pdb stringlengths 4 4 | Hchain stringclasses 59
values | Lchain stringclasses 60
values | model int64 0 76 | antigen_chain stringclasses 386
values | antigen_type stringclasses 24
values | antigen_het_name stringclasses 240
values | antigen_name stringlengths 1 396 ⌀ | short_header stringclasses 448
values | date stringlengths 8 8 | compound stringlengths 4 243 | organism stringlengths 3 175 ⌀ | heavy_species stringclasses 121
values | light_species stringclasses 67
values | antigen_species stringclasses 937
values | authors stringlengths 6 762 | resolution stringlengths 1 8 | method stringclasses 10
values | r_free stringclasses 354
values | r_factor stringclasses 342
values | scfv bool 2
classes | engineered bool 2
classes | heavy_subclass stringclasses 14
values | light_subclass stringclasses 35
values | light_ctype stringclasses 3
values | affinity float64 0 0 ⌀ | delta_g float64 -16.91 -5.04 ⌀ | affinity_method stringclasses 11
values | temperature float64 4 37 ⌀ | pmid stringclasses 157
values |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
7a4d | H | null | 0 | L | peptide | null | aph coiled-coil | DE NOVO PROTEIN | 08/19/20 | Crystal structure of the APH coiled-coil in complex with nanobodies Nb28 and Nb30 | LAMA GLAMA; SYNTHETIC CONSTRUCT | lama glama | null | synthetic construct | Hadzi, S. | 2.694 | X-RAY DIFFRACTION | 0.223 | 0.177 | false | true | IGHV1 | null | null | null | null | null | null | null |
6ukt | C | null | 0 | A | protein | null | resistance to inhibitors of cholinesterase 8 homolog a (c.elegans) | SIGNALING PROTEIN | 10/05/19 | Cryo-EM structure of mammalian Ric-8A:Galpha(i):nanobody complex | RATTUS NORVEGICUS; LAMA GLAMA | lama glama | null | rattus norvegicus | Mou, T.C., Zhang, K., Johnston, J.D., Chiu, W., Sprang, S.R. | 3.87 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
5nml | J | null | 0 | null | null | null | null | IMMUNE SYSTEM | 04/06/17 | Nb36 Ser85Cys with Hg bound | LAMA GLAMA | lama glama | null | null | Hansen, S.B., Andersen, K.R., Laursen, N.S., Andersen, G.R. | 2.5 | X-RAY DIFFRACTION | 0.265 | 0.238 | false | true | IGHV1 | null | null | null | null | null | null | null |
4dvb | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 02/23/12 | The crystal structure of the Fab fragment of pro-uPA antibody mAb-112 | MUS MUSCULUS | mus musculus | mus musculus | null | Jiang, L., Botkjaer, K.A., Andersen, L.M., Yuan, C., Andreasen, P.A., Huang, M. | 1.93 | X-RAY DIFFRACTION | 0.259 | 0.223 | false | false | IGHV5 | IGKV4 | Kappa | null | null | null | null | null |
5t5n | G | F | 0 | E | protein | null | bestrophin-1 (best1) | MEMBRANE PROTEIN | 08/31/16 | Calcium-activated chloride channel bestrophin-1 (BEST1), triple mutant: I76A, F80A, F84A; in complex with an Fab antibody fragment, chloride, and calcium | GALLUS GALLUS; MUS MUSCULUS | mus musculus | mus musculus | gallus gallus | Long, S.B., Vaisey, G. | 3.1 | X-RAY DIFFRACTION | 0.243 | 0.218 | false | false | IGHV1 | IGKV12 | Kappa | null | null | null | null | null |
5mp3 | A | B | 0 | C | peptide | null | microtubule-associated protein | IMMUNE SYSTEM | 12/15/16 | Crystal structure of DC8E8 Fab in the complex with a 30-mer tau peptide at pH 6.5 | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | homo sapiens | Skrabana, R., Novak, M., Cehlar, O., Kontsekova, E. | 2.75 | X-RAY DIFFRACTION | 0.250 | 0.199 | false | false | IGHV1 | IGKV8 | Kappa | null | null | null | null | null |
4fq2 | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 06/24/12 | Crystal Structure of 10-1074 Fab | HOMO SAPIENS | homo sapiens | homo sapiens | null | Scharf, L., Bjorkman, P.J. | 1.9 | X-RAY DIFFRACTION | 0.223 | 0.187 | false | true | IGHV4 | unknown | unknown | null | null | null | null | null |
7lq7 | y | z | 0 | E | protein | null | spike protein s1 | IMMUNE SYSTEM | 02/13/21 | Crystal structure of SARS-CoV-2 receptor binding domain in complex with antibodies CV503 and COVA1-16 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Yuan, M., Zhu, X., Wilson, I.A. | 3.4 | X-RAY DIFFRACTION | 0.233 | 0.197 | false | false | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
5t1k | D | C | 0 | null | null | null | null | IMMUNE SYSTEM | 08/19/16 | Cetuximab Fab in complex with CQFDA(Ph)2STRRLKC | MUS MUSCULUS, HOMO SAPIENS; SYNTHETIC CONSTRUCT | mus musculus, homo sapiens | mus musculus, homo sapiens | null | Bzymek, K.P., Williams, J.C. | 2.48 | X-RAY DIFFRACTION | 0.213 | 0.160 | false | true | IGHV2 | IGKV5 | Kappa | 0.000001 | -8.56162 | Unknown | null | TBD |
5t3s | H | L | 0 | G | protein | null | envelope glycoprotein gp160 | IMMUNE SYSTEM | 08/26/16 | HIV gp140 trimer MD39-10MUTA in complex with Fabs PGT124 and 35022 | HOMO SAPIENS; HUMAN IMMUNODEFICIENCY VIRUS 1 | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Stanfield, R.L., Wilson, I.A. | 4.5 | X-RAY DIFFRACTION | 0.309 | 0.270 | false | true | IGHV4 | unknown | unknown | null | null | null | null | null |
7x7o | J | K | 0 | D | protein | null | spike protein s1 | VIRAL PROTEIN | 03/10/22 | SARS-CoV-2 spike RBD in complex with neutralizing antibody UT28K | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Ozawa, T., Tani, H., Anraku, Y., Kita, S., Igarashi, E., Saga, Y., Inasaki, N., Kawasuji, H., Yamada, H., Sasaki, S., Somekawa, M., Sasaki, J., Hayakawa, Y., Yamamoto, Y., Morinaga, Y., Kurosawa, N., Isobe, M., Fukuhara, H., Maenaka, K., Hashiguchi, T., Kishi, H., Kitajima, I., Saito, S., Niimi, H. | 3.75 | X-RAY DIFFRACTION | 0.336 | 0.303 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
