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Diabetic retinopathy (dr) is a progressive neurodegenerative disease, with early - stage symptoms such as dysfunction of muller cells, which leads to ganglion cell death . Its pathogenesis is probably associated with oxidative stress, which promotes the production of reactive oxygen and nitrogen species (ros / rns) and... |
Visfatin, as an adipocytokine, is encoded by a gene, officially now known as nicotinamide phosphoribosyltransferase (nampt), but formerly known as pre - b - cell colony - enhancing factor (pbef1) gene . Visfatin is a 52 kda large protein and its gene is located on chromosome 7q22.2.2 . It is found that visfatin is expr... |
Hydatid disease is a worldwide zoonosis caused by infection with a small tapeworm parasite called echinococcus granulosus . Sheep and cattle are intermediate hosts for the pastoral form, and humans are an accidental intermediate host (12). Patients with hydatidosis usually present with hepatic (liver) (75%), pulmonary ... |
This was a preplanned interim analysis (at 84 weeks) of an open - ended, controlled extension (expected to last at least 2.5 years) of a previously reported 26-week, phase 3, multicenter, open - label, randomized, two - arm, parallel, comparator - controlled trial in patients with type 2 diabetes failing to maintain su... |
Data are sparse on demands and satisfaction of these patients with service delivery and system performance in austria . The analysis and comparison of the patient questionnaires is aimed at collecting data on patients' needs and their priorities in chronic care within the austrian health system . The patient questionna... |
Many biological systems and pathways, not only from bacteria, archaea, and fungi, but also from plants (field and osbourn 2008) and animals (garcia - fernandez 2005) are encoded by genes that are physically clustered together on the chromosome in operons or gene clusters (fischbach and voigt 2010). The architectures of... |
Type 2 diabetes (t2d) is the most common form of diabetes, afflicting more than 80% of all people with the disease . T2d is a metabolic disorder characterized by chronic hyperglycemia due to insulin resistance and/or impaired insulin secretion . Despite the increasing incidence and prevalence of t2d, little is known ab... |
Oculomotor nerve palsy, in contrast to paralysis of the fourth or sixth cranial nerves that may affect the function of only one extraocular muscle, may affect the function of four of the six extraocular muscles . In complete third - nerve palsy the eye is fixed in a position of abduction, depression, and intorsion, bec... |
Deep vein thrombosis (dvt) is formation of blood clot (thrombus) within the deep veins of any parts of the body . Major complications of venous thrombosis are a disabling post - thrombotic syndrome and acute death from a pulmonary embolism (pe) that occur in 20% and 1 - 2% of patients, respectively . The development of... |
The endothelium has emerged as a key regulator of vascular homeostasis, acting as an active signal transducer for metabolic, hemodynamic, and inflammatory factors that modify the function and morphology of the vessel wall . Alterations in endothelial - cell function can precede the development of atherosclerotic change... |
Obturation materials are used in root canal therapy (rct) to entomb the residual microorganisms or their toxins, fill the inaccessible areas, and seal the canal in order to prevent coronal leakage which is a major cause of rct failure. [18] the obturation mainly depends on the sealers to prevent ingress of microorganis... |
High tibial osteotomy has been recognized as a standard procedure for the treatment of medial compartment osteoarthritis of the knee with varus deformity . Although it can be performed with either an open or closed wedge technique, open wedge high tibial osteotomy (owhto) is being employed with increasing frequency bec... |
Along with the advances in modern therapy however, the expected outcome has improved significantly . Patzakis et al reported their seminal randomized, controlled trial of cephalothin, a first generation cephalosporin for the management of open fractures . In the past, cultures were routinely done before and after debri... |
Cerebrospinal fluid (csf) otorrhea, which is occurred by secondary causes, such as a congenital development disorder of inner ear, surgery, trauma or cholesteatoma, is generated from a fistula that is formed when the barriers between the mastoid part of the temporal bone and the bone matrix of skull are breakdown.1) th... |
Elevated levels of inflammatory cytokines may lead to phosphorylation of serine residues on the insulin receptor substrate, which prevents its interaction with insulin receptors, inhibiting insulin action . Mammalian stomach produces leptin and ghrelin, two hormones involved in energy homeostasis and whose interactions... |
The clinical forums component has small group sessions with faculty, senior students, and peers regarding doctor - patient interactions and communication, case - based presentations and discussions, and application of medical ethics and professionalism principles . In the diagnostic reasoning component, students comple... |
