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This prospective study was performed from september 2012 to july 2013 . Prior approval from the institutional review board of the institute this study was conducted in accordance with the tenets of the declaration of helsinki . For inclusion in the study group, participants were required to have a history of diabetes m...
Dacryocystitis is an infection of lacremical sac due to obstruction of nasolacrimal duct which has primary or secondary causes . Trauma, infection, inflammation, neoplasia, and mechanical obstruction are secondary one (1). Clinical features of this disease is pain, swelling, redness over the lacrimal sac at medial cant...
Residual masses after cisplatin - based chemotherapy in germ cell tumor (gct) contain complete fibrosis / necrosis in 40 to 50% of the patients, mature or immature teratomatous elements in 35 to 40%, and malignant tumor in 10 to 15% of patients . In the present study, we report one patient with late relapse and other w...
Mofs used here were prepared according to previously reported methods . In the case of 20% dpa incorporation in mof, after 468 mg of dpa was dissolved in 1 ml of 1,1,1,3,3,3-hexafluoro-2-propanol, mof, 2.34 g, was added and then the solvent was extracted by rotary vacuum . The resulting solid dpa - mof compound was fur...
However, combination therapy has its own disadvantages and irrational use can worsen the already alarming scenario of antibiotic resistance . Antibiotics are most commonly overused in subgroup of less severely ill patients . Identifying the subgroup of patients who are likely to benefit from combination therapy and res...
Rip320 and trif mutant (strain - c57bl/6j - ticam1) 19 mice have been described previously . Embryos and yolk sacs were harvested from timed pregnancies at the indicated day post - coitus . Fatal hepatitis was induced by intraperitoneal injection with 12.5 g of anti - mouse fas antibody (clone jo2, bd biosciences). Tis...
Probiotics for humans use are subject to minimal restrictions and come in many different forms . Probiotics in animal feed have been used for the prevention of gastrointestinal infections, with a wide use in poultry and aquaculture productions [16]. Diarrhea is one of the major side effects of chemotherapy in cancer tr...
We conducted a 35-week randomized, double - blind, placebo - controlled, crossover study, with two 16-week treatment periods separated by a 3-week washout period (supplementary fig . All study visits were conducted in the beth israel deaconess medical center general clinical research center in boston, massachusetts . A...
Tooth extraction will be followed by unavoidable changes in supporting structures and these changes alter the three - dimensional situation of the alveolar process, which can impede restorative fixed treatments . Resorption processes are accelerated at the presence of periodontal diseases, and this could make prosthesi...
Prostate cancer (pc) remains the most common cancer in men in the western world . The gold standard tools currently applied for the diagnosis of pc include the serum prostate - specific antigen (psa), the digital rectal examination (dre), and the ultrasound - guided systematic prostate biopsy sampling [24]. Although ov...
Herpes simplex encephalitis (hse) is the most common form of sporadic encephalitis worldwide and remains a disease with high mortality and long - term morbidity.1,2 if untreated, the mortality reaches 70%, and remains ~20% in the case of appropriate intravenous acyclovir treatment.3,4 at least 50% of hse survivors suff...
Although a history of head trauma is absent in 25 to 50% of these cases, mild head injury is the cause of most csdhs . Often trivial injuries, such as ordinary sports activities, riding a roller coaster or even head banging were reported as the trauma inducing csdh . We report a case of bilateral csdh after eccentric e...
We report a case of an adolescent sustaining bilateral femoral neck fractures due to a first time epileptic seizure, as a result of expansion of his known syrinx . A 19-year - old patient suffering from hypophosphatasia (hpp), arnold - chiari malformation, and a ventriculoperitoneal shunt sustained a trivial fall with ...
Extracorporeal shock wave lithotripsy (eswl) has revolutionized the treatment of noninfectious ureter and renal stones since the 1980s, and it is the least invasive treatment and most common intervention for upper urinary tract stones.1 advances in shock wave lithotripsy (swl) technology have improved treatment outcome...
Hydrogels are promising biomaterials extensively explored in both tissue engineering and drug delivery because of their hydrophilicity and biocompatibility . When the size of hydrogels is downscaled to the micro- and nanoregime, the resulting particles can potentially be engineered for intravascular delivery of therape...
Hypertension, or high blood pressure, affected 26.4% of the world's adult population (972 million) in 2000, and this rate is expected to increase to 29.2% (1.56 billion) by 2025 (1). Hypertension is a major contributor to the global disease burden and was responsible for 7.0% of all disability - adjusted life years in ...
