text stringlengths 0 868k |
|---|
A subclinical elevation of urinary albumin excretion, that is, microalbuminuria, has been associated with an increased risk of cardiac morbidity and mortality in reported population studies . Microalbuminuria was first introduced as a risk factor for chronic renal failure among patients with diabetes, and later was fou... |
In india, the first case of human immunodeficiency virus (hiv) was reported in 1986 in chennai . The country experienced a sharp increase in the estimated number of hiv infections, from a few thousand in the early 1990s to around 5.2 million adults and children living with hiv / aids in 2005 . In 1987, a national aids ... |
Data stream mining is the process of extracting useful information from continuous, rapid data streams . Data stream mining is a very broad concept and it involves many technical areas such as classification, detection, and clustering . In this paper, the authors mainly focus on data stream classification, because clin... |
Stevens - johnson syndrome (sjs), sjs / ten overlap, and toxic epidermal necrolysis (ten), are variants of acute, rapidly progressive mucocutaneous reactions which differ only in their body surface area (bsa) involvement . Drugs, infections, vaccines, radiological contrasts, vaginal suppositories, acrylonitrates, graft... |
In every region of the world, people s environments and lifestyles have undergone drastic changes in recent years . These changes are especially significant in industrialized countries due to the social and economic chaos they can produce . Sources of stress have become more prevalent in such societies, and people s li... |
Senior - loken syndrome (sls) is a rare renal ocular condition with autosomal recessive inheritance . The main features of this disease include nephronophthisis (nphp) leading to end - stage renal failure and early - onset retinal degeneration . Mutations in genes nphp1 - 6 and nphp10 (alias sdccag8) have been associat... |
Laparoscopic surgery is widely performed for the treatment of benign gynecologic diseases as it is associated with lower invasiveness, less pain, and shorter postoperative hospital stay than open surgery [1, 2]. In japan, where the population is rapidly aging and life expectancy is increasing, laparoscopic surgery is e... |
The specimens are slide - mounted in phenol - balsam in the manner described by wirth and marston (1968). The new species is deposited in emlio goeldi museum (mpeg) (invertebrates collection) and oswaldo cruz institute (ceratopogonidae collection) (ccer), brazil . Diagnostic characters were illustrated using a camera l... |
Is defined as a decrease in growth rate according to the reference growth charts . As a common problem in children, it is associated with some defects such as weight, height, cognitive functions, and behavior . About one - third of ftt patients suffer from developmental delay, emotional, and socioeconomic problems . Ft... |
Sepsis affects millions of people around the globe each year and is a major cause of death [1, 2]. It is defined as a systemic inflammatory response syndrome (sirs) that is caused by an infection . The standard approach to detecting the underlying infection is by culturing blood and other specimens . Blood cultures can... |
Injuries of the cuboid are uncommon and often missed.1 there were several reports about fresh fracture of cuboid,234567 but very few about the old fractures . Fracture by hermel and gershon - cohen.8 it results from forced plantar flexion and abduction, crushing the cuboid between the calcaneus and fourth and fifth met... |
The circadian clock provides the interface between an organism and its 24 hr geophysical environment . As currently accepted, the fly clock is constituted by interlocked negative transcription / translation feedback loops (ttfls). At the core of the system are the activators clock (clk) and cycle (cyc) that bind to the... |
In contrast to nociceptive pain, which arises from actual or potential tissue injury when nociceptors are activated within the peripheral somatosensory nervous system, neuropathic pain (nep) results from a lesion or disease of the peripheral or central somatosensory nervous systems.1 since nep does not respond to pharm... |
The major pathological hallmark of alzheimer's disease (ad) is the presence of senile plaques, i.e. Proteinaceous brain deposits whose main component is the amyloid peptide (a) derived by the proteolytic cleavage of the amyloid protein precursor (app). App is cleaved by three types of proteases: -, - and -secre - tases... |
Neuroendocrine tumors (nets) are a heterogeneous group of neoplasms composed of cells containing dense - core neuroendocrine secretory granules in their cytoplasm . Recent data from the seer (surveillance, epidemiology, and end results program, usa) suggest that the incidence and prevalence of nets have increased subst... |
Magnetic resonance imaging (mri) is widely used in medical research and practice due to its ability to peer inside biological organisms with superior image quality, providing high - quality soft tissue imaging while not exposing patients to potentially ionizing radiation or contrast agents . Advances in mri technology ... |
