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The revolution in hiv treatment brought about by combination antiretroviral therapy in 1996 had altered the course of the disease among those living with hiv in high - income countries but had only reached a fraction of people in low- and middle - income countries . In resource - poor countries, access to antiretrovira... |
Nonalcoholic fatty liver disease (nafld) is one of the most common chronic liver diseases in the worldwide and it is associated with chronic diseases such as diabetes and heart disease . Nafld is associated with insulin resistance and is defined as fat accumulation in liver, exceeding 5% of liver weight, in the absence... |
Various studies have investigated the role of human papillomavirus (hpv) in oral squamous cells carcinoma (oscc) but the results are highly controversial . Most reports have shown that hpv 16 is the most prevalent type in both oral and genital tumors1 . Abnormalities in several components of the cell - cycle regulatory... |
To analyze nvt penicillin - nonsusceptible pneumococcus (pnsp) detected in patients with invasive pneumococcal disease, we used data from the active bacterial core surveillance (abcs) system, a population- and laboratory - based collaborative system between the centers for disease control and prevention and state healt... |
Overweight and obesity are pandemic conditions associated to increased risk for type 2 diabetes, cardiovascular disease, cancer and all cause - mortality [2, 3], and a dramatic increase in public health expense to their management [4, 5]. Mediterranean diet seems to be a model to preserve a good health, especially when... |
Seizure is one of the most common problems in pediatric neurology which occurs in 4 - 10 percent of children in the first 16 years of life . A detailed and reliable account of the event by an eyewitness is the most important part of the diagnostic evaluation, but it may not often be available . Electroencephalography (... |
Hyperpigmentation of the gingiva has always been a concern to certain patients, especially young females . Although melanin pigmentation of the gingiva is completely benign and does not present a medical problem, its unaesthetic appearance as black gums is more pronounced in patients having a high smile line (gummy smi... |
Charging of grains of identical insulating materials during collisions has been of considerable interest recently, both for its intrinsic physics and for its applications to situations ranging from volcanic dust plumes and desert sandstorms to industrial powder processing . However, work up to now has not explained why... |
Cervical cancer is the third most commonly diagnosed cancer and the fourth leading cause of cancer death in females worldwide, despite improvements in screening programs, which have allowed the diagnosis of preinvasive lesions and reduced the incidence of advanced stage cervical cancer . Several features of cervical ca... |
Studies have demonstrated that different ethnic groups may have different predisposing risk factors, epidemiologic patterns, and outcomes of stroke . This has been shown in african americans, caucasians, hispanics, arabs, and asians [16]. These differences could be due to differences in demographic or socioeconomic fac... |
Parry - romberg syndrome (prs), or progressive facial hemiatrophy, is a rare disorder presenting as a slowly progressive but self - limited atrophy of facial structures, sometimes followed by wasting of adjacent skin, connective or ocular tissue, muscle, cartilage, and bone1). Symptoms usually appear in the first or se... |
Operando uv / vis spectroscopy measurements were performed to study the hydrocarbon species trapped inside hsapo34 cages, together with mass spectrometry to follow product formation during the mto reaction . Timeresolved operando uv / vis spectra were recorded to monitor the reaction and regeneration under different re... |
Carcinosarcoma (also known as pseudosarcoma, pseudosarcomatous squamous cell carcinoma, pleomorphic carcinoma, and spindle cell carcinoma) is a highly malignant tumor characterized by dual malignant histologic differentiation of the epithelial component consisting of a focally squamous cell carcinoma and a mesenchymal ... |
Midgut malrotation (mmr) is a congenital nonrotation or incomplete rotation of the primitive intestinal loop around the axis of superior mesenteric artery (sma) during fetal development . Mmr is more known by pediatrics than adult surgeons because it occurs at a rate of about 1 in 500 live births . Up to now, surgical ... |
To present a unique case of a 58-year - old female with toxic anterior segment syndrome (tass), following a triple procedure: descemet's stripping automated endothelial keratoplasty (dsaek), phacoemulsification and posterior chamber intraocular lens implantation . The patient was treated with topical dexamethasone sodi... |
Inflammatory -cell inhibition and apoptosis are increasingly accepted as key contributors to failing insulin secretion leading to type 1 and type 2 diabetes [1, 2]. Interleukin-1, a 17 kda proinflammatory cytokine and mediator of inflammation, fever, and acute - phase responses [1, 3], inhibits -cell function in vitro ... |
Dental implantation is an effective therapeutic option to replace missing teeth in modern dentistry . In order for an implant to successfully sustain functional loads, there must be sufficient alveolar bone around the implant . Implants must be at least 5 mm wide and 7 - 10 mm in length1 . After implantation, dehiscenc... |
