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A class of small rnas, piwi - interacting rnas (pirnas), is associated with the piwi clade of argonautes and acts to repress mobile genetic elements in the germline of both drosophila and mammals (fig . 1, left side). Pirnas are generated by rna - transcription of long te clusters, resulting in the accumulation of shor... |
Encouragingly, the boolean model was able to make highly accurate predictions on spatial and temporal gene expression patterns . Indeed, only several predictions among the 2,772 time - space - gene combinations were at odds with experimental data . This may not seem surprising because the grn is based on interpretation... |
According to the international diabetes federation in 2013, 328 million people are currently diagnosed with diabetes and there is a projected rise of 55% to 592 million people in the world living with diabetes by the year 2035.1 the greatest rise is projected to occur in africa, the middle east, southeast asia, and sou... |
Influenza a virus infections in birds account for important inputs into the evolutionary porcine - human complex of this prominent anthropozoonotic pathogen . Among influenza a viruses, which broadly exhibit 17 ha and 9 na antigenic subtypes, only three haemagglutinin (ha) subtypes (h1, h2, and h3) and two neuraminidas... |
There are changes for mortality, communicable diseases (cd), and non communicable diseases (ncd) worldwide (16). Sub - saharan africa shows several studies about poverty, industrialization, urbanization, and epidemiologic transition (614). In particular, significant changes in the delivery of health care in the public ... |
, multisensory processing has been an active topic of research and numerous studies have demonstrated that multisensory processing can improve accuracy (e.g., sumby and pollack, 1954, reduce reaction times, e.g., gingras et al ., 2009), improve precision (e.g., ernst and banks, 2002; alais and burr, 2004), and provide ... |
Charcot marie tooth disease (cmt) is a clinically and genetically heterogeneous group of sensorimotor peripheral neuropathies and represents the most frequent inherited disorder(s) affecting the nervous system . In this study, we provide preclinical, proof of principle data demonstrating efficacy in a mouse model of th... |
Measuring performance of health systems is an essential tool for health policy - makers to conduct analysis and track change . The 2000world health organization (who) report reflects that promoting health status, fairness in financing and responsiveness are the three main goals of evaluating health system performances ... |
The large number of photoswitchable biomolecules discovered and developed in recent years covers a great variety of cellular functions, like catalysis of metabolic processes, cytoskeletal polymerization and motors, nucleic acids dynamics, intracellular signaling, and, perhaps most dazzling, membrane excitability, which... |
Cyclophosphamide is nitrogen mustard - derived alkylating agent used as a cytostatic drug in the treatment of lymphomas, some forms of leukemia, and some solid tumors . Symptoms of neurotoxicity are common in myeloablative regimens of the therapy with nitrogen mustard - derived alkylating agents used as cytostatic drug... |
Acute obstructive suppurative pancreatic ductitis (aospd) is a rare complication of chronic pancreatitis that has been described in only seven previous case reports since 1995 . Aospd is defined as suppuration from the pancreatic duct; however, in contrast to the pancreatic infections that typically complicate chronic ... |
The definition of a gerbode defect, according to the society of thoracic surgeons congenital heart nomenclature and database project is true left ventricular (lv) to right atrial (ra) communication . However, no sources provide a definition encompassing congenital right ventricular (rv) to left atrial (la) communicatio... |
Water intoxication is a fatal disorder with brain function impairment, defined as hypo - osmolar syndrome resulting from an excess intake of water, with dilutional hyponatremia formed principally by (1) the retention of water exceeding renal free water excretion, or (2) impaired free water excretion from the kidneys . ... |
Unexpandable lung is a mechanical complication resulting in the inability of the lung to expand to the chest wall . In clinical practice, an unexpandable lung may be due to either the presence of pleural disease, endobronchial obstruction resulting in lobar collapse, or chronic atelectasis . Unexpandable lung due to pl... |
