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Cystoid macular edema (cme) is the formation of fluid - filled cystoid spaces between the outer plexiform and inner nuclear layers of the retina, resulting from disruption of the blood - retinal barrier . It is a common complication observed after cataract surgery, with or without other complications . Although the pat... |
Photodynamic therapy (pdt) is treatment with drugs that react to light; the mechanisms of action is based on the science of photochemistry . The effects of pdt are based on the interaction of a tumor - selective photosensitizer and a laser beam of light . A basic photochemical reaction occurs when a sensitizer in an ex... |
Recovery of the gait ability of stroke survivors is an important goal of rehabilitation1 and is known to be influenced by environmental factors (e.g., walking on the ground, climbing stairs, and avoiding obstacles), physical factors (e.g., muscle strength, endurance, and balance), and psychological factors (e.g., judgm... |
Cryptococcosis is a life - threatening fungal infection, caused by cryptococcus (c.) neoformans, an encapsulated yeast . Primary infection develops in the lungs by inhalation and remains asymptomatic in the majority of immunocompetent hosts . T cell - related immunodeficiency, most commonly in association with hiv infe... |
The full - length 569-residue lasv np protein (josiah strain) was expressed and purified as a recombinant mbp fusion protein in e. coli as described in methods . The purified protein exists mainly in two forms, with a majority in trimeric and some in hexameric form . Both forms bind random rnas, which are longer and mo... |
For many generations, marine algae have been extensively used in coastal regions in the far east as food for humans and animals and as organic fertilizers . The high protein, lipid, and vitamin content of marine algae have encouraged their cultivation and use as a food source in many parts of the world . These algae al... |
We present a case of splenic rupture in an adult with complicated malaria in east africa . Despite the rarity of such presentations, this case has been published to remind clinicians about the complications of malaria that should be considered in the differential diagnosis of acute abdomen, even when radiological studi... |
Chitosan is known to be biodegradable, biocompatible, nontoxic, nonallergenic, renewable material . Chitosan is produced commercially by deacetylation of chitin which is the second most abundant polymer after cellulose . Due to its unique polycationic nature, chitosan has been shown to possess antibacterial as well as ... |
Cutaneous pseudolymphomas are a group of benign reactive t- or b - cell lymphoproliferative processes of diverse etiology that simulate cutaneous lymphomas clinically and histologically . The diagnosis and classification of pseudolymphomas is a challenge for the clinical dermatologists and dermatopathologists . Though ... |
During evolution, the stability of genetic material plays a fundamental role in the maintenance of life . The equilibrium between the benefits of changes in the blueprint of life, which facilitates diversity, and the perpetuation of genetic information is fundamental for evolution . In multicellular organisms, this equ... |
Recurrent aphthous stomatitis (ras) is the most common type of ulcerative disease of the oral mucosa, and it affects approximately 20% of the general population . The classic presentation of ras is recurrent, self - limiting ulcers that mainly affect nonkeratinized oral mucosa . A prodromal burning sensation lasting 24... |
Duodenal neuroendocrine tumors (nets) are rare neoplasms that originate from the enterochromaffin cells of the gastroenteropancreatic neuroendocrine system . Duodenal nets account for only 2.6% of nets in the united states,1 although they are being increasingly recognized with the more widespread use of upper gastroint... |
Odontomas are hamartomas of aborted tooth formation, which account for 22% of the odontogenic tumors . Compound odontomas manifest as a regularly shaped, solitary or multiple small tooth - like denticles, where all dental tissues are represented in a structural and more orderly pattern . A complex odontoma presents as ... |
Splenic artery pseudoaneurysms are rare vascular abnormalities typically caused by sequelae of pancreatitis or abdominal trauma, and can lead to fatal bleeding complications if left untreated . The treatment options for splenic artery pseudoaneurysms include transarterial embolization, splenectomy or splenic artery lig... |
Hydroxystilbenes (hereafter referred to as stilbenes) are natural phenolic compounds occurring in a number of plant families including vitaceae, dipterocarpaceae, gnetaceae, pinaceae, poaceae, fabaceae, leguminoseae, and cyperaceae . Although polyphenolic compounds display an enormous chemical diversity, stilbenes seem... |
An 80-year - old woman (weight, 53 kg; height, 154 cm) was scheduled for tkra of the left knee due to degenerative joint disease . Preoperative electrocardiography (ecg) showed normal sinus rhythm and a complete right bundle branch block (fig . We did not perform an echocardiogram, because it was obtained at another ho... |
