pdb stringlengths 4 4 | Hchain stringclasses 59
values | Lchain stringclasses 60
values | model int64 0 76 | antigen_chain stringclasses 386
values | antigen_type stringclasses 24
values | antigen_het_name stringclasses 240
values | antigen_name stringlengths 1 396 ⌀ | short_header stringclasses 448
values | date stringlengths 8 8 | compound stringlengths 4 243 | organism stringlengths 3 175 ⌀ | heavy_species stringclasses 121
values | light_species stringclasses 67
values | antigen_species stringclasses 937
values | authors stringlengths 6 762 | resolution stringlengths 1 8 | method stringclasses 10
values | r_free stringclasses 354
values | r_factor stringclasses 342
values | scfv bool 2
classes | engineered bool 2
classes | heavy_subclass stringclasses 14
values | light_subclass stringclasses 35
values | light_ctype stringclasses 3
values | affinity float64 0 0 ⌀ | delta_g float64 -16.91 -5.04 ⌀ | affinity_method stringclasses 11
values | temperature float64 4 37 ⌀ | pmid stringclasses 157
values |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
7t6u | E | e | 0 | A | B | protein | protein | NA | NA | guanine nucleotide-binding protein g(i) subunit alpha-1 | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | SIGNALING PROTEIN | 12/14/21 | Molecular recognition of formylpeptides and diverse agonists by the formylpeptide receptors FPR1 and FPR2 | HOMO SAPIENS; RATTUS; BOS TAURUS; SYNTHETIC CONSTRUCT | rattus | null | homo sapiens | rattus | Zhuang, Y.W. | 2.9 | ELECTRON MICROSCOPY | null | null | true | true | unknown | unknown | unknown | null | null | null | null | null |
7na9 | D | null | 0 | A | protein | null | botulinum neurotoxin type b | TOXIN | 06/20/21 | Crystal structure of BoNT/B-LC-JSG-C1 | CLOSTRIDIUM BOTULINUM; VICUGNA PACOS | vicugna pacos | null | clostridium botulinum | Lam, K., Jin, R. | 1.76 | X-RAY DIFFRACTION | 0.205 | 0.167 | false | true | IGHV1 | null | null | null | null | null | null | null |
2dqt | H | L | 0 | H | Hapten | CPD | [1-(3-DIMETHYLAMINO-PROPYL)-3-ETHYL-UREIDO]-[4-(2,2,2-TRIFLUORO-ACETYLAMINO)-BENZYL]PHOSPHINIC ACID-2-(2,2-DIHYDRO-ACETYLAMINO)-3-HYDROXY-1-(4-NITROPHENYL)-PROPYL ESTER | IMMUNE SYSTEM | 05/30/06 | High resolution crystal structure of the complex of the hydrolytic antibody Fab 6D9 and a transition-state analog | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Kristensen, O., Vassylyev, D.G., Tanaka, F., Ito, N., Morikawa, K., Fujii, I. | 1.8 | X-RAY DIFFRACTION | 0.246 | 0.187 | false | false | IGHV5 | IGKV1 | Kappa | null | null | null | null | null |
7lfb | H | L | 0 | X | protein | null | apolipoprotein l1 | IMMUNE SYSTEM | 01/16/21 | Fab 7D6 bound to ApoL1 NTD | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Ultsch, M., Kirchhofer, D. | 1.913 | X-RAY DIFFRACTION | 0.197 | 0.168 | false | true | IGHV9 | IGKV12 | Kappa | null | null | null | null | null |
4g6f | B | D | 0 | F | peptide | null | gp41 mper peptide | IMMUNE SYSTEM | 07/19/12 | Crystal Structure of 10E8 Fab in Complex with an HIV-1 gp41 Peptide | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Ofek, G., Huang, J., Connors, M., Kwong, P.D. | 2.1 | X-RAY DIFFRACTION | 0.218 | 0.180 | false | true | IGHV3 | IGLV3 | Lambda | 0 | -10.599564 | Unknown | null | TBD |
4ut6 | H | L | 0 | A | protein | null | envelope glycoprotein e | VIRAL PROTEIN | 07/18/14 | Crystal structure of dengue 2 virus envelope glycoprotein in complex with the Fab fragment of the broadly neutralizing human antibody EDE2 B7 | HOMO SAPIENS; DENGUE VIRUS 2 | homo sapiens | homo sapiens | dengue virus 2 | ROUVINSKI, A., GUARDADO-CALVO, P., BARBA-SPAETH, G., DUQUERROY, S., VANEY, M.C., REY, F.A. | 3.2 | X-RAY DIFFRACTION | 0.2500 | 0.2120 | false | true | IGHV3 | IGLV2 | Lambda | null | null | null | null | null |
4fqr | q | r | 0 | Q | protein | null | broadly neutralizing antibody c05, heavy chain | VIRAL PROTEIN/IMMUNE SYSTEM | 06/25/12 | Crystal structure of broadly neutralizing antibody C05 bound to H3 influenza hemagglutinin | INFLUENZA A VIRUS; HOMO SAPIENS | homo sapiens | homo sapiens | influenza a virus | Ekiert, D.C., Wilson, I.A. | 4.1 | X-RAY DIFFRACTION | 0.334 | 0.309 | false | false | IGHV3 | IGKV1 | Kappa | 0 | -9.549709 | SPR | null | TBD |
6o3l | H | L | 0 | D | peptide | null | mper peptide, region 671-683 of hiv-1 gp41 | IMMUNE SYSTEM | 02/26/19 | Crystal structure of the Fab fragment of the human HIV-1 neutralizing antibody PGZL1.H4K3 in complex with its MPER peptide epitope (region 671-683 of HIV-1 gp41). | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Irimia, A., Wilson, I.A. | 1.98 | X-RAY DIFFRACTION | 0.211 | 0.170 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
5yd5 | A | a | 0 | B | peptide | null | peptide epitope (mutation n3a) | IMMUNE SYSTEM | 09/11/17 | Crystal structure of the scFv antibody 4B08 with epitope peptide (mutation N3A) | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | null | homo sapiens | Caaveiro, J.M.M., Miyanabe, K., Tsumoto, K. | 1.96 | X-RAY DIFFRACTION | 0.258 | 0.203 | true | true | unknown | unknown | unknown | null | null | null | null | null |
1yee | H | L | 0 | H | Hapten | PNB | 4-NITRO-BENZYLPHOSPHONOBUTANOYL-GLYCINE | CATALYTIC ANTIBODY | 04/15/97 | STRUCTURE OF A CATALYTIC ANTIBODY, IGG2A FAB FRAGMENT (D2.5) | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Golinelli-Pimpaneau, B., Knossow, M. | 2.2 | X-RAY DIFFRACTION | 0.260 | 0.204 | false | false | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
