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Hepatitis c virus (hcv) is one of the major causes of chronic liver disease in the world . More importantly, many of those patients with chronic hepatitis c eventually develop cirrhosis and hepatocellular carcinoma . Following infection with hcv, only about 15% of patients can clear the virus, while 6080% of patients d... |
Funding for travel or speaker honoraria: (1) istanbul ms days, novartis pharmaceuticals, speaker honoraria payment to mayo clinic . No personal compensation . (2) invited professor program, biogen - boston, speaker honoraria payment to mayo clinic . No personal compensation . Other activities: grant review for the nati... |
This open, randomized controlled trial recruited diabetes hamilton registrants between june 2005 and november 2008 . People aged 40 years with type 2 diabetes of at least 1 year duration and whose a1c was 7% were included . Individuals who were pregnant, institutionalized, living with another study participant, or resi... |
Study participants were drawn from the women's health study (whs), a completed randomized, double - blinded, placebo - controlled trial of low - dose aspirin and vitamin e in the primary prevention of cardiovascular disease (cvd) and cancer in women (1113). Whs participants were apparently healthy female health care pr... |
The symposium is conducted annually by the angelman treatment and research institute, a part of the angelman syndrome foundation (www.angelman.org). The theme for this year's symposium was the neuroscience of ube3a from genes to behavior . The program consisted of invited speakers and other presentations and was attend... |
High - resolution peripheral quantitative computed tomography (hr - pqct) is a novel imaging modality that noninvasively assesses trabecular and cortical bone microstructure at the distal radius and tibia [1, 2]. Although areal bone mineral density (abmd), as assessed by dual - energy x - ray absorptiometry (dxa), rema... |
The sequential deletion method and other biological and biochemical experiments are generally used to locate the functional domain of a protein . For example, a previous study (1) used the sequential deletion method accompanied by manual pcr primers design to generate the n - terminal truncated mutants of different len... |
Anti - glomerular basement membrane (gbm) antibody disease is a prototypical autoimmune disease characterized by pulmonary hemorrhage and crescentic necrotizing glomerular disease as a result of antibodies targeting the non - collagenous 1 domain of the 3 subunit of type 4 collagen [3(iv)nc1]. The disease course is usu... |
Nucleotides stored in the cells not only serve as substrates for nucleic acid biosynthesis but also participate in the energy metabolism and signal transduction . Nitric oxide (no) is a gaseous free radical that is synthesized by nitric oxide synthases (noss). No plays important roles in the regulation of diverse physi... |
Globally, noncommunicable diseases (ncds), mainly cancer, cardiovascular diseases (cvd), chronic obstructive pulmonary diseases (copd), and diabetes mellitus (dm), are the most important causes of deaths and disability - adjusted life years (dalys). As of 2010, 65% of total deaths in the world were attributable to ncds... |
To enable a broadscale screening and protein profiling for the potential identification of novel biomarker candidates associated with dili, we here set out an explorative affinity proteomics strategy . An initial nontargeted discovery screening that encompassed 4594 antibodies targeting 3450 unique proteins, representi... |
Anorectal melanoma is associated with an extremely poor prognosis regardless of the aggressiveness of surgical therapy; it is commonly incurable at presentation, with many patients developing systemic metastasis within a year after diagnosis . However, reports have noted that long - term survival was seen only in patie... |
Secondary data analysis is analysis of data that was collected by someone else for another primary purpose . Increasingly, generalist researchers start their careers conducting analyses of existing datasets, and some continue to make this the focus of their career . Using secondary data enables one to conduct studies o... |
The genus listeria is composed of 17 species, including two that are recognized pathogens . Of these, l. monocytogenes is considered as the only human pathogen causing listeriosis, a highly lethal opportunistic infection caused by ingestion of contaminated food . The second pathogenic species is l. ivanovii, which most... |
Single coronary artery (sca) is a rare congenital anomaly of the coronary arteries arising from a single coronary ostium1). The clinical significance of sca is not clear, and it is generally considered to be a benign entity . There are some case reports of sca in adults, but there are a few such reported cases in child... |
Ht affects about one - fifth of adult nigerians. [14] it is a risk factor for erectile dysfunction (ed) in men . Many studies have reported a higher prevalence of ed in hypertensive induviduals compared with normotensive individuals. [57] ed is defined as the persistent inability to achieve and/or maintained penile ere... |