Prescription drugs are becoming the drugs of choice for adolescents and young adults with a reported increase in misuse of 212% from 1992 to 2003 . The substance abuse and mental health services administration and johnston et al . Have reported that the misuse or nonmedical use of prescription drugs has a greater preva... |
Cosmetotextiles are garments designed to contact the skin with the aim of transferring active substances useful for cosmetic purposes, particularly to combat ageing effects [14]. In fact, there are already several textile products on the market that claim to have certain properties that are usually found in pharmaceuti... |
The gene expression pathway initiates at nuclear transcription generating a pre - mrna, which very often undergoes splicing, post - transcriptional regulation, and then translation into a protein . During the pre - mrna splicing process, introns are removed and exons are joined in order to generate the mature mrna [13]... |
Animal welfare standards are becoming increasingly important even if there are different opinions in the definition of acceptable animal welfare conditions due to cultural, ethical or religious differences between individuals . The treaty of lisbon (european commission, 2007) recognizes animals as sentient beings, capa... |
Neurocognitive dysfunctions have received considerable attention as potential endophenotypic markers for bipolar disorder (bd) as these are seen in patients (during the euthymic phase) and in the first degree relatives . The various neurocognitive deficits in patients with bd include deficits in attention, processing s... |
The mucopolysaccharidoses (mps) are a family of genetic disorders characterized by changes in an individual s ability to metabolize mucopolysaccharides, which are complex sugar molecules found in the connective tissue, mucosal fluids, synovial fluid, and other cells throughout the body . There are six types of mps, wit... |
Access to adequate and safe blood transfusion facilities is integral to any basic health care delivery infrastructure . Blood transfusions are also inherently embedded with risks ranging in severity from minor to life threatening . Judicious patient selection with pragmatic pretransfusion assessments of risk versus ben... |
Surgical pathologic evaluation of axilla is a standard part of the management of breast - conserving therapy for breast cancer; this has both prognostic and therapeutic implications . While the presence of axillary lymph metastasis is the single most critical predictor of survival in breast cancer, the absolute number ... |
Aura is defined as attacks of reversible focal neurological symptoms (visual, sensory and/or speech symptoms) that last more than 5 min and no longer than 1 h. migraine - like headache usually occurs at the onset, during or follows aura symptoms . Patients with motor weakness, according to the present classification, a... |
The investigation of the structural - functional organization of chromatin in situ using conventional transmission electron microscopy has been hindered by a number of technical limitations . The major handicap derives from the fact that in most electron microscopy preparations, the agents employed for thin - section c... |
An hiv - negative male, in his sixties, originally presented with a 6-month history of an isolated large nodule on the right malleolar region which was confirmed as kaposi's sarcoma (ks) on excision . Subsequently he continued to develop more papules and plaques on the feet and over the following 7 years underwent exci... |
The question of why nature chose phosphate for life on earth has been around for many years . Phosphate diesters are especially adapted to link two nucleotides and still ionize, helping to stabilize the dna and rna for carrying and processing genetic information . Arsenic acid, which is the most closely related to phos... |
Cribriform - morular variant of papillary thyroid carcinoma (cmv - ptc) is a distinct ptc with a better prognosis . The affected patients have shown both germline and somatic mutations of adenomatous polyposis coli (apc) genes . Unlike classic ptc, we report a case of cmv - ptc in a patient with apc, comparing with its... |
Women have among the highest rates of new hiv infections globally and the rate of new infections has not lessened in recent years [14]. African americans account for 66% of new hiv infections among all us women over 5 times their proportion representation (12%) in the population . One in 30 african - american women can... |
Taking advantage of the widespread symbiotic interactions pre - existing between yeast and drosophila, we have recently developed an oral delivery method to induce rna interference (rnai) in a pest insect by knocking down essential genes expressed in its digestive tract (fig . 1). By feeding d. suzukii with saccharomyc... |
As mentioned by triantafillidou and tsoumakas review (2006), in greece, alcohol use and abuse by adolescents is an important problem, mainly in suburban and rural areas . In risk factors for starting drinking alcohol family, relations with peers, risky behaviors, genetic reasons and advertisements moreover, adolescents... |