Cytomegalovirus (cmv) infection of the gastrointestinal tract is one of the more uncommon opportunistic infections in aids . The incidence of cmv infection and complications in people already afflicted with cmv has dropped precipitously after the advent of highly active antiretroviral therapy (haart) [2, 3, 4]. Patient... |
Intubation of the terminal ileum was not routinely attempted during colonoscopy due to time constraints and sometimes technical difficulties unless there is a suspicion of inflammatory bowel disease . Since the introduction of quality indicators for colonoscopy completion has included the need to document at least 2 la... |
Diffuse axonal injury (dai), also known as axonal damage or dysfunction, is regarded as the most common and important pathology of traumatic brain injury (tbi). Previous studies have ascribed typical axonal injury to shear stresses induced by rotational head acceleration / deceleration . However, recent studies have sh... |
Painful form of the diabetic peripheral neuropathy (dpn) is one of the most commonly encountered neuropathic pain syndromes in clinical practice, that is very uncomfortable for patients and despite recent improvements in its treatment, the pain is often inadequately controlled . Several medications, mostly antidepressa... |
Idiopathic nephrotic syndrome (ins) includes minimal change disease (mcd), focal segmental glomerulosclerosis (fsgs), and diffuse mesangial proliferation (dmp). Patients with mcd usually have excellent prognosis, but patients with fsgs and dmp often have hypertension, hematuria, and progress to renal failure [14]. Ster... |
Copd is one of the major causes of death ranking fourth worldwide, and it is predicted to become the third leading cause by 2030 (http://www.who.int/healthinfo/),1 making this disease one of the major health challenges.2 the best way to reduce the prevalence of copd is to control for risk factors; although it is genera... |
The type 2 diabetes mellitus (dm2) is a widespread noncommunicable disease (over 380 million patients worldwide). It is characterized by a pronounced insulin resistance, moderate hyperglycemia, hyperinsulinemia, dysfunctions of pancreatic -cells, and impaired lipid metabolism . Functional and metabolic abnormalities pr... |
Eclampsia is a disturbance of the central nervous system in obstetric patient(s) characterised by seizure activity or coma with or without a prior history of hypertension in pregnancy, proteinuria, and/or oedema (preeclampsia) [13]. Eclampsia may occur during pregnancy, child birth, or as long as 3 weeks after birth . ... |
If a sensitive infrared photodarlington is placed in series with the switch input of the computer interfacing equipment it will act in a manner similar to a mechanical switch . When the sensor is in infrared shadow, the circuit is open; if infrared radiation falls on the photodarlington the circuit will close . We have... |
Fungal infections caused by candida species are increasing, particularly in immunocompromized individuals . C. albicans is the most common opportunistic fungal pathogen involved in health problems encountered in humans . However, infections by other candida species are gaining ground worldwide, particularly in nosocomi... |
. The cyst may either be congenital (developmental) or acquired . To a large extent, the differential diagnosis depends on its location in the mediastinum (anterior, middle or posterior compartments). The cysts of non - infective etiology may be complicated by secondary infection and certain primary infectious conditio... |
Chronic kidney disease (ckd), defined by the presence of kidney damage and/or reduced function for a period greater than 3 months, is an increasingly relevant public health problem all over the world . According to a very recent systematic analysis, in 2010 the global prevalence of ckd in adults was 10.4% in men and 11... |
(irvingiaceae) has become known as african mango and is unrelated botanically to the common, or indian, mango [mangifera indica (anacardiaceae)]. The fruits of african mango are edible, and their use in traditional medicine has been documented for the treatment of gastrointestinal or hepatic disorders, diarrhea, infect... |
The specialized registered nurses working in the technologic homecare team of our organization are highly qualified in technical nursing . One component of their job is the intravenous administration of medication to patients in their own home by using an infusion pump . In a hospital setting you can ask a colleague nu... |
At weaning, mule deer fawns were orally infected with approximately 1 g of nonspecific, pooled, infectious brain material placed at the base of the tongue; based on previous analyses, the inoculum pool contained approximately 3 g prp per g of brain tissue and showed prion conversion in vitro and infectivity in vivo . A... |
Paragangliomas (pgls) are rare and highly vascular tumors of neural crest origin that comprise only 0.6% of all head and neck tumors.1 formerly known as glomus tumors, or chemodectomas, pgls develop from the extraadrenal chromaffin and chief cells of autonomic paraganglia in various locations throughout the body, usual... |