When teeth are affected by caries, they lose their ability to absorb the load from mechanical impact . Thus, when this natural complex is changed, the restorative material needs to present properties that are able to recover it in an appropriate manner . In order to achieve a satisfactory clinical performance, the comp... |
Underserved populations of latin america are going through a process of epidemiologic transition due to increases in life expectancy and changes in dietary habits and lifestyles . As a consequence, the incidence and prevalence rates of cardiovascular diseases are increasing to the point that these conditions are consid... |
Allogeneic hematopoietic stem cell transplantation (allo - hsct) is an effective treatment modality constituting the management of a variety of benign and malignant hematological disorders, especially hematological malignancies like leukemias, lymphomas and myelodysplastic syndromes . However, hematopoietic stem cell t... |
Phaeohyphomycosis is the term used to designate infections caused by demetaciaceous or pigmented filamentous fungi that contain melanin in their cell wall . During the last several decades, nephrotic syndrome (ns) is one of the most common glomerular diseases affecting children . Based on the histological findings, min... |
It has been well established that nonalcoholic fatty liver (nafld) is intimately related to various clinical and biological markers of the insulin resistance syndrome . Furthermore, there is a near - universal association between nonalcoholic steatohepatitis (nash), the severe and progressive form of nafld, and insulin... |
Over the last decades several investigations have focused on the pathogenesis of immunologically mediated kidney diseases . Besides the detection of novel aspects responsible for the onset of particular diseases, such as the phospholipase a2 (pla2) receptor and more recently thrombospondin type-1 domain - containing 7a... |
Colorectal cancer may be a devastating disease for patients if it is not discovered early in its progression . With 146,970 new cases of colorectal cancer and 49,920 deaths attributed to colorectal cancer in 2009 in the united states, indeed, some experts attribute the modest decline in colorectal cancer incidence in t... |
It has been legally used for pain management since 1980 in some countries, and has been approved by food and drug administration of iran since 2003 . Nausea, vomiting, central nervous system depression, tachycardia, cardiorespiratory arrest, and seizure are among the side effects of tramadol poisoning . However, there ... |
Choroid plexus tumors are rare and among these choroid plexus papillomas are far more common than carcinomas . They arise from the ventricles with the origin being more common from lateral ventricles in children and fourth ventricle in adults . About 2040% of all choroid plexus tumors in children are carcinomas that ar... |
Sandhoff disease is a glycosphingolipid storage disorder caused by a defect in ganglioside metabolism due to mutations in the hexb gene that disrupt the function of the n - acetyl - beta - d - glucosaminidase isoforms hex a and hex b . Ganglioside gm2 accumulates in the neural cells of affected individuals, leading to ... |
Biomineralized tissues, such as bone and dentin, manifest a remarkable stability and stiffness, which is attributed to their heterogeneous organic / inorganic composite nature . The organic matrix mainly involves fibrous collagen and to a lesser extent (glyco)proteins and citrate, whereas the inorganic part constitutes... |
A 28-year - old woman with no complaints presented with a rudimentary uterine horn pregnancy at 7-weeks gestation . Laparoscopic excision of the rudimentary uterine horn and ipsilateral salpingectomy were performed, as well as biopsy of several peritoneal endometriosis lesions . Placenta percreta may occur in rudimenta... |
Endometrial carcinoma is the second most common gynecological cancer in korea, accounting for approximately 1.8% of all the cancers diagnosed in women total abdominal hysterectomy with bilateral salpingo - oophrectomy and lymph node dissection is essential for staging and treatment of endometrial carcinoma . Adjuvant t... |
The journal of family and community medicine (jfcm), the official scientific publication of the saudi society of family and community medicine was established in 1994 as a peer - reviewed journal on general medicine . Three issues are published annually in in - print and on - line forms, and 3000 hard copies of every i... |
Breast cancer is the most common cancer in females throughout the world . In 2012, 1.7 million new cases of breast cancer were diagnosed . This represents 12% of all new cancers diagnosed and 25% of all cancer diagnoses in females . In saudi arabia, the last report on the incidence of cancer by the saudi health council... |
Inter - alpha - trypsin inhibitor heavy chain h4 (itih4) is a 120 kda serum glycoprotein secreted primarily by the liver . Itih4 is one of five human inter - alpha - trypsin inhibitor heavy chain (itih) proteins, a family involved in stabilization of the extracellular matrix (ecm). Unlike other inter - alpha - trypsin ... |