More and more antitumor drugs have been discovered . However, the biggest problem is that these drugs could not efficiently exhibit their activity in killing tumors due to the difficulty in their ability to penetrate through the cell membrane. (1) synthetic cyclic peptide nanotubes are emerging as promising and selecti...
Osteoporosis is a devastating disease characterized by low bone density, microarchitectural deterioration of bone tissue, and increased susceptibility to fracture . Vertebral compression fracture (vcf) is a common manifestation of osteoporosis in the elderly with an incidence of 700,000 cases per year in the united sta...
Hemangioblastomas are highly vascular lesions, representing 1.5% to 2.5% of intracranial tumors and 7% to 12% of posterior fossa tumors hemangioblastomas are associated with intratumoral hemorrhage, which have been reported in only 4 arcticles . Both of the patients mentioned above presented severe symptoms and typical...
A 75 year - old male patient, who underwent endovascular repair of a 5.8 cm inflammatory abdominal aortic aneurysm two and a half years previously (fig . 1), was transferred from another centre complaining of acute abdominal pain and haematemesis of one day duration . He had several co - morbidities including chronic o...
Alpha-1-antichymotrypsin (act), also called serpina3, is a member of the serine protease inhibitor (serpin) family of acute phase proteins . Although act is predominantly produced in the liver, it is also synthesized in the brain, mainly by astrocytes . Elevated levels of act are found in the brain [3, 4], serum and ce...
Chronic heart failure (chf) is almost always characterized by impaired systolic and diastolic function and increased inflammatory activation . In addition, the inflammatory activation depends on the type of initial insult sustained by the myocardium . The increased production of pro - inflammatory cytokines, including ...
Accurate diagnosis of tumor, node, metastasis (tnm) staging and stage - based therapy is essential for the management of hollow viscus malignancy . Endoscopic ultrasound (eus) is the best modality for the delineation of gut wall layers and adjacent structures.1 for that reason, eus is well utilized for the evaluation o...
Scrapie is a naturally occurring progressive, fatal, infectious, and neurodegenerative disease of sheep and goats that has been recognized for over 250 years . The occurrence of scrapie preceded the recognition of other prion diseases of mammals and so can be referred to as the archetype of prion disorders . Like other...
Oral candidiasis, which is the most common human fungal infection, is characterized by an overgrowth of candida species in the superficial epithelium of the oral mucosa.1,2 it has been associated with multiple host risk factors, including impaired salivary gland function, denture wearing, oral mucosa disruption, drug u...
The enzyme phosphodiesterase 5 (pde5) hydrolyzes cyclic guanosine monophosphate (cgmp) to guanosine monophosphate (gmp), which functions in smooth muscle relaxation . Pde5 regulates cgmp levels, and inhibition of this regulator causes an increased level of cgmp, resulting in smooth muscle relaxation . Cgmp is expressed...
Four samples of pork liver sausage (designated sausages a d) collected at the final production stage from 4 independent manufacturers in 3 locations in southern france were found to be hev positive by using real - time reverse transcription pcr (rt - pcr). Samples were tested in 2 institutes, the animal health and vete...
Since superior mesenteric vein thrombosis (smvt) is a relatively rare disease and shows no specific symptom, its early diagnosis is reported to be difficult . In this report, we present a patient with acute appendicitis complicated by smvt and portal vein thrombosis (pvt) who followed an uneventful course after surgica...
Dental erosion is the loss of tooth substance by chemical processes not involving bacteria . Although a multitude of factors seem to be involved in this process, the most important factors are dietary acids and intrinsic acids from the stomach . Currently, the increased consumption of acidic foods and soft drinks is be...
Masking the bitter taste of drugs is a challenge in development of all oral formulations and a necessity to ensure better patient compliance and product value where the process and formulation should be economic, rapid, and easy, involving least number of equipment, and processing steps and minimum number of excipients...
Influenza viral infection causing severe ards is one of the leading causes of increased mortality in the recent years . Most patients who die due to influenza infection are because of severe hypoxia and multi - organ dysfunction syndrome (mods). In 2009 influenza pandemic, there was high mortality in patients with seve...
The human leucine - rich repeats and immunoglobulin - like domains (lrig) protein family comprises integral plasma membrane proteins lrig1, 2, and 3 . Lrig1 negatively regulates growth factor signalling and is a proposed tumor suppressor . In early stage uterine cervical carcinoma, expression of lrig1 has been associat...
