pdb stringlengths 4 4 | Hchain stringclasses 59
values | Lchain stringclasses 60
values | model int64 0 76 | antigen_chain stringclasses 386
values | antigen_type stringclasses 24
values | antigen_het_name stringclasses 240
values | antigen_name stringlengths 1 396 ⌀ | short_header stringclasses 448
values | date stringlengths 8 8 | compound stringlengths 4 243 | organism stringlengths 3 175 ⌀ | heavy_species stringclasses 121
values | light_species stringclasses 67
values | antigen_species stringclasses 937
values | authors stringlengths 6 762 | resolution stringlengths 1 8 | method stringclasses 10
values | r_free stringclasses 354
values | r_factor stringclasses 342
values | scfv bool 2
classes | engineered bool 2
classes | heavy_subclass stringclasses 14
values | light_subclass stringclasses 35
values | light_ctype stringclasses 3
values | affinity float64 0 0 ⌀ | delta_g float64 -16.91 -5.04 ⌀ | affinity_method stringclasses 11
values | temperature float64 4 37 ⌀ | pmid stringclasses 157
values |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
6s8j | P | O | 0 | C | protein | null | envelope glycoprotein 1 | VIRAL PROTEIN | 07/10/19 | Structure of ZEBOV GP in complex with 5T0180 antibody | HOMO SAPIENS; EBOLA VIRUS | homo sapiens | homo sapiens | ebola virus | Diskin, R., Cohen-Dvashi, H. | 2.91 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGLV1 | Lambda | null | null | null | null | null |
7r1z | E | null | 0 | A | protein | null | activity-regulated cytoskeleton-associated protein | SIGNALING PROTEIN | 02/03/22 | C-terminal domain of hArc in complex with nanobodies H11 and C11, collapsed crystal form | VICUGNA PACOS; RATTUS NORVEGICUS | vicugna pacos | null | rattus norvegicus | Markusson, S., Kursula, P. | 1.94 | X-RAY DIFFRACTION | 0.243 | 0.197 | false | true | IGHV1 | null | null | null | null | null | null | null |
6ca6 | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 01/29/18 | Crystal structure of PCT64_35S, a broadly neutralizing anti-HIV antibody. | HOMO SAPIENS | homo sapiens | homo sapiens | null | Murrell, S., Wilson, I.A. | 2.43 | X-RAY DIFFRACTION | 0.245 | 0.201 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
7mbx | N | null | 0 | A | B | G | protein | protein | protein | NA | NA | NA | guanine nucleotide-binding protein g(s) subunit alphaisoforms short | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | guanine nucleotide-binding protein g(i)/g(s)/g(o) subunitgamma-2 | MEMBRANE PROTEIN/SIGNALING PROTEIN | 04/01/21 | Human Cholecystokinin 1 receptor (CCK1R) Gs complex | HOMO SAPIENS; RATTUS NORVEGICUS; LAMA GLAMA; SYNTHETIC CONSTRUCT | lama glama | null | homo sapiens | rattus norvegicus | homo sapiens | Mobbs, J.I., Belousoff, M.J., Danev, R., Thal, D.M., Sexton, P.M. | 1.95 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | null | null | null | null | null | null | null |
6uda | G | H | 0 | E | protein | null | ch505.n279k.g458y.sosip.664 gp120 | VIRAL PROTEIN/Immune System | 09/19/19 | Cryo-EM structure of CH235UCA bound to Man5-enriched CH505.N279K.G458Y.SOSIP.664 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Henderson, R., Acharya, P. | 4.2 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
2eh8 | H | L | 0 | P | peptide | null | pres1/pres2/surface protein | IMMUNE SYSTEM | 03/05/07 | Crystal structure of the complex of humanized KR127 fab and PRES1 peptide epitope | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | null | Chi, S.-W., Kim, S.-J., Maeng, C.-Y., Hong, H.J., Ryu, S.-E. | 2.6 | X-RAY DIFFRACTION | 0.258 | 0.193 | false | true | IGHV1 | IGKV1 | Kappa | 0 | -11.29 | Other | 37 | 17517649 |
7n28 | C | D | 0 | A | protein | null | envelope glycoprotein gp120 | IMMUNE SYSTEM/VIRAL PROTEIN | 05/28/21 | Cryo-EM structure of broadly neutralizing V2-apex-targeting antibody J033 in complex with HIV-1 Env | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS; MACACA MULATTA | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Zhou, T., Gao, F. | 4.2 | ELECTRON MICROSCOPY | null | null | false | true | unknown | IGKV1 | Kappa | null | null | null | null | null |
5tqa | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 10/23/16 | Crystal Structure of DH270.6 (unliganded) from the DH270 Broadly Neutralizing N332-Glycan Dependent Lineage | HOMO SAPIENS | homo sapiens | homo sapiens | null | Fera, D., Harrison, S.C. | 2.723 | X-RAY DIFFRACTION | 0.201 | 0.185 | false | true | IGHV1 | IGLV2 | Lambda | null | null | null | null | null |
5wk2 | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 07/24/17 | CRYSTAL STRUCTURE OF ANTI-CCL17 ANTIBODY M116 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Teplyakov, A., Obmolova, G., Gilliland, G.L. | 1.5 | X-RAY DIFFRACTION | 0.208 | 0.180 | false | true | IGHV5 | IGKV4 | Kappa | null | null | null | null | null |
4ios | G | null | 0 | B | protein | null | bpp | VIRAL PROTEIN | 01/08/13 | Structure of phage TP901-1 RBP (ORF49) in complex with nanobody 11. | LACTOCOCCUS PHAGE TP901-1; LAMA GLAMA | lama glama | null | lactococcus phage tp901-1 | Desmyter, A., Farenc, C., Mahony, J., Spinelli, S., Bebeacua, C., Blangy, S., Veesler, D., van Sinderen, D., Cambillau, C. | 2.4 | X-RAY DIFFRACTION | 0.227 | 0.201 | false | true | IGHV1 | null | null | null | null | null | null | null |
