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Flow cytometry is a laser - based technology developed for the analysis of multiple physical and fluorescent parameters in cell populations . This technology works as suspended cells in a stream of fluid encounter a laser, exciting fluorescent markers on or within the cells . While flow cytometry has traditionally been... |
Edible bivalve molluscs may constitute a risk to food safety because, as filtering organisms, they are potential receptacles of pathogens, toxins and contaminants (huss et al ., 2000), so that classifying and monitoring fishery waters (latini, 2010) and the molluscs themselves is fundamental to ensure food safety in sh... |
A major challenge in the successful replantation / revascularization of an avulsed scalp is positioning of the patient's head during and after the operation, because: possibility of shearing between scalp and skull when the head is moved / rotated intra - operatively, leading to tearing of anastomosed vessels; andpost ... |
The technique described provides extracorporeal control of one limb of the suture and has the advantage of continuous tension application on both ends of the thread during knot formation . It is easy to learn, fast to perform, and no new equipment is used . The needle end is advanced through the trocar, and the free en... |
They are formed as earlier indicated as a result of aggregation of three or more molecules of surfactant existing in a particular liquid medium in thermodynamically stable equilibrium that create highly anisotropic interfacial region lining the boundary formed by polar aqueous and nonpolar hydrocarbon regions, impactin... |
United states committee on quality of health published a report in 1999 by the title of to err is human in which medical errors were mentioned as an epidemic problem leading to almost 44,000 - 98,000 deaths annually . This report was remarkable for who eventually leading to an announcement prioritizing patient safety a... |
The children prospectively observed in this study participate in the norwegian cohort entitled environmental triggers of type 1 diabetes: the midia study . The cohort was identified at birth from the general population based on genetic testing for the hla genotype conferring the highest genetic risk of type 1 diabetes,... |
Let g be a graph with vertex set v(g) and edge set e(g). The number of vertices of a graph g is the order of g and is denoted by n. on the other hand, the number of edges of g is the size of g and is denoted by e. we denote the degree of vertex v in g by dg(v). For two subsets s, tv(g), let eg(s, t) denote the number o... |
Because of an increased detection rate of small renal masses (4 cm or less), partial nephrectomy (pn) as a nephron - sparing surgery (nss) has been conducted in a number of centers as the gold standard of care . In cautiously selected patients with tumor sizes of <7 cm, pn can be considered feasible with superior renal... |
Ridi was set up in 1997 to coordinate registries for the incidence of type 1 diabetes in italy (17). All registries reported newly diagnosed cases of childhood type 1 diabetes using a special form, which includes each patient's personal identification number, date of birth, sex, date of diagnosis (defined as the date w... |
Clostridium difficile, a gram - positive, spore forming, and toxin - producing anaerobic rod bacterium, is the leading cause of hospital- and community - acquired antibiotic - associated diarrhea (aad) in the western world.1,2 c. difficile infection (cdi) is a growing worldwide health problem associated with substantia... |
This retrospective study included 112 eyes of 83 consecutive patients with mature cataracts who all had extracapsular cataract extraction with scoli between may and december 2008 . All surgeries were performed using topical anesthesia (proparacaine hydrochloride, 4 times in 15 min before surgery) by a single experience... |
Micrornas (mirnas) are small (2123 nt) non - coding rnas that are important regulators of gene expression . They act by base pairing with partially complementary sites in the mrna of their targets, and either inhibit translation into protein or decrease the stability of the transcript (1,2). The number of currently kno... |
After obtaining approval from the ethical committees of the forsyth institute and harvard school of dental medicine (hsdm, boston, ma, usa), both healthy and inflamed gingival tissue samples were collected in the periodontology department laboratories at hsdm . Healthy gingival tissue was characterized by the lack of b... |
Joint contracture causes functional disturbances in patients activities of daily living, decreased movement ability, and impairs the joint function, with high incidence1, 2 . Therefore, preventing the development of joint contracture is a key goal of physical therapists and rehabilitation specialists . Unfortunately, m... |
The study used data from the cross - sectional population - based 1998 singapore national health survey (nhs98; n = 4,723). Genotype data were available for 3,734 subjects comprising 2,520 chinese, 693 malay, and 521 asian indians . A total of 1,881 chinese subjects with normal glucose tolerance (ngt) had previously se... |
Iran is home to one of the world s oldest civilizations in southern and western asia . The 18th - largest country in the world in terms of area at 1,648,195 km, iran has a population of around 79 million . While the publication of scientific results is the main aim of research activity, scientometric methods (the study... |