The disease arises when beta cells produce insufficient insulin to meet the increased hormone demand, caused by insulin resistance or growth of tissues such as liver, muscle, and adipose tissues . Although genome - wide association studies revealed a genetic contribution in the etiology of the disease, the environmenta... |
Serotonin syndrome refers to a disorder which results from excess serotonergic stimulation at central and peripheral serotonin receptors, usually caused by drugs or drug interactions . It was first defined in 1955, but the precipitating drugs, signs, and symptoms became more common only after 1990s . Despite its high p... |
Root coverage procedures are frequently indicated to resolve a variety of patient - centered concerns including, but not limited to, root sensitivity, increased potential for root caries, difficulty in plaque control and esthetics . The coronally advanced flap (caf) to cover denuded root surfaces has been considered to... |
Stroke results in serious complex functional problems in many areas, especially cognitive and physical impairments that significantly limit their activities of daily living (adls)2 . Eventually, stroke survivors after returning to living in the community after discharge would need to attend alternative rehabilitation p... |
As mentioned earlier, eighteenth - century medical practitioners, for obvious reasons, did not operate in a modern world of carefully controlled clinical trials . Yet their attempts to cure patients were also not as random as they might appear to the modern eye . Rather, eighteenth - century medical practitioners typic... |
Two subspecies of this parasite, t. b. gambiense and t. b. rhodesiense, are responsible for the infection called human african trypanosomiasis (hataaabbreviations: 6-pgdh, 6-phosphogluconate dehydrogenase; hat, human african trypanosomiasis; phlm, pooled human liver microsomal assay . ), which is one of the most lethal... |
An expanded version of the research design and methods has been described in the online appendix that is available at http://diabetes.diabetesjournals.org/cgi/content/full/db09-0681/dc1 . In this supplement, we have explained our animal model of hypoinsulinemia, perfusion of isolated hearts, isolation of cardiomyocytes... |
High blood pressure is commonly found in patients with chronic kidney disease and renovascular hypertension is a common form of secondary hypertension and frequently resistant to pharmacologic treatment . In the two - kidney, one clip (2k1c) goldblatt model, renovascular hypertension is induced by unilateral renal arte... |
Thanks to the development of micro - arrays first and next generation sequencing later, gene expression studies have been one of the major determinants for understanding the pathophysiological changes in duchenne patients cell lines and muscles as well as in animal models [5663]. The genes identified in several indepen... |
Malignant distal biliary obstruction (mdbo) is a frequent complication of pancreaticobiliary and metastatic malignancy . Endoscopic retrograde cholangiopancreatography (ercp) is the current gold standard for decompressing the biliary tree in this population 1 2 3 4 . However, ercp can be unsuccessful in 5% to 10% of pa... |
The link of lifestyles, such as dietary patterns and physical activity, to the risk of developing cancer and other diseases has received support from a plethora of epidemiological and biochemical studies . In line with this, a report from the world health organization (who) states that cancer causes 7.1 million deaths ... |
For many years, chronic neurodegenerative disorders of the central nervous system (cns) were thought of in terms of primary neuronal dysfunction and loss with secondary glial and inflammatory responses . These responses were defined by an astrogliosis and the presence of a few activated microglia, but of late this theo... |
Invasive fungal infections (ifi) are increasingly encountered in clinical settings, in particular in immunocompromised patients with haematological malignancies, and cause significant morbidity and mortality . Aspergillus species, mainly belonging to the aspergillus fumigatus complex, are the most frequent causal agent... |
Lateral gene transfer (lgt), the transmission of genetic material from one species to another by means other than direct inheritance from parents to the offspring is a prevalent phenomenon in prokaryotes . Lgt contribution to the composition of today bacterial genomes is so high that it challenges the idea that genome ... |
Tonsillectomy is the most common surgical procedure performed in the ear, nose, and throat practice . It is most frequently performed via cold dissection both in the pediatric and adult age group worldwide . Hot dissection methods include bipolar and/or monopolar electrocautery, radiofrequency, harmonic scalpel, coblat... |
Speaking at a meeting of the society of general physiologists in 1958, george palade referred to what he called the heidenhain hypothesis . Rudolph heidenhain, a german physiologist, proposed in 1875 that large vesicles in the apical cytoplasm of pancreatic exocrine cells, which he called zymogen granules, were the int... |
