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Its annual incidence has been rising steadily at a rate of 2.3% since 1975 for all races within the us.1 light - skinned individuals are physiologically at a higher risk for melanoma than their dark - skinned counterparts.2 thus, much of the medical literature, current research, and public health efforts have targeted ... |
Squamous cell carcinomas (scc) constitutes about more than 90% of head and neck cancers . They form the sixth most common cancer worldwide and sixth common cause of death in males and seventh common cause of death in females in india . In spite of enormous progress in detection and treatments over recent decades, the o... |
In the last years, sophisticated intraocular lens (iol) designs, such as the multifocal and accommodating iols, with the ability of restoring distance, intermediate and near vision have been introduced in clinical practice . The designs of multifocal iols are based on a number of optical concepts that are used to creat... |
Growing evidence suggests the mood disorder is associated with insulin resistance and inflammation [1, 2] some studies have demonstrated that depressed individuals had higher glucose levels and insulin resistance when they are symptomatic [36]. Epidemiologic evidences showed that obesity correlated with depression, and... |
Titer of contact hypersensitivity (tch) is a reliable method of measuring the degree of contact hypersensitivity to parthenium plantseverity of dermatitis caused by parthenium hysterophorus varies with seasoneffect of seasonal change on patch test and tch has not been studied . Titer of contact hypersensitivity (tch) i... |
Chronic periodontitis is a multifactorial infectious disease occurs as a result of challenge between the host response and specific periodontal pathogens characterized by the manifestation of a slow irreversible damage of periodontal supporting tissue loss in a period of time . It has been shown that deep periodontal p... |
Hyperbaric oxygenation is the method to assist in improving outcomes of the treatment for stroke and global brain ischemia . When patients undergo hyperbaric oxygen therapy, they breathe 100% oxygen under greater than sea level pressure . This modality is capable of providing maximized oxygen supply due to hyperbaric c... |
Pseudomonas aeruginosa is a major nosocomial pathogen, and effective therapy represents a great challenge . P. aeruginosa strains are often resistant to antibacterial agents from different classes, including -lactams, aminoglycosides, and fluoroquinolones; some strains are only susceptible to polymyxins . The mechanism... |
A 46-year - old man was admitted to the internal medicine department for evaluation of an incidental finding of leukocytosis and hypereosinophilia . He complained of a pruritic skin rash on his lower extremities for the past eight months . No changes in bowel habits, arthralgias / myalgias or any other complaint were p... |
Age estimation is one of the most important factors employed in establishing the identity of an individual . Teeth are generally preserved for a long time making them reliable entities for age estimation . During periods of tooth development, it is possible to estimate the age by comparison with stage of eruption of de... |
Septicemia is a clinical syndrome associated with considerable morbidity and mortality . In india, neonatal septicemia is responsible for one - fourth to nearly half of the neonatal deaths next to perinatal hypoxia . Infections with pseudomonas aeruginosa is usually late in onset, nosocomial in origin and epidemic in p... |
Leukemia cutis (lc) denotes the invasion of neoplastic leukocytes or their precursors into the epidermis, dermis, or subcutis, presenting with various cutaneous lesions including papules, macules, plaques, nodules, ecchymoses, palpable purpura, and ulcerative lesions [19]. Lc is more common in the monocytic subtype of ... |
Current medical management of short bowel syndrome (sbs) involves the use of lifelong parenteral nutrition (pn). Glucagon - like peptide-2 (glp-2), an important intestinotrophic growth factor has been shown to increase intestinal absorption in sbs through augmentation of post - resection intestinal adaptation . Advanci... |
Radiotherapy, alone or combined with chemotherapy remains the most commonly used modality for the treatment of locally advanced (la) nonsmall cell lung cancer (nsclc).1 in the positron emission tomography (pet) staging era, concurrent chemoradiation (ccrt) has become the standard of care in treating la nsclc with media... |
The cornea consists of three types of cells, epithelial, stromal, and endothelial . The cornea functions as an optical lens that refracts light, but it also contributes to the rigid shell of the eyeball . In order to optimally refract light and ensure clear vision, the cornea must maintain optical transparency . This i... |
Monepantel (zolvix) was registered for the control of gastrointestinal nematode (gin) parasites of small ruminants in new zealand in 2009, and in others parts of the world in 2010 . The compound is an amino - acetonitrile derivative, showing a wide spectrum of activity against gins (kaminsky et al ., 2008). However, wi... |
