pdb stringlengths 4 4 | Hchain stringclasses 59
values | Lchain stringclasses 60
values | model int64 0 76 | antigen_chain stringclasses 386
values | antigen_type stringclasses 24
values | antigen_het_name stringclasses 240
values | antigen_name stringlengths 1 396 ⌀ | short_header stringclasses 448
values | date stringlengths 8 8 | compound stringlengths 4 243 | organism stringlengths 3 175 ⌀ | heavy_species stringclasses 121
values | light_species stringclasses 67
values | antigen_species stringclasses 937
values | authors stringlengths 6 762 | resolution stringlengths 1 8 | method stringclasses 10
values | r_free stringclasses 354
values | r_factor stringclasses 342
values | scfv bool 2
classes | engineered bool 2
classes | heavy_subclass stringclasses 14
values | light_subclass stringclasses 35
values | light_ctype stringclasses 3
values | affinity float64 0 0 ⌀ | delta_g float64 -16.91 -5.04 ⌀ | affinity_method stringclasses 11
values | temperature float64 4 37 ⌀ | pmid stringclasses 157
values |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
3chn | C | O | 4 | null | null | null | null | IMMUNE SYSTEM | 03/10/08 | Solution structure of human secretory IgA1 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Bonner, A., Almogren, A., Furtado, P.B., Kerr, M.A., Perkins, S.J. | NOT | SOLUTION SCATTERING / HOMOLOGY MODEL | null | null | false | false | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
7t4r | G | H | 0 | B | protein | null | envelope glycoprotein h | VIRAL PROTEIN/Immune System | 12/10/21 | CryoEM structure of the HCMV Pentamer gH/gL/UL128/UL130/UL131A in complex with THBD and neutralizing fabs MSL-109 and 13H11 | HOMO SAPIENS; HUMAN BETAHERPESVIRUS 5 | homo sapiens | homo sapiens | human betaherpesvirus 5 | Kschonsak, M., Johnson, M.C., Schelling, R., Green, E.M., Rouge, L., Ho, H., Patel, N., Kilic, C., Kraft, E., Arthur, C.P., Rohou, A.L., Comps-Agrar, L., Martinez-Martin, N., Perez, L., Payandeh, J., Ciferri, C. | 3.3 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
1ken | H | L | 0 | A | protein | null | hemagglutinin ha1 | Viral protein/Immune system | 11/16/01 | INFLUENZA VIRUS HEMAGGLUTININ COMPLEXED WITH AN ANTIBODY THAT PREVENTS THE HEMAGGLUTININ LOW PH FUSOGENIC TRANSITION | INFLUENZA A VIRUS (A/X-31(H3N2)); MUS MUSCULUS | mus musculus | mus musculus | influenza a virus (a/x-31(h3n2)) | Barbey-Martin, C., Gigant, B., Bizebard, T., Calder, L.J., Wharto, S.A., Skehel, J.J., Knossow, M. | 3.5 | X-RAY DIFFRACTION | 0.323 | 0.255 | false | false | IGHV3 | IGKV4 | Kappa | null | null | null | null | null |
6h7l | C | null | 0 | A | protein | null | beta-1 adrenergic receptor | IMMUNE SYSTEM | 07/31/18 | ACTIVATED TURKEY BETA1 ADRENOCEPTOR WITH BOUND PARTIAL AGONIST DOBUTAMINE AND NANOBODY Nb6B9 | ESCHERICHIA COLI (STRAIN K12); MELEAGRIS GALLOPAVO; LAMA GLAMA | lama glama | null | meleagris gallopavo | Warne, T., Edwards, P.C., Dore, A.S., Leslie, A.G.W., Tate, c.g. | 2.7 | X-RAY DIFFRACTION | 0.278 | 0.241 | false | true | IGHV1 | null | null | null | null | null | null | null |
2nlj | B | A | 0 | C | protein | null | voltage-gated potassium channel | MEMBRANE PROTEIN | 10/20/06 | Potassium Channel KcsA(M96V)-Fab complex in KCl | STREPTOMYCES LIVIDANS; MUS MUSCULUS | mus musculus | mus musculus | streptomyces lividans | Lockless, S.W., Zhou, M., MacKinnon, R. | 2.52 | X-RAY DIFFRACTION | 0.255 | 0.235 | false | false | IGHV1 | IGKV5 | Kappa | null | null | null | null | null |
3cm9 | C | N | 9 | null | null | null | null | IMMUNE SYSTEM | 03/21/08 | Solution Structure of Human SIgA2 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Bonner, A., Almogren, A., Furtado, P.B., Kerr, M.A., Perkins, S.J. | NOT | SOLUTION SCATTERING | null | null | false | false | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
6wps | H | L | 0 | A | protein | null | sars-cov-2 spike glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 05/27/20 | Structure of the SARS-CoV-2 spike glycoprotein in complex with the S309 neutralizing antibody Fab fragment | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Pinto, D., Park, Y.J., Beltramello, M., Walls, A.C., Tortorici, M.A., Bianchi, S., Jaconi, S., Culap, K., Zatta, F., De Marco, A., Peter, A., Guarino, B., Spreafico, R., Cameroni, E., Case, J.B., Chen, R.E., Havenar-Daughton, C., Snell, G., Virgin, H.W., Lanzavecchia, A., Diamond, M.S., Fink, K., Veesler, D., Corti, D.... | 3.1 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
6n4y | H | null | 0 | C | protein | null | metabotropic glutamate receptor 5 | MEMBRANE PROTEIN | 11/20/18 | Metabotropic Glutamate Receptor 5 Extracellular Domain with Nb43 | HOMO SAPIENS; LAMA GLAMA | lama glama | null | homo sapiens | Koehl, A., Hu, H., Feng, D., Sun, B., Chu, M., Weis, W.I., Mathiesen, J.M., Skiniotis, G., Kobilka, B.K. | 3.262 | X-RAY DIFFRACTION | 0.251 | 0.199 | false | true | IGHV1 | null | null | null | null | null | null | null |
6ymq | E | e | 0 | 0 | protein | null | unknown | IMMUNE SYSTEM | 04/09/20 | TREM2 extracellular domain (19-131) in complex with single-chain variable 4 (scFv-4) | HOMO SAPIENS | homo sapiens | null | null | Szykowska, A., Preger, C., Scacioc, A., Mukhopadhyay, S.M.M., McKinley, G., Graslund, S., Wigren, E., Persson, H., von Delft, F., Arrowsmith, C.H., Edwards, A., Bountra, C., Di Daniel, E., Davis, J.B., Burgess-Brown, N., Bullock, A. | 3.07 | X-RAY DIFFRACTION | 0.288 | 0.274 | true | true | unknown | unknown | unknown | null | null | null | null | null |