Even though the quantity of brain tissue accounts for only 23% of the total body weight, it requires 2025% of the total oxygen supply . Because of the limited oxygen and glucose reserves, brain tissue is susceptible to hypoxic - ischemic injury young and middle - aged patients are a high - risk population for traumatic... |
Solitary fibrous tumors (sfts) are rare mesenchymal neoplasms of fibroblastic origin, most commonly found in the pleura . In fact, they are ubiquitous neoplasms, and non - serosal extrathoracic locations have been reported during the last 2 decades, including intra - abdominal cases . Given the rarity of these tumors, ... |
Plasmacytoid urothelial carcinoma is a rare malignant neoplasm in the urinary bladder recognized by recent who classification of urothelial carcinoma . It is an aggressive variant associated with poor prognosis that presents at an advanced clinical stage . Limited data is available about the pathological, immunohistoch... |
Fabry disease (fd; omim 301500) is a rare x - linked lysosomal storage disorder caused by the deficiency of the lysosomal enzyme -galactosidase a (-gal a; ec 3.2.1.22) which is encoded by the gla gene (omim 300644, refseq nm_000169.2). Phenotypic expression of fd is highly variable, ranging from a milder phenotype with... |
The mitochondrial genomes of angiosperms exhibit a diverse array of features that contribute to increased genomic complexity, including numerous genes and introns, a large amount of intergenic and repetitive dna, and abundant cytidine - to - uridine (c - to - u) rna editing (knoop 2012; mower et al . For example, the 7... |
The history of microbiological research has been dominated by investigations of the agents of human infectious disease . Motivated by the desire to culture, characterize, and understand the pathogenicity mechanisms of these organisms, several centuries of microbiological research culminated in a broad range of antimicr... |
In this paper, we will try to highlight the importance of various investigations and their crucial role in identifying whether the defect is structural or functional . Subsequently, although all ophthalmic signs resolved, she complained of decreased vision in her left eye . Initial ophthalmic injury was detected by opt... |
Acute - phase response is a set of immediate host inflammatory reactions that counteract challenges, such as tissue injury, infection, and trauma . Acute - phase proteins, including c - reactive protein (crp) and serum amyloid a (saa), are primarily produced by hepatocytes and chiefly induced by the proinflammatory cyt... |
Urticaria represents a transient edema within the dermis; the individual urticarial lesions characteristically clear within hours . It is a vascular reaction of the skin, triggered by many known as well as unknown factors that result in liberation of vasoactive substances such as histamine, prostaglandins, and kinins .... |
Tsetse flies are large biting and blood - feeding flies of great economic, veterinary, and medical importance, due to their ability to transmit african animal and human trypanosomoses . Tsetse - transmitted trypanosomoses occur in 38 sub - saharan african countries with averages of 15,000 human cases and one million ca... |
Membrane depolarization elicited outward current through inward rectifier k channels exhibits profound relaxation . Consequently, with identical k concentrations on both sides of the membrane the steady - state outward macroscopic current at positive membrane voltages is much smaller than the inward current at the corr... |
Cervical intraepithelial neoplasia (cin) is a premalignant disease, often leading to invasive cervical cancer . It is widely known that cin is caused by an infection with high - risk human papillomavirus (hpv) types [3, 4]. Interestingly, most hpv infections are transient and do not lead to cin . Genetic, immunologic, ... |
It is transmitted by infected female anopheline mosquitoes when they feed on humans for their oviposition and is responsible for millions of deaths every year around the world (1). Malaria as on today is among the major infectious diseases causing considerable deaths and can be assumed as prime etiological factor of sl... |
Large - scale programs to provide anti retroviral therapy (art) have expanded to combat the epidemic of hiv / aids in india which is third among the populations of hiv - positive cases in the world . However, the expansion art programs have also brought challenges . Successful implementation of an art program hinges on... |
Levetiracetam is an anti - epileptic drug used for the treatment of partial and generalized seizures . We report the case of a 69-year - old woman with previously normal renal function who developed acute granulomatous interstitial nephritis (gin) requiring dialysis following levetiracetam consumption . A 69-year - old... |
" man is a creature composed of countless millions of cells: a microbe is composed of only one, yet throughout the ages the two have been in ceaseless conflict " septic shock remains a common cause of death in intensive care units worldwide and presents the clinician with a variety of management problems . The survivin... |
Aging is currently perceived as an ongoing physiological process that intertwines the patho - biological mechanisms of a diseased state, influencing the development of a clinically evident morbidity . The field of cardiovascular disease is thus oriented to consider the aging process as the determinant of a priori struc... |
