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Amyotrophic lateral sclerosis (als) is an adult - onset motor neuron disease is characterized by selective degeneration of motor neurons in the brain and spinal cord, resulting in progressive paralysis of limb, facial, and respiratory muscles and death within few years [1, 2]. The pathological hallmarks of als are the ...
Two american scientists (patients 1 and 2) lived and worked in the village of bandafassi in southeastern senegal in august 2008 while performing a mosquito - sampling project in surrounding villages . Patients 1 and 2 were men (36 and 27 years of age, respectively), and both had received the yellow fever 17d vaccine be...
Among cancers affecting women, cervical cancer has the second highest occurrence worldwide, with an incidence in 2008 of 529,800 cases (14.5% in developed countries and 85.5% in developing countries) and 275,000 estimated deaths . Infection of cervical epithelial cells with high risk human papillomavirus (hpv) is the m...
With the use of emd, protective barrier between attached gingiva and transmucosal zirconia abutment may be enhanced leading to final esthetic results with implants . Zirconia has adequate mechanical properties similar to those of stainless steel, such as high flexural and tensile strength, high resistance to abrasion a...
In november 2013, the us food and drug administration (fda) created shock - waves around the world by issuing a cease and desist order against 23andme, the dominant provider of direct - to - consumer (dtc) genomic services.1 23andme, in common with several other companies worldwide, offered genetic testing services dir...
Tooth brushing plays an important everyday role in personal oral hygiene and effective plaque removal . Toothbrushes may become heavily contaminated with microorganisms and these microorganisms may originate not only from the oral cavity but also from the environment where the toothbrushes are stored . This contaminati...
Since ancient times, electrical stimulation has been used to modulate the nervous system and to treat some neurological disorders (rossi, 2003). Scribonius largo, physician of the roman emperor claudius, in his text compositiones medicamentorum (46 ad) suggested the application of electric ray (torpedo torpedo and torp...
Responses to applied medicines can be different and personalized treatment requires collection of the maximum number of data . One of them is the metabolic profile of the patient reflecting the present state of the organism . For this purpose spectroscopic techniques are applied, such as raman spectroscopy, mass spectr...
The ewing's sarcoma / primitive neuroectodermal tumour (es / pnet) family of tumours is part of a rare group of malignant neoplasms with small round - cell morphology . Es / pnet is an uncommon primary malignancy of the bone primarily affecting children and young adults with more than 80% of patients being younger than...
Squamous cell carcinoma (scc) is the most common malignant mucosal neoplasm to affect the head and neck region . Occasionally, variants of scc may be encountered, which includes verrucous, exophytic or papillary, spindle cell (sarcomatoid), basaloid and adenosquamous types that make up an aggregate of 10%15% of all scc...
After the pediatrician and the newborn health screener technician, pediatric otolaryngologists and audiologists are parents' first professional contact . Typically, after the diagnosis of hearing loss, they make the referrals to the early education specialists . Training for medical / audiological professionals typical...
Hyperglycemia and insulin resistance are common in critically ill patients and more pronounced among patients having sepsis, burns, trauma, and cardiothoracic surgery.1 hyperglycemia was previously considered an adaptive response essential for survival and was not routinely controlled in intensive care units (icus).2,3...
Oral cancer is commonly preceded by premalignant lesions and conditions grouped under common terminology as potentially malignant disorders . The precursor lesions that precede oral cancer are defined as an altered epithelium that shows a variety of cytological and architectural changes that have been traditionally bro...
Henoch - schnlein purpura (hsp) is a common systemic vasculitic disorder that occurs during hildhood and its course is often self - limiting (1, 2). Multiple studies have reported less frequent but poorer outcomes in adult hspn (1, 2) and there have been a few data on elderly - onset patients (3). Iga nephropathy is us...
Breast cancer is the most common cancer among women and its incidence is increasing . However, its mortality decreases with better screening programs, public education, and medications . Disease - free survival and overall survival depend on multiple factors, including the stage of the disease, hormone receptor status,...
Punjab (india) has 3 main wetlands, i.e. Harike, kanjli and ropar wetlands which are included in ramsar list of international importance . Harike wetland (31 17 n latitude and 75 12 e longitude) is the largest freshwater wetland (in northern india) of 4100 ha area with beas and sutlej as primary inflows . It is a habit...