5e1h | B | null | 0 | A | protein | null | ricin | TOXIN/IMMUNE SYSTEM | 09/29/15 | Ricin toxin in complex with neutralizing single chain monoclonal antibodies (VHHs) | CAMELIDAE; RICINUS COMMUNIS | camelidae | null | ricinus communis | Rudolph, M.J., Vance, D., Shoemaker, C., Mantis, N. | 2.032 | X-RAY DIFFRACTION | 0.257 | 0.204 | false | true | IGHV1 | null | null | null | null | null | null | null |
3fct | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 06/13/99 | MATURE METAL CHELATASE CATALYTIC ANTIBODY WITH HAPTEN | HOMO SAPIENS | homo sapiens | homo sapiens | null | Romesberg, F.E., Santarsiero, B.D., Barnes, D., Yin, J., Spiller, B., Schultz, P.G., Stevens, R.C. | 2.4 | X-RAY DIFFRACTION | 0.293 | 0.206 | false | true | IGHV1 | IGKV6 | Kappa | null | null | null | null | null |
3mcl | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 03/29/10 | Anti-beta-amyloid antibody c706 fab in space group P21 | MUS MUSCULUS, HOMO SAPIENS | mus musculus, homo sapiens | mus musculus, homo sapiens | null | Teplyakov, A., Obmolova, G., Gilliland, G.L. | 1.7 | X-RAY DIFFRACTION | 0.260 | 0.203 | false | true | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
5lmw | A | null | 0 | null | null | null | null | IMMUNE SYSTEM | 08/01/16 | Llama nanobody PorM_02 | LAMA GLAMA | lama glama | null | null | Roche, J., Gaubert, A., Leone, P., Roussel, A. | 1.5 | X-RAY DIFFRACTION | 0.196 | 0.188 | false | true | IGHV1 | null | null | null | null | null | null | null |
7t4q | I | H | 0 | D | B | protein | protein | NA | NA | envelope glycoprotein ul130 | envelope glycoprotein l | VIRAL PROTEIN/Immune System | 12/10/21 | CryoEM structure of the HCMV Pentamer gH/gL/UL128/UL130/UL131A in complex with neutralizing fabs 2C12, 7I13 and 13H11 | HUMAN BETAHERPESVIRUS 5; HOMO SAPIENS | homo sapiens | homo sapiens | human betaherpesvirus 5 | human betaherpesvirus 5 | Kschonsak, M., Johnson, M.C., Schelling, R., Green, E.M., Rouge, L., Ho, H., Patel, N., Kilic, C., Kraft, E., Arthur, C.P., Rohou, A.L., Comps-Agrar, L., Martinez-Martin, N., Perez, L., Payandeh, J., Ciferri, C. | 2.9 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
6apd | D | E | 0 | A | protein | null | fusion glycoprotein f0,envelope glycoprotein | IMMUNE SYSTEM | 08/17/17 | Crystal structure of RSV F bound by AM22 and the infant antibody ADI-19425 | RESPIRATORY SYNCYTIAL VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | respiratory syncytial virus, humanimmunodeficiency virus 1 | Wrapp, D., McLellan, J.S. | 4.1 | X-RAY DIFFRACTION | 0.256 | 0.204 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
7b18 | E | null | 0 | A | protein | null | spike glycoprotein | VIRAL PROTEIN | 11/24/20 | SARS-CoV-spike bound to two neutralising nanobodies | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; LAMA GLAMA; VICUGNA PACOS | vicugna pacos | null | severe acute respiratory syndrome coronavirus2 | Hallberg, B.M., Das, H. | 2.62 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
7sfx | A | B | 0 | E | peptide | null | cd99 antigen peptide | IMMUNE SYSTEM | 10/04/21 | 10A1 Fab in complex with CD99 peptide | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | homo sapiens | Romero, L.A., Hattori, T., Koide, S. | 3.1 | X-RAY DIFFRACTION | 0.248 | 0.226 | false | true | IGHV6 | IGLV3 | Lambda | null | null | null | null | null |
4tnw | X | i | 0 | S | protein | null | avermectin-sensitive glutamate-gated chloride channel gluclalpha | TRANSPORT PROTEIN/IMMUNE SYSTEM | 06/05/14 | C. elegans glutamate-gated chloride channel (GluCl) in complex with Fab and POPC in a lipid-modulated conformation | CAENORHABDITIS ELEGANS; MUS MUSCULUS | mus musculus | mus musculus | caenorhabditis elegans | Althoff, T., Hibbs, R.E., Banerjee, S., Gouaux, E. | 3.2 | X-RAY DIFFRACTION | 0.251 | 0.227 | false | false | unknown | unknown | unknown | null | null | null | null | null |
6fbj | H | L | 0 | null | null | null | null | METAL BINDING PROTEIN | 12/19/17 | monoclonal antibody targeting Matrix metalloproteinase 7 | ESCHERICHIA COLI K-12 | escherichia coli k-12 | escherichia coli k-12 | null | Dym, O. | 2.3 | X-RAY DIFFRACTION | 0.249 | 0.207 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
3drt | B | A | 0 | C | peptide | null | scrhyb3k construct | IMMUNE SYSTEM | 07/11/08 | Crystal structure of the HIV-1 broadly neutralizing antibody 2F5 in complex with the gp41 scrambledFP-MPER scrHyb3K construct GIGAFGLLGFLAAGSKK-Ahx-K656NEQELLELDKWASLWN671 | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | null | Julien, J.-P., Bryson, S., de la Torre, B.G., Andreu, D., Nieva, J.L., Pai, E.F. | 3.3 | X-RAY DIFFRACTION | 0.229 | 0.203 | false | true | IGHV2 | IGKV1 | Kappa | null | null | null | null | null |
7jks | H | L | 0 | G | protein | null | hiv-1 gp120 core | IMMUNE SYSTEM | 07/28/20 | Crystal structure of vaccine-elicited broadly neutralizing VRC01-class antibody 2411a in complex with HIV-1 gp120 core | HUMAN IMMUNODEFICIENCY VIRUS 1; MUS MUSCULUS | mus musculus | mus musculus | human immunodeficiency virus 1 | Zhou, T., Chen, X., Kwong, P.D., Mascola, J.R. | 3.45 | X-RAY DIFFRACTION | 0.332 | 0.283 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
1vhp | A | null | 16 | null | null | null | null | IMMUNOGLOBULIN | 04/16/96 | VH-P8, NMR | HOMO SAPIENS | homo sapiens | null | null | Riechmann, L. | NOT | SOLUTION NMR | null | null | false | true | unknown | unknown | unknown | null | null | null | null | null |