These include aggravation of hypertension, retention of nitrogenous waste products, anemia due to erythropoietin deficiency, tendency to acidosis, and disturbed calcium - phosphorous - vitamin d metabolism that often leads to excessive secretion of the parathyroid hormone . Patients with chronic renal failure and patie...
The world s population is aging . On this basis, malaysia will be categorized as an aging nation over the next one decade or so . In 2008, the census for malaysia showed that 7% of its population were aged 60 years and above,1 and by 2020, it will increase to 9.5% of the country s population.2 the growth of an aging po...
The results of surgical treatment of epileptic seizures have improved in the past two decades, approaching 60% to 90% seizure - free outcome in patients with temporal lobe epilepsy and 40% to 60% in extratemporal lobe epilepsy.1 however, there are few alternative treatment options to patients who fail epilepsy surgery ...
Fibrinolysis takes place when undesirable fibrin is formed or when a hemostatic thrombus becomes unnecessary . Plasminogen activation by plasminogen activators (pas) is the initial step in fibrinolysis, which is regulated by many physiological and pathological factors so as to quickly dissolve unnecessary thrombi . Tis...
Acute decompensated heart failure (adhf) is one of the leading causes of hospitalization in the usa . Annually, more than one million patients are hospitalized with a primary diagnosis of heart failure (hf) in the usa.1 the majority of hospitalized patients with adhf will be readmitted with recurrent symptoms or will d...
Desmoplastic smallroundcell tumor (dsrct) is a rare, highly aggressive intraabdominal neoplasm with an extremely poor prognosis, first described in 1989 1 . It frequently occurs in the abdominal cavity and pelvis with an undetermined histologic origin, and its incidence in males (> 80%) and females differs 2, 3, 4, 5, ...
Cerebellar haemorrhage in preterm infants has become a focus of attention, as it is associated with neurodevelopmental sequelae and mortality [1, 11, 15, 17]. Prevalences ranging from 2.3% to 19% for very low birth weight infants (vlbw) have been reported [10, 15, 17, 21]. With regard to neurodevelopmental sequelae, ce...
Intracellular exchange is the essence of cellular life . For prokaryotic cells, simple diffusion of nutrients and waste products suffices . But for eukaryotic cells, whose functional organization relies on an elaborate network of intracellular membranes (also called organelles), a complex mass transit system has evolve...
Numerous cellular metabolic pathways, which include transcription and/or translation of dna, necessarily must respond to the local and temporal environment of the cell, and this necessitates a tightly controlled interaction between dna and these pathways and networks that act to regulate it . To respond quickly and pre...
As our society is growing older, the consequences of aging have begun to gain particular attention . Improvement of quality of life at old age and prevention of age - associated diseases have become the main focus of the aging research . In particular, skin aging has gained increasing interest, not only because it is t...
The mobile phone camera can be used to perform indirect ophthalmoscopy when used in conjunction with a + 20d condensing lens . However, the flash in most phones is not continuously on in the still photography mode, flash firing only during the exposure . In the video mode, the flash can be programmed to be always on wh...
In recent years, the use of skeletal anchorage for the orthopedic treatment of maxillary retrognathia has increased in order to avoid the dentoalveolar and skeletal side effects of tooth - borne devices and also to enhance maxillary protraction.1,2,3,4,5,6,7 de clerck et al.5 brought a new perspective to the orthopedic...
Opn is a secreted, integrin - binding glycophosphoprotein that was discovered independently in several different settings [1, 2]. It was identified as bone sialoprotein i, a major non - collagenous protein in bone, as a secreted protein produced by many transformed cells in culture and as a protein important for early ...
The success of the human genome project has clearly shown that the human genome encodes about 35,000 genes and over half of them are poorly understood proteins . A number of these proteins are thought to be related to pathological disorders and other biological phenomena, and thus, are potentially useful as therapeutic...
Tumor chronicity is a large and growing consideration as a result of successful treatment, the greater number of drugs available, and earlier diagnosis, which allow more effective therapeutic intervention . In recent years, with molecularly targeted drugs and a better understanding of the natural history of cancer, the...
Cryptococcosis is one of the most important systemic mycoses and is considered to be one of the three common opportunistic infections in hiv / aids patients, causing almost 625 000 deaths per year worldwide . The importance of cryptococcosis as an opportunistic pathogenic fungus has increased considerably over the last...