Bone marrow is the major hematopoietic organ . Bone marrow hematopoietic tissues are highly sensitive to toxins, including radiation and chemotherapeutics, which may induce myelosuppression . The cytoactivities of primitive hematopoietic cells may, therefore, be depressed, and the number of peripheral blood cells may d... |
Modern western society is obsessed with achievement, youth, and beauty . Since the latter half of the 20th century there has been an increasing focus on the body as a vehicle for identity and self expression, with a greater recognition of the role of appearance and the desire for self improvement . This contrasts with ... |
Cataract is considered as a major cause of visual impairment in diabetic patients, as the incidence and progression of cataract is increasingly elevated in patients with diabetes mellitus . Recently, cataract surgery is an effective and the most common surgical ophthalmic procedure worldwide . However, the elucidation ... |
A total of 1,217 dead birds were shipped at 4c to the tropical medicine institute " pedro kouri " and identified by ornithology experts . Brain, heart, and kidneys were removed and tested for wnv by using reverse transcription polymerase chain reaction (rt - pcr) (12). Briefly, rna was extracted by using the qiamp vira... |
There are three distinct components of reduction in airway caliber: secretions, smooth muscle contraction and airway wall thickening . While pathogenetic changes that bring about airway narrowing may be heterogeneous, it is generally accepted that inflammatory cell infiltration with secretion of pro - inflammatory cyto... |
The combination of a sulfonylurea and a thiazolidinedione may be a particularly effective treatment option in the early stages of type 2 diabetes when -cell function is at its highest . This allows maximal benefit to be obtained from the insulin secretion - promoting abilities of the sulphonylureas and the -cell - prot... |
Cavernous hemangioma is a benign vascular malformation and belongs to a wide and continuous overlapping spectrum of hamartomas . Most cavernous haemangiomas occur in the vertebral body and may extend into the epidural space . Purely extradural cavernous hemangiomas without any vertebral body involvement is extremely ra... |
Periodontitis is a chronic immunoinflammatory infectious disease leading to the destruction of periodontal ligament and adjacent supportive alveolar bone induced by pathogenic biofilms containing numerous periodontal pathogens . Among the periodontal pathogens, porphyromonas gingivalis, treponema denticola and tannerel... |
Sleep disturbance is associated with many complications and decreased efficiency during the day, increased somnolence and reaction time, and reduced power of making correct and timely decisions (1). Sleep and poor quality sleep can result from physical discomfort and be a side effect of drugs and mental disorders, such... |
The intestinal epithelium is the largest surface area of the human body in direct contact with the external environment and exposed to a multitude of foreign microorganisms, macromolecules, and xenobiotics . As such, a fine regulation of gut mucosal immune functions is needed to develop a prompt and self - limiting inf... |
From the first reported infected patient in may 2009 through january 2010, a total of 740,835 patients in south korea were reported as having pandemic (h1n1) 2009 virus infection . A total of 225 patients (0.03%) died of disease related to pandemic (h1n1) 2009 . During this period, physicians in local clinics and terti... |
Prostate cancer is the most commonly diagnosed solid cancer in men, with 220,800 estimated new cases and 27,540 estimated deaths in the united states recorded in 2015 . Globocan 2012 sources estimate prostate cancer incidence in the european union at 345,195 new cases, with a crude rate of 139, making it the most commo... |
Hepatitis b virus is a potentially life - threatening cause of liver disease in the world . It both causes chronic infection and puts people at high risk of death from cirrhosis and liver cancer . Globally, it is estimated that more than 2 billion people are still living with hbv infection . Over 350 million are believ... |
Adenoviruses are viral pathogens that target a variety of organs in the human body [1, 2]. They are highly contagious and can be deadly against patients with a compromised immune system [1, 37]. There are over 50 serotypes of adenovirus (ad), divided among 7 species (a g) [1, 35, 715]. Species b viruses are distinguish... |
Propofol is a short - acting intravenous hypnotic agent, which is widely used for sedation and general anesthesia . However, pain during injection of propofol can occur in up to 80% of patients, which can be very stressful to patients . Many methods including cooling or diluting the propofol solution or the concomitant... |
Over - the - counter cold medicines, which contain amantadine, are widely used in the people s republic of china . Clinicians are familiar with the psychosis caused by long - term treatment with amantadine, especially in elderly patients; however, early - onset psychotic complications among healthy young individuals ha... |
Anteromedial, anterolateral, and superomedial portals were created and a diagnostic arthroscopy was performed . The presence of a concomitant injury to the ligament or cartilage was assessed and meniscal tear was identified . Unstable fragments and fibrous tissues were removed with a motorized shaver, rasp, or basket f... |
