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World health organization (who) guidelines for pharmacological management of cancer pain consider that opioid analgesics are an established therapy for moderate - to - severe cancer pain.1 the european association of palliative care (eapc) recommends the use of morphine, oxycodone (oxy), and hydromorphone as first - li...
The chronic disease management network (cdm - net) project developed, implemented, and evaluated a broadband - based network of health services known as the chronic disease management service (cdms) for managing chronic disease, using type 2 diabetes mellitus (t2 dm) as the test disease . A number of electronic systems...
The complex but extremely ordered structure of the sarcomere is the elemental force - producing machinery of striated muscles . Recent studies of sarcomere assembly [1, 2], protein turnover [1, 3], and signalling cascades [4, 5] provide new insights into the spectrum of intermolecular interactions that support sarcomer...
Cis - diamminedichloroplatinum (cisplatin) is one of the most potent anticancer drugs and is widely used as the front - line therapy for the treatment of tumors of head, neck, lungs, and genitourinary tract . However, the clinical application of cisplatin is limited by its serious adverse effects, particularly irrevers...
Amliorer la scurit des patients grce des normes contemporaines et dtailles pour une pratique scuritaire de lanesthsie qui augmentent, amliorent et appuient les normes semblables dj publies par divers pays et procurent une ressource aux pays qui doivent encore laborer de telles normes . Linitiative mondiale une chirurgi...
Spondyloarthritis (spa) is a group of rheumatic diseases characterized by inflammatory back pain, peripheral oligoarthritis, enthesitis, and/or extraarticular manifestations1 . Ankylosing spondylitis (as) and psoriatic arthritis (psa) are the most frequently seen spa subtypes in rheumatology units2,3,4 . Foot involveme...
The budding yeast saccharomyces cerevisiae with its unparalleled genetic tractability has undoubtedly become the model of choice for large - scale studies on transcription, protein protein, and genetic interactions (suter et al ., 2006). Nevertheless, we are far from understanding biochemistry of all yeast gene product...
Inorganic hollow spheres of nanometer to micrometer dimensions represent an important class of materials, and are attended for wide potential applications, such as catalysts, fillers, coatings, and lightweight structural materials owing to their low density, large specific area, and surface permeability [2 - 5]. Especi...
When people originally from a lower altitude descend to sea level or lower altitude after high - altitude / hypoxia acclimatization, then they lose hypoxia tolerance and physiological adjustments . In addition, they experience changes in hemoglobin and hormone levels over time, and this is known as high - altitude deac...
New electronic devices and equipment lead to increased convenience in our lives . However, there is concern about possible hazards of the electromagnetic fields that these devices and equipment produce and their effects on human health . Electromagnetic fields have the properties of both electric and magnetic fields (m...
Obstructive sleep apnea (osa) is a major public health issue characterized by repetitive episodes of partial or total occlusion of the upper airway during sleep, causing exaggerated effort to breathe against the occluded airway, sleep fragmentation, and intermittent hypoxia.1 the effects of osa during sleep (especially...
The auricle, which is the part of the ear exposed to the outside, is important both functionally and esthetically.1 - 3) the skin of the auricle has little subcutaneous tissue, with the anterior surface having less subcutaneous tissue than the posterior surface, as well as being closely attached to the cartilage . Thes...
Reported complications after pbt are radiation - induced cataract and raised intraocular pressure (iop). Filtering glaucoma surgery has generally been avoided because of fears of seeding . A 37-year - old man presented with a self - discovered, pigmented lesion on his right iris . Four years later, the pigmented lesion...
Bacterial strains: in this study, we used 67 l. monocytogenes strains [15, 31, 34, 35]. These strains were isolated from skin of beef cattle from a japanese farm (five strains), japanese patients with listeriosis (seven strains) and meat produced in japan (37 strains) or imported to japan from other countries (18 strai...
Patients in the intensive care unit (icu) often have several organ abnormalities and physiological disarrangements that require highly complex and timely diagnostic tests and therapies.1 the first few hours after icu admission, where a patient s condition is stabilized and treatment plans are formulated, are crucial to...
Cardiac stress testing is the basic screening tool for ischemic coronary artery disease (cad). In the event of abnormal distribution of myocardial blood flow (or positive result indicative of functionally significant ischemia), coronary angiography is performed as the current gold standard in the diagnosis of ischemic ...
Dental erosion is a common problem in modern societies, owing to the increased consumption of acidic drinks, such as soft drinks, sport drinks, fruit juices, and fruit teas, which in turn have a high potential to provoke dental demineralization . Up to now, most clinical reports are generally related with a later inter...