In drug discovery projects, the three - dimensional (3d) structure of the receptor is not always available . In such cases, pharmacophore model building, 3d quantitative structureactivity relationship (qsar), comparative molecular field analysis (comfa),(1) and ligand - based virtual screening all depend on a good algo...
Esthesioneuroblastoma also called olfactory neuroblastoma is a rare malignant neuroectodermal tumor of the sinonasal tract region, first described by berger et al . In 1924 . According to the world health organization, olfactory neuroblastoma is defined as a malignant neuroectodermal tumor, that is, assumed to originat...
Hepatocellular carcinoma (hcc) is the sixth most common malignancy worldwide and the third most common cause of global cancer related mortality [1, 2]. Hcc burden disproportionately impacts developing countries and males; as of 2008, 85% of cases occurred in africa and asia, with worldwide male: female sex ratio of 2.4...
Depression, a severe psychiatric disorder [1, 2], affects up to 20% of the population in the us within their lifetime and is more prevalent in women than men [36]. Although depression has been studied for decades, its cellular and molecular mechanisms still remain largely unknown . As many as 3040% of patients with maj...
The calcifying epithelial odontogenic tumor (ceot) is also known as pindborg tumor . The dutch pathologist, dr . Jens jorgen pindborg, described and designated ceot as a distinct pathologic entity in 1955 . It is a benign, locally invasive neoplasm that constitutes about 1% of all odontogenic neoplasms . Ceot usually p...
Type 1 diabetes mellitus (dm1) affects nearly three million americans.1 it is a challenging disease to manage, often requiring complex medical regimens and significant effort from both the clinician and the patient . The first manifestation of beta cell loss is loss of first - phase insulin secretion (peak levels of in...
The serine / threonine kinase akt (pkb / c - akt) promotes cell growth (i.e., accumulation of cell mass) predominantly through activation of complex 1 of the mammalian target of rapamycin (mtorc1) (sarbassov et al ., mtorc1 is regulated by both nutrients and growth factors and plays a conserved role in cell growth cont...
Vascular complications after percutaneous renal biopsy are uncommon with macroscopic hematuria occurring in up to 3.5% of patients . Most are self - limited with blood transfusion needed in only about 0.9% and radiologic intervention in 0.6% cases . The pathology seen on angiography in most cases is either renal arteri...
Superior mesenteric artery (sma) syndrome, also called wilkie's syndrome, is a rare clinical phenomenon believed to be caused by compression of the third portion of the duodenum by the overlying superior mesenteric artery . An abnormally acute aorta - sma angle, or high retroperitoneal attachment of the ligament of tre...
Nowadays, the number of individuals with cerebral palsy (cp) that survive into adulthood has increased, since life expectancy of children with cp has increased dramatically and their mortality rate has significantly reduced (1). Consequences of cerebral palsy in adulthood can affect physical, psychological capabilities...
They work by competitively inhibiting hmg - coa reductase, the enzyme involved in the conversion of hmg - coa to mevalonate, an early rate - limiting step in the synthesis of cholesterol in the liver . Besides the lipid lowering effect of statins in the primary and secondary prevention of coronary artery diseases and h...
Statistically, urbanization levels are higher in countries that have higher income, and with many studies suggesting a strong correlation between urbanization and income level, it has been a long - standing notion that urbanization promotes economic growth . Because of this, accelerating urbanization has been viewed as...
They consist of fibrous giant cells that are specifically designed for efficient nerve - controlled shortening . To switch the contractile machinery on and off, these cells raise and lower their cytoplasmic ca concentration (for review see melzer et al ., 1995). To allow the concentration increase to occur with suffici...
Esophageal achalasia is a primary esophageal motility disorder characterized by lack of peristalsis and failure of the lower esophageal sphincter (les) to relax in response to swallowing . However, degeneration and loss of ganglion cells in the auerbach s nerve plexus have been reported and result in esophageal motor d...
Atherosclerosis (ath) is an inflammatory disease characterized by intense immunological activity that involves the formation of lesions in the arteries and is characterized by lipid accumulation, inflammation, cell death, and fibrosis . Recruitment of monocytes and lymphocytes from the peripheral blood to the intima of...
Hypertension is more severe and associated with more severe sequelae in blacks when compared with subjects of caucasian extraction [25]. Studies have also shown that black subjects have lower plasma renin levels [68]. It is thought that black subjects have inappropriately elevated levels of aldosterone relative to plas...
