pdb stringlengths 4 4 | Hchain stringclasses 59
values | Lchain stringclasses 60
values | model int64 0 76 | antigen_chain stringclasses 386
values | antigen_type stringclasses 24
values | antigen_het_name stringclasses 240
values | antigen_name stringlengths 1 396 ⌀ | short_header stringclasses 448
values | date stringlengths 8 8 | compound stringlengths 4 243 | organism stringlengths 3 175 ⌀ | heavy_species stringclasses 121
values | light_species stringclasses 67
values | antigen_species stringclasses 937
values | authors stringlengths 6 762 | resolution stringlengths 1 8 | method stringclasses 10
values | r_free stringclasses 354
values | r_factor stringclasses 342
values | scfv bool 2
classes | engineered bool 2
classes | heavy_subclass stringclasses 14
values | light_subclass stringclasses 35
values | light_ctype stringclasses 3
values | affinity float64 0 0 ⌀ | delta_g float64 -16.91 -5.04 ⌀ | affinity_method stringclasses 11
values | temperature float64 4 37 ⌀ | pmid stringclasses 157
values |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
7jie | C | D | 0 | B | protein | null | vp1 | VIRAL PROTEIN | 07/23/20 | Structure of GII.4 P-domain in Complex with NORO-320 FAB | NOROVIRUS HU/GII.4/SYDNEY/NSW0514/2012/AU; HOMO SAPIENS | homo sapiens | homo sapiens | norovirus hu/gii.4/sydney/nsw0514/2012/au | Salmen, W., Hu, L., Prasad, B. | 2.254 | X-RAY DIFFRACTION | 0.225 | 0.181 | false | true | IGHV1 | IGKV2 | Kappa | null | null | null | null | null |
5hdo | A | null | 0 | null | null | null | null | IMMUNE SYSTEM | 01/05/16 | Crystal structure of a nanobody raised against urokinase-type plasminogen activator | CAMELUS DROMEDARIUS | camelus dromedarius | null | null | Kromann-Hansen, T. | 2.16 | X-RAY DIFFRACTION | 0.218 | 0.177 | false | true | IGHV1 | null | null | null | null | null | null | null |
7p5y | K | null | 0 | E | protein | null | volume-regulated anion channel subunit lrrc8a | MEMBRANE PROTEIN | 07/15/21 | Structure of homomeric LRRC8A Volume-Regulated Anion Channel in complex with synthetic nanobody Sb3 | MUS MUSCULUS; SYNTHETIC CONSTRUCT | synthetic construct | null | mus musculus | Deneka, D., Rutz, S., Sawicka, M. | 3.29 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
3qeh | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 01/20/11 | Crystal structure of human N12-i15, an ADCC and non-neutralizing anti-HIV-1 Env antibody | HOMO SAPIENS | homo sapiens | homo sapiens | null | Guan, Y., DeVico, A.L., Lewis, G.K., Pazgier, M. | 2.59 | X-RAY DIFFRACTION | 0.254 | 0.216 | false | false | IGHV1 | IGKV2 | Kappa | null | null | null | null | null |
7s0b | C | D | 0 | E | protein | null | spike protein s1 | VIRAL PROTEIN/IMMUNE SYSTEM | 08/30/21 | Structure of the SARS-CoV-2 RBD in complex with neutralizing antibody N-612-056 | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Tanaka, S., Barnes, C.O., Bjorkman, P.J. | 2.9 | X-RAY DIFFRACTION | 0.260 | 0.215 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
7tfo | P | Q | 0 | C | protein | null | envelope glycoprotein bg505 sosip.664 - gp120 | VIRAL PROTEIN/IMMUNE SYSTEM | 01/06/22 | Cryo-EM structure of HIV-1 Env trimer BG505 SOSIP.664 in complex with CD4bs antibody Ab1573 | HUMAN IMMUNODEFICIENCY VIRUS 1; MACACA MULATTA | macaca mulatta | macaca mulatta | human immunodeficiency virus 1 | Yang, Z., Bjorkman, P.J. | 4.1 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
6mw9 | C | D | 0 | B | protein | null | e2 | VIRUS/IMMUNE SYSTEM | 10/29/18 | CryoEM structure of chimeric Eastern Equine Encephalitis Virus with Fab of EEEV-3 antibody | EASTERN EQUINE ENCEPHALITIS VIRUS; MUS MUSCULUS | mus musculus | mus musculus | eastern equine encephalitis virus | Hasan, S.S., Sun, C., Kim, A.S., Watanabe, Y., Chen, C.L., Klose, T., Buda, G., Crispin, M., Diamond, M.S., Klimstra, W.B., Rossmann, M.G. | 7.3 | ELECTRON MICROSCOPY | null | null | false | false | IGHV9 | IGLV1 | Lambda | null | null | null | null | null |
3chn | A | L | 6 | null | null | null | null | IMMUNE SYSTEM | 03/10/08 | Solution structure of human secretory IgA1 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Bonner, A., Almogren, A., Furtado, P.B., Kerr, M.A., Perkins, S.J. | NOT | SOLUTION SCATTERING / HOMOLOGY MODEL | null | null | false | false | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
7dk6 | c | d | 0 | B | protein | null | the light chain of 2h2 fab | VIRAL PROTEIN | 11/23/20 | S-2H2-F2 structure, two RBDs are up and one RBD is down, each up RBD binds with a 2H2 Fab. | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; MUS MUSCULUS | mus musculus | mus musculus | severe acute respiratory syndrome coronavirus2 | Cong, Y., Wang, Y.F. | 4.3 | ELECTRON MICROSCOPY | null | null | false | false | IGHV2 | IGKV3 | Kappa | null | null | null | null | null |
1a4k | H | L | 0 | H | Hapten | FRA | [4-(4-ACETYLAMINO-PHENYL)-3,5-DIOXO-4-AZA-TRICYCLO[5.2.2.0 2,6]UNDEC-1-YLCARBAMOYLOXY]-ACETIC ACID | IMMUNOGLOBULIN | 01/30/98 | DIELS ALDER CATALYTIC ANTIBODY WITH TRANSITION STATE ANALOGUE | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Spiller, B.W., Romesburg, F.E., Schultz, P.G., Stevens, R.C. | 2.4 | X-RAY DIFFRACTION | 0.291 | 0.211 | false | true | IGHV9 | IGKV1 | Kappa | 0 | -10.91 | Other | 25 | 9506942 |