6db7 | H | L | 0 | P | peptide | null | hiv-1 gp120 v3 peptide from mn strain | IMMUNE SYSTEM | 05/02/18 | Crystal structure of anti-HIV-1 V3 Fab 1334 in complex with a HIV-1 gp120 V3 peptide from MN strain | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Chan, K.-W., Kong, X.-P. | 2.213 | X-RAY DIFFRACTION | 0.260 | 0.213 | false | true | IGHV1 | IGLV3 | Lambda | null | null | null | null | null |
7mhy | O | P | 0 | A | protein | null | protein-cysteine n-palmitoyltransferase hhat | TRANSFERASE/IMMUNE SYSTEM | 04/16/21 | Human Hedgehog acyltransferase (HHAT) in complex with palmitoyl-CoA and two Fab antibody fragments | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | Long, S.B., Jiang, Y. | 2.7 | ELECTRON MICROSCOPY | null | null | false | true | IGHV9 | IGKV1 | Kappa | null | null | null | null | null |
7tyo | N | null | 0 | A | B | protein | protein | NA | NA | guanine nucleotide-binding protein g(s) subunit alphaisoforms short | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | MEMBRANE PROTEIN | 02/14/22 | Calcitonin receptor in complex with Gs and human calcitonin peptide | HOMO SAPIENS; LAMA GLAMA; SYNTHETIC CONSTRUCT | lama glama | null | homo sapiens | homo sapiens | Cao, J., Belousoff, M.J., Johnson, R.M., Wootten, D.L., Sexton, P.M. | 2.7 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | null | null | null | null | null | null | null |
7t3d | P | R | 0 | I | protein | null | hemagglutinin ha2 chain | Viral Protein/IMMUNE SYSTEM | 12/07/21 | CryoEM map of anchor 222-1C06 Fab and lateral patch 2B05 Fab binding H1 HA | INFLUENZA A VIRUS (A/CALIFORNIA/04/2009(H1N1)); HOMO SAPIENS | homo sapiens | homo sapiens | influenza a virus (a/california/04/2009(h1n1)) | Han, J., Ward, A.B. | 3.2 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
5m30 | F | null | 0 | C | protein | null | type vi secretion protein | SECRETION SYSTEM | 10/13/16 | Structure of TssK from T6SS EAEC in complex with nanobody nb18 | VICUGNA PACOS; ESCHERICHIA COLI | vicugna pacos | null | escherichia coli | Nguyen, V.S., Cambillau, C., Spinelli, C., Desmyter, A., Legrand, P., Cascales, E. | 2.6 | X-RAY DIFFRACTION | 0.226 | 0.207 | false | true | IGHV1 | null | null | null | null | null | null | null |
6ocd | D | null | 0 | C | protein | null | ricin a chain | TOXIN | 04/01/20 | Ricin A chain bound to VHH antibody V6D4 | RICINUS COMMUNIS; VICUGNA PACOS | vicugna pacos | null | ricinus communis | Rudolph, M.J. | 2.103 | X-RAY DIFFRACTION | 0.228 | 0.189 | false | true | IGHV1 | null | null | null | null | null | null | null |
6rbb | I | null | 0 | null | null | null | null | IMMUNE SYSTEM | 05/13/20 | CRYSTAL STRUCTURE OF the VhH-domain of anti-IL-17A antibody netakimab | LAMA GLAMA | lama glama | null | null | Kostareva, O.S., Kolyadenko, I.A., Ulitin, A.B., Ekimova, V.M., Evdokimov, S.R., Garber, M.B., Tishchenko, T.V., Gabdulkhakov, A.G. | 2.45 | X-RAY DIFFRACTION | 0.280 | 0.216 | false | true | IGHV1 | null | null | null | null | null | null | null |
6opp | H | L | 0 | A | protein | null | envelope glycoprotein gp160 | VIRAL PROTEIN/Immune System | 04/25/19 | Asymmetric model of CD4- and 17-bound B41 HIV-1 Env SOSIP in complex with DDM | HOMO SAPIENS; HUMAN IMMUNODEFICIENCY VIRUS 1 | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Ozorowski, G., Torres, J.L., Ward, A.B. | 3.7 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
6n7j | A | B | 0 | D | peptide | null | envelope glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 11/27/18 | BDBV223 Fab bound to synthetic peptide of Bundibugyo virus Glycoprotein Stalk | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | bundibugyo ebolavirus | King, L.B., West, B.R., Saphire, E.O. | 3.684 | X-RAY DIFFRACTION | 0.254 | 0.228 | false | true | IGHV4 | IGKV3 | Kappa | null | null | null | null | null |
3qrg | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 02/17/11 | Crystal structure of antiRSVF Fab B21m | HOMO SAPIENS | homo sapiens | homo sapiens | null | Luo, J., Tsui, P., Lewandowski, F., Spurlino, J., Vecchio, F.D. | 1.699 | X-RAY DIFFRACTION | 0.185 | 0.161 | false | true | IGHV2 | IGKV4 | Kappa | null | null | null | null | null |
7l7e | E | F | 0 | G | protein | null | spike protein s1 | VIRAL PROTEIN/IMMUNE SYSTEM | 12/28/20 | Crystal structure of SARS-CoV-2 spike RBD in complex with human monoclonal antibodies AZD8895 and AZD1061 | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Dong, J., Crowe, J.E. | 3.0 | X-RAY DIFFRACTION | 0.273 | 0.215 | false | true | IGHV3 | IGKV4 | Kappa | null | null | null | null | null |
7lmo | null | A | 0 | B | Hapten | NYO | (5~{R})-3-[2-[7-(diethylamino)-4-methyl-2-oxidanylidene-chromen-3-yl]ethyl]-7-(1~{H}-imidazol-4-ylcarbonyl)-1,3,7-triazaspiro[4.4]nonane-2,4-dione | IMMUNE SYSTEM | 02/05/21 | Structure of full-length human lambda-6A light chain JTO in complex with stabilizer 34 [3-(2-(7-(diethylamino)-4-methyl-2-oxo-2H-chromen-3-yl)ethyl)-7-(1H-imidazole-5-carbonyl)-1,3,7-triazaspiro[4.4]nonane-2,4-dione] | HOMO SAPIENS | null | homo sapiens | homo sapiens | Yan, N.L., Wilson, I.A., Kelly, J.W. | 1.99 | X-RAY DIFFRACTION | 0.225 | 0.176 | false | true | null | IGLV6 | Lambda | null | null | null | null | null |
7ej4 | I | M | 0 | B | protein | null | spike glycoprotein | VIRAL PROTEIN | 04/01/21 | Cryo-EM structure of SARS-CoV-2 spike in complex with a neutralizing antibody RBD-chAb-25 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Yang, T.J., Yu, P.Y., Wu, H.C., Hsu, S.T.D. | 3.6 | ELECTRON MICROSCOPY | null | null | false | true | IGHV5 | IGKV4 | Kappa | null | null | null | null | null |
