pdb stringlengths 4 4 | Hchain stringclasses 59
values | Lchain stringclasses 60
values | model int64 0 76 | antigen_chain stringclasses 386
values | antigen_type stringclasses 24
values | antigen_het_name stringclasses 240
values | antigen_name stringlengths 1 396 ⌀ | short_header stringclasses 448
values | date stringlengths 8 8 | compound stringlengths 4 243 | organism stringlengths 3 175 ⌀ | heavy_species stringclasses 121
values | light_species stringclasses 67
values | antigen_species stringclasses 937
values | authors stringlengths 6 762 | resolution stringlengths 1 8 | method stringclasses 10
values | r_free stringclasses 354
values | r_factor stringclasses 342
values | scfv bool 2
classes | engineered bool 2
classes | heavy_subclass stringclasses 14
values | light_subclass stringclasses 35
values | light_ctype stringclasses 3
values | affinity float64 0 0 ⌀ | delta_g float64 -16.91 -5.04 ⌀ | affinity_method stringclasses 11
values | temperature float64 4 37 ⌀ | pmid stringclasses 157
values |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
7mly | F | K | 0 | D | E | protein | protein | NA | NA | glycine receptor alpha 1 | glycine receptor beta | MEMBRANE PROTEIN, SIGNALING PROTEIN | 04/29/21 | Cryo-EM reveals partially and fully assembled native glycine receptors,heteromeric pentamer | RATTUS NORVEGICUS; SUS SCROFA | rattus norvegicus | rattus norvegicus | sus scrofa | sus scrofa | Zhu, H., Gouaux, E. | 2.7 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV6 | Kappa | null | null | null | null | null |
7lg6 | H | L | 0 | A | protein | null | envelope glycoprotein gp120 | VIRAL PROTEIN/IMMUNE SYSTEM | 01/19/21 | BG505 SOSIP.v5.2 in complex with VRC40.01 and RM19R Fabs | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS; MACACA MULATTA | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Cottrell, C.A., Torres, J.L., Wu, N.R., Ward, A.B. | 3.28 | ELECTRON MICROSCOPY | null | null | false | true | unknown | unknown | unknown | null | null | null | null | null |
3hi6 | X | Y | 0 | B | protein | null | integrin alpha-l | cell adhesion/immune system | 05/19/09 | Crystal structure of intermediate affinity I domain of integrin LFA-1 with the Fab fragment of its antibody AL-57 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Zhang, H., Wang, J. | 2.3 | X-RAY DIFFRACTION | 0.226 | 0.170 | false | true | IGHV3 | IGKV1 | Kappa | 0.000005 | -7.26 | SPR | null | 19805116 |
1mjj | H | L | 0 | H | Hapten | HAL | N-{[2-({[1-(4-CARBOXYBUTANOYL)AMINO]-2-PHENYLETHYL}-HYDROXYPHOSPHINYL)OXY]ACETYL}-2-PHENYLETHYLAMINE | IMMUNE SYSTEM | 08/28/02 | HIGH RESOLUTION CRYSTAL STRUCTURE OF THE COMPLEX OF THE FAB FRAGMENT OF ESTEROLYTIC ANTIBODY MS6-12 AND A TRANSITION-STATE ANALOG | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Ruzheinikov, S.N., Muranova, T.A., Sedelnikova, S.E., Partridge, L.J., Blackburn, G.M., Murray, I.A., Kakinuma, H., Takashi, N., Shimazaki, K., Sun, J., Nishi, Y., Rice, D.W. | 2.1 | X-RAY DIFFRACTION | 0.256 | 0.178 | false | true | IGHV1 | IGKV2 | Kappa | 0 | -11.920149 | Unknown | null | TBD |
3j8w | H | L | 0 | E | protein | null | l1 | VIRUS/IMMUNE SYSTEM | 11/19/14 | Cryo-EM reconstruction of quasi-HPV16 complex with H263.A2 Fab | MUS MUSCULUS; HUMAN PAPILLOMAVIRUS TYPE 16 | mus musculus | mus musculus | human papillomavirus type 16 | Guan, J., Hafenstein, S. | 13 | ELECTRON MICROSCOPY | null | null | false | false | IGHV1 | IGKV12 | Kappa | null | null | null | null | null |
7d5p | C | null | 0 | A | protein | null | drug transporter, putative | MEMBRANE PROTEIN | 09/27/20 | Structure of NorC transporter in an outward-open conformation in complex with a single-chain Indian camelid antibody | STAPHYLOCOCCUS AUREUS SUBSP. AUREUS COL; CAMELUS DROMEDARIUS | camelus dromedarius | null | staphylococcus aureus subsp. aureus col | Kumar, S., Athreya, A., Penmatsa, A. | 3.65 | X-RAY DIFFRACTION | 0.318 | 0.297 | false | true | IGHV1 | null | null | null | null | null | null | null |
6dca | I | M | 0 | Q | peptide | null | microtubule-associated protein tau | IMMUNE SYSTEM | 05/04/18 | Fab/epitope complex of mouse monoclonal antibody 6B2 targeting a non-phosphorylated tau epitope. | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | homo sapiens | Chukwu, J.E., Kong, X.-P. | 2.599 | X-RAY DIFFRACTION | 0.259 | 0.189 | false | false | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
7myz | I | M | 0 | D | protein | null | fusion protein of leukocyte surface antigen cd47 an solublecytochrome b562 | MEMBRANE PROTEIN | 05/22/21 | Structure of the full length 5-TM receptor CD47 bound to Fab B6H12 | HOMO SAPIENS; ESCHERICHIA COLI | homo sapiens | homo sapiens | homo sapiens, escherichia coli | Fenalti, G., Villanueva, N. | 3.4 | X-RAY DIFFRACTION | 0.277 | 0.253 | false | true | IGHV5 | IGKV5 | Kappa | null | null | null | null | null |
5hi5 | H | L | 0 | B | protein | null | interleukin-17a | IMMUNE SYSTEM/INHIBITOR | 01/11/16 | Binding site elucidation and structure guided design of macrocyclic IL-17A antagonists | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | homo sapiens | Liu, S. | 1.8 | X-RAY DIFFRACTION | 0.219 | 0.201 | false | true | IGHV3 | IGLV6 | Lambda | null | null | null | null | null |
5mv3 | A | B | 0 | X | peptide | null | synthetic peptide containing the cii583-591 epitope ofcollagen type ii,collagen alpha-1(ii) chain,synthetic peptide containing the cii583-591 epitope of collagen type ii, | IMMUNE SYSTEM | 01/15/17 | ACC1 Fab fragment in complex with CII583-591 (CG10) | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | mus musculus | Dobritzsch, D., Holmdahl, R., Ge, C. | 2.95 | X-RAY DIFFRACTION | 0.261 | 0.202 | false | false | IGHV6 | IGKV3 | Kappa | null | null | null | null | null |