3lrh | null | I | 0 | J | peptide | null | huntingtin | IMMUNE SYSTEM | 02/11/10 | Structure of anti-huntingtin VL domain in complex with huntingtin peptide | HOMO SAPIENS; SYNTHETIC CONSTRUCT | null | homo sapiens | null | Schiefner, A., Chatwell, L., Skerra, A. | 2.6 | X-RAY DIFFRACTION | 0.278 | 0.216 | false | true | null | IGLV1 | Lambda | 0 | -10.022811 | Unknown | null | TBD |
6b14 | H | L | 0 | R | nucleic-acid | null | rna (86-mer) | RNA/IMMUNE SYSTEM | 09/16/17 | Spinach RNA aptamer - Fab BL3-6 S to N mutant complex | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | synthetic construct | DasGupta, S., Shelke, S.A., Piccirilli, J.A. | 1.64 | X-RAY DIFFRACTION | 0.227 | 0.212 | false | true | IGHV3 | IGKV1 | Kappa | 0 | -11.324631 | Unknown | null | TBD |
4f57 | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 05/12/12 | Fab structure of a neutralizing antibody L1 from an early subtype A HIV-1 infected patient | HOMO SAPIENS | homo sapiens | homo sapiens | null | Pan, R.M., Kong, X.P. | 1.7 | X-RAY DIFFRACTION | 0.209 | 0.186 | false | false | IGHV3 | IGLV2 | Lambda | null | null | null | null | null |
2vdq | H | L | 0 | A | protein | null | integrin alpha-iib | CELL ADHESION/IMMUNE SYSTEM | 10/10/07 | Integrin AlphaIIbBeta3 Headpiece Bound to a Chimeric Fibrinogen Gamma chain peptide, HHLGGAKQRGDV | HOMO SAPIENS; MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | homo sapiens | Springer, T., Zhu, J., Xiao, T. | 2.59 | X-RAY DIFFRACTION | 0.190 | 0.141 | false | false | IGHV14 | IGKV14 | Kappa | null | null | null | null | null |
1dbj | H | L | 0 | H | Hapten | AE2 | AETIOCHOLANOLONE | IMMUNOGLOBULIN | 08/24/93 | MOLECULAR BASIS OF CROSS-REACTIVITY AND THE LIMITS OF ANTIBODY-ANTIGEN COMPLEMENTARITY | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Arevalo, J.H., Wilson, I.A. | 2.7 | X-RAY DIFFRACTION | unknown | 0.214 | false | true | IGHV9 | IGKV1 | Kappa | null | null | null | null | null |
7t0r | C | B | 0 | D | protein | null | t-cell surface glycoprotein cd4 | ANTIVIRAL PROTEIN | 11/30/21 | Crystal structure of the anti-CD4 adnectin 6940_B01 as a complex with the extracellular domains of CD4 and ibalizumab fAb | MUS MUSCULUS; HOMO SAPIENS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | homo sapiens | Williams, S.P., Concha, N.O., Wensel, D.L., Hong, X. | 3.65 | X-RAY DIFFRACTION | 0.292 | 0.226 | false | true | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
6fy3 | X | Y | 0 | Z | peptide | null | cap45 v2 peptide | IMMUNE SYSTEM | 03/10/18 | Crystal structure of a V2-directed, RV144 vaccine-like antibody from HIV-1 infection, CAP228-3D, bound to a heterologous V2 peptide | HOMO SAPIENS; HUMAN IMMUNODEFICIENCY VIRUS 1 | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Wibmer, C.K., Moore, P.L., Morris, L. | 2.6 | X-RAY DIFFRACTION | 0.250 | 0.220 | false | true | IGHV5 | IGLV6 | Lambda | null | null | null | null | null |
5o1r | I | M | 0 | B | protein | null | gna2132 | IMMUNE SYSTEM | 05/19/17 | human Fab 5H2 bound to NHBA-C3 from Neisseria meningitidis serogroup B | NEISSERIA MENINGITIDIS; HOMO SAPIENS | homo sapiens | homo sapiens | neisseria meningitidis | Enrico, M., Maritan, M. | 2.86 | X-RAY DIFFRACTION | 0.222 | 0.178 | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
4tnw | W | f | 0 | P | protein | null | avermectin-sensitive glutamate-gated chloride channel gluclalpha | TRANSPORT PROTEIN/IMMUNE SYSTEM | 06/05/14 | C. elegans glutamate-gated chloride channel (GluCl) in complex with Fab and POPC in a lipid-modulated conformation | CAENORHABDITIS ELEGANS; MUS MUSCULUS | mus musculus | mus musculus | caenorhabditis elegans | Althoff, T., Hibbs, R.E., Banerjee, S., Gouaux, E. | 3.2 | X-RAY DIFFRACTION | 0.251 | 0.227 | false | false | unknown | unknown | unknown | null | null | null | null | null |
5te6 | H | L | 0 | G | protein | null | clade a/e 93th057 hiv-1 gp120 core | IMMUNE SYSTEM | 09/20/16 | Crystal Structure of Broadly Neutralizing VRC01-class Antibody N6 in complex with HIV-1 Clade AE strain 93TH057 core gp120 | HOMO SAPIENS; HUMAN IMMUNODEFICIENCY VIRUS 1 | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Zhou, T., Kwong, P.D. | 2.4 | X-RAY DIFFRACTION | 0.278 | 0.227 | false | true | unknown | unknown | unknown | 0 | -11.714355 | SPR | null | TBD |
4lbe | A | B | 0 | C | protein | null | ph-gated potassium channel kcsa | TRANSPORT PROTEIN, membrane protein | 06/20/13 | Structure of KcsA with R122A mutation | STREPTOMYCES LIVIDANS; MUS MUSCULUS | mus musculus | mus musculus | streptomyces lividans | Nimigean, C.M., Posson, D.J., McCoy, J.M. | 2.751 | X-RAY DIFFRACTION | 0.202 | 0.167 | false | true | IGHV1 | IGKV5 | Kappa | null | null | null | null | null |
5fyl | D | E | 0 | B | protein | null | bg505 gp120 env ectodomain | null | 03/08/16 | Crystal Structure at 3.7 A Resolution of Fully Glycosylated HIV-1 Clade A BG505 SOSIP.664 Prefusion Env Trimer in Complex with Broadly Neutralizing Antibodies PGT122 and 35O22 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Stewart-Jones, G.B.E., Zhou, T., Kwong, P.D. | 3.1 | X-RAY DIFFRACTION | 0.3072 | 0.2503 | false | true | unknown | unknown | unknown | null | null | null | null | null |
6itq | D | null | 0 | D | Hapten | HCY | (11ALPHA,14BETA)-11,17,21-TRIHYDROXYPREGN-4-ENE-3,20-DIONE | IMMUNE SYSTEM | 11/24/18 | Crystal structure of cortisol complexed with its nanobody at pH 10.5 | CAMELUS BACTRIANUS | camelus bactrianus | null | camelus bactrianus | Ding, Y., Ding, L.L., Wang, Z.Y., Zhong, P.Y. | 1.526 | X-RAY DIFFRACTION | 0.256 | 0.223 | false | true | unknown | unknown | unknown | null | null | null | null | null |