The prevalence of benign prostatic hyperplasia (bph) has shown a progressive increase, owing much to an increase in the elderly population, advancement in diagnostic methods, economic growth, and desire for a better quality of life . The initial treatment of bph is mostly through medications, but some patients who show... |
The study population was based on all subjects (n = 363) with type 2 diabetes who were aged <66 years and attending a tertiary referral center at hvidre hospital during 1987 as described previously (10). Type 2 diabetes was defined as either 1) diabetes treated by diet alone or by diet combined with oral hypoglycemic a... |
The role of gap junctions in seizurogenesis has been extensively investigated in the last 10 years, but remains an area of controversy . It seems intuitively reasonable that open gap junctions, acting as electrical synapses, should enhance synchrony between cortical neurons and promote seizure activity . Experimental s... |
Etiology of the genital lesions are mainly due to herpes simplex virus (hsv), human papilloma virus (hpv) and non - specific genital ulcers . We are presenting a young unmarried hiv positive patient who presented with non - healing genital ulcer lesions while on antiretroviral therapy and subsequently responded well to... |
Two pairs of images were used to test the algorithms (figure 1), a pair of orthogonal sinusoidal gratings and a face / house pair . This variable mixing in the algorithm corresponds to physiological observations that binocular neurons in striate cortex of macaque monkey occur in various ocular dominance mixtures (hubel... |
The incidence of malrotation is 1:500 births and the symptomatic incidence is 1:6000 [1, 2]. The incidence of duodenal web as a cause of intestinal obstruction is 1:10 0001:40 000 . A 1-day - old baby girl, born by normal spontaneous vaginal delivery, was evaluated for abdominal distension and history of having not pas... |
An azygos lobe (al) is the best known and most common malformation of the lungs . It is a defect which develops during the migration of the azygos vein in the embryonic period . It is possible to find reports of procedures performed in patients with an azygos lobe in the literature [1, 2]. However, the presence of the ... |
Ever since ball performed the first closed needle biopsy in 1934, percutaneous renal biopsy has remained an essential part of the diagnostic work - up of patients with renal parenchymal diseases . Tissues obtained through this procedure are not only pivotal in determining the cause of renal disease but are also very us... |
For most decision makers, the health effect is usually the single most important benefit and hence element of any assessment of value, while cost - offsets within the healthcare system are a second key benefit . Uncertainty in the measures of cost and health gain also tends to influence decision makers . Other elements... |
Rheumatoid arthritis (ra), the most common form of inflammatory arthritis, is a progressive inflammatory disease that affects the joints . A significant percentage of patients with ra have symptoms and signs of temporomandibular joint (tmj) involvement . This is a far greater proportion than that in earlier studies, as... |
Therefore, this study analyzed changes in the ecg of tc patients over time and the differences in the ecg of tc patients from those of acs patients to examine if the results can help distinguish between tc and acs . Between march 2004 and november 2012, 37 consecutive patients with tc (12 men, 25 women) were retrospect... |
Benign prostatic hyperplasia (bph) refers to stromal and glandular epithelial hyperplasia that occurs in the zone of the prostate that surrounds the urethra . Histopathologic bph is often associated with lower urinary tract symptoms (luts), characterized by urinary frequency and urgency, a sensation of incomplete bladd... |
Since its introduction in 1972, the artificial urinary sphincter (aus) has been the gold standard treatment for the surgical management of severe male stress urinary incontinence . While numerous studies demonstrate excellent long - term aus success rates, the development of a urethral cuff erosion in some patients is ... |
Ms is a highly polymorphic disease characterized by diverse neurological signs and symptoms (e.g., optical neuritis, dizziness, disturbances in bladder control, peripheral sensory neuropathies, and/or limb weakness). In most patients (80%) ms has a relapse - remitting pattern, whereas in a minority it can be primary pr... |
Wellens sign, or the lad coronary artery t - wave inversion pattern (1), is seen in a subset of patients who often present with chest pain and are found to have specific precordial t - wave changes on ekg . Its incidence is estimated to be about 1015% of acute coronary syndrome (acs). With unstable angina patients, how... |
In 2010, we described for the first time, the previously unrecognized syndrome of rapid- onset end - stage renal disease (soro - esrd) in chronic kidney disease (ckd) patients . This syndrome was described distinct from the classic ckd - esrd progression profile of a linear, predictable, smooth, and simply time - depen... |
Adipose tissue, involved in control of metabolism, is an active endocrine organ that secrets a number of hormones and cytokines termed adipocytokines [13]. These include leptin, interleukin-6, tumor necrosis factor-, adiponectin, and resistin [210]. Adipocytokines have different effects and act through autocrine, parac... |