4nry | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 11/27/13 | Crystal Structure of HIV-1 Neutralizing Antibody m66 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Ofek, G., Yang, Y., Kwong, P.D. | 3.14 | X-RAY DIFFRACTION | 0.256 | 0.228 | false | true | IGHV5 | IGKV1 | Kappa | null | null | null | null | null |
6foe | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 02/07/18 | BaxB01 Fab fragment | HOMO SAPIENS | homo sapiens | homo sapiens | null | Hollerweger, J., Schinagl, A., Kerschbaumer, R.J., Scheiflinger, F., Thiele, M., Goettig, P., Brandstetter, H. | 2.6 | X-RAY DIFFRACTION | 0.263 | 0.214 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
7lxz | G | I | 0 | B | protein | null | spike glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 03/05/21 | SARS-CoV-2 S/S2M11/S2L28 Global Refinement | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | McCallum, M., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 2.6 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGLV2 | Lambda | null | null | null | null | null |
6v4o | C | G | 0 | M | protein | null | neuraminidase | VIRAL PROTEIN | 11/28/19 | Structure of human 2E01 Fab in complex with influenza virus neuraminidase from B/Phuket/3073/2013 | INFLUENZA B VIRUS; HOMO SAPIENS | homo sapiens | homo sapiens | influenza b virus | Dai, Y.N., Fremont, D.H., Center for Structural Genomics of Infectious Diseases (CSGID) | 2.8 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
7kba | A | B | 0 | null | null | null | null | ANTIVIRAL PROTEIN, IMMUNE SYSTEM | 10/01/20 | Crystal structure of the HCMV pentamer-specific Fab 2-18 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Wrapp, D., McLellan, J.S. | 2.8 | X-RAY DIFFRACTION | 0.257 | 0.222 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
5ibu | G | B | 0 | null | null | null | null | IMMUNE SYSTEM | 02/22/16 | 6652 Fab (unbound) | HOMO SAPIENS | homo sapiens | homo sapiens | null | Raymond, D.D., Harrison, S.C. | 1.71 | X-RAY DIFFRACTION | 0.245 | 0.210 | false | true | IGHV5 | IGKV3 | Kappa | null | null | null | null | null |
6niu | F | G | 0 | B | protein | null | envelope protein e | Viral protein/IMMUNE SYSTEM | 12/31/18 | Crystal structure of a human anti-ZIKV-DENV neutralizing antibody MZ4 in complex with ZIKV E glycoprotein | HOMO SAPIENS; ZIKA VIRUS (ISOLATE ZIKV/HUMAN/FRENCH POLYNESIA/10087PF/2013) | homo sapiens | homo sapiens | zika virus (isolate zikv/human/frenchpolynesia/10087pf/2013) | Sankhala, R.S., Dussupt, V., Donofrio, G., Choe, M., Modjarrad, K., Michael, N.L., Krebs, S.J., Joyce, M.G. | 4.303 | X-RAY DIFFRACTION | 0.359 | 0.264 | false | true | IGHV4 | IGLV1 | Lambda | null | null | null | null | null |
4i2x | B | A | 0 | E | protein | null | signal-regulatory protein gamma | IMMUNE SYSTEM | 11/23/12 | Crystal structure of Signal Regulatory Protein gamma (SIRP-gamma) in complex with FabOX117 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Nettleship, J.E., Ren, J., Stuart, D.I., Owens, R.J., Oxford Protein Production Facility (OPPF) | 2.48 | X-RAY DIFFRACTION | 0.260 | 0.196 | false | false | IGHV1 | IGKV6 | Kappa | 0.000001 | -8.077442 | AUC | null | TBD |
7kfv | C | D | 0 | B | protein | null | surface glycoprotein | IMMUNE SYSTEM/Viral protein | 10/15/20 | Structural basis for a germline-biased antibody response to SARS-CoV-2 (RBD:C1A-B12 Fab) | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Pan, J., Abraham, J., Clark, L., Clark, S. | 2.102 | X-RAY DIFFRACTION | 0.216 | 0.183 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
4b41 | A | null | 0 | null | null | null | null | IMMUNE SYSTEM | 07/27/12 | Crystal structure of an amyloid-beta binding single chain antibody G7 | LAMA GLAMA | lama glama | null | null | Beringer, D.X., Dorresteijn, B., Rutten, L., Wienk, H., el Khattabi, M., Kroon-Batenburg, L.M.J., Verrips, C.T. | 1.191 | X-RAY DIFFRACTION | 0.1619 | 0.1360 | false | true | IGHV1 | null | null | null | null | null | null | null |
7r4i | E | null | 0 | B | protein | null | spike glycoprotein | VIRAL PROTEIN | 02/08/22 | The SARS-CoV-2 spike in complex with the 2.15 neutralizing nanobody | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; CAMELUS DROMEDARIUS | camelus dromedarius | null | severe acute respiratory syndrome coronavirus2 | Casasnovas, J.M., Melero, R., Arranz, R., Fernandez, L.A. | 3.2 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
3r06 | F | E | 0 | null | null | null | null | IMMUNE SYSTEM | 03/07/11 | Crystal structure of anti-mouse CD3epsilon antibody 2C11 Fab fragment | CRICETULUS MIGRATORIUS | cricetulus migratorius | cricetulus migratorius | null | Shore, D.A., Zhu, X., Wilson, I.A. | 2.5 | X-RAY DIFFRACTION | 0.236 | 0.191 | false | true | IGHV5 | IGKV14 | Kappa | null | null | null | null | null |
6cm3 | T | U | 0 | C | protein | null | envelope glycoprotein gp160 | VIRAL PROTEIN | 03/02/18 | BG505 SOSIP in complex with sCD4, 17b, 8ANC195 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Wang, H., Bjorkman, P.J. | 3.54 | ELECTRON MICROSCOPY | null | null | false | true | unknown | IGKV1 | Kappa | null | null | null | null | null |
7m1h | F | null | 0 | A | protein | null | botulinum neurotoxin a light chain | ANTITOXIN | 03/13/21 | Crystal structure of LC/A-JPU-C10-JPU-D12-JPU-B8-JPU-G3-ciA-F12-ciA-D12 | CLOSTRIDIUM BOTULINUM; VICUGNA PACOS | vicugna pacos | null | clostridium botulinum | Lam, K., Jin, R. | 2.78 | X-RAY DIFFRACTION | 0.249 | 0.217 | false | true | IGHV1 | null | null | null | null | null | null | null |
