pdb stringlengths 4 4 | Hchain stringclasses 59
values | Lchain stringclasses 60
values | model int64 0 76 | antigen_chain stringclasses 386
values | antigen_type stringclasses 24
values | antigen_het_name stringclasses 240
values | antigen_name stringlengths 1 396 ⌀ | short_header stringclasses 448
values | date stringlengths 8 8 | compound stringlengths 4 243 | organism stringlengths 3 175 ⌀ | heavy_species stringclasses 121
values | light_species stringclasses 67
values | antigen_species stringclasses 937
values | authors stringlengths 6 762 | resolution stringlengths 1 8 | method stringclasses 10
values | r_free stringclasses 354
values | r_factor stringclasses 342
values | scfv bool 2
classes | engineered bool 2
classes | heavy_subclass stringclasses 14
values | light_subclass stringclasses 35
values | light_ctype stringclasses 3
values | affinity float64 0 0 ⌀ | delta_g float64 -16.91 -5.04 ⌀ | affinity_method stringclasses 11
values | temperature float64 4 37 ⌀ | pmid stringclasses 157
values |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5vj6 | M | N | 0 | B | protein | null | envelope glycoprotein gp160 | VIRAL PROTEIN/IMMUNE SYSTEM | 04/18/17 | BG505 SOSIP.664 in complex with broadly neutralizing antibodies PG9 and 8ANC195 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Wang, H., Bjorkman, P.J. | 11.5 | ELECTRON MICROSCOPY | null | null | false | true | unknown | IGKV1 | Kappa | null | null | null | null | null |
6qn7 | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 02/10/19 | Structure of bovine anti-RSV hybrid Fab B4HC-B13LC | BOS TAURUS | bos taurus | bos taurus | null | Ren, J., Nettleship, J.E., Harris, G., Mwangi, W., Rhaman, N., Grant, C., Kotecha, A., Fry, E., Charleston, B., Stuart, D.I., Hammond, J., Owens, R.J. | 2.15 | X-RAY DIFFRACTION | 0.234 | 0.203 | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
6ze1 | B | null | 0 | A | protein | null | cystic fibrosis transmembrane conductance regulator | HYDROLASE | 06/15/20 | human NBD1 of CFTR in complex with nanobody G11a | HOMO SAPIENS; LAMA GLAMA | lama glama | null | homo sapiens | Garcia-Pino, A., Govaerts, C., Scholl, D., Sigoillot, M. | 2.705 | X-RAY DIFFRACTION | 0.258 | 0.207 | false | true | unknown | unknown | unknown | null | null | null | null | null |
1axs | B | A | 0 | B | Hapten | HOP | (1S,2S,5S)2-(4-GLUTARIDYLBENZYL)-5-PHENYL-1-CYCLOHEXANOL | CATALYTIC ANTIBODY | 10/20/97 | MATURE OXY-COPE CATALYTIC ANTIBODY WITH HAPTEN | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Mundorff, E.C., Ulrich, H.D., Stevens, R.C. | 2.6 | X-RAY DIFFRACTION | 0.305 | 0.200 | false | true | IGHV1 | IGKV14 | Kappa | 0 | -10.599564 | Unknown | null | TBD |
6xcj | H | L | 0 | G | protein | null | envelope glycoprotein gp120 | VIRAL PROTEIN/IMMUNE SYSTEM | 06/08/20 | Crystal Structure of DH650 Fab from a Rhesus Macaque in Complex with HIV-1 gp120 Core | HUMAN IMMUNODEFICIENCY VIRUS 1; MACACA MULATTA | macaca mulatta | macaca mulatta | human immunodeficiency virus 1 | Raymond, D.D., Chug, H., Harrison, S.C. | 2.8 | X-RAY DIFFRACTION | 0.284 | 0.227 | false | true | IGHV1 | IGKV2 | Kappa | null | null | null | null | null |
6uig | B | C | 0 | A | protein | null | hemagglutinin | ANTIVIRAL PROTEIN | 09/30/19 | Crystal structure of human monoclonal antibody H7.200 in complex with H7N9 hemagglutinin HA1 | INFLUENZA A VIRUS; HOMO SAPIENS | homo sapiens | homo sapiens | influenza a virus | Dong, J., Crowe, J.E. | 3.2 | X-RAY DIFFRACTION | 0.234 | 0.207 | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
5bk1 | H | L | 0 | A | protein | null | maltose binding protein | SUGAR BINDING PROTEIN | 09/12/17 | Crystal structure of maltose binding protein in complex with an endosteric synthetic antibody | HOMO SAPIENS; ESCHERICHIA COLI | homo sapiens | homo sapiens | escherichia coli | Mukherjee, S., Kossiakoff, A.A. | 2.15 | X-RAY DIFFRACTION | 0.253 | 0.205 | false | true | IGHV3 | IGKV1 | Kappa | 0 | -12.221727 | SPR | null | TBD |
6idh | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 09/10/18 | Antibody 64M-5 Fab in ligand-free form | MUS MUSCULUS | mus musculus | mus musculus | null | Yokoyama, H., Mizutani, R., Noguchi, S., Hayashida, N. | 2.5 | X-RAY DIFFRACTION | 0.281 | 0.229 | false | false | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
7p6k | H | null | 0 | D | protein | null | volume-regulated anion channel subunit lrrc8a | MEMBRANE PROTEIN | 07/16/21 | Structure of homomeric LRRC8A Volume-Regulated Anion Channel in complex with synthetic nanobody Sb5 | MUS MUSCULUS; SYNTHETIC CONSTRUCT | synthetic construct | null | mus musculus | Deneka, D., Rutz, S., Sawicka, M. | 3.8 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
4xwo | C | D | 0 | A | protein | null | sec22 | HYDROLASE/TRANSPORT PROTEIN | 01/29/15 | Structure of Get3 bound to the transmembrane domain of Sec22 | HOMO SAPIENS, SYNTHETIC CONSTRUCT; SACCHAROMYCES CEREVISIAE (ATCC 204508 / S288C); SACCHAROMYCES CEREVISIAE | homo sapiens, synthetic construct | homo sapiens, synthetic construct | saccharomyces cerevisiae (atcc 204508 / s288c) | Mateja, A., Paduch, M., Chang, H.-Y., Szydlowska, A., Kossiakoff, A.A., Hegde, R.S., Keenan, R.J. | 2.75 | X-RAY DIFFRACTION | 0.247 | 0.196 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
7bm5 | I | G | 0 | null | null | null | null | IMMUNE SYSTEM | 01/19/21 | Crystal structure of Fab1, the Fab fragment of the anti-BamA monoclonal antibody MAB1 | HOMO SAPIENS | homo sapiens | homo sapiens | null | White, P., Storek, K.M., Rutherford, S.T., Radford, S.E. | 2.95 | X-RAY DIFFRACTION | 0.290 | 0.257 | false | true | IGHV5 | IGKV12 | Kappa | null | null | null | null | null |
