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Papaver somniferum l. is known as opium poppy, which has been used as a medicinal remedy for its sedative, anesthetic, analgesic, and antidierrheal effects for thousands of years . There are ancient documents mentioning about the medicinal properties of opium poppy such as the de materia medica written in a.c . 65 by p... |
Rheumatoid arthritis (ra) is a chronic inflammatory disease characterized by the progressive destruction of cartilage and bone in the synovial joints, which is associated with proliferation of synovial cells and infiltration of activated memory t cells, antigen - presenting cells (apcs) and plasma cells.1 proposed etio... |
Graft - versus - host disease (gvhd) is an important complication of bone marrow transplantation and is known to induce sweat gland abnormalities . In acute gvhd, about 80% of the cases contain two patterns of sweat gland abnormalities: a cytopathic pattern consisting of a combination of basal vacuolopathy with lymphoc... |
Beta - blockers such as esmolol have been used in anaesthesia practice to blunt the adrenergic response to various stimuli during perioperative periods such as in laryngoscopy, intubation, surgical stimulation and tracheal extubation . The optimal approach to achieve the dual aims of obtunding the transient autonomic c... |
A 54-year - old man was admitted to our department by ambulance, with an iron fork being penetrated into his upper neck, through the skull base and into brain (fig . On physical examination, the man had a glasgow coma scale (gcs) score of 9, with hemiparesis on his right limbs, and right lower extremity babinski sign p... |
In august 2004, a previously healthy 31-year - old male was referred to the emergency department due to a 5-day history of progressing abdominal pain . Physical examination revealed diffuse tenderness of the abdomen, without significant rebound or guarding . An emergency non - enhanced computed tomography (ct) of the l... |
Given the current worldwide obesity crisis, waist - to - hip ratio (whr) and body mass index (bmi) are recommended anthropometric measures to physicians to serve as proxies of metabolic and cardiovascular risk in women and men, with whr being a better predictor of cardiovascular disease and diabetes than bmi ([13], but... |
Angiosarcoma is a rare malignant tumor, accounting for only 1%5% of all soft tissue sarcomas . Cutaneous angiosarcoma is the most common presentation of this neoplasm, which affects the facial skin and scalp regions . Head and neck angiosarcoma is usually seen in patients older than 60 years of age, and slightly more o... |
The choroid is the vascular structure between the retinal pigment epithelium (rpe) and lamina fusca layers of the sclera . It is one of the regions with the highest blood circulation ratio in the human body, and structurally and functionally normal choroidal vessels are essential for retinal physiology . Detailed exami... |
Prescription is the written order of the physician which is directly conveyed to the patient . It contains information pertaining to dose of the drug, route of administration, frequency of administration . Prescribing appropriate drugs in right doses is an integral part by which a physician can influence the patient's ... |
Twenty - two volunteers were included, comprising patients with long - standing c - peptide negative t1d and t1d poor (t1dp) or t1d improved (t1di) glycemic control and nondiabetic humans without family history of diabetes (control subjects [con]) (table 1). All participants underwent clinical examination including med... |
A distinctive feature of cancer cells is their ability to dissociate from the primary tumor and establish metastases at various sites . The common routes by which cancer cells spread include local invasion, and lymphatic, hematogenous, and peritoneal dissemination . The hematogenous and lymphatic pathways are well - es... |
Normal abdominal cavity fluid of adults is less than 50 ml, mainly playing the role of lubrication in the cavities and is generally not easily collected . A large amount of abdominal cavity fluid is accumulated after surgery for gastrointestinal or retroperitoneal tumors, and it is standard practice to place a drainage... |
A characteristic feature of many solid tumors and hypoxia - treated cancer cells in culture is the expression of carbonic anhydrase ix (ca ix), an extracellular facing enzyme that catalyzes the interconversion of co2 and h2o to hco3 and a h. ca ix works in concert with cell membrane transporters to regulate the ph of t... |
Double - balloon enteroscopy (dbe) is the promising tool for the diagnosis and treatment of small bowel diseases, and dbe has provided the definite diagnosis for most small bowel diseases which previously could be treated by only surgical resection . However, generally, it takes a longer time to perform dbe than the ot... |
Yttrium oxide partially stabilized tetragonal zirconia polycrystal (y - tzp), introduced to the prosthodontic field in the early 1990s as an all ceramic core material,1 has favorable esthetic characteristics, superior mechanical properties and biocompatibility.2 - 6 due to its mechanical properties such as high strengt... |