The jejunoileal atresia (jia) is a rare congenital malformation, which occurs in 1 of 5,000 newborns.1 it may occur in either the jejunum or the ileum, with single atresias being significantly more common (90%) than multiple ones (10%). Grosfeld et al classified these malformations in types i - ii - iiia - iiib - iv.2 ... |
Inflammation is the body's first immune response to protect our body from harmful stimuli, such as pathogen infection, damaged cells, and irritants [1, 2]. Symptoms include recruitment of white blood cells, pain, heat, redness, swelling, tissue damages, and dysfunctions of the organs . Acute inflammation is immediate i... |
In 2000, the discovery of coding rnas packaged into herpesvirus virions provided convincing evidence that virions of herpesviruses included more than just lipid, genomic dna, and viral proteins (bresnahan and shenk, 2000; greijer et al ., 2000). And by 2009, it was evident that non - coding rnas were also being package... |
Atopic dermatitis (ad) or atopic eczema is the common inflammatory skin disorder with a substantial socioeconomic burden and impact on quality of life.1 ad is considered as the first step of the so - called atopic march.2 the three main pillars of the management of ad, which are the basis of most guidelines include 1) ... |
The measure of the functional status in bipolar disorders is becoming a real challenge in the today research . Early emotional abnormalities and poor premorbid functioning tend to occur in bd; however, adequate psychosocial adjustment prior to the first manic episode is also common [4 - 6]. Moreover, after illness onse... |
Continuous blood supply to active muscles is necessary to maintain exercise . In patients with cardiovascular diseases, it has been suggested that synchronization between the heart beat and locomotor rhythm [cardiac - locomotor synchronization (cls)] can optimise blood flow to muscles and minimise cardiac load1, 2 . Th... |
One of the most important individual risk factors for cardiovascular disease (cvd) is hypertension.1 left ventricular hypertrophy (lvh), which is defined as an abnormal increase in left ventricular (lv) mass, is one of the organic processes resulting from hypertension.1 lvh has been widely documented to be an independe... |
Most of the scientific evidence in cardiology has traditionally focused on the left ventricle (lv). This is due to the major systemic impact when this ventricle fails and the difficulty in assessing right ventricle (rv) function correctly with the classic techniques . As a result, there are few studies focusing on the ... |
Although cervico - facial actinomycosis is well - described, primary actinomycosis of the salivary gland is rare . Actinomycosis was considered to be the commonest of all deep mycotic infections or mycetomas in the past . However, now it is well - established that it is a granulomatous lesion characterized by chronic s... |
This retrospective study included 61 children (92 eyes) with congenital cataracts who underwent surgery at the samsung medical center in seoul, korea between january 1996 and december 2006, and were followed up for at least 6 months after surgery . Eyes with traumatic cataracts and associated retinal anomalies, systemi... |
In the last decade, intravitreal injection has become the most important drug - administration route in several retinal diseases . Studies have shown that the vitreoretinal interface plays a key role in the development of macular pathologies [4, 6, 7, 11, 13, 15]. An attached posterior vitreous cortex is associated wit... |
Atrial tachycardia (at) resulting in cardiogenic shock requiring circulatory support is a rare entity . At originating from the right atrial appendage (raa) a 26-year - old woman in the 19th week of her first pregnancy presented with a chief complaint of palpitations . Electrocardiogram (ecg) showed sustained at with h... |
All animal studies were performed in accordance with guidelines of the institutional animal care and use committee at harvard medical school . The tet1-ko mouse strain (b6;129s4-tet1/j) was purchased from jackson laboratory . All male mice were mated with c57bl/6j female and the mating is timed in the way that appearan... |
Traumatic aneurysm of the superficial temporal artery (sta) was first described in the 17th century, after a blunt head trauma . Since then approximately 200 cases have been reported . The sta is one of the terminal branches of the external carotid artery, which supplies blood to the scalp [13]. Owing to its superficia... |
The porphyrias are uncommon and complex metabolic conditions caused by deficiencies in the activities of the enzymes of the heme biosynthetic pathway . Acute intermittent porphyria (aip) is inherited as an autosomal dominant disorder due to deficiency of the enzyme porphobilinogen (pbg) deaminase located in the hydroxy... |
In healthy individuals, inhaled foreign materials become entrapped in the mucus and are cleared by mucociliary transport and by coughing . However, in many chronic inflammatory airway diseases, excessive mucus is produced and is inadequately cleared, leading to mucous obstruction and infection . The inhalation of occup... |