7cwu | H | L | 0 | B | protein | null | spike glycoprotein | VIRAL PROTEIN | 08/31/20 | SARS-CoV-2 spike proteins trimer in complex with P17 and FC05 Fabs cocktail | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Wang, X., Wang, N. | 3.5 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
7stz | I | M | 0 | D | protein | null | cadherin-1 | cell adhesion/immune system | 11/15/21 | Crystal Structure of Human E-cadherin EC1-5 bound by mouse monoclonal antibody Fab mAb-1_19A11 | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 2.95 | X-RAY DIFFRACTION | 0.208 | 0.182 | false | true | IGHV2 | IGKV8 | Kappa | null | null | null | null | null |
7lab | Y | X | 0 | B | protein | null | spike glycoprotein | VIRAL PROTEIN, IMMUNE SYSTEM | 01/06/21 | Structure of SARS-CoV-2 S protein in complex with N-terminal domain antibody DH1052 | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Manne, K., Acharya, P. | 2.97 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
5f97 | H | null | 0 | D | protein | null | adhesin binding fucosylated histo-blood group antigen,adhesin,adhesin binding fucosylated histo-blood group antigen | CELL ADHESION | 12/09/15 | Blood group antigen binding adhesin BabA of Helicobacter pylori strain A730 in complex with blood group A type 1 hexasaccharide | HELICOBACTER PYLORI; LAMA GLAMA | lama glama | null | helicobacter pylori | Moonens, K., Gideonsson, P., Subedi, S., Romao, E., Oscarson, S., Muyldermans, S., Boren, T., Remaut, H. | 2.62 | X-RAY DIFFRACTION | 0.237 | 0.188 | false | true | IGHV1 | null | null | null | null | null | null | null |
7deo | A | a | 0 | B | protein | null | spike protein s1 | VIRAL PROTEIN/ANTIVIRAL PROTEIN | 11/04/20 | Crystal structure of SARS-CoV-2 RBD in complex with a neutralizing antibody scFv | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | null | severe acute respiratory syndrome coronavirus2 | Fu, D., Zhang, G., Li, X., Rao, Z., Guo, Y. | 2.5 | X-RAY DIFFRACTION | 0.232 | 0.187 | true | true | unknown | unknown | unknown | null | null | null | null | null |
3qcv | I | M | 0 | I | Hapten | 18L | (2R)-2-HYDROXY-3-(PHOSPHONOOXY)PROPYL (9Z,12Z)-OCTADECA-9,12-DIENOATE | IMMUNE SYSTEM | 01/17/11 | Crystal structure of the LT3015 antibody Fab fragment in complex with lysophosphatidic acid (18:2) | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Fleming, J.K., Wojciak, J.M., Campbell, M.-A., Huxford, T. | 2.51 | X-RAY DIFFRACTION | 0.266 | 0.215 | false | true | IGHV5 | IGKV2D | Kappa | null | null | null | null | null |
4wht | C | D | 0 | c | peptide | null | unknown | VIRAL PROTEIN | 09/23/14 | Structure of the Hepatitis C virus envelope glycoprotein E2 antigenic region 412-423 bound to the broadly neutralizing antibody 3/11, P1 crystal form | HEPATITIS C VIRUS; RATTUS NORVEGICUS | rattus norvegicus | rattus norvegicus | hepatitis c virus | Krey, T., Rey, F.A. | 2.22 | X-RAY DIFFRACTION | 0.243 | 0.209 | false | true | IGHV5 | IGKV2 | Kappa | 0 | -11.053614 | Unknown | null | TBD |
4nby | B | null | 0 | A | protein | null | cell wall-binding repeat protein | IMMUNE SYSTEM | 10/23/13 | Crystal Structure of TcdA-A2 Bound to Two Molecules of A20.1 VHH | CLOSTRIDIUM DIFFICILE; LAMA GLAMA | lama glama | null | clostridium difficile | Murase, T., Eugenio, L., Schorr, M., Hussack, G., Tanha, J., Kitova, E., Klassen, J.S., Ng, K.K.S. | 2.08 | X-RAY DIFFRACTION | 0.255 | 0.209 | false | true | IGHV1 | null | null | null | null | null | null | null |
6nfv | A | B | 0 | C | protein | null | ph-gated potassium channel kcsa | membrane protein, metal transport | 12/20/18 | Structure of the KcsA-G77C mutant or the 2,4-ion bound configuration of a K+ channel selectivity filter. | MUS MUSCULUS; STREPTOMYCES LIVIDANS | mus musculus | mus musculus | streptomyces lividans | Tilegenova, C., Cortes, D.M., Jahovic, N., Hardy, E., Parameswaran, H., Guan, L., Cuello, L.G. | 2.13 | X-RAY DIFFRACTION | 0.243 | 0.206 | false | true | IGHV1 | IGKV5 | Kappa | null | null | null | null | null |
5ogi | B | b | 0 | A | protein | null | hexon protein | VIRAL PROTEIN | 07/13/17 | Complex of a binding protein and human adenovirus C 5 hexon | MUS MUSCULUS; HUMAN ADENOVIRUS C SEROTYPE 5 | mus musculus | null | human adenovirus c serotype 5 | Schmid, M., Ernst, P., Honegger, A., Suomalainen, M., Zimmermann, M., Braun, L., Stauffer, S., Thom, C., Dreier, B., Eibauer, M., Kipar, A., Vogel, V., Greber, U.F., Medalia, O., Plueckthun, A. | 2.8 | X-RAY DIFFRACTION | 0.235 | 0.198 | true | true | unknown | unknown | unknown | null | null | null | null | null |
6xv8 | A | null | 0 | null | null | null | null | STRUCTURAL PROTEIN | 01/21/20 | Crystal structure of Megabody Mb-Nb207-c7HopQ_G10 | LAMA GLAMA; HELICOBACTER PYLORI (STRAIN G27) | lama glama, helicobacter pylori (strain g27) | null | null | Steyaert, J., Uchanski, T., Fischer, B. | 3.15 | X-RAY DIFFRACTION | 0.297 | 0.255 | false | true | IGHV1 | null | null | null | null | null | null | null |
1uwe | Y | X | 0 | null | null | null | null | ANTIBODY | 02/05/04 | MOLECULAR MECHANISM OF ENANTIOSELECTIVE PROTON TRANSFER TO CARBON IN CATALYTIC ANTIBODY 14D9 | MUS MUSCULUS; HOMO SAPIENS | mus musculus, homo sapiens | mus musculus, homo sapiens | null | Baumann, U., Reymond, J.L. | 2.67 | X-RAY DIFFRACTION | 0.271 | 0.218 | false | true | IGHV1 | IGKV6 | Kappa | null | null | null | null | null |