A 75-year - old right - handed woman was admitted because of the abrupt development of mental confusion, left hemiparesis, and dysarthria . One day before admission, she developed weakness in her left arm and disorientation, followed 20 hours later by inappropriate speech, agitation, and dysarthria . She had a history ... |
Robotic surgery (rs) was adopted by urologists for radical prostatectomies in the treatment of prostate cancer during the late 1990s despite the lack of strong scientific data to support its advantages over the laparoscopic technique . As economic pressures continued to drive the use of rs, more data became available a... |
Owing to its protected retroperitoneal location, pancreatic injury following blunt trauma is rare, with an incidence rate of <2% . Early and accurate identification of such injuries are imperative to avoid high morbidity and mortality associated with ductal injuries . However, proponents of early surgical intervention ... |
Teaching students about phenomena which enable anti - oppressive practice (aop) presents both a challenge and an opportunity to help students see beyond everyday events and consider how their own practice and the environments in which they work may disable patients and even discriminate against them . The concept of ao... |
Stroke is the major cause of adult disability worldwide . Up to 80% of the stroke patients endure motor deficits that severely lowers the quality of their daily lives [1, 2]. Most of the stroke survivors could obtain a certain degree of motor improvement after various therapies, including medication, acupuncture, movem... |
These are presented in the systemic review by jacob and colleagues in this issue of critical care . Based on the principles described by starling in 1896, intravenous administration of hyperoncotic fluids under physiological conditions produces transient hypervolemia that may be augmented by intravasation of interstiti... |
A consecutive series of 222 diabetic patients with foot osteomyelitis were treated surgically in the diabetic foot unit at la paloma hospital (las palmas de gran canaria, canary islands, spain) between 1 october 2002 and 31 october 2008 . From the entire series, including 213 bone cultures with 241 isolated organisms, ... |
Erythrocyte sedimentation rate (esr) is one of the most commonly requested laboratory tests prescribed by physicians (1). Its rate is dependent on various physiologic and pathologic factors including hemoglobin concentration, ratio of plasma proteins, serum lipid concentration, and plasma ph (2). This limitation has no... |
Episodic ataxia (ea) syndromes are heritable diseases characterized by dramatic episodes of imbalance and incoordination (jen et al ., 2007). Ea is clinically and genetically heterogeneous, with at least seven subtypes described to date . Ea type 2 (ea2), the most common and the best characterized subtype, is defined b... |
The desire to measure progress in reducing the burden of excess morbidity and mortality as well as the need to establish reasons for existing health gaps between the rich and the poor continues to persist within and across societies . This desire also continues to propel efforts aimed at examining vertical and horizont... |
Living cells constantly monitor their own state and their surroundings in order to respond effectively to changes in them . Photoactive signaling pathways rely on proteins with bound organic cofactors providing the possibility to sense light stimuli through cis trans isomerization such as in the vision process or via e... |
In the eukaryotic cell, sphingolipids make up an imperative set of regulatory molecules and they are involved in a broad array of cellular activities such as cell growth, inflammation, checkpoint, angiogenesis, and stress stimuli [13]. Baker's yeast saccharomyces cerevisiae has been used by various researchers as a mod... |
The ability of transition metal polypyridyl complexes (e.g., scheme 1, 1 and 2) to efficiently convert visible light energy to electrochemical potential has long been appreciated in applications ranging from solar energy conversion to the study of biological electron transport phenomena . The design of synthetically us... |
Synchrotrons are magnificent x - ray sources that use an extensive arsenal of x - ray optics to tailor the x - ray beam for a wide sampling of experiments . X - ray transmission mirrors (tms) are one type of x - ray optic which has been used in the past, but they have not been used in 15 to 20 years because of mechanic... |
Necrobiosis lipoidica (nl) is a rare idiopathic cutaneous condition strongly, but not exclusively, associated with diabetes mellitus (dm). Nl lesions appear as yellowish - brown telangiectatic plaques usually localized on the pretibial skin of young adults or middle - aged subjects, with a female - to - male ratio of 3... |
Primary pigmented nodular adrenocortical disease (ppnad) is rare and manifests as acth - independent cushing's syndrome (cs). It can be associated with carney's complex and has a characteristic gross and microscopic appearance . A 15-year - old boy presented with puffiness of face, progressive weight gain, increased pi... |