4k07 | null | I | 0 | null | null | null | null | IMMUNE SYSTEM | 04/03/13 | Crystal structure of the amyloid-forming immunoglobulin AL-103 cis-proline 95 mutant | HOMO SAPIENS | null | homo sapiens | null | Thompson, J.R., Berkholz, D.S., Mahlum, E.W., Ramirez-Alvarado, M. | 2.83 | X-RAY DIFFRACTION | 0.236 | 0.202 | false | true | null | IGKV1 | Kappa | null | null | null | null | null |
7n65 | C | D | 0 | A | protein | null | envelope glycoprotein gp41 | VIRAL PROTEIN/IMMUNE SYSTEM | 06/07/21 | Complex structure of HIV superinfection Fab QA013.2 and BG505.SOSIP.664 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Mangala Prasad, V., Shipley, M.M., Overbaugh, J.M., Lee, K.K. | 4.15 | ELECTRON MICROSCOPY | null | null | false | true | unknown | unknown | unknown | null | null | null | null | null |
5mx3 | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 01/20/17 | Structure of DC8E8 Fab crystallized at pH 8.5 | MUS MUSCULUS | mus musculus | mus musculus | null | Skrabana, R., Novak, M., Cehlar, O., Kontsekova, E. | 2.98 | X-RAY DIFFRACTION | 0.256 | 0.219 | false | false | IGHV1 | IGKV8 | Kappa | null | null | null | null | null |
7mu4 | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 05/14/21 | Crystal Structure of HPV L1-directed D24.M01Fab | HOMO SAPIENS | homo sapiens | homo sapiens | null | Singh, S., Pancera, M. | 1.83 | X-RAY DIFFRACTION | 0.211 | 0.174 | false | true | IGHV2 | IGLV1 | Lambda | null | null | null | null | null |
7rai | J | N | 0 | E | protein | null | envelope glycoprotein gp160 | IMMUNE SYSTEM | 07/01/21 | Cryo-EM structure of M4008_N1 Fab in complex with BG505 DS-SOSIP.664 Env trimer | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Chan, K.-W., Kong, X.P. | 3.24 | ELECTRON MICROSCOPY | null | null | false | true | unknown | unknown | unknown | null | null | null | null | null |
7a17 | D | null | 0 | C | protein | null | isoform 2 of synaptojanin-1 | HYDROLASE | 08/12/20 | Crystal structure of the 5-phosphatase domain of Synaptojanin1 bound to its substrate diC8-PI(3,4,5)P3 in complex with a nanobody | HOMO SAPIENS; LAMA GLAMA | lama glama | null | homo sapiens | Paesmans, J., Galicia, C., Martin, E., Versees, W. | 2.73 | X-RAY DIFFRACTION | 0.257 | 0.196 | false | true | IGHV1 | null | null | null | null | null | null | null |
6gkd | P | null | 0 | O | protein | null | cystic fibrosis transmembrane conductance regulator | HYDROLASE | 05/18/18 | human NBD1 of CFTR in complex with nanobodies D12 and G3a | HOMO SAPIENS; LAMA GLAMA | lama glama | null | homo sapiens | Sigoillot, M., Overtus, M., Grodecka, M., Scholl, D., Garcia-Pino, A., Laeremans, T., He, L., Pardon, E., Hildebrandt, E., Urbatsch, I., Steyaert, J., Riordan, J.R., Govaerts, C. | 2.99 | X-RAY DIFFRACTION | 0.235 | 0.204 | false | true | IGHV1 | null | null | null | null | null | null | null |
6o25 | I | J | 0 | L | C | peptide | protein | NA | NA | circumsporozoite protein | anti-kappa vhh domain | IMMUNE SYSTEM | 02/22/19 | Crystal structure of 3945 Fab in complex with circumsporozoite protein NANP3 and anti-Kappa VHH domain | HOMO SAPIENS; LAMA GLAMA; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | plasmodium falciparum | lama glama | Scally, S.W., Bosch, A., Prieto, K., Murugan, R., Wardemann, H., Julien, J.P. | 2.9 | X-RAY DIFFRACTION | 0.268 | 0.215 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
1lo3 | Y | X | 0 | Y | Hapten | AN1 | 3-(10-METHYL-ANTHRACEN-9-YL)-PROPIONIC ACID | IMMUNE SYSTEM | 05/06/02 | Retro-Diels-Alderase Catalytic Antibody: Product Analogue | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Hugot, M., Reymond, J.L., Baumann, U. | 2.3 | X-RAY DIFFRACTION | 0.259 | 0.208 | false | false | IGHV5 | IGKV1 | Kappa | null | null | null | null | null |
7vsw | N | M | 0 | null | null | null | null | BIOSYNTHETIC PROTEIN | 10/27/21 | Crystal structure of a Fab-like fragment of anti-mesothelin antibody | HOMO SAPIENS | homo sapiens | homo sapiens | null | Yang, Z., Ying, T. | 3.0 | X-RAY DIFFRACTION | 0.253 | 0.217 | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
4jlr | H | L | 0 | S | protein | null | rsv_1isea designed scaffold | IMMUNE SYSTEM | 03/12/13 | Crystal structure of a designed Respiratory Syncytial Virus Immunogen in complex with Motavizumab | null | null | null | null | Rupert, P.B., Correia, B., Schief, W., Strong, R.K. | 2.71 | X-RAY DIFFRACTION | 0.249 | 0.191 | false | true | IGHV2 | IGKV1 | Kappa | 0 | -14.357753 | SPR | null | TBD |
6phb | D | C | 0 | I | protein | null | 25 kda ookinete surface antigen | IMMUNE SYSTEM | 06/25/19 | Pfs25 in complex with the human transmission blocking antibody 2530 | PLASMODIUM FALCIPARUM; HOMO SAPIENS | homo sapiens | homo sapiens | plasmodium falciparum | McLeod, B.R., Julien, J.P. | 2.0 | X-RAY DIFFRACTION | 0.209 | 0.177 | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
3ejy | C | D | 0 | A | protein | null | h(+)/cl(-) exchange transporter clca | IMMUNE SYSTEM/PROTON TRANSPORT | 09/18/08 | Structure of E203H mutant of E.coli Cl-/H+ antiporter, CLC-ec1 | ESCHERICHIA COLI; MUS MUSCULUS | mus musculus | mus musculus | escherichia coli | Lim, H.-H., Miller, C. | 3.2 | X-RAY DIFFRACTION | 0.279 | 0.244 | false | false | IGHV4 | IGKV4 | Kappa | null | null | null | null | null |