Migraine is a common, disabling, neurological disorder with complex neurobiology that has fascinated scientists, researchers, and physicians for decades . It was considered as vascular pathogenesis and experimental work of wolff empowered this vascular theory.1 wolff s results showed that an intravenous infusion of the... |
Demographic changes in spain in recent years are similar to those in the majority of developed countries: an increasing proportion of older people and a decline in the percentage of young people . The 2011 population and housing census in spain (1), estimated that 17.3% of the spanish population is more than 64 yr old ... |
A 56-year - old woman was referred due to decreased vision in the right eye after bilateral clear lens extraction . The anterior segment examination was unremarkable and intraocular lenses were in the bag of both eyes . Fundus examination of the right eye revealed a choroidal neovascularization with retinal hemorrhage ... |
Between january 2008 and may 2012, the records of 19 consecutive patients (19 unilateral cases) who were treated using the apl suspension ligamentoplasty, were retrospectively reviewed, after obtaining the approval of our institutional review board . Indications for surgical treatment were advanced arthritis (eaton sta... |
Mesenchymal stem cells can be a safe stem cell source, and their therapeutic effects have been shown in the treatment of neurodegenerative diseases (1, 2). Previous studies demonstrated that stem and progenitor cells from adult adipose stromal tissue retain the capacity to differentiate toward mesodermal and non - meso... |
Dishabituation is a rapid recovery from habituation, often (though not necessarily) following an intense stimulus potentially in a different modality from that of the habituated stimulus . Dishabituation allows for a return of responsiveness to filtered stimuli if context or contingency changes and thus can be highly a... |
Twelve patients with type 2 diabetes (9 males and 3 females), managed by diet alone, were studied after they had provided written informed consent . The mean se age was 66.2 1.4 years, bmi 28.9 1.0 kg / m, hba1c 6.6 0.2% (48.9 2.5 mmol / mol), and duration of known diabetes 4.9 1.1 years . None had significant comorbid... |
Hpv or the human papillomavirus, is one of the most widespread sexually transmitted diseases [1, 2]. Over half of the sexually active women population hpv infection can transpire in women of all age consortium, also higher rates of hpv infectivity are generally perceived in women 20 - 24 years old . For the most part, ... |
Purtscher s retinopathy was first described in 1910 by otmar purtscher in five patients who suffered acute blindness after sustaining severe trauma.1 the patients exhibited multiple areas of retinal whitening in the posterior pole which are now recognized as cotton wool spots . Papillitis, intraretinal hemorrhage, and ... |
Acute pulmonary embolism (pe) is the most serious clinical presentation of venous thromboembolism (vte). Vte is associated with a mortality rate exceeding 15% in first 3 months after diagnosis with survivors remaining at risk for development of recurrent pe and/or chronic thromboembolic pulmonary hypertension . The cli... |
I would like to acknowledge from the outset that i have been privileged to be an invited speaker at the 70th birthday of one of my mentors, malcolm rowland, who has greatly assisted in the development of my views about science and life . There are a number of other australians, including felix bochner, garry graham, an... |
In addition to serving as a major organ for nutrient digestion and absorption, the single layer of intestinal epithelium lining the gut acts as a selective barrier to prevent the passing of toxins, allergens, and pathogens from the luminal content into the circulation system and other tissues . Dysfunction of the intes... |
Radiation - induced gastrointestinal disorder is the most common complication of toxicity due to the treatment for malignancies in the abdomen and pelvis, which often reduces the quality of life (qol) for patients and occasionally limits the therapeutic dose that can be used for treating abdominal and pelvic tumors wit... |
Sarcomatoid renal cell carcinoma (rcc) is a distinct histological variant of rcc observed in around 0.7% to 13.2% of renal parenchymal carcinomas [1 - 4]. This form of the disease is associated with rapid progression and a very poor prognosis and there is currently no uniform consensus regarding the treatment of patien... |
Protein - bound lys with its free -amino group is considered the amino acid that is most susceptible to react with other compounds present in ingredients, foods, and feeds during thermal processing . One example is the reaction between amino groups and reducing sugars (maillard reaction), resulting in the formation of ... |
The upper limit for regulatory complexity in the genome is not known, yet such a limit must exist . Taking alternative splicing as an example, although one might easily imagine a gene that produces 20 splicing isoforms, a gene with 200,000 isoforms appears highly unrealistic, due to the overwhelming amount of regulator... |
Data from the childhood obesity surveillance initiative by the world health organization's (who) regional office for europe indicate that the number of 69 year - old children who are overweight (including those who are obese) climbed from 1 in 4 to 1 in 3 between 2008 and 2010 (humphreys & fiankan - bokonga 2013; wijnh... |