6pef | A | B | 0 | C | peptide | null | hiv fusion peptide residue 512-519 | IMMUNE SYSTEM | 06/20/19 | Vaccine-elicited NHP FP-targeting antibody DF2F-a.01 in complex with HIV fusion peptide (residue 512-519) | MACACA MULATTA; SYNTHETIC CONSTRUCT | macaca mulatta | macaca mulatta | human immunodeficiency virus 1 | Xu, K., Liu, K., Wang, Y., Kwong, P.D. | 2.004 | X-RAY DIFFRACTION | 0.214 | 0.183 | false | true | IGHV4 | IGLV1 | Lambda | null | null | null | null | null |
6ww5 | E | F | 0 | A | protein | null | dass family sodium-coupled anion symporter | MEMBRANE PROTEIN | 05/07/20 | Structure of VcINDY-Na-Fab84 in nanodisc | VIBRIO CHOLERAE; HOMO SAPIENS | homo sapiens | homo sapiens | vibrio cholerae | Sauer, D.B., Marden, J., Song, J.M., Koide, A., Koide, S., Wang, D.N. | 3.15 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6e9h | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 08/01/18 | The crystal structure of bovine ultralong antibody BOV-3 | BOS TAURUS | bos taurus | bos taurus | null | Dong, J., Crowe, J.E. | 2.0 | X-RAY DIFFRACTION | 0.256 | 0.217 | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
5w1m | D | C | 0 | T | protein | null | pre-glycoprotein polyprotein gp complex | VIRAL PROTEIN/IMMUNE SYSTEM | 06/03/17 | MACV GP1 CR1-07 Fab complex | HOMO SAPIENS; MACHUPO VIRUS | homo sapiens | homo sapiens | machupo virus | Raymond, D.D., Clark, L.E., Abraham, J. | 3.91 | X-RAY DIFFRACTION | 0.264 | 0.248 | false | true | IGHV3 | IGKV4 | Kappa | 0 | -10.624477 | SPR | null | TBD |
7tet | M | N | 0 | D | C | protein | protein | NA | NA | glutamate receptor ionotropic, nmda 2b | glutamate receptor ionotropic, nmda 1 | SIGNALING PROTEIN/IMMUNE SYSTEM | 01/05/22 | Cryo-EM structure of GluN1b-2B NMDAR in complex with Fab5 in non-active2-like conformation | RATTUS NORVEGICUS; MUS MUSCULUS | mus musculus | mus musculus | rattus norvegicus | rattus norvegicus | Tajima, N., Furukawa, H. | 4.45 | ELECTRON MICROSCOPY | null | null | false | false | IGHV5 | IGKV3 | Kappa | null | null | null | null | null |
6nf5 | Q | R | 0 | M | protein | null | hiv-1 env bg505 md64 n332-gt5 sosip gp41 | VIRAL PROTEIN/immune system | 12/18/18 | BG505 MD64 N332-GT5 SOSIP trimer in complex with BG18-like precursor HMP1 fragmentantigen binding and base-binding RM20A3 fragment antigen binding | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS; MACACA MULATTA | macaca mulatta | macaca mulatta | human immunodeficiency virus 1 | Ozorowski, G., Torres, J.L., Steichen, J.M., Schief, W.R., Ward, A.B. | 3.71 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGLV2 | Lambda | null | null | null | null | null |
7cu5 | A | a | 0 | Q | protein | null | programmed cell death protein 1 | IMMUNE SYSTEM | 08/21/20 | N-Glycosylation of PD-1 and glycosylation dependent binding of PD-1 specific monoclonal antibody camrelizumab | HOMO SAPIENS | homo sapiens | null | homo sapiens | Liu, K.F., Tan, S.G., Jin, W.J., Guan, J.W., Wang, W.L., Sun, H., Qi, J.X., Yan, J.H., Chai, Y., Wang, Z.F., Chu, X.D., Gao, G.F. | 2.81 | X-RAY DIFFRACTION | 0.252 | 0.212 | true | true | unknown | unknown | unknown | null | null | null | null | null |
4r2g | N | M | 0 | A | protein | null | surface protein gp160 | IMMUNE SYSTEM | 08/11/14 | Crystal Structure of PGT124 Fab bound to HIV-1 JRCSF gp120 core and to CD4 | HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 (JRCSF ISOLATE); HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus type 1 (jrcsfisolate) | Garces, F., Wilson, I.A. | 3.283 | X-RAY DIFFRACTION | 0.263 | 0.207 | false | true | IGHV4 | IGLV3 | Lambda | 0 | -10.188886 | ITC | null | TBD |
6tys | C | D | 0 | B | protein | null | fusion glycoprotein f0 | VIRAL PROTEIN/IMMUNE SYSTEM | 08/09/19 | A potent cross-neutralizing antibody targeting the fusion glycoprotein inhibits Nipah virus and Hendra virus infection | NIPAH VIRUS; MUS MUSCULUS | mus musculus | mus musculus | nipah virus | Dang, H.V., Chan, Y.P., Park, Y.J., Snijder, J., Da Silva, S.C., Vu, B., Yan, L., Feng, Y.R., Rockx, B., Geisbert, T., Mire, C.E., Broder, C.B., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 3.5 | ELECTRON MICROSCOPY | null | null | false | true | IGHV5 | IGKV12 | Kappa | null | null | null | null | null |
6nf2 | N | M | 0 | A | protein | null | envelope glycoprotein gp120 | IMMUNE SYSTEM | 12/18/18 | Cryo-EM structure of vaccine-elicited antibody 0PV-c.01 in complex with HIV-1 Env BG505 DS-SOSIP and antibodies VRC03 and PGT122 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Gorman, J., Kwong, P.D. | 3.7 | ELECTRON MICROSCOPY | null | null | false | true | unknown | IGKV3 | Kappa | null | null | null | null | null |
7ki4 | H | L | 0 | A | protein | null | fusion glycoprotein f0 | VIRAL PROTEIN/IMMUNE SYSTEM | 10/23/20 | Structure of the NiV F glycoprotein in complex with the 12B2 neutralizing antibody | NIPAH VIRUS; MUS MUSCULUS | mus musculus | mus musculus | nipah virus | Dang, H.V., Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D. | 2.9 | ELECTRON MICROSCOPY | null | null | false | true | IGHV2 | IGKV12 | Kappa | null | null | null | null | null |