The development of superacids as non - nucleophilic solvents allowed detailed studies of highly reactive acidic and electrophilic organic dications and polycations . For example, the teams of olah and hogeveen studied the remarkable properties of such superelectrophilic dicationic species as 13 (scheme 1). The reactivi... |
Alzheimer s disease (ad) is one of the most common forms of dementia . The clinical manifestations of ad include loss of memory, and behavioral and cognitive disorders . The survival time for patients with ad is generally 4 to 6 years after diagnosis ., accumulating evidence shows that genetic factors might be involved... |
Data have been deposited in repository https://www.ncbi.nlm.nih.gov/bioproject/269542 and raw sequence files (s_cgatgt_1.fastq.gz and s_cgatgt_2.fastq.gz) are also available under the accession number srp105770 (https://www.ncbi.nlm.nih.gov/sra/?term=srp105770). In this 21st century, bacterial resistance towards antibi... |
As one of the largest populated countries in the world, the people s republic of china is facing serious problems associated with aging . According to the chinese national bureau of statistics, the number of people aged 65 years and older increased to 127 million in 2012, representing approximately 9.4% of the total po... |
Note: all animal procedures must be approved by iacuc or equivalent . All surgical equipment must be sterilized prior to surgery . Sterile gloves, drapes and gauze must be used . Obtain 6 week old mus musculus cbysmn.cb17-prkdc scid / j male mice or other immunocompromised strain of mouse . Sterilize all surgical instr... |
Orthotopic liver transplantation (olt) has had a great impact on patients with end - stage liver disease since the national institutes of health consensus development conference in june 1983 and it has also been the most effective treatment for patients with acute liver failure related to virus infection or other etiol... |
The frequency of dysphagia is reported to range from 29% to 81% after stroke (1, 2), and over 17% after traumatic brain injury (tbi) (3). Dysphagia after stroke or other brain injuries is known to be a risk factor for complications such as aspiration pneumonia, dehydration, and malnutrition . These complications influe... |
Recently, newer techniques for esophageal functional testing such as wireless ph capsule monitoring, duodenogastroesophageal reflux detection and esophageal impedance testing have been introduced and are currently available in clinical practice . However, ambulatory 24 hr esophageal ph monitoring is still widely used a... |
The online version of this article (doi:10.1007/s00248 - 008 - 9481 - 9) contains supplementary material, which is available to authorized users . Salt marshes are among the most productive ecosystems known and vital components of the coastal marine landscape . They sequester enormous amounts of carbon and act as a sig... |
It is well known that percutaneous coronary intervention (pci) is superior to fibrinolysis for st elevation myocardial infarction (stemi), but fibrinolysis remains a good option for centers without pci facility or geographical inaccessibility . Several trials have consistently shown no differences in mortality between ... |
Oral cancer is a global health problem with increasing incidence and mortality rates . Around 300,000 patients are annually estimated to have oral cancer worldwide . Although representing 2 to 4% of the malignancies in the west, oral cancer accounts for almost 40% of all cancers in the indian subcontinent . The followi... |
Congenitally bicuspid aortic valve (cbav) is the most common inborn cardiovascular anomaly [1, 2] with a prevalence of 0.9% to 2% in the general population . Besides the potential for the early degeneration of the valve itself, cbav may also lead to ascending aortic dilatation (aad), dissection and/or rupture [4, 5]. T... |
The directional change of nystagmus, which is definitely identified by a positional nystagmus test, can be related to central vertigo . In 1920, barany defined positional nystagmus as a nystagmus that occurs with keeping the head in a specific position, which is a major sign of lesion in the central vestibular system .... |
Magnesium (mg) is the fourth most common cation and the second most common intracellular cation1,2). Mg is necessary for muscle contraction and neuronal transmission, and also acts as a cofactor for carbohydrate, protein and energy metabolism1,3,4). Newborn infants with hypermagnesemia might present with respiratory de... |
To describe a case in which descemet's membrane interfered with aqueous humor drainage through an express mini shunt . A 70-year - old male, diagnosed with corticosteroid - induced glaucoma in his right eye, presented to our hospital . Topical betamethasone treatment was discontinued, and the patient was treated with i... |
Hospital ceos worldwide are grappling with similar challenges, including issues related to patient safety, quality, best practices, and how to best minimize costs [14]. Ceos in the united states have the opportunity to meet and seek solutions regularly, for example, at seminars conducted by the american college of heal... |