Pharmacopuncture is a new acupuncture therapy based on a combination of meridian theory and herbal pharmacology . In pharmacopuncture, by injecting the extracts of herbs at acupuncture points, doctors gain a synergism of positive effects, i.e., a physical stimulation due acupuncture and a chemical effect due to the her... |
Congenital pericardial defects (cpds) are uncommon anomalies that are usually discovered unexpectedly by a cardiologist, radiologist, or surgeon . Occasionally, these defects may cause symptoms such as chest pain, dyspnea, arrhythmias, syncope, and even sudden death . Arrhythmias, including atrial fibrillation (af), ar... |
Hypertension (ht) is not an adult disease anymore; it is a silent disease that is generally asymptomatic in childhood and adolescent period . It plays the important pathophysiological role in the development of the reduction in baroreflex sensitivity and retinal alteration . Hypertension studies in children and adolesc... |
Artificial insemination by donor (aid) is a reproductive medical procedure for infertile couples that entails insertion of a fine catheter directly into the uterus to deposit a sperm sample from a donor with the aim of achieving pregnancy . Aid is used primarily in male spouses with incurable nonobstructive azoospermia... |
Brugada syndrome (bs) was first described in 1992 as a new autosomal dominantly inherited channelopathy caused by a defective gene located on chromosome 3 in a structurally normal heart . It is characterized by st - segment elevation in the right precordial leads and increases susceptibility to ventricular tachyarrhyth... |
Patients with end - stage renal disease (esrd), including those who are on peritoneal dialysis (pd), are at much higher risk for mortality than the general population . Several factors such as age, comorbidities including diabetes and cardiovascular disease (cvd), malnutrition / hypoalbuminemia, reduced residual renal ... |
Dry tap during sub - arachnoid block (sab) is a rare but troublesome incidence . The problem sometimes becomes difficult to solve or what to do next, kind of, due to its rare occurrence and sparse reporting . The annual incidence of spinal epidural abscess is 2.53 per 10,000 hospital admissions in the united states . W... |
Bacterial strains and growth conditions - c. diphtheriae strains used in this study and their characteristics are listed in table i. these microorganisms were maintained in trypticase soy broth (tsb) (bd difco, usa) at 37c and stored in the same medium with 20% glycerol . Escherichia coli top10 electrocomp (thermo fish... |
Guillain - barr syndrome (gbs) is the most common cause of acute neuromuscular paralysis . The most frequent variants of gbs include acute inflammatory demyelinating polyradiculoneuropathy (aidp) and acute motor axonal neuropathy (aman). Campylobacter jejuni infection precedes the onset of gbs in 26% of the cases in we... |
Tuberculosis (tb) is one of the leading infectious diseases worldwide and is still a serious public health problem in many countries . World health organization (who) estimates that one - third of the population is infected with tb and the infection rate increases nearly 1% per year . Tb is relatively common in pregnan... |
According to the recent united states (us) census bureau report, the older population (65 + years of age) is projected to increase to 88.5 million by 2050, which is more than double the population of elderly people (40.2 million) in 2010 . Due to the surge in the aging population, the us health care system will face in... |
Laparoscopic splenectomy was first reported by delaitre and maignien in 1991 and soon became a procedure adopted as golden standard for most indications for splenectomy for haematologic diseases . Advantages of laparoscopic splenectomy compared to the open procedure were demonstrated by many studies, including benefits... |
Toxic epidermal necrolysis (ten), also known as lyell's syndrome, is a widespread life - threatening mucocutaneous disease where there is extensive detachment of the skin and mucous membrane characterized by full thickness necrosis of the epidermis . Patients initially develop pain, tenderness or a burning sensation in... |
Easy fatigability is a problem commonly seen in modern society . Among fatigue - related disorders, chronic fatigue syndrome (cfs), which is defined by intractable physical and mental fatigue lasting more than 6 months with a number of accompanying symptoms, has been well investigated [2, 3]. In adults, several surveys... |
According to a recently released' the korean diabetes research report 2012' by korean diabetes association, one out of ten adults has diabetes disease, two out of ten have the impaired fasting glucose which is stage of diabetes, and three out of ten adults are threatened by high blood glucose . In addition, the aging s... |
The search for new drugs and protein reagents usually involves single organic molecules which attach to protein binding sites . Such studies are widely supported by computer - aided drug design tools [1, 2], however ongoing developments in supramolecular chemistry have directed the attention of researchers toward new t... |
