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During the past three decades, the life expectancy for individuals with hemophilia a (a hereditary deficiency of coagulation factor viii) and hemophilia b (a hereditary deficiency of coagulation factor ix) has markedly increased, primarily due to advances in medical care, as well as the introduction and availability of... |
Patient 1 was a 52-year - old woman with a history of hypertension who became ill on may 1, 2014, and was admitted to hospital a on may 11 with high fever (temperature> 38c), cough, dyspnea, diarrhea, and anorexia . Her condition deteriorated, and she was transferred to an intensive care unit (icu). Her condition remai... |
A central aim of untargeted metabolomics and metabonomics studies is the identification of marker metabolites which play a crucial role in the experimental context [1, 2]. Mass spectrometry combined with either gas chromatography (gc / ms) or liquid chromatography (lc / ms) has become a key technology for metabolome an... |
Women differ from men in coronary artery disease epidemiology, symptoms, pathophysiology, and clinical outcome [13]. Several studies have reported that women are associated with an increased mortality rate following coronary interventions compared with men . The worse outcomes in women might be partly explained by some... |
Following approval by our institutional review board, the medical charts of patients who received stsg for treatment of foot and leg ulcers between 2002 and 2010 were identified and retrospectively reviewed . Inclusion criteria included those patients who had a documented history of diabetes mellitus and an ulceration ... |
Phospholipids containing polyunsaturated fatty acids are highly prone to modification by reactive oxygen species, thereby generating a plethora of biologically active oxidized phospholipids (oxpls). A variety of (patho-) physiological effects ascribed to oxpls underline their relevance, e.g., in inflammation, atheroscl... |
Ilio - iliac arteriovenous fistula (avf) is a rare disease that occurs in less than 1% of all common iliac artery aneurysms (ciaas) and in 27% of ruptured aneurysms . Surgical repair of an avf resulting from a ruptured abdominal aortic aneurysm (aaa) was first described by cooley in 1955, and several similar cases have... |
Percutaneous coronary intervention (pci) has become the first - line treatment for patients suffering from obstructive coronary artery disease (cad). Drug - eluting stents (des) have significantly reduced the risk of restenosis and the need for repeat revascularization when compared to bare metal stent (bms).1 in the r... |
The reconstruction of multiple missing teeth with dental implants is a predictable and proven treatment technique for edentulous patients in both anterior and posterior regions.12 however, the molar teeth are often shown to be a troublesome area for implant restorations from mechanical and biological aspects,3 which is... |
Worldwide, approximately 1.38 million women are diagnosed with breast cancer each year . In developed countries, 80% of women with breast cancer will survive at least 60 months due to early detection techniques and effective anti - cancer treatments . In the uk, there are currently around 550,000 breast cancer survivor... |
Toll - like receptors (tlrs) are a family of transmembrane receptors which play an important role in the host defense against microorganisms . Tlrs are mainly expressed in human immune - related cells such as monocytes, neutrophils, macrophages, dendritic cells, t cells, b cells and nk cells . They initiate inflammator... |
Rhegmatogenous retinal detachment (rd) is caused by liquefied vitreous passing through a retinal break into the subretinal space, separating the neurosensory retina from the retinal pigment epithelium . Low myopes [0.75 to 2.75 diopters (dpt)] show an odds ratio of 3.14 for rd, and the odds ratio was shown to rise stee... |
We report an unusual case of bilateral vertical lacquer crack with no history of ocular trauma and with progressive marked enlargement and consequent visual loss . Three - year follow - up was completed using best - corrected visual acuity, serial fundus photographs, intravenous fluorescein angiography, and optical coh... |
To estimate the effect of the dioxin crisis on the number of campylobacter infections, a model was designed by which the number of expected cases for 1999 could be calculated . This model was based on the data collected by the sentinel laboratory surveillance network from 1994 to 1998 . The cumulative numbers per week ... |