7lwd | H | L | 0 | A | protein | null | sodium-dependent serotonin transporter | TRANSPORT PROTEIN/Immune System | 03/01/21 | Cryo-EM structure of the wild-type human serotonin transporter complexed with vilazodone, imipramine and 15B8 Fab | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | Yang, D., Kalenderoglou, I.E., Gouaux, E., Coleman, J.A., Loland, C.J. | 3.65 | ELECTRON MICROSCOPY | null | null | false | false | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
4jy6 | D | C | 0 | null | null | null | null | IMMUNE SYSTEM | 03/29/13 | Crystal structure of human Fab PGT123, a broadly reactive and potent HIV-1 neutralizing antibody | HOMO SAPIENS | homo sapiens | homo sapiens | null | Julien, J.-P., Diwanji, D.C., Burton, D.R., Wilson, I.A. | 2.5 | X-RAY DIFFRACTION | 0.265 | 0.207 | false | true | IGHV4 | unknown | unknown | null | null | null | null | null |
3bd5 | null | B | 0 | null | null | null | null | IMMUNE SYSTEM | 11/14/07 | Crystal structure of single domain VL of an anti-DNA binding antibody 3D8 scFv and its active site revealed by complex structures of a small molecule and metals | MUS MUSCULUS | null | mus musculus | null | Park, S.K., Kim, J.S. | 2.0 | X-RAY DIFFRACTION | 0.276 | 0.224 | true | true | null | IGKV8 | Kappa | null | null | null | null | null |
6cm3 | K | J | 0 | D | protein | null | envelope glycoprotein gp160 | VIRAL PROTEIN | 03/02/18 | BG505 SOSIP in complex with sCD4, 17b, 8ANC195 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Wang, H., Bjorkman, P.J. | 3.54 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
7kn7 | H | L | 0 | A | protein | null | spike protein s1 | VIRAL PROTEIN/IMMUNE SYSTEM | 11/04/20 | Crystal structure of SARS-CoV-2 receptor binding domain complexed with nanobody VHH W and antibody Fab CC12.3 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; VICUGNA PACOS; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Liu, H., Yuan, M., Zhu, X., Wu, N.C., Wilson, I.A. | 2.73 | X-RAY DIFFRACTION | 0.241 | 0.203 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
7lf2 | D | E | 0 | A | protein | null | arginase-1 | HYDROLASE/IMMUNE SYSTEM | 01/15/21 | Trimeric human Arginase 1 in complex with mAb4 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Gomez-Llorente, Y., Scapin, G., Palte, R.L. | 3.72 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
3mme | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 04/19/10 | Structure and functional dissection of PG16, an antibody with broad and potent neutralization of HIV-1 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Pancera, M., McLellan, J., Zhou, T., Zhu, J., Kwong, P. | 3.97 | X-RAY DIFFRACTION | 0.317 | 0.256 | false | true | IGHV3 | IGLV2 | Lambda | null | null | null | null | null |
6b0g | D | C | 0 | E | protein | null | 25 kda ookinete surface antigen | IMMUNE SYSTEM | 09/14/17 | Crystal structure of Pfs25 in complex with the transmission blocking antibody 1245 | HOMO SAPIENS; PLASMODIUM FALCIPARUM | homo sapiens | homo sapiens | plasmodium falciparum | McLeod, B., Scally, S.W., Bosch, A., King, C.R., Julien, J.P. | 1.9 | X-RAY DIFFRACTION | 0.200 | 0.164 | false | true | IGHV1 | IGKV2 | Kappa | 0 | -10.243615 | BLI | null | TBD |
5jo5 | C | D | 0 | null | null | null | null | IMMUNE SYSTEM | 05/02/16 | Crystal structure of 10E8 gHV-gLV antigen-binding fragment. | HOMO SAPIENS | homo sapiens | homo sapiens | null | Joyce, M.G., Mascola, J.R., Kwong, P.D. | 1.7 | X-RAY DIFFRACTION | 0.263 | 0.233 | false | true | IGHV3 | IGLV3 | Lambda | null | null | null | null | null |
5lwy | H | L | 0 | A | protein | null | adiponectin receptor protein 2 | MEMBRANE PROTEIN | 09/19/16 | Revised crystal structure of the human adiponectin receptor 2 in complex with a C18 free fatty acid | HOMO SAPIENS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | homo sapiens | Leyrat, C., Vasiliauskaite-Brooks, I., Granier, S. | 2.4 | X-RAY DIFFRACTION | 0.224 | 0.198 | false | true | IGHV1 | IGKV12 | Kappa | null | null | null | null | null |
7t4q | F | G | 0 | C | E | protein | protein | NA | NA | envelope protein ul128 | envelope protein ul131a | VIRAL PROTEIN/Immune System | 12/10/21 | CryoEM structure of the HCMV Pentamer gH/gL/UL128/UL130/UL131A in complex with neutralizing fabs 2C12, 7I13 and 13H11 | HUMAN BETAHERPESVIRUS 5; HOMO SAPIENS | homo sapiens | homo sapiens | human betaherpesvirus 5 | human betaherpesvirus 5 | Kschonsak, M., Johnson, M.C., Schelling, R., Green, E.M., Rouge, L., Ho, H., Patel, N., Kilic, C., Kraft, E., Arthur, C.P., Rohou, A.L., Comps-Agrar, L., Martinez-Martin, N., Perez, L., Payandeh, J., Ciferri, C. | 2.9 | ELECTRON MICROSCOPY | null | null | false | true | IGHV2 | IGLV2 | Lambda | null | null | null | null | null |
5v8l | G | K | 0 | C | protein | null | gp120 | VIRAL PROTEIN/IMMUNE SYSTEM | 03/22/17 | BG505 SOSIP.664 trimer in complex with broadly neutralizing HIV antibodies 3BNC117 and PGT145 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Lee, J.H., Ward, A.B. | 4.3 | ELECTRON MICROSCOPY | null | null | false | true | unknown | IGKV1 | Kappa | null | null | null | null | null |
6plh | B | A | 0 | C | peptide | null | interleukin-21 receptor | IMMUNE SYSTEM | 06/30/19 | FAB fragment complexed with C-mannosylated tryptophan peptide | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | John, A., Jarva, M.A., Goddard-Borger, E.D. | 1.6 | X-RAY DIFFRACTION | 0.221 | 0.189 | false | false | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
6udk | F | I | 0 | K | protein | null | rc1 variant of hiv-1 env glycoprotein gp120 | VIRAL PROTEIN/IMMUNE SYSTEM | 09/19/19 | HIV-1 bNAb 1-55 in complex with modified BG505 SOSIP-based immunogen RC1 and 10-1074 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Abernathy, M.E., Barnes, C.O., Gristick, H.B., Bjorkman, P.J. | 3.9 | ELECTRON MICROSCOPY | null | null | false | true | IGHV4 | unknown | unknown | null | null | null | null | null |
