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Tendinous xanthomas are caused by impairment in lipoprotein regulation, which results in accumulated cholesterol deposits in the tendons, ligaments, or periosteum . The nodules are most often found over the achilles tendons, hands, and the extensor surfaces of the elbows and knees . These slow - growing nodules are fir...
Protein expression and purification the prseta vector containing gcamp2 was a kind gift of karel svoboda (janelia farm research campus, howard hughes medical institute). Briefly, bl21(de3) cells containing prseta harboring gcamp2 or gcamp2 mutants were grown in zym-5052 medium (18) for 48 h at 25 c with shaking at 200 ...
The mortality related to gastric cancer is decreasing because of the dissemination of gastric cancer screening programs as well as advances in surgical techniques, chemotherapy, and radiotherapy . There is a national mass screening program for gastric cancer in korea, which recommends biennial screening with gastroscop...
These procedures range from basic excision to sliding flaps or rotation of the conjunctiva, with and without adjunctive external beta radiation, excimer laser and/or the use of topical chemotherapeutic agents such as mitomycin c. because of serious complications of the adjunctive procedures,123456 most corneal surgeons...
A 14-year - old girl was referred to our clinic because of her growth retardation and scoliosis . She had been born via caesarian section at 38 weeks with a birth weight of 1,500 grams, and she had been observed in the neonatal intensive care unit for three days . Her laboratory values obtained at the second day of bir...
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
The issue of being overweight and obese is becoming an increasingly prevalent problem in both developed and developing world, and it is one of the most serious public health challenges of the 21 century . During the past two decades, the prevalence of obesity in children has risen greatly worldwide and elementary schoo...
Hypoparathyroidism is rare in childhood, characterized by inadequate parathyroid hormone (pth), resulting in hypocalcemia and hyperphosphatemia and also in some cases, calciuria and 25-oh vitamin d deficiency . Hypoparathyroidism can be transient, inherited, or acquired, caused by inability to synthesize or secrete pth...
Aggregation - induced emission (aie) is an important photophysical phenomenon associated with chromophore aggregation, first discovered in 2001 for 1-methyl-1,2,3,4,5-pentaphenylsilole . In this process, these so - called aiegens have found numerous technological applications, for example, in optoelectronic materials, ...
Thirty - three right - handed participants (men = 20) who met the criteria for pd were recruited . Exclusionary criteria for enrollment in this study included use of the left hand for writing, history of learning disabilities, history of other or concurrent neurological disorders, and history of major psychiatric disor...
Obesity is a complex, multifaceted condition characterized by excess or abnormal deposition of body fat that may jeopardize an individual's health . It is caused by the interplay of many complex biological, psychological, socio - cultural, environmental and economic factors . Almost all developed and developing countri...
Vital tooth bleaching using carbamide peroxide is a safe, well accepted and an increasingly popular procedure for the treatment of surface and intrinsic staining of teeth. [13] clinicians should be aware of the outcome of the bleaching treatment and the interactions with further dental treatments, especially additional...
Colorectal cancer (ccr) holds the third place in incidence and the fourth place among the most common causes of cancer death worldwide . Detection in the early stages of colorectal cancer, detection of adenoma in apparently healthy subjects, in whom the disease progresses asymptomatically, through screening is resultin...
Although infantile wmi was named pvl, it seems like that wmi is widespread including periventricular, subcortical and callosal white matters, and internal capsule [12 - 15]. Injury of white matter usually predominates, however gray matter areas, such as the cerebral cortex, thalamus and basal ganglia, are also affected...
Treatment for the correction of presbyopia has continued to be the focus of considerable research . Typically affecting people from 40 years of age, the loss of near visual acuity is often attributed to increased lens nucleus hardness and subsequent inability of the lens capsule to compress the lens to a more convex st...
Hydatid disease, although rare, is still endemic in many countries, representing an important public health problem . Reviews show that the most frequently involved organs are the liver (55%) and lungs (40%). Rarely, hydatid disease may be found in the spleen (1.8%), kidneys (1.4%) bones (0.1%) or other sites (1.7%). A...
The cumulus - oocyte complex is a structure characteristic of higher mammals, resulting in an interesting symbiosis between an oocyte (germline) and surrounding cumulus cells (somatic) (1). Cumulus cells share an intimate communication with the oocyte through gap junctions and paracrine factors (2), allowing a bidirect...