6vmk | K | J | 0 | N | protein | null | fab y49r light chain | HYDROLASE/IMMUNE SYSTEM | 01/28/20 | Crystal structure of human Complement Factor D with anti-Factor D Fab 20D12 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Wu, P., Harris, S.F., Eigenbrot, C. | 3.01 | X-RAY DIFFRACTION | 0.215 | 0.174 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
6k5f | E | F | 0 | B | protein | null | h(+)/cl(-) exchange transporter clca | MEMBRANE PROTEIN | 05/28/19 | Crystal structure of the CLC-ec1 deltaNC in presence of 200 mM NaBr | ESCHERICHIA COLI; MUS MUSCULUS | null | mus musculus | escherichia coli | Park, K., Lim, H.H. | 3.203 | X-RAY DIFFRACTION | 0.300 | 0.236 | false | true | IGHV4 | IGKV4 | Kappa | null | null | null | null | null |
6pz8 | D | K | 0 | F | protein | null | s protein | VIRAL PROTEIN/IMMUNE SYSTEM | 07/31/19 | MERS S0 trimer in complex with variable domain of antibody G2 | MIDDLE EAST RESPIRATORY SYNDROME-RELATED CORONAVIRUS; MUS MUSCULUS | mus musculus | mus musculus | middle east respiratory syndrome-relatedcoronavirus | Bowman, C.A., Pallesen, J., Ward, A.B. | 4.19 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
1eeq | null | B | 0 | null | null | null | null | IMMUNE SYSTEM | 02/01/00 | M4L/Y(27D)D/T94H Mutant of LEN | HOMO SAPIENS | null | homo sapiens | null | Pokkuluri, P.R., Raffen, R., Dieckman, L., Boogaard, C., Stevens, F.J., Schiffer, M. | 1.5 | X-RAY DIFFRACTION | 0.238 | 0.211 | false | true | null | IGKV4 | Kappa | null | null | null | null | null |
7rlz | A | B | 0 | P | peptide | null | peptide from circumsporozoite protein variant vk210 | ANTIMICROBIAL PROTEIN | 07/26/21 | Antibody 2F2 in complex with P. vivax CSP peptide GDRAAGQPAGNGAGGQAA | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | plasmodium vivax | Kucharska, I., Julien, J.P. | 2.27 | X-RAY DIFFRACTION | 0.239 | 0.191 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
1i7z | D | C | 0 | C | Hapten | COC | COCAINE | IMMUNE SYSTEM | 03/12/01 | ANTIBODY GNC92H2 BOUND TO LIGAND | MUS MUSCULUS, HOMO SAPIENS | mus musculus, homo sapiens | mus musculus, homo sapiens | mus musculus, homo sapiens | Larsen, N.A., Wilson, I.A. | 2.3 | X-RAY DIFFRACTION | 0.265 | 0.220 | false | true | IGHV9 | IGKV3 | Kappa | 0 | -8.728352 | Unknown | null | TBD |
6w0c | A | B | 0 | C | protein | null | ph-gated potassium channel kcsa | MEMBRANE PROTEIN | 02/29/20 | Open-gate KcsA soaked in 4 mM BaCl2 | RATTUS NORVEGICUS; STREPTOMYCES LIVIDANS | rattus norvegicus | rattus norvegicus | streptomyces lividans | Rohaim, A., Gong, L., Li, J. | 3.556 | X-RAY DIFFRACTION | 0.248 | 0.200 | false | true | IGHV1 | IGKV5 | Kappa | null | null | null | null | null |
6cde | 3 | 4 | 0 | 1 | protein | null | glycoprotein 41 | VIRAL PROTEIN | 02/08/18 | Cryo-EM structure at 3.8 A resolution of vaccine-elicited antibody vFP20.01 in complex with HIV-1 Env BG505 DS-SOSIP, and antibodies VRC03 and PGT122 | HOMO SAPIENS; HUMAN IMMUNODEFICIENCY VIRUS 1 | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Acharya, P., Xu, K., Liu, K., Carragher, B., Potter, C.S., Kwong, P.D. | 3.8 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
7ldj | E | null | 0 | B | protein | null | spike glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 01/13/21 | SARS-CoV-2 receptor binding domain in complex with WNb-2 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; VICUGNA PACOS | vicugna pacos | null | severe acute respiratory syndrome coronavirus2 | Pymm, P., Dietrich, M.H., Tan, L.L., Adair, A., Tham, W.H. | 2.36 | X-RAY DIFFRACTION | 0.268 | 0.210 | false | true | IGHV1 | null | null | null | null | null | null | null |
7lk9 | C | D | 0 | null | null | null | null | IMMUNE SYSTEM | 02/01/21 | Crystal structure of SARS-CoV-2 RBD-targeting antibody COV107-23 HC + COVD21-C8 LC | HOMO SAPIENS | homo sapiens | homo sapiens | null | Yuan, M., Zhu, X., Wilson, I.A., Wu, N.C. | 3.4 | X-RAY DIFFRACTION | 0.312 | 0.276 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
1f3d | K | J | 0 | J | Hapten | TPM | 2-(4-AMINOBENZYLAMINO)-3,4,5,6-TETRAHYDROPYRIDINIUM | IMMUNE SYSTEM | 06/02/00 | CATALYTIC ANTIBODY 4B2 IN COMPLEX WITH ITS AMIDINIUM HAPTEN. | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Golinelli-Pimpaneau, B., Goncalves, O., Dintinger, T., Blanchard, D., Knossow, M., Tellier, C. | 1.87 | X-RAY DIFFRACTION | 0.218 | 0.198 | false | false | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
4m62 | I | M | 0 | T | protein | null | t117 | IMMUNE SYSTEM | 08/08/13 | Ontogeny of recognition specificity and functionality for the anti-HIV neutralizing antibody 4E10 | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | synthetic construct | Finton, K.A.K. | 1.8 | X-RAY DIFFRACTION | 0.216 | 0.189 | false | true | IGHV1 | IGKV3 | Kappa | 0 | -11.718948 | SPR | null | TBD |
4z5r | M | L | 0 | E | protein | null | interferon alpha-2 | Cytokine/Immune System | 04/02/15 | Rontalizumab Fab bound to Interferon-a2 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Eigenbrot, C., Maurer, B., Bosanac, I. | 3.0 | X-RAY DIFFRACTION | 0.251 | 0.223 | false | true | IGHV3 | IGKV1 | Kappa | 0 | -14.658431 | SPR | null | TBD |
3kdm | B | A | 0 | B | Hapten | TES | TESTOSTERONE | IMMUNE SYSTEM | 10/23/09 | Crystal Structure of Human Anti-steroid Fab 5F2 in Complex with Testosterone | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Niemi, M.H., Rouvinen, J. | 1.5 | X-RAY DIFFRACTION | 0.208 | 0.180 | true | true | IGHV3 | IGKV1 | Kappa | 0 | -9.54 | Other | 25 | 21360611 |