A crucial step for rational subunit vaccine design is the selection of antigens to include . For vaccines against infectious agents, antigens capable of inducing protective immune responses several strategies based on genomic and proteomic approaches are being used to identify subsets of antigens that are highly expres...
Changes in the modern medical science in 20 century have caused significant reduction of mortality, in contrast to past, that subsequently have caused every day increase of the elderly in the world (1, 2). Anthropologists have considered ages of 60 - 65 as entrance of the elderly period (3). According to official estim...
Elevations of aluminum in the human brain result in neither the neuropathology nor the clinical symptoms of ad . Examination of the neuropathological and neuropsychological findings from patients with long - standing abnormal elevations of brain aluminum indicates that there is no strong association between aluminum ex...
Idiopathic atypical haemolytic uraemic syndrome (ahus) is a rare disease, with an estimated incidence of two cases per million population in north america . It is characterized by thrombocytopenia, microangiopathic haemolytic anaemia with fragmented erythrocytes (schistocytes) and renal impairment . In the primary comp...
Cherubism is rare inherited condition affecting the jaws characterized by the replacement of normal bone by a proliferation of fibrovascular tissue containing multinucleated giant cells . An 8-year - old male child presented to our outpatient department with slowly enlarging painless, symmetrical swelling of the jaw . ...
Cytomegalovirus (cmv) has been established as the single most important pathogen after transplantation [13]. Several studies have shown that cmv reactivation from latency and primary infection shortly after transplantation are risk factors for both immunological rejection and mortality in the first year after transplan...
Advanced age is accompanied by a high prevalence of cardiovascular risk factors such as diabetes, hypertension and chronic kidney disease, all of which increase cardiovascular morbidity and mortality . The klotho (or more precisely alpha - klotho) has been identified as an aging suppressor protein, which is expressed p...
Gingival diseases are a diverse family of complex and distinct pathological entities found within the gingival, which are the result of a variety of etiologies . Gingival enlargement or overgrowth is one of the most important clinical features of gingival pathology . Gingival hyperplasia due to the concomitant unesthet...
Power wheelchairs (pw) are essential for many individuals who have mobility impairments and locomotion restrictions . Those who benefit from power wheelchairs improve and satisfy their functionality, increase participation in healthcare, education and social activities1 . Most wheelchair use occurring at home in a limi...
A neuropathy prevalence of 30% is reported in diabetic patients, estimating more than 50% could suffer from it during the course of the disease . Painful diabetic neuropathy (pdn) is one of the most common causes of chronic pain . Chronic pain affects 30% of the united states (us) population and has high treatment cost...
The study of complexity in ecosystems has been recognized as one of the frontiers of ecology . Many ecosystems exhibit remarkable complexity in both structure and dynamics, which has repeatedly frustrated attempts to predict the response of ecosystems to human interference . Complexity within ecosystems, however, has a...
Tori and exostoses are nodular protuberances of mature bone, the precise designation of which depends on anatomic location.1 torus palatinus and torus mandibularis (tm) are the two most common intraoral osseous outgrowths.2,3 tm is a bony protuberance located on the lingual aspect of the mandible, commonly in the canin...
Maltoma (lymphoma of mucosa - associated lymphoid tissue) of the gastrointestinal tract most commonly occurs in the stomach . Malignant tumors of the lymphoreticular system depress the body's t - cell immunity that may predispose the patient to several infections especially chronic ones such as tuberculosis . We presen...
Tracheoesophageal puncture (tep) with the insertion of voice prosthesis represents a useful and safe method for voice restoration after total laryngectomy . Most patients do well with tep, but a leakage of saliva or ingested food around the prosthesis does occur with the reported rate ranging from 7% to 42% of the case...
Enterorrhagia is a common sign in patients who come to a surgical department; after the exclusion of benign diseases (such as haemorrhoids, anal fissures or ibd), we focus on gastro - intestinal malignant tumours . However, even if colic or colorectal carcinomas are very common, the incidence of tumours of the small in...
Pancreatic ductal adenocarcinoma (pdac) is an aggressive cancer with a high incidence and mortality rate . The traditional treatment of pdac is surgical resection, with 5-year survival rate of less than 26% . Pdac is a malignant cancer with lesion extension, metastases to ln or liver, and contiguous organ invasion, lea...
This poverty - associated disease accounts for more than 200 million malaria cases annually reported between 2001 and 2012 in 104 endemic countries . Of the 104, 99 endemic countries with ongoing malaria transmission include 79 being in malaria control phase and the same 10 that achieved preelimination and elimination ...