6m0z | H | L | 0 | A | protein | null | sodium-dependent dopamine transporter | MEMBRANE PROTEIN | 02/24/20 | X-ray structure of Drosophila dopamine transporter with NET-like mutations (D121G/S426M/F471L) in L-norepinephrine bound form | DROSOPHILA MELANOGASTER; MUS MUSCULUS | mus musculus | mus musculus | drosophila melanogaster | Shabareesh, P., Mallela, A.K., Joseph, D., Penmatsa, A. | 2.88 | X-RAY DIFFRACTION | 0.243 | 0.213 | false | true | IGHV5 | IGKV4 | Kappa | null | null | null | null | null |
6pv7 | F | G | 0 | D | E | protein | protein | NA | NA | fusion protein of neuronal acetylcholine receptor subunitalpha-3 and soluble cytochrome b562 | fusion protein of neuronal acetylcholine receptor subunitbeta-4 and soluble cytochrome b562 | MEMBRANE PROTEIN | 07/19/19 | Human alpha3beta4 nicotinic acetylcholine receptor in complex with nicotine | HOMO SAPIENS; ESCHERICHIA COLI O11; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens, escherichia coli o11 | homo sapiens, escherichia coli o11 | Gharpure, A., Teng, J., Zhuang, Y., Noviello, C.M., Walsh, R.M., Cabuco, R., Howard, R.J., Zaveri, N.T., Lindahl, E., Hibbs, R.E. | 3.34 | ELECTRON MICROSCOPY | null | null | false | false | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
3qyc | A | null | 0 | null | null | null | null | IMMUNE SYSTEM | 03/03/11 | Structure of a dimeric anti-HER2 single domain antibody | null | homo sapiens | null | null | Baral, T.N., Chao, S., Li, S., Tanha, J., Arbabai, M., Wang, S., Zhang, J. | 1.6 | X-RAY DIFFRACTION | 0.229 | 0.209 | false | true | IGHV3 | null | null | null | null | null | null | null |
6ym0 | H | L | 0 | E | protein | null | rbd | VIRAL PROTEIN | 04/07/20 | Crystal structure of the SARS-CoV-2 receptor binding domain in complex with CR3022 Fab (crystal form 1) | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Huo, J., Zhao, Y., Ren, J., Zhou, D., Ginn, H.M., Fry, E.E., Owens, R., Stuart, D.I. | 4.36 | X-RAY DIFFRACTION | 0.319 | 0.323 | false | true | IGHV5 | IGKV4 | Kappa | null | null | null | null | null |
6tcp | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 11/06/19 | Crystal structure of the omalizumab Fab Leu158Pro light chain mutant - crystal form II | HOMO SAPIENS | homo sapiens | homo sapiens | null | Mitropoulou, A.N., Ceska, T., Beavil, A.J., Henry, A.J., McDonnell, J.M., Sutton, B.J., Davies, A.M. | 2.5 | X-RAY DIFFRACTION | 0.239 | 0.212 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
1eeu | null | B | 0 | null | null | null | null | IMMUNE SYSTEM | 02/03/00 | M4L/Y(27D)D/Q89D/T94H mutant of LEN | HOMO SAPIENS | null | homo sapiens | null | Pokkuluri, P.R., Cai, X., Gu, M., Stevens, F.J., Schiffer, M. | 1.6 | X-RAY DIFFRACTION | 0.222 | 0.194 | false | true | null | IGKV4 | Kappa | null | null | null | null | null |
6os0 | D | null | 0 | A | protein | null | type-1 angiotensin ii receptor,soluble cytochrome b562 brilfusion protein | MEMBRANE PROTEIN | 05/01/19 | Structure of synthetic nanobody-stabilized angiotensin II type 1 receptor bound to angiotensin II | HOMO SAPIENS; ESCHERICHIA COLI; SYNTHETIC CONSTRUCT; SYNTHETIC CONSTRUCT | synthetic construct | null | homo sapiens, escherichia coli | Wingler, L.M., Staus, D.P., Skiba, M.A., McMahon, C., Kleinhenz, A.L.W., Lefkowitz, R.J., Kruse, A.C. | 2.9 | X-RAY DIFFRACTION | 0.318 | 0.259 | false | true | IGHV1 | null | null | null | null | null | null | null |
1rz8 | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 12/24/03 | CRYSTAL STRUCTURE OF HUMAN ANTI-HIV-1 GP120-REACTIVE ANTIBODY 17B | HOMO SAPIENS | homo sapiens | homo sapiens | null | Huang, C.C., Venturi, M., Majeed, S., Moore, M.J., Phogat, S., Zhang, M.-Y., Dimitrov, D.S., Hendrickson, W.A., Robinson, J., Sodroski, J., Wyatt, R., Choe, H., Farzan, M., Kwong, P.D. | 2.3 | X-RAY DIFFRACTION | 0.262 | 0.212 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
7whk | D | null | 0 | C | protein | null | spike glycoprotein | VIRAL PROTEIN | 12/30/21 | The state 3 complex structure of Omicron spike with Bn03 (2-up RBD, 5 nanobodies) | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | null | severe acute respiratory syndrome coronavirus2 | Zhan, W.Q., Zhang, X., Chen, Z.G., Sun, L. | 3.01 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | null | null | null | null | null | null | null |
7m7w | E | F | 0 | R | protein | null | spike protein s1 | VIRAL PROTEIN/IMMUNE SYSTEM | 03/29/21 | Antibodies to the SARS-CoV-2 receptor-binding domain that maximize breadth and resistance to viral escape | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Snell, G., Czudnochowski, N., Croll, T.I., Nix, J.C., Corti, D., Cameroni, E., Pinto, D., Beltramello, M. | 2.65 | X-RAY DIFFRACTION | 0.271 | 0.221 | false | true | IGHV5 | IGLV2 | Lambda | null | null | null | null | null |
6zwk | A | null | 0 | G | peptide | null | histone h2ax | IMMUNE SYSTEM | 07/28/20 | Crystal structure of the phosphorylated C-terminal tail of histone H2AX in complex with a specific nanobody (C6 gammaXbody) | VICUGNA PACOS; SYNTHETIC CONSTRUCT | vicugna pacos | null | homo sapiens | McEwen, A.G., Moeglin, E., Desplancq, D., Weiss, E., Poterszman, A. | 1.55 | X-RAY DIFFRACTION | 0.184 | 0.149 | false | true | IGHV1 | null | null | null | null | null | null | null |