7zfe | H | L | 0 | E | protein | null | spike protein s1 | VIRAL PROTEIN | 04/01/22 | SARS-CoV-2 Omicron RBD in complex with Omi-32 Fab and nanobody C1 | LAMA GLAMA; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Zhou, D., Huo, J., Ren, J., Stuart, D.I. | 3.25 | X-RAY DIFFRACTION | 0.293 | 0.237 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
6do1 | D | null | 0 | B | protein | null | type-1 angiotensin ii receptor,soluble cytochrome b562 brilfusion protein | MEMBRANE PROTEIN | 06/08/18 | Structure of nanobody-stabilized angiotensin II type 1 receptor bound to S1I8 | HOMO SAPIENS; ESCHERICHIA COLI; SYNTHETIC CONSTRUCT | synthetic construct | null | homo sapiens, escherichia coli | Wingler, L.M., McMahon, C., Staus, D.P., Lefkowitz, R.J., Kruse, A.C. | 2.901 | X-RAY DIFFRACTION | 0.359 | 0.305 | false | true | IGHV1 | null | null | null | null | null | null | null |
7mxe | R | W | 0 | J | protein | null | envelope glycoprotein bg505 sosip.664 gp120 | ANTIVIRAL PROTEIN/VIRAL PROTEIN | 05/19/21 | Ab1245 Fab in complex with BG505 SOSIP.664 and 8ANC195 Fab | HOMO SAPIENS; HUMAN IMMUNODEFICIENCY VIRUS 1; MACACA MULATTA | macaca mulatta | macaca mulatta | human immunodeficiency virus 1 | Abernathy, M.E., Bjorkman, P.J. | 3.7 | ELECTRON MICROSCOPY | null | null | false | true | IGHV4 | IGLV9 | Lambda | null | null | null | null | null |
7nkt | B | null | 0 | A | protein | null | unknown | VIRAL PROTEIN | 02/18/21 | RBD domain of SARS-CoV2 in complex with neutralizing nanobody NM1226 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; VICUGNA PACOS | null | null | null | Ostertag, E., Zocher, G., Stehle, T. | 2.3 | X-RAY DIFFRACTION | 0.224 | 0.184 | false | false | IGHV1 | null | null | null | null | null | null | null |
7te9 | H | L | 0 | D | protein | null | glutamate receptor ionotropic, nmda 2b | SIGNALING PROTEIN/IMMUNE SYSTEM | 01/04/22 | Cryo-EM structure of GluN1b-2B NMDAR complexed to Fab2 class1 | RATTUS NORVEGICUS; MUS MUSCULUS | mus musculus | mus musculus | rattus norvegicus | Tajima, N., Furukawa, H. | 3.92 | ELECTRON MICROSCOPY | null | null | false | false | IGHV5 | IGKV19 | Kappa | null | null | null | null | null |
3hmw | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 05/29/09 | Crystal structure of ustekinumab FAB | HOMO SAPIENS | homo sapiens | homo sapiens | null | Luo, J. | 3.0 | X-RAY DIFFRACTION | 0.287 | 0.228 | false | true | IGHV5 | IGKV1D | Kappa | null | null | null | null | null |
5dk3 | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 09/02/15 | Crystal Structure of Pembrolizumab, a full length IgG4 antibody | HOMO SAPIENS | homo sapiens | homo sapiens | null | Scapin, G., Prosise, W., Reichert, P. | 2.28 | X-RAY DIFFRACTION | 0.224 | 0.184 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
7jr7 | C | D | 0 | B | A | protein | protein | NA | NA | atp-binding cassette sub-family g member 8 | atp-binding cassette sub-family g member 5 | TRANSLOCASE/IMMUNE SYSTEM | 08/11/20 | Cryo-EM structure of ABCG5/G8 in complex with Fab 2E10 and 11F4 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | homo sapiens | Huang, C.S., Yu, X., Min, X., Wang, Z., Zhang, H. | 3.3 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV4 | Kappa | null | null | null | null | null |
7n6p | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 06/08/21 | Crystal structure of the anti-EBOV and SUDV monoclonal antibody 1C3 Fab | HOMO SAPIENS | homo sapiens | homo sapiens | null | Milligan, J.C., Yu, X., Buck, T., Saphire, E.O. | 2.15 | X-RAY DIFFRACTION | 0.231 | 0.175 | false | true | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
5w9j | H | I | 0 | G | protein | null | spike glycoprotein | VIRAL PROTEIN | 06/23/17 | MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4 | MIDDLE EAST RESPIRATORY SYNDROME-RELATED CORONAVIRUS; MUS MUSCULUS | mus musculus | mus musculus | middle east respiratory syndrome-relatedcoronavirus | Pallesen, J., Ward, A.B. | 4.8 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
1bm3 | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 04/15/99 | IMMUNOGLOBULIN OPG2 FAB-PEPTIDE COMPLEX | MUS MUSCULUS | mus musculus | mus musculus | null | Kodandapani, R., Veerapandian, L., Ni, C.Z., Chiou, C.-K., Whital, R., Kunicki, T.J., Ely, K.R. | 2.0 | X-RAY DIFFRACTION | unknown | 0.152 | false | false | IGHV5 | IGKV5 | Kappa | null | null | null | null | null |
6e8v | U | V | 0 | null | null | null | null | IMMUNE SYSTEM | 09/04/19 | The crystal structure of bovine ultralong antibody BOV-1 | BOS TAURUS | bos taurus | bos taurus | null | Dong, J., Crowe, J.E. | 3.79 | X-RAY DIFFRACTION | 0.275 | 0.218 | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
7nka | F | null | 0 | null | null | null | null | VIRAL PROTEIN | 02/17/21 | 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8206 | INFLUENZA A VIRUS (A/BREVIG MISSION/1/1918(H1N1)); INFLUENZA A VIRUS (STRAIN A/BREVIG MISSION/1/1918 H1N1); CAMELIDAE MIXED LIBRARY; SYNTHETIC CONSTRUCT | camelidae mixed library | null | null | Keown, J.R., Carrique, L., Fodor, E., Grimes, J.M. | 4.07 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