5wko | A | B | 0 | Q | N | protein | protein | NA | NA | hemagglutinin | hemagglutinin | ANTIVIRAL PROTEIN | 07/25/17 | Crystal structure of antibody 27F3 recognizing the HA from A/California/04/2009 (H1N1) influenza virus | HOMO SAPIENS; INFLUENZA A VIRUS | homo sapiens | homo sapiens | influenza a virus | influenza a virus | Wilson, A., Lang, S., Zhu, X. | 3.492 | X-RAY DIFFRACTION | 0.268 | 0.246 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
4lvh | E | F | 0 | D | protein | null | hemagglutinin | IMMUNE SYSTEM | 07/26/13 | Insight into highly conserved H1 subtype-specific epitopes in influenza virus hemagglutinin | INFLUENZA A VIRUS; MUS MUSCULUS | mus musculus | mus musculus | influenza a virus | Kim, K.H., Cho, K.J., Kim, S., Seok, J.H., Lee, J.-H. | 2.8 | X-RAY DIFFRACTION | 0.274 | 0.232 | false | false | IGHV5 | IGKV3 | Kappa | null | null | null | null | null |
6bpc | E | F | 0 | D | protein | null | reticulocyte binding protein 2, putative | CELL INVASION | 11/22/17 | Plasmodium vivax reticulocyte binding protein 2b (PvRBP2b) bound to monoclonal antibody 4F7 | PLASMODIUM VIVAX (STRAIN SALVADOR I); MUS MUSCULUS | mus musculus | mus musculus | plasmodium vivax (strain salvador i) | Gruszczyk, J., Chan, L.J., Tham, W.H. | 2.66 | X-RAY DIFFRACTION | 0.215 | 0.197 | false | false | IGHV5 | IGKV6 | Kappa | null | null | null | null | null |
6fy2 | H | L | 0 | P | peptide | null | cap225 scaffolded v1v2 | IMMUNE SYSTEM | 03/10/18 | Crystal structure of a V2p-reactive RV144 vaccine-like antibody, CAP228-16H, in complex with a heterologous CAP225 V1V2 | HOMO SAPIENS; HUMAN IMMUNODEFICIENCY VIRUS 1 | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Wibmer, C.K., Moore, P.L., Morris, L. | 2.301 | X-RAY DIFFRACTION | 0.217 | 0.190 | false | true | IGHV5 | IGLV3 | Lambda | null | null | null | null | null |
6by2 | A | B | 0 | C | protein | null | ph-gated potassium channel kcsa | MEMBRANE PROTEIN | 12/19/17 | Closed and deep-inactivated conformation of KcsA-T75A mutant | MUS MUSCULUS; STREPTOMYCES COELICOLOR | mus musculus | mus musculus | streptomyces coelicolor | Labro, A.J., Cortes, D.M., Tilegenova, C., Cuello, L.G. | 2.35 | X-RAY DIFFRACTION | 0.245 | 0.221 | false | true | IGHV1 | IGKV5 | Kappa | null | null | null | null | null |
5hcg | H | null | 0 | null | null | null | null | IMMUNE SYSTEM | 01/04/16 | CRYSTAL STRUCTURE OF FREE-CODV. | HOMO SAPIENS | homo sapiens | null | null | Vallee, F., Dupuy, A., Rak, A. | 2.68 | X-RAY DIFFRACTION | 0.297 | 0.229 | false | true | IGHV2 | null | null | null | null | null | null | null |
3eyf | D | C | 0 | F | peptide | null | synthetic peptide | IMMUNE SYSTEM | 10/20/08 | Crystal structure of anti-human cytomegalovirus antibody 8f9 plus gB peptide | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | null | Thomson, C.A., Bryson, S., McLean, G.R., Creagh, A.L., Pai, E.F., Schrader, J.W. | 2.3 | X-RAY DIFFRACTION | 0.230 | 0.210 | false | true | IGHV3 | IGKV3 | Kappa | 0 | -9.3 | ITC | 24 | 18772881 |
6k2i | A | null | 10 | null | null | null | null | AFB1-BINDING PROTEIN | 05/14/19 | Solution structure of camelid nanobody Nb11 against aflatoxin B1 | VICUGNA PACOS | vicugna pacos | null | null | Nie, Y., Li, S.L., He, T., Zhu, J., Yang, Y.H. | NOT | SOLUTION NMR | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
6fgb | H | L | 0 | A | B | protein | protein | NA | NA | igg receptor fcrn large subunit p51 | beta-2-microglobulin | IMMUNE SYSTEM | 01/10/18 | Human FcRn extra-cellular domain complexed with Fab fragment of Rozanolixizumab | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | homo sapiens | Sarkar, K., Ceska, T., Meier, C. | 2.9 | X-RAY DIFFRACTION | 0.284 | 0.232 | false | true | IGHV3 | IGKV1 | Kappa | 0 | -13.955055 | SPR | null | TBD |
6n35 | M | K | 0 | M | carbohydrate | MAN | ALPHA-D-MANNOSE | IMMUNE SYSTEM | 11/14/18 | Anti-HIV-1 Fab 2G12 + Man1-2 re-refinement | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Calarese, D.A., Stanfield, R.L., Wilson, I.A. | 1.747 | X-RAY DIFFRACTION | 0.238 | 0.207 | false | true | unknown | IGKV1 | Kappa | null | null | null | null | null |
7x8s | N | null | 0 | A | B | protein | protein | NA | NA | guanine nucleotide-binding protein g(s) subunit alphaisoforms short | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | MEMBRANE PROTEIN | 03/14/22 | Cryo-EM structure of the WB4-24-bound hGLP-1R-Gs complex | Bos taurus; Homo sapiens; Rattus norvegicus; synthetic construct | synthetic construct | null | bos taurus | rattus norvegicus | Cong, Z.T., Zhou, Q.T., Li, Y., Chen, L.N., Zhang, Z.C., Liang, A.Y., Liu, Q., Wu, X.Y., Dai, A.T., Xia, T., Wu, W., Zhang, Y., Yang, D.H., Wang, M.W. | 3.09 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | null | null | null | null | null | null | null |
7vyt | B | C | 0 | A | protein | null | t-cell immunoreceptor with ig and itim domains | IMMUNE SYSTEM | 11/15/21 | Crystal structure of human TIGIT(23-129) in complex with the scFv fragment of anti-TIGIT antibody MG1131 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Jeong, B.-S., Nam, H., Kim, M., Oh, B.-H. | 1.53 | X-RAY DIFFRACTION | 0.219 | 0.201 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