Durable left ventricular assist devices (lvads) improve the quality and length of life by restoring normal circulation in the majority of recipients1 . Since the introduction of smaller and more durable continuousflow lvads, there has been a steady decline in adverse event rates and, consequently, better survival rates... |
A rare condition in newborns called congenital chylothorax (cc) occurs when lymphatic fluid accumulates within the pleural cavity . Here is a presentation of a birth traumatic case with bilateral pleural effusion successfully treated by octreotide . A 3100-g - term male newborn delivered vaginally from a 33-year - old ... |
Russell body duodenitis (rbd) is a rare inflammatory disease characterized by an abundance of polyclonal plasma cells present in the duodenal mucosa . These plasma cells contain intracytoplasmic eosinophilic globules of condensed immunoglobulin, the so - called russell body . We describe the case of a patient with rbd ... |
Polycyclic aromatic hydrocarbons (pahs) are ubiquitous semi - volatile environmental contaminants (1, 2) and have been often monitored in water, air, soil and food matrices (3). They are principally by - product of incomplete combustion of organic substances and also generated by fossil fuels or plants burning . Due to... |
Mycobacterium avium complex (mac) contains clinically important nontuberculous mycobacteria and is the second largest medical complex in the mycobacterium genus after the mycobacterium tuberculosis (mtb) complex . Mac affects patients with chronic obstructive pulmonary disease and cystic fibrosis, as well as immunosupp... |
Efforts to improve the outcomes of surgical coronary revascularization have taken many forms, but among the most successful have been bilateral internal mammary artery (i m a) and radial artery (ra) grafts . It has been clear for some time that saphenous vein conduits have limited life span, and that multiple i m a s i... |
Protection of human health and the environment is one of the major challenges facing developing as well as developed countries of the world [15]. The original aim of regulating waste disposal is to reduce the introduction of polluting substances into the atmosphere since protection of the environment is a major challen... |
Laser - assisted in situ keratomileusis (lasik) is the most common surgical technique for correcting refractive defects and although its efficacy and safety have already been proven, it is not free of potential complications . One of the most feared is postoperative ectasia which induces astigmatism and myopia and redu... |
Interest in erosion has increased as there has been a rise in its incidence in the younger population . Previously erosive challenges in the cervical area were reported mostly in elderly people, whose teeth had become non - functional . However, it has been shown that dietary changes and inadequate oral hygiene have le... |
Intrathecal baclofen (itb) is becoming a popular modality for management of severe spasticity [13]. Spasticity is defined as hypertonia in which one or both of the following signs are present (1) resistance to externally imposed movement that increases with increasing speed of stretch and varies with the direction of j... |
Essential tremor (et) is one of the most common kinetic disorders, and inversely depends on age . An et is a kinetic tremor that commonly occurs in the arms during voluntary movements such as pouring, drinking, eating, writing, and other daily activities, but especially occurs in the head, neck, and voice, and occasion... |
Lymph nodes of the axilla have been studied in the context of breast cancer since before halsted published his study proposing that this lymphatic drainage was a pathway for metastasis and recommending axillary node dissection (and). Sentinel lymph node biopsies (snb) allowed for detection of smaller micrometastases th... |
Obstetric and gynecologic physiotherapy is a subspecialty in physiotherapy concerned with promotion of health throughout the child - bearing period, and helps the mother to adjust advantageously to the physical and psychologic changes of pregnancy and the post - natal period, so that the stresses of child - bearing are... |
A 32-year old male patient visited our institution with the chief complaint of pain in the right hip and the lower back which started after he had experienced a minor traffic accident ten months prior to his visit . The pain became severe when he bent his waist, and an paresthesia was found with a numbness going to the... |
The incidence of delirium in the intensive care unit (icu) ranges from 45% to 87% . Delirium is an independent risk factor for death in the icu, and can result in over sedation, increased duration of mechanical ventilation and increased length of icu stay . Risk factors for delirium include metabolic impairment, substa... |
Laparoscopic sleeve gastrectomy (lsg) is currently one of the most commonly performed bariatric surgeries in the world . Known perioperative complications include haemorrhage, leak, small bowel obstruction and infections (mostly wound and intra - abdominal abscess). Intra - abdominal abscess presents in <1% of all proc... |
Besides its classical role in calcium and bone homeostasis, vitamin d is considered a potent immunomodulator that can affect the pathogenesis of several autoimmune diseases . Our aim is to evaluate the effect of vitamin d correction to a patient with new onset graves disease (gd) with an underlying vitamin d deficiency... |
