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The most frequent statistical tool to address the relationship among a dichotomous response and other covariates is logistic regression . In statistics, logistic regression is modeled with a logit link that is used for prediction of the probability of the occurrence of an event by fitting data to the logistic curve . I...
Ceramic brackets were introduced in orthodontics to meet increasing esthetic demand among orthodontic patients nowadays; however, many factors should be taken into consideration to avoid the high frictional forces generated between the ceramic bracket and the orthodontic archwire, which may interfere with orthodontic t...
The current study is based on prospective data from the german and austrian dpv documentation system (diabetessoftware fr prospektive verlaufsbeobachtung) (12,13). Within the framework of the quality assurance and scientific research project dpv, german and austrian diabetes centers (hospitals and practices) document t...
Acute bilateral isolated internal ophthalmoplegia, i.e., mydriasis without external ophthalmoplegia, is a rare manifestation . Postinfectious internal ophthalmoplegia can be associated with botulism, syphilis, fisher syndrome (fs), bickerstaff brainstem encephalitis (bbe), and guillain - barr syndrome (gbs); it is usua...
Motor fluctuations eventually emerge in most parkinsonian patients, and disease progression as well as early initiation and longer duration of levodopa therapy have been identified as risk factors . The incidence of motor fluctuation in patients with striatonigral degeneration (snd) is unknown . We report a snd patient...
Breast cancer is the most common type of cancer among females, as well as the second leading cause of cancer mortality among women . In 2017, an estimated 255,180 new cases of invasive breast cancer are expected to be diagnosed in women in the u.s ., along with 63,410 new cases of noninvasive (in situ) breast cancer . ...
Mycotoxins are secondary metabolites of molds which are associated with certain disorders in animals and humans . In addition to being acutely toxic, some mycotoxins are now linked with the incidence of certain types of cancer, and it is this aspect which has evoked global concern over feed and food safety, especially ...
Effective oral drug administration is desirable but challenging owing to the nature of the gastrointestinal tract . The highly acidic ph in the stomach and the presence of enzymes such as pepsin can cause protein degradation (allemann et al 1998). Secreted pancreatic enzymes in the lumen of the intestine and membrane -...
Self - assembly techniques have become increasingly popular as a tool to create controlled release systems for drug delivery . One such technique is layer - by - layer (lbl) self - assembly, which was pioneered by decher [1, 2]. Based on this method targeted release of bactericides into an infected chronic wound can be...
Although the etiology of preeclampsia remains unknown, it is suggested that preeclampsia is associated with intervillous and spiral artery thrombosis, vascular endothelium damage and abnormalities of coagulation, leading to inadequate maternal, fetal and placental circulation.1 immunologic adaptation disorders, abnorma...
Urinary bladder cancer (ubc) is the 4th and 9th most frequent cancer diagnosed in men and women, respectively, in the united states . It was estimated that 70,980 new cases of ubc and 14,330 related deaths would occur in the united states in 2009 . The presence of microscopic or macroscopic metastases at diagnosis is r...
Alzheimer s disease (ad) is the most common neurodegenerative disease especially among elderly people . Aging is the most important etiological factor in ad which is rapidly becoming very common all around the world especially in industrialized countries . Two major hallmarks of ad are -amyloid plaques deposition and c...
Glomerular abnormalities in immunofluorescence and electron microscopic analysis have been noted in more than 50% of patients with cirrhosis while performing an autopsy and renal biopsy . Although cirrhosis has been associated with a variety of glomerular lesions, mesangial proliferation with immunoglobulin a (iga) dep...
Os is a primary malignant bone tumor characterized by the direct formation of immature bone or osteoid tissue by the tumor cells . The classic os is a rare (45% of all malignant bone tumors) highly malignant tumor [1, 2], with an estimated incidence of 3 cases / million population / year . Os arises predominantly in th...
While driving, people with hemiplegia have difficulties not only in keeping a safe distance from the car ahead, maintaining a proper speed, and responding quickly1, but also with car ingress and egress2 . Car ingress and egress are challenging tasks for people with hemiplegia, especially when they cannot open the door ...
Sleep disordered breathing (sdb) surgery has taken its initial steps from the first tracheotomy up to the pioneering applications of robotics in the new millennium . When sher and colleagues published the unsatisfying results of surgery in patients with hypopharyngeal obstruction, they were probably still not aware tha...