Type 1 diabetes (t1d) is an autoimmune disease in which the immune system is activated against the insulin producing -cells present in the pancreatic islets . The elimination of these cells impairs the mechanisms that control the glucose blood level and, up to now, the possible and most efficacious treatment for t1d is... |
Elderly patients are at risk for falls, secondary fractures, hospitalizations, and death following hip fracture surgery.17 accordingly, it would be valuable to be able to predict complications and mortality after rehabilitation in the elderly with hip fractures . The norton scoring system is a well - known scale used b... |
As most of the dm - specific cutaneous disorders are related to the duration of diabetes and chronic hyperglycemia, a study of cutaneous disorders in patients attending diabetic clinic was undertaken to know the impact of control of diabetes on the pattern of these disorders . A cross - sectional descriptive study of 5... |
One of the most attractive subjects in tissue engineering is the development of a scaffold, a three - dimensional porous solid structure that plays a key role in assisting tissue regeneration . Ideally, a scaffold must be porous, bioactive, and biodegradable and possess adequate mechanical properties suited to the biol... |
The objective of this research was to estimate the unconfounded influence (either singly or in combination) of: (a) patient attributes (age, gender, race, and socioeconomic status) and (b) provider characteristics (physician gender and years of clinical experience) on medical decision making when providers are presente... |
Acute fibrinous and organizing pneumonia (afop) was first described by beasley et al . In 2002 as a condition characterized by alveolar damage, eosinophilic pneumonia, and organizing pneumonia . The features that distinguish it histologically are the presence of intra - alveolar fibrin balls, absence of usual hyaline m... |
Higher education in europe and in the balkan s countries is undergoing major reforms (1 - 3). Goals of the higher education transformation in europe was determined by the bologna declaration (signed in 1999 by ministries of 29 countries in europe) and sorbonne declaration signed on may 25, 1998 on harmonizing the archi... |
High frequency of established coagulopathy (30%) in multiply injured trauma patients has been reported, which accounts for up to 40% of all trauma - related deaths . The standard laboratory screening tests of coagulation are the prothrombin time (pt) and activated partial thromboplastin time (aptt), which can be affect... |
The demand for having more esthetic teeth and restorations has led several studies to be done in the field of tooth bleaching and its effects on the properties of teeth and the quality of composite restorations.12 while altered surface texture, hardness, fracture toughness34 and increased surface roughness of enamel,5 ... |
Cancer is a major social problem, and it is the main cause of death between the ages 4565 years . In the treatment of cancer, hadron therapy, thus, has great prospects for being used in early stages of tumor disease not amenable to surgery . Light particles are often used for radiation therapy because they have a well ... |
Protein - based therapeutics such as antibodies, blood derived products, and vaccines have been widely investigated in the past decade to treat a variety of disorders . Development of a nanoparticulate - based dosage form of these molecules is still considered as a major challenge by scientists in the drug delivery fie... |
We focused on the geographic range of denvs in latin america and the caribbean, where dengue is widespread and expanding in range . We attempted to identify areas contiguous with previously known dengue - endemic zones where new denv transmission is occurring by using reports of recent outbreaks . Known dengue - endemi... |
Melatonin, the main product of the pineal gland, is found in high concentrations in other body fluids and tissues [1, 2] and possesses anti - inflammatory and antioxidant actions [36]. We have evaluated the prophylactic as well as the therapeutic effect of melatonin in heatstroke rats under general anesthesia and showe... |
The goal of implantation of multifocal intraocular lenses (miols) is restoration of vision over a range of distances and reduction of spectacle dependence after cataract surgery . Miols generally provide vision at various distances by either concentric rings with different focusing powers (refractive miols) or division... |
Portal hypertension is the most common complication of chronic liver disease, leading to the development of ascites, portal - systemic encephalopathy, and gastroesophageal varices . Hemorrhage from gastroesophageal varices is among the most lethal complications of cirrhosis and portal hypertension . Esophageal varices ... |
Arterial dissection is the second leading cause of stroke in patients younger than age 45 (lisovoski and rousseaux, 1991). Current endovascular recanalization approaches for acute stroke focus on either removal of the distal clot using either a retrieval device or aspiration, or displacement via angioplasty and/or self... |
Pulmonary sclerosing hemangioma (sh) was first described by liebow and hubbell in 1956 (1). Sh is thought to be a rare benign neoplasm, but it has uncertain histogenesis and biologic behavior . Sh comprises a mixture of four histologic patterns, such as papillary, sclerotic, solid and hemorrhagic . Sh consists of two c... |