Miniemulsion polymerization is an advantageous process for the encapsulation of insoluble components into a polymer matrix . This has been of ongoing interest in academics and industry in the last few years . Many different applications for hybrid nanoparticles with encapsulated components have been developed, for exam... |
Hereditary inclusion body myopathy (hibm) is a neuromuscular disorder that is characterized by early adulthood onset, ethnic predisposition, distal and proximal weakness, and quadriceps sparing . The first patient affected with hibm was described in 1984 among iranian jews . In the iranian jewish population, autosomal ... |
Laparoscopic nissen fundoplication is a common procedure performed in many patients experiencing symptomatic gastric esophageal reflux . Common complications associated with the procedure include pain, bleeding, infection, failure of the procedure, and gas - bloat syndrome . As part of the technique, in addition, this ... |
Two - photon laser scanning microscopy represents one of the main techniques for high - resolution in vivo imaging of central nervous system (cns) [14]. By this approach have been revealed new details of neuroglial dynamic interactions in either physiological and pathological conditions [59]. This has generated a yield... |
O'brien and colleagues recently published results from the national sepsis practice survey, in which participating physicians were given simulated clinical vignettes of patients in septic shock and asked to predict their morbidity and mortality and to make recommendations about withholding life support . Although the v... |
Adult horse and deer flies, or tabanids (diptera: tabanidae), blood feed on wild / domestic animals and humans . They are serious pests wherever they occur, resulting in economic losses in the dairy and beef industries due to reduced milk and meat production . Tabanids pose a threat to animal health and hygiene because... |
An advanced integrated circuit (ic) typically has eight or more wiring levels, each of which consists of metal via and line structures . The metal lines distribute signals within each interconnect level, whereas metal vias transmit signals between the adjacent wiring levels . In state - of - the - art ics, copper is us... |
In osteoporosis, there is an imbalance between bone resorption and bone formation leading to bone loss and structural decay of the skeleton.currently available therapeutics affect bone resorption and bone formation in the same direction and either decrease (inhibitors of bone resorption) or increase (pth peptides) bone... |
Our knowledge about the pathogenesis of alzheimer s dementia (ad) has expanded dramatically over the last decade . Unfortunately, these findings have not been successfully translated into new therapies for ad . These attempts by the pharmaceutical industry to find new treatments have not been successful during the last... |
Metals are subjected to biodegradation in the oral environment by dissolution in saliva, chemical / physical destruction, wear and erosion caused by food, chewing and bacterial activity, humidity, variation of temperature and ph1,7,14 . The metallic ions released into the oral cavity will be in contact with adjacent ce... |
Hip fractures are commonly seen fractures in the elderly and are associated with moderate to severe pain . Peripheral nerve blockade used for anaesthesia is rarely effective beyond the first post - operative night . Approximately 40% of patients presenting with hip fracture have at least moderate renal dysfunction; hen... |
Despite comprehensive studies on the anatomy and embryology of the ophthalmic artery (oa), variability of the oa had remained a teaching challenge in the past . Today, imaging has paved the way for improved identification of oa variants, embryological explanations, and clinical interpretations . Upon studying the liter... |
A 46-year - old woman suffering from severe back pain caused by a ruptured herniated neucleosus pulposus (hnp) at the level of the l1 - 2 intervertebral disc underwent a transforaminal epidural block . We used 5 ml of 0.5% ropivacaine, 2 mg of dexamethasone, 1,500 iu of hyaluronidase (h - lase, gunil, seoul, korea, pow... |
Neurofibromatosis type i (nf - i) also known as von recklinghausen's disease, is an autosomal dominant disorder that involves abnormal growth of neuroectodermal tumors in the peripheral nervous system . Nf - i is due to mutations in the neurofibromin - encoding gene that is located on chromosome 17q11.2 with characteri... |
Primary intramedullary spinal glioblastoma multiforme (sgbm) is a rare disease entity and accounts for only 1 to 5% of all gbms and only 1.5% of all spinal cord tumors . It tends to have a predilection in the cervical region in primary cases and more often occurs in younger patients (<30 years of age). Despite the best... |
The obsessions are recurrent thoughts, impulses, or images, which are intrusive and ego dystonic; they are related to basic fears or urges that are distressing to the individual, such as contamination, aggression, sex, religion / scrupulosity, order / symmetry, hoarding, or pathological doubt . The compulsions are repe... |