Pain in the region of the pes anserinus (pa) insertion is a common rheumatologic condition diagnosed as pes anserinus tendinitis or bursitis (patb) syndrome . Its diagnosis is entirely based on clinical manifestations, which is marked by spontaneous medial knee pain on climbing or descending stairs, tenderness at the p... |
The expression of the disease results from the interaction of host defense mechanisms, microbial agents, environmental, and genetic factors . Various compounds, such as cytokines, have been detected in gingival crevicular fluid (gcf) and may be especially beneficial for diagnosing current periodontal status and address... |
Biomethylation of metals and metalloids by microorganisms is a widespread phenomenon in anaerobic habitats including waste deposits, sewage sludge, and alluvial soils [13]. The stepwise methylation results in both partly methylated nonvolatile species as well as fully methylated volatile metal(loid) compounds . Conside... |
A 56-year - old hispanic male presented to the emergency department for gradually progressive shortness of breath and chest tightness of 4-hour duration . He was recently diagnosed with stage iv mantle cell lymphoma and had received his first cycle of r - chop (rituximab, cyclophosphamide, doxorubicin, hydrochloride (h... |
The global incidence of malignant diseases has significantly increased during the last decades in parallel with the rapid industrialization of most countries . In iran, as the third cause of death and the second prevalent chronic diseases, cancers pose a significant health burden . Malignancies are considered primarily... |
The dr - tb stat task force comprises stakeholders working to introduce new medications for treating mdr tb (table 3). Dr - tb stat officially became a task force of the gdi in july 2015 . Although task force status was pending, dr - tb stat held its initial meeting in april 2015, and since then has met monthly by conf... |
A couple s intentions to have a number of descendants can be thwarted in a number of ways . The most difficult of factors are those that are restrictive and outside of a couple s sphere of influence or resources . The need to have a child can be reflected in motives such as happiness, well - being (family relationships... |
Acute heart failure (ahf) is associated with an adverse prognosis with an all cause mortality (acm) of 1020% at 23 months and 1737% at 1 year.1, 2, 3, 4, 5 single biomarkers on top of clinical assessment are useful for risk stratification in patients with chronic heart failure (hf).6, 7 however in ahf, the incremental ... |
Native hawaiians are descendents of the aboriginal peoples inhabiting the hawaiian archipelago prior to western contact in 1778 and exercising sovereign governance prior to the 1892 overthrown of the hawaiian kingdom by the united states (usa) [1, 2]. The 2000 us census enumerated 401,000 americans (0.1% of the total p... |
Insomnia is the most common sleep disorder, characterized by difficulty in falling asleep and/or maintaining sleep . It can also lead to emotional consequences, which further lead to affective disorders, such as, depression and anxiety . The prevalence of insomnia in the general population, by strictly applying the dia... |
The etiology was presumed to be tubercular if there was (a) corroborative evidence (such as a positive tuberculin skin test or quantiferon - tb gold test), (b) exclusion of all other known causes of infectious uveitis except tuberculosis and noninfectious uveitic syndromes, and (c) a favorable therapeutic response to a... |
Lipopolysaccharide (lps) is a major component of the cell wall of gram - negative bacteria and is a well - known potent inducer of inflammation and inflammatory bone loss [15]. Lps is known to induce the production of many local factors, including proinflammatory cytokines, such as tnf- and il-1, from macrophages or ot... |
Ambulatory peritoneal dialysis is the preferred form of dialysis in countries where the facility of maintenance hemodialysis is limited . Infections in the form of peritonitis, exit site infections and tunnel infections are the most common problems with peritoneal dialysis . Although gram - positive bacilli are the mos... |
Hepatitis b virus (hbv) and hepatitis c virus (hcv) infections are still among the important health issues, in turkey . However, human immunodeficiency virus (hiv) infections are less frequently observed, in the country . Although the modes of transmission are through parenteral, horizontal and vertical routes, while i... |
Traditional culture techniques and the use of agar plates remain important tools in the identification of bacterial infections and are still in common use within the field of diagnostic microbiology . In other areas of the clinical laboratory, a combination of diagnostically effective screening tests and automation has... |
