confirmed docking accuracy.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "RMSD", "values", "were", ...

PMC11747467

A total of 12 basal and 19 luminal MIBC samples were determined.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "total", "of", "12", "basal", "and", "19", "luminal", "MIBC", "samples...

PMC11706297

In particular, 3,5-diaryl-4,5-dihydro-1H-pyrazole derivatives have been extensively screened for a wide range of biological activities, including anticancer activity [19–22].

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "In", ...

PMC11127909

B Scatterplot showing the negative correlation between EFHD1 and C-caspase 3 expression, N = 32.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "B", "Scatterplot", "showing", "the", "negative", "corr...

PMC11286266

Under basal conditions, ATF6α predominantly existed as a high mobility monomer in both 2K-parental and 2K-CRT∆ cells, with the appearance of an even faster-migrating processed N-ATF6α form in 2K-CRT∆ cells, consistent with the findings presented in Figure 3B.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11512230

ES36 were grown on coverslips (2 × 10 cells per coverslip) covered with 1% laminin 24 h prior to treatment.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "ES36", ...

PMC10213179

Various strategies have been employed to target and modulate EphA2 activation.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Various", "strategies", "have", "been", "employed", "to", "target", "and", "modulate", ...

PMC11357960

Flow-cytometry dot plots showed the strategy for gating peripheral blood lymphocyte cells with CD69 and Annexin V phenotype. (

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Flow-cytometry", "dot", "plots", ...

PMC6442998

Blue arrows: KIT inhibition by imatinib led to downregulation of major pathways such as MAPK/ERK or PKB controlling expression of viability factors.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Blue", ...

PMC11566417

a Results from qPCR analysis were plotted on a heatmap to show transcript expression in primary and immortalized lines at p10 and p20.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "a", ...

PMC11345828

The mixtures were incubated for 3 h and signal (Delta F) was measured on the Biotek Cytation 3 equipped with a filter cube containing an Ex 340/30 nM Em 620/10 filter and an Ex 340/30 Em 520/10 filter.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11637276

The correlation and reproducibility of the hits were the main criteria for selecting the hits; this approach has been conventionally followed in many studies [23,108–110].

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11640476

No disagreements were observed for the high confluency (Figure 1).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "No", "disagreements", "were", "observed", "for", "the", "high", "confluency", "(...

PMC9429973

Several heterozygous hypomorphic/dominant negative (DN) variants of CARD11 have demonstrated a loss of protein function, exhibiting high penetrance and variable expressivity.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...

PMC11474209

This target-responsive and signal-amplification technology allowed the creation of colorimetric biosensors.(Fe₃O₄@SiO₂) and (PDA/CuNPs)water samples0.05 μg/LSandwich-type composites were magnetically separated by Fe3O4@SiO2PDA/CuNPs.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "targ...

PMC11686380

These results obtained from knockout mice highlight the importance of GAP43 in neuronal connectivity.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "results", "obtained", "from", "knockout", "mice", "highlight"...

PMC9429973

Results: Characteristics of transplantation were presented in Table-1.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Results", ":", "Characteristics", "of", "transplantation", "were", "presented", "in", "Table-1", "." ] ...

PMC11802929

For Supplementary Fig. 8b, Dominant TCRs were removed to test whether our result is biased by large clones.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "Supplementary", "Fig.", "8...

PMC11703896

The extracted rapamycin showed a peak at retention time 6.189 min similar to the peak observed in the standard rapamycin.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "extracted", "rapamyci...

PMC11650848

The diagonal line of squares in the middle is the Functional OR Genomic Element Database (FORGEdb) scores which are out of 10 and is used to predict if genetic variants are likely to be regulatory elements.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...