pdb stringlengths 4 4 | Hchain stringclasses 59
values | Lchain stringclasses 60
values | model int64 0 76 | antigen_chain stringclasses 386
values | antigen_type stringclasses 24
values | antigen_het_name stringclasses 240
values | antigen_name stringlengths 1 396 ⌀ | short_header stringclasses 448
values | date stringlengths 8 8 | compound stringlengths 4 243 | organism stringlengths 3 175 ⌀ | heavy_species stringclasses 121
values | light_species stringclasses 67
values | antigen_species stringclasses 937
values | authors stringlengths 6 762 | resolution stringlengths 1 8 | method stringclasses 10
values | r_free stringclasses 354
values | r_factor stringclasses 342
values | scfv bool 2
classes | engineered bool 2
classes | heavy_subclass stringclasses 14
values | light_subclass stringclasses 35
values | light_ctype stringclasses 3
values | affinity float64 0 0 ⌀ | delta_g float64 -16.91 -5.04 ⌀ | affinity_method stringclasses 11
values | temperature float64 4 37 ⌀ | pmid stringclasses 157
values |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
7tn0 | B | A | 0 | I | protein | null | spike protein s1 | VIRAL PROTEIN/IMMUNE SYSTEM | 01/20/22 | SARS-CoV-2 Omicron RBD in complex with human ACE2 and S304 Fab and S309 Fab | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Snell, G., McCallum, M., Veesler, D., Nix, J.C., Croll, T.I., Dillen, J.R., Czudnochowski, N. | 2.85 | X-RAY DIFFRACTION | 0.268 | 0.230 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
3bqu | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 12/20/07 | Crystal Structure of the 2F5 Fab'-3H6 Fab Complex | HOMO SAPIENS; MUS MUSCULUS | homo sapiens | homo sapiens | null | Bryson, S., Julien, J.-P., Isenman, D.E., Kunert, R., Katinger, H., Pai, E.F. | 3.0 | X-RAY DIFFRACTION | 0.295 | 0.276 | false | false | IGHV2 | IGKV1D | Kappa | null | null | null | null | null |
5a8h | J | I | 0 | G | protein | null | hiv-1 gp120 | VIRAL PROTEIN/IMMUNE SYSTEM | 07/15/15 | cryo-ET subtomogram averaging of BG505 SOSIP.664 in complex with sCD4, 17b, and 8ANC195 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Scharf, L., Wang, H., Gao, H., Chen, S., McDowall, A., Bjorkman, P. | 23.0 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
6udj | D | E | 0 | P | protein | null | envelope glycoprotein gp120 | VIRAL PROTEIN/IMMUNE SYSTEM | 09/19/19 | HIV-1 bNAb 1-18 in complex with BG505 SOSIP.664 and 10-1074 | HOMO SAPIENS; HUMAN IMMUNODEFICIENCY VIRUS 1 | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Abernathy, M.E., Barnes, C.O., Gristick, H.B., Bjorkman, P.J. | 2.5 | ELECTRON MICROSCOPY | null | null | false | true | unknown | IGKV3 | Kappa | null | null | null | null | null |
1mak | null | A | 12 | null | null | null | null | IMMUNOGLOBULIN | 09/16/93 | SOLUTION STRUCTURE OF AN ISOLATED ANTIBODY VL DOMAIN | MUS MUSCULUS | null | mus musculus | null | Constantine, K.L., Friedrichs, M.S., Metzler, W.J., Wittekind, M., Hensley, P., Mueller, L. | NOT | SOLUTION NMR | null | null | false | true | unknown | unknown | unknown | null | null | null | null | null |
7wlc | H | L | 0 | E | protein | null | spike protein s1 | VIRAL PROTEIN/IMMUNE SYSTEM | 01/13/22 | SARS-CoV-2 Omicron variant spike protein in complex with Fab XGv265 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Wang, X., Wang, L. | 4 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