Cerebral venous thrombosis (cvt) is an uncommon cause of stroke, representing 0.51% of all strokes . Cvt is reported in 28% of patients with pnh . Approximately, one - third of cvt patients develops intracerebral hemorrhage (ich). Identification of these patients is critical given that the pathophysiology underlying he... |
Leukemia is the most common childhood cancer worldwide . Among the major types of leukemia, acute lymphoblastic leukemia (all) contributes to 76% of all leukemia cases and 43% of all deaths of pediatric leukemia patients in the us . All is a malignant blood disorder that originates either from the t- or b - cell lineag... |
Conjunctivitis is a very common cause of bilateral as well as the unilateral red eye . Most of the infections are of viral and bacterial etiologies . However, parasitic infestations may also manifest as unilateral red eye . Although rare, the occurrence of exoparasitic maggot infestations of nose and eye in human being... |
Pituitary adenomas reported an overall prevalence of 16.7%8) comprise a diverse group of tumors . However, they may grow large and extend into surrounding structures resulting in neurological complications including visual impairment6). If pituitary adenomas are not treated, vision will continue to deteriorate and blin... |
Several labs have made key contributions to our understanding of how surfaces are sensed by bacteria (highlighted in figure 1). These reports relate the signal transduction events involved in linking adherence to a specific physiological response . Scientists are very interested in discerning the molecular mechanisms i... |
The online version of this article (doi:10.1007/s13555 - 015 - 0086 - 1) contains supplementary material, which is available to authorized users . Verruca vulgaris, also known as common warts, are benign skin growths caused by a viral infection of the skin . The cause of the condition is the human papilloma virus (hpv)... |
Ectodermal dysplasias (ed) are a group of inherited disorders characterized by dysplasia of tissues of ectodermal origin primarily hair, teeth, nail, and sweat glands . Clinically, ed may be broadly classified into hypohidrotic and hidrotic form . It is characterized by abnormalities comprising sparse hair (hypotrichos... |
A consecutive of 16 patients who presented to sgnhc with acute st elevation mi complicated by cardiogenic shock were studied . Among them, 3 patients presented with concomitant rv infarction . Those patients who presented with st elevation mi with cardiogenic shock with mechanical complications such as papillary muscle... |
Neonates represent an ideal population for the investigation of the biological dispositions that guide humans to acquire their native language . Neonate studies reveal how we begin processing speech, and inform us about the cognitive faculties that we possess before the accumulation of significant linguistic experience... |
Birth weight has classically been considered as the most significant predictor of neonatal mortality . In developed countries, improvement of neonatal care, advances in neonatal ventilation, and in particular the use of pulmonary surfactant have not only reduced preterm neonatal mortality, but also increased survival f... |
Glioblastoma is the most common primary brain tumor and among the deadliest human cancers . Because of its location, aggressiveness, and diffuse growth pattern, therapy for glioblastoma is tremendously challenging and only a small improvement in survival has been achieved over the past 30 years . This is thought to be ... |
Non - contact detection of basic human functions such as respiration using doppler radar is particularly useful in comparison to respiration belts which are simply inconvenient or even impractical; for instance, in long term sleep monitoring and respiration monitoring of burn patients or patients with dermatological co... |
Ischemia and reperfusion injury takes place during major hepatectomies due to the need for the use of vascular control techniques, as well as in liver transplantation and liver trauma . Although such maneuvers are invaluable in preventing excessive blood loss, they result in the production of cytokines and reactive oxy... |
These are supra - major oncosurgeries because they involve extensive radical resection over a prolonged period and pose a challenge to the anaesthesiologists due to many factors . The tumours being vascular cause massive blood loss and need massive transfusion which can cause complications . Patients are operated in un... |
Age - related macular degeneration (amd) is the leading cause of legal blindness in the us.13 neovascular amd may cause vision loss secondary to subretinal fluid, hemorrhage, intraretinal edema, or scarring.3 it is well established that vision loss from neovascular amd is dramatically reduced in eyes treated with intra... |
Trichomonas vaginalis, an anaerobic flagellated protozoan, is the causative agent of human urogenital trichomoniasis with worldwide distribution . This infection is associated with the increased risk of adverse pregnancy outcomes, incidence of cervical neoplasia, infertility and a number of infections, significantly hu... |
Supplementary material is available for this article at 10.1007/s13659 - 012 - 0023 - 2 and is accessible for authorized users. |