A retrospective chart review was conducted of patients from september 2006 through september 2010 who presented with an acute central scotoma or defective vision secondary to smh from n - amd . Inclusion criteria for the study included: symptoms of 7 days duration, thick (causing visible elevation of the fovea by slit ... |
We describe a 61 year - old caucasian male who presented to our hospital complaining of sudden onset diplopia which lasted over 24-hour period . He had become aware of double images while working at his computer the previous night . There were no other associated symptoms like orbital pain, headache, neck stiffness, fe... |
Mc was first reported in 1890, but the term used to describe this phenomenon was first coined in 1971 by anderson and smith . Mc has been reported in more than 100 fungal species, and has a considerable number of morphological differences [3, 8]. To understand the morphogenesis of mc, we separated mc morphogenesis into... |
Pancreatic cancer is a common cause of cancer death . Identification of defined patients based on prognostic factors may improve the prediction of survival and selection of therapy . However, pancreatic cancer is difficult to diagnose early, and the prognosis and treatment options depend on many factors, which signific... |
Since it is presently impossible for food producers and processors to ensure a pathogen free food supply, the home food preparer plays an essential role to prevent foodborne illnesses . Some authors (bryan, 1988; medeiros et al ., 2001) reported that only a few types of food handling errors are responsible for the majo... |
To report high resolution spectral domain optical coherence tomography (sd - oct) findings in a case with bilateral photic maculopathy and resultant central scotoma following pterygium excision . A 38-year - old man with a history of pterygium excision complained of visual disturbance and annoying central scotoma in bo... |
An aquatech submersible powerhead (pump) was purchased from walmart (aquatech: moordark, ca). Aquatech offered the least expensive pump per flow rate, retailing at just under $19 and providing a flow of 170 gallons per minute . The pump has two outlet paths, one of them for an aeration tube; we closed that one using hi... |
Oral health is a vital part of general health and is a valuable asset of every individual . Oral diseases are one of the most common of non - communicable diseases affecting varied population . It is an important public health problem owing to the prevalence, socio - economical aspect, expensive treatment, and lack of ... |
Myopia has emerged as a major global public health issue, particularly in east asia 1 . Around 80% or more of young adults have myopia in east asian countries including mainland china, taiwan and korea 2 - 4 . The direct cost of myopia for each school child was estimated to be us $148 5 . Myopia, in particular high myo... |
To fulfill the victorian hepatitis e case definition for surveillance purposes, one must demonstrate seroconversion, a 4-fold rise in paired serum specimens or detect highly reactive igg in a single specimen in the presence of a clinically compatible illness (9). Two commercial tests have been used for hev serologic te... |
In this report, we present our experience and results of treatment of lumbar canal stenosis that involved only fixation of the involved segments of the lumbar spine using two interarticular screws or double insurance screws for each joint . The proposed treatment is based on the hypothesis that vertical instability tha... |
Brodie s abscess, first described by sir benjamin brodie in 1832, is a rare bone lesion variant of subacute osteomyelitis with a presentation that is atypical and usually late [2, 3]. Diagnosis is difficult because the characteristic signs and symptoms of the acute form of the disease are absent . The lesion is caused ... |
Oxidizing agents produced by cell metabolism, chemicals or ionizing radiation can lead to damage of dna and associated diseases (13). One of the most frequent oxidative damages of dna is the oxidation of guanine at position c8 yielding 7,8-dihydro-8-oxoguanine (8oxog) (figure 1a). If not repaired, 8oxog can lead to a g... |
An 82-year - old caucasian male presented to a community ophthalmologist with 6 months of decreased vision in the left eye . Initial workup revealed abnormal fundus findings and the patient was referred to a local retina specialist who diagnosed nonischemic central retinal vein occlusion (crvo) of the left eye, demonst... |
For intra - articular distal radius fractures (ao classification, type b2) with a displaced dorsal fragment, there remains much discussion on the fixation method for the dorsal fragment . To reduce the displaced dorsal fragment, we developed a new technique consisting of fenestration of the volar bone cortex, reduction... |
Erlotinib, a small - molecule egfr tyrosine kinase inhibitor, has been approved by the fda for patients with pancreatic cancer and non - small cell lung cancer . Skin rash is a well - known side effect related with all egfr blocking agents . It has been suggested that rash could be used as a surrogate marker for respon... |
Lung cancer is a very common malignancy with the peculiar characteristic of high aggressivity and lethality, so it has been called the big killer . Pulmonary lobectomy is the operation of choice for the standard treatment of early - stage lung cancer . It encompasses an approach through the pleural cavity and the ligat... |