7rm1 | C | D | 0 | P | peptide | null | peptide from circumsporozoite protein variant vk247 | ANTIMICROBIAL PROTEIN | 07/26/21 | Antibody 2F2 in complex with P. vivax CSP peptide EDGAGNQPGANGAGNQPGANGAGNQPG | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | plasmodium vivax | Kucharska, I., Ivanochko, D., Julien, J.P. | 3.19 | X-RAY DIFFRACTION | 0.210 | 0.180 | false | true | IGHV9 | IGKV8 | Kappa | null | null | null | null | null |
3ghe | H | L | 0 | P | peptide | null | envelope glycoprotein | IMMUNE SYSTEM | 03/03/09 | Crystal structure of anti-HIV-1 Fab 537-10D in complex with V3 peptide MN | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | null | Kong, X.P., Burke, V.J. | 2.4 | X-RAY DIFFRACTION | 0.241 | 0.187 | false | false | IGHV3 | IGLV2 | Lambda | 0.000001 | -8.03 | Other | 25 | 19913488 |
7d3r | H | L | 0 | 1 | 3 | protein | protein | NA | NA | a/wh/cha/09 vp1 | a/wh/cha/09 vp3 | VIRUS | 09/20/20 | FOOT AND MOUTH DISEASE VIRUS A/WH/CHA/09-BOUND THE SINGLE CHAIN FRAGME ANTIBODY R50 | BOS TAURUS; FOOT-AND-MOUTH DISEASE VIRUS | bos taurus | bos taurus | foot-and-mouth disease virus | foot-and-mouth disease virus | He, Y., Lou, Z. | 3.49 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
6bpd | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 11/22/17 | Plasmodium vivax invasion blocking monoclonal antibody 10B12 | MUS MUSCULUS | mus musculus | mus musculus | null | Gruszczyk, J., Chan, L.J., Tham, W.H. | 2.32 | X-RAY DIFFRACTION | 0.262 | 0.211 | false | false | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
5czv | H | L | 0 | A | protein | null | neurogenic locus notch homolog protein 3 | IMMUNE SYSTEM | 08/01/15 | Crystal structure of Notch3 NRR in complex with 20350 Fab | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Hu, T., Fryer, C., Chopra, R., Clark, K. | 3.19 | X-RAY DIFFRACTION | 0.257 | 0.204 | false | true | IGHV1 | IGKV1 | Kappa | 0 | -12.991531 | SPR | null | TBD |
4kk6 | C | D | 0 | A | protein | null | h(+)/cl(-) exchange transporter clca | TRANSPORT PROTEIN | 05/05/13 | Structure of CLC-ec1 deltaNC construct in 20mM Bromide | ESCHERICHIA COLI; MUS MUSCULUS | mus musculus | mus musculus | escherichia coli | Lim, H.-H., Miller, C. | 3.183 | X-RAY DIFFRACTION | 0.269 | 0.235 | false | true | IGHV4 | IGKV4 | Kappa | null | null | null | null | null |
6tkd | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 11/28/19 | ChiLob 7/4 H2 HC-C228S F(ab')2 | HOMO SAPIENS | null | null | null | Orr, C.M., Fisher, H., Tews, I. | 1.9 | X-RAY DIFFRACTION | 0.206 | 0.173 | false | false | IGHV1 | IGKV10 | Kappa | null | null | null | null | null |
4llv | E | F | 0 | null | null | null | null | IMMUNE SYSTEM | 07/09/13 | The structure of the unbound form of anti-HIV antibody 4E10 Fv | HOMO SAPIENS | homo sapiens | homo sapiens | null | Finton, K.A.K., Rupert, P.B., Strong, R.K. | 2.39 | X-RAY DIFFRACTION | 0.245 | 0.216 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
2vyr | H | null | 0 | D | protein | null | mdm4 protein | IMMUNE SYSTEM | 07/28/08 | Structure of human MDM4 N-terminal domain bound to a single domain antibody | HOMO SAPIENS | homo sapiens | null | homo sapiens | Yu, G.W., Vaysburd, M., Allen, M.D., Settanni, G., Fersht, A.R. | 2.0 | X-RAY DIFFRACTION | 0.248 | 0.207 | false | true | IGHV3 | null | null | 0 | -9.69 | ITC | 15 | 19084022 |
1emt | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 03/17/00 | FAB ANTIBODY FRAGMENT OF AN C60 ANTIFULLERENE ANTIBODY | MUS MUSCULUS | mus musculus | mus musculus | null | Braden, B.C., Goldbaum, F.A., Chen, B.-X., Erlanger, B.F., Kirschner, A.N., Wilson, S.R. | 2.25 | X-RAY DIFFRACTION | 0.240 | 0.180 | false | false | IGHV1 | IGKV10 | Kappa | null | null | null | null | null |
6ye3 | A | B | 0 | C | protein | null | interleukin-2 | PROTEIN BINDING | 03/23/20 | IL-2 in complex with a Fab fragment from UFKA-20 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Karakus, U., Mittl, P., Boyman, O. | 2.89 | X-RAY DIFFRACTION | 0.283 | 0.215 | false | true | IGHV5 | IGKV8 | Kappa | null | null | null | null | null |
4jfz | H | L | 0 | P | peptide | null | phosphopeptide | immune system | 02/28/13 | Structure of phosphoserine (pSAb) scaffold bound to pSer peptide | ESCHERICHIA COLI; SYNTHETIC CONSTRUCT | null | null | null | Koerber, J.T., Thomsen, N.D., Hannigan, B.T., Degrado, W.F., Wells, J.A. | 1.75 | X-RAY DIFFRACTION | 0.199 | 0.154 | false | true | IGHV3 | IGKV3 | Kappa | 0 | -9.752629 | Unknown | null | TBD |
2qr0 | T | S | 0 | U | protein | null | vascular endothelial growth factor a | IMMUNE SYSTEM | 07/27/07 | Structure of VEGF complexed to a Fab containing TYR and SER in the CDRs | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Wiesmann, C. | 3.5 | X-RAY DIFFRACTION | 0.312 | 0.291 | false | false | IGHV3 | IGKV1 | Kappa | 0 | -11.5 | SPR | 37 | 17825836 |
4aiz | null | B | 0 | null | null | null | null | IMMUNE SYSTEM | 02/15/12 | Crystallographic structure of 3mJL2 from the germinal line lambda 3 | HOMO SAPIENS | null | homo sapiens | null | Villalba, M.I., Luna, O.D., Rudino-Pinera, E., Sanchez, R., Sanchez-Lopez, R., Rojas-Trejo, S., Olamendi-Portugal, T., Fernandez-Velasco, D.A., Becerril, B. | 1.75 | X-RAY DIFFRACTION | 0.2185 | 0.1662 | false | true | null | IGLV3 | Lambda | null | null | null | null | null |
6cde | Q | R | 0 | C | protein | null | glycoprotein 120 | VIRAL PROTEIN | 02/08/18 | Cryo-EM structure at 3.8 A resolution of vaccine-elicited antibody vFP20.01 in complex with HIV-1 Env BG505 DS-SOSIP, and antibodies VRC03 and PGT122 | HOMO SAPIENS; HUMAN IMMUNODEFICIENCY VIRUS 1 | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Acharya, P., Xu, K., Liu, K., Carragher, B., Potter, C.S., Kwong, P.D. | 3.8 | ELECTRON MICROSCOPY | null | null | false | true | unknown | IGKV3 | Kappa | null | null | null | null | null |
