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The use of accurate static references for centration, the improvement of accuracy of wavefront aberration measurements, and the refinement of ablation profiles are technological advances that have led the corneal refractive surgery to a high level of efficacy, predictability, and accuracy.13 specifically, these advance...
In different eukaryotic cells, glycosylated and non - glycosylated er - luminal as well as integral membrane proteins have been identified as erad substrates . Based on the location of the misfolded lesion in the protein that is subjected to disposal, eradl (lesion in the luminal region), eradc (defect in the cytoplasm...
The last two decades have been subject to an increase in social awareness regarding the rights of all workers about workplace health and safety . The laws and regulations in this area were established to protect workers and increase their welfare in the workplace . Irrespective of the context of the work environment, t...
The ocean components of the coupled model intercomparison project phase5 (cmip5) global climate models (gcms or climate models) used by the intergovernmental panel on climate change (ipcc) to publish their fifth assessment report have a coarse resolution (on the scale of 1) (frieler et al . This coarse resolution preve...
Cancer of the gastric stump in patients previously operated on for benign disease was first mentioned by balfour in 1922 and was subsequently described by several authors . Today, cancer of the gastric stump is no longer the great rarity it was once considered to be . Although the question whether gastric resection for...
Obesity is regarded as a medical condition characterized by excessive accumulation of body fat to the extent that it has an adverse effect on health . Body mass index (bmi), waist - hip ratio and body fat percentage are different measures used to identify obesity . An index of less than 18.5 can be considered underweig...
Animal studies and case reports have suggested that methylphenidate (mph) exerts adverse effects on the reproductive system or gonadal hormones . However, it is unclear whether mph treatment reduces testosterone levels in children with attention - deficit / hyperactivity disorder (adhd). In this prospective study, we p...
Malaria remains a serious health concern in sub - saharan africa . In cte d'ivoire, malaria accounts for 43% of outpatient visits with one - third of reported death in health facilities . Due to the development and increasing resistance of p. falciparum to various antimalarial drugs available, the who introduced and re...
A 46-year - old woman presented with intermittent right flank pain she had experienced for a year . Physical examination revealed no significant findings such as tenderness at the costovertebral angle area, a palpable mass, or peripheral lymphadenopathy . Urinalysis, a complete blood count, and routine blood biochemist...
The shs recruited a population based sample of 4,545 unrelated tribal members 45 year or older without regard to disease status from 13 tribal communities in arizona, oklahoma and north and south dakota . This study uses data from a clinical visit in 198991, which is the shs visit that has measures of urinary cadmium ....
Serious side effects hamper pharmacological treatment of psychiatric illnesses such as schizophrenia and bipolar disorder . All currently used second - generation antipsychotic drugs (sgads) including olanzapine are capable of triggering significant weight gain associated with adverse metabolic alterations [1, 2]. It h...
Stable dispersion of sub - micron solid particles in polymer melts and solutions can be achieved in the presence of favorable polymer particle interactions . Studying the rheological behavior of polymer composites reinforced with well - dispersed nanoparticles, often referred to as polymer nanocomposites (pncs), has be...
Genomic guanine cytosine (gc) content in prokaryotes has been studied for> 50 years . Since the pioneering works, which began in 1955 the first considerations of gc content evolution speculated on the absence of a selective force behind this pattern of gc content variability (sueoka 1962), a vision that was reinforced ...
Epidural anesthesia is the most commonly used technique for providing not only peri - operative surgical anesthesia but postoperative analgesia in lower abdominal and limb surgeries . Many techniques and drug regimens, with partial or greater success, have been tried from time to time to calm the patients and to elimin...
Expertise in the field of root canal morphology is crucial for successful endodontic treatment . To avoid endodontic failure, especially during root canal preparation and/or obturation, the practitioner must have ample knowledge of the root morphology . Due to each tooth's singularity, such characteristics increase the...
Genetic screening of the brca1 and brca2 genes is offered to families with high risk of breast and ovarian cancer . Besides clear pathogenic mutations and polymorphisms, unclassified variants (uvs) of unclear clinical relevance are found . Some of these uvs may result in aberrant splicing, by affecting the donor or acc...
Protein production production and purification of recombinant human tpp1 from a chinese hamster ovary (cho) expression system were conducted using modifications of methods described previously (9). Cells were cultured in 1050-cm roller bottles for 9 days with serum - free dulbecco's modified eagle's / f-12 medium conta...