A number of studies over the last 15 years have provided converging evidence showing that dyslexic readers of languages with orthographies more regular than english suffer from a pervasive and persistent reading speed deficit, but much less from the reading accuracy problem which is characteristic for dyslexic children... |
Community acquired pneumonia (cap) is one of the main concerns of health services which only causes to 1.7 million cases of hospitalization annually in the united states (1, 2). It is one of the most common infectious diseases and important causes of mortality and morbidity in worldwide (3). Streptococcus pneumonia, he... |
Metaplastic breast cancer (mpbc) is an extremely rare breast cancer subtype constituting 0.25% to 1% of all breast cancers . Histopathologically, mpbc is characterized by a heterogeneous phenotype, most commonly with epithelial and mesenchymal components . Mpbc is typically associated with rapid metastasis and poor sur... |
Epstein - barr virus (ebv) and cytomegalovirus (cmv) are members of the herpesvirus family . Co - infection with these two viruses occurs occasionally in children, but co - reactivation of these viruses has not been reported . Ebv is a double - stranded dna herpesvirus that infects and persists in> 90% of humans worldw... |
Alzheimer's disease (ad) is a neurodegenerative disorder that will affect 15 million people in usa alone in the next ten years [1, 2]. The most common form of the disease is the late onset form (load) that affects people older than 65 . Load is caused by a complex interaction of risk factors including age, genetics, an... |
It has been documented that pregnancy is a unique immunological state with both immune response and tolerance against fetus antigens (1). Previous studies demonstrated that the imbalanced immune responses against fetus antigens can result in abnormality in pregnancy . Cytokines as important immune molecules, play cruci... |
Chemotherapy - induced nausea and vomiting (cinv) is one of the most unpleasant side effects for patients receiving chemotherapy . It can have a significant effect on a patient's qualify of lifeand prevent continuation of chemotherapy . The incidence and severity of cinv are affected by diverse factors, including the s... |
As a service to our authors and readers, this journal provides supporting information supplied by the authors . Such materials are peer reviewed and may be reorganized for online delivery, but are not copyedited or typeset . Technical support issues arising from supporting information (other than missing files) should ... |
Body weight and body mass index (bmi) are independent risk factors for mortality in chronic obstructive pulmonary disease (copd) patients [1, 2]. We researched the relationships between possible nutritional parameters (haemoglobin levels, serum albumin, blood urea nitrogen, creatinine, cholesterol, triglycerides, creat... |
Therefore, the main challenge for commercial plasma collectors in the us is to apply procedures that will safeguard the quality and safety of the product . In many other countries, however, nonremunerated plasma donation is the usual practice . This means that specific interventions not based on monetary incentives are... |
Ductal carcinoma is the most common exocrine tumor of the pancreas and is subdivided into adenocarcinoma and squamous cell carcinoma . Adenocarcinoma, the most common subtype, comprises 80% of all malignant tumors of the pancreas,1,2 while primary squamous cell carcinoma is an extremely rare subtype of ductal carcinoma... |
First generation antipsychotics along with amisulpride, risperidone, paliperidone, and zotepine have been consistently reported to be associated with the high rates of hyperprolactinemia and termed as prolactin - raising, whereas clozapine, olanzapine, quetiapine, ziprasidone, and aripiprazole, which have a more favora... |
The functions of the brain and other body system organs are strongly dependent on proper cardiac performance . Our daily life appropriately emphasizes the strong connections between the heart, emotional reactions and social functions . Therefore, the appearance of normal emotional reactions such as shock, fear, anger, ... |
Anesthesia utilized was either standard peribulbar block or general anesthesia (propofol and nitrous oxide). One eye was randomized (using an unbiased coin) to standard paralimbal strabismus surgery (spss) while the other automatically qualified for miss . After separating the lids with universal eye speculum, a 5 - 0 ... |
Chronic bronchitis is estimated to affect between 3.7% and 6.8% of the population in europe (ball and make 1998), and prevalence increases with age (mcguire et al 2001). Patients with chronic bronchitis are predisposed to recurrent attacks of bronchial inflammation termed acute exacerbations of chronic bronchitis (aecb... |
Periodontitis is an inflammatory disease of the periodontium which elicits an immune response resulting in loss of supporting structures of the teeth . It is independent of various ethnic groups and may be present in children to the elderly . The usual modes of treatment for periodontitis include informing the patient ... |