Congenital adrenal hyperplasia (cah) is characterized by the inability to produce adequate amounts of glucocorticoids and mineralocorticoids, and reciprocal excessive production of androgens [13]. Untreated, cah can result in adrenal crisis attended by circulatory collapse and hypoglycemia [13]. Excessive androgen prod... |
Perhaps no amino acid in the bacterial photosynthetic reaction center (rc; figure 1a) has been scrutinized more than the tyrosine situated near the dimeric bacteriochlorophyll (bchl) primary electron donor (p) and the monomeric bchl initial electron acceptor (ba) on the a - side of the rc . This residue is tyr m208 in ... |
The melting and annealing of dna hairpins are essential in many biological processes such as replication, transcription, recombination, gene expression, and dna transposition for both prokaryotic and eukaryotic systems . Furthermore, hairpins with multiple loops are known to play specific roles in viral replication . A... |
Obsessive - compulsive disorder (ocd) is one of the most common neuropsychiatric disorders, with a lifetime prevalence of 2%3%.13 ocd is characterized by persistent intrusive thoughts (obsessions), repetitive actions (compulsions), and excessive anxiety . A major characteristic of obsessions and compulsions is that the... |
Vascular diseases represent an important problem due to their potential severity and increasing prevalence . Many series of studies, especially those on atherosclerosis, have contributed to reduce the mortality rate of vascular diseases and to improve the patients' quality life . Unfortunately, it is not a case in suba... |
It is well documented that intracranial artery stenosis (icas) has become the most frequent cause of stroke worldwide . Indeed, in asian countries, icas has been found to be the cause for up to half of all stroke cases . Similarly, previous studies in the united states also indicate that icas contributes to a substanti... |
Leishmania parasites maintain a life cycle consisting of a phase in a dipteran insect (sandflies) and a phase in a mammalian host . This can lead to infection of macrophages, in which the parasite thrives inside the hostile environment of the phagolysosomes . Leishmaniasis is one of the most important of the neglected ... |
Small cell carcinoma (scc) is relatively common and accounts for about 20% of lung cancer . Chemotherapy, not resection or radiation, is the sole therapy for scc of the lung, indicating a poor prognosis . Although the majority of scc are located in lungs, the minority (2.54.1%) has been reported to be from extrapulmona... |
A 12-year - old boy presented with painful swelling on his left thigh after being kicked by his friend . Plain radiography revealed a concentric cystic lesion with cortical thinning and ballooning in the mid - portion of the femoral shaft accompanied by a pathologic fracture (fig . The patient underwent curettage of th... |
Colorectal cancer (crc) is highly preventable with screening, yet it remains the third leading cause of cancer death in both men and women . Crc screening is uniformly recommended in men and women as well as blacks and whites over the age of 50 . However, almost half of eligible individuals do not complete crc screenin... |
The world has seen a rapid increase in the incidence of diabetes generally, and type 2 diabetes has become the most common metabolic disease globally . This has been in part due to a growth in obesity, especially excess visceral adiposity, in addition to the associated metabolic syndrome which encompasses insulin resis... |
The first course that will be described is a non - majors course called sex, gender, and the brain (sgb). This course combines three hours of class and three hours of lab per week, for fourteen weeks . It is cross - listed between biology and women s studies, and typically fills with a variety of majors . The course be... |
In recent years direct measurements of cone pigments combined with inferences drawn from examinations of the genes coding for photopigment opsins have provided a greatly enhanced understanding of the distribution and evolution of cone photopigments . The consensus is that four families of genes specify the opsin protei... |
Second to lung cancer in men and breast cancer in women, colorectal carcinoma (crc) has increased in incidence over the past 20 years . About half of the patients undergoing radical resection of crc will develop metastatic disease [1, 2], mostly to the liver (33%) and the lungs (22%). The overall 5-year survival rate o... |
Assessing the potential risk that a substance poses to human health or the environment involves a combined quantitative analysis of both exposure and hazard, including the estimation of associated uncertainties . For decades, the evaluation of toxicological hazards in the context of regulatory risk assessment has relie... |
For more than a century, the fruit fly drosophila has been used to unravel major biological questions . The fruit fly has played crucial roles in deciphering various developmental signaling cascades such as the notch, wingless, and hedgehog pathways . In addition, studies using drosophila have contributed to a wide ran... |