The serum samples were collected as part of a household survey conducted during 20132014 in 2 eastern counties of kenya, garissa and tana river (technical appendix). Of those for whom information about sex and age was known, 603 were female and 407 were male, and median age was 27 (range 590) years . Occupational data ... |
Granular cell tumor (gct) is an uncommon condition of the skin that was described firstly by weber in 1854 and established as a clinical entity by abrikossoff in 1926 who termed it as granular cell myoblastoma . The tumor occurs frequently among women and blacks, between the second and sixth decades of life . The commo... |
The juice was extracted from the fruits and subjected to centrifuge . In the supernatant equal amount of ethanol was added and kept it in refrigerator for 30 min, then centrifuge the mixture and dry at room temp . Fine powder was collected as bio - polymer . For the granulation 1%, 3% and 5% solution of polymer was mad... |
Normal c57bl/6 mice and mice containing foxo1 knock - in (foxo1tag), foxp3-ires - rfp and bira alleles or foxp3-ires - rfp and bira alleles were previously described . Treg cells in mice carrying the foxp3-ires - rfp allele were marked by red fluorescence protein (rfp). All mice were maintained under specific pathogen ... |
Programmed cell death (pcd) plays an important role in sculpting tissues during animal development (adams and cory, 2002; danial and korsmeyer, 2004). The molecular regulators that are central to this process seem to be evolutionarily conserved from worms to mammals (danial and korsmeyer, 2004; horvitz, 1999) and inclu... |
Its effect is mediated via interactions with several receptors in the central nervous system and results from a combination of antidopaminergic, anticholinergic, antihistaminic, and weak antiadrenergic actions . The therapeutic effects of chlorpromazine are frequently accompanied by unwanted side effects that include s... |
Multiple sclerosis (ms) is a chronic inflammatory disease of the central nervous system (cns) that results in impairment of a range of functions, including physical disability and cognitive dysfunction (krupp et al ., 1989; magnetic resonance imaging (mri) of the brain is an established tool to monitor disease activity... |
It affects most organ systems including skin, heart and blood vessels, bone, nervous system, and eye [1, 2]. The ocular manifestations of acquired syphilis are protean and syphilitic uveitis may be included in the differential diagnosis of any form of ocular inflammation . A classic treatment regimen for neurosyphilis ... |
In vivo, the biologically active form of dna in prokaryotes is negatively supercoiled . The amount of superhelical stress imposed on the dna is determined by the levels of competing dna topoisomerase enzyme activities, and by local events such as protein binding or dna transcription (13). Transient changes in the level... |
The importance of parasites in shaping community structure and influencing ecosystem functioning in the marine environment has gained considerable recognition over the past few decades (dobson and hudson, 1986, poulin, 1999, poulin et al ., 2016). Parasites have complex roles in community ecology by influencing populat... |
Clustering of several risk factors for cardiovascular disease, obesity (particularly abdominal obesity), dyslipidemia, insulin resistance, and hypertension . Obesity is a public health concern because of its association with a number of medical complications that lead to increased morbidity and mortality . The most com... |
Approximately, two - thirds of all gists occur in the stomach, followed by the small intestine, rectum, and esophagus . Moreover, the body and fundus are the most frequent site of gists in stomach . Endoscopy reveals a smooth mass with normal overlying mucosa or with mucosal ulceration in larger tumors . Tissue samplin... |
A 53-year - old caucasian female with complaints of dry eyes and a burning sensation in the eyes presented to our ophthalmology clinic 5 years ago . Her medical history revealed that the symptoms had persisted for 10 years, with some relief with lubricating eye drops used every 0.51 h. prior serology studies for antinu... |
Atherosclerosis is a common disease primarily affecting large arteries, which begins in childhood and progresses with age . It is the principal cause of heart attack, stroke, and gangrene of the extremities . Several pathophysiologic mechanisms, including the inflammatory response, immune response, cellular growth and ... |
In february 2012, the birmingham and solihull tb service noted 2 distinct 24-loci miru - vntr strain types of mycobacterium tuberculosis (clusters a and b) isolated from 4 eritrea - born patients with pulmonary tb . The diagnoses were made in july (cluster a) and december 2011 (cluster b). Epidemiologic links were cons... |