The world health organization defines suicide act as the injury with varying degrees of lethal intent and that suicide may be defined as a suicidal act with fatal outcome . Deliberate self - harm is a major issue in the health care all over the world . Many factors including biological, socio - cultural, and personalit... |
If untreated, it can lead to pain and discomfort and finally loss of teeth . The disease is not self - limiting and without adequate intervention, the process can continue until the tooth is destroyed . The term caries denotes both the disease process and its consequences, that is, the damage caused by the disease proc... |
Endoscopic submucosal dissection (esd) was introduced for treating early gastric cancer with a minimal risk of regional lymph node and distant metastases 1 . Esd is currently performed worldwide because neoplasms can be resected en bloc, and a detailed pathological assessment of resected specimens can be performed 1 2 ... |
Hormonal disorders of female reproductive system is comprised of a number of problems resulting from aberrant dysfunction of hypo - thalamic - pituitary - ovarian axis . Proper evaluation of these disorders involves a multidimensional diagnostic approach, with a pivotal contribution from clinical laboratories (1). Meas... |
There are only four reported cases in the medical literature describing typical bronchial carcinoids metastasizing to the brain . Little is known about the pathogenesis and presentation of this disease due to the very small patient population . A 67-year - old hispanic female presented to our hospital with a three - we... |
The zebov makona strain seed stock originated from serum from a fatal case during the 2014 outbreak in gukdou, guinea (zebov isolate homo sapiens - wt / gin/2014/ makona - gueckedou - c07, accession number kj660347.2) and was passaged twice in authenticated vero e6 cells obtained from atcc (atcc, crl-1586) [11, 12]. Si... |
The term hemophagocytosis describes the pathologic finding of activated macrophages, engulfing erythrocytes, leukocytes, platelets, and their precursor cells . Hlh is an unusual syndrome characterized by fever, splenomegaly, jaundice, and the pathologic finding of hemophagocytosis (phagocytosis by macrophages of erythr... |
Over 160 million people worldwide are chronically infected with the hcv virus . Besides the liver related complications of hcv infection such as liver cirrhosis and hepatocellular carcinoma, chronic infection is associated in several studies with extrahepatic disorders, including metabolic derangements . Though not man... |
Crisis services are now a well - established part of the mental health systems in north america.1 these programs have been found to be successful in improving access to mental health system for those with acute emotional or mental health problems and to help persons deal with a crisis . Crisis services are also a cost ... |
Details of the patient population, along with inclusion and exclusion criteria, have been previously described . In brief, patients 18 years of age with active up or ups extending 5 cm, but no further than 40 cm, from the anal verge were eligible for enrollment in the studies (clinicaltrials.gov: nct01008410 and nct010... |
This study was conducted in accordance with a protocol approved by an institutional animal care and use committee of the national institutes of health . All laboratory work with potentially infectious materials was conducted in a biosafety level facility at the rocky mountain laboratories (division of intramural resear... |
Early and accurate assessment of the thoracolumbar spine is an important aspect of trauma reception and resuscitation . Between 19% and 50% of fractures may have associated neurological damage to the spinal cord.1 missed or delayed diagnosis can lead to a multitude of problems including long - term pain, reduced qualit... |
The presence of <103 spermatozoa / ml in seminal fluid after centrifugation is called cryptozoospermia that none are seen in initial evaluation (1). Patients with cryptozoospermia also suffer from transient azoospermia, which means that only a few mature spermatozoa may be found in their ejaculate, and hence are infert... |
External ventricular drainage (evd) is an important neuro - surgical procedure performing under emergent conditions . The ideal target for ventricular placement is usually within the ipsilateral frontal horn just anterior to the monro foramen2). Even though the freehand technique using superficial anatomical landmarks ... |
Olive flounder, paralichthys olivaceus has a flattened oval body, mainly occurs at the benthos in water depths of 10200 m, and is widely distributed in korea and east asia (han et al ., 2007). It is the most important cultured fish in korea, with approximately 40,922 tons of this species having been produced in 2012 (p... |
The hepatitis b virus (hbv), which belongs to the hepadnavirus family, is a small circular dna virus containing a nucleocapsid and an envelope . Hbv nucleocapsid contains a relatively small and incompletely double stranded 3.2 kb dna genome, viral polymerase and core protein . Its envelope is composed of viral surface ... |