Genome - wide association (gwa) studies using arrays are now widely used to map loci contributing to complex disease in human populations [13]. However, high cost limits widespread use of gwa . One approach which substantially reduces the cost is dna pooling . In pooling, instead of individually genotyping every person...
In the last decades the results of the treatment of hodgkin lymphoma (hl) patients have improved, they are cured, and now we have to be faced with the late complications of the lymphoma and/or the treatment of these, which can both influence the long - term survival and the quality of life of the patients . The radioth...
Hepatocellular carcinoma (hcc) is one of the most common cancers in the world, being the fifth in terms of incidence and third in the total number of deaths . In japan, the death number from hcc exceeds 30,000 per year [2, 3], which has been caused predominantly by chronic liver inflammation induced by hepatitis viruse...
The frequency of gastric polyps is 710% and they are usually present in two types as foveolar and pyloric gland [1, 2]. This neoplasm was defined for the first time by elster in 1976 . In 1990, watanabe et al . Pyloric gland adenoma has been reported to originate from the duodenum, gallbladder, pancreas, rectum and het...
Schizophrenia, sz (mim 181500) is a severe psychiatric disorder which affects ~1% of the general population and has a strong genetic component . However, the model of transmission is complex and is most likely polygenic . Over the last two decades, linkage and association studies have identified a number of chromosomal...
The american board of cosmetic surgery has defined cosmetic surgery as a subspecialty of medicine and surgery that uniquely restricts itself to the enhancement of appearance through surgical and medical techniques . It is specifically concerned with maintaining normal appearance, restoring it, or enhancing it beyond th...
The pancreasderived hormone insulin and the liversecreted hormones igf1 and 2 exert signalling effects by binding and activating their congeneric receptors: ir and igf1r . Although igf1r exists as a single isoform, ir is found in two distinct isoforms: ira (exclusion of exon 11) and irb isoform (inclusion of exon 11). ...
This is due, in part, to the realization that any reasonable model of the structure of a flexible protein must include a description of the thermally accessible states of the protein as well as the relative stability of each state . This information is quite difficult to obtain in practice because the set of ensembles ...
Multifocal intraocular lenses (iols) were designed to correct distance and near vision, and their effectiveness in achieving this has been demonstrated before . In contrast to refractive iols, diffractive iols are independent from the pupil diameter and provide a better near vision but demonstrate more disturbances in ...
The prevalence of diabetes is rising worldwide and is expected to reach the devastating number of 439 million by the year 2030 from 285 million in 2010 . This huge elevation is attributed to an escalating tendency towards sedentary lifestyle and westernized choice of diet, leading to obesity . Furthermore, the age of o...
To show the extent to which social and health care services are integrated across european home care systems . Different disciplines / providers from different organisational settings, which may be financed differently, provide care at the clients' home . Furthermore, client's access to care may be organised in various...
The valencia high dose rate (hdr) applicators, hereafter in the text vlcapp, are accessories of the micro - selectron hdr afterloading system (nucletron bv, veenendaal, the netherlands). The applicators are cup - shaped and tungsten shielded to limit the dose to the irradiation area and they are intended to treat surfa...
Multiple unerupted teeth are an uncommon condition in which there is more or less permanently delayed eruption of teeth . If the condition occurs due to endocrine dysfunction, proper treatment may result in the eruption of teeth or if associated with cliedocranial dysplasia, then there is no known therapy . In impacted...
H. kikutani (osaka university, osaka, japan). As control mice, cd40 or c57bl/6 mice lcmv (we strain) was grown on l cells at a low multiplicity of infection . R. zinkernagel (university of zrich, zrich, switzerland). Influenza virus (strain pr8) was originally provided by dr . J. pavlovic (university of zrich) and grow...
An episode that is frightening to the observer and is characterized by some combination of apnea (central or occasionally obstructive), color change (usually cyanotic or pallid but occasionally erythematous or plethoric), marked change in muscle tone (usually marked limpness), choking, gagging, or coughing (1, 2). This...
Over the past two decades, global iodine nutrition status has markedly been improved . According to the international council for control of iodine deficiency disorders (iccidd), the number of iodine deficient countries was decreased from 54 countries in 2003 to only 32 countries in 2011 [14]. Iodine deficiency causes ...
