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Normal tension glaucoma (ntg) is an optic neuropathy associated with glaucomatous optic nerve head damage, progressive retinal nerve fiber layer thinning, characteristic visual field defects, open anterior chamber angles on gonioscopy and maximum intraocular pressure (iop) below 21 mmhg . Glaucoma is a major optic neur... |
In the iranian traditional medicine, anbarnesa smoke derived from burning female donkey s dung has long been used for treatment of inflammatory ulcers and infections of the middle and external ear with no significant side effects . We conducted a systematic search in pubmed, medline, google, and google scholar database... |
A coronary artery fistula (caf) is an abnormal communication between one of the coronary arteries and a cardiac chamber or vessels, including the coronary sinus, pulmonary artery, or superior vena cava.1)2)3) caf is involved in 0.002% of general population and accounts for 0.4% of all cardiac malformation.4) caf mostly... |
Pregnancy does not translate to being medically compromised; therefore dental treatment should not be denied simply because a woman is pregnant . The pregnant woman who presents for dental care may require special considerations.1 therefore, the management of these patients may require adjustments in the timing and typ... |
Today, a large number of patients are searching for personal satisfaction and increasing the demand for an attractive smile . Tooth bleaching has become one of the most popular cosmetic procedures offered in dental practice.1 several products and techniques are available for vital tooth bleaching, and vary in concentra... |
Neuronal migration disorders are diseases that develop due to disruption of normal movement of postmitotic neurons from the ventricular zone to the cortical plate during embryogenesis that result in the total or subtotal absence of cortical sulci and severely disturbed architecture of the cortical plate . However, the ... |
The 20 century witnessed a myriad of advances in technology, which have found several applications in the field of medicine . Video technology was one of the most important factors that enhanced the ability of surgeons to perform complex laparoscopic surgeries . The advantages of laparoscopy were realized in adult surg... |
Copd is a common cause of disability, morbidity, and mortality worldwide and a major global health problem with enormous direct and indirect health care costs.1,2 the worst notice, however, is that the mortality rate (number of deaths per 100,000 persons) for copd in the last 50 years (at least in usa) has progressivel... |
Over the past decade it has been increasingly acknowledged that the understanding of metalorganic interfaces is crucial for further improving organic (opto)electronic and single - molecule devices . In this context, adsorbing organic acceptors or donors onto electrodes provides a convenient tool for modifying metal wor... |
The protective action of dietary fiber against colorectal cancer (crc) has been attributed to the fermentation of fiber by anaerobic bacteria in the colon, producing butyrate 1, an inhibitor of histone deacetylases (hdaci), which produces cell cycle arrest, differentiation, and/or apoptosis of crc cells 2 - 4 . Wnt act... |
An ectopic thyroid gland is defined as thyroid tissue that is not located anterolaterally to the second to fourth tracheal cartilages . Anatomically, an ectopic thyroid can be lingual (at the base of the tongue), sublingual (below the tongue), prelaryngeal (in front of the larynx), or can be found at other rare sites .... |
Drug abuse or dependence is derived from a set of factors including social and family issues, availability, and individual s disposition (1, 2). Personality is another factor that may play an important role in preparation, acceleration, or maintenance of drug abuse or dependence behaviors . Personality disorders are hi... |
Type 1 diabetes mellitus (dm) and graves disease are autoimmune diseases, and a number of genetic and environmental factors are thought to be involved in their etiology . We have demonstrated an association between both hla class ii genotype and ctla-4 (cytotoxic t lymphocyte antigen-4) gene polymorphism and childhood ... |
There have been numerous investigations of the effects of noise in neurobiological dynamical systems, for both single neurons and neural networks . A large number of interesting noise - related phenomena have been analyzed, including synchronization, stochastic resonance, and coherence resonance (reviewed in lindner et... |
The patient data analyzed in this study were obtained from the united kingdom glaucoma treatment study (ukgts). The ukgts was a randomized, double - masked, placebo - controlled, multicenter treatment trial for open - angle glaucoma . The study recruited newly diagnosed (untreated) glaucoma cases with glaucomatous visu... |
Hospitals are complex organizations which face a unique challenge in this ever changing economic environment: they need to increase the quality of care offered to their patients, while still reducing the specific associated costs . In this respect, many countries have set multiple forms of future funding policies to pa... |