Acute rejection, observed after renal transplantation, has a significant impact for long - term renal allograft survival . Even though its incidence was reduced by new immunosuppressive drugs, it remains a major problem after renal transplantation . Acute rejection is a cell - mediated immune response that is initiated... |
The nhs was started in 1976 when 121,700 married female registered nurses aged 3055 years received a questionnaire on health status and potential risk factors for major chronic diseases . Ever since, participants were sent questionnaires biennially and the response rates have been 90% (8). The nhs was approved by the i... |
Penile squamous cell carcinoma (scc) is a rare but challenging urological tumour with a potentially devastating course of disease . Only a few studies with larger scale patient cohorts have been published due to the low prevalence . The heterogeneous clinical appearance and different diagnostic and therapeutic strategi... |
As surgeons gain more experience and instrumentation technology advances, more challenging procedures are attempted . Acute and chronic inflammation, fistulization, and abscesses make dissection and mobilization difficult . In 1995, we published our experience with 25 patients and demonstrated that laparoscopic - assis... |
Currently, complete surgical resection represents the only curative treatment for lung cancer1 . However, the majority of lung cancer survivors who undergo lung resection experience pulmonary complications; one - third of these patients report dyspnea, and one - fifth suffer from severely diminished pulmonary function,... |
Chronic obstructive pulmonary disease (copd) is a common disease and a major cause of death worldwide . It is the fourth main cause of death behind cardiac disease, cancer, and cerebrovascular disease in the united states, with a disease - related death incidence of 43.2 per 100,000 population . The death rate due to o... |
There is an increasing concern amongst the women and girls about the appearance of their external genitalia . Many women and adolescent girls present with labia hypertrophy . A young girl presenting with labia hypertrophy is quite unusual . A child with severe hypertrophy of bilateral labia minora patient a, youngest o... |
Living donor kidney transplantation is the treatment of choice for patients with end - stage renal failure for several reasons . The transplant is performed when the donor and the recipient are in optimum medical condition and at a time that is convenient for them and for their families . Moreover, recipients of living... |
Mycobacterium abscessus is the most pathogenic and chemotherapy - resistant rapidly growing mycobacteria (rgm). It accounts for 80% of lung disease caused by rgm and is the second most common rgm species present in extrapulmonary disease (following m. fortuitum) (1 - 4). M. abscessus is resistant to all antituberculosi... |
The tight link between the innate and adaptive immune systems is governed by signaling molecules such as cytokines, transcription factors, and several innate receptors . Cytokines significantly modulate the inflammatory process, which plays an important protective role in innate immunity . Interleukin-10 (il-10), initi... |
Adipose tissue functions as a repository for long - term energy storage and as a critical regulator of energy balance, satiety, glucose metabolism, and other physiological processes . White adipose tissue (wat) stores and releases fatty acids and glycerol in response to the energetic needs of the organism, whereas brow... |
There is a large discrepancy between the supply and demand of surgical services in the developing world, especially for nations in sub - saharan africa . In 2008, of the estimated 235 million surgical procedures performed annually, only 3.5% was performed in developing countries . This inequality also holds true in the... |
The most commonly reported types of seizures are complex partial seizures and tonic - clonic seizures [4, 5], even though eeg documentation of such seizures have been sparse . Status epilepticus has also been rarely reported . Here, we report two patients with hereditary coproporphyria (hcp) who presented with status e... |
Both interstitial granulomatous dermatitis (igd) and palisaded neutrophilic granulomatous dermatitis (pngd) are rare disorders typically associated with systemic autoimmune conditions . They probably represent different aspects of a disease spectrum encompassing the concept of autoimmunity - related granulomatous derma... |
Treadmill walking gait analyses are frequently conducted due to their ease of collecting multiple strides of data, minimal space required and ability to finely control speed . The question of whether a treadmill (tm) walking gait replicates an overground (og) walking gait on a level surface has been extensively studied... |
Abnormal variation of the posterior corneal curvature may occur in two forms: the generalized posterior keratoconus, characterized by an regular increase of the curvature of the entire posterior corneal surface has, and the circumscribed posterior keratoconus, in which a localized paracentral or central posterior corne... |
Endothelial and epithelial monolayers and their associated basement membranes form physical and functional barriers separating distinct tissue compartments . These barriers are frequently breached, e.g., by immune cells as part of their homeostatic or inflammatory trafficking, by tumor cells during metastatic spread, o... |