We report here 2 patients with a common history of abdominal pain that was associated with acute onset of intestinal obstruction . In both patients, histopathology reports were consistent with pancreatic tissue in the submucosal part of the small bowels . A 72 year - old man presented to the er, because of acute onset ... |
Antipsychotic drugs are generally categorized as typical antipsychotics (sometimes referred to as first - generation or conventional antipsychotics, or neuroleptics) and atypical antipsychotics; both are approved for the treatment of acute and chronic psychoses (ie, schizophrenia), mania, agitation, and other psychiatr... |
Stiff - person syndrome (sps) is an autoantibody - mediated disease against the gabaergic (gamma - amino butyric acid) neurons . Due to decreased gaba neuron function, which normally is inhibitory, autoantibody against glutamic acid decarboxylase (gad) in serum or cerebrospinal fluid (csf) is supportive for the diagnos... |
Although clathrin - mediated internalization has been investigated for many years, new technologies keep providing us with novel insights into its underlying mechanisms, with an unprecedented scale down to molecular details regarding the structure and dynamics of the proteins involved . The plasticity of clathrin - med... |
Breast cancer is the most frequently diagnosed cancer in women and is the leading cause of cancer death in females worldwide, accounting for 23% of all cancer cases and 14% of cancer deaths . Many risk factors related to breast cancer tumorigenesis have been identified, such as female sex, increasing patient age, famil... |
Silver nanoparticles have been known for the variety of applications in various fields such as catalysis, electronics, optics, medicine, and environment . Particularly, ag nanoparticles find applications in diagnostic biomedical optical imaging, molecular labeling, spectrally selective coating for the solar energy abso... |
Electrical impedance tomography (eit) is an imaging technique that produces an image of the spatial distribution of the electrical impedance of an object from electrical measurements made with an electrode array on its periphery [13]. Image reconstruction in eit is an inverse problem in which the electrical impedance o... |
Rib osteomyelitis is rare and usually occurs in patients with predisposing factors such as pneumonia and/or lung empyema, chest trauma, chronic granulomatous disease and neutropenia, sickle cell disease, thalassemia or disseminated fungal infections,,, . We report here the first case of early sternum and rib osteomyeli... |
In red algal ecological, physiological and aquaculture studies, there is a need for a quick, easy and reliable method for determining phycoerythrin (pe) and phycocyanin (pc) content . One of the most frequently cited phycobilin quantification techniques (beer and eshel 1985) utilizes the spectral properties of crude aq... |
Nearly two million people die every year from tuberculosis and despite national tuberculosis control programmes operating in many countries; eight and a half million new cases appear each year to challenge public health . The south - east asia region bears the major brunt of the global tb burden harboring 38% of the wo... |
The activities of firefighters mainly include the use of firehoses, manual lifting, or tools for fire rescues . Factors that cause low back pain may include, ascending a ladder, lifting weights, moving the body, stretching the body, or excessive firefighting work . Musculoskeletal disorders of firefighter, in particula... |
Perioperative transfusion of red blood cells (rbcs) has been associated with increased mortality, morbidity, costs and decreased long - term survival after cardiac surgery [1, 2]. Unnecessary transfusion might cause postoperative complications and subsequent hospitalisation costs [1, 3]. In an earlier report, we identi... |
External ventricular device (evd) is useful in monitoring intracranial pressure (icp) in patients with severe traumatic brain injury and abnormal computed tomography (ct) scan of the head . However, the presence of evd is a well - known risk factor for infection of central nervous system (cns) with the incidence of 118... |
The percentage of mothers over 40 years old has been increasing rapidly, peaking in 2011 at 3.6% . The recent tendency in japan to marry later is a likely factor in this increase, but so is the widespread use of fertility treatment, including assisted reproductive technology (art). According to the japanese art statist... |
Papers by the two physicians e. timoni and g. pilarini, published in philosophical transactions in 1714, made the technology known to savants . The wife of the english ambassador in constantinople, she had her young son treated in 1718 . When the family returned to england, his sister was inoculated by the surgeon mait... |
First parity sows were submitted to an ovulation - induction protocol, intermittent suckling (is), during lactation . Sows were humanely euthanized at day 9 (d9e) and day 30 (d30e) of gestation for embryo collection . An additional control group of day 30 embryos (c28) was also collected from control sows bred after we... |