Sepsis is a major healthcare problem . Despite advances in supportive care of critically ill patients, sepsis remains an important cause of death worldwide in adults and children [13]. The surviving sepsis campaign (ssc), which standardized the approach to sepsis, was recently updated . Several efforts have been made t... |
Laparoscopy is widely used as a tool in many clinical situations allowing for diagnosis and/or surgical management in a minimally invasive fashion . Nonetheless, attention to surgical technique is paramount to avoid both short and long term complications . A 32-year - old woman had a laparoscopy and a reported left sal... |
In 2009, the world health organization (who) published the surgical safety checklist (ssc) as part of their safe surgery saves lives campaign . The checklist was adapted from the field of aviation, where checklist use is standard practice . In aviation, checklists were developed in response to a crash involving an expe... |
Mitochondrial cardiomyopathy can manifest with various cardiac phenotypes, such as left ventricle (lv) hypertrophy, dilatation, wall motion abnormality, and lethal ventricular arrhythmia; these symptoms range from subclinical to critical conditions (1). The severity of myocardial dysfunction also predicts the prognosis... |
Micrornas (mirnas) are nonprotein coding rnas of between 20 and 22 nucleotides that attenuate protein production by cleavage, translational inhibition, or sequestering of mrna in p bodies . They are implicated in several different biological pathways, including plant and animal development, and cancer [24]. To better u... |
Muscle cramps are painful, local, tangible, and involuntary skeletal muscular contractions that usually affect leg muscles . Muscle cramps are one of the common symptoms of pregnancy, especially during the third trimester that are often unidirectional . Leg cramps mostly happen twice a week or less frequently, usually ... |
Protein phosphorylation can modulate protein activity, turnover, subcellular localization, complex formation, folding and degradation . Dynamic phosphorylation plays a pivotal role in almost all biological processes including cell division, differentiation, polarization and apoptosis . The importance of this post - tra... |
Severe acute respiratory syndrome (sars) is a new emerging infectious disease, which was first reported in china in 2002 and was rapidly spreading all over the world in 2003 [1, 2]. Patients develop persistent fever, dry cough, progressive radiographic changes of chest, and lymphopenia once infected . Despite treatment... |
Simultaneous cardiac and pericardial rupture secondary to blunt chest trauma is a highly lethal combination with a rarely reported survival . We present a young patient with a right atrioventricular groove injury, pericardial rupture and a unique and previously undescribed coronary sinus avulsion . A 17-year - old male... |
The nuclear condensation in sperm cells is due to the replacement of about 85% of lysine - rich histones associated with dna, with transition proteins that are rich in arginine and protamine . Contrary to histones, which form a ring with dna (nucleosomes), protamines are linked to the grooves of the dna helix, wrapping... |
The bureau of alcohol, tobacco, firearms and explosives (atf), a law enforcement agency within the united states department of justice, has been in the business of investigating the cause and origin of fires and explosions since the 1970s . Atf typically collaborates with other federal, state, and local authorities to ... |
Leiomyomatosis peritonealis disseminata is an exceedingly rare benign disorder characterized by multiple vascular leiomyomas growing along the submesothelial tissues of the abdominopelvic peritoneum . It is commonly described in women of reproductive age and is rarely seen in men and postmenopausal women . A 65-year - ... |
A 46-year - old female visited chonbuk national university dental hospital with the complaint of swelling in the left upper lip area . A clinical examination found a bony and hard gingival swelling that extended from the left maxillary incisors to the premolar regions, as well as displacement of the left maxillary late... |
Lupus nephritis (ln) is a major clinical manifestation of systemic lupus erythematosus that occurs in 15% of patients at diagnosis and in approximately 40% during the course of the disease . Renal biopsy is the gold standard for the diagnosis and follow - up, whereas the measurement of proteinuria identifies patients w... |
As a service to our authors and readers, this journal provides supporting information supplied by the authors . Such materials are peer reviewed and may be re - organized for online delivery, but are not copy - edited or typeset . Technical support issues arising from supporting information (other than missing files) s... |
In the last decade, the large availability of the internet and the embracing of new digital technologies like smartphones are changing people's way of life and introducing new social dynamics [1 - 7]. Social networks allow immediate communication with just one click, by searching, reaching and sending any kind of verba... |
, a wasting of bilateral leg muscles was evident, and she wore a foot brace . The motor weakness and wasting were more severe in the lower distal extremities than in the upper extremities . Muscular stretch reflexes were absent, and vibratory sense and pain appreciation were impaired distally in both upper and lower li... |