5vxk | B | null | 0 | A | protein | null | invasin ipad | IMMUNE SYSTEM | 05/23/17 | 2.55 A resolution structure of IpaD from Shigella flexneri in complex with single-domain antibody JMK-H2 | VICUGNA PACOS; SHIGELLA FLEXNERI | vicugna pacos | null | shigella flexneri | Barta, M.L., Lovell, S., Battaile, K.P., Picking, W.D., Picking, W.L. | 2.55 | X-RAY DIFFRACTION | 0.273 | 0.202 | false | true | IGHV1 | null | null | null | null | null | null | null |
2qtj | B | M | 9 | null | null | null | null | IMMUNE SYSTEM | 08/02/07 | Solution structure of human dimeric immunoglobulin A | HOMO SAPIENS | homo sapiens | homo sapiens | null | Bonner, A., Furtado, P.B., Almogren, A., Kerr, M.A., Perkins, S.J. | NOT | SOLUTION SCATTERING | null | null | false | false | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
4xzu | A | B | 0 | M | protein | null | coagulation factor viii | IMMUNE SYSTEM | 02/05/15 | Crystal Structure of the Human Factor VIII C2 Domain in Complex with Murine 3E6 Inhibitory Antibody | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | Spiegel, P.C., Wuerth, M.E. | 2.61 | X-RAY DIFFRACTION | 0.267 | 0.199 | false | false | IGHV9 | IGKV4 | Kappa | null | null | null | null | null |
7m3i | A | B | 0 | C | protein | null | spike protein s1 | IMMUNE SYSTEM/VIRAL PROTEIN | 03/18/21 | Structure of SARS-CoV-2 spike protein receptor binding domain in complex with a neutralizing antibody, CV2-75 Fab | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Hurlburt, N.K., Pancera, M. | 2.8 | X-RAY DIFFRACTION | 0.281 | 0.245 | false | true | IGHV4 | IGLV3 | Lambda | null | null | null | null | null |
6ol7 | I | F | 0 | null | null | null | null | IMMUNE SYSTEM | 04/15/19 | Crystal structure of glVRC01 scFv in complex with anti-idiotype iv8 scFv | MUS MUSCULUS; HOMO SAPIENS | homo sapiens | homo sapiens | null | Weidle, C., Pancera, M. | 2.419 | X-RAY DIFFRACTION | 0.224 | 0.174 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
2or9 | H | L | 0 | P | peptide | null | synthetic epitope peptide of 9e10 | IMMUNE SYSTEM | 02/02/07 | The structure of the anti-c-myc antibody 9E10 Fab fragment/epitope peptide complex reveals a novel binding mode dominated by the heavy chain hypervariable loops | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | null | Krauss, N., Scheerer, P., Hoehne, W. | 2.7 | X-RAY DIFFRACTION | 0.310 | 0.252 | false | false | IGHV5 | IGKV3 | Kappa | 0.000001 | -8.6 | ITC | 25 | 18473392 |
5id1 | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 02/23/16 | Cetuximab Fab in complex with MPT-Cys meditope | MUS MUSCULUS, HOMO SAPIENS; SYNTHETIC CONSTRUCT | mus musculus, homo sapiens | mus musculus, homo sapiens | null | Bzymek, K.P., Williams, J.C. | 2.49 | X-RAY DIFFRACTION | 0.221 | 0.173 | false | true | IGHV2 | IGKV5 | Kappa | 0.000001 | -8.528998 | Unknown | null | TBD |
6oyh | H | null | 0 | D | protein | null | phospho-n-acetylmuramoyl-pentapeptide-transferase | MEMBRANE PROTEIN/TRANSFERASE | 05/14/19 | Crystal structure of MraY bound to carbacaprazamycin | LAMA GLAMA; AQUIFEX AEOLICUS (STRAIN VF5) | lama glama | null | aquifex aeolicus (strain vf5) | Mashalidis, E.H., Lee, S.Y. | 2.95 | X-RAY DIFFRACTION | 0.268 | 0.249 | false | true | IGHV1 | null | null | null | null | null | null | null |
1t66 | H | L | 0 | L | Hapten | FLU | 2-(6-HYDROXY-3-OXO-3H-XANTHEN-9-YL)-BENZOIC ACID | IMMUNE SYSTEM | 05/05/04 | The structure of FAB with intermediate affinity for fluorescein. | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Terzyan, S., Ramsland, P.A., Voss Jr., E.W., Herron, J.N., Edmundson, A.B. | 2.3 | X-RAY DIFFRACTION | 0.253 | 0.204 | false | false | IGHV6 | IGKV1 | Kappa | null | null | null | null | null |
7vuh | N | null | 0 | A | B | protein | protein | NA | NA | isoform gnas-2 of guanine nucleotide-binding protein g(s)subunit alpha isoforms short | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | MEMBRANE PROTEIN | 11/02/21 | Cryo-EM structure of a class A orphan GPCR | HOMO SAPIENS; BACILLUS CIRCULANS | homo sapiens | null | homo sapiens | homo sapiens | Liu, Z.J., Hua, T., Zhou, Y.L., Wu, L.J. | 3.22 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | null | null | null | null | null | null | null |
6mwn | C | D | 0 | B | nucleic-acid | null | hav dv rna (92-mer) | RNA/Immune System | 10/29/18 | Crystal structure of hepatitis A virus IRES domain V in complex with Fab HAVx | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | hepatovirus a | Koirala, D., Shao, Y., Piccirilli, J.A. | 2.838 | X-RAY DIFFRACTION | 0.252 | 0.186 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
3hzy | B | A | 0 | A | carbohydrate | KDA | polysaccharide | IMMUNE SYSTEM | 06/24/09 | Crystal structure of S73-2 antibody in complex with antigen Kdo(2.4)Kdo(2.4)Kdo | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Brooks, C.L., Muller-Loennies, S., Borisova, S.N., Brade, L., Kosma, P., Hirama, T., MacKenzie, C.R., Brade, H., Evans, S.V. | 2.1 | X-RAY DIFFRACTION | 0.261 | 0.216 | false | false | IGHV7 | IGKV8 | Kappa | 0 | -9.549709 | Unknown | null | TBD |
6hjy | F | null | 0 | A | protein | null | cys-loop ligand-gated ion channel | MEMBRANE PROTEIN | 09/04/18 | X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) Delta8 truncation mutant in complex with nanobody 72 | DICKEYA CHRYSANTHEMI; LAMA GLAMA | lama glama | null | dickeya chrysanthemi | Spurny, R., Govaerts, C., Evans, G.L., Pardon, E., Steyaert, J., Ulens, C. | 2.78 | X-RAY DIFFRACTION | 0.233 | 0.225 | false | true | IGHV1 | null | null | null | null | null | null | null |