Recent improvements in syphilis screening have been made possible by the introduction of rapid syphilis tests (rsts), which hold several advantages over the traditional rpr, including not requiring laboratory infrastructure (e.g. Electricity and equipment) and their ability to be used correctly by different health prof... |
The novel influenza a (h1n1) outbreak was declared a pandemic by the world health organisation (who) on 11th june 2009 . In the united kingdom (uk), 474 deaths had occurred by the end of the 2009/10 influenza season with the highest case - fatality rate among the over 65-year age group [1, 2]. Vaccination is one of the... |
Direct testing for the syphilis agent in clinical specimens can be defined as the detection of t. pallidum subspecies pallidum (subsequently simply refer to as t. pallidum) whole bacteria or components in human tissues or fluids . While the diagnosis of syphilis relies primarily on clinical and serological findings, di... |
However, diagnosis and treatment have not always been so clear . In fact, the categorization and the research on autoimmune - mediated neurologic symptoms, often in combination with a primary cancerous disease, did not start until the 1950s, since it required certain equipment and knowledge to collect evidence . Three ... |
Blood pressure (bp) measured in the clinic does not provide comprehensive information about an individual s bp profile and may be of limited prognostic value, thus requiring out - of - office bp monitoring.1,2 home bp can be measured repeatedly in the comfort of the patient s own home in a relaxing environment, which p... |
Anterior crossbite is the term used to define an occlusal problem involving palatal positioning of the maxillary anterior teeth relative to the mandibular anterior teeth . Anterior crossbites can be either dental or skeletal in origin, whereas, anterior dental crossbites originate from the abnormal axial inclination of... |
Cutaneous metastases occur in 0.7~0.9% of all patients with cancer, and the most frequent origins of cutaneous metastases are the breast, lung and colon cancer1). There are scant reports in the literature on the frequency of skin metastasis as the initial manifestation of a malignancy2 - 6). The most frequent sites of ... |
An internal hernia (ih) is an infrequent cause of small bowel obstruction (sbo), with a reported autopsy incidence of 0.2 to 0.9%, and is the cause of small - bowel obstruction in 0.6 to 5.8% of the cases [1, 2]. Abdominal computed tomography (ct) plays an important role in the evaluation and management of patients wit... |
Lupus membranous nephritis (mn) is relatively rare in children [2, 3]. Histologically, it is characterized by subepithelial immune deposits along the peripheral capillary loops leading to uniform thickening of the glomerular capillary wall . Mn presents with various clinical signs ranging from nephrotic syndrome (ns) t... |
In recent years, the number of people ascending to high altitudes worldwide has clearly increased . However, acute mountain sickness (ams) is a major obstacle faced by many people after arrival at high altitudes . Ams is a common syndrome encountered particularly by lowlanders after rapidly ascending to altitudes above... |
It is generally assumed that the efficacy of anticancer immunotherapy is hampered by immune suppressive and tolerogenic mechanisms, including soluble factors, produced by both neoplastic and other tumor - instructed immune suppressive cells . Neuroblastoma (nb) is a pediatric neuroectodermal solid tumor with a heteroge... |
Th17 cells are known as a distinct lineage of cd4 t cells, which are promoted by antigen - presenting cells (apcs) through il-1 (in humans)/tgf-1 (in mice), il-6, and il-23 [14]. Th17 cells are one of the main sources of il-17 (all referring to il-17a in this review), which functions by recruiting neutrophils . Neutrop... |
It also depicts summary of the pattern of milk yield determined by the biological efficiency of the cow . The cost of milk production depends to a large extent on the persistency of lactation, that is, the rate of decline in production after peak milk yield . High persistency is associated with a slow rate of decline i... |
Multiple sclerosis (ms) is a chronic inflammatory demyelinating disease of the central nervous system (cns). Though the exact cause of ms has not been discovered, it is believed that in a genetically predisposed individual, some environmental trigger leads to the onset of the disease.1 ms can present in several forms, ... |
Since the success of rituximab and trastuzumab for treatment of nonhodgkin s lymphoma and breast cancer, respectively, people realized a huge therapeutic potential of monoclonal antibodies (mabs) and rushed into development of therapeutic abs against cancers . In the commentary magic bullets hit the target published in... |
Exposure to direct ionizing radiation can result in programmed cell death due to the accompanying dna damage . Lysophosphatidic acid (lpa, 1-acyl-2-hydroxy - sn-3-glycerophosphate) (1, figure 1) is a growth factor - like lipid mediator with antiapoptotic actions elicited via a set of g protein coupled receptors . Lpa g... |
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