, the medical faculty and deans offices cannot operate in isolation but must establish links with existing services run by the university, the city or the country, churches and so on . For example, kids (children at university), an initiative by the university of heidelberg, the german national association for student ...
Moreover, direct injury, secondary insult due to post - traumatic increase of icp or decrease in cerebral perfusion pressure are well recognized as potential causes of increasing mortality and morbidity.467) decompressive craniectomy (dc) is an important method to decreased icp,9) and dc is widely performed throughout ...
Raman scattering from the silicon (si) nanostructures (nss) has been extensively studied in recent years [1 - 4]. Observed raman line - shapes from the si nss are asymmetrically broadened and red - shifted from its counterpart for the bulk si . Most authors have fitted the first - order experimental raman band to an as...
The three data components of the analysis are age- and sex - specific mortality rates, age- and sex - specific population estimates by weight status, and age- and sex - specific diabetes incidence rates . Mortality rates were calculated based on number of deaths by sex and age from the national vital statistics system ...
Sexually transmitted / transmissible infections (stis) also referred to as sexually transmitted diseases (stds) or venereal diseases (vds) are infections that can be transmitted from one person to another through sex (vaginal intercourse, anal sex, or oral sex). Sexually transmissible infections (stis) are common . A n...
Presynaptic monoamine transporters such as the dopamine transporter (dat) regulate signal transduction by controlling neurotransmitter concentrations available for receptor binding at the postsynaptic site . Disturbances in dat function have been implicated in a variety of disorders including schizophrenia, major depre...
About 50% of patients with a diagnosis of non - small cell lung carcinoma exhibit metastatic disease at the time of diagnosis . The preferential sites of extrapulmonary spread are the lymph nodes, liver, brain, adrenal glands, and bones . A 51-year - old smoker was diagnosed with a poorly differentiated non - small cel...
Nowadays, one - dimensional nanostructural materials (nanorods, nanowires, nanobelts and nanotubes) have attracted heightened attention because of their potential applications in nanodevices and functional materials . Continuous effort has been devoted to the investigation on the crystalline phases of the layered trans...
As a small molecule probe, aptamers are composed of short, single - stranded oligonucleotides (rna or ssdna) ranging from 30 to 60 bases . Similar to protein antibodies on the basis of their three - dimensional structures, aptamers specifically recognize and bind to their targets with high sensitivity and specificity ....
Endodontically treated teeth, with a large amount of coronal tooth structure missing, frequently require the placement of a post inside the root canal, to retain a core for definitive restoration. [13] the choice of appropriate restoration for these teeth is influenced by strength and esthetics . Depending on the clini...
Women with breast cancer who have undergone standard medical treatment, i.e., surgery, chemotherapy, and/or radiotherapy commonly experience pain as a consequence of these interventions1 . The anterior and/or lateral region of the thorax, axilla, and upper limbs are the anatomic sites most often affected by pain in suc...
Alzheimer's disease (ad) is an irreversible, progressive disorder with loss of cognitive function, particularly memory, judgment, reasoning, and perception . The disease primarily affects parts of the association cortex and deep structures including the hippocampus and basal frontal nuclei through a number of pathophys...
All experiments were conducted in lupiro village in the kilombero valley of rural southern tanzania using commercially available irs formulations of pyrethroids and organophosphates, which were combined with existing binding agent (ba) products for extending insecticide durability on llins . In this area of southern ta...
The data were collected as part of nationwide screening programs in 3 consecutive years in 2007, 2008 and 2009 . This program is regularly performed by the ministry of health and medical education and the ministry of education and training among all children entering elementary schools . Elementary education is mandato...
Zoonotic visceral leishmaniasis (zvl) is a potentially fatal disease in human, primarily in children . It is caused by leishmania infantum in which dogs, foxes, and jackals are the main reservoir hosts . Four species of the subgenus larrousius and one species of subgenus paraphlebotomus are considered as probable vecto...
There has been an increase of prevalence of obesity which is associated with several adverse health problems, including type 2 diabetes, hyperlipidemia and hypertension . The role obesity plays in the development of obesity - related disorders is complex and probably due to an interaction of genetic, nutritional and me...
Lipoma is the most common benign neoplasm of mesenchymal origin, and it is composed of mature adipose tissue without cellular atypia . Though predominantly located in subcutaneous sites, they are also found intramuscularly, retroperitoneally, and in intraosseous locations . Osseous lipomas are very rare despite the lar...