4yny | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 03/11/15 | Crystal structure of monoclonal anti-human podoplanin antibody NZ-1 | RATTUS NORVEGICUS | rattus norvegicus | rattus norvegicus | null | Fujii, Y., Kitago, Y., Arimori, T., Takagi, J. | 1.584 | X-RAY DIFFRACTION | 0.204 | 0.168 | false | true | IGHV5 | IGLV3 | Lambda | null | null | null | null | null |
4wht | U | V | 0 | u | peptide | null | unknown | VIRAL PROTEIN | 09/23/14 | Structure of the Hepatitis C virus envelope glycoprotein E2 antigenic region 412-423 bound to the broadly neutralizing antibody 3/11, P1 crystal form | HEPATITIS C VIRUS; RATTUS NORVEGICUS | rattus norvegicus | rattus norvegicus | hepatitis c virus | Krey, T., Rey, F.A. | 2.22 | X-RAY DIFFRACTION | 0.243 | 0.209 | false | true | IGHV5 | IGKV2 | Kappa | 0 | -11.053614 | Unknown | null | TBD |
4w2q | C | null | 0 | D | protein | null | nucleoprotein | IMMUNE SYSTEM | 08/17/17 | Anti-Marburgvirus Nucleoprotein Single Domain Antibody C Complexed with Nucleoprotein C-terminal domain | LAMA GLAMA; LAKE VICTORIA MARBURGVIRUS | lama glama | null | lake victoria marburgvirus | Taylor, A.B., Garza, J.A. | 2.7 | X-RAY DIFFRACTION | 0.274 | 0.220 | false | true | IGHV1 | null | null | null | null | null | null | null |
3lh2 | I | M | 0 | T | protein | null | 4e10_1vi7a_s0_002_n (t88) | IMMUNE SYSTEM | 01/21/10 | Crystal structure of HIV epitope-scaffold 4E10_1VI7A_S0_002_N 4E10 Fv complex | ARTIFICIAL GENE; HOMO SAPIENS | homo sapiens | homo sapiens | artificial gene | Holmes, M.A. | 2.65 | X-RAY DIFFRACTION | 0.270 | 0.222 | false | true | IGHV1 | IGKV3 | Kappa | 0 | -11.25 | SPR | null | 20826338 |
7lly | N | null | 0 | A | B | protein | protein | NA | NA | guanine nucleotide-binding protein g(s) subunit alphaisoforms short | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | MEMBRANE PROTEIN | 02/04/21 | Oxyntomodulin-bound Glucagon-Like Peptide-1 (GLP-1) Receptor in complex with Gs protein | HOMO SAPIENS; LAMA GLAMA; SUS SCROFA | lama glama | null | homo sapiens | homo sapiens | Wootten, D., Sexton, P.M., Belousoff, M.J., Danev, R., Zhang, X., Khoshouei, M., Venugopal, H. | 3.3 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | null | null | null | null | null | null | null |
7qjj | F | null | 0 | E | protein | null | divalent metal cation transporter | MEMBRANE PROTEIN | 12/16/21 | X-Ray Structure of a Mn2+ soak of EleNRMT in complex with two Nanobodies at 4.6A | EGGERTHELLA LENTA | eggerthella lenta | null | eggerthella lenta | Ramanadane, K., Straub, M.S., Dutzler, R., Manatschal, C. | 4.6 | X-RAY DIFFRACTION | 0.327 | 0.284 | false | true | IGHV1 | null | null | null | null | null | null | null |
6zqk | B | null | 0 | null | null | null | null | ANTITUMOR PROTEIN | 07/09/20 | HER2-binding scFv-Fab fusion 841 | MUS MUSCULUS | mus musculus | null | null | Kast, F., Schwill, M., Stueber, J.C., Pfundstein, S., Nagy-Davidescu, G., Monne Rodriguez, J.M., Seehusen, F., Richter, C.P., Honegger, A., Hartmann, K.P., Weber, T.G., Kroener, F., Ernst, P., Piehler, J., Plueckthun, A. | 2.2 | X-RAY DIFFRACTION | 0.241 | 0.202 | false | true | IGHV1 | null | null | null | null | null | null | null |
4n8c | I | M | 0 | Y | peptide | null | extracellular domain of influenza matrix protein 2 | IMMUNE SYSTEM | 10/17/13 | Three-dimensional structure of the extracellular domain of Matrix protein 2 of influenza A virus | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | influenza a virus (a/puerto rico/8/1934(h1n1)) | Cho, K.J., Seok, J.H., Kim, S., Roose, K., Schepens, B., Fiers, W., Saelens, X., Kim, K.H. | 1.6 | X-RAY DIFFRACTION | 0.242 | 0.193 | false | false | IGHV1 | IGKV8 | Kappa | 0 | -12.821084 | Unknown | null | TBD |
7pi3 | Y | Z | 0 | V | protein | null | cysteine-rich protective antigen | IMMUNE SYSTEM | 08/19/21 | PfCyRPA bound to Fab fragments from monoclonal antibodies Cy.003, Cy.004 and Cy.007 | PLASMODIUM FALCIPARUM 3D7; GALLUS GALLUS | gallus gallus | gallus gallus | plasmodium falciparum 3d7 | Ragotte, R.J., Higgins, M.K. | 3.269 | X-RAY DIFFRACTION | 0.298 | 0.285 | false | true | unknown | unknown | unknown | null | null | null | null | null |
7mzm | H | L | 0 | A | protein | null | spike protein s1 | VIRAL PROTEIN | 05/24/21 | SARS-CoV-2 receptor binding domain bound to Fab PDI 215 | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Pymm, P., Dietrich, M.H., Tan, L.L., Chan, L.J., Tham, W.H. | 2.3 | X-RAY DIFFRACTION | 0.257 | 0.216 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
6mtq | H | L | 0 | T | protein | null | vrc42 epitope t117-f scaffold | IMMUNE SYSTEM | 10/21/18 | Crystal structure of VRC42.N1 Fab in complex with T117-F MPER scaffold | HOMO SAPIENS; HUMAN IMMUNODEFICIENCY VIRUS 1 | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Kwon, Y.D., Law, W.H., Veradi, R., Doria-Rose, N.A., Kwong, P.D. | 2.7 | X-RAY DIFFRACTION | 0.259 | 0.206 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
1a4j | B | A | 0 | null | null | null | null | IMMUNOGLOBULIN | 01/30/98 | DIELS ALDER CATALYTIC ANTIBODY GERMLINE PRECURSOR | MUS MUSCULUS | mus musculus | mus musculus | null | Spiller, B.W., Romesburg, F.E., Schultz, P.G., Stevens, R.C. | 2.1 | X-RAY DIFFRACTION | 0.292 | 0.229 | false | true | IGHV9 | IGKV1 | Kappa | null | null | null | null | null |