1svz | a | A | 0 | C | peptide | null | epitope peptide corresponding to n-terminus ofhiv-2 protease | IMMUNE SYSTEM | 03/30/04 | Crystal structure of the single-chain Fv fragment 1696 in complex with the epitope peptide corresponding to N-terminus of HIV-2 protease | MUS MUSCULUS; SYNTHETIC CONSTRUCT | null | mus musculus | null | Rezacova, P., Brynda, J., Lescar, J., Bentley, G.A., Fabry, M., Horejsi, M., Sedlacek, J. | 1.89 | X-RAY DIFFRACTION | 0.239 | 0.196 | true | true | unknown | unknown | unknown | null | null | null | null | null |
4zxb | C | D | 0 | E | protein | null | insulin receptor | HORMONE RECEPTOR/IMMUNE SYSTEM | 05/20/15 | Structure of the human insulin receptor ectodomain, IRDeltabeta construct, in complex with four Fab molecules | MUS MUSCULUS; HOMO SAPIENS | mus musculus | mus musculus | homo sapiens | Croll, T., Smith, B.J., Margetts, M.B., Whittaker, J., Weiss, M.A., Ward, C.W., Lawrence, M.C. | 3.3 | X-RAY DIFFRACTION | 0.237 | 0.205 | false | true | IGHV1 | IGKV9 | Kappa | null | null | null | null | null |
5u5f | B | A | 0 | C | E | protein | protein | NA | NA | immunoglobulin g binding protein a | protein l | IMMUNE SYSTEM | 12/06/16 | MEDITOPE ENABLED TRASTUZUMAB I83E VARIANT IN COMPLEX WITH (Ac) CQFDA(PH)2STRRLRCGGSK | HOMO SAPIENS; FINEGOLDIA MAGNA; STAPHYLOCOCCUS AUREUS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | staphylococcus aureus | finegoldia magna | Bzymek, K.P., Avery, K.N., Zer, C., Williams, J.C. | 1.81 | X-RAY DIFFRACTION | 0.192 | 0.163 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
1mj7 | H | L | 0 | H | Hapten | HAL | N-{[2-({[1-(4-CARBOXYBUTANOYL)AMINO]-2-PHENYLETHYL}-HYDROXYPHOSPHINYL)OXY]ACETYL}-2-PHENYLETHYLAMINE | IMMUNE SYSTEM | 08/27/02 | Crystal Structure Of The Complex Of The Fab fragment of Esterolytic Antibody MS5-393 and A Transition-State Analog | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Ruzheinikov, S.N., Muranova, T.A., Sedelnikova, S.E., Partridge, L.J., Blackburn, G.M., Murray, I.A., Kakinuma, H., Takashi, N., Shimazaki, K., Sun, J., Nishi, Y., Rice, D.W. | 2.25 | X-RAY DIFFRACTION | 0.303 | 0.200 | false | true | IGHV1 | IGKV2 | Kappa | 0 | -11.387055 | Unknown | null | TBD |
7np1 | K | O | 0 | D | protein | null | spike protein s1 | VIRAL PROTEIN | 02/26/21 | Crystal Structure of the SARS-CoV-2 Receptor Binding Domain in Complex with Antibody ION-360 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Hall, G., Cowan, R., Carr, M. | 2.8 | X-RAY DIFFRACTION | 0.281 | 0.232 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
5vk2 | F | G | 0 | b | B | protein | protein | NA | NA | unknown | pre-glycoprotein polyprotein gp complex | VIRAL PROTEIN/Immune system | 04/20/17 | Structural basis for antibody-mediated neutralization of Lassa virus | LASSA VIRUS; LASSA VIRUS (STRAIN MOUSE/SIERRA LEONE/JOSIAH/1976); HOMO SAPIENS | homo sapiens | homo sapiens | lassa virus (strain mouse/sierraleone/josiah/1976) | lassa virus | Hastie, K.M., Zandonatti, M.A., Kleinfelter, L.M., Rowland, M.L., Rowland, M.M., Chandra, K., Branco, L.M., Robinson, J.E., Garry, R.F., Saphire, E.O. | 3.201 | X-RAY DIFFRACTION | 0.231 | 0.189 | false | true | IGHV3 | IGLV2 | Lambda | null | null | null | null | null |
6xsk | H | L | 0 | F | E | protein | protein | NA | NA | hemagglutinin ha2 chain | hemagglutinin ha1 chain | IMMUNE SYSTEM/Viral Protein | 07/15/20 | Cryo-EM structure of vaccine-elicited Rhesus VH6-1 antibody 789-203-3C12 in complex with stabilized SI06 (A/Solomon Islands/3/06) Influenza Hemagglutinin Trimer | MACACA MULATTA; INFLUENZA A VIRUS (A/SOLOMON ISLANDS/3/2006(H1N1)) | macaca mulatta | macaca mulatta | influenza a virus (a/solomonislands/3/2006(h1n1)) | influenza a virus (a/solomonislands/3/2006(h1n1)) | Cerutti, G., Gorman, J., Kwong, P.D., Shapiro, L. | 3.85 | ELECTRON MICROSCOPY | null | null | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
6p3s | P | Q | 0 | R | protein | null | hemagglutinin | IMMUNE SYSTEM/VIRAL PROTEIN | 05/27/20 | Crystal structure of human Fab H5.28 in complex with influenza A H5N1 Vietnam hemagglutinin head domain | HOMO SAPIENS; INFLUENZA A VIRUS (A/CHICKEN/VIETNAM/32/2004(H5N1)) | homo sapiens | homo sapiens | influenza a virus(a/chicken/vietnam/32/2004(h5n1)) | Dong, J., Crowe, J.E. | 4.0 | X-RAY DIFFRACTION | 0.326 | 0.281 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
4m7j | H | L | 0 | H | carbohydrate | KDA | polysaccharide | IMMUNE SYSTEM | 08/12/13 | Crystal structure of S25-26 in complex with Kdo(2.8)Kdo(2.4)Kdo trisaccharide | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Haji-Ghassemi, O., Evans, S.V., Muller-Loennies, S., Saldova, R., Muniyappa, M., Brade, L., Rudd, P.M., Harvey, D.J., Kosma, P., Brade, H. | 1.95 | X-RAY DIFFRACTION | 0.247 | 0.212 | false | false | IGHV2 | IGKV1 | Kappa | 0.000001 | -8.331915 | Unknown | null | TBD |
2ltq | C | B | 3 | A | protein | null | disulfide bond formation protein b | MEMBRANE PROTEIN, OXIDOREDUCTASE | 05/30/12 | High resolution structure of DsbB C41S by joint calculation with solid-state NMR and X-ray data | ESCHERICHIA COLI; MUS MUSCULUS | mus musculus | mus musculus | escherichia coli | Tang, M., Sperling, L.J., Schwieters, C.D., Nesbitt, A.E., Gennis, R.B., Rienstra, C.M. | NOT | SOLID-STATE NMR | null | null | false | false | IGHV5 | IGKV8 | Kappa | null | null | null | null | null |
6vep | I | J | 0 | K | protein | null | insulin receptor subunit alpha | HORMONE RECEPTOR/HORMONE/IMMUNE SYSTEM | 06/03/20 | Human insulin in complex with the human insulin microreceptor in turn in complex with Fv 83-7 | HOMO SAPIENS; MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | homo sapiens | Lawrence, M.C., Menting, J.G.T. | 2.9 | X-RAY DIFFRACTION | 0.225 | 0.193 | false | true | IGHV2 | IGKV8 | Kappa | null | null | null | null | null |