Abdominal wall pain is a common complaint, and patients can present with it in the acute perioperative period as well as in a chronic pain state.1 pain - relieving therapies are varied, and range from oral medication to interventional procedures . Recently, the ultrasound - guided transversus abdominis plane (tap) bloc... |
Unless otherwise stated, all chemicals and solvents were purchased from commercial suppliers in reagent- or technical - grade quality and used directly as received without further purification . The bis(arylimino)acenaphthene ligands were prepared from acenaphthenequinone and the corresponding substituted anilines in a... |
Solar lentigines are well - circumscribed or irregularly shaped dark brown or black macules that occur on sun - exposed areas, predominantly on dorsal aspects of the hands and the face . Because of the negative social impact on quality of life, there are two types of treatment: (1) physical therapies, which include cry... |
Cardiovascular disease (cvd) is a major cause of death and an important contributor to the wide and growing inequalities in mortality in high - income countries.1 as a result, the reduction of cvd has long been an objective of health policy in the uk and elsewhere, with a series of initiatives introduced with this as e... |
Providing immigrants with proper health care is a challenge, given language barriers and cultural differences . At the primary health care level, it becomes the responsibility of the clinic to arrange such practical issues as providing capable interpreters when needed . One of the fundamental objectives of public healt... |
Twenty - two volunteers (10 women) aged between 18 and 50 years underwent a rigorous protocol using standard measures of obesity and insulin resistance . Specifically, participants were nondiabetic (normal glucose tolerance or impaired glucose tolerance) according to an oral glucose tolerance test (ogtt) (world health ... |
Mankind is still struggling against the parasites, plasmodium is considered as cause of malaria since ancient times and is the leading cause of mortality worldwide, infecting approximately 3.3 billion people were at risk globally in 2011 (1 - 3). Both treatment and control of malaria are hampered by the spread of resis... |
Catheter ablation has become a standard therapy in the treatment of many arrhythmias . While different ablation strategies have been proposed and are currently applied, all ablation procedures share one commonality in their necessity for the use of fluoroscopy to visualize catheters . Heavy reliance on the use of live ... |
The purpose of this article is to describe a new surgical method of arthroscopy assisted treatment of intraarticular proximal tibial fractures (arif arthroscopic reduction and internal fixation), analyzing its efficiency and safety on a series of patients . The proximal tibia is vulnerable because of its anatomical pos... |
The data file of recommendations by pbac was created by abstracting data from the pbac web site (http://www.health.gov.au/internet/main/publishing.nsf/content/public-summary-documents-by-product). Data were taken from recommendations made from july 2005 through november 2009 . In the data if a product had more than one... |
Interstitial pneumonitis is a classical complication of many drugs.pulmonary toxicity due to 5-azacytidine is rarely mentioned.it is important to anticipate diagnosis of 5-azacitidine - associated interstitial lung disease to limit antibiotics abuse and to set up emergency treatment . Pneumonitis, often called intersti... |
Apixaban, an oral direct factor xa inhibitor, is indicated for the prevention of stroke and systemic embolism in nonvalvular atrial fibrillation (nvaf).14 apixaban has also been approved for the prophylaxis of deep vein thrombosis (dvt) in patients who have undergone hip or knee replacement surgery,1,2,57 as well as fo... |
Toxoplasma gondii is an obligate intracellular parasite that actively invades host cells through a sequential secretion of proteins from apicomplexa - specific secretory organelles, namely, micronemes and rhoptries as well as by the participation of the parasite motility based on its subpellicular cytoskeleton . The hi... |
Acanthosis nigricans (an) is a cutaneous eruption characterised by symmetric velvety hyperpigmented, verrucous plaques of the intertriginous surfaces of the axilla, neck, inframammary, and mucocutaneous regions and can be classified as benign or malignant . Benign cases are typically associated with obesity and insulin... |