Obesity has reached epidemic proportions in the united states, with recent data indicating that more than 78 million adults (36%) and 12.5 million children and adolescents (17%) in the united states have this disorder [1, 2]. The enormous health and economic tolls of obesity and its profound adverse effects on quality ... |
Keratoconus is described as a degenerative bilateral, progressive, noninflammatory corneal disorder characterized by ectasia, thinning, and increased curvature.1,2 it is associated with loss of visual acuity particularly in relation to progressive cornea irregularity,3,4 and usually is manifested asymmetrically between... |
Il-8 also possesses a clear role in eosinophil chemotaxis in allergic respiratory diseases [2, 3]. On the other hand, il-15 effect on human eosinophil is through inhibition of the spontaneous apoptosis via the autocrine production of gm - csf and thus may perpetuate allergic inflammation by prolonged eosinophil surviva... |
Osteoporosis - related fractures are a major public health problem mainly in postmenopausal women and the elderly . Osteoporosis affects an estimated of 75 million people in europe, united states of america, and japan . There are several treatment options available including calcium, vitamin d, parathyroid hormone, str... |
Prescription writing is a complex and challenging task that requires diagnostic skills, knowledge of medicines, communication skills, an understanding of the principles of clinical pharmacology, and appreciation of risk . In recent years, medical researchers observe deficiencies in health care occurring due to many pre... |
It was recently suggested that endometriosis may commence as an endometrial disease provoked by the aberrant expression of aromatase in this tissue, as this appears to play a pivotal role in its survival in ectopic locations.4 gene array studies have shown that the expression profiles of endometriosis lesions and the e... |
The preventive strategy for cervical cancer is based on identification and treatment of high - grade cervical lesions (hg - cin) in order to prevent cancer progression . Thus, although conservative, it represents a surgically - based approach (usually by means of laser, cold - knife cone biopsy, or loop electrosurgical... |
Water disturbance may occur in hemorrhagic and ischemic stroke patients because of the major role that the central nervous system plays in water homeostasis [13]. Post - stroke hypernatremia is generally the consequence of central diabetes insipidus, but it can also take place if the patients do not have free water acc... |
Although the prevalence of early onset dementia (eod) (dementia in individuals <65 years old) was once assumed to be very low, additional data have shown that prevalence has varied between 15.143.9/100,000 for early onset alzheimer s disease (ad),1 while the prevalence of frontotemporal dementia (ftd) has varied from 2... |
Osteoarthritis (oa) of the hip induces regressive changes in the hip joint cartilage and subsequent abnormality in the synovial membrane and articular capsule, leading to the impairment of joint function, and osseous changes also occur . The prevalence of this disease is not high,1 but coxalgia and surrounding pain and... |
In the elderly, frailty is an extremely common clinical state and a serious health problem in which there is an increase in an individual's vulnerability for developing increased dependency and/or mortality when exposed to a stressor [1, 2]. Overall, it appears that low levels of vitamin d play an important role in fra... |
Surgical goals and patient expectations of cataract surgery have evolved considerably over the past decade . Many patients now desire spectacle independence not only for distance but also for near and intermediate vision . Multifocal intraocular lenses (iols)1 provide spectacle independence by producing two or more foc... |
Melanoma is the malignant tumor of melanocytes which may present in a wide morphological spectrum including highly pigmented to amelanotic appearance . Clinically there are four main subtypes of cutaneous melanoma: superficial spreading melanoma, lentiginous melanoma, nodular melanoma and acral lentiginous melanoma . T... |
Since 1997, there were many changes in the employer practices affecting the organization of work in both the developed and developing countries from economic crisis . Thailand being a developing country is of no exception in such economic crisis (1, 2). One of these changes has been often - repeated rounds of downsizin... |
Giant inflammatory (filiform) polyposis is an uncommon benign lesion and is usually associated with inflammatory bowel disease (ibd). Long - term inflammation of the colonic mucosa during chronic ibd with alternating periods of ulceration and healing may lead to the formation of finger - like projections [1, 2]. In rar... |
The human jurkat t cell line was maintained in rpmi 1640 medium supplemented with 10% fcs, 10 mm hepes, and antibiotics (all from gibco brl, eggenstein, germany). The cd95-resistant jurkat subline jurkat - r was generated by continuous culture in the presence of anti - cd95 mab (igg3, 1 g / ml; cell diagnostica, mnster... |