6o9h | A | B | 0 | C | protein | null | ecd | IMMUNE SYSTEM | 03/13/19 | Mouse ECD with Fab1 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Min, X., Wang, Z. | 2.1 | X-RAY DIFFRACTION | 0.248 | 0.203 | false | true | IGHV5 | IGKV8 | Kappa | null | null | null | null | null |
7dfa | H | L | 0 | A | V | protein | peptide | NA | NA | beta-arrestin-1 | varpp-4 | SIGNALING PROTEIN | 11/06/20 | Crystal of Arrestin2-V2Rpp-4-Fab30 complex | BOS TAURUS; MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | bos taurus | synthetic construct | Sun, J.P., Yu, X., Xiao, P., He, Q.T., Lin, J.Y., Zhu, Z.L. | 2.54 | X-RAY DIFFRACTION | 0.280 | 0.234 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
7mzf | H | L | 0 | A | protein | null | spike protein s1 | VIRAL PROTEIN | 05/24/21 | SARS-CoV-2 receptor binding domain bound to Fab PDI 37 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Pymm, P., Chan, L.J., Dietrich, M.H., Tan, L.L., Tham, W.H. | 2.493 | X-RAY DIFFRACTION | 0.227 | 0.185 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
5m2w | A | null | 0 | null | null | null | null | IMMUNE SYSTEM | 10/13/16 | Structure of nanobody nb18 raised against TssK from E. coli T6SS | LAMA GLAMA | lama glama | null | null | Cambillau, C., Nguyen, V.S., Spinelli, S., Desmyter, A. | 1.5 | X-RAY DIFFRACTION | 0.214 | 0.203 | false | true | IGHV1 | null | null | null | null | null | null | null |
6qtl | H | null | 0 | H | Hapten | CFF | CAFFEINE | BIOSYNTHETIC PROTEIN | 04/10/19 | Caffeine recognizing nanobody | CAMELIDAE | camelidae | null | camelidae | Lesne, J., Guichou, J.F., Labesse, G., Cohen-Gonsaud, M. | 2.25 | X-RAY DIFFRACTION | 0.259 | 0.194 | false | true | IGHV1 | null | null | null | null | null | null | null |
6wmw | M | N | 0 | B | protein | null | gdnf family receptor alpha-like | IMMUNE SYSTEM | 04/21/20 | GFRAL receptor bound with two antibody Fabs (3P10, 25M22) | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | White, A., Lakshminarasimhan, D., Olland, A., Suto, R.K. | 2.91 | X-RAY DIFFRACTION | 0.290 | 0.222 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
7e8f | D | E | 0 | R | protein | null | spike protein s1 | VIRAL PROTEIN | 03/01/21 | SARS-CoV-2 NTD in complex with N9 Fab | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Du, S., Xiao, J., Zhang, Z. | 3.18 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
4n1e | null | F | 0 | K | protein | null | lysozyme c | Immune system/Hydrolase | 10/04/13 | Structural evidence for antigen receptor evolution | HOMO SAPIENS; GALLUS GALLUS | null | homo sapiens | gallus gallus | Langley, D.B., Rouet, R., Stock, D., Christ, D. | 2.23 | X-RAY DIFFRACTION | 0.265 | 0.223 | false | true | null | IGKV1 | Kappa | null | null | null | null | null |
7whz | C | E | 0 | A | protein | null | spike protein s1 | VIRAL PROTEIN | 01/01/22 | SARS-CoV-2 spike protein in complex with three human neutralizing antibodies | Homo sapiens; Severe acute respiratory syndrome coronavirus 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Zheng, Q., Li, S., Sun, H., Zheng, Z., Wang, S. | 3.42 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
7km5 | D | null | 0 | A | protein | null | spike protein s1 | VIRAL PROTEIN/IMMUNE SYSTEM | 11/02/20 | Crystal structure of SARS-CoV-2 RBD complexed with Nanosota-1 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; LAMA GLAMA | lama glama | null | severe acute respiratory syndrome coronavirus2 | Ye, G., Shi, K., Aihara, H., Li, F. | 3.19 | X-RAY DIFFRACTION | 0.294 | 0.247 | false | true | IGHV1 | null | null | null | null | null | null | null |
5vzx | E | I | 0 | null | null | null | null | IMMUNE SYSTEM | 05/29/17 | Crystal structure of crenezumab Fab | HOMO SAPIENS | homo sapiens | homo sapiens | null | Ultsch, M., Wang, W. | 2.501 | X-RAY DIFFRACTION | 0.230 | 0.185 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
7jkm | K | null | 0 | null | null | null | null | IMMUNE SYSTEM | 07/28/20 | REGN1 Human Fab in complex with anti-Kappa VHH domain | HOMO SAPIENS; LAMA GLAMA | lama glama | null | null | Dennis, T.N., de la Cruz, M., Williams, J.C. | 1.78 | X-RAY DIFFRACTION | 0.210 | 0.182 | false | true | IGHV1 | null | null | null | null | null | null | null |
1kn2 | H | L | 0 | L | Hapten | PNE | PARA-NITROPHENYL PHOSPHONOBUTANOYL L-ALANINE | IMMUNE SYSTEM | 12/18/01 | CATALYTIC ANTIBODY D2.3 COMPLEX | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Gigant, B., Knossow, M. | 1.9 | X-RAY DIFFRACTION | 0.238 | 0.213 | false | false | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
5dhx | B | b | 0 | C | protein | null | protein rev | IMMUNE SYSTEM | 08/31/15 | HIV-1 Rev NTD dimers with variable crossing angles | ORYCTOLAGUS CUNICULUS; HUMAN IMMUNODEFICIENCY VIRUS 1 | oryctolagus cuniculus | null | human immunodeficiency virus 1 | DiMattia, M.A., Watts, N.R., Wingfield, P.T., Grimes, J.M., Stuart, D.I., Steven, A.C. | 2.9 | X-RAY DIFFRACTION | 0.273 | 0.246 | true | true | unknown | unknown | unknown | null | null | null | null | null |
7e5r | W | R | 0 | B | protein | null | spike glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 02/20/21 | SARS-CoV-2 S trimer with three-antibody cocktail complex | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Sun, Y., Wang, L., Wang, N., Feng, R., Wang, X. | 3.6 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
5bjz | C | L | 0 | A | protein | null | maltose-binding periplasmic protein | SUGAR BINDING PROTEIN | 09/12/17 | Crystal structure of maltose binding protein in complex with an allosteric synthetic antibody | ESCHERICHIA COLI O157:H7; HOMO SAPIENS | homo sapiens | homo sapiens | escherichia coli o157 | Mukherjee, S., Kossiakoff, A.A. | 1.95 | X-RAY DIFFRACTION | 0.229 | 0.194 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