5fec | A | B | 0 | D | protein | null | 426c.tm4deltav1-3 gp120 | IMMUNE SYSTEM | 12/16/15 | Crystal structure of 3BNC60 Fab germline precursor in complex with 426c.TM4deltaV1-3 gp120 | HOMO SAPIENS; HUMAN IMMUNODEFICIENCY VIRUS 1 | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Scharf, L., Bjorkman, P.J. | 3.17 | X-RAY DIFFRACTION | 0.266 | 0.202 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
7rly | A | B | 0 | Q | peptide | null | peptide from circumsporozoite protein variant vk210 | ANTIMICROBIAL PROTEIN | 07/26/21 | Antibody 2F2 in complex with P. vivax CSP peptide DRAAGQPAGDRADGQPA | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | plasmodium vivax | Kucharska, I., Julien, J.P. | 2.67 | X-RAY DIFFRACTION | 0.227 | 0.185 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
1s5h | B | A | 0 | C | protein | null | voltage-gated potassium channel | MEMBRANE PROTEIN | 01/20/04 | Potassium Channel Kcsa-Fab Complex T75C mutant in K+ | STREPTOMYCES COELICOLOR, STREPTOMYCES LIVIDANS; MUS MUSCULUS | mus musculus | mus musculus | streptomyces coelicolor, streptomyces lividans | Mackinnon, R., Zhou, M. | 2.2 | X-RAY DIFFRACTION | 0.240 | 0.222 | false | false | IGHV1 | IGKV5 | Kappa | null | null | null | null | null |
6q23 | J | K | 0 | B | protein | null | neuraminidase | VIRAL PROTEIN,HYDROLASE/IMMUNE SYSTEM | 08/06/19 | Crystal structure of human 1G01 Fab in complex with influenza virus neuraminidase from A/California/04/2009 (H1N1) | INFLUENZA A VIRUS (A/CALIFORNIA/04/2009 (H1N1); HOMO SAPIENS | homo sapiens | homo sapiens | influenza a virus (a/california/04/2009 (h1n1) | Zhu, X., Wilson, I.A. | 3.27 | X-RAY DIFFRACTION | 0.241 | 0.196 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
3zks | D | null | 0 | A | protein | null | beta-secretase 2 | HYDROLASE/IMMUNE SYSTEM | 01/24/13 | BACE2 XAPERONE COMPLEX WITH INHIBITOR | HOMO SAPIENS; LAMA GLAMA | lama glama | null | homo sapiens | Banner, D.W., Kuglstatter, A., Benz, J., Stihle, M., Ruf, A. | 2.11 | X-RAY DIFFRACTION | 0.26041 | 0.20850 | false | true | IGHV3 | null | null | null | null | null | null | null |
3ifp | A | B | 0 | Q | peptide | null | amyloid beta a4 protein | IMMUNE SYSTEM | 07/24/09 | X-ray structure of amyloid beta peptide:antibody (Abeta1-7:12B4) complex | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | homo sapiens | Weis, W.I., Feinberg, H., Basi, G.S., Schenk, D. | 2.95 | X-RAY DIFFRACTION | 0.269 | 0.235 | false | true | IGHV8 | IGKV1 | Kappa | 0 | -10.38 | SPR | 25 | 19923222 |
3j2z | D | C | 0 | null | null | null | null | IMMUNE SYSTEM | 01/28/13 | Electron Cryo-microscopy of Chikungunya VLP in complex with neutralizing antibody Fab m10 | MUS MUSCULUS | mus musculus | mus musculus | null | Sun, S., Xiang, Y., Rossmann, M.G. | 16.9 | ELECTRON MICROSCOPY | null | null | false | false | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
3kym | H | G | 0 | null | null | null | null | IMMUNE SYSTEM | 12/06/09 | Crystal structure of Li33 IgG2 di-Fab | HOMO SAPIENS | homo sapiens | homo sapiens | null | Silvian, L.F., Pepinsky, R.B., Walus, L. | 2.62 | X-RAY DIFFRACTION | 0.339 | 0.259 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
6wju | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 04/14/20 | Fab Fragment of Anti-human LAG3 antibody (4A10) | MUS MUSCULUS | mus musculus | mus musculus | null | Agnihotri, P., Mishra, A.K., Mariuzza, R.A. | 3.1 | X-RAY DIFFRACTION | 0.287 | 0.228 | false | true | IGHV14 | IGKV2 | Kappa | null | null | null | null | null |
6azm | D | C | 0 | F | peptide | null | circumsporozoite protein nanp 5-mer | IMMUNE SYSTEM | 09/11/17 | Crystal structure of the 580 germline antibody bound to circumsporozoite protein NANP 5-mer | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | plasmodium falciparum | Scally, S.W., Bosch, A., Triller, G., Wardemann, H., Julien, J.P. | 1.6 | X-RAY DIFFRACTION | 0.199 | 0.166 | false | true | IGHV3 | IGKV4 | Kappa | null | null | null | null | null |
7mem | I | K | 0 | F | protein | null | hemagglutinin ha1 chain | Viral protein/IMMUNE SYSTEM | 04/06/21 | CryoEM structure of monoclonal Fab 045-09 2B05 binding the lateral patch of influenza virus H1 HA | INFLUENZA A VIRUS (STRAIN SWL A/CALIFORNIA/04/2009 H1N1); HOMO SAPIENS | homo sapiens | homo sapiens | influenza a virus (strain swla/california/04/2009 h1n1) | Han, J., Ward, A. | 3.2 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
3iyw | K | M | 0 | C | protein | null | polyprotein | VIRUS | 06/18/10 | West Nile virus in complex with Fab fragments of MAb CR4354 (fitted coordinates of envelope proteins and Fab fragments of one icosahedral ASU) | WEST NILE VIRUS; HOMO SAPIENS | homo sapiens | homo sapiens | west nile virus | Rossmann, M.G., Kaufmann, B. | 13.7 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
7f9y | N | null | 0 | A | B | G | protein | protein | protein | NA | NA | NA | engineered g-alpha-q subunit | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | guanine nucleotide-binding protein g(i)/g(s)/g(o) subunitgamma-2 | MEMBRANE PROTEIN | 07/05/21 | ghrelin-bound ghrelin receptor in complex with Gq | HOMO SAPIENS; LAMA GLAMA | lama glama | null | homo sapiens | homo sapiens | homo sapiens | Wang, Y., Zhuang, Y., Xu, P., Xu, H.E., Jiang, Y. | 2.9 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | null | null | null | null | null | null | null |
5ds8 | H | L | 0 | P | peptide | null | tetrapeptide gly-hpu-gly-ala | IMMUNE SYSTEM | 09/17/15 | Context-independent anti-hypusine antibody FabHpu98 in complex with hypusine | ORYCTOLAGUS CUNICULUS; SYNTHETIC CONSTRUCT | oryctolagus cuniculus | oryctolagus cuniculus | synthetic construct | Zhai, Q., Carter, P.J. | 1.95 | X-RAY DIFFRACTION | 0.224 | 0.183 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