Mushrooms have been considered as ingredient of gourmet cuisine across the globe; especially for their unique flavor and have been valued by humankind as a culinary wonder . More than 2,000 species of mushrooms exist in nature, but around 25 are widely accepted as food and few are commercially cultivated . Mushrooms ar... |
Although various training modalities can be applied in patients with chronic obstructive pulmonary disease (copd) (eg, resistance, in - water, and tai chi), aerobic stimulus has been investigated in several studies, predominantly due to the ease of application, prescription and, consequently, monitoring of this trainin... |
Developmental dysplasia of the hip comprises of disorders of hip development that present in different forms at different ages . The common etiology is excessive laxity of the hip capsule, which fails to maintain the femoral head within the acetabulum . In newborns, the syndrome consists of instability of the hip such ... |
Originally recognized as a cause for oral candidiasis among hiv - infected patients reports of severe fungal infections caused by candida dubliniensis are emerging in recent years . C. dubliniensis shares many phenotypic characteristics with the predominant fungal pathogen candida albicans like the ability of germ tube... |
Herbal medicines are valuable and available resources of primary health care for thousands year in the traditional medicine including the thai folk medicine . Generally, the bioactive compounds in herbal medicines are secondary metabolites which act as various pharmacological properties.1, 2, 3 they are used as the sub... |
The world health organization projected that 300 million people will suffer from diabetes and 1.5 billion from hypertension by 2025 . According to the diabetes atlas 2006 published by the international diabetes federation, the number of people with diabetes in india currently around 40.9 million, is expected to rise to... |
Eczema is an inflammatory skin reaction characterized histologically by spongiosis with varying degrees of acanthosis . However, eczema is divided into two groups; exogenous eczemas, e.g. Contact dermatitis, are related clearly to defined external triggering factors, although inherited tendencies can also play a part, ... |
Crystals of angiotensinogen and the complex of human angiotensinogen with de - glycosylated renin - asp292ala were grown at room temperature under conditions listed in supplementary table 1 . Datasets were collected at 100k at the daresbury and diamond synchrotron light sources and processed with the ccp4 program suite... |
. A myoepithelioma classically presents as an asymptomatic mass that slowly enlarges over a long period of time . However, recurrent and malignant ones have also been described . They are more likely to occur in the parotid gland, but rare cases arising from minor salivary glands are also on record. [35] the authors pr... |
These properties help ni - ti instruments to negotiate and prepare curved root canals without early permanent deformation unlike stainless steel files . The ni - ti alloys used for manufacturing the endodontic files contain approximately 56% (wt) nickel and 44% (wt) titanium . Though niti instruments have many advantag... |
Diabetes mellitus (dm) increases the risk of heart failure development even in the absence of coronary artery disease, hypertension, or other comorbidities1, 2 and could result in a two to fourfold greater mortality in heart failure patients . Indeed, dm is capable of impairing the myocardial function: this is initiall... |
The development of artificial bioengineered constructs largely depends on adequate vascularization to guarantee sufficient oxygen supply . The arteriovenous (av) loop model is an established method to obtain transplantable bioartificial tissue in vivo . Originally based on the findings of erol and spira and subsequentl... |
Aging is associated with an increased risk of developing respiratory impairment1 . After a stroke, respiratory function lung function tests are not necessarily conducted in rehabilitation, sometimes because there is no examination equipment . (mainly for the pectoralis major muscle) is to improves the ratio of dyspnea ... |
Benign schwannoma is a slow growing encapsulated tumor arising from the neuroectodermal sheath of schwann . Approximately, 25 - 30% of all reported schwannomas occur in the head and neck and most of these in the eighth nerve . Schwannoma of the facial nerve is a rare entity with very few cases reported in the literatur... |
One - dimensional (1d) nanostructures such as wires, rods, belts, and tubes, whose lateral dimensions fall anywhere in the range of 1100 nm, have become the focus of intensive research, owing to their unique applications in mesoscopic physics and fabrication of nanoscale devices [1 - 6]. Among one - dimensional (1d) na... |
Mesoporous sba-15 silica molecular sieves of large pore diameter (up to 30 nm) and area (up to 1000 m g) show excellent homogeneity and stability and can be well controlled for adsorption / desorption processes . Mesoporous silica materials, especially mesoporous sba-15 molecular sieves, have been modified with 3-merca... |