Obesity is traditionally defined as a weight 20% above the ideal weight, which corresponds to the lowest death rate for individuals of a specific height, gender and age (1). More recent guidelines for obesity have introduced the use of a measurement known as body mass index (bmi), which is calculated by the individual'...
Women diagnosed with gynaecological cancer are at risk for depression, anxiety and impaired quality - of - life (qol) even after treatment .,,, overall survival and hrqol are important components of assessing the effects anti - cancer treatment . Post - radiotherapy qol is not only depends upon the clinical variable of...
Hypersexual disorder is primarily conceptualized as a disorder of sexual desire, with an impulsivity component . It has symptoms befalling impulsive, compulsive, and addiction domains such as recurrent and intense sexual thoughts, urges, or behaviors, inability to control or stop the sexual behavior, and repetitively e...
Hepatosplenic t cell lymphoma (hstl) is a rare but very aggressive peripheral t cell lymphoma whose initial silent clinical presentation unfortunately delays the diagnosis and worsens the prognosis of patient survival . We describe a case of a 62-year - old woman who presented at our clinic with a non - palpable purpur...
A series of data has accumulated over the past five years that raises questions about our current understanding of the transcriptional process and its regulation . Following the discovery of coactivators for nuclear receptors (nrs), we have been amazed at the plethora of these molecules that have been reported in the l...
Hyaluronic acid is a suitable tool for lip augmentation and reduction of fine lines; however, one must be aware of anatomic structures when injecting filler material into the lips and perioral area, and be familiar with the injection techniques . To increase the volume of the lips, a procedure called lip augmentation, ...
Charcot - marie - tooth (cmt), also known as hereditary motor and sensory neuropathy, is classified into two major categories: type 1 and type 2 based on the value of motor median nerve conduction velocity (ncv). Cmt1, also known as the demyelinating form of cmt, is clinically characterized by slow ncvs due to myelin s...
Tumor - bearing animals offer a variety of xenograft - based cancer models may greatly help understanding cancer biology, especially for the interactions among cancer cells and normal cells in vivo situation . For this purpose the need of tumor - bearing animal models that can be elucidating the behaviour of cancer cel...
The next volume of the international journal of telerehabilitation will be published in fall, 2014 . We cordially invite your submissions by october 1, 2014 and accept original research, case studies, viewpoints, technology reviews, book reviews, and country reports that detail the current status of telerehabilitation ...
Fgm / c is the incomplete or complete removal of female external genital organs for nontherapeutic reasons (1). At least 140 million females today are estimated to have suffered fgm / c (2), and approximately 3 million women, including young females, every year are at risk of undergoing this procedure (3). Who, unicef,...
Schistosomatidae (platyhelminthes: digenea) includes several digenetic endoparasites with complex life cycles, whose developmental stages alternate between intermediate (freshwater gastropods) and definitive hosts (birds, reptiles, fishes, and mammals). Another important feature is the increased longevity (over 5 years...
Clinical studies have demonstrated that increased level of inflammatory parameters related to acute phase reaction such as interleukin-6 or c - reactive protein (crp) predicts unfavorable outcome in ischemic stroke patients (reviewed in). Hyperfibrinogenemia in acute cerebral ischemia is associated with increased risk ...
A man in his eighties with a past medical history notable for 4 primary cutaneous melanomas (all ajcc stage ia or 0), squamous cell skin cancer, and severe actinic damage presented for routine skin cancer surveillance follow - up . On the left dorsal forearm, a new 8 mm bluish nodule was detected during photographicall...
It is increasingly recognized that health workers, especially nurses and nursing technicians, are subject to a variety of health hazards . Several studies have indicated the need to identify, in a critical area such as an icu, the factors causing hazards, as well as strategies to avoid them, so that the health of these...
Bronchogenic cysts are congenital lesions that originate from the tracheobronchial tree in the sixth week of gestation . Their usual site is middle mediastinum, but infrequently these have been reported to present as a subcutaneous swelling or sinus . A 3-year - old healthy male child born to non - consanguineous paren...
Found that serglycin is distinctively expressed in acute myeloid leukemia (aml) relative to lymphoblastic leukemia . Serglycin is also a selective marker distinguishing aml from philadelphia chromosome - negative chronic myeloproliferative disorders . In multiple myeloma cells, serglycin is a secreted protein decorated...