Microorganisms such as bacteria and viruses have several components called pathogen - associated molecular patterns (pamps). Pattern recognition receptors (prrs) of host innate immune system such as tlrs can recognize these components during infections (1, 2). Toll - like receptor proteins are members of a big family, ... |
Hypertension is an important worldwide public health problem and is a major risk factor for cardiovascular disease, the leading cause of death and disability worldwide . Testing for hypertension is the most commonly performed screening test in medical practice and is important not least because individuals with a norma... |
Before the 1970s, the majority of high - grade musculoskeletal tumors involving the distal femur were treated with transfemoral amputation owing to an unacceptably high rate of recurrence associated with local resection [10, 19, 31, 47]. As effective chemotherapeutic regimens were developed, limb salvage using various ... |
Reversible posttranslational modification by ubiquitin and ubiquitin - like proteins (ubls) plays a crucial role in dynamic regulation of protein function, fate, binding partners, activity, and localization . Small ubiquitin - related modifier (sumo) is a member of ubls family that is covalently attached to lysine resi... |
Lung cancer is the leading cause of cancer - related mortality in both men and women throughout the world . It is also the most commonly diagnosed cancer worldwide with most of them at an advanced stage with a poor prognosis . A 78-year - old male smoker patient diagnosed to have non - small cell lung cancer (nsclc), s... |
Traumatic intracranial pseudoaneurysm is a rare condition, accounting for less than 1% of all aneurysms.7) of these, post - traumatic vertebral artery pseudoaneurysm is not well known, because the incidence of isolated trauma to the vertebral artery is extremely low . Majidi et al.4) reported that incidence of vertebra... |
It is personal, highly transportable, and widely used, particularly in the western countries (1, 2). However, text messaging coupled with specific management strategies has yet to be utilized effectively in developing countries with high prevalence of diabetes . Several studies showed that mobile phone might offer a us... |
A review of epidemiologic studies demonstrates a prevalence of co - morbid depression in a range of 6%80% of copd patients, with an average among the majority of the strongest studies of approximately 40% . This compares to a rate of 15% in the general population (light et al 1985; van ede et al 1999; yohannes 2000; ay... |
Water can be found everywhere in nature in each three states (solid, liquid, and gaseous). Base of liquid dosage forms is almost exclusively water, but it can be found in half - solid dosage forms, such as hydrophilic ointments, as well . In the case of solid dosage forms usually it is essential to keep the water conte... |
Congenital dyserythropoietic anemias (cdas) are inherited disorders that result from anomalies during the final stages of erythropoiesis and consequently present defective production of red blood cells 1 . Cdas are characterized by chronic hyporegenerative anemia with inadequate reticulocyte count for the degree of ane... |
The incidence of post - operative morbidity and mortality is higher in geriatric patients owing to the increased incidence of complications such as myocardial ischaemia (mi), stroke, dementia, renal dysfunction, pulmonary embolism (pe) and other respiratory complications . Beta blocker usage, deep vein thrombosis (dvt)... |
Fish has been and will continue to be one of the major sources of animal protein for humans . It will likely become more important as the population heads towards 8 billion in about 20 years as food production (e.g., growing of crops, breeding of domestic animals) has and will continue to compete with other human activ... |
The mucosal surfaces of our body are a primary component of our innate immune system and serve as a barrier against endogenous microflora as well as against external pathogens . This barrier is made of polarized epithelial cells, specialized immune cells, and secreted mucus . Many pathogens have evolved strategies to c... |
From march 1997 to 2010, a total of 114 cases of malarplasty with l - shaped osteotomy through intraoral approach were performed, including 103 cases for women and 11 cases for men, with ages ranging from 16 to 48 years, all caused by congenital abnormality or heteroplasia . Measurement of the ratio between the facial ... |
This study aims to determine the frequency of opthalmyomyiasis externa and the ocular findings of disease in southern khorasan . All patients referred to the emergency department of valiaser hospital during the year 2011 with external ophthalmomyiasis were enrolled in this study . The diagnosis of external ophthalmomyi... |
Mononuclear cell recruitment, one of the hallmarks of allograft rejection 12, is thought, conceptually, to follow the now classic sequence of leukocyte rolling along vascular endothelium, followed by stimulus - dependent attachment, triggering and transmigration, and directed migration along a chemotactic gradient 3 . ... |
An expert consultation organized by the world health organization in 2005 made an inventory of available research on births spacing . The experts recommended an interpregnancy interval (ipi) of at least 6 months after a miscarriage before attempting a next pregnancy, in order to reduce morbidity and mortality risks for... |