Measurement of cardiac output (co) requires use of invasive or minimally invasive devices; the use of noninvasive and minimally invasive devices has gained popularity in recent years . The bioreactance technique is a relatively new, continuous, totally non - invasive technique for measuring co that is easily implemente... |
Increased writing activity is seldom seen in neurological conditions, except in some patients with cerebrovascular disease, frontal - type dementia, temporal lobe epilepsy, and parkinson's disease . We report a patient with a left inferior capsular genu infarction who developed abulia and increased writing activity, si... |
During the past decade, advances in synthesis and biofunctionalization of colloidal semiconductor nanocrystals have generated an increasing widespread interest among investigators in the field of biology and medicine . The multitude of successful uses of quantum dots (qds) as specific markers for cellular structures an... |
Hydroxyapatite (hap) with multiple substitutions at all sites and containing ~4% to 6% carbonate is the primary component of bones (70% wt) and teeth (96% wt) [1, 2]. Several authors have reported on the structure and properties of human dental carbonate hap [35]. They study the enamel part of the tooth with a focus on... |
Usually the course of ns in children is chronic with periods of recurrence and if untreated, it will lead to end - stage renal disease (esrd) and death . Now oral corticosteroids are the first line treatment of ns and the majority of these children respond to steroids . About 12 - 22% of the children with ns are steroi... |
Different countries appear to differ significantly with respect to rates of permanent pacemaker (ppm) implantations . For example, the number of ppm implantations per capita is much lower in the populations of asian countries than in western populations . According to the 2009 11th world survey of arrhythmias project,1... |
It is estimated to be the most common cause of neonatal hospital readmission in north america (1). It may lead to bilirubin accumulation in basal ganglia and brain stem nuclei and lead to kernicterus . If the infants survive the acute phase, which is marked by lethargy, hypotonia, poor feeding and opisthotonus, they ma... |
Evidence is increasing that asthma is a heterogeneous disease constituted by overlapping separate syndromes with probably different, but yet undefined, causes and natural histories . There is a need to identify each of these groups of patients (the so - called asthma phenotypes), whose clinical and prognostic character... |
Stress factors in operation room and block level mismatch with surgical area may contribute to discomfort, anxiety and restlessness in patients under spinal anaesthesia . It may provide freedom from specific discomfort and can impart some amnesia for the block procedure and surgical operation . Thus, judicious use of s... |
All mice were housed and bred in a specific pathogen - free facility and used at 412 wk of age . Tcr mice (21) were obtained from the jackson laboratory (bar harbor, me). Tcr mice (22) were mated with rag2 mice (23) to generate double - deficient rag2tcr mice . Mice transgenic for a chimeric protein consisting of the e... |
Alzheimer disease (ad) is a rapidly expanding health crisis affecting over 26 million people, with the prevalence expected to rise dramatically (brookmeyer et al ., 2007). Research examining ad biomarkers suggests a rise in underlying pathology a decade or more before the onset of dementia, and continuing throughout th... |
Periprosthetic joint infection (pji) is a devastating complication seen in total joint arthroplasty (tja) patients . It could lead to prolonged hospitalization, repeated surgical intervention, significant permanent deformity, or even definitive loss of the implant . The symptoms of pji are often nonspecific, which make... |
One - dimensional (1d) nanostructures such as nanorods, nanowires and nanotubes have attracted attention due to their novel physical and chemical properties as well as their potential use in a wide range of advanced applications in the past decade . As a consequence, many synthetic methods have been developed to prepar... |
The study was approved by the joint ethics committee of the institute of neurology and the national hospital for neurology and neurosurgery, london, uk . All structural and functional scans at time 1 and time 2 were acquired from the same siemens 1.5 t sonata mri scanner (siemens medical systems, erlangen, germany). Th... |