6rps | N | M | 0 | B | protein | null | carbonic anhydrase 12 | LYASE | 05/14/19 | X-ray crystal structure of carbonic anhydrase XII complexed with a theranostic monoclonal antibody fragment | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Alterio, V., Esposito, D., De Simone, G. | 2.79 | X-RAY DIFFRACTION | 0.231 | 0.203 | false | true | IGHV2 | IGKV5 | Kappa | null | null | null | null | null |
4dvb | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 02/23/12 | The crystal structure of the Fab fragment of pro-uPA antibody mAb-112 | MUS MUSCULUS | mus musculus | mus musculus | null | Jiang, L., Botkjaer, K.A., Andersen, L.M., Yuan, C., Andreasen, P.A., Huang, M. | 1.93 | X-RAY DIFFRACTION | 0.259 | 0.223 | false | false | IGHV5 | IGKV4 | Kappa | null | null | null | null | null |
5e7f | A | null | 0 | G | protein | null | major structural protein 1 | VIRAL PROTEIN | 10/12/15 | Complex between lactococcal phage Tuc2009 RBP head domain and a nanobody (L06) | CAMELUS DROMEDARIUS; LACTOCOCCUS PHAGE TUC2009 | camelus dromedarius | null | lactococcus phage tuc2009 | Legrand, P., Collins, B., Blangy, S., Murphy, J., Spinelli, S., Gutierrez, C., Richet, N., Kellenberger, C., Desmyter, A., Mahony, J., van Sinderen, D., Cambillau, C. | 2.7 | X-RAY DIFFRACTION | 0.208 | 0.194 | false | true | IGHV1 | null | null | 0 | -10.96983 | SPR | null | TBD |
6zrv | B | null | 0 | A | protein | null | plasminogen activator inhibitor 1 | HYDROLASE | 07/15/20 | Crystal Structure of Stabilized Active Plasminogen Activator Inhibitor-1 (PAI-1-W175F) in Complex with an Inhibitory Nanobody (VHH-s-a93, Nb93) | HOMO SAPIENS; VICUGNA PACOS | vicugna pacos | null | homo sapiens | Sillen, M., Weeks, S.D., Strelkov, S.V., Declerck, P.J. | 1.88 | X-RAY DIFFRACTION | 0.233 | 0.197 | false | true | IGHV1 | null | null | null | null | null | null | null |
5mth | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 01/09/17 | Structure of DC8E8 Fab at pH 6.5 crystallized in spacegroup P21 | MUS MUSCULUS | mus musculus | mus musculus | null | Skrabana, R., Novak, M., Cehlar, O., Kontsekova, E. | 1.73 | X-RAY DIFFRACTION | 0.236 | 0.185 | false | false | IGHV1 | IGKV8 | Kappa | null | null | null | null | null |
4jlr | A | B | 0 | C | protein | null | rsv_1isea designed scaffold | IMMUNE SYSTEM | 03/12/13 | Crystal structure of a designed Respiratory Syncytial Virus Immunogen in complex with Motavizumab | null | null | null | null | Rupert, P.B., Correia, B., Schief, W., Strong, R.K. | 2.71 | X-RAY DIFFRACTION | 0.249 | 0.191 | false | true | IGHV2 | IGKV1 | Kappa | 0 | -14.357753 | SPR | null | TBD |
7zf6 | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 04/01/22 | Omi-12 Fab | HOMO SAPIENS | homo sapiens | homo sapiens | null | Zhou, D., Huo, J., Ren, J., Stuart, D.I. | 2.21 | X-RAY DIFFRACTION | 0.265 | 0.235 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
4laq | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 06/20/13 | Crystal structures of a therapeutic single chain antibody in the free Form and in complex with amphetamine and 4-hydroxymethamphetamine | MUS MUSCULUS | mus musculus | mus musculus | null | Celikel, R., Gokulan, K., Peterson, E.C., Varughese, K.I. | 2.8 | X-RAY DIFFRACTION | 0.270 | 0.208 | false | true | IGHV3 | IGKV4 | Kappa | null | null | null | null | null |
6xkr | H | L | 0 | P | protein | null | programmed cell death protein 1 | ANTITUMOR PROTEIN/IMMUNE SYSTEM | 06/27/20 | Structure of Sasanlimab Fab in complex with PD-1 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Kimberlin, C.R., Chin, S.M. | 2.59 | X-RAY DIFFRACTION | 0.271 | 0.219 | false | true | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
3or6 | A | B | 0 | C | protein | null | voltage-gated potassium channel | IMMUNE SYSTEM/TRANSPORT PROTEIN | 09/06/10 | On the structural basis of modal gating behavior in K+channels - E71Q | MUS MUSCULUS; STREPTOMYCES LIVIDANS | mus musculus | mus musculus | streptomyces lividans | Chakrapani, S., Cordero-Morales, J.F., Jogini, V., Perozo, E. | 2.7 | X-RAY DIFFRACTION | 0.268 | 0.226 | false | false | IGHV1 | IGKV5 | Kappa | null | null | null | null | null |
2x7l | J | K | 0 | Q | protein | null | hiv rev | IMMUNE SYSTEM | 03/01/10 | Implications of the HIV-1 Rev dimer structure at 3.2A resolution for multimeric binding to the Rev response element | UNCLASSIFIED; HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 BH10 | unclassified | unclassified | human immunodeficiency virus type 3 | DiMattia, M.A., Watts, N.R., Stahl, S.J., Rader, C., Wingfield, P.T., Stuart, D.I., Steven, A.C., Grimes, J.M. | 3.17 | X-RAY DIFFRACTION | 0.2500 | 0.2337 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
1dqd | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 01/04/00 | CRYSTAL STRUCTURE OF FAB HGR-2 F6, A COMPETITIVE ANTAGONIST OF THE GLUCAGON RECEPTOR | MUS MUSCULUS | mus musculus | mus musculus | null | Wright, L.M., Brzozowski, A.M., Hubbard, R.E., Pike, A.C.W., Roberts, S.M., Skovgaard, R.N., Svendsen, I., Vissing, H., Bywater, R.P. | 2.1 | X-RAY DIFFRACTION | 0.315 | 0.217 | false | false | IGHV3 | IGKV4 | Kappa | null | null | null | null | null |
7ooi | B | null | 0 | null | null | null | null | IMMUNE SYSTEM | 05/27/21 | Anti-EphA1 JD1 VH domain | HOMO SAPIENS | homo sapiens | null | null | Ereno-Orbea, J., Nilvebrant, J., Sidhu, S., Julien, J.P. | 2.28 | X-RAY DIFFRACTION | 0.297 | 0.269 | false | true | IGHV3 | null | null | null | null | null | null | null |