The indian gerbil, tatera indica (hardwicke) is believed to be the main reservoir host of zoonotic cutaneous leishmaniasis (zcl) in khuzestan province, in border of iran and iraq, southwest of iran . Khuzestan province is an important focus of zcl in iran and the reports shows that the occurrence of the disease has inc... |
Autoimmunity is characterized by the breakdown of self - tolerance leading to a state of abnormal humoral and cell - mediated responses agaissnst self - components . Psoriasis is an immune - inflammatory skin disease affecting 2 - 3% of the general population which can be associated with psoriatic arthritis (psa), enth... |
Listeria monocytogenes is a gram positive, facultative intracellular, foodborne pathogen responsible for cases and outbreaks of listeriosis . Listeria was first described in 1926 by murray et al . Who discovered it while investigating an epidemic infection among laboratory rabbits and guinea pigs . At that time, it was... |
Cachexia is a wasting condition, directly associated with 2240% of all cancer deaths.1, 2 it has been defined as a multifactor syndrome, characterized by ongoing loss of skeletal muscle mass (with or without loss of fat mass) that cannot be fully reversed by conventional nutritional support and leads to progressive fun... |
Diabetes mellitus (dm) is one of the threatening factors which increases the risk of cardiovascular accidents during cardiovascular diseases . Metabolic changes developing during diabetes mellitus aggravate disorders of functional state of cardiomyocytes in heart failure (hf) [24]. It is caused to a great extent by cha... |
The highest rate of spread of this disease in iran is in the southern and northern regions . A regular blood transfusion in thalassemia patients is necessary to improve a patient s overall survival (1). On the other hand, this has led to improving the quality of life and life expectancy in these patients . However, the... |
Hepatitis b virus (hbv) is a dna virus with approximately 3200 base pairs . Approximately 350400 million people are chronically infected with hbv and more than 3 billion people have been exposed to hbv worldwide [1, 2]. Hbv induces a variety of liver diseases, ranging from acute or fulminant hepatitis to liver cirrhosi... |
Developmental dyslexia (dd) is characterized by deficiencies in reading and writing with phonological difficulties persisting throughout life . Previous studies have demonstrated genetic components for dd with at least nine loci (dyx1 - 9) identified, and perturbed gene expression or human loss of function phenotypes h... |
Primary liver cancer is the third most common malignant tumor and the second leading cause of death from malignant disease in men in korea . A variety of single agents has been tested in phase ii trials without documented success . And therefore, studies of new agents, especially drugs with novel mechanisms of action, ... |
The liver and lungs are the most frequent locations of e. granulosus infection, whereas 0.52.0% of all cases occur in the musculoskeletal system, of which 50% of cases are spinal hydatid cyst . The appearance of a dumbbell - shaped mass in the thoracic spine is highly suggestive of neurofibroma . Hydatid cysts of the b... |
The discovery of the role of human epidermal growth factor receptor 2 (her-2) in breast cancer research was the result of the observation of amplified her-2 in breast cancer cell line models, prompting analysis of clinical breast cancer specimens . This translational breast cancer research effort was driven by its prev... |
In western developed countries the atherosclerosis - related diseases, such as cardiovascular disease (cvd), remains so far the major cause of morbidity and premature death . For this reason, atherosclerotic cardiovascular disease represents a major public health concern, and many efforts are addressed to better unders... |
The sick child, painted by gabriel metsu in 1660, inspired the subject of this article.1 the ailing child gazes listlessly out of the painting, her fragile, pale form contrasting against the solid, bright presence of her nurse or mother.2 although the painting is dutch, it sparks a host of questions relevant to childre... |
After dfo functionalization, we radiolabelled murine or human apo - tf with zr (see supplementary information for synthetic details, see also supplementary figs . 2 and 3, and supplementary table 1). Dfo - conjugates were functionalized with an average of 2 chelates per molecule of tf and in all radiolabelling experime... |
Anti- n - methyl - d - aspartate (nmda)-receptor encephalitis is a recently described syndrome of psychiatric symptoms and neurologic sequelae associated with ovarian teratomas . Due to the rarity of anti - nmda - receptor encephalitis, diagnosis may be delayed while more common conditions, such as primary psychiatric ... |
Collaborative nursing research across academic and practice settings is essential for the advancement of science that generates new discoveries and determines effective approaches for research translation and implementation . Multiple national and international studies highlight benefits of academic - practice research... |