6niy | N | null | 0 | A | B | protein | protein | NA | NA | guanine nucleotide-binding protein g(s) subunit alphaisoforms short | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | MEMBRANE PROTEIN | 01/02/19 | A high-resolution cryo-electron microscopy structure of a calcitonin receptor-heterotrimeric Gs protein complex | HOMO SAPIENS; LAMA GLAMA; SYNTHETIC CONSTRUCT | lama glama | null | homo sapiens | homo sapiens | dal Maso, E., Glukhova, A., Zhu, Y., Garcia-Nafria, J., Tate, C.G., Atanasio, S., Reynolds, C.A., Ramirez-Aportela, E., Carazo, J.-M., Hick, C.A., Furness, S.G.B., Hay, D.L., Liang, Y.-L., Miller, L.J., Christopoulos, A., Wang, M.-W., Wootten, D., Sexton, P.M. | 3.34 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | null | null | null | null | null | null | null |
6opo | O | K | 0 | J | protein | null | envelope glycoprotein gp160 | VIRAL PROTEIN/Immune System | 04/25/19 | Symmetric model of CD4- and 17-bound B41 HIV-1 Env SOSIP in complex with DDM | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Ozorowski, G., Torres, J.L., Ward, A.B. | 3.5 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
1tqb | B | C | 0 | A | protein | null | prion protein | UNKNOWN FUNCTION/IMMUNE SYSTEM | 06/17/04 | Ovine recombinant PrP(114-234), VRQ variant in complex with the Fab of the VRQ14 antibody | OVIS ARIES; MUS MUSCULUS | mus musculus | mus musculus | ovis aries | Eghiaian, F., Grosclaude, J., Debey, P., Doublet, B., Treguer, E., Rezaei, H., Knossow, M. | 2.55 | X-RAY DIFFRACTION | 0.268 | 0.214 | false | true | IGHV9 | IGKV1 | Kappa | null | null | null | null | null |
4tqe | H | L | 0 | A | peptide | null | microtubule-associated protein tau | IMMUNE SYSTEM | 06/11/14 | Structure of tau peptide in complex with Tau5 antibody Fab fragment | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | homo sapiens | Cehlar, O., Skrabana, R., Novak, M. | 1.6 | X-RAY DIFFRACTION | 0.197 | 0.151 | false | false | IGHV14 | IGKV1 | Kappa | null | null | null | null | null |
4yhn | F | L | 0 | null | null | null | null | IMMUNE SYSTEM | 02/27/15 | Dabigatran Reversal Agent | HOMO SAPIENS | homo sapiens | homo sapiens | null | Schiele, F., Nar, H. | 2.31 | X-RAY DIFFRACTION | 0.220 | 0.182 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
2j4w | H | L | 0 | D | peptide | null | apical membrane antigen 1 | IMMUNE SYSTEM | 09/07/06 | Structure of a Plasmodium vivax apical membrane antigen 1-Fab F8.12. 18 complex | PLASMODIUM VIVAX; MUS MUSCULUS | mus musculus | mus musculus | plasmodium vivax | Igonet, S., Vulliez-Le Normand, B., Faure, G., Riottot, M.M., Kocken, C.H.M., Thomas, A.W., Bentley, G.A. | 2.5 | X-RAY DIFFRACTION | 0.241 | 0.187 | false | false | IGHV5 | IGKV4 | Kappa | 0 | -12.57 | SPR | null | 17229439 |
4hc1 | H | L | 0 | A | protein | null | mucosal addressin cell adhesion molecule 1 | IMMUNE SYSTEM | 09/28/12 | Crystal structure of a loop deleted mutant of human MAdCAM-1 D1D2 complexed with Fab 10G3 | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | Springer, T., Yu, Y., Zhu, J. | 2.871 | X-RAY DIFFRACTION | 0.253 | 0.200 | false | true | IGHV3 | IGKV14 | Kappa | null | null | null | null | null |
6m0f | H | L | 0 | A | protein | null | sodium-dependent dopamine transporter | MEMBRANE PROTEIN | 02/21/20 | X-ray structure of Drosophila dopamine transporter with subsiteB mutations (D121G/S426M) in substrate-free form | DROSOPHILA MELANOGASTER; MUS MUSCULUS | mus musculus | mus musculus | drosophila melanogaster | Shabareesh, P., Mallela, A.K., Joseph, D., Penmatsa, A. | 3.3 | X-RAY DIFFRACTION | 0.277 | 0.241 | false | true | IGHV5 | IGKV4 | Kappa | null | null | null | null | null |
6wgj | C | D | 0 | null | null | null | null | IMMUNE SYSTEM | 04/05/20 | Fab portion of dupilumab with Crystal Kappa design and no interchain disulfide | HOMO SAPIENS | homo sapiens | homo sapiens | null | Druzina, Z., Atwell, S., Pustilnik, A., Antonysamy, S., Ho, C., Lieu, R., Hendle, J., Benach, J., Wang, J. | 1.9 | X-RAY DIFFRACTION | 0.289 | 0.235 | false | true | IGHV3 | IGKV2 | Kappa | null | null | null | null | null |
5utz | H | L | 0 | D | protein | null | interleukin-2 | CYTOKINE/IMMUNE SYSTEM | 02/15/17 | Human IL-2/Fab complex | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Jude, K.M., Garcia, K.C. | 2.747 | X-RAY DIFFRACTION | 0.248 | 0.193 | false | true | IGHV4 | IGLV6 | Lambda | 0 | -11.904494 | SPR | null | TBD |
2q8b | H | L | 0 | A | protein | null | apical membrane antigen 1 | Immune System | 06/10/07 | Structure of the malaria antigen AMA1 in complex with a growth-inhibitory antibody | PLASMODIUM FALCIPARUM; MUS MUSCULUS | mus musculus | mus musculus | plasmodium falciparum | Gupta, A., Murphy, V.J., Anders, R.F., Batchelor, A.H. | 2.3 | X-RAY DIFFRACTION | 0.256 | 0.209 | false | false | IGHV14 | IGKV6 | Kappa | null | null | null | null | null |
5o05 | C | null | 0 | B | protein | null | capsid protein | VIRAL PROTEIN | 05/16/17 | GII.10 Vietnam 026 norovirus protruding domain in complex with Nanobody Nano-42 | VICUGNA PACOS; NORWALK VIRUS | vicugna pacos | null | norwalk virus | Koromyslova, A.D., Hansman, G.S. | 2.0 | X-RAY DIFFRACTION | 0.222 | 0.180 | false | true | IGHV1 | null | null | 0 | -12.403046 | ITC | null | TBD |
7a4y | A | null | 0 | null | null | null | null | DE NOVO PROTEIN | 08/20/20 | Crystal structure of the P5P6 coiled-coil in complex with nanobody Nb34. | LAMA GLAMA; SYNTHETIC CONSTRUCT | lama glama | null | null | Hadzi, S. | 2.157 | X-RAY DIFFRACTION | 0.229 | 0.196 | false | true | IGHV3 | null | null | null | null | null | null | null |