In the last 15 years, the interactions taking place between bone and other organs, most notably the brain, have become a topic of growing interest . One reason for this interest is that the study of these interactions has provided a better understanding of the regulation of bone mass accrual and energy metabolism [24]....
Hypertensive encephalopathy (he) is a life - threatening condition characterized by severe hypertension, altered mental status, headache, dizziness, visual changes, and seizure . The condition is reversible if promptly diagnosed and treated, but if treatment is delayed it may progress to coma or death . Because the les...
We have been studying a model for the origin of cellular life in which a membranous compartment capable of self - replication encapsulates a functional and genetic biopolymer that is also capable of self - replication . The processes of protocell membrane growth and division are thought to have relied on the self - ass...
Several previous studies point to the central role of mitochondria in pd: reduced complex i activity [1, 2, 3, 4, 5], reduced mitochondrial membrane potential (m) along with increased production of reactive oxygen species (ros) [6, 7], alterations in mitochondrial fission - fusion events [8, 9], and defects in mitochon...
When radiotherapy is used with curative intent, the possibility of late complications in the irradiated tissues must be considered . The spectrum of malignant neoplasms secondary to radiation of head and neck tumors is wide . It includes skin, thyroid, and bone neoplasms . Because radiation fields for npc may include t...
Cell lines and reovirus: seven established canine mgt cell lines (cip - p, cip - m, ctb - p, ctb - m, chm - p, chm - m and cnm - m), 5 canine osteosarcoma cell lines (abrams, d17, gracie, mackinley and moresco) and six canine malignant melanoma cell lines (cmec1, cmec2, kmec, lmec, cmgd2 and cmgd5) were used in this st...
Falls among older people remain a major public health problem and one that continues to contribute to growing use of health care services such as emergency department and hospital inpatient care,1 despite a strong evidence base for prevention developed over the past 15 years.2 the most recent cochrane review of fall pr...
Ckd - mbd is a systemic syndrome defined as a systemic disorder of mineral metabolism that can lead to bone and cardiovascular abnormalities .' The syndrome consists of abnormalities in laboratory values, abnormal bone metabolism, and vascular calcification . Bone biopsy samples obtained from ckd patients demonstrate a...
Packaging of dna into a higher - order structure called chromatin has an enormous impact on eukaryotes . It influences all processes that occur on dna, such as replication, repair and transcription . Enormous progress has been made in recent years to characterize the factors that interact with chromatin . Chromatin rem...
Each mhs records patient information in a national database, which includes information on age, postal code, date of symptoms, complications, hospitalization, and source of infection . Notifications of measles cases were used to assess medical costs and productivity losses (technical appendix). Information on additiona...
We investigate polycrystalline ni films (550 nm thick unless otherwise stated) thermally evaporated, or sputtered onto various substrates chosen to act as solid carbon sources: highly orientated pyrolytic graphite (hopg), tetrahedral amorphous carbon (ta - c), and nanocrystalline diamond . Hopg(0001) substrates (mikrom...
Wilson's disease is an autosomal recessive disorder caused by mutations in the atp7b gene . Wilson's disease can cause distal renal tubular acidosis (rta), which may lead to metabolic bone disease . A 16-year - old boy presented with history of fullness in left hypochondrium of the abdomen associated with early satiety...
Congenital heart disease (chd), a common and serious birth defect, affects 8 per 1000 live - born infants(1). Although advances in pediatric cardiology and cardiac surgery have greatly improved outcomes in infants with chd, recent data indicate that chd still accounts for 21% of all deaths in the first month of life an...
Electrolytes are measured in the clinical laboratories in both serum and whole blood sample received for arterial blood gas (abg) analysis . Although the routine practice is to measure electrolytes in serum, it takes relatively more time due to requirement of separation of serum . Emergency and critical care physicians...
The incidence of skin cancer is increasing worldwide, possibly arising from an ageing population and increasing sunlight exposure . Bcc most often arise in areas of long - term sun exposure with a high predilection for the head and neck area . Classical clinical features include raised and rolled edges, pearly central ...
Complementary and alternative medicine (cam; b chng y t di y xu) are a group of management practices that are not part of conventional western medicine . In us, 40% of parkinson's disease (pd) patients use some form of cam during the course of their illness, while in korea, it is as high as 76% . Though using it for lo...