Semiconductor gas sensors offer good advantages with respect to other gas sensor devices due to their simple implementation, low cost and good reliability for real - time control systems [1 - 3]. Among them, zno, wo3 and sno2 have widely been studied . Tungsten oxide (wo3) is a wide band gap, n - type semiconductor tha...
Interest in the study of multisensory perception has grown dramatically over the last decade or so (see bremner, lewkowicz, & spence, 2012; calvert, spence, & stein, 2004; stein, 2012, for reviews). One particularly fascinating area of research interest involves the study of those interactions between touch / haptics a...
As invited guest editor for this mini - hot - topic collection of review manuscripts, i have had the honor of having a collection of world - experts in the pharmacologic management of atrial fibrillation (af) assemble for you, the readers, a timely collection of manuscripts that describe not only where we are with the ...
Diseases transmissible between humans and animals are one of the major public health problems in many countries . The cause of disease is an obligatory intracellular parasite with a worldwide spread called t. gondii (1). It is one of the most prevalent apicomplexan parasites found in various animal species and humans ....
Two major reforms occurred in the health system: establishment of primary health care (phc) and integration of medical education with the former ministry of health to create the ministry of health and medical education (mohme) (2). Both of these events were great achievements in the area of health promotion and improve...
Pterygium is an abnormal fibrovascular tissue extending on the cornea which is a degenerative and hyper plastic disorder . A stromal overgrowth of fibroblast and blood vessels is accompanied by an inflammatory cell infiltrate and abnormal extracellular matrix accumulation . Recently authors have focused on ultraviolet ...
Orthostatic hypotension (oh) is a common clinical problem among older adults, which affects nearly 25%30% of this population.1,2 common comorbidities, such as diabetes mellitus (dm), dehydration, and malnutrition, and frequent use of diuretics, antihypertensive drugs, levodopa, and benzodiazepines might lead to oh3 tha...
Human papillomavirus (hpv) infections manifest as both cutaneous and anogenital diseases in hiv - infected patients [1, 2], with a variety of skin lesions, both benign and malignant, including common warts, epidermodysplasia verruciformis - like lesions, non - melanoma skin cancers, and the giant condyloma of buschke a...
Mydriatics have a broad range of applications in ocular examination and treatment to allow for pupil dilatation and/or cycloplegia . In clinical practice, these agents are used to achieve cycloplegia before refraction examination; to achieve pupil dilatation before fundus examination, surgery, and angiography; or to pr...
With increasing globalisation, people all across the world tend to form common concepts of beauty, disregarding the ethnic concepts of attractiveness . Chubby cheeks were once considered desirable in an indian scenario, reflecting the overall health status of not only the individual but the family as a whole . With inc...
Rapid changes in the global environment have caused tremendous stress to many people, and in several cases has resulted in mental disorders or mental illness . Anxiety is one of the mental disorders caused by worries, fears, and tension . Mental disorders can influence physical or mental health, and also affects social...
Establishing thin solid films with well - defined morphological and/or crystallographic properties is of key interest in various fields of fundamental and application - directed research, examples including pharmaceutics, organic electronics, and colloid science . In all of these fields, the control over the solid - st...
Indwelling intravascular devices, which are becoming integral components of modern medical practice, are associated with the high incidence of nosocomial bloodstream infections especially in intensive care patients, those receiving chemotherapy and those dependent upon haemodialysis . Central venous catheters (cvcs) ac...
Glomus tumors are rare mesenchymal neoplasms composed of modified smooth muscle cells, closely resembling perivascular glomus bodies, with an occurrence of 1% among all soft tissue tumors . Glomus tumors are mostly found in distal extremities, but have been reported in the gastro - intestinal (gi) tract . The most comm...
An 18-year - old male came to mamata general hospital in january 2010 with a history of restricted outward movements of the eyes, inability to form facial expressions and to completely close the left eye, along with associated limb deformities, and inability to completely close the mouth, present since childhood . He h...
The study population consisted of individuals who had a comprehensive health examination at baseline (2003) and were reexamined 5 years later (2008) at kangbuk samsung hospital, college of medicine, sungkyunkwan university, south korea . Initially 15,638 participants were identified and 416 were excluded for having typ...
Diseases of breast, with their uncertain causes and confusion of treatments, have intrigued physicians and medical historians throughout the ages . As an appendage of the skin it may be difficult for the patient because of the anxiety associated with her underlying fear of a breast malignancy, and it may be difficult f...