4n90 | H | I | 0 | T | C | protein | protein | NA | NA | tumor necrosis factor receptor superfamily member 10b | tumor necrosis factor ligand superfamily member 10 | Apoptosis/Immune System | 10/18/13 | Crystal structure of ternary complex of TRAIL, DR5, and Fab fragment from a DR5 agonist antibody | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | homo sapiens | Huang, X. | 3.3 | X-RAY DIFFRACTION | 0.286 | 0.229 | false | true | IGHV4 | IGKV3 | Kappa | null | null | null | null | null |
6xy2 | H | L | 0 | A | protein | null | cytotoxic t-lymphocyte protein 4 | IMMUNE SYSTEM | 01/29/20 | Crystal structure of CTLA-4 complexed with the Fab of HL32 antibody | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Gao, H., Zhou, A. | 3.05 | X-RAY DIFFRACTION | 0.293 | 0.249 | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
6dzm | G | H | 0 | D | A | protein | protein | NA | NA | bundibugyo virus gp2 | bundibugyo virus gp1 | VIRAL PROTEIN | 07/05/18 | Bundibugyo virus GP (mucin-deleted) in complex with pan-ebolavirus human antibody ADI-15878 Fab | BUNDIBUGYO EBOLAVIRUS; HOMO SAPIENS | homo sapiens | homo sapiens | bundibugyo ebolavirus | bundibugyo ebolavirus | Murin, C.D., Ward, A.B. | 4.29 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
2b4c | H | L | 0 | G | C | protein | protein | NA | NA | envelope glycoprotein | t-cell surface glycoprotein cd4 | Viral protein/Immune system | 09/23/05 | Crystal structure of HIV-1 JR-FL gp120 core protein containing the third variable region (V3) complexed with CD4 and the X5 antibody | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | human immunodeficiency virus 1 | homo sapiens | Huang, C., Tang, M., Zhang, M.Y., Majeed, S., Montabana, E., Stanfield, R.L., Dimitrov, D.S., Korber, B., Sodroski, J., Wilson, I.A., Wyatt, R., Kwong, P.D. | 3.3 | X-RAY DIFFRACTION | 0.349 | 0.319 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
4r97 | C | B | 0 | null | null | null | null | IMMUNE SYSTEM | 09/03/14 | Crystal structure of the Fab fragment of KKO | MUS MUSCULUS | mus musculus | mus musculus | null | Cai, Z., Zhu, Z., Liu, Q., Greene, M.I. | 2.2 | X-RAY DIFFRACTION | 0.262 | 0.200 | false | true | IGHV1 | IGKV6 | Kappa | null | null | null | null | null |
7b2m | D | null | 0 | B | A | protein | protein | NA | NA | complement c4 alpha chain | complement c4 beta chain | IMMUNE SYSTEM | 11/27/20 | Cryo-EM structure of complement C4b in complex with nanobody E3 | LAMA GLAMA; HOMO SAPIENS | lama glama | null | homo sapiens | homo sapiens | Oosterheert, W., De la O Becerra, K.I., van den Bos, R.M., Gros, P. | 3.39 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
5mp1 | H | L | 0 | A | peptide | null | microtubule-associated protein tau | IMMUNE SYSTEM | 12/15/16 | Crystal structure of DC8E8 Fab in the complex with a 14-mer tau peptide at pH 7.5 | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | homo sapiens | Skrabana, R., Novak, M., Cehlar, O., Kontsekova, E. | 3.1 | X-RAY DIFFRACTION | 0.268 | 0.222 | false | false | IGHV1 | IGKV8 | Kappa | null | null | null | null | null |
6j7w | A | null | 0 | C | peptide | null | tumor necrosis factor receptor superfamily member 17 | IMMUNE SYSTEM | 01/18/19 | Crystal Structure of Human BCMA in complex with UniAb(TM) VH | HOMO SAPIENS | homo sapiens | null | homo sapiens | Clarke, S.C., Ma, B., Trinklein, N.D., Schellenberger, U., Osborn, M., Ouisse, L., Boudreau, A., Davison, L., Harris, K.E., Ugamraj, H., Balasubramani, A., Dang, K., Jorgensen, B., Ogana, H., Pham, D., Pratap, P., Sankaran, P., Anegon, I., van Schooten, W., Bruggemann, M., Buelow, R., Force Aldred, S. | 2.6 | X-RAY DIFFRACTION | 0.271 | 0.209 | false | true | IGHV3 | null | null | null | null | null | null | null |
7sob | M | L | 0 | K | protein | null | spike glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 10/29/21 | SARS-CoV-2 S B.1.617.1 kappa variant + S309 + S2L20 Global Refinement | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | McCallum, M., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 2.4 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
5fyl | H | L | 0 | G | protein | null | bg505 gp120 env ectodomain | null | 03/08/16 | Crystal Structure at 3.7 A Resolution of Fully Glycosylated HIV-1 Clade A BG505 SOSIP.664 Prefusion Env Trimer in Complex with Broadly Neutralizing Antibodies PGT122 and 35O22 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Stewart-Jones, G.B.E., Zhou, T., Kwong, P.D. | 3.1 | X-RAY DIFFRACTION | 0.3072 | 0.2503 | false | true | IGHV4 | IGLV3 | Lambda | null | null | null | null | null |
7ws2 | E | D | 0 | A | protein | null | spike protein s1 | VIRAL PROTEIN/IMMUNE SYSTEM | 01/28/22 | Structures of Omicron Spike complexes illuminate broad-spectrum neutralizing antibody development | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Guo, H., Gao, Y., Ji, X., Yang, H. | 3.3 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6anp | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 08/14/17 | CAT192 Fab Insertion Mutant H5/L0 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Lord, D.M., Wei, R.R. | 2.45 | X-RAY DIFFRACTION | 0.235 | 0.183 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