Although the bilioenteric anastomosis has become the traditional treatment of choice for patients with benign biliary strictures, recent studies suggested that percutaneous transhepatic therapy would be an effective and less invasive therapeutic modality.1,2 both fluoroscopy and cholangioscopy can guide the percutaneou... |
The most common complaint of patients presenting for treatment of third molars is developmental, pathological, medical deformities which is characteristic of a modern civilization . By definition, impacted tooth is a tooth which is completely or partially unerupted and is positioned against another tooth, bone or soft ... |
Recent findings suggest that atherogenesis and plaque rupture, two critical elements of cardiovascular pathogenesis leading to chronic disease burden and clinical events, result from systemic and vascular inflammatory processes . In general, infections and low - grade inflammatory processes influence the development of... |
Blepharokeratoconjunctivitis is a condition that is defined clinically as the presence of eyelid involvement by lid margin scarring, blepharitis, meibomitis, and chalazion or hordeolum, accompanied by epithelial or stromal keratitis, corneal scarring, vascularization, and thinning or perforation.1 it is a common condit... |
In most western countries, absolute numbers of brain dead patients are declining [13]. Approximately 8090% of these patients suffer from aneurysmal subarachnoid haemorrhage (sah), traumatic brain injury (tbi) or intracerebral haemorrhage (ich) [2, 47]. Progress in the prevention and treatment of these three conditions ... |
The entire sequence of the human genome is not expected to be finished for some time, and gaps are expected to persist into 2003 . In the meantime, the genome exists in' draft' form: multiple segments of sequence in which we have high confidence, placed relative to one another by mapping information of lower confidence... |
Crohn and rosenberg first reported the uc case associated with colorectal cancer development in 1925, and the association between colitis and colorectal cancer is widely accepted currently . It is assumed that chronic inflammation is a direct cause of cac; however, it is not until 10 years after disease onset when a ri... |
Posterior colporrhaphy is reported to be one of the most common gynaecological procedures performed in over 40% of women undergoing surgical correction of prolapse . Restoration of the posterior compartment, which includes perineum, rectum, and the peritoneum of the cul - de - sac, knows many approaches . The transvagi... |
Orthodontic wires are the corner stones on which the science and art of orthodontics is based . It is natural to expect that these wires undergo some sort of biodegradation in the constantly changing oral environment . Stainless steel wires have for long been the main stay of clinical orthodontics due to their outstand... |
Toxocara vitulorum is an intestinal ascarid parasite of cattle and water buffaloes (bubalus bubalis). Although the parasite may occur worldwide, it is of particular economic importance in tropical and subtropical regions, mainly due to lacking or inefficient control . T. vitulorum causes morbidity and mortality in calv... |
The dopaminergic action in the kidney is impaired in essential hypertension due to an overactivity of g - protein - coupled receptor kinase type 4 (grk4), an enzyme that desensitizes dopamine d1 receptor (d1r) [1, 3]. Over - activity of grk4 is shown to be caused by three activating variants of grk4, namely, r65l, a142... |
Gestational diabetes mellitus (gdm) is the most common metabolic complications of pregnancy, and causes fetal mortality and morbidity (1, 2). Gdm is a state of glucose intolerance with the onset or first recognition occurring during pregnancy (3) and approximately occurs in 2 - 5% of all pregnancies (4). Offspring of m... |
Metastatic brain tumor is the most common malignant brain tumors . Because of their rapid progression, early detection of metastatic brain tumors is essential for the treatment . For the early detection of the metastatic brain tumors, high - field magnetic resonance (mr) images such as 7.0 t mr images may be helpful si... |
Iga nephropathy, first described by berger and hinglais in 1968, is now one of the most common forms of primary glomerulonephritis . In most cases, it presents as the primary disease, but occasionally, it develops associated with another disease . Henoch purpura is the most frequently associated disease, there are a lo... |
Quantitative measures of sway during quiet standing give important information to clinicians planning treatments for patients1 . During quiet standing, humans move the body to maintain the center of gravity (cog) over the base of support (bos) in response to perturbation2 . To quantitatively assess balance ability duri... |
Individuals after stroke often experience sleep disturbances and changes in sleep patterns . Up to 40% of individuals with chronic stroke (defined as> 6 months following stroke) and 70% of those with acute stroke have sleep - wake disorders, including excessive daytime sleepiness, insomnia, hypersomnia, and fatigue.1 s... |