While the past 20 or 30 years of development in chemoinformatics has created a plethora of published software systems and algorithms for solving chemical problems, little effort has been spent in providing the community with open components and data, to be reused and improved by communal efforts . Bioinformatics, with ... |
Neonatal chronic lung disease (cld) (1 - 3) is one of the serious sequelae of very low birth weight infants . Inspite of various therapies such as fluid restriction (4), corticosteroids (5), vitamin a (6), low positive inspiratory pressure (pip) and permissive hypercapnea (7), high - frequency ventilation (hfv) (8) and... |
The aryl hydrocarbon receptor (ahr) is an evolutionarily ancient protein, which first appeared within the vertebrate class 450 million years ago . Although historically most frequently studied in the context of regulating responsiveness to environmental toxicants, both the existence of ahr prior to industrialization an... |
F. mangiferae isolated from malformed floral tissues of dashehri cultivar of mango demonstrated light purple in addition white colony color . Microscopic study f. mangiferae revealed the presence of micro- and macro - conidia, however chlamydospores were entirely absent . Both the micro- and macro - conidia may germina... |
The online version of this article (doi:10.1007/s13555 - 016 - 0093-x) contains supplementary material, which is available to authorized users . Onychomycosis is a common infectious disease, which if inappropriately treated can lead to spread of the infection, complications, diminished patient quality of life and may r... |
After the introduction of the laminoplasty by hirabayashi in 19779), the expansive open door laminoplasty has become a widely adopted surgical procedure for treating multilevel cervical spondylotic myelopathy (csm), ossification of posterior longitudinal ligament (opll), spinal cord injury without fracture and dislocat... |
Hydrogen peroxide is a chemical compound that has a single peroxide chain which is unstable and splits into reactive radicals . In the past it was used for therapeutic enemas to relieve meconium ileus in infants and fecal impaction in adults for nearly 100 years, but this practice has largely been abandoned after it wa... |
Intraductal papillary neoplasms of the breast form a wide spectrum of pathological changes, with benign intraductal papilloma on one end of the spectrum and papillary carcinoma at the other end . Intracystic papillary carcinoma (ipc) is a variant of papillary carcinoma and accounts for 0.5 - 1% of breast cancers [2 - 4... |
The recent development of a radioreceptor assay for thyrotrophin has made it possible to detect immunoglobulins that inhibit the binding of thyrotropin to its receptor in some patients with autoimmune thyroid diseases . Although these immunoglobulins have been detected primarily in patients with graves disease, in whom... |
Ms incidence has increased, particularly among females [14], indicating the influence of environmental factors . The integration of magnetic resonance imaging (mri) in diagnostic criteria since the 1990s and progress in immunomodulatory drug treatments have contributed to these increasing rates [5, 6]. Studies performe... |
Distal median nerve masses may be developed post - traumatic or non - traumatic . In this paper, we aim to present a 52 year old female case with a postraumatic neuroma of the median nerve in the left wrist . A 52-year - old female patient had accidental incised wound over her left wrist which was primarily sutured . I... |
While pancreatic resection is the only effective treatment with prolonged survival in operable pancreatic cancer and peri - ampullary cancer, it is also a procedure of significant morbidity and complications . The most commonly reported postoperative complications after pancreatic resection are pancreatic fistula, dela... |
The natural history of idiopathic pulmonary fibrosis (ipf) is characterized by decreasing pulmonary function over time . Some patients may experience acute exacerbations (ae)sudden worsening of pulmonary function, increased oxygen requirements, new opacities on chest imaging, and a diffuse alveolar damage (dad) pattern... |
Pharmacies assume an imperative part in the provision of health care and well - being at the community level . Generally, pharmacies have extended working hours, are commonly visited, and conveniently placed within the heart of community dwellings . The pharmacist's contribution is significant in health promotion, heal... |