5itb | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 03/16/16 | Crystal structure of the anti-RSV F Fab 14N4 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Mousa, J.J., Crowe, J.E. | 2.0 | X-RAY DIFFRACTION | 0.214 | 0.194 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6x3u | J | I | 0 | B | protein | null | gamma-aminobutyric acid receptor subunit alpha-1 | TRANSPORT PROTEIN | 05/21/20 | Human GABAA receptor alpha1-beta2-gamma2 subtype in complex with GABA plus flumazenil | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | Kim, J.J., Gharpure, A., Teng, J., Zhuang, Y., Howard, R.J., Zhu, S., Noviello, C.M., Walsh, R.M., Lindahl, E., Hibbs, R.E. | 3.49 | ELECTRON MICROSCOPY | null | null | false | false | IGHV14 | IGKV6 | Kappa | null | null | null | null | null |
4g80 | C | D | 0 | J | protein | null | voltage-sensor containing phosphatase | membrane protein | 07/20/12 | Crystal structure of voltage sensing domain of Ci-VSP with fragment antibody (WT, 3.8 A) | HOMO SAPIENS; CIONA INTESTINALIS | homo sapiens | homo sapiens | ciona intestinalis | Li, Q. | 3.58 | X-RAY DIFFRACTION | 0.292 | 0.248 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
7ld1 | H | L | 0 | B | protein | null | spike glycoprotein | IMMUNE SYSTEM | 01/12/21 | Structure of SARS-CoV-2 S protein in complex with Receptor Binding Domain antibody DH1047 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Manne, K., Acharya, P. | 3.4 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
6vzi | H | L | 0 | G | protein | null | envelope glycoprotein gp160 | VIRAL PROTEIN/IMMUNE SYSTEM | 02/28/20 | Crystal Structure of HIV-1 CAP256 RnS-3mut-2G-SOSIP.664 Prefusion Env Trimer in Complex with Human Antibodies 3H109L and 35O22 at 3.5 Angstrom | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Lai, Y.-T., Kwong, P.D. | 2.716 | X-RAY DIFFRACTION | 0.276 | 0.229 | false | true | IGHV4 | unknown | unknown | null | null | null | null | null |
2e27 | H | L | 0 | H | Hapten | AB0 | 3,7:6,10:9,14-TRIANHYDRO-2,5,11,12,13-PENTADEOXY-4-O-(METHOXYMETHYL)-L-ARABINO-L-ALLO-TETRADEC-12-ENONIC ACID | IMMUNE SYSTEM | 11/08/06 | Crystal structure of Fv fragment of anti-ciguatoxin antibody complexed with ABC-ring of ciguatoxin | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Yokota, A., Tanaka, Y., Tsumoto, K. | 1.7 | X-RAY DIFFRACTION | 0.210 | 0.198 | false | true | IGHV1 | IGKV19 | Kappa | 0 | -12.7513 | Unknown | null | TBD |
1c5b | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 11/08/99 | DECARBOXYLASE CATALYTIC ANTIBODY 21D8 UNLIGANDED FORM | MUS MUSCULUS, HOMO SAPIENS | mus musculus, homo sapiens | mus musculus, homo sapiens | null | Hotta, K., Wilson, I.A. | 2.1 | X-RAY DIFFRACTION | 0.238 | 0.188 | false | true | IGHV1 | IGKV9 | Kappa | null | null | null | null | null |
3uc0 | H | L | 0 | A | protein | null | envelope protein | VIRAL PROTEIN/IMMUNE SYSTEM | 10/25/11 | Crystal structure of domain I of the envelope glycoprotein ectodomain from dengue virus serotype 4 in complex with the fab fragment of the chimpanzee monoclonal antibody 5H2 | DENGUE VIRUS 4; PAN TROGLODYTES | pan troglodytes | pan troglodytes | dengue virus 4 | Cockburn, J.J.B., Stura, E.A., Navarro-Sanchez, M.E., Rey, F.A. | 2.71 | X-RAY DIFFRACTION | 0.252 | 0.220 | false | true | IGHV4 | IGKV1 | Kappa | 0 | -12.6 | Other | 37 | 22139356 |
7ksg | F | null | 0 | C | protein | null | spike glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 11/22/20 | SARS-CoV-2 spike in complex with nanobodies E | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; CAMELUS BACTRIANUS | camelus bactrianus | null | severe acute respiratory syndrome coronavirus2 | Hallberg, B.M., Das, H. | 3.33 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