Laryngotracheal separation (lts) is the most immediately life - threatening airway injury caused by any of various injuries to the neck including automobile accidents, attempted hanging, and direct blows to the anterior neck [1, 2]. Because lts is very so rare, emergency physicians and otolaryngologists have limited ex...
Klippel trenaunay syndrome (kts) is a rare congenital malformation first described in 1900 by maurice klippel and paul trenaunay . Kts is characterized by the triad of capillary malformations, atypical venous malformations and varicosities, and bony and/or soft tissue hypertrophy . Kts is estimated to affect 1 in 100 0...
Transition / transversion (ts: tv) biases observed in genome comparisons are potentially the result of mutational and/or selective evolutionary processes that influence the alteration of the two fundamental types of nitrogenous bases (i.e., purines and pyrimidines) that comprise dna . It has long been observed that (pu...
The increasing availability of the prostate - specific antigen (psa) screening test has led to earlier diagnosis of prostate cancer as well as to the promotion of more active treatment . Radical prostatectomy is one of the most common surgical methods for radical treatment of localized prostate cancer . Laparoscopic ra...
Since the discovery of a three - coordinate terminal nickel imido, (dtbpe)ni = nar (dtbpe = bu2pch2ch2pbu2, ar = 2,6-pr2c6h3, scheme 1a) in 2001, this class of complexes remains relatively scarce, and their reactivity remains underexplored . The low coordination geometry offered by the strong -donating and sterically e...
It represents about 7% of all soft tissue sarcomas and when it affects the skin, this tumor may be subdivided into two main categories: primary and secondary . Primary cutaneous leiomyosarcoma (pcl) of the skin is a rare soft tissue tumor that accounts for about 23% of all superficial soft tissue sarcomas . A 77-year -...
Although it is a relatively new modality, magnetic resonance imaging (mri) has emerged as a prominent noninvasive and nonradioactive imaging tool in diagnostic medicine and biomedical research . In general, the mri signal intensity (si) is a function of the water proton density of tissues under examination and the rela...
A report from taiwan showed that central nervous system infection and previous strokes are the two most common causes of se,4 while antiepileptic drug (aed) withdrawal and alcohol - related causes were leading causes of se in western countries.5 factors associated with poor outcomes of se were related to comorbid compl...
Severe cough or hyperventilation can increase the thoracic pressure, leading to an abrupt increase in alveolar pressure and consequent rupture of alveoli . Subsequently, the air that leaks out may reach the mediastinum via the pulmonary hilum and bronchovascular interstitium . Therefore, pneumomediastinum is a patholog...
Thrombotic microangiopathy (tma) encompasses a spectrum of diseases characterized by microangiopathic hemolytic anemia, thrombocytopenia and acute renal failure . Various treatment options have been tried for this condition, with varying degrees of treatment response . Here, we describe a case of gemcitabine - induced ...
Resonance raman (rr) spectroscopy has long been applied to monitoring the molecular dynamics of hemoglobin (hb). [13] this highly symmetric and chromophoric heme prosthetic group provides strong resonance enhancement, especially when in resonance with the intense electronic transitions centered at approximately 400 nm ...
Activation of the coagulation system is an important part of the systemic inflammatory response during infection . Lipopolysaccharide (lps), a complex outer membrane glycolipid of gram - negative bacteria, triggers an array of cellular activations through a variety of mechanisms involving diverse intracellular signalli...
In malaria holoendemic areas, where malaria is stable and intense throughout the year, morbidity and mortality from plasmodium falciparummalaria occur primarily in children aged 624 months and decrease significantly after 24 months of age . Age - related protection from p. falciparum infection and disease in these area...
In patients with mandibular retrognathism, it is difficult to establish a satisfactory esthetic profile,12 improve the respiratory function,34 and achieve stable treatment outcomes25 with orthodontic treatment alone . Surgical mandibular advancement with bilateral sagittal split osteotomy (bsso) or distraction osteogen...
Very recent studies in iran displayed the prevalence of the obesity, hypertension, and hypercholesterolemia are 30.9%, 23%, and 41.6%, respectively . The statin group of drugs is widely used to treat hypercholesterolemia in patients at cvd risk . Statins inhibit the rate - limiting enzyme in cholesterol biosynthesis, h...