Molar pregnancies represent a significant burden of disease on the spectrum of gestational trophoblastic diseases . The incidence appears to be higher in women from south asia, including a trend towards recurrent molar pregnancies [1, 2]. This higher trend in some populations has been attributed to nutritional and soci... |
Pentacene was deposited on a muscovite mica surface by physical vapor deposition from a knudsen cell in an ultrahigh vacuum chamber . The cell temperatures were adjusted between 450 and 490 k, in order to realize deposition rates between 0.01 ml / min and 4.5 ml / min, respectively . The mica samples (10 10 0.01 mm) we... |
Moyamoya disease (mmd) is characterized by a chronic progressive steno - occlusive change of the distal internal carotid artery and abnormal development of a fine vascular network (moyamoya vessels) at the base of the brain . Takeuchi and shimizu11) had initially reported this disease in 1957, followed by suzuki11) in ... |
The question which diagnostic test should be used in case of abnormal uterine bleeding is still a matter of debate . Diagnostic algorithms for intrauterine disease are usually based on studies and meta - analyses published in the literature and mostly include one or more of the following diagnostic modalities: office e... |
This randomized, examinerblind, paralleldesign, controlled, singlecentre study was conducted in the usa between 1 november and 2 december 2011 . The primary objective was to compare the efficacy in reducing gingivitis and plaque of an experimental mouthrinse containing 0.15% lae with that of a mouthrinse containing 5% ... |
Human herpes virus 4 (hhv-4), also called epstein - barr virus (ebv), as a member of herpesviridae, is one of the most common viruses in humans . It is commonly associated with non - specific clinical signs and is usually presented by painful sore throat, swollen glands, chills, fever and chronic fatigue syndrome . The... |
Mongolia has the highest incidence of hepatocellular carcinoma (hcc) and liver cirrhosis (lc) worldwide (fig . Hcc occurs in 61.9 patients per 100,000 population each year, and lc occurs in 350 patients per 100,000, and its high occurrence has been attributed to the high prevalence of chronic viral hepatitis . The hepa... |
Physical stimuli can significantly alter cellular behavior, giving rise to biochemical signals involved in molecular response.1 this process is called mechanotransduction, and the responsible structures sensitive to mechanical forces are most probably cytoskeleton elements.2 a number of studies have demonstrated that c... |
Subarachnoid hemorrhage (sah) is one of the most common radiological features of traumatic brain injury (tbi) occurring in 30%40% of moderate severe head injuries . Vasospasm and resulting cerebral ischemia as well as cerebral hyperemia can cause delayed neurological recovery and poor outcome . A 56-year - old male suf... |
Angiolipoma (al) is a relatively rare tumor of the head and neck region, although it occurs more commonly in the forearm and the trunk regions . This tumor has been rarely reported in the oral cavity, and to best of our knowledge, it has only been reported twice in the lip . The histological characteristics of angiolip... |
Superior semicircular canal dehiscence syndrome (scds) is a recently recognized clinical condition, which was initially described by minor, et al.1) the syndrome usually encompasses a constellation of vestibular and audiological symptoms, such as sound and/or pressure induced vertigo and oscillopsia, along with conduct... |
The malaria parasite, plasmodium, is a major public health burden in the developing world, and despite the existence of antimalarial treatment active in blood stages of infection, there is a continual need for novel drug design as the parasite develops resistance to current treatments . Additionally, treatment for the ... |
This retrospective study included patients who had undergone ct between january 1, 2010, and december 31, 2010, and met the following criteria: they were over the age of 20 years, they gave us their informed consent and they underwent ct examinations to assess abdominal or urological lesions for reasons unrelated to lb... |
Kawasaki disease (kd) is an acute multisystem vasculitis that afflicts mostly young children . Since the first report of kd in 1967 (1) however, the clinical and epidemiologic studies have proposed that kd is closely related to an infectious disease (2, 3). The acute onset of a self - limited course, the prevalent popu... |