This special issue of food biophysics journal contains papers originally presented at the 3rd international symposium on delivery in complex food systems, which was held at wageningen university, the netherlands, from october 18 to 21, 2009 . As the subtitle already indicates, the purpose of this symposium is to build ... |
The introduction of imatinib mesylate (glivec/gleevec, novartis, basel, switzerland) has improved outcomes for patients with advanced gastrointestinal stromal tumor (gist), and imatinib is now considered the standard first - line treatment in patients with metastatic or unresectable gist (1, 2). Imatinib is generally w... |
Cataract surgery with intraocular lens (iol) implantation is the most common ophthalmic surgical operation . The mean annual incidence of postoperative endophthalmitis (poe) among cataract patients ranges from 0.05 to 0.14% [15]. In practice, ophthalmologists apply topical antibiotic drops to prevent this rare but pote... |
It has been argued that the unaffected hemisphere may contribute to early recovery of motor function after stroke in humans1 and animals.2 a single session of somatosensory stimulation in the form of peripheral nerve stimulation improves motor function in chronic stroke.35 a decrease in short - interval intracortical i... |
Intravenous rtpa remains the only proven treatment for acute ischaemic stroke in the general population . Patients with end - stage renal disease (esrd) on dialysis have a 510-fold higher incidence of stroke than the general population with an overall incidence rate of 1333 per 1000 patient - years . This may reflect t... |
Point spread function (psf) is used to define the quality of a retinal image . When an eye is looking at a point source, the luminance distribution on the retina is called the psf . The visual acuity corresponds to the central part of the psf (0~1 min of arc), and the outer part of the psf (> 1) is the straylight . Str... |
Primary sjogren's syndrome (pss) is a relatively common autoimmune disease affecting 23% of the adult population . Undiagnosed pss presenting with severe hypokalemia and demyelination in the absence of dryness is rare but can occur in 27% . A 36-year - old lady presented with weakness of upper and lower limbs progressi... |
Reactive oxygen species (ros) are oxygen metabolites that are highly active in terms of oxidative modifications of cellular macromolecules including proteins, lipids, and polynucleotides . Superoxide radical (o2) is usually the primal ros species produced and is subsequently converted into hydrogen peroxide (h2o2) thro... |
In modern society, the incidence of cervical lordosis and thoracic and lumbar kyphosis is increasing, because many people maintain a fixed posture for long periods and number of aged people is increasing . An increase in thoracic kyphosis causes restrictions in chest expansion and respiratory muscle weakness, thereby r... |
Ethylcellulose, a nonbiodegradable and biocompatible polymer, one of the extensively studied encapsulating materials for the controlled release of pharmaceuticals, was selected as the retardant material for propranolol hydrochloride . Ethylcellulose, a polymer to microencapsulate a drug by coacervation phase separation... |
Preparation of solid dispersion of domperidone: domperidone inclusion complexes were prepared with -cd in different ratio (1:1, 1:2 and 1:3) by kneading method . Preparation of fast dissolving films: solid dispersion of domperidone and -cyclodextrin (1:3) was selected and dispersed in half quantity of water and to it m... |
Several cognitive domains, including attention, memory, and executive functions are impaired in bipolar disorder (1, 2). Meanwhile, in recent decades, there has been an increasing tendency to study neurocognitive deficits like executive functions among researches (3). Executive functions are a series of problem - solvi... |
Chronic hepatitis c virus (hcv) infection remains a global health threat with 175 million carriers worldwide . Approximately 3% of the worldwide population is infected with the hepatitis c virus (hcv). The prevalence of hcv infection varies throughout the world, with the highest prevalence reported in egypt . The natur... |
Epithelial - mesenchymal transition (emt) plays an important role in cancer tumorigenesis . During the emt, epithelial cells change their polarized epithelial phenotype to a spindle - shaped, myofibroblast - like phenotype with high motility, and cancer cells increased cell migration and invasion, which are crucial to ... |
In order to arrive at their conclusion that infanticide is morally permissible, giubilini and minerva espouse a personistic ethic . Briefly, this is the view that human beings do not have any inherent dignity in virtue of their humanity . Merely being human is not in itself a reason for ascribing value to someone . On ... |
A 10-month - old domestic shorthair cat was evaluated for severe esophagitis and protracted vomiting and regurgitation secondary to a sliding (type i) hiatal hernia . The hernia and concurrent upper airway obstruction (nasopharyngeal polyp) were diagnosed with a multi - modality approach, including thoracic and abdomin... |