4k3h | null | H | 0 | G | Hapten | 1OM | 4-{bis[4-(dimethylamino)phenyl]methyl}phenol | immune system/inhibitor | 04/10/13 | Immunoglobulin lambda variable domain L5(L89S) fluorogen activationg protein in complex with malachite green | HOMO SAPIENS | null | homo sapiens | homo sapiens | Stanfield, R.L., Szent-Gyorgyi, C., Wilson, I.A. | 2.45 | X-RAY DIFFRACTION | 0.225 | 0.194 | false | true | null | IGLV7 | Lambda | 0 | -9.350354 | Unknown | null | TBD |
5ezi | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 11/26/15 | Crystal Structure of Fab of parasite invasion inhibitory antibody c1 - hexagonal form | HOMO SAPIENS | homo sapiens | homo sapiens | null | Favuzza, A., Pluschke, G., Rudolph, M.G. | 1.61 | X-RAY DIFFRACTION | 0.221 | 0.195 | false | true | IGHV4 | IGKV6 | Kappa | null | null | null | null | null |
5hdq | H | L | 0 | A | protein | null | abc transporter substrate-binding protein | Transport protein/Immune System | 01/05/16 | MntC co-structure with mAB 305-78-7 | STAPHYLOCOCCUS AUREUS; MUS MUSCULUS | mus musculus | mus musculus | staphylococcus aureus | Parris, K., Mosyak, L. | 1.83 | X-RAY DIFFRACTION | 0.236 | 0.207 | false | true | IGHV1 | IGKV8 | Kappa | 0 | -12.170174 | SPR | null | TBD |
1mqk | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 09/16/02 | Crystal structure of the unliganded Fv-fragment of the anti-cytochrome C oxidase antibody 7E2 | MUS MUSCULUS | mus musculus | mus musculus | null | Essen, L.-O., Harrenga, A., Ostermeier, C., Michel, H. | 1.28 | X-RAY DIFFRACTION | unknown | unknown | false | true | IGHV5 | IGKV12 | Kappa | null | null | null | null | null |
7f4h | N | null | 0 | A | B | protein | protein | NA | NA | guanine nucleotide-binding protein g(i) subunit alpha-1 | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | MEMBRANE PROTEIN | 06/18/21 | Cryo-EM structure of afamelanotide-bound melanocortin-1 receptor in complex with Gs protein, Nb35 and scFv16 | HOMO SAPIENS; SYNTHETIC CONSTRUCT; SYNTHETIC CONSTRUCT | synthetic construct | null | homo sapiens | homo sapiens | Ma, S., Chen, Y., Dai, A., Yin, W., Guo, J., Yang, D., Zhou, F., Jiang, Y., Wang, M.-W., Xu, H.E. | 2.7 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | null | null | null | null | null | null | null |
7ps1 | A | B | 0 | E | protein | null | surface glycoprotein | VIRAL PROTEIN | 09/22/21 | Crystal structure of the receptor binding domain of SARS-CoV-2 beta variant spike glycoprotein in complex with Beta-27 Fab | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Zhou, D., Ren, J., Stuart, D.I. | 2.4 | X-RAY DIFFRACTION | 0.215 | 0.184 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
5a8h | R | Q | 0 | M | protein | null | hiv-1 gp120 | VIRAL PROTEIN/IMMUNE SYSTEM | 07/15/15 | cryo-ET subtomogram averaging of BG505 SOSIP.664 in complex with sCD4, 17b, and 8ANC195 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Scharf, L., Wang, H., Gao, H., Chen, S., McDowall, A., Bjorkman, P. | 23.0 | ELECTRON MICROSCOPY | null | null | false | true | unknown | IGKV1 | Kappa | null | null | null | null | null |
6fe4 | J | null | 0 | E | protein | null | shiga-like toxin 2 subunit b | TOXIN | 12/29/17 | Crystal structure of the complex between Shiga toxin Stx2 B subunit and neutralising Nb113 | ENTEROBACTERIA PHAGE 933W; VICUGNA PACOS | vicugna pacos | null | enterobacteria phage 933w | Bernedo, R., Muyldermans, S., Sterckx, Y.G.J. | 3.0 | X-RAY DIFFRACTION | 0.207 | 0.169 | false | true | IGHV3 | null | null | 0 | -10.938139 | SPR | null | TBD |
6h2y | H | L | 0 | D | protein | null | lipoprotein gna1870 | IMMUNE SYSTEM | 07/17/18 | human Fab 1E6 bound to fHbp variant 3 from Neisseria meningitidis serogroup B | NEISSERIA MENINGITIDIS; HOMO SAPIENS | homo sapiens | homo sapiens | neisseria meningitidis | Veggi, D., Bianchi, F., Cozzi, R., Malito, E., Bottomley, M.J. | 2.65 | X-RAY DIFFRACTION | 0.275 | 0.205 | false | true | IGHV1 | IGLV3 | Lambda | null | null | null | null | null |
7ws5 | G | F | 0 | B | protein | null | spike glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 01/28/22 | Structures of Omicron Spike complexes illuminate broad-spectrum neutralizing antibody development | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Guo, H., Gao, Y., Ji, X., Yang, H. | 3.7 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
7km5 | C | null | 0 | B | protein | null | spike protein s1 | VIRAL PROTEIN/IMMUNE SYSTEM | 11/02/20 | Crystal structure of SARS-CoV-2 RBD complexed with Nanosota-1 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; LAMA GLAMA | lama glama | null | severe acute respiratory syndrome coronavirus2 | Ye, G., Shi, K., Aihara, H., Li, F. | 3.19 | X-RAY DIFFRACTION | 0.294 | 0.247 | false | true | IGHV1 | null | null | null | null | null | null | null |
1mcw | null | W | 0 | null | null | null | null | IMMUNOGLOBULIN | 05/09/89 | THREE-DIMENSIONAL STRUCTURE OF A HYBRID LIGHT CHAIN DIMER. PROTEIN ENGINEERING OF A BINDING CAVITY | HOMO SAPIENS | null | homo sapiens | null | Ely, K.R., Herron, J.N., Edmundson, A.B. | 3.5 | X-RAY DIFFRACTION | unknown | unknown | false | false | null | IGLV2 | Lambda | null | null | null | null | null |
1j1x | H | L | 0 | Y | protein | null | lysozyme c | IMMUNE SYSTEM/HYDROLASE | 12/20/02 | Crystal Structure of HyHEL-10 Fv mutant LS93A complexed with hen egg white lysozyme | MUS MUSCULUS; GALLUS GALLUS | mus musculus | mus musculus | gallus gallus | Yokota, A., Tsumoto, K., Shiroishi, M., Kondo, H., Kumagai, I. | 1.8 | X-RAY DIFFRACTION | 0.217 | 0.189 | false | true | IGHV3 | IGKV5 | Kappa | null | null | null | null | null |