3umt | A | a | 0 | null | null | null | null | IMMUNE SYSTEM | 11/14/11 | scFv12, Anti-BclA antibody single chain variable fragment | MUS MUSCULUS | mus musculus | null | null | Pokkuluri, P.R. | 1.798 | X-RAY DIFFRACTION | 0.223 | 0.175 | true | true | unknown | unknown | unknown | null | null | null | null | null |
6uyg | A | B | 0 | E | protein | null | envelope glycoprotein e2 | IMMUNE SYSTEM | 11/13/19 | Structure of Hepatitis C Virus Envelope Glycoprotein E2c3 core from genotype 6a bound to broadly neutralizing antibody AR3B and non neutralizing antibody E1 | RECOMBINANT HEPATITIS C VIRUS HK6A/JFH-1; HOMO SAPIENS; STREPTOCOCCUS SP. | homo sapiens | homo sapiens | recombinant hepatitis c virus hk6a/jfh-1 | Tzarum, N., Wilson, I.A., Zhu, J. | 3.375 | X-RAY DIFFRACTION | 0.306 | 0.254 | false | true | IGHV1 | IGKV2 | Kappa | null | null | null | null | null |
2fl5 | F | E | 0 | F | Hapten | RBF | RIBOFLAVIN | IMMUNE SYSTEM | 01/05/06 | Cofactor-containing antibodies: Crystal structure of the original yellow antibody | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Zhu, X., Wilson, I.A. | 3.0 | X-RAY DIFFRACTION | 0.290 | 0.240 | false | false | IGHV3 | IGLV3 | Lambda | 0 | -11.929943 | Unknown | null | TBD |
7neq | F | E | 0 | A | protein | null | atp-binding cassette sub-family g member 2 | MEMBRANE PROTEIN | 02/04/21 | Structure of tariquidar-bound ABCG2 | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | Kowal, J., Locher, K. | 3.12 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV13 | Kappa | null | null | null | null | null |
6ncp | C | D | 0 | E | peptide | null | hiv-1 fusion peptide (residues 512-520) | IMMUNE SYSTEM | 12/11/18 | Crystal structure of HIV-1 broadly neutralizing antibody ACS202 | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | synthetic construct | Yuan, M., Wilson, I.A. | 2.76 | X-RAY DIFFRACTION | 0.256 | 0.222 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
4xmp | H | L | 0 | G | protein | null | envelope glycoprotein gp160,envelope glycoprotein gp160,envelope glycoprotein gp160 | IMMUNE SYSTEM | 01/15/15 | Crystal structure of broadly and potently neutralizing antibody VRC08 in complex with HIV-1 clade A strain Q842.d12 gp120 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Zhou, T., Srivatsan, S., Kwong, P.D. | 1.7831 | X-RAY DIFFRACTION | 0.201 | 0.165 | false | true | unknown | unknown | unknown | null | null | null | null | null |
3cm9 | B | M | 9 | null | null | null | null | IMMUNE SYSTEM | 03/21/08 | Solution Structure of Human SIgA2 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Bonner, A., Almogren, A., Furtado, P.B., Kerr, M.A., Perkins, S.J. | NOT | SOLUTION SCATTERING | null | null | false | false | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
5mp2 | D | null | 0 | B | protein | null | type ii secretion system protein d | TRANSPORT PROTEIN | 12/15/16 | XcpQN012 in complex with VHH04 | PSEUDOMONAS AERUGINOSA; LAMA GLAMA | lama glama | null | pseudomonas aeruginosa | Trinh, T.T.N., Roussel, A., Douzi, B., Voulhoux, R. | 2.9 | X-RAY DIFFRACTION | 0.256 | 0.213 | false | true | IGHV1 | null | null | null | null | null | null | null |
6ztr | H | L | 0 | I | protein | null | cadherin-3 | IMMUNE SYSTEM | 07/20/20 | Crystal Structure of the anti-human P-Cadherin Fab CQY684 in complex with human P-Cadherin(108-324) | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Rondeau, J.M., Lehmann, S. | 2.1 | X-RAY DIFFRACTION | 0.221 | 0.192 | false | true | IGHV6 | IGKV1 | Kappa | null | null | null | null | null |
6al4 | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 08/07/17 | CRYSTAL STRUCTURE OF ANTI-CD19 ANTIBODY B43 FAB | HOMO SAPIENS | homo sapiens | homo sapiens | null | Teplyakov, A., Obmolova, G., Gilliland, G.L. | 2.45 | X-RAY DIFFRACTION | 0.236 | 0.206 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
6qf6 | C | c | 0 | null | null | null | null | APOPTOSIS | 01/09/19 | Structure of an E.coli expressed anti-Mcl1 scFv | HOMO SAPIENS | homo sapiens | null | null | Luptak, J. | 2.59 | X-RAY DIFFRACTION | 0.262 | 0.181 | true | true | unknown | unknown | unknown | null | null | null | null | null |
7u8j | H | L | 0 | B | A | protein | protein | NA | NA | hemagglutinin ha2 subunit | hemagglutinin ha1 subunit | VIRAL PROTEIN/Immune System | 03/08/22 | Crystal structure of chimeric hemagglutinin cH4/3 in complex with broad protective antibody 31.a.83 | INFLUENZA A VIRUS; HOMO SAPIENS | homo sapiens | homo sapiens | influenza a virus | influenza a virus | Zhu, X., Wilson, I.A. | 4.9 | X-RAY DIFFRACTION | 0.340 | 0.324 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
6mug | H | L | 0 | G | protein | null | envelope glycoprotein gp160 | IMMUNE SYSTEM/INHIBITOR | 10/23/18 | Crystal Structure of HIV-1 B41 SOSIP.664 Prefusion Env Trimer Bound to Small Molecule HIV-1 Entry Inhibitor BMS-386150 in Complex with Human Antibodies 3H109L and 35O22 at 3.8 Angstrom | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Lai, Y.-T., Kwong, P.D. | 2.954 | X-RAY DIFFRACTION | 0.290 | 0.230 | false | true | IGHV4 | unknown | unknown | null | null | null | null | null |