Nonpolio afp case - patients showing signs of acute onset of focal weakness or paralysis characterized as flaccid (reduced muscle tone) and preceded by fever were considered for npev analysis . August 2010 from children <15 years of age who had afp symptoms were analyzed by using a modified world health organization (w...
Proton pump inhibitors (ppis) have been used widely and achieved great benefits in managing acid - related upper gastrointestinal diseases, including gastroesophageal reflux disease (gerd), peptic ulcer disease, helicobacter pylori infection, nonsteroidal anti - inflammatory drug (nsaid)-associated gastric mucosal dama...
It results from invasion of pathogenic microorganisms (bacteria, viruses, or fungi) to the urinary tract system [1, 2]. Incidence of disease in boys and girls has been reported 1% and 3 - 5%, respectively . The disease manifests in three forms; cystitis, pyelonephritis and asymptomatic bacteriuria [1, 2]. Escherichia c...
Despite the development of excellent diagnostic tools, there still remain patients with metastatic cancer in whom the site of the primary tumor cannot be determined; these patients are defined as having cancer of unknown primary (cup) [1, 2]. The prevalence of cup reportedly accounts for approximately 2 - 5% of all can...
On july 1, 2004, the 4 inmates from the california state prison in riverside county were hospitalized with signs and symptoms consistent with clinical botulism, including blurry vision, dysarthria, dysphagia, shortness of breath, and generalized muscle weakness . None had a history of injection drug use and had no need...
The chapel hill consensus conference (chcc) on the nomenclature of systemic vasculitis defined pan or alternatively classic pan as a condition characterized by the necrotizing inflammation of medium - sized or small arteries, without glomerulonephritis or vasculitis in the arterioles, capillaries, or venules . In class...
The human brain is a complex and efficient information system . Learning changes this system as we adapt to information in the environment . Professional musicians comprise a special population for studying learning because they often begin intensive music training early in life and excel in various cognitive tasks, su...
The muscle damage theory of delayed onset muscle soreness (doms) indicates that muscle pain is caused by tiny lacerations of the muscle during strenuous exercise1,2,3, and the muscular spasm theory states that muscle pain induced by exercise causes muscular spasms, which cause local ischemia, inducing secretion of pain...
Sleep disorders have been described in the medical literature since the 19th century.1 obstructive sleep apnea (osa) is a treatable but markedly underdiagnosed condition of frequent breathing pauses during sleep . Osa is defined by recurrent episodes of apnea (complete cessation of airflow) or hypopnea associated with ...
Ischemic stroke is the third leading cause of death worldwide with 5 million annual deaths . Every years approximately 795,000 people experience a stroke and someone dies of stroke in the united states every 3 - 4 minutes . One of the prominent objectives of stroke research has been to investigate factors that could po...
The dimensions of the edentulous residual ridge are not stable because of bone resorption and mucosal changes from muscle dynamics or tissue irritation . Thus, complete an ideal denture base would continuously adapt to the mucosa and thus should be flexible . However, it also has to support the teeth during function an...
The results are gripping hopkins and brett suggest that' the neurocognitive impairments in ards [acute respiratory distress syndrome] survivors are long lasting and likely permanent' . I shall argue that it is difficult to pull apart the diverse factors that might prevent a patient's return to clear thinking . I shall ...
Techniques for directly assessing and quantifying rna by high - throughput sequencing, collectively known as rna - seq, have revealed unexpected complexity and diversity in human transcriptomes . Many previously unknown transcripts that are being detected are low - abundance long intergenic non - coding rnas (lncrnas),...
A 75-year - old caucasian female, awaiting elective laparoscopic cholecystectomy, complained to her general practitioner of persistent cough, dyspnoea and low - grade fever that had lasted for more than one month . She presented to the emergency department, where a chest radiograph showed areas of consolidation in the ...
This study aims to report the expansion of a choroidal rupture site caused by blunt ocular trauma using scanning laser ophthalmoscope - optical coherence tomography . The clinical course of a 15-year - old girl with a traumatic ocular injury after being hit in the eye by an elbow was evaluated . Upon the first examinat...
Studies on major depression, anxiety, schizophrenia, mania, autism, obesity, and drug addiction have implicated the involvement of serotonergic (5-ht) abnormalities in these diseases . Serotonin acts via receptors which were classified into seven families (5-ht17) and at least 14 different subtypes (barnes and sharp, 1...
Prostate cancer is the third most common cancer in man and is the most commonly encountered malignancy in clinical practice . In the us, there were 27,360 deaths attributed to prostate cancer and 192,280 new cases diagnosed in 2009 . About 1 in 6 males develop prostate cancer and 1 in 35 males die of this disease . Whi...