5mhr | M | L | 0 | D | protein | null | viral attachment protein sigma 1 | IMMUNE SYSTEM | 11/25/16 | T3D reovirus sigma1 complexed with 9BG5 Fab fragments | REOVIRUS SP.; MUS MUSCULUS | mus musculus | mus musculus | reovirus sp. | Stehle, T., Dietrich, M.H. | 3.0 | X-RAY DIFFRACTION | 0.247 | 0.212 | false | false | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
3dif | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 06/20/08 | Crystal structure of FabOX117 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Nettleship, J.E., Ren, J., Owens, R.J., Oxford Protein Production Facility (OPPF) | 2.4 | X-RAY DIFFRACTION | 0.286 | 0.219 | false | true | IGHV1 | IGKV6 | Kappa | null | null | null | null | null |
5fgb | E | B | 0 | G | peptide | null | genome polyprotein | IMMUNE SYSTEM | 12/20/15 | Three dimensional structure of broadly neutralizing human anti - Hepatitis C virus (HCV) glycoprotein E2 Fab fragment HC33.4 | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | hepatitis c virus genotype 1a (isolate h) | Girard-Blanc, C., Rey, F.A., Krey, T. | 1.65 | X-RAY DIFFRACTION | 0.190 | 0.171 | false | true | IGHV3 | IGLV3 | Lambda | null | null | null | null | null |
7f1g | D | null | 0 | A | protein | null | beta-secretase 2 | HYDROLASE | 06/09/21 | BACE2 xaperone complex with N-{3-[(4R,5R,6R)-2-amino-5-fluoro-4,6-dimethyl-5,6-dihydro-4H-1,3-thiazin-4-yl]-4-fluorophenyl}-2H,3H-[1,4]dioxino[2,3-c]pyridine-7-carboxamide | HOMO SAPIENS | homo sapiens | null | homo sapiens | Ueno, T., Matsuoka, E., Asada, N., Yamamoto, S., Kanegawa, N., Ito, M., Ito, H., Moechars, D., Rombouts, F.J.R., Gijsen, H.J.M., Kusakabe, K.I. | 1.5 | X-RAY DIFFRACTION | 0.245 | 0.226 | false | true | IGHV3 | null | null | null | null | null | null | null |
7zfa | O | P | 0 | B | protein | null | spike protein s1 | VIRAL PROTEIN | 04/01/22 | SARS-CoV-2 Omicron RBD in complex with Omi-6 and COVOX-150 Fabs | Homo sapiens; Severe acute respiratory syndrome coronavirus 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Zhou, D., Huo, J., Ren, J., Stuart, D.I. | 4.24 | X-RAY DIFFRACTION | 0.272 | 0.237 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
1xgy | H | L | 0 | P | peptide | null | rhodopsin epitope mimetic peptide | immune system | 09/17/04 | Crystal Structure of Anti-Meta I Rhodopsin Fab Fragment K42-41L | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | null | Piscitelli, C.L., Angel, T.E., Bailey, B.W., Lawerence, C.M. | 2.71 | X-RAY DIFFRACTION | 0.272 | 0.233 | false | false | IGHV1 | IGKV2 | Kappa | null | null | null | null | null |
4at6 | G | I | 0 | null | null | null | null | IMMUNE SYSTEM | 05/04/12 | Fab fragment of antiporphyrin antibody 14H7 | MUS MUSCULUS | mus musculus | mus musculus | null | Golinelli-Pimpaneau, B., Mahy, J.P. | 2.549 | X-RAY DIFFRACTION | 0.3281 | 0.2791 | false | false | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
2gsi | H | G | 0 | Z | peptide | null | thermonuclease | IMMUNE SYSTEM | 04/26/06 | Crystal Structure of a Murine Fab in Complex with an 11 Residue Peptide Derived from Staphylococcal Nuclease | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | null | Armstrong, A.A., Amzel, L.M. | 2.81 | X-RAY DIFFRACTION | 0.293 | 0.221 | false | false | IGHV14 | IGKV3 | Kappa | null | null | null | null | null |
7m2i | A | B | 0 | C | protein | null | ph-gated potassium channel kcsa | TRANSPORT PROTEIN/IMMUNE SYSTEM | 03/16/21 | Structural Snapshots of Intermediates in the Gating of a K+ Channel | MUS MUSCULUS; STREPTOMYCES LIVIDANS | mus musculus | mus musculus | streptomyces lividans | Reddi, R., Valiyaveetil, F.I. | 2.695 | X-RAY DIFFRACTION | 0.251 | 0.228 | false | true | IGHV1 | IGKV5 | Kappa | null | null | null | null | null |
6p67 | E | F | 0 | G | protein | null | interleukin-7 receptor subunit alpha | IMMUNE SYSTEM | 06/03/19 | Crystal Structure of a Complex of human IL-7Ralpha with an anti-IL-7Ralpha 2B8 Fab | MUS MUSCULUS; HOMO SAPIENS | mus musculus | mus musculus | homo sapiens | Walsh, S.T.R., Kashi, L., Kohnhorst, C.L. | 2.9 | X-RAY DIFFRACTION | 0.266 | 0.249 | false | true | IGHV1 | IGKV6 | Kappa | null | null | null | null | null |
3mnw | B | A | 0 | P | peptide | null | gp41 | IMMUNE SYSTEM | 04/22/10 | Crystal structure of the non-neutralizing HIV antibody 13H11 Fab fragment with a gp41 MPER-derived peptide in a helical conformation | MUS MUSCULUS,HOMO SAPIENS; SYNTHETIC CONSTRUCT | mus musculus,homo sapiens | mus musculus,homo sapiens | human immunodeficiency virus 1 | Nicely, N.I., Dennison, S.M., Kelsoe, G., Liao, H.-X., Alam, S.M., Haynes, B.F. | 2.2 | X-RAY DIFFRACTION | 0.253 | 0.181 | false | true | IGHV9 | IGKV8 | Kappa | null | null | null | null | null |
7jxd | C | D | 0 | null | null | null | null | IMMUNE SYSTEM | 08/27/20 | Mapping neutralizing and immunodominant sites on the SARS-CoV-2 spike receptor-binding domain by structure-guided high-resolution serology | HOMO SAPIENS | homo sapiens | homo sapiens | null | Park, Y.J., Tortorici, M.A., Walls, A.C., Czudnochowski, N., Seattle Structural Genomics Center for Infectious Disease (SSGCID), Snell, G., Veesler, D. | 2.5 | X-RAY DIFFRACTION | 0.259 | 0.203 | false | true | IGHV3 | IGLV6 | Lambda | null | null | null | null | null |