The study was approved by the emory university institutional review board and used data from 1,573 adults in the sigt study, described previously (5). Briefly, this study recruited participants without known diabetes between january 2005 and march 2008 . The participants first visits were at different times of the day,... |
Parasites are eukaryotic pathogens, and broadly comprise protozoa, fungi, helminths and arthropods (figure 1) that complete part or all of their life cycle within a host organism . Like other pathogens they succeed in this through a great diversity of strategies for avoiding immune detection, suppressing cellular immun... |
Xenon anesthesia allows a fast recovery of cognitive functions and provides cerebral protective effects in experimental models [2, 3] these advantages suggest that xenon may be an attractive alternative to the various techniques of general or regional anesthesia [5, 6] usually proposed during carotid surgery . Measurem... |
Solid pseudopapillary tumour (spt) of the pancreas is one of the rare found primary tumors of the pancreas, making up approximately 0.172.7% of cases . There have been controversies regarding the terminology and according to its macroscopic and microscopic pathological characteristics over the years . It has been given... |
Emphysematous urinary tract infections (utis) are infections associated with gas formation that may present as cystitis, pyelitis, or pyelonephritis . Uncontrolled diabetes mellitus is a major risk factor for this type of infection, as it provides a favorable microenvironment for the gas forming organisms to grow, . We... |
Meningeal hemangiopericytoma (mhpc) was first reported by stout and murray in 19422832). Mhpc tumors arise from zimmermann's pericytes around capillaries and post - capillary venules . Begg and garret have reported several similarities between mhpc and angioblastic meningioma, and have additionally used immunohistochem... |
Rheumatoid arthritis (ra) is a disabling and progressive chronic autoimmune disease that carries a significant burden.1 although ra affects people of all ages, its prevalence increases with increasing age and it is more common in women than in men.2,3 a prevalence of 0.5%1% and a mean annual incidence (ie, rate of new ... |
Chronic hepatitis b (hbv) and c virus (hcv) infection are major causes of morbidity and mortality in the united states (us). It is estimated that approximately 1.3 million and 5.2 million people in the us suffer from chronic hbv and hcv infection, respectively.1,2 both chronic infections can lead to cirrhosis, hepatoce... |
Arthroscopic fixation of tibial spine fracture without damage to the growth plate is very important in patients with open physis . The present article describes a simple and effective technique being used for the first time to treat this condition . A 16-year - old boy sustained avulsion fractures of tibial spine while... |
Volume repletion in the acutely hypovolemic injured patient is essential for maintaining perfusion to critical organs . Traditionally, this has been achieved through the infusion of isotonic crystalloids, sometimes in massive quantities . However, it is increasingly recognized that overzealous crystalloid administratio... |
Many therapeutic measures such as chemical peeling, subcision, dermabrasion, fillers and punch techniques have been performed to improve acne scarring but with sub - optimal outcomes . Ablative lasers such as er: yag lasers or co2 lasers produce significant improvement at the cost of long recovery times and post - infl... |
With the increase in international travels and multiracial communities in the united states, non - rubella immune (nri) pregnant women as well as nonimmune individuals are at risk of rubella infection . A study in 1988 suggested that between 7.5 and 17.4% of pregnant women in the united states lack immunity to rubella ... |
With the exponential rise in health care costs, health care authorities worldwide are expressing the urgent need to obtain information on health care performance . Evidence has suggested that the dissemination of data on performance can lead to improvements in the quality and efficiency of health care services . The mo... |
Gene therapy for x - linked severe combined immunodeficiency (scid - x1) has been successfully employed in the clinic by restoration of c expression in bone - marrow - derived cd34 cells using integrating vectors.1, 2 in the earliest studies, using conventional -retroviral vectors, robust immune reconstitution was obse... |
Uterine cervical cancer is one of the most common cancers diagnosed in women of reproductive age . Thanks to the progress of the cervical cancer screening system, the mortality rate of patients with cervical cancer has decreased in japan over the past twenty years1 . However, the number of patients with early invasive ... |
End - stage renal disease (esrd) is a growing public health problem and one that has a significant impact on the lives of patients . There are multiple sources of stress associated with the loss of kidney function and reliance on a multifaceted treatment regime . The reliance upon dialysis is one of these stressors, wi... |