3q6f | D | C | 0 | null | null | null | null | IMMUNE SYSTEM | 12/31/10 | Crystal structure of Fab of human mAb 2909 specific for quaternary neutralizing epitope of HIV-1 gp120 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Spurrier, B., Sampson, J., Totrov, M., Li, H., O'Neal, T., William, C., Robinson, J., Gorny, M.K., Zolla-Pazner, S., Kong, X.P. | 3.192 | X-RAY DIFFRACTION | 0.243 | 0.199 | false | false | IGHV3 | IGLV3 | Lambda | null | null | null | null | null |
5c8j | E | F | 0 | J | protein | null | protein mj0480 | MEMBRANE PROTEIN | 06/25/15 | A YidC-like protein in the archaeal plasma membrane | HOMO SAPIENS; METHANOCALDOCOCCUS JANNASCHII (STRAIN ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) | homo sapiens | homo sapiens | methanocaldococcus jannaschii (strain atcc43067 / dsm 2661 / jal-1 / jcm 10045 / nbrc 100440) | Borowska, M.T., Dominik, P.K., Anghel, S.A., Kossiakoff, A.A., Keenan, R.J. | 3.502 | X-RAY DIFFRACTION | 0.302 | 0.253 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
7pg8 | R | P | 0 | T | protein | null | ion transport protein,voltage-gated sodium channel | MEMBRANE PROTEIN | 08/13/21 | NaV_Ae1/Sp1CTD_pore-ANT05 complex | HOMO SAPIENS; ALKALILIMNICOLA EHRLICHII MLHE-1; RUEGERIA POMEROYI DSS-3 | homo sapiens | homo sapiens | alkalilimnicola ehrlichii mlhe-1, ruegeriapomeroyi dss-3 | Lolicato, M., Arrigoni, C. | 4.5 | X-RAY DIFFRACTION | 0.352 | 0.303 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6x97 | E | F | 0 | C | protein | null | bg505 hiv-1 env gp120 | VIRAL PROTEIN/IMMUNE SYSTEM | 06/02/20 | Cryo-EM model of HIV-1 Env BG505 SOSIP.664 in complex with rabbit monoclonal antibody 11A fragment antigen binding variable domain | HUMAN IMMUNODEFICIENCY VIRUS 1; ORYCTOLAGUS CUNICULUS | oryctolagus cuniculus | oryctolagus cuniculus | human immunodeficiency virus 1 | Ozorowski, G., Cottrell, C.A., Ward, A.B. | 3.65 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
3r06 | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 03/07/11 | Crystal structure of anti-mouse CD3epsilon antibody 2C11 Fab fragment | CRICETULUS MIGRATORIUS | cricetulus migratorius | cricetulus migratorius | null | Shore, D.A., Zhu, X., Wilson, I.A. | 2.5 | X-RAY DIFFRACTION | 0.236 | 0.191 | false | true | IGHV5 | IGKV14 | Kappa | null | null | null | null | null |
7uds | F | G | 0 | A | a | protein | protein | NA | NA | glycoprotein g2 | unknown | VIRAL PROTEIN/IMMUNE SYSTEM | 03/20/22 | Structure of lineage I (Pinneo) Lassa virus glycoprotein bound to Fab 25.10C | HOMO SAPIENS; LASSA MAMMARENAVIRUS | homo sapiens | homo sapiens | lassa mammarenavirus | lassa mammarenavirus | Buck, T.K., Enriquez, A.E., Hastie, K.M. | 3.1 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
2kh2 | B | b | 26 | A | protein | null | interleukin-1 beta | Cytokine/IMMUNE SYSTEM | 03/23/09 | Solution structure of a scFv-IL-1B complex | HOMO SAPIENS; MUS MUSCULUS | mus musculus | null | homo sapiens | Wilkinson, I.C., Hall, C.J., Veverka, V., Muskett, F.W., Stephens, P.E., Taylor, R.J., Henry, A.J., Carr, M.D. | NOT | SOLUTION NMR | null | null | true | true | unknown | unknown | unknown | null | null | null | null | null |
6vu2 | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 02/14/20 | M1214_N1 Fab structure | HUMAN IMMUNODEFICIENCY VIRUS | human immunodeficiency virus | human immunodeficiency virus | null | Pan, R., Kong, X. | 2.19 | X-RAY DIFFRACTION | 0.216 | 0.177 | false | true | unknown | unknown | unknown | null | null | null | null | null |
7k75 | C | D | 0 | F | peptide | null | pfcsp n-terminal peptide p17 | IMMUNE SYSTEM | 09/22/20 | Crystal structure of MAD2-6 IgA Fab in complex with PfCSP N-terminal peptide. | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | plasmodium falciparum | Pholcharee, T., Wilson, I.A. | 2.5 | X-RAY DIFFRACTION | 0.236 | 0.192 | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
3gkz | a | A | 0 | A | Hapten | B40 | (2S)-N-METHYL-1-PHENYLPROPAN-2-AMINE | IMMUNE SYSTEM | 03/11/09 | Crystal structures of a therapeutic single chain antibody in complex methamphetamine | MUS MUSCULUS | null | mus musculus | mus musculus | Celikel, R., Peterson, E.C., Owens, M., Varughese, K.I. | 1.9 | X-RAY DIFFRACTION | 0.235 | 0.210 | true | true | unknown | unknown | unknown | 0 | -10.913953 | Unknown | null | TBD |
5wob | O | P | 0 | D | protein | null | insulin | HYDROLASE | 08/01/17 | Crystal Structure Analysis of Fab1-Bound Human Insulin Degrading Enzyme (IDE) in Complex with Insulin | HOMO SAPIENS; MUS MUSCULOIDES | mus musculoides | mus musculoides | homo sapiens | McCord, L.A., Liang, W.G., Farcasanu, M., Wang, A.G., Koide, S., Tang, W.J. | 3.95 | X-RAY DIFFRACTION | 0.291 | 0.243 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
3eff | D | C | 0 | K | L | protein | protein | NA | NA | voltage-gated potassium channel | voltage-gated potassium channel | MEMBRANE PROTEIN | 09/08/08 | The Crystal Structure of Full-Length KcsA in its Closed Conformation | MUS MUSCULUS; STREPTOMYCES LIVIDANS | mus musculus | mus musculus | streptomyces lividans | streptomyces lividans | Uysal, S., Vasquez, V., Tereshko, T., Esaki, K., Fellouse,F.A., Sidhu, S.S., Koide, S., Perozo, E., Kossiakoff, A. | 3.8 | X-RAY DIFFRACTION | 0.331 | 0.270 | false | false | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
1v7n | J | N | 0 | Y | protein | null | thrombopoietin | IMMUNE SYSTEM/CYTOKINE | 12/18/03 | Human Thrombopoietin Functional Domain Complexed To Neutralizing Antibody TN1 Fab | MUS MUSCULUS; HOMO SAPIENS | mus musculus | mus musculus | homo sapiens | Feese, M.D., Tamada, T., Kato, Y., Maeda, Y., Hirose, M., Matsukura, Y., Shigematsu, H., Kato, T., Miyazaki, H., Kuroki, R. | 3.3 | X-RAY DIFFRACTION | 0.305 | 0.167 | false | true | IGHV6 | IGKV4 | Kappa | null | null | null | null | null |