Multiple sclerosis (ms) is a progressive autoimmune inflammatory and demyelinating disease of the central nervous system (cns). The pathological hallmarks of ms are white matter demyelination, inflammation, axon damage, and blood - brain barrier (bbb) disruption [13]. The etiology of ms is still not clear, but ms is cl...
Although, brushing teeth twice a day and daily flossing is highly effective in plaque reduction, over 50% of adults have gingivitis on an average of 3 to 4 teeth2 . The considerable prevalence of gingival inflammation within the general population suggests that most patients practice inadequate oral hygiene, particular...
Bilirubin (br), long considered to be exclusively a toxic waste product, has recently been recognized as an immune - modulatory metabolite able to modulate cd4 + t lymphocyte (tl) function [13]. Particularly, we recently reported an immune - modulatory role of conjugated br (cb) in hepatitis a virus (hav) infection . B...
Studies on the physiology of breastfeeding revealed the presence of the two adipokines, leptin and adiponectin, hormones, such as igf - i, ghrelin, and more recently obestatin and resistin in mother's milk (table 1). Human milk is a complex biological fluid: leptin and ghrelin are synthesized and secreted into breast m...
In a 61-year - old man with child's class a hepatitis b - related liver cirrhosis, a 2.3 cm - sized mass was detected in couinaud's segment iii of the liver upon a routine screening us which was performed as a surveillance of the hepatocellular carcinoma (hcc) (fig . 1a). On a subsequent contrast - enhanced ct, the mas...
Double atrial septum is extremely rare congenital anomaly, which has double - walled atrial septum that distinguishes midline interatrial chamber between the two atria.1)2) this interatrial space sometimes distinguished from left atrium by septum primum, otherwise from right atrium by accessory septal structure.2)3) in...
It is important to seal the root canal system three dimensionally in order to overcome the problems associated with microleakage, which may eventually lead to treatment failure . Microleakage can occur apically and coronally as a result of improper seal between the core obturating material and the root canal dentin . T...
Leukemic retinopathy refers to numerous, abnormal fundoscopic findings that stem from complications of leukemia, such as anemia, thrombocytopenia, and hyperviscosity.1,2 the most prevalent of such findings include intraretinal hemorrhages, cotton - wool spots, and white - centered hemorrhages . These hemorrhages are ty...
Il-6, produced by tumor - associated macrophage, is an important mediator that promotes tumor growth [1, 2]. Although there was evidence supporting a role in t - cell activation and trafficking, il-6 within the tumor microenvironment is generally considered as a malevolent player that promotes tumor progression . By ac...
In europe, the breast cancer incidence is 464.000 cases representing the most common cause in women . Most of them are treated following the oestrogens receptors (er), progesterone receptors (pr), and epidermal growth factor receptor type 2 (her2) status . The human epidermal growth factor receptor 2 (her2) was first d...
A 23 year female had chronic pain in upper abdomen since 3 years with acute exacerbations off and on, once in 4 to 6 months, lasting for 8 days responding to analgesics . On examination, routine sonography showed moderate splenomegaly 178 mm in craniocaudal direction, with a large mass at the lower pole, which was pred...
The anti - neutrophil cytoplasmic autoantibodies (anca)-associated vasculitides (aavs) comprise a group of diseases characterized by necrotizing vasculitis of small vessels, frequently with involvement of the kidneys and lung.1 genetic and environmental factors are involved in their etiopathogenesis, with a possible ro...
Education authorities and thinkers view curriculum as the most essential element in the education system . This area is looked upon as one of the youngest in human science, creating concepts and changing at such a fast pace within its realm that makes it difficult or even impossible to mark the boundaries . Eisner view...
Major resection of a cirrhotic liver can result in hepatic decompensation and even fatal hepatic failure . To minimize such operative risk, hepatic reserve is assessed preoperatively, including both qualitative and quantitative aspects of liver function . Yet even when these parameters appear to permit liver resection,...
Bisphenol a (bpa) is a widely used chemical in the production of plastic food containers in many consumer products and of epoxy resins in dental fillings . Exposure to bpa is very common in almost all us adults, asian population, and about 80% of thai population . Recently, this chemical has received much attention for...
Diaper dermatitis (dd) is the most common cutaneous diagnosis in infants, particularly at 1 - 15 months of age . Most cases are associated with the yeast colonisation of candida or diaper dermatitis candidiasis (ddc). It is an irritating and inflammatory acute dermatitis in the perineal and perianal areas resulting fro...