World health organization s projections for 2030 suggest about 51.5 million deaths (76% of the global mortality), demanding a course of action based on improvement in lifestyle and health behaviors (1). Progress in the methods of the diagnosis and treatment of cardiovascular disorders has conferred increased survival .... |
Air pollution is an international issue because of the transnational movement of pollutants across continents and oceans (3). Local sources usually only comprise part of the concentrations of particulate air pollutants in cities (4). However, an overlooked aspect of air pollution is indoor exposures . It has been estim... |
Anti - n - methyl - d - aspartate receptor (nmdar) encephalitis is a synaptic autoimmune disorder in which immunoglobulin (ig)g autoantibodies recognize the glun1 (also termed nr1 or nr1a) subunit of nmdars.1 according to available studies,14 in most patients, development and progression of the disease occurs in well -... |
Bipolar disorder (bd) is a lifelong condition that highly impairs functioning and quality of life and increases the risk of a range of psychiatric and somatic comorbidities . For a long time, bd was rarely diagnosed in pediatric populations . However, studies have shown that approximately 30%60% of individuals diagnose... |
In a field where the quality and beauty of sound is the product of the activity itself, the workers of the music sector suffer from the unwanted part of the sound represented by noise . In particular, the professional orchestral musicians are widely recognized to be exposed, other than occasionally, to noise levels exc... |
Hand protaper instruments represent a revolutionary breakthrough when it comes to mechanical treatment of root canals . It has some advantages compared with those of steel or nickel - titanium due to its convex triangular cross - sectional shape, its tip designed for guiding and the fact that its helical angle and slop... |
In phylogenetic trees of coelacanths, lungfishes and tetrapods, these lineages are connected by short branches and coelacanth and lungfish have long branches in constructed phylogenetic trees (e.g., amemiya et al . ; braasch et al . 2016; takezaki and nishihara 2016). In such cases the relationships of the taxa become ... |
A 64-year - old man was admitted due to fever, myalgia, dysarthria, dizziness, and headache that had first appeared several days previously . He had worked at a sewage disposal plant in the northern rural area of seoul . He had suffered from mild conductive hearing impairment of undetermined cause in the left ear for s... |
The s. aureus strains studied included 44 nasal isolates from healthy pig farmers and 21 from healthy nonfarmer controls (i.e., bank or insurance workers). These participants all had been part of the population included in a previously published epidemiologic study in which the resistance rates in commensal bacteria fr... |
Functional motor symptoms (fms), which include abnormal movements and weakness, are part of the wide spectrum of functional neurological symptoms, one of the commonest diagnoses made in neurological practice.1 patients affected by fms have levels of disability, distress and healthcare usage that equals, and in some cas... |
Transmissible skin disorders (tsd) represent a substantial part of dermatology . It is known that some tsd are more frequent in childhood and are related to several socio - demographic and environmental factors . Our aim was to determine the prevalence and the nature of common tsd among male primary school children in ... |
Prepare a 4-well labtek ii chambered coverglass by adding 0.5ml of fibronectin (10g / ml) to each well that will be used . Incubate for 10 - 15 minutes at room temperature . Prepare sirna / lipofectamine rnaimax (invitrogen) complexes for reverse transfection according to manufacturer s instructions . Use the recommend... |
Percutaneous vertebroplasty is widely used for the treatment of painful osteoporotic compression fracture (ocf) of the spine . Many previous studies, including guidance documents from the us food and drug administration19), have recommended delayed vertebroplasty (dvp) only after a course of failed medical therapy, on ... |
Cervical perforations that occur relatively close to the crestal bone and epithelial attachment may have a critical prognosis despite favourable visualization . This is attributed to bacterial contamination from the oral environment along the gingival sulcus, which delayes the repair process . Light - cured glass ionom... |
Central pontine myelinolysis (cpm) is an acute, non - inflammatory demyelinating disease of the pons of the central nervous system (cns) (1). The etiology and the pathogenesis of cpm remain unclear, but too - rapid correction of hyponatremia is often associated with cpm, which is the result of the selective loss of mye... |
One of the most daunting tasks for an ophthalmic surgeon is the management of complicated cataracts . Cataract in uveitis may develop as a result of the intraocular inflammation per se, from chronic corticosteroid usage or more often from both . The incidence of cataract in uveitis varies from 57% in pars planitis to 7... |