The development of strategies to preserve functional capacity of the geriatric population is therefore of paramount importance in improving elderly quality of life and reducing health care costs2 . There is growing evidence that the prevalence of malnutrition in elderly people is increasing3 . Malnutrition in the elder...
Gastric antral vascular ectasia (gave) is an uncommon cause of occult gastrointestinal (gi) bleeding and iron - deficiency anemia, accounting for 4% of nonvariceal upper gi hemorrhage.1 the clinical presentation of gave varies from a more indolent, chronic occult gi blood loss requiring serial transfusions to acute gi ...
We performed this study in the soconusco region of chiapas, mexico across nine coffee plantations ranging from 600 to 1,300 m above sea level (masl). The soconusco region is largely dominated by coffee agriculture (94%) with small forest fragments mixed throughout the coffee matrix (6%) (philpott et al . We established...
Acute myeloid leukemia (aml) is a malignant clonal disorder of immature myeloid hematopoietic cells that is the most common type of acute leukemia among adults . Reported mean age of aml patients is 60 . Some factors such as viruses, radiation, chemotherapy, benzene exposure and smoking increase risk of aml (1 - 4). Al...
A reactive leucocytosis, with a significant increase in early neutrophil precursors, exceeding 50,000/mm is referred as leukaemoid reaction . These reactions are generally benign, but may imitate more serious conditions such as chronic myelogenous leukaemia . Leukemoid reaction may be a paraneoplastic manifestation of ...
In recent years, the field of radiology has advanced from reviewing films on a view box to a digital era with viewing on a computer monitor . The digital environment has opened the doors to new image processing techniques that have capitalized on the three - dimensional (3d) datasets of computed tomography, magnetic re...
Benign primary intramural tumors of the esophagus are rare and account for approximately 2% of all esophageal tumors . Most of them are esophageal leiomyomas; less frequent are schwannomas or malignant masses such as gastrointestinal stromal tumors (gist). Endoscopic ultrasound biopsy or frozen section biopsy during th...
Generally, vesicle trafficking occurs via three important steps: vesicle budding from the donor organelle, movement towards a target organelle, and fusion . Several proteins are involved in docking and fusion of vesicles for target recognition and driving membrane fusion (malsam et al ., 2008). Among the proteins for v...
This study was approved by the university of south australia and the australian government department of veterans affairs (dva) human research ethics committees . A retrospective cohort study was undertaken from 1 july 2001 to 30 june 2008 using data from the dva health administrative claims database . The dva database...
The most common malignancies associated with malignant pleural effusions are carcinomas of the breast, lung, gastrointestinal tract, ovary and lymphomas . A 72-year old female patient presented to us with shortness of breath for the last 2 months . A contrast - enhanced computed tomography (cect) scan of her - thorax r...
While blood transfusions are commonly used for prophylaxis and treatment for acute chest syndromes and strokes in sickle cell patients, accumulation of excess iron resulting in secondary hemochromatosis remains a rare disease . Chelation is the mainstay for preventing and treating iron overload to deter potential end -...
The juvenile hemangioma (jh) is a form of capillary hemangioma which occurs during infancy at a rate of about 1 in every 200 live births . During the early stage it may resemble a common birthmark in that it is a flat, red lesion that intensifies in color when the infant strains or cries . With time it acquires an elev...
It is important to limit the block level to minimise haemodynamic changes during spinal anaesthesia . Low - dose local anaesthetics can limit the block level and induce rapid recovery from anaesthesia with minimal haemodynamic changes . Local anaesthetics - when used alone have a relatively short duration of action . T...
It typically occurs within fourteen days of aneurysmal rupture, and it is associated with significant morbidity and mortality [1, 2]. While pathophysiology remains incompletely understood, the interplay between inflammation and the innate immune response is strongly implicated . Following sah, increased blood - brain b...
A well - functioning permanent vascular access is crucial for the survival of patients on maintenance hemodialysis as it provides sufficient blood flow for dialysis . Because adequate blood flow is provided by the arteriovenous fistula (avf) with the fewest complications, avf the national kidney foundation's kidney dis...
Our case is a 37-year - old male who hails from sivagangai district, tamil nadu . The patient had minimal bleeding of 20 ml / day within the past 2 days which was not associated with pain, postural change, trauma or nose picking . He had a history of headache, that was dull aching in type and confined to the frontal re...