Internuclear ophthalmoplegia (ino) results from a disruption of the medial longitudinal fasciculus (mlf). This leads to loss of adduction in the ipsilateral eye and dissociated nystagmus on abduction in the contralateral eye . Ino can be associated with other neurological signs like skew deviation and ocular tilt react... |
Bacteriocins are natural peptides secreted by many varieties of bacteria for the purpose of killing other bacteria . This provides them with a competitive advantage in their environment, eliminating competitors to gain resources . However, bacteriocins from gram - positive bacteria are generally classified according to... |
The incidence of hypertension, cardiac hypertrophy, and heart failure increases significantly with aging, and age - related structural adaptations may contribute to deteriorating function of the cardiovascular system . The aging heart is characterised by myocyte loss, hypertrophy of remaining cells, and exaggerated acc... |
Although isolated cases of endomyocardial fibrosis (emf) and apical hypertrophic cardiomyopathy (aphcm) have been frequently reported in the prior literature there is only one other case report of the coexistence of both entities in the same patient . A 48yearold man from west africa with no family history of cardiac d... |
Coronary artery anomalies are rare occurrences, with an incidence ranging from 0.17% in autopsy studies to 1.3% in angiographic series . These anomalies are generally asymptomatic, but more potentially serious ones may lead to myocardial ischemia, myocardial infarction (mi) and/or sudden death . In particular, st - seg... |
Progesterone is essential for endometrial receptivity and pregnancy maintenance in the human and non - human primates12345 . As shown in table i, there are a few reports on the molecular characteristics of the window of implantation in which high density cdna microarray screening was performed for global gene profiling... |
The gold standard for the treatment of displaced acetabular fractures is the surgical anatomical restoration of the articular surface and stable internal fixation . Poor outcome in the mid - term and long - term follow - up is observed in about 20% of all operated simple fractures and in 28% of all operated complex fra... |
Prostate cancer (pca) has become one of the most common types of cancer in urinary system and the increased incidence and mortality seriously affect health in the elder male population . In china, prostate - specific antigen (psa) is present in the serum of men with healthy prostates but is often elevated in the presen... |
The link between immunosuppressive therapy and increased lymphoma risk is well established in patients who have undergone solid organ transplantation and in those with rheumatoid arthritis with or without methotrexate medication [1, 2]. Of the non - hodgkin lymphomas that develop in patients who have received a solid o... |
The tomato, one of the most scientifically investigated vegetables because of its commercial importance, is highly perishable; and postharvesting losses reach 25 to 50% . In tropical countries, there is a loss of 2050%, from harvesting to consumption [25]. It is low in calories and rich in vitamins a, c, and e and mine... |
The indiana ao - oct system used in this study has been described by liu et al . Relevant to this study, the ao - oct system used a single light source, a superluminescent diode with central wavelength of 790 nm and bandwidth of 42 nm, for ao - oct imaging and wavefront sensing . Nominal axial resolution of the system ... |
Acute- and, where possible, convalescent - phase serum samples were obtained from patients admitted to the yangon children s hospital with a clinical diagnosis of dhf (1). A patient with a confirmed case of dengue fever was one who met any of the following criteria: 1) paired sera showed a fourfold or greater rise in h... |
Does evidence exist supporting the effectiveness of sms and ch in improving health outcomes? In this brief commentary, we will suggest that such evidence does exist, in particular for diabetes, obesity, asthma, and tobacco use . Diabetes a meta - analysis of 31 studies found that self - management support, which involv... |
Each specimen was radiographically screened for anatomic defects or prior surgery before initiation of the study . The specimens were maintained in a freezer at 20c until approximately 24 hours before testing . They were thawed to room temperature, and all residual musculature was removed by careful dissection ., the s... |
20m frozen sections were obtained from fresh - frozen lower limb skeletal muscle biopsies and placed on pen membrane slides (leica) for subsequent laser micro - dissection . Cox (cytochrome c oxidase) contains subunits encoded by the mitochondrial genome and stains brown (positive) in the presence of preserved respirat... |
Recent advances have expanded the scope of surgery, which can be carried out on virtually any part of the body; however, many operations need patients to be positioned prone [], for example, neurosurgery of posterior fossa tumor, posterior spinal surgery, and percutaneous nephrolithotomy surgery . [] awake nasotracheal... |