1a8j | null | H | 0 | L | Hapten | PME | N-L-ALPHA-ASPARTYL L-PHENYLALANINE 1-METHYL ESTER | IMMUNOGLOBULIN | 03/26/98 | IMMUNOGLOBULIN LAMBDA LIGHT CHAIN DIMER (MCG) COMPLEX WITH ASPARTAME | HOMO SAPIENS | null | homo sapiens | homo sapiens | Edmundson, A.B., Manion, C.V. | 2.7 | X-RAY DIFFRACTION | 0.380 | 0.220 | false | false | null | IGLV2 | Lambda | null | null | null | null | null |
6bfq | C | D | 0 | G | protein | null | granulocyte-macrophage colony-stimulating factor | IMMUNE SYSTEM | 10/26/17 | The mechanism of GM-CSF inhibition by human GM-CSF auto-antibodies | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Dhagat, U., Hercus, T.R., Broughton, S.E., Nero, T.L., Lopez, A.F., Parker, M.W. | 2.6 | X-RAY DIFFRACTION | 0.264 | 0.230 | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
7niv | C | B | 0 | A | protein | null | isoform 2 of phosphatidylcholine translocator abcb4 | PROTEIN TRANSPORT | 02/14/21 | Nanodisc reconstituted human ABCB4 in complex with 4B1-Fab and QA2-Fab (phosphatidylcholine-bound, occluded conformation) | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Nosol, K., Locher, K.P. | 3.6 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
5gzr | H | L | 0 | null | null | null | null | VIRUS | 10/01/16 | Zika virus E protein complexed with a neutralizing antibody Z23-Fab | HOMO SAPIENS; ZIKA VIRUS | homo sapiens | homo sapiens | null | Gao, G.G., Shi, Y., Peng, R., Liu, S. | 9.4 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
6sne | F | E | 0 | N | peptide | null | envelope glycoprotein gp160 | IMMUNE SYSTEM | 08/23/19 | crystal structure of LN01 Fab in complex with an HIV-1 gp41 peptide | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Caillat, C., Pinto, D., Corti, D., Fenwick, C., Pantaleo, G., Weissenhorn, W. | 3.9 | X-RAY DIFFRACTION | 0.261 | 0.218 | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
1u8k | B | A | 0 | C | peptide | null | gp41 peptide | IMMUNE SYSTEM | 08/06/04 | Crystal structure of the HIV-1 Cross Neutralizing Monoclonal Antibody 2F5 in complex with gp41 Peptide LELDKWASL | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Bryson, S., Julien, J.-P., Pai, E.F. | 2.24 | X-RAY DIFFRACTION | 0.246 | 0.215 | false | false | IGHV2 | IGKV1 | Kappa | null | null | null | null | null |
4hg4 | V | W | 0 | G | protein | null | hemagglutinin ha2 | VIRAL PROTEIN/IMMUNE SYSTEM | 10/06/12 | Crystal structure of Fab 2G1 in complex with a H2N2 influenza virus hemagglutinin | INFLUENZA A VIRUS; HOMO SAPIENS | homo sapiens | homo sapiens | influenza a virus | Xu, R., Wilson, I.A. | 3.2 | X-RAY DIFFRACTION | 0.302 | 0.249 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
7zfa | E | F | 0 | B | protein | null | spike protein s1 | VIRAL PROTEIN | 04/01/22 | SARS-CoV-2 Omicron RBD in complex with Omi-6 and COVOX-150 Fabs | Homo sapiens; Severe acute respiratory syndrome coronavirus 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Zhou, D., Huo, J., Ren, J., Stuart, D.I. | 4.24 | X-RAY DIFFRACTION | 0.272 | 0.237 | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
7d0c | G | F | 0 | C | protein | null | spike glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 09/09/20 | S protein of SARS-CoV-2 in complex bound with P5A-3A1 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Yan, R.H., Wang, R.K., Yu, J.F., Zhang, Y.Y., Liu, N., Wang, H.W., Wang, X.Q., Zhang, L.Q., Zhou, Q. | 3.4 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
2osl | A | B | 0 | Q | peptide | null | b-lymphocyte antigen cd20 | Immune System | 02/06/07 | Crystal structure of Rituximab Fab in complex with an epitope peptide | HOMO SAPIENS, MUS MUSCULUS; SYNTHETIC CONSTRUCT | homo sapiens, mus musculus | homo sapiens, mus musculus | null | Du, J., Zhong, C., Ding, J. | 2.6 | X-RAY DIFFRACTION | 0.296 | 0.239 | false | true | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
5ucb | H | L | 0 | B | protein | null | histone chaperone asf1 | IMMUNE SYSTEM | 12/22/16 | Structure of antigen-Fab complex with engineered switch residue region. | HOMO SAPIENS; SACCHAROMYCES CEREVISIAE (STRAIN ATCC 204508 / S288C) | homo sapiens | homo sapiens | saccharomyces cerevisiae (strain atcc 204508 /s288c) | Bailey, L.J., Kossiakoff, A.A., Chaperone-Enabled Studies of Epigenetic Regulation Enzymes (CEBS) | 1.521 | X-RAY DIFFRACTION | 0.169 | 0.138 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
3o45 | H | L | 0 | P | peptide | null | fusion glycoprotein f1 | IMMUNE SYSTEM/VIRAL PROTEIN | 07/26/10 | Crystal Structure of 101F Fab Bound to 17-mer Peptide Epitope | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | null | McLellan, J.S., Chen, M., Chang, J.S., Yang, Y., Kim, A., Graham, B.S., Kwong, P.D. | 2.872 | X-RAY DIFFRACTION | 0.254 | 0.200 | false | true | IGHV8 | IGKV3 | Kappa | null | null | null | null | null |
5nm0 | D | null | 0 | null | null | null | null | IMMUNE SYSTEM | 04/05/17 | Nb36 Ser85Cys with Hg, crystal form 1 | LAMA GLAMA | lama glama | null | null | Hansen, S.B., Andersen, K.R., Laursen, N.S., Andersen, G.R. | 1.5 | X-RAY DIFFRACTION | 0.211 | 0.189 | false | true | IGHV1 | null | null | null | null | null | null | null |
4ydl | H | L | 0 | G | protein | null | envelope glycoprotein gp160,envelope glycoprotein gp160 | IMMUNE SYSTEM | 02/22/15 | Crystal structure of broadly and potently neutralizing antibody C38-VRC18.02 in complex with HIV-1 clade AE strain 93TH057gp120 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Zhou, T., Srivatsan, S., Kwong, P.D. | 1.8 | X-RAY DIFFRACTION | 0.207 | 0.174 | false | true | unknown | IGKV3 | Kappa | null | null | null | null | null |