5xct | A | B | 0 | C | peptide | null | c8 peptide | IMMUNE SYSTEM | 03/23/17 | Crystal structure of P20.1 Fv-clasp fragment with its antigen peptide | MUS MUSCULUS; HOMO SAPIENS; SYNTHETIC CONSTRUCT | mus musculus, homo sapiens | mus musculus, homo sapiens | homo sapiens | Arimori, T., Takagi, J. | 1.17 | X-RAY DIFFRACTION | 0.185 | 0.152 | false | true | IGHV9 | IGLV1 | Lambda | null | null | null | null | null |
6co3 | H | L | 0 | Q | peptide | null | ala-glu-phe-arg-his-asp | IMMUNE SYSTEM | 03/10/18 | aducanumab abeta complex | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Arndt, J.W. | 2.384 | X-RAY DIFFRACTION | 0.235 | 0.181 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
3bkj | H | L | 0 | A | peptide | null | amyloid beta peptide | IMMUNE SYSTEM | 12/06/07 | Crystal structure of Fab wo2 bound to the n terminal domain of amyloid beta peptide (1-16) | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | null | Miles, L.A., Wun, K.S., Crespi, G.A., Fodero-Tavoletti, M., Galatis, D., Bageley, C.J., Beyreuther, K., Masters, C.L., Cappai, R., McKinstry, W.J., Barnham, K.J., Parker, M.W. | 1.59 | X-RAY DIFFRACTION | 0.231 | 0.188 | false | false | IGHV8 | IGKV1 | Kappa | null | null | null | null | null |
2z91 | C | D | 0 | null | null | null | null | IMMUNE SYSTEM | 09/14/07 | Crystal structure of the Fab fragment of anti-ciguatoxin antibody 10C9 | MUS MUSCULUS | mus musculus | mus musculus | null | Ui, M., Tanaka, Y., Tsumoto, K. | 2.6 | X-RAY DIFFRACTION | 0.270 | 0.220 | false | true | IGHV3 | IGKV4 | Kappa | null | null | null | null | null |
6okn | A | B | 0 | R | protein | null | tumor necrosis factor receptor superfamily member 4 | IMMUNE SYSTEM | 04/14/19 | OX40R (TNFRSF4) bound to Fab 1A7 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Ultsch, M.H., Boenig, G., Harris, S.F. | 3.25 | X-RAY DIFFRACTION | 0.228 | 0.192 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
5foj | A | null | 0 | B | protein | null | grapevine fanleaf virus | null | 11/22/15 | Electron cryo-microscopy of Grapevine Fanleaf Virus complex with Nanobody | GRAPEVINE FANLEAF VIRUS | grapevine fanleaf virus | null | grapevine fanleaf virus | Hemmer, C., Orlov, I., Ackerer, L., Marmonier, A., Hleibieh, K., Schmitt-Keichinger, C., Vigne, E., Gersch, S., Komar, V., Belval, L., Berthold, F., Monsion, B., Bron, P., Lemaire, O., Lorber, B., Sgro, J.Y., Gutierrez, C., Muyldermans, S., Demangeat, G., Klaholz, B.P., Ritzenthaler, C. | 2.8 | ELECTRON MICROSCOPY | null | null | false | false | IGHV1 | null | null | null | null | null | null | null |
6xun | H | L | 0 | E | carbohydrate | NAG | N-ACETYL-D-GLUCOSAMINE | ANTITUMOR PROTEIN | 01/20/20 | Ab 5b1 bound to CA19-9 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Diskin, R., Borenstein-Katz, A. | 2.41 | X-RAY DIFFRACTION | 0.215 | 0.169 | false | true | IGHV3 | IGLV1 | Lambda | null | null | null | null | null |
3cm9 | D | O | 6 | null | null | null | null | IMMUNE SYSTEM | 03/21/08 | Solution Structure of Human SIgA2 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Bonner, A., Almogren, A., Furtado, P.B., Kerr, M.A., Perkins, S.J. | NOT | SOLUTION SCATTERING | null | null | false | false | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
2kh2 | B | b | 4 | A | protein | null | interleukin-1 beta | Cytokine/IMMUNE SYSTEM | 03/23/09 | Solution structure of a scFv-IL-1B complex | HOMO SAPIENS; MUS MUSCULUS | mus musculus | null | homo sapiens | Wilkinson, I.C., Hall, C.J., Veverka, V., Muskett, F.W., Stephens, P.E., Taylor, R.J., Henry, A.J., Carr, M.D. | NOT | SOLUTION NMR | null | null | true | true | unknown | unknown | unknown | null | null | null | null | null |
3j2y | D | C | 0 | null | null | null | null | IMMUNE SYSTEM | 01/28/13 | Electron Cryo-microscopy of Chikungunya VLP in complex with neutralizing antibody Fab 9.8B | MUS MUSCULUS | mus musculus | mus musculus | null | Sun, S., Xiang, Y., Rossmann, M.G. | 14.9 | ELECTRON MICROSCOPY | null | null | false | false | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
7rth | D | C | 0 | null | null | null | null | IMMUNE SYSTEM | 08/13/21 | Crystal structure of an anti-lysozyme nanobody in complex with an anti-nanobody Fab ""NabFab"" | HOMO SAPIENS | homo sapiens | homo sapiens | null | Filippova, E.V., Mukherjee, S., Bloch, J.S., Locher, K.P., Kossiakoff, A.A. | 3.19 | X-RAY DIFFRACTION | 0.267 | 0.216 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
3bd4 | null | A | 0 | null | null | null | null | IMMUNE SYSTEM | 11/14/07 | Crystal structure of single domain VL of an anti-DNA binding antibody 3D8 scFv and its active site revealed by complex structures of a small molecule and metals | MUS MUSCULUS | null | mus musculus | null | Park, S.K., Kim, J.S. | 2.4 | X-RAY DIFFRACTION | 0.281 | 0.213 | true | true | null | IGKV8 | Kappa | null | null | null | null | null |
6p8n | H | L | 0 | C | protein | null | env outer domain eod-gt8 | IMMUNE SYSTEM | 06/07/19 | Crystal Structure of Antibody P-p1f1 in Complex with eOD-GT8 | HUMAN IMMUNODEFICIENCY VIRUS 1; MUS MUSCULUS | mus musculus | mus musculus | human immunodeficiency virus 1 | Weidle, C., Pancera, M. | 3.202 | X-RAY DIFFRACTION | 0.287 | 0.226 | false | true | IGHV1 | IGKV8 | Kappa | null | null | null | null | null |