6qn8 | G | I | 0 | null | null | null | null | IMMUNE SYSTEM | 02/10/19 | Structure of bovine anti-RSV Fab B13 | BOS TAURUS | bos taurus | bos taurus | null | Ren, J., Nettleship, J.E., Harris, G., Mwangi, W., Rhaman, N., Grant, C., Kotecha, A., Fry, E., Charleston, B., Stuart, D.I., Hammond, J., Owens, R.J. | 2.12 | X-RAY DIFFRACTION | 0.267 | 0.235 | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
2rhe | null | A | 0 | null | null | null | null | IMMUNOGLOBULIN | 06/13/83 | STRUCTURE OF A NOVEL BENCE-JONES PROTEIN (RHE) FRAGMENT AT 1.6 ANGSTROMS RESOLUTION | HOMO SAPIENS | null | homo sapiens | null | Fureyjunior, W., Wang, B.C., Yoo, C.S., Sax, M. | 1.6 | X-RAY DIFFRACTION | unknown | 0.149 | false | true | unknown | unknown | unknown | null | null | null | null | null |
7shu | C | D | 0 | A | protein | null | immunoglobulin heavy constant epsilon | IMMUNE SYSTEM | 10/11/21 | IgE-Fc in complex with omalizumab variant C02 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Pennington, L.F., Jardetzky, T.J., Kleinboelting, S. | 2.75 | X-RAY DIFFRACTION | 0.275 | 0.220 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
4y5x | D | E | 0 | F | protein | null | erythropoietin receptor | protein binding/immune system | 02/12/15 | Diabody 305 complex with EpoR | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Moraga, I., Guo, F., Ozkan, E., Jude, K.M., Garcia, K.C. | 3.15 | X-RAY DIFFRACTION | 0.241 | 0.201 | false | true | IGHV3 | IGLV1 | Lambda | null | null | null | null | null |
2adg | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 07/20/05 | Crystal structure of monoclonal anti-CD4 antibody Q425 | MUS MUSCULUS | mus musculus | mus musculus | null | Zhou, T., Hamer, D.H., Hendrickson, W.A., Sattentau, Q.J., Kwong, P.D. | 2.5 | X-RAY DIFFRACTION | 0.244 | 0.203 | false | false | IGHV5 | IGKV17 | Kappa | null | null | null | null | null |
2otu | H | G | 0 | S | peptide | null | peptide antigen | IMMUNE SYSTEM | 02/09/07 | Crystal structure of Fv polyglutamine complex | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | null | Li, P. | 1.68 | X-RAY DIFFRACTION | 0.214 | 0.200 | false | true | IGHV5 | IGLV3 | Lambda | null | null | null | null | null |
2x1o | A | null | 0 | null | null | null | null | CONTRACTILE PROTEIN | 01/03/10 | Gelsolin Nanobody | LAMA GLAMA | lama glama | null | null | Van den Abbeele, A., DeClercq, S., DeGanck, A., DeCorte, V., Van Loo, B., Srinivasan, V., Steyaert, J., Vandekerckhove, J., Gettemans, J. | 1.34 | X-RAY DIFFRACTION | 0.24007 | 0.21135 | false | true | IGHV1 | null | null | null | null | null | null | null |
6b0e | B | A | 0 | E | protein | null | 25 kda ookinete surface antigen | IMMUNE SYSTEM | 09/14/17 | Crystal structure of Pfs25 in complex with the transmission blocking antibody 1260 | HOMO SAPIENS; PLASMODIUM FALCIPARUM | homo sapiens | homo sapiens | plasmodium falciparum | Scally, S.W., McLeod, B., Bosch, A., King, C.R., Julien, J.P. | 3.3 | X-RAY DIFFRACTION | 0.280 | 0.230 | false | true | IGHV1 | IGKV2 | Kappa | 0 | -10.077966 | BLI | null | TBD |
3f12 | D | C | 0 | null | null | null | null | IMMUNE SYSTEM | 10/27/08 | Germline V-genes sculpt the binding site of a family of antibodies neutralizing human cytomegalovirus | HOMO SAPIENS | homo sapiens | homo sapiens | null | Thomson, C.A., Bryson, S., McLean, G.R., Creagh, A.L., Pai, E.F., Schrader, J.W. | 2.95 | X-RAY DIFFRACTION | 0.320 | 0.300 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