2uud | H | L | 0 | S | peptide | null | nq10-1.12 anti-phox antibody | IMMUNE SYSTEM | 03/02/07 | Crystal structure of the TEPC15-Vk45.1 anti-2-phenyl-5-oxazolone NQ10- 1.12 scFv in complex with the hapten | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Scotti, C., Gherardi, E. | 2.9 | X-RAY DIFFRACTION | 0.297 | 0.228 | false | true | IGHV7 | IGKV1 | Kappa | null | null | null | null | null |
7mlv | H | I | 0 | C | protein | null | glycine receptor alpha 1 | MEMBRANE PROTEIN, SIGNALING PROTEIN | 04/29/21 | Cryo-EM reveals partially and fully assembled native glycine receptors,homomeric tetramer | RATTUS NORVEGICUS; SUS SCROFA | rattus norvegicus | rattus norvegicus | sus scrofa | Zhu, H., Gouaux, E. | 4.1 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV6 | Kappa | null | null | null | null | null |
7bc6 | B | null | 0 | A | protein | null | proton-coupled folate transporter | MEMBRANE PROTEIN | 12/18/20 | Cryo-EM structure of the outward open proton coupled folate transporter at pH 7.5 | GALLUS GALLUS; LAMA GLAMA | lama glama | null | gallus gallus | Parker, J.L., Deme, J.C., Lea, S.M., Newstead, S. | 3.2 | ELECTRON MICROSCOPY | null | null | false | false | IGHV3 | null | null | null | null | null | null | null |
7k8n | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 09/27/20 | Crystal structure of an anti-SARS-CoV-2 human neutralizing antibody Fab fragment, C102 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Jette, C.A., Barnes, C.O., Bjorkman, P.J. | 1.65 | X-RAY DIFFRACTION | 0.207 | 0.197 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
4org | C | D | 0 | null | null | null | null | IMMUNE SYSTEM | 02/11/14 | Crystal structure of human Fab CAP256-VRC26.04, a potent V1V2-directed HIV-1 neutralizing antibody | HOMO SAPIENS | homo sapiens | homo sapiens | null | Gorman, J., Doria-Rose, N.A., Schramm, C.A., Moore, P.L., Mascola, J.R., Shapiro, L., Morris, L., Kwong, P.D. | 3.121 | X-RAY DIFFRACTION | 0.289 | 0.275 | false | true | IGHV3 | IGLV1 | Lambda | null | null | null | null | null |
3wii | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 09/12/13 | Crystal structure of the Fab fragment of B2212A, a murine monoclonal antibody specific for the third fibronectin domain (Fn3) of human ROBO1. | MUS MUSCULUS | mus musculus | mus musculus | null | Nakayama, T., Mizohata, E., Yamashita, T., Nagatoishi, S., Nakakido, M., Iwanari, H., Mochizuki, Y., Kado, Y., Yokota, Y., Sato, R., Tsumoto, K., Fujitani, H., Kodama, T., Hamakubo, T., Inoue, T. | 1.6 | X-RAY DIFFRACTION | 0.230 | 0.185 | false | false | IGHV1 | IGKV10 | Kappa | null | null | null | null | null |
7dw9 | S | s | 0 | A | protein | null | guanine nucleotide-binding protein g(s) subunit alphaisoforms short | MEMBRANE PROTEIN | 01/15/21 | Cryo-EM structure of human V2 vasopressin receptor in complex with an Gs protein | HOMO SAPIENS; RATTUS NORVEGICUS; BOS TAURUS; SYNTHETIC CONSTRUCT; SYNTHETIC CONSTRUCT | synthetic construct | null | homo sapiens | Zhou, F., Jiang, Y. | 2.6 | ELECTRON MICROSCOPY | null | null | true | true | unknown | unknown | unknown | null | null | null | null | null |
7m7j | C | D | 0 | A | protein | null | eryai | BIOSYNTHETIC PROTEIN/IMMUNE SYSTEM | 03/28/21 | 6-Deoxyerythronolide B synthase (DEBS) module 1 in complex with antibody fragment 1B2: ""turnstile closed"" state (TE-free) | SACCHAROPOLYSPORA ERYTHRAEA; HOMO SAPIENS | homo sapiens | homo sapiens | saccharopolyspora erythraea | Cogan, D.P., Zhang, K., Chiu, W., Khosla, C. | 4.3 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV2 | Kappa | null | null | null | null | null |
4uta | H | L | 0 | B | protein | null | envelope glycoprotein e | IMMUNE SYSTEM-VIRAL PROTEIN COMPLEX | 07/18/14 | Crystal structure of dengue 2 virus envelope glycoprotein in complex with the Fab fragment of the broadly neutralizing human antibody EDE1 C8 | HOMO SAPIENS; DENGUE VIRUS 2 | homo sapiens | homo sapiens | dengue virus 2 | Rouvinski, A., Guardado-Calvo, P., Barba-Spaeth, G., Duquerroy, S., Vaney, M.C., Rey, F.A. | 3.0 | X-RAY DIFFRACTION | 0.2477 | 0.2128 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
5yoy | I | F | 0 | A | protein | null | tumor necrosis factor | IMMUNE SYSTEM | 10/31/17 | Crystal structure of the human tumor necrosis factor in complex with golimumab Fv | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Ono, M., Horita, S., Sato, Y., Nomura, Y., Iwata, S., Nomura, N. | 2.727 | X-RAY DIFFRACTION | 0.234 | 0.190 | false | true | IGHV3 | IGKV3 | Kappa | 0 | -14.658431 | Unknown | null | TBD |
7lxz | F | C | 0 | B | protein | null | spike glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 03/05/21 | SARS-CoV-2 S/S2M11/S2L28 Global Refinement | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | McCallum, M., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 2.6 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
5vpl | D | C | 0 | A | protein | null | der f 1 variant | HYDROLASE/IMMUNE SYSTEM | 05/05/17 | CRYSTAL STRUCTURE OF DER F 1 COMPLEXED WITH FAB 4C1 | MUS MUSCULUS; DERMATOPHAGOIDES FARINAE | mus musculus | mus musculus | dermatophagoides farinae | Chruszcz, M., Vailes, L.D., Chapman, M.D., Pomes, A., Minor, W. | 1.9 | X-RAY DIFFRACTION | 0.194 | 0.152 | false | true | IGHV3 | IGKV14 | Kappa | 0 | -10.599564 | ITC | null | TBD |