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (cadasil) is a hereditary disease of the cerebral small blood vessels caused by mutations in the notch 3 gene.1 the main clinical manifestations are recurrent ischemic strokes, migraine, and progressive cognitive impairment.1 epi... |
Pompe disease is a lysosomal storage disorder caused by a deficiency in the enzyme acid -glucosidase (gaa). The consequence of gaa deficiency is muscle inflammation, disruption of muscle tissue, and impaired function of heart and skeletal muscle . Although the advent of enzyme replacement therapy (ert) for pompe diseas... |
The cell line nih 3t3 was cultured in rpmi 1640 media, and cytogenetically worked up according to standard procedures . Fish was done as previously reported using human mcb probe sets (liehr et al . Murine mcb probe sets for chromosomes 1, 3, 6, 18, 19, and x were established earlier (trifonov et al . The mcb probe set... |
Achalasia cardia may cause chronic passive aspiration and varying degree of respiratory tract inflammation / pathology . Associated dehydration, malnutrition, and poor bronchial ciliary movement may lead to formation of tenacious mucous secretions that can block endotracheal tube (ett) perioperatively . Blockage of the... |
Clinical consequences of the atherosclerotic process, in the form of ischaemic heart disease, disorders of cerebral circulation, or circulatory disorders of peripheral arteries occur in the adult population; however atherosclerotic changes have their beginning in childhood . The severity of atherosclerosis correlates w... |
Current views of eukaryotic cell evolution disagree on whether the endosymbiotic acquisition of mitochondria occurred early (lane et al . A recent article in nature concludes that mitochondrial endosymbiosis was a late event (pittis and gabaldn 2016). However, this conclusion is based upon phylogenetic inferences that ... |
Cardiovascular - related diseases are the most serious threat to human health that authorities will have to manage worldwide . All of these pathological outcomes, like stroke, thrombosis, or infarction, are pathological events resulting from the long - lasting and silent process, known as atherosclerosis . Atherosclero... |
The word menopause was coined specifically for human females, where the end of fertility is traditionally indicated by the permanent stopping of monthly menstruations . However, menopause also exists in some other animals, many of which do not have monthly menstruation . In this case, the term means a natural end to fe... |
Speech - evoked, auditory event - related potentials or simply the speech evoked potentials (seps) described by many contemporary researchers can provide informative value regarding the neural mechanisms that underlie speech processing by the human auditory system.1) although click stimuli are useful in that they effec... |
Causes of mental disability or intellectual disability and sensory and physical - motor problems among children are very diverse . Birth and neonatal morbidities, preterm birth, and environmental factors are some other causes . In many cases, genetic background, geographical location, nutritional status, environmental ... |
Mucus overexpression and hypersecretion in the human respiratory track are a critical characteristic of a number of pulmonary diseases including rhinitis, sinusitis, asthma, copd, and cystic fibrosis . A family of highly glycosylated proteins, named mucins, has been identified as important constituents of mucus . Howev... |
The peripheral sensory systems including the visual, proprioceptive, auditory, and vestibular systems provide feedback from the environment, facilitating interaction and engagement with the external world . Each sensory system may become impaired with age, contributing to increased isolation from the outside world . Ag... |
Kars are made up of various combinations of five subunits: gluk5, gluk6, gluk7, ka1, and ka2 [1, 2] which are abundantly expressed in the neocortex . These subunits make up tetramers of either homomeric or heteromeric assemblies, with gluk57 being able to form functional homomeric receptors [1, 4]. Ka1 and ka2 cannot f... |
Polymyalgia rheumatica (pmr) is a relatively frequent disease with a prevalence between 13/100,000 and 133/100,000, with a predominance of people aged> 70 years.1,2 it has been proposed that environmental factors and infectious agents are plausible in the etiology and pathogenesis of pmr.3 in this context, six case rep... |
Autoimmune diseases are generally characterized by the body s immune responses being directed against its own tissues, causing prolonged inflammation and subsequent tissue destruction. (1) a hallmark of autoimmune diseases is the production of autoantibodies such as antinuclear, anti - sm and anti - dsdna in systemic l... |
Paget's disease of bone is a form of osteodystrophy characterized by disorganized formation and remodeling of bone, unrelated to functional requirements . It is the second most common bone disease after osteoporosis (kanis, j.a . ). The disease is characterized by focal regions of highly exaggerated bone remodeling, wi... |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.