Advances in adjuvant and neoadjuvant therapies and accurate preoperative imaging techniques have improved the prognosis of patients with sarcoma . Tumors in the diaphysis are relatively uncommon, and in some patients it may be possible to achieve adequate margins without sacrificing the adjacent articular surface . Ava... |
Diabetes mellitus is a chronic metabolic disorder that can result in multiple long - term micro- and macrovascular complications . Diabetes is well known as the leading cause of blindness, end - stage renal disease (esrd) and limb amputation . In korea, approximately 18.6% of diabetic patients have retinopathy, 27.3% a... |
Retinitis pigmentosa (rp) is the term used for a group of retinal diseases that are characterized by inherited, progressive degeneration of retinal tissue, mainly rod and secondarily cone photoreceptors . The clinical features are night blindness and visual field (vf) loss due to loss of rod photo - receptors . Many pa... |
Alzheimer's disease (ad) is the most common form of dementia in the elderly . It is characterized by neuronal cell loss and progressive accumulation of neurofibrillary tangles (nft) in neurons, and amyloid fibers in neuritic (senile) plaques and in the walls of blood vessels . As the disease progresses, ad patients exp... |
Hsp can affect multiple organs presenting with a characteristic rash in most of the patients . Familial mediterranean fever (fmf) is an inherited inflammatory disease common in mediterranean populations . A 16 year old boy was referred with history of abdominal pain lasting for 20 days . He was hospitalized and had app... |
Periodontal plastic surgery procedures address these esthetic and functional demands and have become an integral part of the periodontal treatment . Several therapeutic modalities such as free gingival autografts, pedicle grafts, connective tissue graft, grafts combining the two modalities, and guided tissue regenerati... |
Myasthenia gravis (mg), an autoimmune disease, impedes the postsynaptic acetylcholine receptors at the neuromuscular junction.1 ocular mg is a representative manifestation of this entity in which blepharoptosis and/or eye movement disturbances are often encountered.2 in general, up to 85% of all myasthenic patients sho... |
Polycystic ovary syndrome (pcos) is a common endocrine problem, which is now recognized as not only a reproductive but also a metabolic disorder with long - term effects on women's health . Pcos is associated with hyperinsulinemia which is associated with infertility and metabolic problems of diabetes and dyslipidemia ... |
Chronic low back pain is well known as a public health epidemic . In highly developed countries, it is one of the top three causes of degradation in quality - adjusted life - years, along with ischemic heart disease and chronic obstructive pulmonary disease.1 while lumbar spine pathology is an important cause of chroni... |
The diet and lifestyle questionnaire of vip, including a semi - quantitative food frequency questionnaire (ffq), has been completed by almost all participants, with an average recruitment rate for period included in this study (19902008) of 59% within the target age - groups . In support of the population - based natur... |
Metachromatic leukodystrophy (mld) (scholz's disease) is an autosomal recessive lysosomal storage disease caused by the lack of arylsulfatase a (asa). This enzyme is essential for the normal metabolism of sulfatides which are vital elements of the myelin sheath . In mld, sulfatides accrue in many organs comprising brai... |
Patients' active participation in their own care is known to increase motivation and adherence to prescriptions, give better treatment results, create greater satisfaction with received care, and reduce stress and anxiety . Patient participation is an important basis for nursing care and medical treatment and it is als... |
Triamcinolone acetonide (ta) injections are often used to treat tendinopathy, but it has substantial adverse effects, such as impaired function of supraspinatus tendon cells and high rate of re - rupture . Previous studies also reported the deleterious effects of ta on histological and biomechanical properties of the i... |
The development of cancer is a complex multistep process that requires the accumulation of mutations resulting in a cell acquiring the essential hallmarks of cancer: evasion of apoptosis, self - sufficiency in growth signals, insensitivity to antigrowth signals, invasive and metastatic abilities, limitless replicative ... |