7wq4 | N | null | 0 | A | B | protein | protein | NA | NA | engineered guanine nucleotide-binding protein g(q) subunitalpha | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | MEMBRANE PROTEIN | 01/24/22 | Galanin-bound galanin receptor 2 in complex with Gq | HOMO SAPIENS; RATTUS; LAMA GLAMA; BOS TAURUS; SYNTHETIC CONSTRUCT | lama glama | null | homo sapiens | rattus | Duan, J., Shen, D.D., Xu, H.E., Zhang, Y., Jiang, Y. | 2.6 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | null | null | null | null | null | null | null |
6yxg | H | h | 0 | A | protein | null | adiponectin receptor protein 2 | MEMBRANE PROTEIN | 05/01/20 | Cryogenic human adiponectin receptor 2 (ADIPOR2) with Tb-XO4 ligand determined by Serial Crystallography (SSX) using CrystalDirect | HOMO SAPIENS | homo sapiens | null | homo sapiens | Healey, R.D., Basu, S., Humm, A.S., Leyrat, C., Dupeux, F., Pica, A., Granier, S., Marquez, J.A. | 3.01 | X-RAY DIFFRACTION | 0.252 | 0.213 | true | true | unknown | unknown | unknown | null | null | null | null | null |
7f1o | E | null | 0 | A | B | protein | protein | NA | NA | guanine nucleotide-binding protein g(s) subunit alphaisoforms short,isoform gnas-2 of guanine nucleotide-binding protein g(s) subunit alpha isoforms short | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | MEMBRANE PROTEIN | 06/09/21 | Cryo-EM structure of the GDP-bound dopamine receptor 1 and mini-Gs complex with Nb35 | HOMO SAPIENS; SYNTHETIC CONSTRUCT | synthetic construct | null | homo sapiens | homo sapiens | Xiao, T., Zheng, S. | 3.13 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | null | null | null | null | null | null | null |
6oz6 | G | null | 0 | C | protein | null | phospho-n-acetylmuramoyl-pentapeptide-transferase | MEMBRANE PROTEIN/TRANSFERASE | 05/15/19 | Crystal structure of MraY bound to 3'-hydroxymureidomycin A | LAMA GLAMA; AQUIFEX AEOLICUS (STRAIN VF5) | lama glama | null | aquifex aeolicus (strain vf5) | Mashalidis, E.H., Lee, S.Y. | 3.7 | X-RAY DIFFRACTION | 0.301 | 0.257 | false | true | IGHV1 | null | null | null | null | null | null | null |
7lf0 | D | E | 0 | B | protein | null | arginase-1 | HYDROLASE/IMMUNE SYSTEM | 01/15/21 | Trimeric human Arginase 1 in complex with mAb2 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Gomez-Llorente, Y., Scapin, G., Palte, R.L. | 3.68 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
7om5 | A | null | 0 | null | null | null | null | IMMUNE SYSTEM | 05/21/21 | Anti-EGFR nanobody EgB4 | LAMA GLAMA | lama glama | null | null | Zeronian, M.R., Janssen, B.J.C. | 1.48 | X-RAY DIFFRACTION | 0.205 | 0.177 | false | true | IGHV1 | null | null | null | null | null | null | null |
6aj9 | D | E | 0 | A | protein | null | capsid protein vp1 | VIRUS | 08/27/18 | The structure of Enterovirus D68 mature virion in complex with Fab 15C5 and 11G1 | MUS MUSCULUS; ENTEROVIRUS D68 | mus musculus | mus musculus | enterovirus d68 | Zheng, Q.B., Zhu, R., Xu, L.F., He, M.Z., Yan, X.D., Cheng, T., Li, S.W. | 3.5 | ELECTRON MICROSCOPY | null | null | false | false | IGHV1 | IGKV8 | Kappa | null | null | null | null | null |
6gjs | C | null | 0 | A | protein | null | cystic fibrosis transmembrane conductance regulator | IMMUNE SYSTEM | 05/16/18 | Human NBD1 of CFTR in complex with nanobodies D12 and T4 | HOMO SAPIENS; LAMA GLAMA | lama glama | null | homo sapiens | Sigoillot, M., Overtus, M., Grodecka, M., Scholl, D., Garcia-Pino, A., Laeremans, T., He, L., Pardon, E., Hildebrandt, E., Urbatsch, I., Steyaert, J., Riordan, J.R., Govaerts, C. | 1.95 | X-RAY DIFFRACTION | 0.212 | 0.177 | false | true | IGHV1 | null | null | null | null | null | null | null |
7zmm | K | null | 0 | A | protein | null | atp-dependent dna helicase q5 | HYDROLASE | 04/19/22 | Crystal structure of human RECQL5 helicase APO form in complex with engineered nanobody (Gluebody) G2-001 | Homo sapiens; Lama glama | lama glama | null | homo sapiens | Ye, M., Makola, M., Newman, J.A., Fairhead, M., MacLean, E., Krojer, T., Aitkenhead, H., Bountra, C., Gileadi, O., von Delft, F. | 2.5 | X-RAY DIFFRACTION | 0.281 | 0.240 | false | true | IGHV1 | null | null | null | null | null | null | null |
4fqk | E | F | 0 | C | protein | null | hemagglutinin ha1 | VIRAL PROTEIN/IMMUNE SYSTEM | 06/25/12 | Influenza B/Brisbane/60/2008 hemagglutinin Fab CR8059 complex | INFLUENZA B VIRUS; HOMO SAPIENS | homo sapiens | homo sapiens | influenza b virus | Dreyfus, C., Laursen, N.S., Wilson, I.A. | 5.65 | X-RAY DIFFRACTION | 0.324 | 0.306 | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
3bjl | null | B | 0 | null | null | null | null | IMMUNOGLOBULIN | 05/26/95 | LOC, A LAMBDA 1 TYPE LIGHT-CHAIN DIMER (BENCE-JONES PROTEIN) CRYSTALLIZED IN AMMONIUM SULFATE | HOMO SAPIENS | null | homo sapiens | null | Schiffer, M., Huang, D.B. | 2.3 | X-RAY DIFFRACTION | unknown | unknown | false | false | null | IGLV1 | Lambda | null | null | null | null | null |
7cj2 | C | D | 0 | A | protein | null | chitinase 3-like 1 (cartilage glycoprotein-39), isoformcra_a | IMMUNE SYSTEM | 07/09/20 | Crystal structure of the Fab antibody complexed with human YKL-40 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Choi, S., Na, J.H., Lee, S.J., Woo, J.R., Kim, D.Y., Hong, J.T., Lee, W.K. | 2.7 | X-RAY DIFFRACTION | 0.269 | 0.212 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6nmr | J | K | 0 | M | protein | null | tyrosine-protein phosphatase non-receptor type substrate 1 | IMMUNE SYSTEM | 01/11/19 | Blocking Fab 119 anti-SIRP-alpha antibody in complex with SIRP-alpha Variant 1 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Wibowo, A.S., Carter, J.J., Sim, J. | 2.42 | X-RAY DIFFRACTION | 0.323 | 0.289 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