The patients often suffer from metabolic disorders or even develop metabolic syndrome (ms) despite manifesting anovulation and signs of hyperandrogenism, such as hirsutism and acne . Disturbance of carbohydrate metabolism, which is manifested by insulin resistance (ir) and/or compensatory hyperinsulinemia, is now known...
The success of applying an antiangiogenic agent avastin in clinical settings for cancer treatment provided the first set of evidence to support the hypothesis that inhibition of tumor neovascularization can bring significant benefit to cancer therapy . Because neovascularization under either physiologic or pathologic c...
Complications of salmonella typhi, besides gastrointestinal system, involve nervous system, bone marrow, kidneys, and heart. [13] empyema thoracic due to s. typhi is a rarely reported complication, and most of the case reports are from adults . Although respiratory symptoms are common, empyema thoracic is a rare occurr...
Completely isolated duplication cysts (cidc) involving the gastrointestinal tract are a rare variant of enterogenous duplication cysts . Coexistence of a cidc with a classic enterogenous duplication cyst has been reported only once earlier in the literature and an acute presentation of a cidc has not been reported earl...
Cure rates for advanced ovarian cancer are low, regardless of the type of treatment received . An average 5-year survival rate of 10% (0 - 15%) has been obtained with abdominal radiation therapy 1 - 4, and response rates vary from 3 to 30% with chemotherapy 5 - 9 . Recent multivariate analyses of prognostic factors sug...
Use of high - dose - rate brachytherapy (hdr) for prostate cancer has increased over the last decade (1). Hdr brachytherapy has produced excellent outcomes as either monotherapy (2) or as a boost in combination with external beam radiation therapy (ebrt) (3, 4). The groupe europen de curietherapie (gec) european societ...
Abdominal tuberculosis (tb) is not uncommon in the developing world, but isolated colonic tb is rare; it has been estimated that 2 - 3% of patients with abdominal tb have isolated colonic involvement (1). It also accounts for 10.8% of all gastrointestinal tb with the commonest affected site being the transverse colon, ...
Arsenic exposure with drinking water and the food is very common in west bengal particularly in rural parts of north and south 24 parganas district . Around 150 million people are at risk from arsenic contaminated ground water in the combined areas of west bengal and its neighboring country bangladesh . While toxicolog...
The hepatitis c virus (hcv) has infected 4 million people in the united states and 170 million people worldwide . Hcv infection is cleared in 25% of cases (1,2), and in the rest results in chronic infection . A recent study (3) estimated that lifetime hcv - associated mortality is around 1 in 8; a much larger number (a...
The online version of this article (doi:10.1007/s00134 - 010 - 2128 - 6) contains supplementary material, which is available to authorized users . Hypovolemia is a major complication occurring in numerous clinical scenarios involving civilian, combat and disaster field traumas, surgical injuries, and intensive care set...
Between january 2012 and december 2014, blood samples and renal biopsies were collected from 30 patients who had been newly diagnosed as having mpoaav, and each patient gave written informed consent to participate in the clinical study . The titre and affinity of serum mpoanca taken before the start of the therapy were...
Multiple sclerosis (ms) is one of the most common chronic neurological diseases, affecting between 1 in 500 to 1 in 1500 people in australia, europe, and america [1, 2]. The condition is characterised by neuronal demyelination and inflammation, leading to axonal injury as the disease progresses [2, 3]. Ms has several f...
We estimated the weekly number of cases of gbs and associated healthcare needs for 3 scenarios: 1) in the absence of zika virus transmission; 2) in an average week during zika virus transmission; and 3) during the peak week of zika virus transmission (table). The population of puerto rico in 2015 was estimated at 3,474...
Homonymous hemianopic and quadrantanopic field loss are widely considered to be incompatible with safe driving in many jurisdictions across the world . However, a number of recent reports have challenged this assumption, suggesting that some individuals with homonymous field defects have the potential for safe driving ...
This study was conducted using formalin - fixed, paraffin - embedded tissue samples obtained from 170 ptc patients who underwent thyroid surgery at kangdong sacred heart hospital between january 2006 and december 2007 . Among the 170 patients, 84 had available data including the preoperative serum thyroid autoantibodie...