Are currently classified as overweight or obese (bmi 25 kg / m), and one - third of them are frankly obese (bmi 30 kg / m) (1). Is 26.1 million in 20052010 or 12% of the population (2). Among u.s . Diabetic patients, the prevalence of overweight or obesity has increased to 80% (3). Obesity is associated with increased ... |
Xanthomatous infiltration may be a risk to the rotator cuff muscles and long head of the biceps . We believe it is a rare entity where there is fatty infiltration of the shoulder tendons, predisposing the shoulder to rotator cuff tear . It may be diagnosed on mri, in patients with hyperlipedemia . We describe the mri f... |
Contingent valuation (cv) is a survey - based hypothetical and direct method to estimate monetary valuations of effects of health technologies . The validity of cv to elicit monetary valuations of health care provisions has been adequately established in the literature [2 - 6]. There have been several attempts to use t... |
To report a case of radiation - induced macular ischemia where vision and macular perfusion improved after hyperbaric oxygen (hbo) therapy . A 62-year - old male patient developed radiation - induced macular ischemia after he was treated with radiation for brain glioma . The patient presented with best spectacle - corr... |
Diabetes mellitus has long been considered a disease of carbohydrate metabolism, and before the discovery of insulin in 1921, low carbohydrate starvation diets were the default treatment . From the 1930s through to the 1960s, many experts continued to advise strict carbohydrate restriction, with the result that most pe... |
The prevalence of overweight and obesity has increased over the last decade, and current measures have not been able to stem the tide . A wide variety of weight management strategies are presently available, and some involve the use of dietary supplements marketed as slimming aids . Hca is a derivative of citric acid a... |
The tumor was named aggressive due to its characteristically slow and insidious growth as well as carrying a moderate - to - high risk of local relapse . Usually, it presents as a vulval polyp clinically and is diagnosed only on histopathology . It is a rare local mesenchymal tumor of unknown etiology usually affecting... |
Chronic autoimmune hepatitis (cah) is a serious hepatic disease with an immunological attack against the liver cells . Autoimmune diseases result from immune response toward healthy tissue; hence, they can have protean manifestation with multi - system involvement . Central pontine myelinolysis (cpm) is an uncommon con... |
A pregnant 23-year - old female with a six - year history of type 1 diabetes presented with a complaint of increased blur in both eyes for the previous two months . Best corrected visual acuity was 20/40 ou . Slit - lamp examination was entirely unremarkable in both eyes . Dilated funduscopic examination was significan... |
We report choroidal findings by means of enhanced depth imaging spectral - domain optical coherence tomography (edi - oct) in a patient with idiopathic uveal effusion syndrome (iues). A 41-year - old man was referred to us with ciliochoroidal and non - rhegmatogenous retinal detachments . Sclerectomies and sclerostomie... |
Dna topoisomerasesregulate the topological state of dna as required to relieve superhelical density for important biological processes such as replication and transcription [13]. Dna topoisomerase 1 (top1) is expressed at elevated levels during s - phase of the cell cycle and is the topoisomerase primarily responsible ... |
Leptospirosis commonly presents as an acute illness occurring in a biphasic pattern of fever followed by an afebrile period and again fever with organ involvement . Neurological involvement (neuroleptospirosis) is rare . Among the several manifestations of neural involvement, myeloradiculopathy, myelopathy, cerebellar ... |
Mood disorders are disturbances in a person s mood categorized into major depressive disorder (mdd) and bipolar disorder (bd). Mdd and bd appear to be the most important risk factors for lifetime suicide in any psychiatric disorder.1 it has been estimated that at the time of suicide, 87.3%98% of psychiatric disorders a... |
Tears in the retinal pigment epithelium (rpe) occur spontaneously in the course of exudative age - related macular degeneration (amd). Rpe tears also occur following photodynamic therapy (pdt) and laser therapy, and are observed in polypoidal choroidal vasculopathy (pcv) [35]. Eyes with occult exudative amd and retinal... |
The study site was a deer farm with 900 hinds, including 550 adult hinds and 350 yearling hinds . This farm is located in the los alcornocales natural park in the cdiz province (andaluca, southern spain; 3617n, 547w), an area near the sea that is <500 m above sea level . Abundant wild red deer and moderate densities of... |