Since ancient times, prospective parents have tried to influence the sex of their future children . Aristotle, for example, advised those wanting a boy to have intercourse when the wind is in the north . Other people have assumed that special diets, the timing of intercourse in relation to ovulation, binding up one of ...
The accuracy of the measurement of the higgs - boson mass by the atlas and cms collaborations at the large hadron collider (lhc) has already reached the level of 300400 mev [1, 2] and, being still dominated by statistics, is bound to improve further when the lhc restarts operations in 2015 . This puts new emphasis on t...
Dynamic magnetic resonance imaging (mri) of the breast was reported to be a highly sensitive method for detection and further evaluation of clinically, mammographically, and sonographically occult cancers two different approaches are mentioned in literature aiming to improve the specificity: (1) single - breast imaging...
The past three decades of studies have unveiled some of the genetic underpinnings of human disease . For complex diseases, those with obscure genetic roots, discoveries have accelerated recently owing to a bloom of genome - wide association studies (gwass). Nevertheless, even for the most successful cases (such as infl...
The dominant role in muscle homeostasis and regeneration is played by satellite cells, which reside between the basal lamina and sarcolemma of myofibers . Satellite cells can be activated in response to both physiological stimuli, such as exercise, and under pathological conditions, such as injury and degenerative dise...
The quality of life is concerned with the degree to which a person enjoys the important possibilities of life. Oral health has a major impact on the general quality of life . People's oral health status can affect them physically and psychologically and influence how they enjoy life; how they look, speak, chew, taste, ...
Primary acquired nasolacrimal duct obstruction (pando) describes a condition of nasolacrimal duct obstruction caused by inflammation or idiopathic fibrosis.1 distal obstruction causes stagnation of lacrimal secretion, which may promote bacterial colonization and lacrimal sac infection . The clinical spectrum of nasolac...
Primary hepatic lymphoma (phl) refers to tumor confined in the liver at the early stage of lymphoma without infiltration of other locations . Phl is a rare disease, with an incidence of only 0.1% for malignant liver tumors . This disease also accounts for 0.4% of all primary extranodal lymphoma and 0.016% of all non - ...
Estimating the total species richness within large communities of species, using only samplings limited in sizes, is a common, long standing challenge which has elicited numerous procedures of estimations . For a few decades, a series of so - called nonparametricestimators provide elegant and convenient solutions to th...
Burrata is a traditional cheese produced in the apulia region (southern italy), particularly in bari, barletta - andria - trani and foggia provinces, as well as in martina franca, a town in the province of taranto . The product is a pasta filata (stretched curd) cheese consisting of a filling made of cream mixed with m...
Evidence for beneficial effects of solar ultraviolet - b (uvb) irradiance and vitamin d in reducing the risk of adverse health outcomes comes from a variety of study types: ecological, cross - sectional, case - control, cohort, and intervention . However, others have conducted systematic reviews that find the evidence ...
While brm scales with body mass (bm), several other factors seem to influence brm, such as sociability, environmental and dietary specializations, as well as energetic costs of brain tissue (mace et al ., 1981). Large brains contain more neurons and neural connections, and thus have greater potential for information pr...
Surface immobilization of poly(ethylene glycol) (peg), or pegylation, is widely used to modify nanoparticles (nps) with the goal to avoid undesired, nonspecific biological interactions . The covalent attachment of peg to nps results in the formation of a relatively inert hydrophilic corona that reduces uptake by the re...
A 55-year - old man who was a known case of scapular bone osteosarcoma, was referred to our clinic with ocular symptoms including acute painful decreased vision, proptosis, conjunctival injection, and chemosis . He had undergone surgical excision of the original tumor and received systemic chemotherapy 4 months before ...
Granulocytic sarcoma (gs), also known as chloroma, extramedullary myeloid tumor, myeloid sarcoma, leukocytic sarcoma and myelosarcoma is defined as an extramedullary tumor mass of immature cells of myeloid lineage [1 - 3]. Was reported by burn in 1811 . In 1853, king used the term chloroma, because of its greenish colo...
Diabetes mellitus (dm) is caused by genetic and environmental interactions, along with changing lifestyles and an aging population, increasing incidence of diabetes . Diabetic neuropathy is one of the major complications of diabetes with both type 1 and type 2 . Up to 50% of all diabetes have polyneuropathy which is a ...