Diabetic neuropathy is the most common diabetic complication, and 1020% patients with diabetic neuropathy suffer pain1 . Duloxetine is a serotonin noradrenaline reuptake inhibitor (snri) that has often been used for painful diabetic neuropathy in many countries because of the efficacy and favorable adverse - effect pro... |
Pregnancy is characterized by dramatic and reversible changes in cardiovascular hemodynamic to meet the increased metabolic demands of the mother and the fetus . Early changes are due, in part, to the metabolic demands brought on by the fetus, placenta and, to the increasing levels of pregnancy hormones, particularly t... |
Sodium hypochlorite (naocl) is one of the most widely used endodontic irrigants for the chemomechanical preparation of root canals because of its excellent antimicrobial action and capacity of dissolving organic materials, which increase directly with the increase of the concentration . However, the optimal organic tis... |
Since the initial description of eosinophilic leukemia, there has been much controversy over the existence of such entity . Hardy and anderson proposed the term hypereosinophilic syndrome, which is a heterogeneous syndrome in its presentation . Concluded that there was a continum of hypereosinophilic diseases with eosi... |
Thus, gastric cancer prevention is one of the most important elements in all cancer control plans around the world . It has been demonstrated that high consumption of salty foods and n - nitroso compounds cause to increase gastric cancer risk . In contrary, some dietary modifications such as high intake of fruits, vege... |
Xq28 microduplications including the methyl - cpg - binding protein 2 gene (mecp2, mim * 300005) constitute a 100% penetrant x - linked syndrome (mim #300260) associated with a distinct phenotype in affected males characterized by infantile hypotonia, mild dysmorphic features, pervasive developmental / intellectual dis... |
People who lead a sedentary lifestyle throughout most of the day do so because of work, non - active recreational activities, or convenient transportation . A crucial factor for designing seats (cushions) is buttock - seat (cushion) contact, and seated pressure is one of the most frequently studied aspects of seat (cus... |
Fruit and vegetable intake is an important indicator of diet quality and protective against certain chronic diseases . Despite these benefits, adolescents consume a disproportionate amount of nutrient poor foods, such as fast food or snack foods [2, 3] and do not meet dietary guidelines for fruit and vegetables [48]. B... |
The synaptic tagging and capture (stc) hypothesis provided a strong framework to explain how to achieve synaptic specificity and persistence of electrophysiological - induced plasticity changes . It predicts that induction of long - term potentiation creates a synapse - specific tagged state that may capture diffusible... |
Symptoms were nonresponsive to medical therapy . Magnetic resonance imaging (mri) demonstrated a multicompartmental l3 vertebral hemangioma with a bony and large epidural component with compression of nerve roots (fig . The patient initially underwent a spinal angiogram and a marked vascular supply from the left l3 lum... |
Non - carious cervical lesions are characterized by a loss of hard tissue at the cemento - enamel junction.1 these lesions are generally wedge - shaped and were previously termed idiopathic cervical erosion lesions, now referred to by grippo2 as abfractions . Grippo suggests that if the lesion were left unrestored, the... |
Oroantral communications (oac) are rare complications in oral surgery, which recognize upper molars extraction as the most common etiologic factor (frequencies between 0.31% and 4.7% after the extraction of upper teeth1), followed by maxillary cysts, tumors, trauma, osteoradionecrosis, flap necrosis and dehiscence foll... |
Current understanding on the pharmacokinetics of drugs in neonates with hypoxic ischemic encephalopathy (hie) is limited . In addition to brain injury, global hypoxic insult often results in acute liver and kidney injury that can impact drug clearance. (15) in addition, therapeutic hypothermia is recommended for modera... |
Cytoskeletal assembly of actin filaments (f - actin) plays an essential role in determining the morphology and self - propelling movement of living cells . To gain insight into the dynamic behavior of living cells, an artificial cell model (cell - sized giant liposomes with cytoskeletal proteins) has been developed usi... |
A retrospective search was conducted in the archives of department of oral pathology and microbiology, college of dental sciences, davangere between 2001 and 2013 . The cases diagnosed as okc, inclusive of both the variants were selected for the study, based on final histopathological reports . Data regarding age, gend... |
The predesigned and pretested data collection tool adopted during data collection was a questionnaire that was developed at the institute with the assistance from the faculty members and other experts . This semi - structured self - administered anonymous questionnaire contained questions relating to the sociodemograph... |
Noninvasive management through inotropic support allows frequent clinical improvement, yet one is repeatedly confronted with refractory cases necessitating more invasive support . The idea of a mechanical assistance first appeared in the 1950s, yet the first device which is the intra - aortic balloon pump (iabp) only a... |