4yga | F | null | 0 | E | protein | null | calmodulin-domain protein kinase 1 | METAL BINDING PROTEIN | 02/26/15 | CDPK1, from Toxoplasma gondii, bound to inhibitory VHH-1B7 | VICUGNA PACOS; TOXOPLASMA GONDII | vicugna pacos | null | toxoplasma gondii | Knockenhauer, K.E., Schwartz, T.U. | 2.94 | X-RAY DIFFRACTION | 0.262 | 0.226 | false | true | IGHV1 | null | null | null | null | null | null | null |
4unt | null | G | 0 | null | null | null | null | IMMUNE SYSTEM | 05/30/14 | Induced monomer of the Mcg variable domain | HOMO SAPIENS | null | homo sapiens | null | Brumshtein, B., Esswein, S.R., Landau, M., Ryan, C.M., Whitelegge, J.P., Phillips, M.L., Cascio, D., Sawaya, M.R., Eisenberg, D.S. | 2.7 | X-RAY DIFFRACTION | 0.28925 | 0.24328 | false | true | null | IGLV2 | Lambda | null | null | null | null | null |
7q6e | E | F | 0 | B | protein | null | spike glycoprotein | VIRAL PROTEIN | 11/07/21 | Beta049 fab in complex with SARS-CoV2 beta-Spike glycoprotein, The Beta mAb response underscores the antigenic distance to other SARS-CoV-2 variants | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Duyvesteyn, H.M.E., Ren, J., Stuart, D.I. | 2.7 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
1fl5 | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 08/11/00 | THE UNLIGANDED GERMLINE PRECURSOR TO THE SULFIDE OXIDASE CATALYTIC ANTIBODY 28B4. | MUS MUSCULUS; HOMO SAPIENS | homo sapiens | mus musculus | null | Yin, J., Mundorff, E.C., Yang, P.L., Wendt, K.U., Hanway, D., Stevens, R.C., Schultz, P.G. | 2.1 | X-RAY DIFFRACTION | 0.268 | 0.226 | false | true | IGHV7 | IGKV1 | Kappa | null | null | null | null | null |
6nnj | H | L | 0 | G | protein | null | envelope glycoprotein gp120 | IMMUNE SYSTEM | 01/15/19 | Crystal Structure of HIV-1 BG505 SOSIP.664 Prefusion Env Trimer Bound to CH31 scFv in Complex with Crystallization Chaperones 3H109L Fab and 35O22 scFv at 3.1 Angstrom | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Lai, Y.-T., Kwong, P.D. | 2.6 | X-RAY DIFFRACTION | 0.293 | 0.248 | false | true | IGHV4 | unknown | unknown | null | null | null | null | null |
6bf7 | C | D | 0 | A | protein | null | insulin-degrading enzyme | HYDROLASE/IMMUNE SYSTEM | 10/26/17 | Cryo-EM structure of human insulin degrading enzyme in complex with FAB H11-E heavy chain, FAB H11-E light chain | HOMO SAPIENS; MUS MUSCULUS | mus musculus, homo sapiens | mus musculus, homo sapiens | homo sapiens | Liang, W.G., Zhang, Z., Bailey, L.J., Kossiakoff, A.A., Tan, Y.Z., Wei, H., Carragher, B., Potter, S.C., Tang, W.J. | 6.5 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
5itf | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 03/16/16 | Cetuximab Fab in complex with 2-bromophenylalanine meditope variant | MUS MUSCULUS, HOMO SAPIENS; SYNTHETIC CONSTRUCT | mus musculus, homo sapiens | mus musculus, homo sapiens | null | Bzymek, K.P., Williams, J.C. | 2.51 | X-RAY DIFFRACTION | 0.223 | 0.184 | false | true | IGHV2 | IGKV5 | Kappa | 0.000002 | -7.837211 | Unknown | null | TBD |
5tru | h | l | 0 | c | protein | null | unknown | IMMUNE SYSTEM | 10/27/16 | Structure of the first-in-class checkpoint inhibitor Ipilimumab bound to human CTLA-4 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Ramagopal, U.A., Liu, W., Garrett-Thomson, S.C., Yan, Q., Srinivasan, M., Wong, S.C., Bell, A., Mankikar, S., Rangan, V.S., Deshpande, S., Bonanno, J.B., Korman, A.J., Almo, S.C. | 3.0 | X-RAY DIFFRACTION | 0.268 | 0.204 | false | false | IGHV3 | IGKV3 | Kappa | 0 | -10.879429 | Unknown | null | TBD |
3fzu | C | D | 0 | null | null | null | null | IMMUNE SYSTEM | 01/26/09 | IgG1 Fab characterized by H/D exchange | HOMO SAPIENS | homo sapiens | homo sapiens | null | Arndt, J., Houde, D., Domeier, W., Berkowitz, S., Engen, J.R. | 2.5 | X-RAY DIFFRACTION | 0.261 | 0.210 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
2kqm | null | A | 12 | null | null | null | null | IMMUNE SYSTEM | 11/11/09 | Solution structure of the KI O18/O8 Y87H immunoglobulin light chain variable domain | HOMO SAPIENS | null | homo sapiens | null | Volkman, B.F., Peterson, F.C., Ramirez-Alvarado, M., Baden, E.M. | NOT | SOLUTION NMR | null | null | false | true | null | IGKV1 | Kappa | null | null | null | null | null |
7whi | E | null | 0 | C | protein | null | spike glycoprotein | VIRAL PROTEIN | 12/30/21 | The state 2 complex structure of Omicron spike with Bn03 (2-up RBD, 4 nanobodies) | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | null | severe acute respiratory syndrome coronavirus2 | Zhan, W.Q., Zhang, X., Chen, Z.G., Sun, L. | 2.93 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | null | null | null | null | null | null | null |
7bsd | A | B | 0 | G | protein | null | ns1c | IMMUNE SYSTEM/VIRAL PROTEIN | 03/30/20 | Complex structure of 1G5.3 Fab bound to ZIKV NS1c | HOMO SAPIENS; ZIKA VIRUS | homo sapiens | homo sapiens | zika virus | Song, H., Qi, J., Gao, F.G. | 2.53 | X-RAY DIFFRACTION | 0.239 | 0.221 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
3fo2 | H | L | 0 | H | Hapten | BZH | 5-[(2-AMINO-1H-BENZIMIDAZOL-6-YL)AMINO]-5-OXOPENTANOIC ACID | IMMUNE SYSTEM | 12/27/08 | Crystal structure of hapten complex of catalytic elimination antibody 13G5 (Glu(L39)Gln mutant) | MUS MUSCULUS, HOMO SAPIENS | mus musculus, homo sapiens | mus musculus, homo sapiens | mus musculus, homo sapiens | Debler, E.W., Wilson, I.A. | 2.18 | X-RAY DIFFRACTION | 0.256 | 0.201 | false | true | IGHV2 | IGKV1 | Kappa | null | null | null | null | null |