Primary hyperparathyroidism (phpt) is one of the most common endocrine diseases with prevalence rates of about 3 per 1,000 in the general population and up to 1 per 100 in the elderly . The chances of developing phpt increase with age, and patients are most often diagnosed in the sixth and seventh decades of life . Cha...
Nephrotic syndrome may occur in a wide variety of clinical settings such as diabetes mellitus, amyloidosis, systemic lupus erythematosus, membranous nephropathy, focal glomerulosclerosis, as well as minimal change disease (mcd). It is generally recognized that mcd accounts for up to 15% of all cases of adult nephrotic ...
Chondroblastoma is a rare, benign bone tumor that represents 12% of all primary bone tumors and approximately 5% of benign bone tumors 1, 2 . It most commonly occurs in the femur, humerus, and tibia 3, 4, 5 but has also been described in flat bones such as the scapula, patella, sternum, and the bones of the skull . Whi...
Sclerosing adenosis is a form of adenosis in which there is an expansion of terminal duct lobular units (tdlu) due to proliferation of glandular components, accompanied by stromal proliferation which is usually dense and hyalinized with resultant compression and distortion of glands . Though it is often found as a micr...
This randomized clinical trail study was performed on 150 patients in ophthalmic research center of labbafinejad medical center (tehran, iran) during two years ending in 2007 . Considering 90% power for detection of a 0.2-logmar difference (equal to 2 snellen lines) in visual acuity and being significant at the two - s...
Despite a substantial decline in the incidence of early onset group b streptococcus (gbs) infections in the newborn, gbs remains an important cause of morbidity and mortality in the newborn period . Clinical trials have demonstrated the effectiveness of antibiotic prophylaxis administered during labor to women colonize...
Subclinical hypothyroidism (sch) is characterized by increased serum thyroid stimulating hormone (tsh) and normal serum free thyroxin (ft4). . In our country, prevalence of sch varies from 2.8% in south india to 14.3% in northern part of the country . Sch usually does not have any symptoms or sign in nonpregnant women ...
Although mental retardation in children has been known since biblical times, it was not before the nineteenth century that the diagnosis of mental retardation had therapeutic implications1 . This movement for detection of mental retardation at the earliest possible time was based on a belief in the benefits of early in...
Cardiogenic shock is the leading cause of death for patients with acute myocardial infarction who reach the hospital alive . It affects about 6 to 8% of patients with acute myocardial infarction . Despite the advantages of early intra - aortic balloon pump (iabp), fibrinolysis, percutaneous coronary intervention or cor...
Cysticercosis is an infection by the larval stage (cystcercus cellulosae) of the cestode, taenia solium (pork tape worm). It occurs especially in those individuals who live in the endemic areas . After gaining entry into the body, the larva become encysted and may lie in subcutaneous tissue, striated muscle, vitreous h...
Intensive care unit patients are at greater risk to acquire nosocomial infection because of invasive procedures, prolonged hospital stay, high antibiotic use, cross transmission among patients and staffs, and inadequate infection control procedures which predisposes icu as a suitable place for emergence and spread of n...
Fibroadenomas are among the most common tumours of the female breast, occurring most frequently in women of child - bearing age, especially those under 30 years . Most present as single mass, however the presence of multiple fibroadenomas can be seen in 1520% of patients . It has been reported that the average number o...
Hocl solutions: an hocl solution, slightly acidic hypochlorous water (sahw) containing 50 ppm chlorine, was prepared by a well clean te hi - clo soft acidic water generator (osg co., ltd ., osaka, japan) in our laboratory with normal tap water on the day of use . Hocl solutions containing 100 and 200 ppm chlorine were ...
Bumps and scrapes are a part of every child's life . However, for unfortunate children with hemophilia, the dental traumas of childhood are reason for extra concern . Hemophilia results due to deficiency in either factor viii or ix due to an aberrant gene makeup . With an indian population of 1.2 billion, there are aro...
Buruli ulcer is a debilitating human skin disease caused by mycobacterium ulcerans [1, 2]. This infection is a neglected emerging disease that has recently been reported in some countries as the second most frequent mycobacterial disease in humans after tuberculosis [3, 4]. Other cases have been reported in asia, austr...
Systemic lupus erythematosus (sle) is an autoimmune disease characterized by the production of autoantibodies to nuclear antigens . The severity, prognosis, and manifestations of the disease are highly variable between patients . Involvement of the respiratory, cardiovascular, and central nervous systems can also occur...