Oral health status has a major impact on the general feature of life and well - being . With the increasing rate of oral diseases, the global necessity of effective and economical products for prevention and treatment has intensified . This calls for an understanding of traditional practices and oral health beliefs . U... |
Cystinuria is an autosomal recessive genetic disorder that leads to defects in the transepithelial transporters for the dibasic amino acids, including cystine, ornithine, lysine, and arginine . The urine concentrations of those amino acids in cystinuric patients become elevated as a result of impaired reabsorption from... |
Diabetic peripheral neuropathy (dpn) is a late - stage microvascular complication that develops in nearly 50% patients during the course of type 2 diabetes mellitus (t2 dm), affecting particularly low extremities . Dpn is characterized by irreversible nerve structural and functional changes due to demyelination, axonal... |
Takayasu s arteritis is a granulomatous vasculitis of unknown etiology that affects mainly the aorta and its branches . As a result of intimal fibroproliferation, segmental stenosis, occlusion, dilatation, and aneurysmal formation of the involved vessels it is an uncommon disease, with an approximate incidence of 23 ca... |
In the previous issue of critical care, rhodes and colleagues report on significantly increased levels of circulating dna in patients admitted to the intensive care unit (icu) in comparison with healthy controls . They show plasma dna levels to be an independent predictor of mortality and the development of sepsis in t... |
Patients with end - stage renal disease treated with intermittent hemodialysis (hd) have to maintain proper fluid volume balance, which should be achieved by daily restrictions in fluid consumption . The improper drinking behaviors seen in this group of patients leads to chronic fluid overload, which may result in unco... |
Samples of stem, root, and leafy branches preserved in 70% ethanol were collected from a population near saipipi, savaii, samoa . A healer preparation from falealupo prostratin (1) was detected in each sample, and these materials were used for method development and validation . Another collecting expedition was made t... |
Continuous phase transitions can be characterised by an order parameter which changes from zero above the critical temperature to a finite value below tc . The landau theory of phase transitions allows a very succinct phenomenological description of such phase transitions . It uses an expansion of the free energy of th... |
The leading cause of nontraumatic extremity amputation is complications of diabetes, with over 96,000 amputations per year.1 neuropathy associated with diabetes predisposes to pain, numbness, ulceration, infection, gangrene, and amputation . Somatic and autonomic diabetic neuropathy contribute to 87% of these amputatio... |
Patients with cancer who undergo complex treatments may experience psychological distress, but it is often unrecognized, and if left untreated may contribute to poor health outcomes among patients and their caregivers . Evidence - based distress management guidelines, developed by the national comprehensive cancer netw... |
Mast cells are long - lived resident tissue cells distributed throughout vascularized connective tissues and are especially numerous near surfaces exposed to the environment, including the skin, the respiratory system, the gastrointestinal and genitourinary tracts, i.e. At the portals of pathogen entry . These cells ar... |
Acute coronary syndrome (acs) is a significant cause of morbidity and mortality in patients with coronary heart diseases . It is important to identify high - risk patients and determine who will be treated immediately in acs . Red cell distribution width (rdw) and fragmented qrs (fqrs) complexes are predictors of cardi... |
Epilepsy is a group of conditions characterized by recurrent, unprovoked seizures that result from abnormal synchronized neuronal firing in the brain . Epilepsy will affect up to 1 in 26 individuals and confers a significant health and economic burden . There are many forms of epilepsy that can be distinguished by vari... |
Various mechanical and chemical surface modifications of titanium dental implants, such as blasting, alkaline treatment, or hydroxyapatite coating, have been reported for improving the bone response during healing process [14]. Some reported the effectiveness of the surface coating or immobilization with cell adhesive ... |