5hhv | H | L | 0 | A | protein | null | interleukin-17a | IMMUNE SYSTEM/INHIBITOR | 01/11/16 | Inhibiting complex IL-17A and IL-17RA interactions with a linear peptide | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | homo sapiens | Liu, S. | 2.2 | X-RAY DIFFRACTION | 0.236 | 0.198 | false | true | IGHV3 | IGLV6 | Lambda | null | null | null | null | null |
7vqx | N | null | 0 | A | B | protein | protein | NA | NA | guanine nucleotide-binding protein g(s) subunit alphaisoforms short | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | STRUCTURAL PROTEIN | 10/21/21 | Cryo-EM structure of human vasoactive intestinal polypeptide receptor 2 (VIP2R) in complex with PACAP27 and Gs | BOS TAURUS; RATTUS NORVEGICUS; SYNTHETIC CONSTRUCT; HOMO SAPIENS; SYNTHETIC CONSTRUCT | synthetic construct | null | bos taurus | rattus norvegicus | Xu, Y.N., Feng, W.B., Zhou, Q.T., Liang, A.Y., Li, J., Dai, A.T., Zhao, F.H., Yan, J.H., Chen, C.W., Li, H., Zhao, L.H., Xia, T., Jiang, Y., Xu, H.E., Yang, D.H., Wang, M.W. | 2.74 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | null | null | null | null | null | null | null |
6d6t | J | I | 0 | B | protein | null | gamma-aminobutyric acid receptor subunit alpha-1,gamma-aminobutyric acid receptor subunit alpha-1 | TRANSPORT PROTEIN | 04/22/18 | Human GABA-A receptor alpha1-beta2-gamma2 subtype in complex with GABA and flumazenil, conformation B | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | Zhu, S., Noviello, C.M., Teng, J., Walsh Jr, R.M., Kim, J.J., Hibbs, R.E. | 3.8 | ELECTRON MICROSCOPY | null | null | false | false | IGHV14 | IGKV6 | Kappa | 0 | -11.206815 | Unknown | null | TBD |
7cwm | H | L | 0 | A | protein | null | spike glycoprotein | VIRAL PROTEIN | 08/29/20 | Complex of SARS-CoV-2 spike protein and Fab P17 with one RBD in open state and two RBD in closed state | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Wang, N., Wang, X. | 3.6 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
5wtt | H | L | 0 | P | peptide | null | epitope peptide of cyr61 | PROTEIN BINDING | 12/14/16 | Structure of the 093G9 Fab in complex with the epitope peptide | HOMO SAPIENS; MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | homo sapiens | homo sapiens | Zhong, C., Hu, K., Shen, J., Ding, J. | 2.7 | X-RAY DIFFRACTION | 0.274 | 0.222 | false | true | IGHV3 | IGKV1 | Kappa | 0 | -9.006821 | Unknown | null | TBD |
4jj5 | B | A | 0 | null | null | null | null | Immune System | 03/07/13 | CRYSTAL STRUCTURE OF THE Fab FRAGMENT OF 1C2, A MONOCLONAL ANTIBODY SPECIFIC for POLY-GLUTAMINE | MUS MUSCULUS | mus musculus | mus musculus | null | Klein, F.A.C., Zeder-Lutz, G., Cousido-Siah, A., Mitschler, A., Katz, A., Eberling, P., Mandel, J.L., Podjarny, A., Trottier, Y. | 2.445 | X-RAY DIFFRACTION | 0.283 | 0.239 | false | true | IGHV9 | IGLV3 | Lambda | null | null | null | null | null |
3j2z | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 01/28/13 | Electron Cryo-microscopy of Chikungunya VLP in complex with neutralizing antibody Fab m10 | MUS MUSCULUS | mus musculus | mus musculus | null | Sun, S., Xiang, Y., Rossmann, M.G. | 16.9 | ELECTRON MICROSCOPY | null | null | false | false | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
6h7o | C | null | 0 | A | protein | null | beta-1 adrenergic receptor | ELECTRON TRANSPORT | 07/31/18 | ACTIVATED TURKEY BETA1 ADRENOCEPTOR WITH BOUND WEAK PARTIAL AGONIST CYANOPINDOLOL AND NANOBODY Nb6B9 | ESCHERICHIA COLI (STRAIN K12); MELEAGRIS GALLOPAVO; LAMA GLAMA | lama glama | null | meleagris gallopavo | Warne, T., Edwards, P.C., Dore, A.S., Leslie, A.G.W., Tate, c.g. | 2.8 | X-RAY DIFFRACTION | 0.274 | 0.240 | false | true | IGHV1 | null | null | 0 | -13.443087 | Unknown | null | TBD |
5x8l | F | K | 0 | A | protein | null | programmed cell death 1 ligand 1 | IMMUNE SYSTEM | 03/03/17 | PD-L1 in complex with atezolizumab | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Heo, Y.S., Lee, H.T. | 3.1 | X-RAY DIFFRACTION | 0.256 | 0.208 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6um5 | K | L | 0 | I | protein | null | ch848 10.17 dt gp120 | VIRAL PROTEIN/immune system | 10/09/19 | Cryo-EM structure of HIV-1 neutralizing antibody DH270 UCA3 in complex with CH848 10.17DT Env | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Acharya, P., Henderson, R.C., Saunders, K.O., Haynes, B.F. | 4.2 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGLV2 | Lambda | null | null | null | null | null |
6mh2 | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 09/17/18 | Structure of Herceptin Fab without antigen | HOMO SAPIENS | homo sapiens | homo sapiens | null | Luthra, A., Langley, D.B., Christie, M., Christ, D. | 2.8 | X-RAY DIFFRACTION | 0.306 | 0.251 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6b0a | H | L | 0 | A | protein | null | 25 kda ookinete surface antigen | IMMUNE SYSTEM | 09/14/17 | Crystal structure of Pfs25 in complex with the transmission blocking antibody 1269 | HOMO SAPIENS; PLASMODIUM FALCIPARUM | homo sapiens | homo sapiens | plasmodium falciparum | Scally, S.W., McLeod, B., Bosch, A., King, C.R., Julien, J.P. | 2.5 | X-RAY DIFFRACTION | 0.249 | 0.217 | false | true | IGHV3 | IGKV3 | Kappa | 0 | -11.503031 | BLI | null | TBD |
4f2m | A | B | 0 | E | protein | null | spike protein | VIRAL PROTEIN/IMMUNE SYSTEM | 05/08/12 | Crystal structure of a TGEV coronavirus Spike fragment in complex with the TGEV neutralizing monoclonal antibody 1AF10 | TGEV VIRULENT PURDUE; MUS MUSCULUS | mus musculus | mus musculus | tgev virulent purdue | Reguera, J., Santiago, C., Mudgal, G., Ordono, D., Enjuanes, L., Casasnovas, J.M. | 3.0 | X-RAY DIFFRACTION | 0.251 | 0.216 | false | true | IGHV1 | IGKV5 | Kappa | null | null | null | null | null |