The success of dental implants depends on the manner in which stresses are transferred to the surrounding bone . Load transfer from implants to surrounding bone depends on the type of loading, the bone to implant interface, the length and diameter of the implants, the shape and characteristics of the implant surface, t...
Pleomorphic undifferentiated sarcoma (also called as pleomorphic malignant fibrous histiocytoma) is an extremely rare tumor of the urinary tract in adults . In view of the rarity of its presentation, herein we present a case report and literature review of primary pleomorphic undifferentiated sarcoma of urinary bladder...
The heterotopic pancreas is defined as a pancreatic tissue found outside the eutopic pancreas without anatomic or vascular connections between them . It is not uncommon with an incidence of approximately 0.5 - 13.7% in autopsy studies and 0.5% in upper abdominal laparotomies (1). It can be found anywhere in the gastroi...
Uremic bleeding reflects a complex disorder of hemostasis and, until recently, the cause of the uremic defect in primary hemostasis has been obscure . But two recent clinical studies suggested a role for factor viii in the hemostatic defect of uremia . These studies demonstrated that maneuvers that increased the level ...
The preservation of a healthy periodontium is critical for the long - term success of a restored tooth . Dentists must constantly balance the restorative and esthetic needs of their patients with periodontal health . One factor that is of particular importance is the potential damage that results in the periodontium wh...
Most persons with stroke place more weight on their non - affected leg and therefore have an asymmetrical posture . Transferring their body weight to the affected leg is a more difficult task than transferring it to the non - affected leg2,3,4,5 . Difficulty in transferring body weight is also seen in both high and low...
Haemoglobinopathies are genetic defect that results in abnormal structure of one of the globin chains of the haemoglobin molecule abnormal haemoglobin appears in one of three basic conditions; structural defects in the haemoglobin molecule, diminished production of one of the two subunits of the haemoglobin molecule (t...
Laparoscopic surgery is associated with a decrease of postoperative pain and surgical complications and a faster postoperative rehabilitation . This technique has also become the standard surgical technique for many pediatric interventions, previously realized by open laparotomy . The miniaturization of optical and dis...
His work was really a culmination of collecting relevant clinical and pathologic observations of the last century and a half . Each lobe is identified by a single orifice on the nipple papilla connecting to branching tree of ducts and hundreds to thousands of individual lobules in the periphery . He proposed that for m...
Temporomandibular disorders (tmds) share the common feature of being significantly more prevalent in women than in men . The female: male prevalence ratio for tmds is nearly 2:1 in the general population and can exceed 8:1 in clinical populations1 . Further, many authors have reported that the prevalence and severity o...
We identified genetic variability of mers - cov s genes among infected persons in south korea . These patients were identified by using sequences upstream of the envelope protein gene and open reading frame (orf) 1a in real - time reverse transcription pcrs (5) (table 1). Sequence obtained from the chinese centers for ...
The history of neutron activation analysis (naa) formally started in 1934, when george de hevesy and hilde levi demonstrated the feasibility of nuclear activation for element analysis in one of their many famous experiments, . For many reasons it remained a sleeping beauty until by the early 1960s a stormy development ...
Cd45.1 or thy1.1 congenic ot-1 tcr transgenic nave t cells were isolated using the cd8 untouched isolation kit (miltenyi biotech) plus biotin conjugated anti - cd44 . Cells were transferred into c57/bl6 (jackson laboratories) mice 1 day prior to infection . Recombinant listeria monocytogenes strains were generated that...
Stroke can lead to recurrent lower respiratory functions and worsening pulmonary fucntion, with increased morbidity and mortality1 . Impaired respiratory fucntion may be a consequence of weakness of the respiratory muscles and postural trunk dysfunction . Several studies consistently reported highter positioning of the...
It is caused by schistosoma mansoni that causes periportal fibrosis that results in portal hypertension . Despite extensive peri - portal fibrosis, this study was conducted in al ain hospital in the united arab emirates and sudan clinic in khartoum, sudan . Data was collected prospectively from all patients who had lap...
A well - established best practice in the care of patients with stroke is the early detection of dysphagia as it allows for immediate intervention thereby reducing morbidity, length of stay, and healthcare costs [13]. The essential first step to ensure early detection of dysphagia, and to prevent dysphagia - related mo...