Restoring posterior teeth with resin - based composite materials continues to gain popularity among clinicians, and the demand for such aesthetic restorations is increasing . Indeed, the most common aesthetic alternative to dental amalgam is resin composite . Long - term studies have shown that the bond strength of res... |
Goodpasture s syndrome or anti - glomerular basal membrane (anti - gbm) disease is a rare disorder first described by earnest goodpasture in 1919 . The disorder is characterized by formation of antibodies against non - collagenous domain of the 3 chain of type iv collagen of the gbm . Combination of rapidly progressive... |
All reagents and solvents were obtained from commercial suppliers and were used as received without further purification . Nmr spectra were recorded on a 400 mhz (h), 100 mhz (c) nmr spectrometer at 25 c . Chemical shifts () are reported in parts per million referenced to the nmr solvent residual peak, and coupling con... |
Burn injury is a major global problem with special importance in the east mediterranean region, including iran . In iran, burn injuries have high incidence and mortality rate, in that at least eight people die from burn every day . It is ranked as the third cause of mortality after traffic accidents and trauma . Despit... |
Sexual dysfunction in women is characterized by persistent and recurrent problems in sexual response or desire, which cause affliction and affect their relationship with their partner.1,2 sexual dysfunctions may occur at any age and affect roughly 40% of women at some point in their lifetime, with 12% of women reportin... |
The glutathione - s - transferase (gst) proteins represent an extended family with high diversity depending on the organism [13]. These enzymes are usually able to conjugate glutathione (gsh) to hydrophobic molecules and thus are involved in biotransformation pathways . The addition of gsh onto molecules, previously ox... |
The worldwide population is aging and consequently the incidence of osteoporosis is increasing . This systemic, metabolic disease is most distressing to patients and healthcare providers in the occurrence of osteoporotic fractures of the hip and spine and occasionally, various other sites throughout the skeleton . Oste... |
Orthopaedic surgeons may find it difficult to get rotationally anatomical reduction of a shaft fracture of the humerus . If rotational control is not achieved, nonunion is more likely to occur.2 in addition, malrotation of the humeral component of total elbow replacement influences laxity and causes maltracking.3 the r... |
The vein of marshall (vom) is an embryonic remnant of the left superior vena cava.1) the ligament of marshall (lom), which contains nerves, fibrous tissues, and muscle bundles (marshall bundle), is adjacent to the vom.2) the lom is a trigger of ectopic beats initiating paroxysmal atrial fibrillation (af)3) and is inner... |
Strong evidence shows that pilonidal disease originates in the epidermis, in a midline stretched hair follicle . Early pilonidal changes are amplified due to deep tissue disruption from moisture, anaerobic conditions, hairs, and bacteria . On the basis of these observations, a new paradigm of origin emerges that piloni... |
Several risk factors have been confirmed, such as smoking, hypertension, diabetes, high blood cholesterol, excessive alcohol drinking, depression, and lack of exercise . As for the underlying mechanism of cad, it is reported that cardiac atherosclerosis may have a significant influence on the occurrence and progression... |
Data sources were the truven health marketscan commercial claims and encounters and the marketscan medicare supplemental databases from january 1, 2009, to september 30, 2012 . Records of patients with a copd diagnosis at any diagnosis position within the intake period from july 1, 2009, through september 30, 2011, wer... |
The carious process usually progresses as a series of exacerbations and remissions that are characterized by periods of high production of acid that are responsible for the dissolution of the hard tissues of the tooth . If allowed to proceed untreated, it results in the progressive destruction of the tooth and eventual... |
Dental trauma is one of the most painful and stressful injuries in young patients and requires both expedient and expert management by a dental practitioner . Children are always keen to explore their surroundings without realizing the risks they are exposed to . The world health organization has defined exarticulation... |
Seven consecutive patients [three men and four women aged 15 - 77 (mean, 42.7) years] admitted to our hospital with hypoglycemia between april 1, 2001 and september 31, 2002 were retrospectively studied . The time from the onset of neuroglycopenic symptoms to diagnosis ranged from 4 to 42 months . The age, sex, and his... |
An effective and adequate relationship between patient and physician during medical care is necessary for the provision of good care . Although communication skills training is being developed in medical schools, little attention is paid and less than 5% of the curriculum is allocated to communication skills education ... |
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