6x98 | H | L | 0 | A | protein | null | bg505 hiv-1 env gp120 | VIRAL PROTEIN/IMMUNE SYSTEM | 06/02/20 | Cryo-EM model of HIV-1 Env BG505 SOSIP.664 in complex with rabbit monoclonal antibody 11B fragment antigen binding variable domain | HUMAN IMMUNODEFICIENCY VIRUS 1; ORYCTOLAGUS CUNICULUS | oryctolagus cuniculus | oryctolagus cuniculus | human immunodeficiency virus 1 | Ozorowski, G., Cottrell, C.A., Ward, A.B. | 3.38 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
6ehy | A | a | 0 | null | null | null | null | IMMUNE SYSTEM | 09/15/17 | scFv AbVance: increasing our knowledge of antibody structural space to enable faster and better decision making in drug discovery | HOMO SAPIENS | homo sapiens | null | null | Hargreaves, D. | 2.25 | X-RAY DIFFRACTION | 0.285 | 0.228 | true | true | unknown | unknown | unknown | null | null | null | null | null |
2qtj | A | L | 6 | null | null | null | null | IMMUNE SYSTEM | 08/02/07 | Solution structure of human dimeric immunoglobulin A | HOMO SAPIENS | homo sapiens | homo sapiens | null | Bonner, A., Furtado, P.B., Almogren, A., Kerr, M.A., Perkins, S.J. | NOT | SOLUTION SCATTERING | null | null | false | false | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
5k59 | E | F | 0 | B | protein | null | uncharacterized leukocidin-like protein 1 | IMMUNE SYSTEM | 05/23/16 | Crystal structure of LukGH from Staphylococcus aureus in complex with a neutralising antibody | STAPHYLOCOCCUS AUREUS (STRAIN USA300); HOMO SAPIENS | homo sapiens | homo sapiens | staphylococcus aureus (strain usa300) | WELIN, M., LOGAN, D.T., BADARAU, A., MIRKINA, I., ZAUNER, G., DOLEZILKOVA, I., NAGY, E. | 2.84 | X-RAY DIFFRACTION | 0.237 | 0.197 | false | true | IGHV4 | IGKV1 | Kappa | 0 | -15.828042 | SPR | null | TBD |
7mfa | Q | R | 0 | null | null | null | null | IMMUNE SYSTEM | 04/08/21 | Crystal structure of antibody 10E8v4-P100fA+P100gA Fab | HOMO SAPIENS | homo sapiens | homo sapiens | null | Kwon, Y.D., Kwong, P.D. | 2.4 | X-RAY DIFFRACTION | 0.286 | 0.238 | false | true | IGHV3 | IGLV3 | Lambda | null | null | null | null | null |
6y54 | H | L | 0 | L | unknown | OAB | unknown | IMMUNE SYSTEM | 02/24/20 | Crystal structure of a Neisseria meningitidis serogroup A capsular oligosaccharide bound to a functional Fab | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Dello Iacono, L., Henriques, P., Adamo, R. | 2.67 | X-RAY DIFFRACTION | 0.267 | 0.210 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
5ywf | D | C | 0 | null | null | null | null | IMMUNE SYSTEM | 11/29/17 | Crystal structure of 2H4 Fab | MUS MUSCULUS | mus musculus | mus musculus | null | Qiu, X., Lei, Y., Yang, P., Gao, Q., Wang, N., Cao, L., Wang, X., Xu, Z.K., Rao, Z. | 2.206 | X-RAY DIFFRACTION | 0.262 | 0.216 | false | false | IGHV9 | IGKV3 | Kappa | null | null | null | null | null |
3ulv | D | C | 0 | A | protein | null | toll-like receptor 3 | IMMUNE SYSTEM | 11/11/11 | Structure of quaternary complex of human TLR3ecd with three Fabs (Form2) | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Luo, J., Gilliland, G.L., Obmolova, O., Malia, T., Teplyakov, A. | 3.522 | X-RAY DIFFRACTION | 0.253 | 0.231 | false | true | IGHV6 | IGLV3 | Lambda | null | null | null | null | null |
6sc8 | C | null | 0 | A | protein | null | e3 ubiquitin-protein ligase rnf31 | LIGASE | 07/23/19 | dAb3/HOIP-RBR-Ligand4 | HOMO SAPIENS; SYNTHETIC CONSTRUCT | synthetic construct | null | homo sapiens | Tsai, Y.-C.I., Johansson, H., House, D., Rittinger, K. | 2.106 | X-RAY DIFFRACTION | 0.261 | 0.219 | false | true | IGHV3 | null | null | null | null | null | null | null |
2kh2 | B | b | 15 | A | protein | null | interleukin-1 beta | Cytokine/IMMUNE SYSTEM | 03/23/09 | Solution structure of a scFv-IL-1B complex | HOMO SAPIENS; MUS MUSCULUS | mus musculus | null | homo sapiens | Wilkinson, I.C., Hall, C.J., Veverka, V., Muskett, F.W., Stephens, P.E., Taylor, R.J., Henry, A.J., Carr, M.D. | NOT | SOLUTION NMR | null | null | true | true | unknown | unknown | unknown | null | null | null | null | null |
4zg1 | E | null | 0 | null | null | null | null | PROTEIN BINDING | 04/22/15 | Crystal structure of a nanobody raised against KDM5b | LAMA GLAMA | lama glama | null | null | Wiuf, A., Kristensen, O., Gajhede, M. | 1.85 | X-RAY DIFFRACTION | 0.235 | 0.186 | false | true | IGHV1 | null | null | null | null | null | null | null |
7ej5 | I | M | 0 | B | protein | null | spike glycoprotein | VIRAL PROTEIN | 04/01/21 | Cryo-EM structure of SARS-CoV-2 spike in complex with a neutralizing antibody RBD-chAb-45 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Yang, T.J., Yu, P.Y., Wu, H.C., Hsu, S.T.D. | 3.5 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV6 | Kappa | null | null | null | null | null |
7jie | E | F | 0 | A | protein | null | vp1 | VIRAL PROTEIN | 07/23/20 | Structure of GII.4 P-domain in Complex with NORO-320 FAB | NOROVIRUS HU/GII.4/SYDNEY/NSW0514/2012/AU; HOMO SAPIENS | homo sapiens | homo sapiens | norovirus hu/gii.4/sydney/nsw0514/2012/au | Salmen, W., Hu, L., Prasad, B. | 2.254 | X-RAY DIFFRACTION | 0.225 | 0.181 | false | true | IGHV1 | IGKV2 | Kappa | null | null | null | null | null |