Current treatment options for antipsychotic - induced hyperprolactinemia are limited (ie, decrease dose of existing antipsychotic, switch to a prolactin - sparing antipsychotic, dopamine receptor agonist) and carry a high risk of exacerbating psychotic symptoms or a relapse.1 this case report may provide a new strategy...
Obstructive sleep apnea (osa), a common disorder, is often asymptomatic, and the prevalence of patients with osa, who do not present clinical syndrome, might be as high as 2030% in the middle - aged population . These recurrent episodes of upper airway collapse usually are accompanied by oxyhemoglobin desaturation and ...
Celiac disease, popularly known as the allergy to wheat flour in medicine is marked by the term gluten enteropathy, or damage to the intestine caused by gluten . Celiac disease is essentially not a disease but a predisposition for the disease because only by intake of gluten causes the damages in the lining of the smal...
The feet support the body s weight and play the role of levers when an individual is performing work1 . The body weight normally falls on the center of the foot, and balance is maintained by the muscle activity of the foot2 . If the foot becomes diseased or deformed, the foot adapts to perform its functions under the c...
People s sex lives are part of the expression of a basic instincts are crucial to human life, and have a significant influence on individuals and society . As a catalyst for biorhythm, a healthy sex life lessens mental and physical exhaustion, brings relaxation and enriches the quality of life1 . The world health organ...
Pediatric urinary tract infections are a common clinical problem occurring in up to 8% of children between the ages of one month and eleven - years - old (1, 2). Recurrence of these infections may occur in up to 40% of these same children (3). Febrile urinary tract infections (uti) in infants may lead to renal scarring...
At different times during our respective childhoods, we both toured carlsbad caverns in new mexico . The darkness was incredible, engulfing absolutely everything . In our society, we rarely experience such profound darkness; every night, our homes, work places, and streets are brightly illuminated by the glow of electr...
Primary central nervous system lymphoma (pcnsl) is hematopoetic tumors that is usually restricted to the central nervous system5,7). It is well known that pcnsl presents as one or more discrete, well - enhancing lesions on magnetic resonance image (mri). Meanwhile, lymphmatosis cerebri refers to the extensive, diffuse ...
Deep brain stimulation (dbs) is an effective therapy for neuropsychiatric disorders, and there is a research need for small, wireless devices . A typical dbs system consists of three major components including an implantable pulse generator (ipg), electrodes, and a programmer . It is a signal generator which is implant...
Quality of health services is the most important factor in the success and sustainability of health organizations, thus increasing loyalty and customer satisfaction of provider organization (1). The quality of services, especially in institutions faced with high volumes of visitors, can be used as a crucial measure in ...
In the vertebrate head, multipotent progenitor cells give rise to crucial components of sense organs and sensory ganglia (schlosser, 2010; streit, 2007). They reside in the ectoderm next to the anterior neural plate, where they are induced by fgfs combined with wnt and bmp attenuation (ahrens and schlosser, 2005; brugm...
Computational modeling of protein structures has become an effective means of generating new biological information . Ideally, a structure prediction server would provide a simple, sequence in / structure out approach that generates a single best model for any given protein sequence . However, there is a wide variety o...
Pre - eclampsia can be quite serious as it can lead to various complications both for the mother and the baby . In fact, pre - eclampsia and eclampsia, severe forms of pih, are the leading cause of infant and maternal death in the united states there are genuine differences in the incidence of hypertensive disorders of...
Almost immediately after being funded, the center for biological and environmental nanotechnology (cben) found itself under intense scrutiny for their proposed research on the environmental and biological implications of nanomaterials . Even though they had designed the center to emphasize the applications of nanotechn...
Papillary thyroid carcinoma (ptc) is the most common form of the follicular - cell - derived carcinomas and comprises three quarters of all newly diagnosed thyroid cancers . The prognosis for ptc is usually excellent (reviewed in). Over the past 1015 years, several candidate genes have been studied in the development o...
Major depressive disorder (mdd) is a mood disorder commonly found among the elderly; it is characterized by a loss of pleasure, sadness, sleep disturbance, a poor sense of self, guilty feelings and cognitive impairment . The prevalence of late - life depression varies, but evidence suggests that mdd rates in community ...
People with severe short stature have been classified as those with normal ratio of trunk to limb length (proportionate dwarfism) and those with disproportionate development . Achondroplasia, the commonest form of short limb dwarfism, is associated with several bony changes in the face, neck and spine, and can have neu...