4rqs | D | C | 0 | G | protein | null | hiv-1 yu2 gp120 core chimeric protein | IMMUNE SYSTEM | 11/05/14 | Crystal structure of fully glycosylated HIV-1 gp120 core bound to CD4 and 17b Fab | CRICETULUS GRISEUS; HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Kong, L., Wilson, I.A., Kwong, P.D. | 4.493 | X-RAY DIFFRACTION | 0.322 | 0.276 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
6vvu | E | F | 0 | C | protein | null | tryptase alpha/beta-1 | HYDROLASE/IMMUNE SYSTEM | 02/18/20 | Anti-Tryptase fab E104.v1 bound to tryptase | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Ultsch, M., Koerber, J.T. | 3.0 | X-RAY DIFFRACTION | 0.232 | 0.187 | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
5m7q | A | null | 0 | null | null | null | null | IMMUNE SYSTEM | 10/28/16 | Engineering the Thermostability of Nanobodies - NbD2 | CAMELUS DROMEDARIUS | camelus dromedarius | null | null | Soler, N., Kunz, P., Muyldermans, S. | 1.8 | X-RAY DIFFRACTION | 0.249 | 0.196 | false | true | IGHV1 | null | null | null | null | null | null | null |
1xcq | H | G | 0 | S | peptide | null | capsid protein c | IMMUNE SYSTEM | 09/03/04 | Complex HCV core-Fab 19D9D6-Protein L mutant (D55A,L57H,Y64W) in space group P21 | FINEGOLDIA MAGNA; MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | null | Menez, R., Housden, N.G., Harrison, S., Jolivet-Reynaud, C., Gore, M.G., Stura, E.A. | 3.5 | X-RAY DIFFRACTION | 0.264 | 0.192 | false | false | IGHV9 | IGKV8 | Kappa | null | null | null | null | null |
6pb1 | N | null | 0 | A | B | protein | protein | NA | NA | guanine nucleotide-binding protein g(s) subunit alphaisoforms short,guanine nucleotide-binding protein g(i) subunit alpha- 1,guanine nucleotide-binding protein g(s) subunit alpha isoforms short | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | SIGNALING PROTEIN | 06/12/19 | Cryo-EM structure of Urocortin 1-bound Corticotropin-releasing factor 2 receptor in complex with Gs protein and Nb35 | HOMO SAPIENS; SYNTHETIC CONSTRUCT; SYNTHETIC CONSTRUCT | synthetic construct | null | homo sapiens | homo sapiens | Ma, S., Shen, Q., Zhao, L.-H., Mao, C., Zhou, X.E., Shen, D.-D., de Waal, P.W., Bi, P., Li, C., Jiang, Y., Wang, M.-W., Sexton, P.M., Wootten, D., Melcher, K., Zhang, Y., Xu, H.E. | 2.8 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | null | null | null | null | null | null | null |
7m6i | M | N | 0 | A | protein | null | spike glycoprotein | VIRAL PROTEIN/ANTIVIRAL PROTEIN | 03/25/21 | Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, BG1-24 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Barnes, C.O., Bjorkman, P.J. | 4 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
7lqw | H | L | 0 | C | protein | null | spike glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 02/15/21 | Cryo-EM structure of NTD-directed neutralizing antibody 2-17 Fab in complex with SARS-CoV-2 S2P spike | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Gorman, J., Rapp, M., Kwong, P.D., Shapiro, L. | 4.47 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
7sjs | H | L | 0 | C | peptide | null | stem helix peptide of spike protein s2' | IMMUNE SYSTEM | 10/18/21 | Crystal structure of SARS-CoV-2 spike stem helix peptide in complex with neutralizing antibody CC40.8 | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Yuan, M., Wilson, I.A. | 1.612 | X-RAY DIFFRACTION | 0.206 | 0.174 | false | true | IGHV3 | IGLV3 | Lambda | null | null | null | null | null |
6qkd | H | null | 0 | null | null | null | null | IMMUNE SYSTEM | 01/29/19 | CRYSTAL STRUCTURE OF vhh-based FAB-fragment of antibody BCD-085 | LAMA GLAMA | lama glama | null | null | Kostareva, O.S., Kolyadenko, I.A., Ulitin, A.B., Ekimova, V.M., Evdokimov, S.R., Garber, M.B., Tishchenko, T.V., Gabdulkhakov, A.G. | 1.9 | X-RAY DIFFRACTION | 0.228 | 0.169 | false | true | IGHV1 | null | null | null | null | null | null | null |
6nf5 | H | L | 0 | A | protein | null | hiv-1 env bg505 md64 n332-gt5 sosip gp120 | VIRAL PROTEIN/immune system | 12/18/18 | BG505 MD64 N332-GT5 SOSIP trimer in complex with BG18-like precursor HMP1 fragmentantigen binding and base-binding RM20A3 fragment antigen binding | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS; MACACA MULATTA | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Ozorowski, G., Torres, J.L., Steichen, J.M., Schief, W.R., Ward, A.B. | 3.71 | ELECTRON MICROSCOPY | null | null | false | true | IGHV4 | IGLV3 | Lambda | null | null | null | null | null |
4mhj | R | Q | 0 | O | protein | null | hemagglutinin ha1 chain | VIRAL PROTEIN/IMMUNE SYSTEM | 08/29/13 | Crystal structure of Fab H5M9 in complex with influenza virus hemagglutinin from A/goose/Guangdong/1/96 (H5N1) | INFLUENZA A VIRUS; MUS MUSCULUS | mus musculus | mus musculus | influenza a virus | Zhu, X., Wilson, I.A. | 6.98 | X-RAY DIFFRACTION | 0.387 | 0.377 | false | true | IGHV1 | IGKV3 | Kappa | 0 | -12.278197 | BLI | null | TBD |
7nvl | n | null | 0 | e | protein | null | unknown | CHAPERONE | 03/15/21 | Human TRiC complex in closed state with nanobody bound (Consensus Map) | LAMA GLAMA; HOMO SAPIENS | lama glama | null | homo sapiens | Kelly, J.J., Chi, G., Bulawa, C., Paavilainen, V.O., Bountra, C., Huiskonen, J.T., Yue, W., Structural Genomics Consortium (SGC) | 2.5 | ELECTRON MICROSCOPY | null | null | false | false | IGHV1 | null | null | null | null | null | null | null |
4tnv | J | M | 0 | E | protein | null | avermectin-sensitive glutamate-gated chloride channel gluclalpha | Transport Protein/immune System | 06/05/14 | C. elegans glutamate-gated chloride channel (GluCl) in complex with Fab in a non-conducting conformation | CAENORHABDITIS ELEGANS; MUS MUSCULUS | mus musculus | mus musculus | caenorhabditis elegans | Althoff, T., Hibbs, R.E., Banerjee, S., Gouaux, E. | 3.6 | X-RAY DIFFRACTION | 0.283 | 0.261 | false | false | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