5x2m | H | L | 0 | A | protein | null | taste receptor, type 1, member 2a | SIGNALING PROTEIN/IMMUNE SYSTEM | 02/02/17 | Crystal structure of the medaka fish taste receptor T1r2a-T1r3 ligand binding domains in complex with L-glutamine | ORYZIAS LATIPES; MUS MUSCULUS | mus musculus | mus musculus | oryzias latipes | Nuemket, N., Yasui, N., Atsumi, N., Yamashita, A. | 2.206 | X-RAY DIFFRACTION | 0.227 | 0.173 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
7czs | J | N | 0 | C | protein | null | spike glycoprotein | VIRAL PROTEIN | 09/09/20 | S protein of SARS-CoV-2 in complex bound with P5A-1B8_3B | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Yan, R.H., Zhang, Y.Y., Li, Y.N., Zhou, Q. | 3.6 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6a76 | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 07/02/18 | Crystal structure of the Fab fragment of B5209B, a murine monoclonal antibody specific for the fifth immunoglobulin domain (Ig5) of human ROBO1 | MUS MUSCULUS | mus musculus | mus musculus | null | Mizohata, E., Nakayama, T., Kado, Y., Inoue, T. | 1.5 | X-RAY DIFFRACTION | 0.165 | 0.129 | false | true | IGHV5 | IGKV12 | Kappa | null | null | null | null | null |
3lrg | null | A | 0 | null | null | null | null | IMMUNE SYSTEM | 02/11/10 | Structure of anti-huntingtin VL domain | HOMO SAPIENS | null | homo sapiens | null | Schiefner, A., Chatwell, L., Skerra, A. | 2.05 | X-RAY DIFFRACTION | 0.197 | 0.170 | false | true | null | IGLV1 | Lambda | null | null | null | null | null |
4fqh | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 06/25/12 | Crystal Structure of Fab CR9114 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Dreyfus, C., Wilson, I.A. | 2.05 | X-RAY DIFFRACTION | 0.249 | 0.200 | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
3g6j | F | E | 0 | B | A | protein | protein | NA | NA | complement c3 alpha chain | complement c3 beta chain | IMMUNE SYSTEM | 02/06/09 | C3b in complex with a C3b specific Fab | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | homo sapiens | Wiesmann, C. | 3.1 | X-RAY DIFFRACTION | 0.282 | 0.214 | false | true | IGHV3 | IGKV1 | Kappa | 0 | -11.89 | SPR | 25 | 19196712 |
4f9p | C | c | 0 | A | protein | null | butyrophilin subfamily 3 member a1 | IMMUNE SYSTEM | 05/19/12 | Crystal Structure of the Human BTN3A1 Ectodomain in Complex with the 103.2 Single Chain Antibody | HOMO SAPIENS; MUS MUSCULUS | mus musculus | null | homo sapiens | Palakodeti, A., Sandstrom, A., Sundaresan, L., Harly, C., Nedellec, S., Olive, D., Scotet, E., Bonneville, M., Adams, E.J. | 3.519 | X-RAY DIFFRACTION | 0.408 | 0.373 | true | true | unknown | unknown | unknown | 0 | -10.673721 | SPR | null | TBD |
5g5r | B | null | 0 | A | protein | null | site-2 protease | HYDROLASE | 06/02/16 | CBS domain tandem of site-2 protease from Archaeoglobus fulgidus in complex with llama Nanobody - apo form | LAMA GLAMA; ARCHAEOGLOBUS FULGIDUS | lama glama | null | archaeoglobus fulgidus | Schacherl, M., Baumann, U. | 2.4 | X-RAY DIFFRACTION | 0.250 | 0.207 | false | true | IGHV1 | null | null | null | null | null | null | null |
3hi1 | H | L | 0 | G | protein | null | glycoprotein 120 | STRUCTURAL PROTEIN/Immune System | 05/18/09 | Structure of HIV-1 gp120 (core with V3) in Complex with CD4-Binding-Site Antibody F105 | HUMAN IMMUNODEFICIENCY VIRUS TYPE 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus type 1 | Kwon, Y.D., Chen, L., Zhou, T., Wu, X., O'Dell, S., Cavacini, L., Hessell, A.J., Pancera, M., Tang, M., Xu, L., Yang, Z., Zhang, M.-Y., Arthos, J., Burton, D.R., Dimitrov, D., Nabel, G.J., Posner, M., Sodroski, J., Wyatt, R., Mascola, J.R., Kwong, P.D. | 2.9 | X-RAY DIFFRACTION | 0.243 | 0.202 | false | false | IGHV4 | IGKV3 | Kappa | 0 | -10.84 | SPR | null | 19965434 |
7e5y | C | B | 0 | A | protein | null | spike protein s1 | VIRAL PROTEIN | 02/21/21 | Molecular basis for neutralizing antibody 2B11 targeting SARS-CoV-2 RBD | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Wu, H., Yu, F., Wang, Q.S., Zhou, H., Wang, W.W., Zhao, T., Pan, Y.B., Yang, X.M. | 3.59 | X-RAY DIFFRACTION | 0.277 | 0.232 | false | true | IGHV3 | IGLV1 | Lambda | null | null | null | null | null |
3g5z | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 02/05/09 | Antibodies Specifically Targeting a Locally Misfolded Region of Tumor Associated EGFR | MUS MUSCULUS | mus musculus | mus musculus | null | Garrett, T.P.J., Burgess, A.W. | 2.6 | X-RAY DIFFRACTION | 0.301 | 0.214 | false | true | IGHV3 | IGKV14 | Kappa | null | null | null | null | null |
7rdk | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 07/09/21 | Crystal structure of PCDN-16B, an anti-HIV antibody from the PCDN bnAb lineage (cysteinylated state) | HOMO SAPIENS | homo sapiens | homo sapiens | null | Omorodion, O., Wilson, I.A. | 2.46 | X-RAY DIFFRACTION | 0.253 | 0.208 | false | true | IGHV4 | IGKV3 | Kappa | null | null | null | null | null |
7phu | B | C | 0 | A | protein | null | reticulocyte-binding protein homolog 5 | IMMUNE SYSTEM | 08/18/21 | PfRH5 bound to monoclonal antibody R5.015 and R5.016 Fab fragments | PLASMODIUM FALCIPARUM (ISOLATE 3D7); HOMO SAPIENS | homo sapiens | homo sapiens | plasmodium falciparum (isolate 3d7) | Ragotte, R.J., Higgins, M.K. | 2.53 | X-RAY DIFFRACTION | 0.276 | 0.236 | false | true | IGHV1 | IGLV3 | Lambda | null | null | null | null | null |