Bilateral salpingo - oophorectomy (bso) causes an abrupt decline in estrogen and acute increase in gonadotropin . Previous studies have shown an increase in the rate of coronary heart disease after bso.1,2 it has also been demonstrated that the risks of vertebral and hip fractures in women who have undergone bso increa...
Chronic obstructive pulmonary disease (copd) is the third leading cause of death in the us, with cigarette smoking being the most important environmental risk factor . Cigarette smoke inhalation alters the expression profile of oxidants and antioxidants in the lungs and produces an enormous oxidant burden . Antioxidant...
Cherubism is a rare disease of autosomal dominant inheritance characterized by painless, frequently symmetrical, enlargement of the jaws as a result of the replacement of bone with fibrous tissue [1 - 16,20,29]. The disease is also called familial fibrous dysplasia of the jaws, but recent genetic investigation has show...
Congenital mirror movement disorder designates involuntary movements on one side of the body that occur as mirror of the intentional movements on the contralateral side . A two - month old male infant was brought to the hospital due to bilateral identical movements of the hands . Except for bilateral involuntary synkin...
After cell fate determination and morphogenesis, neurons continue to differentiate by entering the phase of synapse formation . Most synaptic material required for this process is synthesized in the cell body of neurons and transported to synapses by microtubule (mt)-based molecular motors (fig . Mt - based molecular m...
End - stage renal disease (esrd) has emerged as a major public health problem, with an alarming increase in incidences and a challenge for both developing and developed countries.1 globally, it is estimated that 1.9 million patients are currently receiving renal replacement therapy (rrt), mainly dialysis.2 the number o...
We also describe the ultrasonography (usg), computed tomography (ct), and magnetic resonance imaging (mri) features with surgical and histopathological confirmation . A 32-year - old male patient was referred to the radiology department for ct examination of the face with symptoms of swelling in the left side of nose f...
There is a clear link between age and susceptibility to a wide range of diseases [reviewed in (niccoli and partridge 2012)] and key among the age - related diseases that are rising in incidence is diabetes and metabolic syndrome . Ageing has specific consequences on mammalian physiology, but it also interacts with gene...
However, the use of this method has been limited because the superficial layer of the skin, the stratum corneum, is not sufficiently permeable to allow effective transfer of medication into the bloodstream . To enhance transportion of drugs through the skin, several approaches, including chemical enhancers (johnson et ...
Tumors of the chest wall are uncommon and include benign and malignant diagnoses which can be further classified into those arising from bony structures and those of soft tissue origin . The clinical findings and the radiological appearance of soft tissue chest wall tumors has been previously reported in the literature...
During investigation of physical and genetic interactome of heat shock protein 90 (hsp90) in saccharomyces cerevisiae several putative interacting proteins were identified, among them 2 protein pih1 and tah1 was named after their characteristic . Protein interacting with hsp90 was termed as pih1 (also known as nop17) w...
It is estimated that today more than 347 million people suffer from diabetes mellitus (dm) globally . Diabetic retinopathy (dr), one of the most common complications of dm, accounts for about 5% of world blindness; this represents almost 5 million people in 2002 . Approximately 80% of all patients with dm duration of a...
Over millions of years, eukaryotic organisms evolved fine - tuned metabolic mechanisms for orchestrating the conversion of diverse carbon substrates into cellular energy . These mechanisms include changes in gene transcription, allosteric regulation of metabolic enzymes by fluxing pools of intermediary metabolites, and...
Headache is the most common neurological symptom, but has a low healthcare and public profile, which is associated with under treatment and under recognition, despite being amongst the top ten causes of disability . The arab world covers a large geographical area over the continents of africa and asia with an estimated...
A 49-year - old male presented with an incidentally detected right renal mass on a health examination . The patient had no symptoms or signs associated with the renal mass but presented with mild anemia (hemoglobin, 11.6 g / dl) and elevated alkaline phosphate (170 u / l). An abdominal ct performed in another hospital ...
This study was approved by the ethical committee of the federal university of cear, brazil . All the children and we included 40 h. pylori - positive children (18 females and 22 males) from eight-18 years old with a mean age of 13.2 (standard deviation = 3.2) years . These children had previously participated in h. pyl...