7ryv | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 08/26/21 | Anti-HIV neutralizing antibody Ab1573 Fab isolated from sequentially immunized macaques | MACACA MULATTA | macaca mulatta | macaca mulatta | null | Yang, Z., Bjorkman, P.J. | 2.5 | X-RAY DIFFRACTION | 0.254 | 0.216 | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
7kxj | I | M | 0 | B | protein | null | spike glycoprotein | VIRAL PROTEIN/Immune System | 12/04/20 | SARS-CoV-2 spike protein in complex with Fab 15033-7, 3-""up"", asymmetric | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Li, Z., Rini, J. | 6.4 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
3r08 | H | L | 0 | E | protein | null | t-cell surface glycoprotein cd3 epsilon chain | IMMUNE SYSTEM | 03/07/11 | Crystal structure of mouse cd3epsilon in complex with antibody 2C11 Fab | CRICETULUS MIGRATORIUS | cricetulus migratorius | cricetulus migratorius | cricetulus migratorius | Shore, D.A., Zhu, X., Wilson, I.A. | 4.1 | X-RAY DIFFRACTION | 0.277 | 0.222 | false | true | IGHV5 | IGKV14 | Kappa | null | null | null | null | null |
7mlz | H | L | 0 | A | protein | null | spike protein s1 | IMMUNE SYSTEM/VIRAL PROTEIN | 04/29/21 | Cryo-EM structure of SARS-CoV-2 spike in complex with neutralizing antibody B1-182.1 that targets the receptor-binding domain | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Zhou, T., Tsybovsky, T., Kwong, P.D. | 3.71 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
3zkq | D | null | 0 | A | protein | null | beta-secretase 2 | HYDROLASE/IMMUNE SYSTEM | 01/24/13 | BACE2 XAPERONE COMPLEX | LAMA GLAMA; HOMO SAPIENS | lama glama | null | homo sapiens | Banner, D.W., Kuglstatter, A., Benz, J., Stihle, M., Ruf, A. | 1.51 | X-RAY DIFFRACTION | 0.22276 | 0.18966 | false | true | IGHV3 | null | null | 0 | -12.170174 | SPR | null | TBD |
4hwb | H | L | 0 | A | protein | null | interleukin-13 receptor subunit alpha-1 | IMMUNE SYSTEM | 11/07/12 | Crystal structure of ectodomain 3 of the IL-13 receptor alpha 1 in complex with a human neutralizing monoclonal antibody fragment | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Xu, Y. | 2.61 | X-RAY DIFFRACTION | 0.224 | 0.197 | false | true | IGHV5 | IGKV3 | Kappa | 0 | -12.611243 | Unknown | null | TBD |
7ljb | G | F | 0 | B | protein | null | isoform 2 of potassium channel subfamily k member 4 | METAL TRANSPORT/Immune System | 01/28/21 | Human TRAAK K+ channel mutant G158D in a K+ bound conductive conformation | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | Rietmeijer, R.A., Brohawn, S.G. | 2.97 | X-RAY DIFFRACTION | 0.240 | 0.196 | false | true | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
3p9w | D | null | 0 | C | protein | null | vascular endothelial growth factor a | SIGNALING PROTEIN/IMMUNE SYSTEM | 10/18/10 | Crystal structure of an engineered human autonomous VH Domain in complex with VEGF | HOMO SAPIENS | homo sapiens | null | homo sapiens | Ma, X., Wiesmann, C. | 2.41 | X-RAY DIFFRACTION | 0.233 | 0.193 | false | true | IGHV3 | null | null | 0 | -10.635483 | SPR | null | TBD |
5w9o | B | C | 0 | A | protein | null | spike glycoprotein | VIRAL PROTEIN | 06/23/17 | MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4 | MIDDLE EAST RESPIRATORY SYNDROME-RELATED CORONAVIRUS; MUS MUSCULUS | mus musculus | mus musculus | middle east respiratory syndrome-relatedcoronavirus | Pallesen, J., Ward, A.B. | 4.5 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
7tes | H | L | 0 | B | A | protein | protein | NA | NA | glutamate receptor ionotropic, nmda 2b | glutamate receptor ionotropic, nmda 1 | SIGNALING PROTEIN/IMMUNE SYSTEM | 01/05/22 | Cryo-EM structure of GluN1b-2B NMDAR in complex with Fab5 in Non-active1 conformation | RATTUS NORVEGICUS; MUS MUSCULUS | mus musculus | mus musculus | rattus norvegicus | rattus norvegicus | Tajima, N., Furukawa, H. | 4.7 | ELECTRON MICROSCOPY | null | null | false | false | IGHV5 | IGKV3 | Kappa | null | null | null | null | null |
5nbl | F | null | 0 | D | A | protein | protein | NA | NA | actin | actin-related protein 4 | HYDROLASE | 03/02/17 | Crystal structure of the Arp4-N-actin(APO-state) heterodimer bound by a nanobody | SACCHAROMYCES CEREVISIAE (STRAIN ATCC 204508 / S288C); VICUGNA PACOS; TRICHOPLUSIA NI | vicugna pacos | null | saccharomyces cerevisiae (strain atcc 204508 /s288c) | saccharomyces cerevisiae (strain atcc 204508 /s288c) | Knoll, K.R., Eustermann, S., Hopfner, K.P. | 2.8 | X-RAY DIFFRACTION | 0.204 | 0.171 | false | true | IGHV1 | null | null | null | null | null | null | null |
7b0b | H | L | 0 | F | protein | null | surface glycoprotein | ANTIVIRAL PROTEIN | 11/19/20 | Fab HbnC3t1p1_C6 bound to SARS-CoV-2 RBD | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Borenstein-Katz, A., Diskin, R. | 2.98 | X-RAY DIFFRACTION | 0.246 | 0.209 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
6xsw | H | L | 0 | X | protein | null | neurogenic locus notch homolog protein 3 | SIGNALING PROTEIN/Immune System | 07/16/20 | Structure of the Notch3 NRR in complex with an antibody Fab Fragment | RATTUS NORVEGICUS; HOMO SAPIENS | rattus norvegicus | rattus norvegicus | homo sapiens | Bard, J. | 2.98 | X-RAY DIFFRACTION | 0.256 | 0.233 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
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