Infections have been commonly implicated in lupus relapses and in some cases as initiating the diagnostic work up of systemic lupus erythematosus (sle). A previously described association in literature is that of salmonella typhi bacteremia and cryptococcal neoformans meningitis occurring concurrently with the first pr...
Primary percutaneous coronary intervention (pci) is the preferred reperfusion strategy for patients presenting with stsegment elevation myocardial infarction (stemi).1, 2 this is somewhat more straightforward when patients present directly at the nearest pcicapable facility, but in regions that are sparsely populated a...
Electrical storm (es) is a dramatic and life - threatening syndrome which is defined by three or more sustained episodes of ventricular tachycardia (vt), ventricular fibrillation (vf), or appropriate shocks from an implantable cardioverter - defibrillator within 24 h (13). This pathology is may cause fatal arrhythmia i...
Pigment epithelium - derived factor (pedf) is a 50 kda secreted glycoprotein and a member of the serpin superfamily with no demonstrable protease inhibitory activity . Pedf is associated with several biological processes due to its antiangiogenic, anti - inflammatory, anti - oxidative, neurotrophic, and neuroprotective...
Convergence insufficiency (ci) is a sensory motor anomaly that is characterized by an inability to accurately converge or sustain convergence at near, which can cause substantial symptomatology during reading and near visual tasks [1, 2]. It is a common vision anomaly usually characterized as a binocular vision disorde...
Abnormal head size (very small or very large) at birth or in early infancy is a strong indicator of intrauterine disturbances accompanied by fetal growth restriction, maternal and fetal malnutrition, as well as being a precursor to diverse neurodevelopmental disorders, such as, cerebral palsy, epilepsy, mental retardat...
Lifestyle changes can affect blood pressure; in this regard, beneficial effects of nutrition on health and blood pressure control have been reported (1) in the literature . Accordingly, nutrition is regarded as one of the most important aspects of life style for controlling blood pressure (2, 3). Also, nutrition is con...
In the past decade, with international support, tanzania has made substantial efforts to expand water supply and sanitation infrastructure . Despite the increasing coverage, the child mortality rate in 2009 (under age 5) was 108 for every 1000, and nearly 13% of those deaths were attributed to diarrheal diseases . Even...
Periprosthetic joint infections (pjis) remain a challenge for orthopaedic surgeons to treat, and remain a leading cause of failure of both primary and revision total joint arthroplasty (tja). 1 with a reported incidence of 0.5%-7.0%, pji is associated with a high morbidity and a mortality rate ranging from 2.7%-18.0%.1...
Leiomyomas arise in the reproductive age group and are composed of interlacing bundles and fascicles of smooth muscle cells . They can also arise in the cervix, broad ligament, retroperitoneum, and mesentery . Leiomyomas with unusual growth patterns include benign metastasizing leiomyoma, retroperitoneal leiomyomas, pa...
These injuries are usually combined with other injuries (e.g., brain and thoracic injuries) as a result of motor vehicle accidents or falls . The clinical and/or radiographic findings vary after a cervical spine injury depending on many factors, such as the severity of the injury, the presence of spinal cord injury, th...
Zirconium dioxide (zro2), also called zirconia, is characterized by superior mechanical properties such as high flexural strength, relatively low elastic modulus, and high fracture toughness as compared to other ceramic materials.12 yttria (y2o3) is added to zirconia to improve its mechanical properties, and yttria tet...
Plants of the genus allium are known for their production of organosulfur compounds, which possess interesting biological and pharmacological properties . Among these, garlic (allium sativum) is one of the most widely used ones . When extracted and isolated, these compounds exhibit a broad spectrum of beneficial effect...
This growth was affected by a number of factors, including an increase in the number of enrollees, higher provider payments, and changes in medicaid financing arrangements . States responded to these changes in a variety of ways, including taking advantage of special financing arrangements, modifying the service delive...
Gene panel sequencing in a cmml patient without any detectable genetic abnormality by conventional genetic studies identified four concurrent somatic mutations in three genes . Gene panel mutation analysis is a rapidly emerging clinical tool to demonstrate the clonality in hematologic malignancies, and to identify the ...
Asthma is a chronic, inflammatory lung disease characterized by symptoms of cough, wheezing, shortness of breath, and chest tightness that occur in paroxysms and are usually related to specific triggering events . Asthma in children, estimated to cost $3.2 billion per year, accounts for 14 million missed school days an...