Extensive evidence from studies employing a variety of mammalian species indicates that memory is organized in multiple brain systems that differ in terms of the type of memory they mediate (for reviews see squire et al ., 1993; packard and knowlton, 2002; white and mcdonald, 2002; squire, 2004). Neurobiological eviden...
Mouse embryos form five pairs of mammary rudiments (mrs). Their formation is preceded by the formation of three wnt10b - expressing mammary streaks in the axilla, inguen, and in between forelimb and hindlimb these streaks fuse into one continuous mammary line (ml) on each flank by e11.5, on which mrs develop in asynchr...
This article treats the rapid - equilibrium kinetics of the forward and reverse reactions of the enzyme - catalyzed a + b = p + q together and emphasizes the importance of reporting the values of the full set of equilibrium constants . A computer is used to derive rate equations for three mechanisms and to estimate the...
Spinal cord injury (sci) impairs a patient's motor, sensory, or autonomic system, and sci - related costs incurred by health care systems often burden society . Respiratory failure, cardiovascular dysfunction, thromboembolism, and autonomic dysreflexia are the common complications of sci . Furthermore, recent studies h...
Cerebral insults such as a traumatic brain injury (tbi), stroke, or status epilepticus (se) can lead to detrimental outcomes for patients who suffer from one of these events . All of these insults have been shown to cause acute cell death, disruption of the blood brain barrier, reduced neurological functional performan...
Beedis (or bidis) are the commonest smoked form of tobacco in india . According to the global adult tobacco survey, 34.6% of adults are current tobacco users . A greater proportion of males (47.9%) use tobacco compared to females (20.3%). Among females, while only 2.9% smoke any form of tobacco and 1.9% specifically sm...
Cavernous hemangioma constitutes 5 - 10% of vascular malformations occurring in the entire central nervous system (cns). Intraventricular location constituting 2.5 - 10.8% of cerebral cavernous hemangioma is uncommon because most of them are usually found in the parenchyme of cns4). So far, the intraventricular caverno...
In south africa, integration of services policy was enacted in 1996 with the aim of increasing health service utilization by increasing the accessibility of all services at primary healthcare level . However, the problem with the policy arises in the implementation of integrated primary healthcare as there is no agreed...
Obesity increases the risk of metabolic disorders, such as high blood pressure, type 2 diabetes, and fatty liver1,2,3 . It can also reduce skeletal muscle mass and exert a negative effect on normal muscle function4, 5 . Mammalian target of rapamycin (mtor), a serine / threonine protein kinase regulating the functions a...
Determinar si las caractersticas iniciales de los patrones individuales de la refraccin perifrica guardan relacin con los cambios subsiguientes de la refraccin, durante un periodo de un ao . Se reuni a 54 sujetos con miopa y emetropa (edad media: 24,9 5,1 aos; mediana: 24 aos) con visin normal, sometindoles a una refra...
The disrupted in schizophrenia 1 (disc1) gene is a 414.3 kb gene located on chromosomal region 1q42.2, and consists of 13 exons . Disc1 was originally identified as a candidate gene for schizophrenia in a large scottish family, in which a balanced translocation involving chromosomes 1 and 11 was strongly linked to schi...
Almost every type of animal cell has the capacity to synthesize heparan sulfate (hs). The hs polysaccharide is composed of alternating hexuronic acid and d - glucosamine units and is substituted with sulfate groups in various positions . The sulfated saccharide domains provide numerous docking sites for protein ligands...
Multiple myeloma (mm) is a clonal b - cell disorder in which malignant plasma cells (pcs) accumulate in the bone marrow, resulting in lytic bone lesions and excessive amounts of monoclonal proteins . Although therapeutic interventions have been developed, and the overall survival has been improved over the last decade,...
Although infrequent (1% to 4% in the first year), infective endocarditis may occur after aortic valve replacement.13 when present, prosthetic valve endocarditis is a severe problem that is associated with considerable morbidity, especially related to peripheral embolism, perivalvular abscess, and sepsis.49 acute corona...
An 8-year - old male siberian tiger at the budapest zoological and botanical garden had episodes of coughing in october 2001 . Because the coughing did not stop in 6 to 7 days, an expectorant (bisolvon; boehringer ingelheim vetmed gmbh . His condition showed a temporary improvement; however, after a few weeks, the anim...
A 48-year - old man presented with visual dimness in his right eye, which had developed over the two weeks prior to the visit to the ophthalmology clinic . His medical, family, and social history was unremarkable . His visual acuity (va) was 20/50 in the right eye (od) and 20/20 in the left eye (os). Dilated fundus exa...