The failing control of antimicrobial - resistant bacteria (amrb) is an important and continuously growing threat to the delivery of adequate medical care in hospitals and the community . Infections caused by amrb usually require longer and more complex treatments than those caused by susceptible bacteria [2, 3]. Nosoco...
It is becoming widely accepted that membranous nephropathy (mn) is an organ - specific autoimmune glomerular disease (1). Various forms of hypogammaglobulinemia including common variable immunodeficiency (cvid) can occur in patients with autoimmune diseases whereas persistent antigen stimulation due to defective immune...
All lenses were isolated from the donor no later than 8 hours post mortem, shipped frozen and stored at 80c before dissection . Fifty - five and 62-year - old human lenses were decapsulated and dissected into cortex (outer 0.5 mm of tissue), outer nucleus (approximately 1 mm wide ring inside of cortex containing adult ...
In plants, small regulatory rnas including mirnas, heterochromatic sirnas (hc - sirnas), repeat - associated sirnas (ra - sirnas), natural sense antisense transcript sirnas and trans - acting sirnas (ta - sirnas) are involved in regulating gene expression through various mechanisms (1). Recent studies have demonstrated...
Engineering of the rat cav1.3 long variant (1d, af370009.1) were made as follows . For fig . The dct of human 1f (np005174) was amplified and cloned non - directionally via the unique xbai site, yielding the sequence in supplemental 1.1 . For fig . S3.4, a like process was repeated, except appropriate sections of the d...
Intrathoracic hilar and/or mediastinal nodal enlargement in patients with concurrent or previously diagnosed extrathoracic malignancies is a common finding both by computed tomography (ct) or positron emission tomography - computed tomography (pet - ct). Nodal enlargement can be found at the time of the initial diagnos...
There are implications of recent global financial crises on financial and economic stability, and hence on food security because the global food system is very vulnerable . World economic forum report 2013 stated: global food and nutrition security is a major global concern as the world prepares to feed a growing popul...
Circadian rhythms in synthetic, metabolic, and proliferative functions characterize all organs, tissues, and cells . The mammalian central circadian clock, residing in the suprachiasmatic nuclei (scn), sets circadian clocks throughout the body through autonomic nervous connections, scn - orchestrated endocrine secretio...
Epithelial ovarian cancer (eoc) accounts for the majority of ovarian cancer and is the most lethal of all gynecological malignancies . It was expected that 21,550 new cases of eoc would be diagnosed in the us in 2009 and that 14,600 women would die from the disease . Although ovarian cancer accounts for only 3% of all ...
Whereas testicular appendix and testicular torsions are the most common causes of scrotal pain, acute epididymitis is considered to have an important role in children with scrotal pain . Previous studies have demonstrated that enteric organisms are a common cause of epididymitis in older men with benign prostatic hyper...
Tankyrases (tanks) 1 and 2 belong to the poly(adp - ribosylation) family enzymes and are soluble proteins that can bind to cytoskeletal, microsome and cytosolic proteins . A small fraction of tank 1 is localized at telomeres, where it regulates the accessibility of telomeric dna to telomerase . Tank 1 is required for p...
A 52-year - old female patient (height 160 cm and weight 60 kg) was scheduled for emergent hip arthroscopic synovectomy and partial labral resection due to acute hematogenous osteomyelitis with abscess . She had been npo for 14.5 hours before surgery . Upon arriving in the operating room, an initial systolic / diastoli...
Research can be defined as a detailed study of a subject, especially in order to find new information or to reach a new (better) understanding . Research in dentistry has increased rapidly in recent decades to improve the oral health for the overall health of the patients.1 since health researchers involve human partic...
Described neuroendocrine cell hyperplasia of infancy (nehi) in a study including 15 infants with symptoms of interstitial lung disease (ild), such as persistent tachypnea, retractions, hypoxemia, and crackles in the first year of life . The same authors had previously used the term persistent tachypnea of infancy for t...
Perhaps more than tens of thousands magnetic resonance images (mris) of brain are being examined and interpreted daily in all parts of the world . Usually in the axial mris, neurologists, neurosurgeons, and neuroradiologists are responsible for identifying each cerebral lobe and gyrus for localization of diseases . The...
Acute infectious diarrhea is a worldwide public health problem with a long list of differential diagnoses . In the us, major pathogens responsible for most cases include salmonella, campylobacter, shigella, escherichia coli o157:h7, and cryptosporidium . Vibrio, yersinia, listeria, cyclospora, clostridium difficile, gi...