Massive acute pulmonary embolism (pe) remains a life threatening event, associated with significant morbidity and mortality . Conservative treatment of pe includes administration of thrombolytics, however, in hemodynamically unstable patients, emergent surgical embolectomy may be indicated . Hemodynamic instability is ... |
Knee punctures were taken from 26 ra patients and five osteoarthritis (oa) patients . Ra patients (6 male, 20 female) had a mean age of 52 yr (range 3666); their mean disease duration was 6 yr (0.516). Oa patients (1 male, 2 female) had a mean age of 68 (6278); mean disease duration was 8 yr (612). The volume of synovi... |
Emergence of multi - drug resistance (mdr) among enterobacteriaceae is a threat observed in the last two decades . Carbapenems are broad spectrum antibiotics structurally very similar to penicillin but contain a sulphur group at c1 position . Several gram - negative pathogens have become resistant to these by acquiring... |
Total body water (tbw) was measured on two consecutive days using stable, nonradioactive, nontoxic isotopes . For the first measurement of tbw, the participant was given an oral dose of an isotope of oxygen (o), in the form of water (h218o). The subject consumed 1.5 g / kg body weight of 4% h218o via a syringe to minim... |
Acute myeloid leukemia (aml), a hematologic malignancy of the myeloid line of white blood cells in the bone marrow, is the most common leukemia of the adult [1, 2]. Despite major progress in the treatment of aml during the last couple of years different genetic causes result in variable clinical courses of amls and dif... |
The incidence of patent ductus arteriosus (pda) among very low birth weight infants (vlbwis) is reported to be 30% . Its incidence is inversely related to gestational age; depending on which diagnostic criteria is used, pda is estimated to affect up to 80% of infants born at 2425 weeks gestation . Despite the higher in... |
Influenza is responsible for three to five million cases of severe illness and about 250 000 to 500 000 deaths each year worldwide (http://www.who.int/mediacentre/factsheets/fs211/en/index.html). These numbers, together with increased disease awareness and focus on pandemic preparedness, have contributed to the importa... |
In eukaryotic cells, hundreds of molecules are exchanged between the nucleus and the cytoplasm every minute . This process, called nucleocytoplasmic transport, is crucial not only for basic cellular activities but also for regulating various cellular events . Based on the literatures and database information, we can es... |
The coagulation cascade is a complex system, which can be activated by an intrinsic pathway (blood stasis and contact activation) or an extrinsic pathway (exposed tissue after vascular damage). The final common pathway from these two potential stimuli starts with the activation of plasma factor x into activated factor ... |
The human vocal fold can be divided into five different layers: squamous epithelium, lamina propria (superficial, intermediate and deep layers) and the thyroarytenoid muscle . The superficial layer of the lamina propria, also known as reinke's space, plays a relevant role in production and quality of the voice, since i... |
Radiofrequency (rf) radiation has long been used for different types of information exchange . Mobile phones which are low power, single channel two - way radios, emit signals via electromagnetic waves . Widespread use and increased popularity of these modern communication devices have caused a growing public concern a... |
Density of breast parenchyma in mammography is presently a feature recognized as one of the risk factors for breast cancer [13]. Relative risk for breast cancer in high density mammograms is 2- to 6-fold higher than in low density ones [1, 2, 4]. Among factors recognized as potentially capable of influencing mammograph... |
Mosquitoes have attracted considerable attention worldwide being the most prevalent vectors of several lethal diseases, malaria, filariasis, chikungunya, yellow fever, dengue, and encephalitis, accounting for enormous mortality and morbidity . Since last few years, dengue fever has become the major public - health conc... |
More than 1 out of 4 donor - recipient couples are incompatible, because of either blood type abo incompatibility or a positive crossmatch . Worldwide, alternative donation programs were developed to enable these couples to pursue donation and transplantation . In kidney - exchange donation, a match is sought between 2... |
Fifteen patients with type 2 diabetes receiving stable sulfonylurea and/or metformin treatment were recruited for study participation . Patients were excluded if they had been treated with insulin, peroxisome proliferator activated receptor- agonists, glinides, or glucosidase inhibitors within the last 4 weeks before s... |
To study about the utility of goniometry in screening for limited joint mobility (ljm) in patients attending a secondary level diabetic clinic . Randomly selected data of 100 patients attending a secondary level diabetic clinic without any complications were used . Range of movement around the ankle joint and 1 metatar... |
Positron emission tomography (pet) is a functional imaging modality to observe the physiological processes in the body . To conduct a pet scan, positron - emitting radioisotopes, as a tracer, when a positron encounters and annihilates an electron, it emits two gamma rays in reverse directions which will be sensed at tw... |