Gastric cancer is the most prevalent malignant tumor and the second leading cause of cancer - related death in korea1). The benefit of systemic chemotherapy for treating advanced gastric cancer in the palliative setting has long been known . When compared with the best supportive care alone, combination chemotherapy yi...
Werner syndrome (ws) is an autosomal recessive disease that first captured wide attention due to its prominent premature aging (or progeroid) features . Ws is also of considerable biomedical science interest in light of the pairing of these progeroid features with constitutional genomic instability and an elevated risk...
Some ectoparasites of hedgehogs such as ticks and fleas have zoonotic importance (khaldi et al . Hedgehogs may act as reservoir hosts for some diseases for instance salmonellosis, leptospirosis and pulmonary capilloriois (mccarthy and moore 2000, riley and chomel 2005, marie et al . Ticks and fleas are blood feeding ar...
India has the world's highest burden of tuberculosis (tb). In india, the multidrug - resistant tb (mdr - tb) prevalence among all patients with tb combined is estimated to be 4.1% . A crude estimate derived from these data is that 4500 6000 hiv - infected persons develop mdr - tb annually in india . Diagnosis of any fo...
At the towards other earths ii meeting held in porto portugal in 2014 september, one theme emerged that bares directly on the subject of this paper . Intrinsic stellar activity (sa) has become the main limiting factor for planet searches in both transit and radial velocity (rv) data . Sa includes stellar oscillations, ...
Clinicians have been asking this question for 15 years now, and the answer is still unclear . Richard troughton and mark richards published a seminal paper in the lancet in 2000, in which they launched the hypothesis of guiding heart failure (hf) treatment with objective measurement of natriuretic peptides (nps). This ...
In the recent times, colon - specific technologies have utilized single or combination of the following primary approaches, with varying degrees of success: (1) ph - dependent systems, (2) time - dependent systems, (3) prodrugs, and (4) colonic microflora - activated systems [1, 2]. Among the different approaches to ac...
Recent diagnostic imaging tests such as computed tomography (ct) and magnetic resonance imaging (mri) contribute to improving the diagnosis of pancreatobiliary cancers [14]. However, from the point of cost benefit, it is not practical to perform these tests for all patients as screening . Thus, less - invasive and simp...
Streptococcus canis (sc) is a zoonotic pathogen that is transferred primarily from companion animals such as dogs and cats to humans through both animal bites and other mechanisms, and usually infects immunocompromised rather than immunocompetent hosts . This species has also been isolated from a variety of other anima...
Idiopathic osteolysis is a heterogeneous group of rare diseases in which there is a spontaneous, aggressive and extensive bone resorption . Idiopathic osteolysis was first described in 1838 and again in 1872 by jackson (1, 2) who reported a case of " boneless arm " . In 1955, gorham and stout (3) defined a specific dis...
To establish the desirable occlusion and articulation with proper inclination of teeth in deep - bite patients, orthodontic therapy alone is difficult and inefficient . Therefore, orthognathic surgical procedures, which reconstruct occlusal plane by aligning teeth or correcting skeletal deformities, are preferred to ob...
Avaliar a contribuio da anlise molecular do gene cystic fibrosis transmembrane conductance regulator (cftr, regulador da condutncia transmembrana na fibrose cstica) na investigao diagnstica da fibrose cstica em pacientes com suspeita de fibrose cstica (fc) leve ou atpica . Os voluntrios foram submetidos avaliao clnica,...
Prostate cancer is the most frequent tumor in men, afflicting african american males to a greater degree than caucasians . Morbidity and mortality are mainly attributable to metastasis; yet the mechanisms associated with progression are largely unknown . Localized carcinomas are readily removed surgically, but once a t...
In a 2009 report, the american association of medical schools (aamc) and howard hughes medical institute (hhmi) articulate goals for quantitative biology teaching that can serve as a starting point . Specifically, biology students should be able to demonstrate quantitative numeracy and facility with the language of mat...
Pleomorphic adenoma (pa) is the most common salivary gland tumor classified as benign epithelial tumors 1 . Various cell types can be seen in the tumor indicating a high occurrence of cell differentiation . The results suggested that wnt is involved in cell differentiation in pa . In the present study, we considered th...
The endothelium - derived relaxing factor, recently identified as nitric oxide (no) or a closely related compound, has potent antiatherosclerotic properties . No released from endothelial cells works in concert with prostacyclin to inhibit platelet aggregation; it inhibits the attachment of neutrophils to endothelial c...