7ebr | E | F | 0 | C | A | protein | protein | NA | NA | capsid protein vp2 | capsid protein vp1 | VIRUS | 03/10/21 | EV-D68 in complex with 2H12 Fab (state S2) | HUMAN ENTEROVIRUS D68; MUS MUSCULUS | mus musculus | mus musculus | human enterovirus d68 | human enterovirus d68 | Xu, C., Cong, Y. | 3.6 | ELECTRON MICROSCOPY | null | null | false | false | IGHV1 | IGKV9 | Kappa | null | null | null | null | null |
7pqz | A | B | 0 | E | protein | null | spike protein s1 | VIRAL PROTEIN | 09/20/21 | Crystal structure of the receptor binding domain of SARS-CoV-2 Spike glycoprotein in complex with FI-3A and FD-11A Fabs | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Zhou, D., Ren, J., Stuart, D.I. | 3.2 | X-RAY DIFFRACTION | 0.240 | 0.201 | false | true | IGHV3 | IGLV1 | Lambda | null | null | null | null | null |
7orb | A | B | 0 | R | protein | null | spike protein s1 | VIRAL PROTEIN | 06/04/21 | Crystal structure of the L452R mutant receptor binding domain of SARS-CoV-2 Spike glycoprotein in complex with COVOX-75 and COVOX-253 Fabs | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Zhou, D., Ren, J., Stuart, D.I. | 2.5 | X-RAY DIFFRACTION | 0.251 | 0.213 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
7klh | I | M | 0 | B | protein | null | spike glycoprotein | VIRAL PROTEIN/Immune System | 10/30/20 | SARS-CoV-2 RBD in complex with Fab 15033-7 | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Li, Z., Rini, J.M. | 3.0 | X-RAY DIFFRACTION | 0.284 | 0.256 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
4xp5 | H | L | 0 | A | protein | null | dopamine transporter, isoform b | transport protein/inhibitor | 01/16/15 | X-ray structure of Drosophila dopamine transporter bound to cocaine analogue-RTI55 | DROSOPHILA MELANOGASTER; MUS MUSCULUS | mus musculus | mus musculus | drosophila melanogaster | Gouaux, E., Penmatsa, A., Wang, K. | 3.3 | X-RAY DIFFRACTION | 0.286 | 0.245 | false | true | IGHV5 | IGKV4 | Kappa | null | null | null | null | null |
6nis | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 12/31/18 | Crystal structure of a human anti-ZIKV-DENV neutralizing antibody MZ24 isolated following ZPIV vaccination | HOMO SAPIENS | homo sapiens | homo sapiens | null | Sankhala, R.S., Dussupt, V., Donofrio, G., Choe, M., Modjarrad, K., Michael, N.L., Krebs, S.J., Joyce, M.G. | 2.113 | X-RAY DIFFRACTION | 0.200 | 0.165 | false | true | IGHV4 | IGLV1 | Lambda | null | null | null | null | null |
3u79 | null | E | 0 | null | null | null | null | IMMUNE SYSTEM | 10/13/11 | AL-103 Y32F Y96F | HOMO SAPIENS | null | homo sapiens | null | DiCostanzo, A.C., Thompson, J.R., Ramirez-Alvarado, M. | 1.62 | X-RAY DIFFRACTION | 0.223 | 0.169 | false | true | null | IGKV1 | Kappa | null | null | null | null | null |
2vdr | H | L | 0 | A | protein | null | integrin alpha-iib | CELL ADHESION/IMMUNE SYSTEM | 10/10/07 | Integrin AlphaIIbBeta3 Headpiece Bound to Fibrinogen Gamma chain chimera peptide, LGGAKQRGDV | HOMO SAPIENS; MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | homo sapiens | Springer, T., Zhu, J., Xiao, T. | 2.4 | X-RAY DIFFRACTION | 0.193 | 0.148 | false | false | IGHV14 | IGKV14 | Kappa | null | null | null | null | null |
4jfy | H | L | 0 | null | null | null | null | immune system | 02/28/13 | Apo structure of phosphotyrosine (pYAb) scaffold | ESCHERICHIA COLI | null | null | null | Koerber, J.T., Thomsen, N.D., Hannigan, B.T., Degrado, W.F., Wells, J.A. | 2.63 | X-RAY DIFFRACTION | 0.236 | 0.188 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