It includes nonoperative management with traction followed by immobilization in halo vest or somi brace or operative management in the form of posterior fixation with c2 pedicle screw only or c2-c3 fusion with c2 pedicle and c3 lateral mass screw and c2-c3 anterior fusion . However, when untreated it poses a complicate... |
Idiopathic gingival fibromatosis (igf) is an uncommon, benign, hereditary, slowly progressive, nonhemorrhagic fibrous enlargement of keratinized gingiva . It usually begins at the time of eruption of permanent teeth, but can develop with the eruption of deciduous dentition and rarely present at birth . The hyperplastic... |
Male fvb / n jcl mice (clea japan, tokyo, japan) were studied at 1216 weeks of age . The animals were housed individually in plastic cages at 24 1c with lights on from 0600 to 1800 h, and they were maintained with free access to a laboratory diet (oriental yeast, tokyo, japan) and water . Mice were anesthetized by intr... |
The street foods play an important socioeconomic role in meeting food and nutritional requirements of city consumers at affordable prices to the lower and middle income groups and are appreciated for their unique flavors and convenience [13]. Street foods also assure food security for low income urban population and li... |
After institutional review board approval, we did a retrospective chart review of infants 1500 g birth weight and treated for aprop between january 2006 and december 2009 . The neonatal intensive care unit at our institute is a level iii nursery, which also caters infants born at other centers (outborn). Aprop was diag... |
Generally speaking, cell transplantation studies anticipate that transplanted cells survive long - term to be integrated into the host spinal cord tissue, serving as a scaffold for the outgrowth of regenerating axons in spinal cord injury . . However, this anticipation is not necessarily applicable to some somatic cell... |
Primary adhesive capsulitis is a common shoulder condition characterized by painful loss of both active and passive range - of - motion in all planes of the glenohumeral joint, especially external rotation . Although the pathogenesis progresses through fibrosis and culminates in joint contracture, it is generally recog... |
The treatment of chronic inflammatory bowel disease (ibd) is always a challenge for gastroenterologists dealing with this type of condition.1,2 indeed, the variability and complexity of the clinical picture, the possibility that other organs and systems may be involved, and the possible toxicity caused by drugs make bo... |
A recent study demonstrated that a pest - like sequence present at the nh2 terminus of llo and absent in pfo is responsible for the rapid degradation of llo in the host cell cytosol (decatur and portnoy, 2000). Pest - like sequences are thought to target eukaryotic proteins for phosphorylation and degradation, and dele... |
X - linked severe combined immunodeficiency (x - scid) is a rare, life - threatening disease that is characterized by marked impairment of both cellular and humoral immunity (1). Human x - scid occurs in as many as 50% of patients with primary scid; patients have complete or marked deficiency of t cells but carry a nor... |
This study was a cross - sectional study of penicillin susceptibility among clinical blood isolates reported at all acute - care hospitals in the delaware valley case control network (dvccn). Dvccn is a population - based network of all adult acute - care hospitals in the five pennsylvania counties around the metropoli... |
It is essencial to localize the toxic region accurately in hyperthyroid patients before making a decision to remove with operation . Here we report a cese of an intrathoracic toxic thyroid nodule causing hyperthyroidism with a multinodular normal functional cervical thyroid gland . A 62-year - old female presented with... |
More than 2 billion people globally are estimated to suffer from micronutrient deficiencies (von grebmer et al . Iron, zinc, vitamin a, iodine, folate and other vitamin b deficiencies are among the most widespread global micronutrient deficiencies (muthayya et al . Factors that contribute to poor micronutrient intake a... |
Cysticercosis, caused by the metacestode stage of taenia solium, is a serious health and veterinary problem in many developing countries [13]. In humans, t. solium cysticerci cause neurocysticercosis, which affects ~50 million people worldwide, and t. solium also infects pigs, its intermediate host, leading to major ec... |
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