1c1e | H | L | 0 | H | Hapten | ENH | 1,7,8,9,10,10-HEXACHLORO-4-METHYL-4-AZA-TRICYCLO[5.2.1.0(2,6)]DEC-8-ENE-3,5-DIONE | IMMUNE SYSTEM | 07/22/99 | CRYSTAL STRUCTURE OF A DIELS-ALDERASE CATALYTIC ANTIBODY 1E9 IN COMPLEX WITH ITS HAPTEN | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Xu, J., Wilson, I.A. | 1.9 | X-RAY DIFFRACTION | 0.294 | 0.239 | false | false | IGHV9 | IGKV1 | Kappa | null | null | null | null | null |
4xcf | H | L | 0 | P | peptide | null | modified fragment of hiv-1 glycoprotein (gp41) includingthe mper region 671-683 | IMMUNE SYSTEM | 12/18/14 | Crystal structure of human 4E10 Fab in complex with its peptide epitope on HIV-1 gp41; crystals cryoprotected with phosphatidylcholine (03:0 PC) | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Irimia, A., Stanfield, R.L., Wilson, I.A. | 1.43 | X-RAY DIFFRACTION | 0.170 | 0.137 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
4plk | D | C | 0 | B | protein | null | capsid protein | VIRAL PROTEIN/IMMUNE SYSTEM | 05/18/14 | Hepatitis E Virus E2s domain (Genotype I) in complex with a neutralizing antibody 8G12 | HEPATITIS E VIRUS; MUS MUSCULUS | mus musculus | mus musculus | hepatitis e virus | Tang, X.H., Li, S.W., Sivaraman, J. | 4.0 | X-RAY DIFFRACTION | 0.296 | 0.264 | false | false | IGHV1 | IGKV12 | Kappa | null | null | null | null | null |
7d6i | B | C | 0 | A | protein | null | sars-cov-2 receptor binding domain | ANTIVIRAL PROTEIN,IMMUNE SYSTEM | 09/30/20 | A neutralizing MAb targeting receptor-binding-domain of SARS-CoV-2 | SEVERE ACUTE RESPIRATORY SYNDROME-RELATED CORONAVIRUS; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome-relatedcoronavirus | Shi, R., Qi, J.X., Gao, G.F., Yan, J.H. | 3.41 | X-RAY DIFFRACTION | 0.255 | 0.226 | false | true | IGHV3 | IGLV6 | Lambda | null | null | null | null | null |
6gwn | C | null | 0 | A | protein | null | plasminogen activator inhibitor 1 | HYDROLASE | 06/25/18 | Crystal Structure of Stabilized Active Plasminogen Activator Inhibitor-1 (PAI-1-W175F) in Complex with Two Inhibitory Nanobodies (VHH-2g-42, VHH-2w-64) | HOMO SAPIENS; VICUGNA PACOS | vicugna pacos | null | homo sapiens | Sillen, M., Weeks, S.D., Strelkov, S.V., Declerck, P.J. | 2.03 | X-RAY DIFFRACTION | 0.250 | 0.208 | false | true | IGHV1 | null | null | null | null | null | null | null |
7kqi | A | C | 0 | B | protein | null | hemagglutinin | IMMUNE SYSTEM/VIRAL PROTEIN | 11/16/20 | Antibodies that engage the hemagglutinin receptor-binding site of influenza B viruses | HOMO SAPIENS; INFLUENZA B VIRUS | homo sapiens | homo sapiens | influenza b virus | Bajic, G., Harrison, S.C. | 4.2 | X-RAY DIFFRACTION | 0.420 | 0.372 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6xob | M | N | 0 | B | protein | null | togavirin | Virus/Immune System | 07/06/20 | CryoEM structure of Eastern Equine Encephalitis (EEEV) VLP with Fab EEEV-143. | EASTERN EQUINE ENCEPHALITIS VIRUS; HOMO SAPIENS | homo sapiens | homo sapiens | eastern equine encephalitis virus | Binshtein, E., Crowe, J.E. | 8.5 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
7wk9 | c | d | 0 | C | protein | null | heavy chain of s3h3 fab | VIRAL PROTEIN | 01/08/22 | SARS-CoV-2 Omicron open state spike protein in complex with S3H3 Fab | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; MUS MUSCULUS | mus musculus | mus musculus | severe acute respiratory syndrome coronavirus2 | Hong, Q., Cong, Y. | 3.48 | ELECTRON MICROSCOPY | null | null | false | false | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
5viy | J | I | 0 | D | protein | null | envelope glycoprotein gp160 | VIRAL PROTEIN/IMMUNE SYSTEM | 04/17/17 | BG505 SOSIP.664 in complex with broadly neutralizing antibodies BG1 and 8ANC195 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Wang, H., Bjorkman, P.J. | 6.2 | ELECTRON MICROSCOPY | null | null | false | true | unknown | IGKV1 | Kappa | null | null | null | null | null |
4dw2 | H | L | 0 | U | protein | null | urokinase-type plasminogen activator | HYDROLASE/IMMUNE SYSTEM | 02/24/12 | The crystal structure of uPA in complex with the Fab fragment of mAb-112 | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | Jiang, L., Botkjaer, K.A., Andersen, L.M., Yuan, C., Andreasen, P.A., Huang, M. | 2.97 | X-RAY DIFFRACTION | 0.300 | 0.240 | false | false | IGHV5 | IGKV4 | Kappa | null | null | null | null | null |
6wju | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 04/14/20 | Fab Fragment of Anti-human LAG3 antibody (4A10) | MUS MUSCULUS | mus musculus | mus musculus | null | Agnihotri, P., Mishra, A.K., Mariuzza, R.A. | 3.1 | X-RAY DIFFRACTION | 0.287 | 0.228 | false | true | IGHV14 | IGKV2 | Kappa | null | null | null | null | null |
3mug | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 05/03/10 | Crystal structure of human Fab PG16, a broadly reactive and potent HIV-1 neutralizing antibody | HOMO SAPIENS | homo sapiens | homo sapiens | null | Pejchal, R., Walker, L.M., Burton, D.R., Wilson, I.A. | 2.49 | X-RAY DIFFRACTION | 0.248 | 0.207 | false | true | IGHV3 | IGLV2 | Lambda | null | null | null | null | null |
5k9k | H | L | 0 | F | protein | null | hemagglutinin | IMMUNE SYSTEM | 05/31/16 | Crystal structure of multidonor HV6-1-class broadly neutralizing Influenza A antibody 56.a.09 in complex with Hemagglutinin Hong Kong 1968. | HOMO SAPIENS; INFLUENZA A VIRUS (STRAIN A/HONG KONG/1/1968 H3N2) | homo sapiens | homo sapiens | influenza a virus (strain a/hong kong/1/1968h3n2) | Joyce, M.G., Thomas, P.V., Wheatley, A.K., McDermott, A.B., Mascola, J.R., Kwong, P.D. | 2.97 | X-RAY DIFFRACTION | 0.265 | 0.225 | false | true | IGHV6 | IGKV3 | Kappa | null | null | null | null | null |