7cwn | G | F | 0 | A | protein | null | spike glycoprotein | VIRAL PROTEIN | 08/29/20 | P17-H014 Fab cocktail in complex with SARS-CoV-2 spike protein | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Wang, N., Wang, X. | 3.2 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6zwk | E | null | 0 | K | peptide | null | histone h2ax | IMMUNE SYSTEM | 07/28/20 | Crystal structure of the phosphorylated C-terminal tail of histone H2AX in complex with a specific nanobody (C6 gammaXbody) | VICUGNA PACOS; SYNTHETIC CONSTRUCT | vicugna pacos | null | homo sapiens | McEwen, A.G., Moeglin, E., Desplancq, D., Weiss, E., Poterszman, A. | 1.55 | X-RAY DIFFRACTION | 0.184 | 0.149 | false | true | IGHV1 | null | null | null | null | null | null | null |
7mxl | H | L | 0 | C | protein | null | major pollen allergen bet v 1-a | ALLERGEN | 05/19/21 | Complex of Bet v 1 with the Fab fragments of a three antibody cocktail | HOMO SAPIENS; BETULA PENDULA | homo sapiens | homo sapiens | betula pendula | Romero-Hernandez, A., Franklin, M.C. | 3.2 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
5lsp | S | T | 0 | P | protein | null | hepatocyte growth factor receptor | TRANSFERASE | 09/05/16 | 107_A07 Fab in complex with fragment of the Met receptor | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | DiCara, D., Chirgadze, D.Y., Pope, A., Karatt-Vellatt, A., Winter, A., van den Heuvel, J., Gherardi, E., McCafferty, J. | 2.605 | X-RAY DIFFRACTION | 0.257 | 0.215 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
7vyr | A | B | 0 | C | protein | null | spike protein s1 | VIRAL PROTEIN/IMMUNE SYSTEM | 11/15/21 | Crystal structure of SARS-CoV-2 Spike RBD in complex with the D27 neutralizing antibody Fab fragment | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Jeong, B.-S., Oh, B.-H. | 2.2 | X-RAY DIFFRACTION | 0.235 | 0.192 | false | true | IGHV1 | IGLV3 | Lambda | null | null | null | null | null |
4r7d | O | P | 0 | null | null | null | null | IMMUNE SYSTEM | 08/27/14 | Fab Hu 15C1 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Loyau, J., Didelot, G., Malinge, P., Ravn, U., Magistrelli, G., Depoisier, J.F., Kosco-Vilbois, M., Fischer, N., Thore, S., Rousseau, F. | 2.753 | X-RAY DIFFRACTION | 0.209 | 0.177 | false | true | IGHV4 | IGKV6 | Kappa | null | null | null | null | null |
4ydi | H | L | 0 | G | protein | null | envelope glycoprotein gp160 | IMMUNE SYSTEM | 02/22/15 | Crystal structure of broad and potently neutralizing VRC01-class antibody Z258-VRC27.01, isolated from human donor Z258, in complex with HIV-1 gp120 from clade A strain Q23.17 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Zhou, T., Srivatsan, S., Kwong, P.D. | 3.452 | X-RAY DIFFRACTION | 0.276 | 0.222 | false | true | unknown | unknown | unknown | null | null | null | null | null |
6u3z | C | D | 0 | null | null | null | null | IMMUNE SYSTEM | 08/22/19 | Structure of VD20_5A4 Fab | MACACA MULATTA | macaca mulatta | macaca mulatta | null | Dionne, G., Shapiro, L. | 1.99002 | X-RAY DIFFRACTION | 0.236 | 0.199 | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
5j74 | B | b | 0 | b | Hapten | 6GN | 1-(17-amino-5,8-dioxo-12,15-dioxa-4,9-diazaheptadecan-1-yl)-4-{[3-(3-sulfopropyl)-1,3-benzothiazol-3-ium-2-yl]methyl}quinolin-1-ium | IMMUNE SYSTEM | 04/05/16 | Fluorogen activating protein AM2.2 in complex with TO1-2p | HOMO SAPIENS | homo sapiens | null | null | Stanfield, R.L., Wilson, I.A., Wu, Y. | 2.7 | X-RAY DIFFRACTION | 0.250 | 0.197 | true | true | unknown | unknown | unknown | 0 | -11.897909 | Unknown | null | TBD |
5utf | D | E | 0 | B | protein | null | envelope glycoprotein gp41 | IMMUNE SYSTEM | 02/14/17 | Crystal Structure of a Stabilized DS-SOSIP.6mut BG505 gp140 HIV-1 Env Trimer, Containing Mutations I201C-P433C (DS), L154M, Y177W, N300M, N302M, T320L, I420M in Complex with Human Antibodies PGT122 and 35O22 at 4.3 A | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Pancera, M., Chuang, G.-Y., Xu, K., Kwong, P.D. | 3.503 | X-RAY DIFFRACTION | 0.299 | 0.216 | false | true | unknown | unknown | unknown | null | null | null | null | null |
6iyn | A | null | 15 | null | null | null | null | AFLATOXIN B1-BINDING PROTEIN | 12/17/18 | Solution structure of camelid nanobody Nb26 against aflatoxin B1 | VICUGNA PACOS | vicugna pacos | null | null | Nie, Y., He, T., Zhu, J., Li, S.L., Hu, R., Yang, Y.H. | NOT | SOLUTION NMR | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
3w11 | C | D | 0 | E | protein | null | insulin receptor domains l1-cr | HORMONE/HORMONE RECEPTOR/IMMUNE SYSTEM | 11/06/12 | Insulin receptor ectodomain construct comprising domains L1-CR in complex with human insulin, Alpha-CT peptide(704-719) and FAB 83-7 | HOMO SAPIENS; MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | homo sapiens | Lawrence, M.C., Smith, B.J. | 3.9 | X-RAY DIFFRACTION | 0.292 | 0.264 | false | true | IGHV2 | IGKV8 | Kappa | null | null | null | null | null |
4nki | H | L | 0 | null | null | null | null | CYTOKINE | 11/12/13 | Crystal structure of a Fab | HOMO SAPIENS | homo sapiens | homo sapiens | null | Jiang, X. | 2.41 | X-RAY DIFFRACTION | 0.245 | 0.197 | false | true | IGHV3 | IGLV2 | Lambda | null | null | null | null | null |