4unt | null | B | 0 | null | null | null | null | IMMUNE SYSTEM | 05/30/14 | Induced monomer of the Mcg variable domain | HOMO SAPIENS | null | homo sapiens | null | Brumshtein, B., Esswein, S.R., Landau, M., Ryan, C.M., Whitelegge, J.P., Phillips, M.L., Cascio, D., Sawaya, M.R., Eisenberg, D.S. | 2.7 | X-RAY DIFFRACTION | 0.28925 | 0.24328 | false | true | null | IGLV2 | Lambda | null | null | null | null | null |
6nb3 | D | E | 0 | A | protein | null | spike glycoprotein | VIRUS | 12/06/18 | MERS-CoV complex with human neutralizing LCA60 antibody Fab fragment (state 1) | MIDDLE EAST RESPIRATORY SYNDROME-RELATED CORONAVIRUS; HOMO SAPIENS | homo sapiens | homo sapiens | middle east respiratory syndrome-relatedcoronavirus | Walls, A.C., Xiong, X., Park, Y.J., Tortorici, M.A., Snijder, S., Quispe, J., Cameroni, E., Gopal, R., Mian, D., Lanzavecchia, A., Zambon, M., Rey, F.A., Corti, D., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 3.5 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGLV2 | Lambda | null | null | null | null | null |
3cm9 | A | L | 7 | null | null | null | null | IMMUNE SYSTEM | 03/21/08 | Solution Structure of Human SIgA2 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Bonner, A., Almogren, A., Furtado, P.B., Kerr, M.A., Perkins, S.J. | NOT | SOLUTION SCATTERING | null | null | false | false | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
7lm8 | H | L | 0 | A | protein | null | spike protein s1 | VIRAL PROTEIN/IMMUNE SYSTEM | 02/05/21 | Crystal structure of SARS-CoV-2 spike protein receptor-binding domain in complex with two cross-neutralizing antibodies CV38-142 and COVA1-16 Fabs isolated from COVID-19 patients | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Liu, H., Wilson, I.A. | 1.936 | X-RAY DIFFRACTION | 0.201 | 0.169 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
6o2b | C | D | 0 | G | E | J | peptide | protein | protein | NA | NA | NA | circumsporozoite protein | anti-kappa vhh domain | anti-kappa vhh domain | IMMUNE SYSTEM | 02/22/19 | Crystal structure of 4493 Fab in complex with circumsporozoite protein DND and anti-kappa VHH domain | HOMO SAPIENS; LAMA GLAMA; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | plasmodium falciparum | lama glama | lama glama | Scally, S.W., Bosch, A., Prieto, K., Murugan, R., Wardemann, H., Julien, J.P. | 2.1 | X-RAY DIFFRACTION | 0.210 | 0.177 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
7z1c | E | null | 0 | C | protein | null | spike protein s1 | ANTIVIRAL PROTEIN | 02/24/22 | Nanobody H11-B5 and H11-F2 bound to RBD | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; LAMA GLAMA | lama glama | null | severe acute respiratory syndrome coronavirus2 | Mikolajek, H., Naismith, J.H. | 1.9 | X-RAY DIFFRACTION | 0.199 | 0.175 | false | true | IGHV1 | null | null | null | null | null | null | null |
2kh2 | B | b | 49 | A | protein | null | interleukin-1 beta | Cytokine/IMMUNE SYSTEM | 03/23/09 | Solution structure of a scFv-IL-1B complex | HOMO SAPIENS; MUS MUSCULUS | mus musculus | null | homo sapiens | Wilkinson, I.C., Hall, C.J., Veverka, V., Muskett, F.W., Stephens, P.E., Taylor, R.J., Henry, A.J., Carr, M.D. | NOT | SOLUTION NMR | null | null | true | true | unknown | unknown | unknown | null | null | null | null | null |
6nip | A | B | 0 | E | protein | null | envelope protein e | VIRAL PROTEIN/IMMUNE SYSTEM | 12/31/18 | Crystal structure of a human anti-ZIKV-DENV neutralizing antibody MZ1 in complex with ZIKV E glycoprotein | HOMO SAPIENS; ZIKA VIRUS (ISOLATE ZIKV/HUMAN/FRENCH POLYNESIA/10087PF/2013) | homo sapiens | homo sapiens | zika virus (isolate zikv/human/frenchpolynesia/10087pf/2013) | Sankhala, R.S., Dussupt, V., Donofrio, G., Choe, M., Modjarrad, K., Michael, N.L., Krebs, S.J., Joyce, M.G. | 4.16 | X-RAY DIFFRACTION | 0.237 | 0.188 | false | true | IGHV4 | IGLV1 | Lambda | null | null | null | null | null |
7pry | A | B | 0 | I | protein | null | surface glycoprotein | VIRAL PROTEIN | 09/22/21 | Crystal structure of the receptor binding domain of SARS-CoV-2 beta variant spike glycoprotein in complex with COVOX-45 and beta-6 Fabs | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Zhou, D., Ren, J., Stuart, D.I. | 3.1 | X-RAY DIFFRACTION | 0.291 | 0.245 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
7n0i | K | null | 0 | E | F | protein | protein | NA | NA | nucleoprotein | nucleoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 05/25/21 | Structure of the SARS-CoV-2 N protein C-terminal domain bound to single-domain antibody E2 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; LAMA GLAMA | lama glama | null | severe acute respiratory syndrome coronavirus2 | severe acute respiratory syndrome coronavirus2 | Ye, Q., Corbett, K.D. | 2.2 | X-RAY DIFFRACTION | 0.271 | 0.239 | false | true | IGHV1 | null | null | null | null | null | null | null |
4lex | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 06/26/13 | Unliganded crystal structure of mAb7 | MUS MUSCULUS | mus musculus | mus musculus | null | Murray, J.M., Mukund, S. | 2.02 | X-RAY DIFFRACTION | 0.218 | 0.185 | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
5uk4 | d | null | 0 | D | protein | null | anti-vesicular stomatitis virus n vhh | Viral Protein/RNA/Immune System | 01/19/17 | VESICULAR STOMATITS VIRUS N PROTEIN IN COMPLEX WITH INHIBITORY NANOBODY 1307 | VESICULAR STOMATITIS INDIANA VIRUS (STRAIN SAN JUAN); VICUGNA PACOS | vicugna pacos | null | vesicular stomatitis indiana virus (strain sanjuan) | Hanke, L., Knockenhauer, K.E., Ploegh, H.L., Schwartz, T.U. | 3.204 | X-RAY DIFFRACTION | 0.288 | 0.237 | false | false | IGHV1 | null | null | null | null | null | null | null |