6vrp | A | a | 0 | null | null | null | null | PROTEIN BINDING | 02/08/20 | Reverse Transcriptase Diabody with R83T Mutation | HOMO SAPIENS | homo sapiens | null | null | Chesterman, C., Arnold, E. | 1.6 | X-RAY DIFFRACTION | 0.183 | 0.146 | true | true | unknown | unknown | unknown | null | null | null | null | null |
7kgj | B | null | 0 | A | protein | null | spike glycoprotein | VIRAL PROTEIN | 10/16/20 | Crystal structure of synthetic nanobody complexes with SARS-CoV-2 receptor binding domain | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; SYNTHETIC CONSTRUCT | synthetic construct | null | severe acute respiratory syndrome coronavirus2 | Jiang, J., Ahmad, J., Natarajan, K., Boyd, L.F., Margulies, D.H. | 2.3 | X-RAY DIFFRACTION | 0.216 | 0.186 | false | true | IGHV1 | null | null | null | null | null | null | null |
7e8c | N | P | 0 | B | protein | null | spike glycoprotein | VIRAL PROTEIN | 03/01/21 | SARS-CoV-2 S-6P in complex with 9 Fabs | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Du, S., Xiao, J., Zhang, Z. | 3.16 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
4nhg | A | C | 0 | null | null | null | null | IMMUNE SYSTEM | 11/05/13 | Crystal Structure of 2G12 IgG Dimer | HOMO SAPIENS | homo sapiens | homo sapiens | null | Wu, Y., West, Jr., A.P., Kim, H.J., Thornton, M.E., Ward, A.B., Bjorkman, P.J. | 8.001 | X-RAY DIFFRACTION | 0.369 | 0.359 | false | true | unknown | IGKV1 | Kappa | null | null | null | null | null |
6qtl | G | null | 0 | D | Hapten | CFF | CAFFEINE | BIOSYNTHETIC PROTEIN | 04/10/19 | Caffeine recognizing nanobody | CAMELIDAE | camelidae | null | camelidae | Lesne, J., Guichou, J.F., Labesse, G., Cohen-Gonsaud, M. | 2.25 | X-RAY DIFFRACTION | 0.259 | 0.194 | false | true | IGHV1 | null | null | null | null | null | null | null |
7l7e | C | D | 0 | b | protein | null | unknown | VIRAL PROTEIN/IMMUNE SYSTEM | 12/28/20 | Crystal structure of SARS-CoV-2 spike RBD in complex with human monoclonal antibodies AZD8895 and AZD1061 | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Dong, J., Crowe, J.E. | 3.0 | X-RAY DIFFRACTION | 0.273 | 0.215 | false | true | IGHV3 | IGKV4 | Kappa | null | null | null | null | null |
6wwc | D | H | 0 | F | peptide | null | fusion peptide | IMMUNE SYSTEM/VIRAL PROTEIN | 05/09/20 | Vaccine-elicited mouse FP-targeting neutralizing antibody vFP16.02 with S48K mutation in light chain in complex with HIV fusion peptide (residue 512-519) | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | human immunodeficiency virus 1 | Xu, K., Wang, Y., Kwong, P.D. | 2.563 | X-RAY DIFFRACTION | 0.267 | 0.209 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
1hin | H | L | 0 | P | peptide | null | influenza hemagglutinin ha1 (strain x47)(residues 100-107) | IMMUNOGLOBULIN | 07/08/92 | STRUCTURAL EVIDENCE FOR INDUCED FIT AS A MECHANISM FOR ANTIBODY-ANTIGEN RECOGNITION | MUS MUSCULUS | mus musculus | mus musculus | null | Rini, J.M., Wilson, I.A. | 3.1 | X-RAY DIFFRACTION | unknown | 0.220 | false | true | IGHV5 | IGKV8 | Kappa | null | null | null | null | null |
6de7 | H | L | 0 | G | protein | null | envelope glycoprotein gp160 | IMMUNE SYSTEM | 05/11/18 | Crystal Structure at 4.3 A Resolution of Glycosylated HIV-1 Clade A BG505 SOSIP.664 Prefusion Env Trimer with Interdomain Stabilization 113C-429GCG in Complex with Broadly Neutralizing Antibodies PGT122 and 35O22 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Gorman, J., Kwong, P.D. | 4.123 | X-RAY DIFFRACTION | 0.258 | 0.249 | false | true | IGHV4 | unknown | unknown | null | null | null | null | null |
6oc7 | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 03/22/19 | HMP42 Fab in complex with Protein G | HOMO SAPIENS; STREPTOCOCCUS SP. GROUP G | homo sapiens | homo sapiens | null | Bernard, S.M., Wilson, I.A. | 1.296 | X-RAY DIFFRACTION | 0.184 | 0.168 | false | true | IGHV1 | IGLV3 | Lambda | null | null | null | null | null |
6bt3 | B | A | 0 | N | protein | null | major capsid protein l1 | VIRUS | 12/05/17 | High-Resolution Structure Analysis of Antibody V5 Conformational Epitope on Human Papillomavirus 16 | MUS MUSCULUS; HUMAN PAPILLOMAVIRUS TYPE 16 | mus musculus | mus musculus | human papillomavirus type 16 | Guan, J., Bywaters, S.M., Brendle, S.A., Ashley, R.E., Makhov, A.M., Conway, J.F., Christensen, N.D., Hafenstein, S. | 4.7 | ELECTRON MICROSCOPY | null | null | false | false | IGHV1 | IGKV8 | Kappa | null | null | null | null | null |
5m95 | D | null | 0 | C | protein | null | divalent metal cation transporter mnth | TRANSPORT PROTEIN | 10/31/16 | STAPHYLOCOCCUS CAPITIS DIVALENT METAL ION TRANSPORTER (DMT) IN COMPLEX WITH MANGANESE | LAMA GLAMA; STAPHYLOCOCCUS CAPITIS | lama glama | null | staphylococcus capitis | Ehrnstorfer, I.A., Geertsma, E.R., Pardon, E., Steyaert, J., Dutzler, R. | 3.4 | X-RAY DIFFRACTION | 0.292 | 0.252 | false | true | IGHV1 | null | null | null | null | null | null | null |
7laa | H | L | 0 | A | protein | null | spike glycoprotein | VIRAL PROTEIN, IMMUNE SYSTEM | 01/06/21 | Structure of SARS-CoV-2 S protein in complex with Receptor Binding Domain antibody DH1041 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Manne, K., Acharya, P. | 3.42 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGLV1 | Lambda | null | null | null | null | null |