Bacteria were found in dentinal tubules of root canal dentine in histological sections of infected teeth and apical portion of root canal is an area of interest that may harbor a critical level of microorganisms, which is effective on apical periodontitis . Although cleaning of recessed surfaces is based more on irriga... |
The advent of a biological marker that reliably indicates the presence of alzheimer disease (ad) and distinguishes the latter from other dementing disorders would greatly assist the medical management of this common neurodegenerative condition . The successful integration of such a marker in routine clinical practice w... |
A 22 weeks pregnant woman came to us for advice regarding the chance of offspring getting retinoblastoma as her first child had bilateral retinoblastoma . The other offspring was 1 year and 9 months old at the time of presentation with a history of leukocoria in the left eye . She was diagnosed to have bilateral retino... |
Strabismus is a very common eye disease characterized by abnormal eye movements . According to fu et al,1 the prevalence of strabismus was 108 out of 2,260 (5.0%) eligible students in the central china . Strabismus is not only a cosmetic disease but also causes severe damages to visual acuity (va), binocular vision, an... |
With recent trends and technology advancement in the development of converged broadband next generation networks (ngns) and advanced multimedia services, the potential has increased for delivering various e - health services to end users anywhere, anytime . The term e - health has been used to refer to the use of infor... |
Negative pressure pulmonary edema (nppe) is an uncommon, but potentially life - threatening complication of general anesthesia . It is usually seen during emergence from anesthesia . In healthy adults undergoing general anesthesia, the incidence of nppe is 0.05 to 0.1%. [13] it is even less common with the use of a lar... |
About a decade ago most healthcare professionals had never heard the term human factors . Even today it is still not as familiar to many clinicians as most human factors experts would like to think . Nevertheless significant progress has been made in human factors science as well as in applications of human factors con... |
It is acquired by the consumption of raw or uncooked pork products containing encysted larva . Arthralgias and cardioneurological symptoms occur rarely, but the parasite has not been known to directly infect the bone . Pyomyositis is primary infection of the skeletal muscle, usually caused by staphylococcus aureus, and... |
The intermolecular amidoalkylation reaction is a very useful carbon carbon bondforming process in organic chemistry.1 it has been widely applied to the stereocontrolled functionalization of nitrogen heterocycles, as the reaction of the cyclic nacyliminium ion intermediates, generated in situ, is usually highly diastere... |
Malaria, caused by protozoan parasites of the genus plasmodium, is one of the leading causes of illness and death worldwide . Its effects are exacerbated by its ability to modulate immune responses, which not only impairs the patient's ability to fight the malarial infection, but can leave them vulnerable to some secon... |
The most common serious pneumococcal disease is pneumonia, an infection of the tissues of the lungs . Pneumococci may also cause infections in the ear (otitis media), para nasal sinuses (sinusitis), the tissues covering the brain and spinal cord (meningitis), and, less often, the heart valves, joints, and abdominal cav... |
Iron metabolism is implicated in the incidence of diabetes and associated atherosclerotic disease [13]. This causative relationship is underlined by reports of an improvement of glycaemic control in response to a reduction in body iron [4, 5]. Body iron stores accumulate by dietary factors that include vitamin c and al... |
Caring for children with special health care needs (shcn) may take a toll on parental health, divert attention from typical aspects of family functioning, and can also influence possibilities for participation in paid employment (derigne, 2012; hauge et al . Children with shcn often have a substantial need for professi... |
Gastric cancer is one of the most frequently diagnosed malignant neoplasms and has the second - highest cancer - related mortality rate in the world . In east asia especially, like china, japan, and korea, more than one million new cases are diagnosed each year . Most patients with gastric cancer are diagnosed at advan... |
Leptomeningeal carcinomatosis is a rare but fatal manifestation of metastatic breast cancer, with limited treatment options . Median overall survival of untreated patients with leptomeningeal carcinomatosis is only 4 - 6 weeks . Although the prognosis for patients with breast cancer and leptomeningeal carcinomatosis is... |
Sweat gland carcinoma (sgc) is a rare tumor particularly over scalp, which was reported first in 1865 . The treatment of choice is wide excisional biopsy, with extensive excision and regional lymph node dissection . We report a case of 42-year - old female with ulcerative lesion over scalp since 6 months proved as sgc ... |
The mean age at onset was 34.3 years (range, 6 months to 64 years). We conducted mutation screening, performing pcr amplification of the entire park2-coding region and exon - intron boundaries, using the hotstartaq master mix kit (qiagen, venlo, the netherlands), followed by bidirectional direct sequencing with the big... |
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