Atresia refers to a congenital obstruction with complete occlusion of the intestinal lumen and accounts for 95% of obstructions in neonates . It is detected by prenatal ultrasonography in second or third trimester and confirmed at birth by features of intestinal obstruction . Although, new operative techniques and peri... |
It is not a totally scientific or objective discipline, nor is it totally an art form . Esthetics in complete denture prosthesis covers a spectrum of restoration of facial contours to an understanding of tooth size and shape, gingival margin contour and color.1 with respect to esthetic appearance of the face, maxillary... |
To meet the healthy people 2010 goal that 30 percent of pregnant women who smoke will quit (this rate was 14 percent in 1998), public and private insurers need to implement evidence - based, cost - effective cessation programs (u.s . Department of health and human services, 2000). Maternal smoking exerts immediate harm... |
Glucose - regulated protein 78 (grp78) is an endoplasmic reticulum (er) chaperone protein belonging to the heat shock protein 70 family . It consists of two functional domains, a 44 kda n - terminal atpase and a 20 kda c - terminal polypeptide - binding domain, and a variable 10 kda c - terminal tail of unknown functio... |
Minimally invasive surgery is nowadays a consolidated alternative to the traditional open surgery for a number of operations . Minimally invasive surgical techniques include laparoscopy, single site surgery, and natural orifice transluminal endoscopic surgery . Laparoscopy has proved to be less traumatic for the patien... |
Melanoma causes about 80% of all skin cancer deaths, and is notoriously resistant to current treatments . Less than 25% of metastatic melanomas respond to existing therapies.1, 2 in addition, melanoma often reoccurs after initial response, and these cases can be extremely aggressive . Patients with advanced melanoma ha... |
A little over a decade ago, it was generally accepted that the human heart is a terminally differentiated organ lacking any intrinsic regenerative capacity . After birth, the cardiomyocytes undergo a final round of cell division with a portion of the cardiomyocytes becoming binuclear and/or polypoid [14, 82, 83]. The o... |
A 79-year - old chinese female has been on follow - up at a specialist dermatological center in singapore for psoriasis vulgaris . Following a pustular flare in october 2004, a year later after having consumed a cumulative mtx dose of 390 mg, she noted the appearance of a new rash on the right antecubital fossa . She d... |
Tinea imbricata or tokelau is fungal infection of the skin, which manifest with multiple concentric rings of erythematous papules, pustules, scaling and crusting, caused by trichophyton concentricum, an anthrophphillic dermatophyte . Tinea pseudoimbricata or tinea indecisiva are the terms given for similar clinical pre... |
Store dicom images correctly in a very easy set - up in a fast, secure and stable environmentallows adaptation of the software to perform a certain task based on specific needsallows easy integration into an existing environmentreduce the possibility of inappropriate anonymisation store dicom images correctly in a very... |
A 42-year - old female patient presented with complaints of severe pain in her left leg, muscle weakness, difficulty in climbing, and descending stairs, weight loss, loss of appetite, and sleep disorders with an onset dated back 3 months ago . Within the previous 3 months she had lost 15 kg (from 65 kg down to 50 kg). ... |
As the most frequently diagnosed cancer and second leading cause of death in women worldwide, breast cancer is considered the most troublesome cancer among women today . Currently, the development risk of breast cancer in american women is one in eight, and the metastatic form of breast cancer has a 5-year survival rat... |
Physical activity is one of the most important elements of a healthy lifestyle of people of different ages1 . Deficiency of physical activity increases the risks of obesity, type 2 diabetes, osteoporosis, myocardial ischemia, degenerative changes on joints and certain cancers2, 3 . The results of empirical studies indi... |
Matrix metalloproteinases (mmps) are essential to the remodeling of the extracellular matrix . While their up - regulation facilitates aging and cancer, they are essential to epidermal differentiation and the prevention of wound scars . The pharmaceutical industry is active in identifying products that inhibit mmps to ... |
Traumatic spondylolisthesis of the axis, the so - called hangman fracture, was first discovered by haughton in 1866 in dead criminals from judicial hanging, and schneider et al in 1965 officially named this kind of fracture . It is characterized by bilateral c2 pars interarticularis fracture with a variable degree of t... |
A 56-year - old man presented with a newly - developed large mass in his left posterior thigh . He had been treated 6 months earlier with palliative chemoradiation for unclassified sarcomas of the cervical spine, the right femoral head, and both lungs . Magnetic resonance imaging revealed a poorly marginated, 8.5-cm, h... |
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