The centers for disease control and prevention (cdc) has reported that the prevalence of diabetes (self - reported and undiagnosed) in the u.s . Is 10.2% for non - hispanic whites aged 20 years or older and 18.7% for non - hispanic blacks of the same age (1). According to the cdc, sufficient data are not yet available ...
A balanced and attractive smile is a primordial treatment objective of modern orthodontic therapy . Dentofacial appearance is one of the main determinants of physical attractiveness . During interpersonal interaction, individuals' focus is mainly centered on the other person's eyes and mouth, with little time spent on ...
The need for urgent large - scale action to counter climate change is well established, but anthropogenic emissions continue to rise ahead of the worst ipcc scenarios . The political and economic difficulties of implementing change are widely discussed, but even agreeing on technical implementation plans remains proble...
Standard automated perimetry (sap) has become the standard of care in assessing visual fields . We recently developed an eye movement perimetry (emp) test that uses an eye tracking system . Emp takes advantage of the natural reflex to direct our gaze with a saccadic eye movement towards a visual stimulus that appears i...
A 37-year - old serving army officer, a diagnosed case of schizophrenia for the last nine years, was on regular review and maintenance medication . Since he had two relapses due to poor drug compliance, he was on inj . Haloperidol decanoate every three weeks, and had achieved good remission . Since the last one year he...
A 5-month - old male child weighing 4 kg, having bilateral microcornea and total cataract, presenting with nystagmus, was planned for lens aspiration and intraocular lens implantation . Parents mentioned that the child had a history of recurrent cough; however, there was no history of hurried breathing, feeding difficu...
Communication between parents and their baby's principal medical care providers is important in the neonatal intensive care unit (nicu) setting . It is important for parents to feel that they can communicate with the doctors and neonatal nurse practitioners (nnps) in the nicu, so that they can understand their baby's c...
. The risk of fetal loss increases throughout pregnancy and may be higher in the second and third trimesters because the levels of some clotting factors (i, vii, viii, and x) increase, protein s (ps) and fibrinolytic activity decrease, and resistance to activated protein c resistance (apcr) develops . Mutations in the ...
Traditionally, the diagnosis of periapical lesions of the teeth has been based on clinical, radiological, and histopathological examinations . Conventional radiological procedures have limitations as they do not allow differentiation between cystic and noncystic periapical lesions . In view of this, usg has been used r...
We recruited 20 mfs patients (age = 30 12 [range = 1254, median = 26] years, male: female = 14:6) who had no history of aortic dissection and 12 normal subjects who had no history of cardiovascular disease (age = 26 8 [range = 2048, median = 23] years, male: female = 6:6). The bsa of each participant was calculated usi...
Pancreatic cancer is the fourth most common cause of cancer - related mortality in the united states. (1) the five - year survival rate is the lowest among all cancers, with estimates ranging from 0.4 to 4% . In 2007, an estimated 37 170 new cases of pancreatic were diagnosed, and an estimated 33 370 patients died as a...
Operons, consecutive genes in the same strand co - transcribed into a single messenger rna, were first described in the pioneering work of jacob et al . . The co - expression of genes in operons has well - known functional and regulatory implications (2). However, while in escherichia coli there is some evidence of co ...
As diffusing capacity of the lung has been used widely as one of the routine pulmonary function tests, many studies have been done to establish a standardized technique for examination and normal predicted values . Two methods for estimating dlco have been reported, one of which is the single - breath test, a modified ...
One disadvantage of these resins is polymerization shrinkage, which can lead to leakage of bacteria and fluid through the tooth adhesive and bracket - adhesive interfaces [1, 2]. Microleakage beneath the orthodontic brackets may be followed by enamel discoloration and decalcification as well as decreased bond strength ...
In a review in this issue of critical care, bopp and colleagues summarize current knowledge on the receptor of advanced glycation endproducts (rage) and its potential as a new therapeutic target in sepsis . Rage is expressed in many cell types involved in the innate immune system and is able to recognize a wide range o...
The presence of adnexal masses during pregnancy ranges from 1 to 81 to 1 in 2,500 pregnancies, but only 3% of these masses are malignant . Krukenberg tumor is an ovarian metastasis of a gastric tumor and accounts for 1%2% of all ovarian tumors . These tumors during pregnancy are even rarer, as the incidence of gastric ...