6n1v | 3 | 4 | 0 | F | protein | null | vrc03 heavy chain | VIRAL PROTEIN | 11/12/18 | Cryo-EM structure at 4.0 A resolution of vaccine-elicited antibody A12V163-a.01 in complex with HIV-1 Env BG505 DS-SOSIP, and antibodies VRC03 and PGT122 | MACACA MULATTA; HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | macaca mulatta | macaca mulatta | human immunodeficiency virus 1 | Acharya, P., Kwong, P.D. | 4 | ELECTRON MICROSCOPY | null | null | false | true | IGHV4 | IGLV1 | Lambda | null | null | null | null | null |
4w2o | C | null | 0 | D | protein | null | nucleoprotein | IMMUNE SYSTEM | 08/17/17 | Anti-Marburgvirus Nucleoprotein Single Domain Antibody B Complexed with Nucleoprotein C-terminal domain | LAMA GLAMA; LAKE VICTORIA MARBURGVIRUS (STRAIN MUSOKE-80) | lama glama | null | lake victoria marburgvirus (strain musoke-80) | Taylor, A.B., Garza, J.A. | 3.2 | X-RAY DIFFRACTION | 0.285 | 0.227 | false | true | IGHV1 | null | null | null | null | null | null | null |
6e5p | O | P | 0 | C | protein | null | envelope glycoprotein gp120 | VIRAL PROTEIN | 07/21/18 | Backbone model based on cryo-EM map at 8.5 A of domain-swapped, glycan-reactive, neutralizing antibody 2G12 bound to HIV-1 Env BG505 DS-SOSIP, which was also bound to CD4-binding site antibody VRC03 | HOMO SAPIENS; HUMAN IMMUNODEFICIENCY VIRUS 1 | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Acharya, P., Kwong, P.D. | 8.8 | ELECTRON MICROSCOPY | null | null | false | true | unknown | IGKV3 | Kappa | null | null | null | null | null |
7lxy | F | C | 0 | B | protein | null | spike glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 03/05/21 | SARS-CoV-2 S/S2M11/S2X333 Global Refinement | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | McCallum, M., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 2.2 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
1b4j | H | L | 0 | null | null | null | null | ANTIBODY ENGINEERING | 12/22/98 | COMPARISON OF THE THREE-DIMENSIONAL STRUCTURES OF A HUMANIZED AND A CHIMERIC FAB OF AN ANTI-GAMMA-INTERFERON ANTIBODY | HOMO SAPIENS | homo sapiens | homo sapiens | null | Fan, Z., Shan, L., Goldsteen, B.Z., Guddat, L.W., Thakur, A., Landolfi, N.F., Co, M.S., Vasques, M., Queen, C., Ramsland, P.A., Edmundson, A.B. | 2.9 | X-RAY DIFFRACTION | 0.330 | 0.193 | false | false | IGHV1 | IGKV6 | Kappa | null | null | null | null | null |
7kqk | H | L | 0 | P | peptide | null | ptau peptide | IMMUNE SYSTEM | 11/16/20 | anti-pTau C21-ABS Fab in complex with pTau peptide | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | homo sapiens | Mosyak, L., Brinth, A. | 2.6 | X-RAY DIFFRACTION | 0.231 | 0.211 | false | true | IGHV3 | IGLV3 | Lambda | null | null | null | null | null |
6ot1 | F | I | 0 | E | protein | null | bg505 gp120 | IMMUNE SYSTEM | 05/02/19 | Cryo-EM structure of vaccine-elicited antibody 0PV-b.01 in complex with HIV-1 Env BG505 DS-SOSIP and antibodies VRC03 and PGT122 | HUMAN IMMUNODEFICIENCY VIRUS 1; MACACA MULATTA; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Gorman, J., Kwong, P.D. | 3.5 | ELECTRON MICROSCOPY | null | null | false | true | IGHV4 | unknown | unknown | null | null | null | null | null |
6jb5 | A | null | 0 | B | protein | null | lysozyme c | IMMUNE SYSTEM/HYDROLASE | 01/25/19 | Crystal structure of nanobody D3-L11 mutant Y102A in complex with hen egg-white lysozyme (form II) | CAMELUS DROMEDARIUS; GALLUS GALLUS | camelus dromedarius | null | gallus gallus | Caaveiro, J.M.M., Tamura, H., Akiba, H., Tsumoto, K. | 1.55 | X-RAY DIFFRACTION | 0.169 | 0.132 | false | true | IGHV1 | null | null | null | null | null | null | null |
6pdu | H | L | 0 | C | peptide | null | hiv-1 fusion peptide residue 512-519 | IMMUNE SYSTEM | 06/19/19 | Vaccine-elicited NHP FP-targeting antibody 13N024-a.01 in complex with HIV fusion peptide (residue 512-519) | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Xu, K., Liu, K., Wang, Y., Kwong, P.D. | 1.953 | X-RAY DIFFRACTION | 0.211 | 0.173 | false | true | IGHV3 | IGKV2 | Kappa | null | null | null | null | null |
4tnw | Y | g | 0 | T | protein | null | avermectin-sensitive glutamate-gated chloride channel gluclalpha | TRANSPORT PROTEIN/IMMUNE SYSTEM | 06/05/14 | C. elegans glutamate-gated chloride channel (GluCl) in complex with Fab and POPC in a lipid-modulated conformation | CAENORHABDITIS ELEGANS; MUS MUSCULUS | mus musculus | mus musculus | caenorhabditis elegans | Althoff, T., Hibbs, R.E., Banerjee, S., Gouaux, E. | 3.2 | X-RAY DIFFRACTION | 0.251 | 0.227 | false | false | unknown | unknown | unknown | null | null | null | null | null |
5a1z | G | H | 0 | A | protein | null | envelope protein | null | 05/06/15 | Cryo-EM structure of Dengue virus serotype 2 strain PVP94-07 complexed with human antibody 2D22 Fab at 37 degrees C | DENGUE VIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | dengue virus 2 | Fibriansah, G., Ibarra, K.D., Ng, T.S., Smith, S.A., Tan, J.L., Lim, X.N., Ooi, J.S.G., Kostyuchenko, V.A., Wang, J., de Silva, A.M., Harris, E., Crowe Jr, J.E., Lok, S.M. | 6.9 | ELECTRON MICROSCOPY | null | null | false | false | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
7wef | C | L | 0 | E | protein | null | spike protein s1 | IMMUNE SYSTEM/VIRAL PROTEIN | 12/23/21 | SARS-CoV-2 Omicron variant spike RBD in complex with Fab XGv289 | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Wang, X., Wang, L. | 3.8 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