It is a cause of primary atypical pneumonia, but many infections are asymptomatic or cause only mild symptoms, such as pharyngitis and bronchitis (1). Thus clinical findings are seldom diagnostic for m. pneumoniae infection . M. pneumoniae infections are endemic in large urban areas and epidemic increases are observed ... |
While the involvement of extraocular muscles (eoms) in patients with graves' disease may seem infrequent on clinical examination, orbital magnetic resonance imaging (mri) studies suggest that the majority of such patients have eom enlargement . Along with the orbital fibroblast, the eom is likely to be a primary target... |
In july 1925, the psychiatrist albert moll appeared before the district court in berlin - schneberg charged with having defamed the apport medium maria vollhardt the plaintiff, hermann rudloff the medium s husband claimed that the defendant s use of terms such as trick, manipulation and farce in his 1924 book, der spir... |
Ham yen orange tree has been domesticated since 1890s by muong minority people in ham yen district of mountainous province tuyen quang of northeast vietnam . This species produces the most nutritious and economically valuable fruit with current growing area of 4,900 hectares and yield of about 43,000 tons by 2015 and b... |
Cardiac myxoma is sporadic and is commonly found in the left atrial cavity in middle - aged women . Myxoma needs an early diagnosis and urgent operation because of sudden death, embolization and systemic symptoms . We present a young female patient with multicentric biatrial myxoma who had no familial history . Surgica... |
Increasing attention by both the scientific community and lay public is being directed at the use of probiotic organisms for various indications, some of which are supported by clinical research . Probiotics have been suggested as having benefit in decreasing vaginal infections and in regulating the gut flora to decrea... |
Dysomia and hyposmia are uncommon symptoms of hypothyroidism . These symptoms are generally ignored by both the physicians and the patients . We present here one such case where the patient presented with such symptoms but was diagnosed timely and treated . A 35-year - old male presented with intolerance to cold, dryne... |
Osteoporosis has been recognized as a debilitating disease since the mid 1990s.1 the most common type is postmenopausal osteoporosis, but osteoporosis secondary to disease or drug use is not infrequent . The major consequences of osteoporosis are low - trauma fractures, which seriously impact patients quality of life, ... |
The kidney removes numerous waste solutes from the blood plasma . When kidney function is lost, these solutes accumulate in the body and cause uremic illness culminating in death unless renal function is partially replaced by dialysis . At present we know remarkably little about which retained solutes are toxic, and th... |
A 32-year - old female patient underwent vitrectomy, air - fluid exchange, and silicone oil injection in the left eye for the treatment of proliferative diabetic retinopathy in october 2002 . Six months after the ambulatory follow - up, vitrectomy, air - fluid exchange, and silicone oil injection were performed on her ... |
Fifty - three adolescents (meansd age, 17.2 1.7 years) meeting the criteria for dbd, that is either cd or odd in accordance with the dsm - iv - tr (american psychiatric association 2000) were recruited from judicial and forensic / orthopsychiatric institutions for youth in the netherlands, and compared to 99 adolescent... |
Anterior cervical diskectomy and fusion (acdf) is commonly used as a surgical treatment for symptomatic cervical disk herniation and cervical spondylosis that is refractory to conservative management.1 2 following acdf, imaging modalities such as standard radiography and computed tomography (ct) are used to assess the ... |
Alveolar bone height is the distance between the cement - enamel junction (cej) and the alveolar bone crest (abc), along a line parallel to the long axis of the tooth . This distance indicates whether there is alveolar bone loss (abl) and bone alterations due to periodontal disease . Although studies showed considerabl... |
Statins are competitive inhibitors of 3-hydroxy-3-methylglutaryl - coenzyme a (hmg - coa) reductase; this class of drug is commonly used to reduce serum cholesterol levels, and the effectiveness of statins in preventing heart attack and stroke was documented . Preclinical studies have reported that statins potentiate a... |
Glaucoma is the second leading cause of blindness worldwide, and the sub - saharan african population shares a disproportionate amount of this disease burden.1 intraocular pressure (iop) lowering is the only proven method to prevent the development2 and/or slow the progression of glaucomatous optic neuropathy.3 the use... |
Chemo- and enantioselectivity in hydrogenation of,-unsaturated carbonyls on transition metals is a topic of ongoing research in the field of heterogeneous catalysis . Particularly important is the possibility to tune surface chemistry of multiunsaturated hydrocarbons, such as,-unsaturated ketones and aldehydes, and the... |
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