Pulmonary tuberculosis is a common infection worldwide . In iran, particularly in the eastern part, fluctuations in tuberculosis prevalence are seen due to the migration of people from afghanistan . In smear - positive pulmonary tuberculosis, currently, the follow - ups are performed at the end of months 2, 4, and 6 vi...
Uric acid (2,6,8-trihydroxypurine, ua, figure 1), the principal breakdown product of human purine metabolism, is mainly excreted by the kidney . Normally, most of ua produced from the catabolism is reabsorbed into the blood circulation system and then passes through the kidney into urine . When ua in human urine or ser...
Studies on cancer - associated venous thromboembolism (vte) have encompassed a variety of perspectives, including incidence rates, related risk factors, prophylaxis, and treatment, for a range of tumors . Although few prospective studies have investigated the incidence of and risk factors for vte in asian patients, it ...
Once simply considered as the guardians of the central nervous system (cns), microglia have more recently emerged as key players in regulating neuronal network excitability . Indeed, physical and chemical alterations in the extracellular environment promote the synthesis and release of several microglia - derived molec...
Wolff parkinson white (wpw) syndrome is caused by pre - excitation of ventricle due to an abnormal accessory pathway, bundle of kent, between atria and ventricle bypassing atrio - ventricular node . Patients may present with symptoms ranging from mild chest discomfort, palpitation and hypotension to severe cardiopulmon...
Primary prevention efforts for cardiovascular disease (cvd) focus on the identification and modification of 3 established risk factors (hypercholesterolemia, hypertension, and type 2 diabetes mellitus),1 which are associated with substantial longterm risk of cvd . For example, adults with one risk factor at midlife hav...
Thyroid nodules and cancer have long been considered to occur predominantly among women . On the other hand, male gender has been reported to be an important risk factor for the development of the subgroup of well - differentiated thyroid cancers, based on the occurrence of larger tumors, worse prognosis in follicular ...
It is well known that the shape and size of the inorganic nanoparticles have a great influence on their physical properties . In recent years, the synthesis of nanoparticles with well - controlled morphology and size has received lots of interest for their potential applications in nanoscale plasmon photonics, drug del...
The number of the patients with heart failure is increasing in both developed and developing countries, with approximately 1%2% of adults in developed countries experiencing heart failure (2). In iran, the number of these patients is estimated to be about 3,500 out of 100,000 (3). Meanwhile, about 50%55% of the patient...
Antimalarials are frequently used for presumptive treatment of fever especially in malaria endemic regions . In view of the increasing resistance to existing antimalarials, india switched to artemisinin based therapy as first line antimalarial treatment in its national vector borne disease control programme . In 2005, ...
African trypanosomiasis is one of the neglected diseases currently ravaging several countries in the sub - saharan africa . The disease, which affects both humans and animals, is fatal if left untreated . Chemotherapy which forms the major means of controlling the disease scourge is currently faced with many challenges...
After meningitis, brain abscesses represent the second most common intracranial complication of chronic otitis media (com)14), with an associated mortality rate ranging between 7% and 61% in most large series11,14). Roughly 50% of brain abscesses in adults and 25% in children are believed to stem from otogenic infectio...
During free time between clinical procedures, patients performed a spatial learning task on a bedside laptop computer . Our testing protocol is approved by the institutional review boards of thomas jefferson university and the university of california, los angeles . In this task, patients learned the locations of four ...
Mathematical models for assessing drug permeability and predicting in vivo drug release from nanoparticle formulations would be useful both in the design phase and during preclinical testing where avoiding the extensive use of animals would be highly desirable . Such models would facilitate the design of formulations w...
Upper gastrointestinal (ugi) cancers (gastric and esophagus cancer) constitute a major health problem worldwide (1). Although a decreasing incidence of gastric cancer has been observed during the last decades, it remains the fourth most common cancer worldwide and the second leading cause of cancer - related death (2, ...
Cissampelos sympodialis is a plant found in the northeast and southeast regions of brazil and its extract is popularly used in the treatment of both inflammatory and allergic diseases . Studies using the aqueous fraction of the ethanolic extract obtained from its leaves (afl) have confirmed its immunomodulatory effects...
Diabetes is a chronic disease that occurs when the pancreas does not produce enough insulin or when the body cannot effectively use the insulin it produces . Loss of -cell function caused by reduced insulin synthesis and secretion is one of the key events in the pathogenesis of type 2 diabetes . Normal cells can compen...