7vne | W | null | 0 | C | protein | null | spike glycoprotein | VIRAL PROTEIN | 10/10/21 | Structure of the SARS-CoV-2 spike glycoprotein in complex with a human single domain antibody n3113.1 (UUU-state) | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | null | severe acute respiratory syndrome coronavirus2 | Yang, Z., Wang, Y., Kong, Y., Jin, Y., Wu, Y., Ying, T. | 3.5 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | null | null | null | null | null | null | null |
4ios | D | null | 0 | H | protein | null | bpp | VIRAL PROTEIN | 01/08/13 | Structure of phage TP901-1 RBP (ORF49) in complex with nanobody 11. | LACTOCOCCUS PHAGE TP901-1; LAMA GLAMA | lama glama | null | lactococcus phage tp901-1 | Desmyter, A., Farenc, C., Mahony, J., Spinelli, S., Bebeacua, C., Blangy, S., Veesler, D., van Sinderen, D., Cambillau, C. | 2.4 | X-RAY DIFFRACTION | 0.227 | 0.201 | false | true | IGHV1 | null | null | null | null | null | null | null |
2xqy | J | K | 0 | E | protein | null | envelope glycoprotein h | IMMUNE SYSTEM/VIRAL PROTEIN | 09/08/10 | Crystal structure of Pseudorabies core fragment of glycoprotein H in complex with Fab d6.3 | SUID HERPESVIRUS; MUS MUSCULUS | mus musculus | mus musculus | suid herpesvirus | Backovic, M., Dubois, R., Cockburn, J., Sharff, A., Vaney, M., Granzow, H., Klupp, B., Bricogne, G., Mettenleiter, T., Rey, F. | 2.05 | X-RAY DIFFRACTION | 0.2046 | 0.1878 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
5v8l | H | L | 0 | A | protein | null | gp120 | VIRAL PROTEIN/IMMUNE SYSTEM | 03/22/17 | BG505 SOSIP.664 trimer in complex with broadly neutralizing HIV antibodies 3BNC117 and PGT145 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Lee, J.H., Ward, A.B. | 4.3 | ELECTRON MICROSCOPY | null | null | false | true | unknown | IGKV1 | Kappa | null | null | null | null | null |
7eh3 | A | null | 1 | null | null | null | null | IMMUNE SYSTEM | 03/28/21 | Structure of Nanobody Nb23 in solution using NMR spectroscopy | LAMA GLAMA | lama glama | null | null | Percipalle, M., Hunashal, Y., Esposito, G., Fogolari, F. | NOT | SOLUTION NMR | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
4r7d | K | L | 0 | null | null | null | null | IMMUNE SYSTEM | 08/27/14 | Fab Hu 15C1 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Loyau, J., Didelot, G., Malinge, P., Ravn, U., Magistrelli, G., Depoisier, J.F., Kosco-Vilbois, M., Fischer, N., Thore, S., Rousseau, F. | 2.753 | X-RAY DIFFRACTION | 0.209 | 0.177 | false | true | IGHV4 | IGKV6 | Kappa | null | null | null | null | null |
5vh4 | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 04/12/17 | Crystal structure of Fab fragment of anti-TNFa antibody infliximab in an I-centered orthorhombic crystal form | MUS MUSCULUS, HOMO SAPIENS | mus musculus, homo sapiens | mus musculus, homo sapiens | null | Mayclin, S.J., Edwards, T.E., Lerch, T.F., Conlan, H., Sharpe, P. | 2.0 | X-RAY DIFFRACTION | 0.187 | 0.158 | false | true | IGHV6 | IGKV5 | Kappa | null | null | null | null | null |
6mu7 | H | L | 0 | G | protein | null | envelope glycoprotein gp160 | IMMUNE SYSTEM/INHIBITOR | 10/22/18 | Crystal Structure of HIV-1 BG505 SOSIP.664 Prefusion Env Trimer Bound to Small Molecule HIV-1 Entry Inhibitor BMS-818251 in Complex with Human Antibodies 3H109L and 35O22 at 3.1 Angstrom | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Lai, Y.-T., Kwong, P.D. | 2.501 | X-RAY DIFFRACTION | 0.261 | 0.223 | false | true | IGHV4 | unknown | unknown | null | null | null | null | null |
1mcd | null | B | 0 | P | peptide | null | peptide n-acetyl-d-phe-b-ala-l-his-d-pro-nh2 | IMMUNOGLOBULIN | 02/25/93 | PRINCIPLES AND PITFALLS IN DESIGNING SITE DIRECTED PEPTIDE LIGANDS | HOMO SAPIENS | null | homo sapiens | null | Edmundson, A.B., Harris, D.L., Fan, Z.-C., Guddat, L.W. | 2.7 | X-RAY DIFFRACTION | unknown | unknown | false | true | null | IGLV2 | Lambda | null | null | null | null | null |
6vl8 | A | B | 0 | E | Hapten | PEU | 2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80-HEPTACOSAOXADOOCTACONTAN-82-OL | IMMUNE SYSTEM | 01/23/20 | Anti-PEG antibody 6-3 Fab fragment in complex with PEG | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Nicely, N.I., Huckaby, J.T., Lai, S.K., Jacobs, T.M. | 2.42 | X-RAY DIFFRACTION | 0.240 | 0.185 | false | true | IGHV9 | IGKV8 | Kappa | null | null | null | null | null |
4xpb | H | L | 0 | null | null | null | null | tranport protein/inhibitor | 01/16/15 | X-ray structure of Drosophila dopamine transporter with subsiteB mutations (D121G/S426M) bound to cocaine | DROSOPHILA MELANOGASTER; MUS MUSCULUS | mus musculus | mus musculus | null | Aravind, P., Wang, K., Gouaux, E. | 3.05 | X-RAY DIFFRACTION | 0.269 | 0.244 | false | true | IGHV5 | IGKV4 | Kappa | null | null | null | null | null |
5sx4 | J | I | 0 | M | protein | null | epidermal growth factor receptor | TRANSFERASE/IMMUNE SYSTEM | 08/09/16 | Crystal Structure of panitumumab in complex with epidermal growth factor receptor domain 3. | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Sickmier, E.A., Kurzeja, R.J.M., Michelsen, K., Mukta, V., Yang, E., Tasker, A.S. | 2.8 | X-RAY DIFFRACTION | 0.266 | 0.223 | false | true | IGHV4 | IGKV1 | Kappa | 0 | -12.917374 | SPR | null | TBD |
7zf5 | G | I | 0 | A | protein | null | spike protein s1 | VIRAL PROTEIN | 04/01/22 | SARS-CoV-2 Omicron RBD in complex with Omi-12 and Beta-54 Fabs | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Zhou, D., Huo, J., Ren, J., Stuart, D.I. | 5.32 | X-RAY DIFFRACTION | 0.256 | 0.249 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