Cancer, which is commonly a harbinger of imminent patient death, is a group of diseases characterized by uncontrolled growth and spread of abnormal cells and aberrant cell behavior, which leads to expansive masses that destroy surrounding normal tissue and is able to attack vital organs resulting in disseminated diseas... |
The subjects of this comparative study were primary and preschool aged children (6 - 9 year - old) selected from the 1st and 2nd educational district of yazd, southeast iran . For sampling, the list of children with the above conditions was prepared . In the next step, for muster of comparison group, 30 children were s... |
Several diseases are associated with the extracellular deposition of protein aggregates, including the alzheimer's disease, the transthyretin, and light chain amyloidoses as well as type ii diabetes . Accumulation of insoluble protein in the extracellular space results from the aberrant assembly of proteins into aggreg... |
Osteonecrosis of the femoral head (onfh) is a common disease in orthopedics throughout the world . Various accepted risks factors, including trauma, excessive steroid use, alcoholism, damage from radiation, sickle cell anemia, gaucher's disease, and the exposure to high pressures, are reported [17]. Chronic groin pain ... |
Tetanus is a severe acute infection caused by the exotoxins produced by an anaerobic, gram - positive bacillus . In developed countries, the rate of death from tetanus is 32% among cases reported in recent years.1 most tetanus cases (approximately 70%80% of cases) result from minor wounds (cuts, scratches, and so on). ... |
Lithium salts have a long history of human consumption beginning in the 1800s . In psychiatry, they have been used to treat mania and as a prophylactic for depression since the mid-20th century . Today, lithium salts are used as a mood stabilizer for the treatment of bipolar disorder and also, off - label, for other ps... |
H3.3 is incorporated throughout the cell cycle [2, 4], particularly in regions of the genome in which histones need to be displaced, such as transcribed genes or regulatory elements [5, 6]. Incorporation in these contexts depends on the histone chaperone hira and helps maintain chromatin structure by filling gaps left ... |
Rheumatoid arthritis (ra), as other autoimmune systemic diseases, is associated with increased cardiovascular morbidity and mortality, mostly attributable to accelerated atherosclerotic process . Data in the literature demonstrated that inflammatory nature of ra contributes to the excess of atherosclerosis observed in ... |
Ng2 cells (neuron - glia chondroitin sulphate proteoglycan 2), also referred to as synantocytes, polydendrocytes, -astrocytes, oligodendrocyte precursor cells (opc) have been recognized as the fourth type of glial cells in the mammalian central nervous system, representing about 58% of the glial cell population . Morph... |
The nonclassical hla - g molecule presents several properties that differ from other classical class i hla (-a, -b, and -c) molecules, including restricted tissue distribution; limited protein variability; presence of several membrane - bound and soluble isoforms; unique molecular structure, presenting a particular pep... |
Eu2o3 doped zno films are deposited on cleaned quartz substrate at room temperature (300 k) using radio frequency (rf) magnetron sputtering technique (rf frequency: 13.56 mhz). Pressed zno powder (aldrich 99.99%) with various europium oxide concentrations is used as the target for sputtering . The eu2o3 doping concentr... |
The countermovement jump (cmj) is an explosive movement that is essential in many sports, including basketball and volleyball1 . Cmj height, which is determined by measuring the jump height starting from an erect position followed by a downward movement before starting to push off, is an important criterion in athletic... |
There is an increase in the use of angiotensin ii type 1 receptor antagonists (at ii antagonists) and angiotensin - converting enzyme inhibitors (ace - inhibitors) as prophylactic treatment of migraines, in addition to their use as antihypertensives . These drugs pass the placenta and have highly adverse effects on the... |
Deoxyribonucleic acid (dna), the basic substance of life, changes over the long term in the process of evolution, but strict homeostasis of dna is important over the short term for the maintenance of individual organisms . Dna damage is thought to occur at the rate of tens of thousands events daily in each cell (endoge... |
A healthy 15-year - old woman was admitted to the department of neurosurgery of our institution with a chief complaint of a 1-month history of headache and dizziness . 1) demonstrated a 6.85 cm - sized, solid and cystic intra - axial mass in the right temporooccipital area, compressing the posterior horn of the right l... |