A study data set of 817 cases with available oncotype dx test results (cases from 2004 to 2009, from magee - womens hospital of the university of pittsburgh medical center) was used to build the prediction models . All cases included in the study were sent for oncotype dx testing owing to clinical requests received by ...
In this prospective quasi - randomized, doubleblinded, placebo - controlled study, a total of 146 reproductive women aged between 18 - 35 years old who were referred to outpatient clinics of shahid beheshty and al - zahra hospitals from december 2009 to february 2010 for infertility treatments, having at least two of t...
Calcium has long been recognized as an essential intracellular messenger involved in many pivotal biochemical pathways . The biochemically relevant information attributed to this ionic species is believed to be encoded in the concentration and spatio - temporal properties of the calcium signal . The relationship that e...
The prevalence of congenital anomalies of the coronary arteries (caas) is reported to be approximately 0.2 - 1.4% in the general population . Of them, . It may be benign appearing as an incidental finding on routine coronary angiogram or sometimes, may be complicated with atherosclerosis and present with spectrum from ...
Hereditary dystrophies of the retina, such as retinitis pigmentosa (rp), are considerable causes of blindness in humans . Research efforts concerning these currently not treatable diseases are focused on the genetic background, the mechanisms of degeneration, and possible treatment strategies . Animal models in rodents...
Subjects between the ages of 30 to 49 years who received cataract surgery at st . Mary's hospital from 1995 to 2004 (n = 976) were included in this study . Patients with a history of ocular trauma, uveitis, ocular or systemic diseases other than diabetes and hypertension, congenital cataracts, and those who received co...
The prevalence of obesity has raised dramatically in recent years . Increased adiposity, particularly, visceral fat accumulation, is closely associated with premature atherosclerosis and many metabolic alterations including insulin resistance, dyslipidemia and hypertension .. obesity is one of the most common disorders...
Zinc oxide (zno) nanoparticles represent an important class of commercially applied materials . They have been widely applied in diagnostics, therapeutics, drug - delivery systems, electronics, cosmetics, personal care products, and food additives, due to their magnetic, catalytic, semiconducting, antimicrobial, ultrav...
Autotransplantation is the surgical transposition of a tooth from its original site to another extraction or surgically formed recipient site in the same individual . Autotransplantation is advocated in various conditions such as teeth with extensive caries, advanced periodontal diseases, congenitally missing, impacted...
Postoperative ileus (poi) is a transient impairment of normal gastrointestinal (gi) motility seen after major abdominal operations and periodically after nonabdominal operations, with characteristics including nausea and vomiting, bloating, abdominal pain and discomfort, absence of passage of flatus or stool, accumulat...
Within the next 20 years, it is anticipated that copd will rank fifth for overall causes of disability worldwide (murray and lopez 1996). Year 2000 statistics rank copd as the fourth most common cause of death in the us (minino and smith 2001). When considering smoking burden in the mortality rankings, copd rises from ...
The accurate duplication of the genome is critical to the survival of any organism . Dna damage, such as that caused by uv irradiation, can disrupt the replication machinery and prevent it from completing its task [1, 2]. In escherichia coli, a number of the cellular events associated with the recovery of replication f...
Subacute sclerosing panencephalitis (sspe) is a progressive inflammatory and degenerative disease of central nervous system caused by persistent infection of immune - resistant measles virus . The average period between exposure and onset of sspe ranges between 7 and 12 years . The typical clinical course of sspe is ch...
Children s oncology group (cog) member institutions care for the majority of infants, children, and adolescents with acute lymphoblastic leukemia in north america and oceania . Work by the legacy children s cancer group (ccg), dating back more than 40 years, serves as the foundation for many current cog trials . Studie...
To describe the anatomy and coronal alignment of the leg, a number of descriptive terms are used . The anatomical axis of each bone refers to a line drawn along the centre of the intramedullary canal . The mechanical axis of the femur refers to a line drawn from the centre of the femoral head to the centre of the knee ...
There are many reasons why researchers choose to publish the results of their research but one of the most important is to contribute to the advancement of medicine and science . When research involves human subjects, sharing results is more than a personal choice, it is an ethical obligation (1). Publishing results en...
Idiopathic thrombocytopenic purpura (itp) is an autoimmune disorder with a low platelet count characterized by premature platelet destruction and suppression of platelet production mediated by autoantibodies, which may predispose to bleeding.1) since severe bleeding is uncommon when the platelet count exceeds 30000/ul,...