The current criteria for diagnosis of amyotrophic lateral sclerosis (als) require neurophysiological evidences of ongoing denervation, defined by fibrillation potentials (fibs) or positive sharp waves, and of chronic partial reinnervation, involving enlarged, unstable motor units with a reduced interference pattern . F... |
Heparina, a highly sulfated glycosaminoglycan, has the highest negative charge density of any known natural biological molecule . Heparin has been extensively used as an injectable anticoagulant in many clinical procedures for the prevention of blood clotting, especially during open heart surgery [2, 3]. Pharmaceutical... |
Functional dyspepsia (fd) is a syndrome characterized by chronic and recurrent gastroduodenal symptoms in the absence of any organic or metabolic disease that is likely to explain the symptoms.1,2 fd is considered to be important to public health, because it is remarkably common, can be disabling, and can pose a major ... |
A septic patient is in your intensive care unit and you are concerned that he is behind on his intravascular volume . For a variety of reasons you have decided you would like to give him intravenous colloids . Frdrique schortgen and laurent brochard capillary leakage during sepsis is a reason for recommending the use o... |
Ten healthy volunteers participated in the study (9 females and 1 male, age: 2236). The study was approved by the central denmark region committees on biomedical research ethics (m-20100032). Written informed consent was obtained from the participants following oral and written information about the study . The exclusi... |
Delivery is a natural and physiologic process, but a painful and exhausting phenomenon both for mother and those who care her . This process constitutes a very important physiologic event of woman's life with significant physical, mental, and emotional effects . Delivery is accompanied by pain, mental stress, probable ... |
Injection use is one of the most important medical procedures used globally, mostly for administration of drugs and immunization . In a developing country like india unsafe injection practices put patients and healthcare providers at risk of infectious and noninfectious adverse events and have been associated with a wi... |
It implies tolerance to the semiallogeneic fetus, which possesses half maternal genes and half paternal genes . The more genetically distinct the fetus is, the greater the immunological tolerance becomes during pregnancy . This occurs during pregnancies by egg donation (ed), when the fetus is allogenic . Such tolerance... |
Ultrasound is routinely used to evaluate small breast masses . A large proportion of these small masses are benign but unfortunately many go to biopsy or excision despite benign imaging characteristics . Utilizing our case of adult male pilomatrixoma, we discuss the work - up of small breast masses, focusing on ultraso... |
Endovascular therapy for cerebral vascular diseases has expanded in both the variety and number of devices . Conventionally, an animal vascular model is used for initial testing of new devices.1 2 to date, swine and dog models have been reported.3 however, animal experiments are labor intensive and expensive . Fresh hu... |
One of every five children aged less than 5 years in low - income, developing countries is malnourished . Globally, undernutrition is associated with more than one - third of all deaths in this age group . Acute malnutrition defined by weight - for - height z - score (whz) <2 (i.e., wasting) in young children continues... |
Transplants of the retina are among the new strategies being used in the treatment of genetic and degenerative macular diseases . Moreover, literature dated from 2004 to 2011 was comprehensively examined via medline and pubmed searches for the following terms: auto-, homo-, heterologous transplantation, retina, stem ce... |
Pulmonary cryptococcosis is a type of fungal infection, initiated by inhalation of the organism, cryptococcus neoformans, from an environmental source (1). It most commonly occurs in immunocompromised hosts, such as human immunodeficiency virus (hiv)-infected or cancer patients, and rarely involves the immunocompetent ... |
Congestive heart failure is a leading cause of morbidity and mortality in developed countries, with an estimated prevalence of 1% to 2% in the general population, reaching 7% to 8% in individuals aged> 75 years.1 elevated blood pressure appears to play an important role in the pathogenesis of both left ventricular (lv)... |
Measurement of disease activity is critical for longitudinal assessments in both observational studies and clinical trials . In the field of rheumatology, more than 250 assessment tools have been developed and validated to evaluate pathology, symptoms, function, and health status of patients with rheumatic diseases . S... |
The cell morphodynamics underlying the processes that control the organized spatial distribution of cells during the embryonic development are nowadays largely unknown . A single fertilized egg - cell (zygote) undergoes cellular divisions, differentiations, and interactions giving rise to specific forms of tissues and ... |
Avian influenza (ai) is a highly contagious disease caused by type a influenza viruses, a member of the family orthomyxoviridae . Influenza a viruses have antigenically related nucleocapsid and matrix proteins but are classified into subtypes on the basis of their haemagglutinin (h) and neuraminidase (n) antigens . Alt... |