6niu | M | N | 0 | E | protein | null | envelope protein e | Viral protein/IMMUNE SYSTEM | 12/31/18 | Crystal structure of a human anti-ZIKV-DENV neutralizing antibody MZ4 in complex with ZIKV E glycoprotein | HOMO SAPIENS; ZIKA VIRUS (ISOLATE ZIKV/HUMAN/FRENCH POLYNESIA/10087PF/2013) | homo sapiens | homo sapiens | zika virus (isolate zikv/human/frenchpolynesia/10087pf/2013) | Sankhala, R.S., Dussupt, V., Donofrio, G., Choe, M., Modjarrad, K., Michael, N.L., Krebs, S.J., Joyce, M.G. | 4.303 | X-RAY DIFFRACTION | 0.359 | 0.264 | false | true | IGHV4 | IGLV1 | Lambda | null | null | null | null | null |
6ocb | H | L | 0 | A | protein | null | hemagglutinin | IMMUNE SYSTEM | 03/22/19 | Crystal structure of FluA-20 Fab in complex with the head domain of H3 (A/Hong Kong/1/1968) | HOMO SAPIENS; INFLUENZA A VIRUS | homo sapiens | homo sapiens | influenza a virus | Wilson, I.A., Lang, S. | 2.1 | X-RAY DIFFRACTION | 0.239 | 0.202 | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
7ps0 | B | C | 0 | A | protein | null | surface glycoprotein | VIRAL PROTEIN | 09/22/21 | Crystal structure of the receptor binding domain of SARS-CoV-2 beta variant spike glycoprotein in complex with beta-24 Fabs | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Zhou, D., Ren, J., Stuart, D.I. | 2.92 | X-RAY DIFFRACTION | 0.271 | 0.222 | false | true | IGHV4 | IGLV2 | Lambda | null | null | null | null | null |
6bfq | A | B | 0 | I | protein | null | granulocyte-macrophage colony-stimulating factor | IMMUNE SYSTEM | 10/26/17 | The mechanism of GM-CSF inhibition by human GM-CSF auto-antibodies | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Dhagat, U., Hercus, T.R., Broughton, S.E., Nero, T.L., Lopez, A.F., Parker, M.W. | 2.6 | X-RAY DIFFRACTION | 0.264 | 0.230 | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
1k6q | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 10/17/01 | Crystal structure of antibody Fab fragment D3 | MUS MUSCULUS | mus musculus | mus musculus | null | Faelber, K., Kelley, R.F., Kirchhofer, D., Muller, Y.A. | 2.4 | X-RAY DIFFRACTION | 0.298 | 0.225 | false | true | IGHV14 | IGKV14 | Kappa | null | null | null | null | null |
3duu | D | C | 0 | D | carbohydrate | KDO | 3-DEOXY-D-MANNO-OCT-2-ULOSONIC ACID | IMMUNE SYSTEM | 07/17/08 | Crystal structure of SAG506-01, orthorhombic, twinned, crystal 2 | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Brooks, C.L., Blackler, R.J., Gerstenbruch, S., Kosma, P., Muller-Loennies, S., Brade, H., Evans, S.V. | 1.95 | X-RAY DIFFRACTION | 0.217 | 0.194 | false | true | IGHV7 | IGKV8 | Kappa | null | null | null | null | null |
3wd5 | H | L | 0 | A | protein | null | tumor necrosis factor | IMMUNE SYSTEM | 06/06/13 | Crystal structure of TNFalpha in complex with Adalimumab Fab fragment | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Hu, S., Liang, S.Y., Guo, Y.J., Lou, Z.Y. | 3.101 | X-RAY DIFFRACTION | 0.275 | 0.187 | false | true | IGHV3 | IGKV1 | Kappa | 0 | -13.559634 | SPR | null | TBD |
7nil | F | null | 0 | A | protein | null | polymerase acidic protein | VIRAL PROTEIN | 02/12/21 | 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8190 core | INFLUENZA A VIRUS (A/BREVIG MISSION/1/1918(H1N1)); STAPHYLOCOCCUS AUREUS; CAMELIDAE MIXED LIBRARY; SYNTHETIC CONSTRUCT | camelidae mixed library | null | influenza a virus (a/brevigmission/1/1918(h1n1)) | Keown, J.R., Carrique, L., Fodor, E., Grimes, J.M. | 5.01 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
7ndf | D | null | 0 | A | protein | null | lipid a abc transporter atp-binding protein/permease msba | PROTEIN BINDING | 02/01/21 | Crystal structure of nanobody Nb_MsbA#1 in complex with the nucleotide binding domain of MsbA | VICUGNA PACOS; ESCHERICHIA COLI | vicugna pacos | null | escherichia coli | Meier, G., Seeger, M. | 2.1 | X-RAY DIFFRACTION | 0.244 | 0.205 | false | true | IGHV1 | null | null | null | null | null | null | null |
6d01 | E | F | 0 | J | peptide | null | nanp5 | IMMUNE SYSTEM | 04/09/18 | Crystal structure of 1210 Fab in complex with circumsporozoite protein NANP5 | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | plasmodium falciparum | Scally, S.W., Bosch, A., Imkeller, K., Wardemann, H., Julien, J.P. | 3.2 | X-RAY DIFFRACTION | 0.227 | 0.204 | false | true | IGHV3 | IGKV1 | Kappa | 0 | -8.927114 | Unknown | null | TBD |
4ocl | F | null | 0 | E | D | protein | protein | NA | NA | 26s proteasome regulatory subunit rpn11 | 26s proteasome regulatory subunit rpn8 | HYDROLASE, PROTEIN BINDING | 01/09/14 | Crystal Structure of the Rpn8-Rpn11 MPN domain heterodimer, crystal form Ia | SACCHAROMYCES CEREVISIAE; LAMA GLAMA | lama glama | null | saccharomyces cerevisiae | saccharomyces cerevisiae | Pathare, G.R., Bracher, A. | 2.4 | X-RAY DIFFRACTION | 0.252 | 0.195 | false | true | IGHV1 | null | null | null | null | null | null | null |
7nx7 | A | B | 0 | E | protein | null | spike protein s1 | VIRAL PROTEIN/IMMUNE SYSTEM | 03/17/21 | Crystal structure of the K417N mutant receptor binding domain of SARS-CoV-2 Spike glycoprotein in complex with COVOX-222 and EY6A Fabs | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Zhou, D., Ren, J., Stuart, D. | 2.3 | X-RAY DIFFRACTION | 0.239 | 0.208 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.