Throughout the world rapid population ageing is occurring, with a large proportion of older adults preferring to stay living at home . Most older people experience one to three chronic diseases and, in very advanced age, frailty, disability, and social isolation are common . At the same time there are increasing demand... |
Celiac disease (cd) is an immune - based enteropathy triggered by dietary wheat gluten and similar proteins in barley and rye in genetically susceptible individuals . Recently, the espghn (european society of paediatric gastroenterology, hepatology and nutrition) proposed that cd may be defined as an immune - mediated ... |
Patients with end - stage renal disease (esrd) on hemodialysis (hd) have very high cardiovascular mortality . Interestingly, the usual risk factors for atherosclerotic diseases in the general population fail to explain the increased cardiovascular mortality in the hd population . For example, unlike the general populat... |
Nanotechnology is considered as a cutting edge technology in the 21 century . In ancient period also people prepared and used nanoparticles in different fields of art and medicine, without knowing their in - depth physico - chemical properties, but believing their potential to prevent diseases . Window glasses and cera... |
Bicuspid aortic valve is an autosomal dominant hereditary disease with incomplete penetrance and represents the most common congenital disease that can be found in the general population, with prevalence between 1% and 2% . However, a threefold higher male predominance one was observed, suggesting that this disease may... |
The first macrolide, erythromycin, was discovered in 1952 and since then macrolides have had an important role in treating infectious diseases (kirst, 2002). Erythromycin had moderate activity against gram - positive pathogens, while the newer semi - synthetic derivatives azithromycin, clarithromycin, and ketolides hav... |
A minor change in the thyroid hormone concentration has been reported with changes in cognitive and affective functions . Hashimoto's encephalopathy was first reported in 1966 and was associated with hashimoto's thyroiditis . Although it is a controversial disorder, hashimoto's encephalopathy is considered an autoimmun... |
Despite advances in total hip arthroplasty (tha), severe developmental dysplasia of the hip continues to pose a challenge to the orthopedic community.123 there are many anatomic deformities in a dysplastic hip, including increased proximal femoral anteversion, deficient acetabular bone, a small and narrow femoral canal... |
A 38-year - old male patient was referred to asan medical center due to severe shock attributable to contained aortic rupture around the aortic root . The patient had been treated with systemic corticosteroids after being diagnosed with behcet s disease 14 years previously . The patient had previously undergone aortic ... |
Deafness or hearing loss can be due to genetic or environmental causes or a combination of both . The genetic hearing loss is classified as syndromic or nonsyndromic . Among the many disorders classified as syndromic hearing loss, the pathology varies widely, but in nonsyndromic hearing loss, the defect is generally se... |
Unilateral absence of pulmonary artery (uapa) is a rare congenital abnormality, with an estimated prevalence of 1 in 200,000 . Some patients with uapa are totally asymptomatic while others may have severe pulmonary hypertension, hemoptysis, congestive heart failure, and cyanosis . We report a 2.5-year - old girl with c... |
The principal types of cells present in the blood are red blood cells (rbc), wbcs, and platelets . The percentage of wbc subtypes observed in human blood normally ranges between the following values: neutrophils 50 - 70%, eosinophils 1 - 5%, basophils 0 - 1%, monocytes 2 - 10%, lymphocytes 20 - 45% . The observation of... |
Inflammatory bowel disease (ibd) is a chronic and multifactorial gastrointestinal inflammatory condition that is clinically categorized as ulcerative colitis (uc) or crohn's disease (cd). Ibd fibrosis can occur in both uc and cd, but it is much more prevalent in cd . Typical cd presentations include discontinuous invol... |
Electroencephalographic (eeg) recordings of brain activity are dominated by periods of rhythmic activity . This activity is seen across a very broad range of frequencies, from <1 hz, up to> 100 hz . Spectral analysis of long epochs of eeg activity (> 1 min) reveal relationship between power and frequency such that the ... |
Exchange experiments involving the transfer of heteronuclear longitudinal magnetization of product operator terms such as izsz or sz were introduced by montelione et al . To quantitate transitions between different conformations of biomolecules for which isolated resonances are observed (montelione and wagner 1989). Th... |
The information generated from the genome projects will be of the greatest value if it can be converted into functional data, particularly if this increases our understanding of normal gene function and allows strategies to be developed for prevention and treatment of human disease . Likewise, the output of genetic var... |
Neuroserpin, or proteinase inhibitor 12 (gene symbol serpini1), was first found in cultured chicken neuronal axons and is predominantly expressed in human neurons of both the central and peripheral nervous systems . Sequence analysis has shown that neuroserpin is a new member of an old proteinase family, the serine pro... |
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