5xhg | D | C | 0 | null | null | null | null | IMMUNE SYSTEM | 04/20/17 | Crystal structure of Trastuzumab Fab fragment bearing Ne-(o-azidobenzyloxycarbonyl)-L-lysine | ESCHERICHIA COLI STR. K-12 SUBSTR. W3110 | escherichia coli str. k-12 substr. w3110 | escherichia coli str. k-12 substr. w3110 | null | Kuratani, M., Yanagisawa, T., Sakamoto, K., Yokoyama, S. | 1.76 | X-RAY DIFFRACTION | 0.199 | 0.173 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
4z5r | B | A | 0 | N | protein | null | interferon alpha-2 | Cytokine/Immune System | 04/02/15 | Rontalizumab Fab bound to Interferon-a2 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Eigenbrot, C., Maurer, B., Bosanac, I. | 3.0 | X-RAY DIFFRACTION | 0.251 | 0.223 | false | true | IGHV3 | IGKV1 | Kappa | 0 | -14.658431 | SPR | null | TBD |
4olw | H | L | 0 | G | protein | null | envelope glycoprotein gp160 | VIRAL PROTEIN/IMMUNE SYSTEM | 01/25/14 | Crystal structure of antibody VRC07-G54H in complex with clade A/E 93TH057 HIV-1 gp120 core | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Kwon, Y.D., Kwong, P.D. | 2.709 | X-RAY DIFFRACTION | 0.257 | 0.196 | false | true | unknown | IGKV3 | Kappa | null | null | null | null | null |
7lpn | D | null | 0 | C | protein | null | envelope glycoprotein gp160 | VIRAL PROTEIN | 02/12/21 | Cryo-EM structure of llama J3 VHH antibody in complex with HIV-1 Env BG505 DS-SOSIP.664 | HUMAN IMMUNODEFICIENCY VIRUS 1; LAMA GLAMA | lama glama | null | human immunodeficiency virus 1 | Gorman, J., Kwong, P.D. | 3.61 | ELECTRON MICROSCOPY | null | null | false | true | unknown | unknown | unknown | null | null | null | null | null |
4r4n | Q | R | 0 | P | b | protein | peptide | NA | NA | m48u1 peptide | unknown | VIRAL PROTEIN/IMMUNE SYSTEM/INHIBITOR | 08/19/14 | Crystal structure of the anti-hiv-1 antibody 2.2c in complex with hiv-1 93ug037 gp120 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | human immunodeficiency virus 1 | synthetic construct | Acharya, P., Louder, R., Kwong, P.D. | 3.56 | X-RAY DIFFRACTION | 0.328 | 0.296 | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
3cm9 | C | N | 7 | null | null | null | null | IMMUNE SYSTEM | 03/21/08 | Solution Structure of Human SIgA2 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Bonner, A., Almogren, A., Furtado, P.B., Kerr, M.A., Perkins, S.J. | NOT | SOLUTION SCATTERING | null | null | false | false | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
6qv2 | F | null | 0 | D | protein | null | uncharacterized abc transporter atp-binding proteintm_0288 | MEMBRANE PROTEIN | 03/01/19 | Structure of ATPgS-bound outward-facing TM287/288 in complex with nanobody Nb_TM#2 | THERMOTOGA MARITIMA (STRAIN ATCC 43589 / MSB8 / DSM 3109 / JCM 10099); VICUGNA PACOS | vicugna pacos | null | thermotoga maritima (strain atcc 43589 / msb8 /dsm 3109 / jcm 10099) | Hutter, C.A.J., Huerlimann, L.M., Zimmermann, I., Egloff, P., Seeger, M.A. | 4.23 | X-RAY DIFFRACTION | 0.330 | 0.306 | false | true | IGHV1 | null | null | null | null | null | null | null |
2bse | D | null | 0 | B | protein | null | receptor binding protein | RECEPTOR | 05/20/05 | Structure of Lactococcal Bacteriophage p2 Receptor Binding Protein in complex with a llama VHH domain | LACTOCOCCUS LACTIS PHAGE P2; LAMA GLAMA | lama glama | null | lactococcus lactis phage p2 | Spinelli1, S., Desmyter, A., Verrips, C.T., deHaard, H.J.W., Moineau, S., Cambillau, C. | 2.7 | X-RAY DIFFRACTION | 0.294 | 0.251 | false | true | IGHV1 | null | null | null | null | null | null | null |
7ceb | C | D | 0 | B | protein | null | integrin beta-1 | CELL ADHESION/IMMUNE SYSTEM | 06/22/20 | Crystal structure of alpha6beta1 integrin headpiece | HOMO SAPIENS; MUS MUSCULUS | mus musculus, homo sapiens | mus musculus, homo sapiens | homo sapiens | Arimori, T., Takagi, J. | 2.89 | X-RAY DIFFRACTION | 0.249 | 0.207 | false | true | IGHV5 | IGKV4 | Kappa | null | null | null | null | null |
7kgu | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 10/18/20 | Structure of 2Q1-Fab, an antibody selective for IDH2R140Q-HLA-B*07:02 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Miller, M.S., Aytenfisu, T.Y., Wright, K.M., Gabelli, S.B. | 2.4 | X-RAY DIFFRACTION | 0.269 | 0.208 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
7d0b | H | L | 0 | A | protein | null | spike glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 09/09/20 | S protein of SARS-CoV-2 in complex bound with P5A-3C12_1B | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Yan, R.H., Wang, R.K., Ju, B., Yu, J.F., Zhang, Y.Y., Liu, N., Wang, H.W., Wang, X.Q., Zhang, L.Q., Zhou, Q. | 3.9 | ELECTRON MICROSCOPY | null | null | false | true | IGHV2 | IGKV4 | Kappa | null | null | null | null | null |
6o2b | A | B | 0 | F | peptide | null | circumsporozoite protein | IMMUNE SYSTEM | 02/22/19 | Crystal structure of 4493 Fab in complex with circumsporozoite protein DND and anti-kappa VHH domain | HOMO SAPIENS; LAMA GLAMA; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | plasmodium falciparum | Scally, S.W., Bosch, A., Prieto, K., Murugan, R., Wardemann, H., Julien, J.P. | 2.1 | X-RAY DIFFRACTION | 0.210 | 0.177 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
6s3d | E | F | 0 | O | protein | null | s0_2.126 | ANTIVIRAL PROTEIN | 06/25/19 | Structure of D25 Fab in complex with scaffold S0_2.126 | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | synthetic construct | Cramer, J.T., Krey, T. | 3.0 | X-RAY DIFFRACTION | 0.292 | 0.269 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
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