Korean ginseng (the root of panax ginseng c.a . Meyer) is a representative herbal which is ethnopharmacologically well known in east asian countries, including korea, china, and japan for about 2,000 years . This plant is indeed widely used as a supplementary herbal medicine for treating numerous diseases such as cance... |
Malaria is a major parasitic disease with high mortality and morbidity, especially in the sub - saharan africa, latin america, and asia . About 3 billion people worldwide are exposed annually, with 1.2 billion at high risk, and some 200 million developed symptomatic malaria . This disease is caused by malarial protozoa... |
Tuberculum sellae (ts) meningiomas, a member of a group called parasellar meningiomas, grow in the subchiasmal area that can compress the optic nerves . Neurosurgeons have reported that ts meningiomas have a high tendency to extend into the optic canal regardless of their size.15 mahmoud et al reported the tumor extend... |
Glucan particles (gps), prepared from the walls of saccharomyces cerevisiae cells, are composed primarily of -1,3-d - glucans (g) [1, 2]. These are recognized as a fungal cell wall pathogen - associated molecular pattern (pamp) and gps serve as an effective adjuvant for igg antibody production when admixed with free an... |
Saliva lacks the drama of blood, the sincerity of sweat and the emotional appeal of tears . Despite the absence of charisma, practitioners are finding that saliva provides an easily available, non - invasive diagnostic medium for a rapidly widening range of diseases and clinical situations . In the oral cavity, protein... |
Hemoptysis is one of the most common symptoms in patients with respiratory diseases, when massive, has a mortality rate of more than 50% . Therefore, significant or life - threatening hemoptysis calls for quick treatment to stop bleeding . In the past, the control of hemoptysis had been obtained using surgical methods ... |
Although prevalent at all ages, in india it predominantly occurs during fourth to fifth decade of life . Patients with pulmonary disease, complain of nonproductive cough, dyspnea, chest pain, and wheezing . Diagnosis of pulmonary sarcoidosis relies on the presence of noncaseating granulomas on histopathological specime... |
Vector - borne diseases constitute a large percentage of emerging infectious diseases in both human and animal populations.1 lyme disease, a spirochetal infection transmitted by the blacklegged ixodes tick, is the most common tick - borne disease in the united states . In recent years, a growing number of additional pa... |
Rna localization is a widespread mechanism that targets mrnas to regions of the cell, where the proteins are required . Restricting proteins to spatially confined areas results in compartmentalization of the cell and can be achieved either by specific translocation of the protein or the accumulation of the mrna at a sp... |
Pancreatic cancer is the fourth most common cause of cancer - related death in the us . It is predicted that, in 2014, pancreatic cancer will account for approximately 7% (more than 39,500 cases) of all cancer deaths in the us, with more than 46,000 new cases being anticipated . Prognosis is particularly poor, with a 5... |
We have undertaken a proteomic analysis of chromatin passing through interphase of the cell cycle in xenopus egg extract . The abundance of proteins associated with chromatin at different times was assessed by liquid chromatography - tandem mass spectrometry (lc - ms / ms). The behavior of known proteins was as expecte... |
At present in the medical field, the biggest achievement of the human beings is western medicine and traditional chinese medicine (tcm). With a history of 2000 to 3000 years herbal medicines have gained increasing attention worldwide for the treatment of chronic diseases because of their effectiveness and small side ef... |
Matsuba and shimamura s report on the exercise physiology and performance testing of racehorses (fig . 1fig . This report was a large book of 294 pages (b5 size) consisting of 2 parts; the first part was entitled exercise physiology of the racehorse, and the second part was entitled performance testing of the racehorse... |
Protein structures are stabilized by numerous non - covalent interactions, e.g. Hydrophobic, hydrogen bonding, electrostatic and van der waals interactions (1,2). Hydrophobic interactions are believed to be the driving force behind protein folding and stability (3). The cooperative, non - covalent and long - range inte... |
Micrornas or mirnas have been a subject of significant research work since the discovery of lin-4 in the early 1990s, underscoring the importance of posttranscriptional gene regulation in cis and trans . Mirnas are a subset of endogenously - initiated, single - stranded noncoding rna guide molecules, traceable in organ... |
Extrusion of long middle segment of radius following open segmental fracture both bone forearm and dislocation of ipsilateral elbow is a very rare injury . The surgical options in such cases include secondary autogenous fibular gap grafting or leaving a single bone forearm . We hereby report a case of extruded middle s... |
Starting in june 2005, several players of a dutch soccer team, consisting of 35 members, noted soft - tissue infections . In october 2005, the municipal health service received a report of a patient, a member of this soccer team, who had been hospitalized for an abscess resulting from mrsa . Other members of the team h... |