Spirometry after bronchodilation is crucial in assessing the presence of airway obstruction, which is necessary for the diagnosis of chronic obstructive pulmonary disease (copd).1 chronic airway obstruction is mostly assessed using the ratio of forced expiratory volume in 1 second (fev1)/forced vital capacity (fvc) <0....
It is a potent opioid analgesic with ultra - short duration of action, extremely rapid peak effect, and an equally consistent and rapid elimination with complete cessation of effect within a maximum of 10 minutes . In clinical practice an excessive bolus dose however can cause rapid onset of potentially life - threaten...
Current rectal cancer treatment is based on a multidisciplinary approach entailing surgery, chemotherapy, and radiotherapy . The aim of surgery is to remove the rectum and the mesorectum contained within the intact fascia of the rectum . This technique reduces pelvic recurrence, prolongs survival, and preserves postope...
Patients with t2 dm and pll were identified by one of the authors (w.t.g .) In clinics sponsored by divisions of endocrinology or nutrition sciences at academic institutions during a 25-year period . Ten of these patients (half of the total) agreed to participate in metabolic studies on a research ward and constitute t...
Flu - like symptoms (including fever, severe headache, myalgia, chills, nausea and vomiting, conjunctival suffusion, abdominal pain, anorexia, coughing and sore throat) occur for more than 5 - 7 days . The second phase, immunologic, occurs immediately after the bacteriemic phase or 1 - 3 days after asymptomatic period ...
Coupling of metal on conventional polyethylene have been traditionally used as bearing surface of total hip arthroplasty (tha). However, this coupling could make debris of polyethylene resulting in an aseptic loosening over time is well known1). Previous other studies reported young age and increased activity levels as...
We describe three cases of submacular hemorrhage (smh) that occurred two to four days after anti - vascular endothelial growth factor (anti - vegf) intravitreal injection for occult choroidal neovascularisation (cnv) in age related macular degeneration1 (amd) and their management . Almost 2500 anti - vegf intravitreal ...
Teeth being the central component of the masticatory apparatus of the skull are good sources of material for civil and medicolegal identification . Teeth provide resistance to damage in terms of bacterial decomposition and fire when rest of body is damaged beyond recognition which makes them valuable tool in forensic i...
Retrotransposons are mobile genetic elements, closely related to retroviruses, which use their own proteins in conjunction with cellular machinery to replicate independently of the genome . The yeast retrotransposon ty3, and retroviruses such as human immunodeficiency virus type-1 (hiv-1), encode reverse transcriptase ...
Asthma is a complex and common disorder that is characterized by chronic inammation of the respiratory system, airow obstruction, and airway hyper - reactivity induced by certain stimulants, such as exercise, infection, allergens, and occupational exposures . As one of the most prevalent chronic diseases, asthma affect...
In the previous issue of critical care, rumpf and colleagues evaluated the potential contribution of measuring end - tidal carbon dioxide (co2) for suspected pulmonary embolism (pe) in the prehospital setting . Capnography has been studied for decades as a potential diagnostic tool for patients with suspected pe . Inde...
A 20-year - old virgin patient with an episode of massive menorrhagia at menarche was admitted to the emergency room (er) of the department of obstetrics and gynecology . Her medical history revealed that 15 days prior to the presentation at the emergency department, she had been prescribed a ten - day course of proges...
Coronal plane alignment of the lower limb is an important factor that affects implant stability and clinical outcomes after total knee arthroplasty (tka)1 - 3). Varus osteoarthritis of the knee is the most common indication for tka, which is accompanied with contracture of the medial collateral ligament and other media...
Despite well over 150 years of clinical use, a detailed molecular mechanism of anesthesia remains unresolved . The once prevailing hypothesis suggested that anesthetics worked through a nonspecific, membrane disruption mechanism, known as the meyer recent studies have shown that most, if not all, anesthetics affect a f...
Contrast - induced nephropathy (cin) was a common cause of acute kidney injury (aki). The prevalence ranged from 2% to 30% because of different studied cohorts (underwent diagnostic or therapeutic procedures) and cin definitions . Patients who developed aki after contrast medium exposure had markedly increased morbidit...
Bariatric surgery (bibp and agb) is routinely performed at the obesity centers of the institutions participating in this study . Patients are eligible for bariatric surgery if they meet the following criteria: 1865 years of age and a bmi> 40.0 kg / m alone or a bmi> 35.0 kg / m in the presence of comorbidities, plus a ...