Bioflavonoids are a group of polyphenolic compounds that are common throughout the plant kingdom . They are widely studied and have been found to promote healthy living in epidemiologic studies . Much of the attention that bioflavonoids have attracted is due mainly to the french paradox . This is the dietary anomaly in... |
Ancient infection of germline cells with exogenous retroviruses established a genome - wide random embedment of proviruses, called endogenous retroviruses (ervs), and mendelian genetics governs their inheritance to the offsprings . Ervs are reported to exist in the genome of all vertebrates and constitute approximately... |
Fcs was used to determine the relative affinity of -syn100 for large unilamellar vesicles (luvs) composed of 100% popg or 1:1 (mol / mol) pg: pc under dilute conditions . Binding of fluorescently labeled protein to unlabeled vesicles results in a shift in the autocorrelation curves to the right (longer diffusion times)... |
Fibrillary glomerulonephritis (fgn), a rare glomerular disease was first described in 1977 . This rare entity is characterized by the presence of elongated, nonbranching randomly arranged microfibrils (1030 nm) in the mesangium and/or glomerular capillary wall . Ultrastructurally, the microfibrils seen in fgn are indis... |
Coagulase - negative staphylococci (cons), especially staphylococcus epidermidis, are considered as normal epithelial flora of every human in different parts of the body such as nares, head and axilla, with an essential role in maintaining the normal flora of healthy skin (1). S. epidermidis is also recognized as an im... |
Pemphigus vulgaris (pv) is a chronic autoimmune mucocutaneous disease that usually manifests first in the oral cavity and may later spread to the skin or other mucous membranes . Apart from ulcers, vesicles, bullae and pustular lesions, it can present solely as mucosal erosions . Herein we report a case of intraoral pv... |
. Basically, there are two different outcomes of drowning, death on the spot of drowning, and survival from the initial apnoea . However, with the lower respiratory tract challenged by water, the survivor may suffer acute lung injury (ali), which is characterized by developing pulmonary inflammation and edema . It was ... |
The success of contemporary and modern endodontics relies upon adequate knowledge of root canal anatomical variations and use of advanced diagnostic and treatment modalities . Recent studies and reviews have shown success rates up to 95% in teeth with irreversible pulpitis and 85% in teeth with necrotic root canals . M... |
Spontaneous pseudoaneurysm of the femoral artery is extremely a rare entity. (1) it can be secondary to the rupture of a true aneurysm, but in most events the cause is unclear. (2) most patients with non - atherosclerotic pseudoaneurysms of sfa are asymptomatic initially and later present with a pulsatile, expanding ma... |
Obesity is one of the most significant and rapidly increasing health problem today, giving rise to an explosion in health care costs . The amount of energy we consume and how much we move around are the key factors in body weight regulation, but why a positive energy balance emerges in the majority of individuals in so... |
In the aged one, the auditory loss, is one of the three more prevalent chronic conditions, being behind only of the arthritis and the hypertension1 2 . According to3, approximately 90% of the people with superior age the 80 years present auditory loss . When it occurs in function of the aging process it is known as pre... |
The transportation sector of the united states accounts for over 70% of the nation's total petroleum consumption, and 57% of the petroleum is imported . In addition, use of petroleum - based fuels contributes to accumulation of greenhouse gases (ghg) in the atmosphere . Due to concerns of energy security and ghg emissi... |
Osteopontin (opn) is a matricellular protein originally isolated from the bone, expressed by various cell types including macrophages, dendritic cells, and activated t cells . Opn mediates several biological functions such as bone remodeling, macrophage response, cell migration, and adhesion, and it is involved in the ... |
Chalcones (1,3-diphenyl-2-propen-1-ones) are known to possess a range of important biological activities, such as antibacterial, antifungal, antileishmanial, antimalarial, antifilarial anti - inflammatory [68], antiprotozoal (antileishmanial and antipanosomal), antimicrobial [1013], larvicidal, anticonvulsant, anti - h... |
The measuring health and disability in europe (mhadie) was funded as part of the 6th framework programme by the european commission to be developed between 2005 and 2008 . The main aim of the project was to demonstrate the feasibility and utility of the world health organisation s international classification of functi... |
The onset of seizures is usually before the age of 12 months in developmentally normal infants . The first seizure type is usually clonic, generalized or unilateral and triggered by fever . The diagnosis of ds is based on the clinical phenotype; however, mutations in the scn1a gene can be found in 7585% of patients wit... |
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