6do1 | C | null | 0 | A | protein | null | type-1 angiotensin ii receptor,soluble cytochrome b562 brilfusion protein | MEMBRANE PROTEIN | 06/08/18 | Structure of nanobody-stabilized angiotensin II type 1 receptor bound to S1I8 | HOMO SAPIENS; ESCHERICHIA COLI; SYNTHETIC CONSTRUCT | synthetic construct | null | homo sapiens, escherichia coli | Wingler, L.M., McMahon, C., Staus, D.P., Lefkowitz, R.J., Kruse, A.C. | 2.901 | X-RAY DIFFRACTION | 0.359 | 0.305 | false | true | IGHV1 | null | null | null | null | null | null | null |
7ki6 | D | C | 0 | B | protein | null | fusion glycoprotein f0 | VIRAL PROTEIN/IMMUNE SYSTEM | 10/23/20 | Structure of the HeV F glycoprotein in complex with the 1F5 neutralizing antibody | HENDRA HENIPAVIRUS; MUS MUSCULUS | mus musculus | mus musculus | hendra henipavirus | Dang, H.V., Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D. | 2.8 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV4 | Kappa | null | null | null | null | null |
6cnk | K | J | 0 | E | D | protein | protein | NA | NA | neuronal acetylcholine receptor subunit beta-2 | neuronal acetylcholine receptor subunit alpha-4 | TRANSPORT PROTEIN | 03/08/18 | Structure of the 3alpha2beta stiochiometry of the human Alpha4Beta2 nicotinic receptor | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | homo sapiens | Walsh Jr, R.M., Roh, S.H., Gharpure, A., Morales-Perez, C.L., Hibbs, R.E. | 3.7 | ELECTRON MICROSCOPY | null | null | false | false | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
5mub | O | P | 0 | Q | peptide | null | triple-helical peptide containing the citrullinated c1epitope of collagen type ii,collagen alpha-1(ii) chain,triple-helical peptide containing the citrullinated c1 epitope of collagen type ii | IMMUNE SYSTEM | 01/13/17 | ACC1 Fab fragment in complex with citrullinated C1 epitope of CII (CG05) | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | mus musculus | Dobritzsch, D., Holmdahl, R., Ge, C. | 3.1 | X-RAY DIFFRACTION | 0.264 | 0.231 | false | false | IGHV6 | IGKV3 | Kappa | null | null | null | null | null |
5vnw | C | null | 0 | B | protein | null | serum albumin | TRANSPORT PROTEIN/DE NOVO PROTEIN | 05/01/17 | Crystal structure of Nb.b201 bound to human serum albumin | HOMO SAPIENS; SYNTHETIC CONSTRUCT | synthetic construct | null | homo sapiens | McMahon, C., Kruse, A.C. | 2.6 | X-RAY DIFFRACTION | 0.256 | 0.221 | false | true | IGHV1 | null | null | null | null | null | null | null |
6mee | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 09/06/18 | Broadly neutralizing antibodies against HCV use a CDRH3 disulfide motif to recognize an E2 glycoprotein site that can be targeted for vaccine design | HOMO SAPIENS | homo sapiens | homo sapiens | null | Flyak, A.I., Bjorkman, P.J. | 1.36 | X-RAY DIFFRACTION | 0.191 | 0.167 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
4gxu | Q | R | 0 | E | protein | null | hemagglutinin ha1 chain | VIRAL PROTEIN/IMMUNE SYSTEM | 09/04/12 | Crystal structure of antibody 1F1 bound to the 1918 influenza hemagglutinin | HOMO SAPIENS; INFLUENZA A VIRUS | homo sapiens | homo sapiens | influenza a virus | Ekiert, D.C., Wilson, I.A. | 3.294 | X-RAY DIFFRACTION | 0.255 | 0.219 | false | true | IGHV3 | IGLV1 | Lambda | 0 | null | SPR | null | 23236279 |
5mub | U | V | 0 | W | peptide | null | triple-helical peptide containing the citrullinated c1epitope of collagen type ii,collagen alpha-1(ii) chain,triple-helical peptide containing the citrullinated c1 epitope of collagen type ii | IMMUNE SYSTEM | 01/13/17 | ACC1 Fab fragment in complex with citrullinated C1 epitope of CII (CG05) | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | mus musculus | Dobritzsch, D., Holmdahl, R., Ge, C. | 3.1 | X-RAY DIFFRACTION | 0.264 | 0.231 | false | false | IGHV6 | IGKV3 | Kappa | null | null | null | null | null |
7l5j | W | L | 0 | B | protein | null | capsid protein | VIRAL PROTEIN/IMMUNE SYSTEM | 12/22/20 | Mouse Norovirus Protruding domain complexed with neutralizing Fab fragment from mAb A6.2 | MURINE NOROVIRUS 1; MUS MUSCULUS | mus musculus | mus musculus | murine norovirus 1 | Smith, T.J., Sherman, M.B. | 3.2 | ELECTRON MICROSCOPY | null | null | false | false | IGHV4 | IGKV4 | Kappa | null | null | null | null | null |
3h3p | H | L | 0 | S | peptide | null | 4e10_s0_1tjlc_004_n | IMMUNE SYSTEM | 04/16/09 | Crystal structure of HIV epitope-scaffold 4E10 Fv complex | HOMO SAPIENS; ARTIFICIAL GENE | homo sapiens | homo sapiens | artificial gene | Holmes, M.A. | 2.7 | X-RAY DIFFRACTION | 0.287 | 0.229 | false | true | IGHV1 | IGKV3 | Kappa | 0 | -10.71 | SPR | 25 | 19906921 |
7f0t | E | null | 0 | A | B | D | protein | protein | protein | NA | NA | NA | guanine nucleotide-binding protein g(s) subunit alphaisoforms short,isoform gnas-2 of guanine nucleotide-binding protein g(s) subunit alpha isoforms short | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | guanine nucleotide-binding protein g(i)/g(s)/g(o) subunitgamma-2 | MEMBRANE PROTEIN | 06/07/21 | Cryo-EM structure of dopamine receptor 1 and mini-Gs complex with dopamine bound | HOMO SAPIENS; SYNTHETIC CONSTRUCT | synthetic construct | null | homo sapiens | homo sapiens | homo sapiens | Xiao, T., Zheng, S. | 3.1 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | null | null | null | null | null | null | null |
4nm8 | J | N | 0 | F | E | protein | protein | NA | NA | hemagglutinin ha2 chain | hemagglutinin ha1 chain | viral protein/immune system | 11/14/13 | Crystal structure of broadly neutralizing antibody CR8043 bound to H3 influenza hemagglutinin | INFLUENZA A VIRUS; HOMO SAPIENS | homo sapiens | homo sapiens | influenza a virus | influenza a virus | Lee, P.S., Wilson, I.A. | 4.0041 | X-RAY DIFFRACTION | 0.292 | 0.240 | false | true | IGHV1 | IGKV4 | Kappa | 0 | -11.735309 | BLI | null | TBD |