7bue | G | I | 0 | B | protein | null | dengue serotype 2 e protein ectodomain | VIRUS | 05/13/20 | Cryo-EM structure of Dengue virus serotype 2 complexed with Fab SIgN-3C at pH 5.0 | HOMO SAPIENS; DENGUE VIRUS 2 | homo sapiens | homo sapiens | dengue virus 2 | Zhang, S., Chew, S.V., Lim, X.N., Ng, T.S., Kostyuchenko, V.A., Lok, S.M. | 7.8 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
7lu9 | i | j | 0 | B | carbohydrate | MAN | ALPHA-D-MANNOSE | VIRAL PROTEIN/IMMUNE SYSTEM | 02/21/21 | Cryo-EM structure of DH851.3 bound to HIV-1 CH505 Env | MACACA MULATTA; HUMAN IMMUNODEFICIENCY VIRUS 1 | macaca mulatta | macaca mulatta | null | Manne, K., Edwards, R.J., Acharya, P. | 5.6 | ELECTRON MICROSCOPY | null | null | false | false | IGHV2 | IGLV2 | Lambda | null | null | null | null | null |
7s6c | E | G | 0 | A | protein | null | 6-deoxyerythronolide-b synthase erya2, modules 3 and 4,lsd14 polyketide synthase fusion | BIOSYNTHETIC PROTEIN | 09/13/21 | CryoEM structure of modular PKS holo-Lsd14 stalled at the condensation step and bound to antibody fragment 1B2, composite structure | SACCHAROPOLYSPORA ERYTHRAEA; STREPTOMYCES LASALOCIDI; HOMO SAPIENS | homo sapiens | homo sapiens | saccharopolyspora erythraea, streptomyceslasalocidi | Bagde, S.R., Kim, C.-Y., Fromme, J.C. | 3.1 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV2 | Kappa | null | null | null | null | null |
3qnx | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 02/09/11 | Orthorhombic form of human IgA1 Fab fragment, sharing same Fv as IgG | HOMO SAPIENS | homo sapiens | homo sapiens | null | Trajtenberg, F., Correa, A., Buschiazzo, A. | 2.2 | X-RAY DIFFRACTION | 0.224 | 0.181 | false | false | IGHV3 | IGKV2 | Kappa | null | null | null | null | null |
7cyp | E | D | 0 | A | protein | null | sars-cov-2 spike glycoprotein | VIRAL PROTEIN | 09/04/20 | Complex of SARS-CoV-2 spike trimer with its neutralizing antibody HB27 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Wang, X., Zhu, L. | 3.5 | ELECTRON MICROSCOPY | null | null | false | true | IGHV5 | IGKV3 | Kappa | null | null | null | null | null |
7kmd | A | E | 0 | T | protein | null | envelope glycoprotein gp41 | VIRAL PROTEIN/IMMUNE SYSTEM | 11/02/20 | Crystal structure of a HIV-1 clade C isolate Du172.17 HR1.R4.664 Env trimer in complex with human Fabs PGT124 and 35O22 | HOMO SAPIENS; HUMAN IMMUNODEFICIENCY VIRUS 1 | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Kumar, S., Wilson, I.A. | 3.39229 | X-RAY DIFFRACTION | 0.292 | 0.242 | false | true | unknown | unknown | unknown | null | null | null | null | null |
6cue | Q | R | 0 | C | protein | null | envelope glycoprotein gp120 | VIRAL PROTEIN | 03/26/18 | Cryo-EM structure at 4.0 A resolution of vaccine-elicited antibody vFP7.04 in complex with HIV-1 Env BG505 DS-SOSIP, and antibodies VRC03 and PGT122 | HUMAN IMMUNODEFICIENCY VIRUS 1; MUS MUSCULUS; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Acharya, P., Carragher, B., Potter, C.S., Kwong, P.D. | 4.0 | ELECTRON MICROSCOPY | null | null | false | true | unknown | unknown | unknown | null | null | null | null | null |
3ixy | G | H | 0 | A | protein | null | envelope protein e | VIRUS | 02/26/09 | The pseudo-atomic structure of dengue immature virus in complex with Fab fragments of the anti-fusion loop antibody E53 | DENGUE VIRUS 2; MUS MUSCULUS | mus musculus | mus musculus | dengue virus 2 | Cherrier, M.V., Kaufmann, B., Nybakken, G.E., Lok, S.M., Warren, J.T., Nelson, C.A., Kostyuchenko, V.A., Holdaway, H.A., Chipman, P.R., Kuhn, R.J., Diamond, M.S., Rossmann, M.G., Fremont, D.H. | 23 | ELECTRON MICROSCOPY | null | null | false | true | IGHV7 | IGKV4 | Kappa | null | null | null | null | null |
5ijv | F | E | 0 | null | null | null | null | IMMUNE SYSTEM | 03/02/16 | Crystal structure of bovine Fab E03 | BOS TAURUS | bos taurus | bos taurus | null | Stanfield, R.L., Wilson, I.A. | 2.2 | X-RAY DIFFRACTION | 0.247 | 0.204 | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
7pnq | H | L | 0 | A | protein | null | spike glycoprotein | VIRAL PROTEIN | 09/07/21 | Human coronavirus OC43 spike glycoprotein ectodomain in complex with the 43E6 antibody Fab fragment | HOMO SAPIENS; HUMAN CORONAVIRUS OC43 | homo sapiens | homo sapiens | human coronavirus oc43 | Hurdiss, D.L. | 3.7 | ELECTRON MICROSCOPY | null | null | false | true | IGHV4 | IGKV3 | Kappa | null | null | null | null | null |
4xwo | K | L | 0 | H | protein | null | atpase get3 | HYDROLASE/TRANSPORT PROTEIN | 01/29/15 | Structure of Get3 bound to the transmembrane domain of Sec22 | HOMO SAPIENS, SYNTHETIC CONSTRUCT; SACCHAROMYCES CEREVISIAE (ATCC 204508 / S288C); SACCHAROMYCES CEREVISIAE | homo sapiens, synthetic construct | homo sapiens, synthetic construct | saccharomyces cerevisiae (atcc 204508 / s288c) | Mateja, A., Paduch, M., Chang, H.-Y., Szydlowska, A., Kossiakoff, A.A., Hegde, R.S., Keenan, R.J. | 2.75 | X-RAY DIFFRACTION | 0.247 | 0.196 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
4hlz | G | H | 0 | B | A | protein | protein | NA | NA | hemagglutinin ha2 | hemagglutinin ha1 | VIRAL PROTEIN/IMMUNE SYSTEM | 10/17/12 | Crystal Structure of Fab C179 in Complex with a H2N2 influenza virus hemagglutinin | INFLUENZA A VIRUS; MUS MUSCULUS | mus musculus | mus musculus | influenza a virus | influenza a virus | Dreyfus, C., Wilson, I.A. | 2.9 | X-RAY DIFFRACTION | 0.284 | 0.228 | false | true | IGHV7 | IGKV12 | Kappa | 0 | -11.867518 | BLI | null | TBD |
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