The radiographic comparative analysis, in which antemortem and postmortem records are compared, is frequently used for personnel identification either in human remains or in living persons . Particular attention has been paid to the skull where several structures have the potential to identify an individual, including ...
Regional cerebral blood flow (rcbf) studies have been employed to investigate the pathophysiology of migraine headache [13]. The introduction of brain single - photon emission computed tomography (spect) using technetium tc 99m- (tc-) labelled hexamethylpropyleneamine oxime (hmpao) or ethyl cysteinate dimer (ecd) has f...
Histological studies have shown that the inferior alveolar nerve typically courses through the mandible as one major trunk with branches extending to apices of the teeth . However, there are multiple smaller branches of the inferior alveolar nerve (ian) running roughly parallel to the major trunk such bifid canals are ...
Loss of genome stability is an enabling hallmark of tumor progression, in which elevated rates of mutation and numerical / structural chromosomal aberrations combine to drive unrestrained cellular proliferation and resistance to cell death (hanahan and weinberg, 2011). Mechanisms that drive mutagenesis and copy - numbe...
The physical examination revealed no specific findings except for the scar from the transplant operation . His serum creatinine on presentation was 1.7 mg / dl and urine analysis showed adequate red blood cells . There were no abnormal findings in the bladder during cystoscopy and he underwent an abdominopelvic compute...
Inverted nipple may cause various cosmetic, psychological, breast feeding and hygienic problems . Providing a symmetrical nipple shape and position with permanent projection nonsurgical treatments include breast shells, breast pumps and syringe techniques . However, the beneficial and permanent effects of these treatme...
A 75 year old woman presented to the emergency room with a seven months history of increased fatigability, loss of appetite, weight loss and progressive abdominal distension . On examination the patient was markedly pale, asthenic, dehydrated and febrile and had altered mental status . Her general physical examination ...
This is a prospective, observational study approved by the institutional review board, and the study was conducted according to the tenets of the declaration of helsinki . Axial length (al) and anterior chamber depth (acd) were measured using an iolmaster (carl zeiss meditec, jena, germany). Central corneal thickness (...
The association of hepatitis b virus (hbv) and hematologic malignancies, including hodgkin lymphoma and non - hodgkin lymphoma (nhl) has been previously studied (1). Hepatitis b virus causes a wide range of liver diseases, including subclinical infection, acute, chronic and fulminant hepatitis . Chronic hbv may lead to...
While ecstasy is a drug used for fun today, it has serious side effects and sometimes it can be fatal . These effects are due to idiosyncratic reactions as a result of various stimulations in adrenergic receptors . Short after it is swallowed, it causes sweating, tachycardia, tiredness, muscle spasms, and jaw locking; ...
Increased industrialization is posing a threat to human health in the form of environmental pollution . Environmental remediation of organic pollutants by photocatalytic degradation using wide bandgap semiconductors has attracted considerable attention in recent times.14 further, these materials, in a nanostructured fo...
Partial duplication of intracranial arteries, so called fenestration, is known to have an angiographical incidence of 0.3 to 0.9%, and is frequently associated with aneurysms22). Fenestrated arteries are often observed in the posterior circulation, but are known to be relatively unusual in the anterior circulation19). ...
Left ventricular noncompaction has been classified as a primary cardiomyopathy with a genetic origin.1 morphologically, this condition is characterized by a thickened, two - layered myocardium with numerous and prominent trabeculations and deep, intertrabecular recesses.13 left ventricular noncompaction may be an isola...
Coronary artery bypass grafting (cabg) with cardiac vale repair is an uncommon surgery in infants . Cabg is technically demanding in infants due to the small size not only of the coronary arteries but also the potential graft arteries . The short and long - term outcome of surgery is not known and thus has largely been...
Developmental variations and morphological abnormalities such as cervical enamel projections, enamel pearls, and palatogingival grooves contribute to localized periodontal disease progression . The major variant of this tooth type is the presence of an additional third root or a supernumerary lingual root called radix ...
The burnout syndrome is a serious consequence of chronic exposure to work - related stressors . The construct of burnout syndrome appeared for the first time around the early 1970s, aimed at explaining the process of physical and mental deterioration in professionals working in areas such as teaching, health care, soci...
Patients with a first episode of graves' hyperthyroidism (gh) are often treated initially with pharmacological therapy . Many clinicians use a therapeutic regimen commonly referred to as block and replacement therapy this involves the administration of a thyroid - hormone- (th-) synthesis - blocking agent such as methi...