We retrospectively reviewed seventeen infants with hydrocephalus who were treated in our department by etv from jul . This study included 17 patients between the ages of 51 days and 337 days, with an average age of 143 days, 9 males and 8 females, 4 han people and 13 hui people . Of the 17 patients there were 5 cases w... |
Thymoma is an uncommon neoplasm of the thymus, derived from the thymic epithelial cells . Myasthenia gravis (mg) is the most common paraneoplastic neurological disorder associated with thymoma . About 3050% of thymoma patients mg with thymoma is particularly associated with autoantibodies against postsynaptic nicotinic... |
To estimate population exposure of apes and owm species in africa to evs, we conducted a seroepidemiologic study of serotype - specific neutralizing antibodies against 3 ev types . These seroprevalences were compared with seroprevalences in human populations in areas where primates also lived (cameroon, zimbabwe, and s... |
The dissemination of hepatitis viruses among patients in hemodialysis (hd) centers is one of the most important causes of morbidity and mortality in end stage renal disease patients . While the introduction of vaccination programs and isolation of hd machines have limited the spread of hbv infection, its prevalence rat... |
Compounds with metals as therapeutic agents for various diseases states have been investigated in the last few decades [13]. Metals can react with different atoms of many amino acids residues in proteins providing therapeutic actions . Because of their different mechanism of actions, the development of metal complexes ... |
. Two of the most well - known chronic respiratory diseases are asthma and chronic obstructive pulmonary disease (copd). Over 235 million people currently suffer from asthma worldwide, and it is the most common chronic disease amongst children . It is estimated that 600 million people suffer some form of copd, while ne... |
Bullous systemic lupus erythematosus (bsle) is a subepidermal blistering disease that occurs in a subset of patients with systemic lupus erythematosus (sle) [1, 2]. Cutaneous lesions are reported during the course of sle in 76% of patients; however, it has been reported that bsle is very rare and occurs in less than 1%... |
In their companion article, tononi and cirelli argue that i have missed the big picture by conflating questions of sleep function with the underlying mechanisms . As i have discussed elsewhere [2, 3], understanding sleep function is of central importance to biology . Any theory of sleep function must also grapple with ... |
In order to assure the continuing downscaling of electronic components, new growth methods need to be explored as currently used top - down techniques are approaching their physical limits . An emerging alternative for the growth of nanoscale systems is self - assembly: by exploiting the striving toward the minimal ene... |
Pulmonary embolism is a common and potentially lethal disorder that frequently recurs and is associated with long - term impairment and suffering . The overall mortality rate of patients with untreated pulmonary embolism is approximately 30%; however, prompt diagnosis and appropriate therapy can reduce the mortality ra... |
It is well known that uvci could happen post acd / f [17]. An incidence of 24.2% has been reported in one prospective study when including the clinically unapparent injury . Only two cases of bilateral vocal cord injury (bvci) have been described in the english literature . One was after a whiplash injury which, by its... |
The endothelial cell dysfunction is observed in myopia and in contact lens wearers [2, 3]. The decreasing number of endothelial cells can also be a result of a surgical injury related to the opening of the anterior chamber . Many studies have shown that even minor changes in the morphology of the endothelial cells may ... |
Congenital myasthenic syndromes (cmss) are a group of rare genetic disorders affecting neuromuscular junction transmission . The subtype of cms depends on whether the defect is presynaptic, synaptic, or postsynaptic . In the past 33 years, at least 23 genes encoding proteins of the neuromuscular junction have been iden... |
Scabies, due to infestation with the sarcoptes scabiei mite, has been estimated to affect approximately 300 million people worldwide each year . Its direct impact is itching, but secondary bacterial infection with streptococci and staphylococci is frequent and can lead to serious and potentially fatal complications, in... |
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