7t62 | B | b | 0 | null | null | null | null | IMMUNE SYSTEM | 12/13/21 | GPC2 HEP CT3 complex | HOMO SAPIENS; MUS MUSCULUS | mus musculus | null | null | Zhu, J., Cachau, R., De Val Alda, N., Li, N., Ho, M. | 21 | ELECTRON MICROSCOPY | null | null | true | true | unknown | unknown | unknown | null | null | null | null | null |
3ldb | C | B | 0 | A | protein | null | bifunctional arginine demethylase and lysyl-hydroxylasejmjd6 | IMMUNE SYSTEM | 01/12/10 | Structure of JMJD6 complexd with ALPHA-KETOGLUTARATE and Fab Fragment. | HOMO SAPIENS; CRICETULUS MIGRATORIUS | cricetulus migratorius | cricetulus migratorius | homo sapiens | Hong, X., Zang, J., White, J., Kappler, J.W., Wang, C., Zhang, G. | 2.7 | X-RAY DIFFRACTION | 0.285 | 0.250 | false | true | IGHV3 | IGKV8 | Kappa | null | null | null | null | null |
5n88 | H | null | 0 | E | protein | null | pc4 and sfrs1-interacting protein | IMMUNE SYSTEM | 02/23/17 | Crystal structure of antibody bound to viral protein | HOMO SAPIENS | homo sapiens | null | homo sapiens | Bao, L., Hannon, C., Cruz-Migoni, A., Ptchelkine, D., Sun, M.-y., Derveni, M., Bunjobpol, W., Chambers, J.S., Simmons, A., Phillips, S.E.V., Rabbitts, T.H. | 1.7 | X-RAY DIFFRACTION | 0.252 | 0.188 | false | true | IGHV3 | null | null | 0.000001 | -8.177812 | SPR | null | TBD |
5f7y | C | null | 0 | A | protein | null | adhesin binding fucosylated histo-blood group antigen | CELL ADHESION | 12/08/15 | Blood group antigen binding adhesin BabA of Helicobacter pylori strain 17875 in complex with blood group A type-1 hexasaccharide | HELICOBACTER PYLORI; LAMA GLAMA | lama glama | null | helicobacter pylori | Moonens, K., Gideonsson, P., Subedi, S., Romao, E., Oscarson, S., Muyldermans, S., Boren, T., Remaut, H. | 2.44 | X-RAY DIFFRACTION | 0.205 | 0.176 | false | true | IGHV1 | null | null | null | null | null | null | null |
3qxv | C | null | 0 | C | Hapten | MTX | METHOTREXATE | IMMUNE SYSTEM | 03/02/11 | Structure of an Anti-Methotrexate CDR1-4 Graft VHH Antibody in Complex with Methotrexate | LAMA GLAMA | lama glama | null | lama glama | Fanning, S.W., Horn, J.R. | 2.5 | X-RAY DIFFRACTION | 0.279 | 0.230 | false | true | IGHV1 | null | null | 0 | -11.45684 | Unknown | null | TBD |
4cdg | C | null | 0 | A | protein | null | bloom syndrome protein | null | 10/31/13 | Crystal structure of the Bloom's syndrome helicase BLM in complex with Nanobody | LAMA GLAMA; HOMO SAPIENS | lama glama | null | homo sapiens | Newman, J.A., Savitsky, P., Allerston, C.K., Pike, A.C.W., Pardon, E., Steyaert, J., Arrowsmith, C.H., Von Delft, F., Bountra, C., Edwards, A., Gileadi, O. | 2.794 | X-RAY DIFFRACTION | 0.2455 | 0.2056 | false | true | IGHV1 | null | null | null | null | null | null | null |
6oyz | E | null | 0 | A | protein | null | phospho-n-acetylmuramoyl-pentapeptide-transferase | MEMBRANE PROTEIN/TRANSFERASE | 05/15/19 | Crystal structure of MraY bound to capuramycin | LAMA GLAMA; AQUIFEX AEOLICUS (STRAIN VF5) | lama glama | null | aquifex aeolicus (strain vf5) | Mashalidis, E.H., Lee, S.Y. | 3.62 | X-RAY DIFFRACTION | 0.301 | 0.277 | false | true | IGHV1 | null | null | null | null | null | null | null |
7d4b | B | null | 0 | A | protein | null | tumor necrosis factor receptor superfamily member 9 | IMMUNE SYSTEM | 09/23/20 | Crystal structure of 4-1BB in complex with a VHH | HOMO SAPIENS; LAMA GLAMA | lama glama | null | homo sapiens | Wang, C. | 3.14 | X-RAY DIFFRACTION | 0.258 | 0.211 | false | true | IGHV1 | null | null | null | null | null | null | null |
5dfv | E | F | 0 | B | protein | null | cd81 antigen | IMMUNE SYSTEM | 08/27/15 | CRYSTAL STRUCTURE OF HUMAN CD81 LARGE EXTRACELLULAR LOOP IN COMPLEX WITH MURINE FAB FRAGMENT K04 | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | Harris, S.F., Wong, A., Kuglstatter, A. | 2.8 | X-RAY DIFFRACTION | 0.291 | 0.239 | false | false | IGHV1 | IGKV3 | Kappa | 0 | -12.688875 | SPR | null | TBD |
4tyu | B | null | 0 | null | null | null | null | IMMUNE SYSTEM | 07/09/14 | Homodimeric Single Domain Antibody (sdAb) against Staphylococcal enterotoxin B (SEB) | LAMA GLAMA | lama glama | null | null | Legler, P.M. | 2.13 | X-RAY DIFFRACTION | 0.263 | 0.239 | false | true | IGHV1 | null | null | null | null | null | null | null |
7s8o | E | e | 0 | B | C | protein | protein | NA | NA | guanine nucleotide-binding protein g(i) subunit alpha-1 | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | SIGNALING PROTEIN | 09/18/21 | CryoEM structure of Gi-coupled MRGPRX2 with small molecule agonist (R)-Zinc-3573 | ESCHERICHIA COLI; HOMO SAPIENS; MUS MUSCULUS | mus musculus | null | homo sapiens | homo sapiens | Cao, C., Fay, J.F., Gumpper, R.H., Roth, B.L. | 2.58 | ELECTRON MICROSCOPY | null | null | true | true | unknown | unknown | unknown | null | null | null | null | null |
3w9d | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 04/03/13 | Structure of Human Monoclonal Antibody E317 Fab | HOMO SAPIENS | homo sapiens | homo sapiens | null | Lee, C.C., Lin, L.L., Wang, A.H.J. | 2.32 | X-RAY DIFFRACTION | 0.259 | 0.190 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