Sipunculans are a phylum of nonsegmented peanut - shaped marine worms that lack a true circulatory system . Recent molecular phylogenetic analyses suggest a close relationship between sipuncula and the phylum annelida, particularly with the major group polychaeta that includes mostly marine worms [24]. These worms have... |
The aapm high energy brachytherapy source dosimetry working group (hebd - wg) recommends that this dataset must be based upon at least one experimental study and at least one monte carlo (mc) study of the model's source dosimetric parameters . For conventionally encapsulated sources similar in design to existing or pre... |
Rugby union is a field based team sport, requiring repeated bouts of moderate to high intensity running and activity separated by low intensity running or walking (1, 3, 15). A rugby union match involves two teams of 15 athletes competing in two 40-min halves . Players are separated into positional groups with forwards... |
In 1998, the who, world bank, undp and unicef conceived and partnered to create the roll back malaria movement, with the welcome and necessary goal of halving malaria deaths by 2010 the first major effort against the disease in four decades . The need for such an effort is abundantly clear: malaria places a huge burden... |
The voltage - gated calcium channels (vgccs) are regulated by kinases that are activated by second messenger pathways [14]. The dihydropyridine - sensitive vgcc, known as the l - type channel or cav1.2, is modulated by protein kinase a (pka) and protein kinase c (pkc). The -adrenergic receptor activates camp - dependen... |
It is characterized by a complex of neuropathological, biochemical, and behavioral symptoms, that gradually impair memory and the ability to learn, carry out daily activities and behavior . In particular, ibotenic acid - induced lesions of the nbm in rats produce impairment in acquisition and retention phase of passive... |
The classification and functional role of the human accessory nerve has been a topic of interest among anatomists dating back to sir thomas willis . Contemporary anatomical texts universally describe the accessory nerve as having two separate components, one from the spinal cord and the other from the brainstem . The s... |
Bladder cancer represents the ninth most common cancer worldwide and the most common malignancy of the urinary tract . Approximately 75%-85% of patients present with nonmuscle invasive bladder cancer (nmibc), for which transurethral resection of bladder tumour (turbt) remains the standard first - line treatment . Manag... |
Was introduced for two species described from tropical and subtropical habitats in africa and australia: a. gelatinosporus (j.w . (2000) mainly on the basis of spore characters (prominent spines on the spore surface within an inflated utricle) and a pink to brown, gelatinized gleba, while hysterangium is characterized ... |
The pharmacists responsibilities have developed from dispensing functions to providing various new professional services . The world health organization (who) has described the role of a pharmacist as a compassionate caregiver, decision maker, active communicator, lifelong learner, good manager, a teacher, and a resear... |
We conducted this study at the microbiology laboratory, mahosot hospital, vientiane, laos, the only microbiology laboratory in vientiane with a routine, accessible hemoculture service for sepsis diagnosis (4,14). Study patients provided written informed consent; ethical approval was granted by the oxford tropical resea... |
Chronic thromboembolic pulmonary hypertension (cteph) is an important cause of severe pulmonary hypertension resulting in significant morbidity and mortality . As it is a potentially curable cause of pulmonary hypertension, its accurate diagnosis is vital . Research on the development of new surgical approaches is esse... |
Metabolic syndrome (mets) is recognized as the clustering risk factors of obesity, insulin resistance, dyslipidemia and hypertension associated with the subsequent development of cardiovascular disease and type 2 diabetes . In addition to adults, the number of children and adolescents affected by mets is increasing . T... |
Recognition of the impact of ventilator - induced lung injury on morbidity and mortality in patients with acute respiratory distress syndrome (ards) has led to an ongoing search for ventilation strategies that limit further damage to the already injured lung . In this issue of critical care, bollen and colleagues prese... |
Craniopharyngioma is the most common non - neural brain tumor derived from pituitary gland embryonic tissue; it occurs primarily in children but also in adults, with an incidence of approximately 2/100 000 . Due to its sensitive sellar / suprasellar location and ability to form large cysts, acp often exhibits locally a... |
The risk of secondary malignancies associated with radiation treatment for cancer patients is an area of controversy in clinical radiation oncology . While the prevalence of second malignancies after radiotherapy for pediatric and young adult populations is well established as one of the significant long - term sequela... |
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