1z3g | H | L | 0 | A | protein | null | ookinete surface protein pvs25 | IMMUNE SYSTEM/CELL ADHESION | 03/12/05 | Crystal structure of complex between Pvs25 and Fab fragment of malaria transmission blocking antibody 2A8 | MUS MUSCULUS; PLASMODIUM VIVAX SAI-1 | mus musculus | mus musculus | plasmodium vivax sai-1 | Saxena, A.K., Singh, K., Su, H.P., Klein, M.M., Stowers, A.W., Saul, A.J., Long, C.A., Garboczi, D.N. | 3.3 | X-RAY DIFFRACTION | 0.327 | 0.272 | false | true | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
1nqb | A | a | 0 | null | null | null | null | IMMUNOGLOBULIN | 04/04/97 | TRIVALENT ANTIBODY FRAGMENT | MUS MUSCULUS | mus musculus | null | null | Williams, R.L., Pei, X.Y. | 2.0 | X-RAY DIFFRACTION | 0.230 | 0.187 | true | true | unknown | unknown | unknown | null | null | null | null | null |
3ghb | H | L | 0 | P | peptide | null | envelope glycoprotein | IMMUNE SYSTEM | 03/03/09 | Crystal structure of anti-HIV-1 Fab 447-52D in complex with V3 peptide W2RW020 | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | null | Kong, X.P., Burke, V.J. | 2.25 | X-RAY DIFFRACTION | 0.232 | 0.196 | false | false | IGHV3 | IGLV1 | Lambda | null | null | null | null | null |
2r0w | H | L | 0 | Q | peptide | null | amyloid beta peptide fragment | IMMUNE SYSTEM | 08/21/07 | PFA2 FAB complexed with Abeta1-8 | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | null | Gardberg, A.S., Dealwis, C. | 2.503 | X-RAY DIFFRACTION | 0.277 | 0.208 | false | false | IGHV8 | IGKV1 | Kappa | null | null | null | null | null |
1kxv | D | null | 0 | B | protein | null | alpha-amylase, pancreatic | HYDROLASE, IMMUNE SYSTEM | 02/01/02 | Camelid VHH Domains in Complex with Porcine Pancreatic alpha-Amylase | CAMELUS DROMEDARIUS; SUS SCROFA | camelus dromedarius | null | sus scrofa | Desmyter, A., Spinelli, S., Payan, F., Lauwereys, M., Wyns, L., Muyldermans, S., Cambillau, C. | 1.6 | X-RAY DIFFRACTION | 0.229 | 0.205 | false | true | IGHV1 | null | null | 0 | -10.37 | SPR | null | 11960990 |
6sxi | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 09/26/19 | Antibody-anti-idiotype complex: AP33 Fab (hepatitis C virus E2 antibody) - B2.1A scFv (anti-idiotype) | MUS MUSCULUS | mus musculus | mus musculus | null | Taylor, G.L., Potter, J.A., Fadda, V., Patel, A.H., Owsianka, A.M., Cowtan, V.M. | 1.85 | X-RAY DIFFRACTION | 0.203 | 0.156 | false | false | IGHV1 | IGKV6 | Kappa | null | null | null | null | null |
7rks | H | L | 0 | R | protein | null | spike protein s1 | VIRAL PROTEIN/IMMUNE SYSTEM | 07/22/21 | Structure of the SARS-CoV-2 receptor binding domain in complex with the human neutralizing antibody Fab fragment, C118 | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus | Jette, C.A., Bjorkman, P.J., Barnes, C.O. | 2.7 | X-RAY DIFFRACTION | 0.247 | 0.195 | false | true | IGHV3 | IGLV4 | Lambda | null | null | null | null | null |
1a4j | H | L | 0 | null | null | null | null | IMMUNOGLOBULIN | 01/30/98 | DIELS ALDER CATALYTIC ANTIBODY GERMLINE PRECURSOR | MUS MUSCULUS | mus musculus | mus musculus | null | Spiller, B.W., Romesburg, F.E., Schultz, P.G., Stevens, R.C. | 2.1 | X-RAY DIFFRACTION | 0.292 | 0.229 | false | true | IGHV9 | IGKV1 | Kappa | null | null | null | null | null |
3o6m | H | L | 0 | C | peptide | null | protein tat 9-mer peptide | IMMUNE SYSTEM | 07/29/10 | Anti-Tat HIV 11H6H1 Fab' complexed with a 9-mer Tat peptide | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | null | Serriere, J., Gouet, P., Guillon, C. | 2.4 | X-RAY DIFFRACTION | 0.290 | 0.211 | false | false | IGHV5 | IGKV1 | Kappa | 0 | -9.89 | Other | 16 | 21035463 |
6b20 | F | null | 0 | A | protein | null | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | SIGNALING PROTEIN | 09/19/17 | Crystal structure of a complex between G protein beta gamma dimer and an inhibitory Nanobody regulator | BOS TAURUS; LAMA GLAMA | lama glama | null | bos taurus | Gulati, S., Kiser, P.D., Palczewski, K. | 2.34 | X-RAY DIFFRACTION | 0.249 | 0.200 | false | true | IGHV1 | null | null | null | null | null | null | null |
1dqj | B | A | 0 | C | protein | null | lysozyme | immune system/hydrolase | 01/04/00 | CRYSTAL STRUCTURE OF THE ANTI-LYSOZYME ANTIBODY HYHEL-63 COMPLEXED WITH HEN EGG WHITE LYSOZYME | MUS MUSCULUS; GALLUS GALLUS | mus musculus | mus musculus | gallus gallus | Li, H., Mariuzza, R.A. | 2.0 | X-RAY DIFFRACTION | 0.250 | 0.217 | false | true | IGHV3 | IGKV5 | Kappa | 0 | -11.45 | SPR | 25 | 10828942 |
7vuy | S | s | 0 | A | B | protein | protein | NA | NA | guanine nucleotide-binding protein g(i) subunit alpha-1 | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | MEMBRANE PROTEIN | 11/04/21 | Cryo-EM structure of pseudoallergen receptor MRGPRX2 complex with PAMP-12. state1 | HOMO SAPIENS | homo sapiens | null | homo sapiens | homo sapiens | Yu, L., Fang, Y. | 2.84 | ELECTRON MICROSCOPY | null | null | true | true | unknown | unknown | unknown | null | null | null | null | null |
4gxu | O | P | 0 | C | protein | null | hemagglutinin ha1 chain | VIRAL PROTEIN/IMMUNE SYSTEM | 09/04/12 | Crystal structure of antibody 1F1 bound to the 1918 influenza hemagglutinin | HOMO SAPIENS; INFLUENZA A VIRUS | homo sapiens | homo sapiens | influenza a virus | Ekiert, D.C., Wilson, I.A. | 3.294 | X-RAY DIFFRACTION | 0.255 | 0.219 | false | true | IGHV3 | IGLV1 | Lambda | 0 | null | SPR | null | 23236279 |
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