Radiotherapy is an important modality in tumor combinational treatment and is used for treating multiple tumors with good therapeutic effects . Moreover, when radiotherapy is combined with chemotherapy, surgery or other targeted therapies, treatment efficiency is improved and recurrence and cancer death rates are reduc...
With nanotechnology becoming widely used, there is an increasing demand for rapid, parallel fabrication strategies for nanoholes and nanopillars . Some applications that require repetitive uniform nanoholes and nanopillars over large area are photonic crystals, memory devices, nanofiltration, solar cells, artificial ki...
Plants are among the few organisms that can synthesize all the required metabolites from inorganic ions, water and co2 using the energy captured from the sun . Hydroponics is a method of growing plants that takes advantage of this fact by providing all of the nutrients, in their inorganic form, in a liquid solution wit...
Chronic diseases, such as cardiovascular diseases (cvd), cancer, and age - related diseases, have long been considered among the most important global public health issues . Clarifying the common pathological process of these diseases or statuses is a crucial step toward providing early prevention and treatment . A gro...
Peptic ulcer bleeding continues to be an important cause of non - variceal upper gastrointestinal bleeding . The endoscopic therapy is well - accepted as the first - line management tool for bleeding peptic ulcer . Endoscopic therapy for a bleeding peptic ulcer generally includes injection therapy, thermal coagulation ...
Radical prostatectomy (rp) is a challenging operation that demands high levels of surgical expertise and experience . Rp can be performed with open or with minimally invasive laparoscopic or robot - assisted approaches . Vesicourethral anastomosis is the most technically challenging part of the procedure and can be per...
Intravascular large b - cell lymphoma (ivl) is a rare type of extranodal lymphoma with an aggressive clinical course characterized by the proliferation of lymphoma cells within the lumen of small vessels with no or only minimal involvement of the parenchyma . The signs and symptoms of the disease are heterogeneous and ...
Large dna viruses of bacteria and eukaryotes have complex life cycles with several distinct phases that involve diverse virus - host interactions . An array of regulatory systems mediate activation or repression of expression of specific batteries of viral genes that are required at different phases of the life cycle ....
In 2009, more than 85,000 students earned undergraduate biology degrees at colleges and universities in the united states . These students represent the second - largest single population of science majors at american colleges and universities, trailing only psychology (national science board, 2012). Furthermore, in 20...
Onychomycosis is one of the most common nail disorders, accounting for nearly 50% of them . Within skin diseases it has a prevalence of 0.44% with a worldwide prevalence ranging from 2 to 50% . The vast majority of cases are caused by dermatophytes as t. rubrum (7187%) or t. mentagrophytes var interdigitale (922%). The...
While ebm's view that scientific evidence trumps practitioners experiences and intuition has moderated somewhat in light of recent criticisms, in everyday practice, it becomes easy to consider evidencebased guidelines as overly prescriptive [7, 14, 19, 20]. Clinical circumstances often are increasingly complex and unce...
Human embryonic kidney cells (hek 293) were maintained in an incubator with 95% air5% co2 in dulbecco's modified eagle's medium, plated on glass coverslips and transfected after 10 h by a calcium phosphate dna co - precipitation method with cdnas coding for the enhanced green fluorescence protein (egfp) and for the rat...
Cytarabine is a pyrimidine antagonist used in the treatment of haematological malignancies . In combination with other chemotherapeutic agents, it is indicated amongst others for remission induction in acute myeloid leukaemia (aml). Nevertheless, cytarabine is known to provoke various adverse effects, including bone ma...
A lack of signs, symptoms, and radiographic findings specific to foraminal stenosis may lead to failed treatment 4 5, and may be the cause of pain in up to 60% of patients who remain symptomatic postoperatively 4 . Initial treatment for symptomatic foraminal stenosis is centered on aggressive conservative methods, incl...
Only a few reports have been published to date reporting deletions in the (14) (q11.2q13) region. [13] each report has contributed in widening the spectrum of clinical features associated with the deletion . Here, we discuss the first case with this deletion that is present in the mosaic form and associated with anopht...
Incident reporting is one of the inexpensive and reliable methods, through which errors in medical care are discovered . It has also been used as a tool for quality assurance . Other commonly used methods to identify errors in medical management include retrospective chart review and computerised surveillance . Adverse...