7v61 | H | K | 0 | B | protein | null | angiotensin-converting enzyme 2 | MEMBRANE PROTEIN | 08/18/21 | ACE2 -Targeting Monoclonal Antibody as Potent and Broad-Spectrum Coronavirus Blocker | Homo sapiens; Severe acute respiratory syndrome coronavirus 2 | severe acute respiratory syndrome coronavirus2 | severe acute respiratory syndrome coronavirus2 | homo sapiens | Yan, R.H., Zhang, Y.Y., Li, Y.N., Zhou, Q. | 3.2 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV5 | Kappa | null | null | null | null | null |
5ken | C | D | 0 | B | protein | null | ebola surface glycoprotein, gp2 | VIRAL PROTEIN/IMMUNE SYSTEM | 06/09/16 | EBOV GP in complex with variable Fab domains of IgGs c4G7 and c13C6 | HOMO SAPIENS; ZAIRE EBOLAVIRUS (STRAIN MAYINGA-76); ZAIRE EBOLAVIRUS | homo sapiens | homo sapiens | zaire ebolavirus (strain mayinga-76) | Pallesen, J., Murin, C.D., de Val, N., Cottrell, C.A., Hastie, K.M., Turner, H.L., Fusco, M.L., Flyak, A.I., Zeitlin, L., Crowe Jr., J.E., Andersen, K.G., Saphire, E.O., Ward, A.B. | 4.3 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV12 | Kappa | null | null | null | null | null |
6tnp | K | J | 0 | null | null | null | null | IMMUNE SYSTEM | 12/09/19 | Crystal structure of the ScFv-5E5 in complex with a Tn glycopeptide | MUS MUSCULUS | mus musculus | mus musculus | null | Macias-Leon, J., Corzana, F., Hurtado-Guerrero, R. | 3.0 | X-RAY DIFFRACTION | 0.251 | 0.203 | false | true | IGHV1 | IGKV8 | Kappa | null | null | null | null | null |
7st8 | H | L | 0 | S | peptide | null | astacin-like metalloendopeptidase | IMMUNE SYSTEM | 11/12/21 | Crystal structure of 7H2.2 Fab in complex with SAS1B C-terminal region | MUS MUSCULUS; HOMO SAPIENS | mus musculus | mus musculus | homo sapiens | Legg, M.S.G., Evans, S.V. | 2.75 | X-RAY DIFFRACTION | 0.270 | 0.231 | false | true | IGHV8 | IGKV3 | Kappa | null | null | null | null | null |
4o4y | H | L | 0 | A | peptide | null | ides hinge peptide | IMMUNE SYSTEM | 12/19/13 | Crystal structure of the anti-hinge rabbit antibody 2095-2 in complex with IDES hinge peptide | ORYCTOLAGUS CUNICULUS, HOMO SAPIENS; SYNTHETIC CONSTRUCT | oryctolagus cuniculus, homo sapiens | oryctolagus cuniculus, homo sapiens | homo sapiens | Malia, T.J., Teplyakov, A., Luo, J., Gilliland, G.L. | 1.85 | X-RAY DIFFRACTION | 0.237 | 0.192 | false | true | IGHV1 | IGKV1 | Kappa | 0 | -10.654294 | Unknown | null | TBD |
4hjg | B | A | 0 | H | E | protein | protein | NA | NA | immunoglobulin g-binding protein a | protein l fragment | immune system | 10/12/12 | Meditope-enabled trastuzumab | HOMO SAPIENS; STAPHYLOCOCCUS AUREUS; FINEGOLDIA MAGNA | homo sapiens | homo sapiens | staphylococcus aureus | finegoldia magna | Donaldson, J.M., Zer, C., Avery, K.N., Bzymek, K.P., Horne, D.A., Williams, J.C. | 2.0 | X-RAY DIFFRACTION | 0.195 | 0.153 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
4w2q | E | null | 0 | F | protein | null | nucleoprotein | IMMUNE SYSTEM | 08/17/17 | Anti-Marburgvirus Nucleoprotein Single Domain Antibody C Complexed with Nucleoprotein C-terminal domain | LAMA GLAMA; LAKE VICTORIA MARBURGVIRUS | lama glama | null | lake victoria marburgvirus | Taylor, A.B., Garza, J.A. | 2.7 | X-RAY DIFFRACTION | 0.274 | 0.220 | false | true | IGHV1 | null | null | null | null | null | null | null |
7eh3 | A | null | 7 | null | null | null | null | IMMUNE SYSTEM | 03/28/21 | Structure of Nanobody Nb23 in solution using NMR spectroscopy | LAMA GLAMA | lama glama | null | null | Percipalle, M., Hunashal, Y., Esposito, G., Fogolari, F. | NOT | SOLUTION NMR | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
5aam | B | b | 0 | J | protein | null | envelope protein | null | 07/27/15 | Structure of a redesigned cross-reactive antibody to dengue virus with increased in vivo potency | MUS MUSCULUS; DENGUE VIRUS | mus musculus | null | dengue virus | Wong, Y.H., Robinson, L.N., Lescar, J., Sasisekharan, R. | 2.49 | X-RAY DIFFRACTION | 0.2698 | 0.2196 | true | true | unknown | unknown | unknown | 0 | -11.48723 | SPR | null | TBD |
4xnq | H | L | 0 | C | protein | null | influenza h5 ha head domain vietnam rdt mutations | Viral protein/Immune system | 01/15/15 | Antibody hemagglutinin Complexes | INFLUENZA A VIRUS; HOMO SAPIENS | homo sapiens | homo sapiens | influenza a virus | Spiller, B.W., Winarski, K.L. | 2.001 | X-RAY DIFFRACTION | 0.225 | 0.191 | false | true | IGHV4 | IGLV3 | Lambda | null | null | null | null | null |
3ubx | G | I | 0 | D | protein | null | antigen-presenting glycoprotein cd1d1 | IMMUNE SYSTEM | 10/25/11 | Crystal structure of the mouse CD1d-C20:2-aGalCer-L363 mAb Fab complex | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Yu, E.D., Zajonc, D.M. | 3.1 | X-RAY DIFFRACTION | 0.230 | 0.202 | false | false | IGHV9 | IGKV13 | Kappa | 0 | -10.366344 | Unknown | null | TBD |
6my4 | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 11/01/18 | Crystal structure of the dimeric bH1-Fab variant [HC-Y33W,HC-D98M,HC-G99M,LC-S30bR] | HOMO SAPIENS | homo sapiens | homo sapiens | null | Shi, R., Picard, M.-E., Manenda, M. | 1.69 | X-RAY DIFFRACTION | 0.230 | 0.189 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
2bx5 | null | M | 0 | null | null | null | null | ANTIBODY | 07/22/05 | Is FR1 the antibody's Achillies heel | ESCHERICHIA COLI | null | null | null | James, L.C. | 2.7 | X-RAY DIFFRACTION | 0.290 | 0.250 | false | true | null | IGKV1 | Kappa | null | null | null | null | null |
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