2xzc | H | L | 0 | L | Hapten | XOP | 8-METHYL-8-AZABICYCLO[3.2.1]OCTAN-3-YL PHENYLPHOSPHONATE | IMMUNE SYSTEM | 11/24/10 | Crystal Structure of phosphonate-modified recombinant A.17 antibody FAB fragment | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Carletti, E., Nachon, F., Nicolet, Y., Masson, P., Kurkova, I., Smirnov, I., Friboulet, A., Tramontano, A., Gabibov, A. | 1.36 | X-RAY DIFFRACTION | 0.19137 | 0.16172 | false | true | IGHV4 | IGLV1 | Lambda | 0.000002 | -7.67 | ITC | 25 | 21896761 |
2bmk | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 03/14/05 | Fab fragment of PLP-dependent catalytic antibody 15A9 in complex with phosphopyridoxyl-D-alanine | MUS MUSCULUS | mus musculus | mus musculus | null | Pimpaneau, B.Golinelli-, Christen, P. | 2.3 | X-RAY DIFFRACTION | 0.2725 | 0.2097 | false | true | IGHV7 | IGKV4 | Kappa | 0.000002 | -7.666764 | Unknown | null | TBD |
3ngb | J | K | 0 | I | protein | null | envelope glycoprotein gp160 | VIRAL PROTEIN/IMMUNE SYSTEM | 06/11/10 | Crystal structure of broadly and potently neutralizing antibody VRC01 in complex with HIV-1 gp120 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Zhou, T., Kwong, P.D. | 2.68 | X-RAY DIFFRACTION | 0.256 | 0.197 | false | true | IGHV1 | IGKV3 | Kappa | 0 | -10.88 | SPR | 20 | 20616231 |
7kqy | F | null | 0 | null | null | null | null | IMMUNE SYSTEM | 11/18/20 | Crystal Structure and Characterization of Human Heavy-Chain only Antibodies reveals a novel, stable dimeric structure similar to Monoclonal Antibodies | HOMO SAPIENS | homo sapiens | null | null | Bahmanjah, S., Mieczkowski, C., Yu, Y., Baker, J., Raghunathan, G., Tomazela, D., Hsieh, M., Mccoy, M., Strickland, C., Fayadat-Dilman, L. | 2.913 | X-RAY DIFFRACTION | 0.260 | 0.207 | false | true | IGHV1 | null | null | null | null | null | null | null |
7f54 | N | null | 0 | A | B | protein | protein | NA | NA | isoform gnas-2 of guanine nucleotide-binding protein g(s)subunit alpha isoforms short | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | MEMBRANE PROTEIN | 06/21/21 | Cryo-EM structure of afamelanotide-MC4R-Gs_Nb35 complex | HOMO SAPIENS; SYNTHETIC CONSTRUCT; SYNTHETIC CONSTRUCT | synthetic construct | null | homo sapiens | homo sapiens | Zhang, H., Chen, L., Mao, C., Shen, Q., Yang, D., Shen, D., Qin, J. | 3 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | null | null | null | null | null | null | null |
6al4 | F | E | 0 | null | null | null | null | IMMUNE SYSTEM | 08/07/17 | CRYSTAL STRUCTURE OF ANTI-CD19 ANTIBODY B43 FAB | HOMO SAPIENS | homo sapiens | homo sapiens | null | Teplyakov, A., Obmolova, G., Gilliland, G.L. | 2.45 | X-RAY DIFFRACTION | 0.236 | 0.206 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
6u50 | C | null | 0 | null | null | null | null | IMMUNE SYSTEM | 08/26/19 | Anti-Sudan ebolavirus Nucleoprotein Single Domain Antibody Sudan B (SB) | LAMA GLAMA | lama glama | null | null | Taylor, A.B., Sherwood, L.J., Hart, P.J., Hayhurst, A. | 1.6 | X-RAY DIFFRACTION | 0.214 | 0.169 | false | true | unknown | unknown | unknown | null | null | null | null | null |
7l8p | H | L | 0 | A | protein | null | isoform 3 of integrin alpha-iib | CELL ADHESION | 12/31/20 | Integrin alphaIIbbeta3 in complex with sibrafiban | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | Lin, F.-Y., Springer, T.A. | 2.34995 | X-RAY DIFFRACTION | 0.245 | 0.204 | false | true | IGHV14 | IGKV14 | Kappa | null | null | null | null | null |
2htk | E | F | 0 | B | protein | null | h(+)/cl(-) exchange transporter clca | MEMBRANE PROTEIN | 07/26/06 | Structure of the Escherichia coli ClC chloride channel Y445A mutant and Fab complex | ESCHERICHIA COLI; MUS MUSCULUS | mus musculus | mus musculus | escherichia coli | Accardi, A., Lobet, S., Williams, C., Miller, C., Dutzler, R. | 3.41 | X-RAY DIFFRACTION | 0.276 | 0.266 | false | false | IGHV4 | IGKV4 | Kappa | null | null | null | null | null |
5gs1 | N | M | 0 | null | null | null | null | IMMUNE SYSTEM | 08/13/16 | Crystal structure of homo-specific diabody | HOMO SAPIENS | homo sapiens | homo sapiens | null | Kim, J.H., Song, D.H., Youn, S.J., Kim, J.W., Cho, G., Lee, H., Lee, J.O. | 2.0 | X-RAY DIFFRACTION | 0.286 | 0.267 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
7bnp | A | null | 0 | null | null | null | null | IMMUNE SYSTEM | 01/22/21 | Llama nanobody nb17 raised against GldL from Flavobacterium jonhsoniae | LAMA GLAMA | lama glama | null | null | Trinh, N.T., Cambillau, C., Leone, P. | 1.7 | X-RAY DIFFRACTION | 0.226 | 0.213 | false | true | IGHV1 | null | null | null | null | null | null | null |
7nrh | H | L | 0 | A | protein | null | envelope polyprotein | VIRUS LIKE PARTICLE | 03/03/21 | Hantaan virus glycoprotein (Gn) in complex with Fab fragment HTN-Gn1. | ORYCTOLAGUS CUNICULUS; HANTAAN ORTHOHANTAVIRUS | oryctolagus cuniculus | oryctolagus cuniculus | hantaan orthohantavirus | Stass, R., Rissanen, I., Bowden, T.A., Huiskonen, J.T. | 19 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
6k0y | A | B | 0 | C | protein | null | programmed cell death protein 1 | IMMUNE SYSTEM | 05/08/19 | Study of the interactions of a novel monoclonal antibody, mAb059c, with the hPD-1 receptor | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Liu, J.X., Wang, G.Q. | 1.7 | X-RAY DIFFRACTION | 0.214 | 0.171 | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
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