Nanostructured zno has been the source of great scientific interest, toward both the understanding and exploitation of its intrinsic properties and the performance in optoelectronic applications due to its direct wide band gap of 3.35 ev at 300 k and the high exciton binding energy of 60 mev . Consequently, fabricating...
An implantable cardioverter defibrillator (icd) is indicated for patients who were resuscitated from sudden cardiac death due to fatal ventricular tachyarrhythmias . In the past decade, several studies showed the superiority of an icd over antiarrthythmic drug therapy1)2) and nowadays, icd has proven to be effective in...
Duplicate or redundant publication describes a practice where 2 or more articles that share substantially similar information are published by the same author(s), without clear, visible reference to the previous publication . It is time and resource wasting for the readers, peer reviewers, and editors and unnecessarily...
Kawasaki disease (kd) is a self - limited, systemic vasculitis of unknown etiology that affects the small and medium - sized blood vessels of the body . Occur in children less than 5 years of age, and the incidence is highly varied, ranging from 4 to 216 per 100,000 children less than 5 years of age worldwide . The mos...
Dementia is a multifaceted syndrome that lays claim to a growing burden of global disease: the most recent estimates suggest that there are 44 million affected individuals worldwide and a further 7.7 million new cases annually (1,2). Underpinned by a shifting demographic and associated epidemiological profile worldwide...
We have a limited capacity to process all of the visual information that enters our visual field at any point in time . For this reason, selective attention to salient stimuli is necessary as it helps us decide where to move our eyes next . In this regard, our attentional system enhances the processing of relevant info...
We report a case of a 64 year old caucasian male with a history of kidney transplant, after an aortic valve repair who was recovering in the cardiac critical care unit . A consult was placed to the transplant surgery team on post - operative day four after aortic valve exploration and repair of a paravalvular prostheti...
Feline leukemia virus (felv) is a highly contagious virus that is readily spread among cats in casual close contact, which can include sharing food and water, as well as mutual grooming . Approximately one - third of cats exposed to felv develop progressive viremia and most die of felv - related diseases within 3 years...
During last 10 years, several high throughput and even high output structure determination pipelines (mostly using x - ray diffraction methods) were developed by a number of multi - institutional consortia . They all share the same goal: rapid progress from the cloning of a protein gene to the determination and deposit...
Haemosuccus pancreaticus is a rare and potentially life threatening clinical entity, and is described as bleeding from the ampulla of vater via the pancreatic duct . The syndrome is classically attributed to erosion of the splenic artery aneurysm in to the pancreatic duct or bleeding in to a pseudopancreatic cyst as a ...
Viruses exploit the molecular machinery of the infected host to support their own life cycle and target host defense mechanisms to escape host resistance . This is achieved by establishing a virus - specific protein interaction network that perturbs cell processes, such as dna replication, gene expression, growth and d...
Cz and croscarmellose sodium (ccs) were gift samples from torrent pharma, ahmedabad, india and wockhardt research centre, aurangabad, india respectively . Directly compressible mannitol (pearlitol sd 200), sodium stearyl fumarate (ssf) were generous gifts from strides arco labs, bangalore, india, glenmark ltd ., nashik...
Nontuberculous mycobacterial (ntm) organisms are widely distributed in the environment and the frequency of ntm pulmonary disease has been reported to be increasing (1, 2). Ntm species are divided into slow - growing and rapid - growing species by the runyon classification (2). Representatives of the slow - growing spe...
Pepe) in the containers in the spring of 2002 . A disease suspected as mucor soft rot occurred on cherry tomato (lycopersicon esculentum) in agricultural products wholesale market in jinju . The fungus attacked only dropping fruits in the field or cracks of matured fruits of cherry tomato (fig . The infected parts of c...
Patients with relapsed / refractory (r / r) b - precursor acute lymphoblastic leukemia (all) and patients whose minimal residual disease (mrd) persists during front - line treatment or who become mrd positive following treatment have a poor leukemia - free survival (lfs). Despite improvements in upfront treatment, as t...
Several types of monochromators have been developed for electron microscopy in this decade and are now available as a tool for material characterization . They can reduce the energy spread of incident electrons to milli - electron - volt level . Monochromators can improve a diverse range of electron microscopy techniqu...
(nephropathy, neuropathy, and retinopathy) and macrovascular diseases (atherosclerosis of coronary, cerebral, and peripheral arteries) are prevalent in diabetic patients . Diabetes is associated with polyvascular, accelerated, and diffuse atherosclerotic diseases . In advanced stages, the chances of atherosclerotic pla...