7ki6 | G | F | 0 | E | protein | null | fusion glycoprotein f0 | VIRAL PROTEIN/IMMUNE SYSTEM | 10/23/20 | Structure of the HeV F glycoprotein in complex with the 1F5 neutralizing antibody | HENDRA HENIPAVIRUS; MUS MUSCULUS | mus musculus | mus musculus | hendra henipavirus | Dang, H.V., Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D. | 2.8 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV4 | Kappa | null | null | null | null | null |
6ww2 | K | null | 0 | null | null | null | null | MEMBRANE PROTEIN | 05/07/20 | Structure of human Frizzled5 by fiducial-assisted cryo-EM | HOMO SAPIENS; SYNTHETIC CONSTRUCT; ESCHERICHIA COLI | synthetic construct | null | null | Tsutsumi, N., Jude, K.M., Gati, C., Garcia, K.C. | 3.7 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
4ot1 | H | L | 0 | A | protein | null | envelope glycoprotein b | VIRAL PROTEIN/IMMUNE SYSTEM | 02/13/14 | Structural Basis for the Recognition of Human Cytomegalovirus Glycoprotein B by the Neutralizing Human Antibody SM5-1 | HOMO SAPIENS; HUMAN CYTOMEGALOVIRUS | homo sapiens | homo sapiens | human cytomegalovirus | Diestel, U., Muller, Y.A. | 2.11 | X-RAY DIFFRACTION | 0.231 | 0.171 | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
2kqm | null | A | 1 | null | null | null | null | IMMUNE SYSTEM | 11/11/09 | Solution structure of the KI O18/O8 Y87H immunoglobulin light chain variable domain | HOMO SAPIENS | null | homo sapiens | null | Volkman, B.F., Peterson, F.C., Ramirez-Alvarado, M., Baden, E.M. | NOT | SOLUTION NMR | null | null | false | true | null | IGKV1 | Kappa | null | null | null | null | null |
1vhp | A | null | 15 | null | null | null | null | IMMUNOGLOBULIN | 04/16/96 | VH-P8, NMR | HOMO SAPIENS | homo sapiens | null | null | Riechmann, L. | NOT | SOLUTION NMR | null | null | false | true | unknown | unknown | unknown | null | null | null | null | null |
7ki4 | D | C | 0 | B | protein | null | fusion glycoprotein f0 | VIRAL PROTEIN/IMMUNE SYSTEM | 10/23/20 | Structure of the NiV F glycoprotein in complex with the 12B2 neutralizing antibody | NIPAH VIRUS; MUS MUSCULUS | mus musculus | mus musculus | nipah virus | Dang, H.V., Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D. | 2.9 | ELECTRON MICROSCOPY | null | null | false | true | IGHV2 | IGKV12 | Kappa | null | null | null | null | null |
1maj | null | A | 7 | null | null | null | null | IMMUNOGLOBULIN | 09/16/93 | SOLUTION STRUCTURE OF AN ISOLATED ANTIBODY VL DOMAIN | MUS MUSCULUS | null | mus musculus | null | Constantine, K.L., Friedrichs, M.S., Metzler, W.J., Wittekind, M., Hensley, P., Mueller, L. | NOT | SOLUTION NMR | null | null | false | true | unknown | unknown | unknown | null | null | null | null | null |
6y9b | I | M | 0 | A | protein | null | metalloreductase steap1 | MEMBRANE PROTEIN | 05/20/20 | Cryo-EM structure of trimeric human STEAP1 bound to three Fab120.545 fragments | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | Oosterheert, W., Gros, P. | 2.97 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV8 | Kappa | null | null | null | null | null |
3q6f | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 12/31/10 | Crystal structure of Fab of human mAb 2909 specific for quaternary neutralizing epitope of HIV-1 gp120 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Spurrier, B., Sampson, J., Totrov, M., Li, H., O'Neal, T., William, C., Robinson, J., Gorny, M.K., Zolla-Pazner, S., Kong, X.P. | 3.192 | X-RAY DIFFRACTION | 0.243 | 0.199 | false | false | IGHV3 | IGLV3 | Lambda | null | null | null | null | null |
7uap | H | L | 0 | A | protein | null | spike glycoprotein | VIRAL PROTEIN | 03/13/22 | Structure of the SARS-CoV-2 S 6P trimer in complex with the neutralizing antibody Fab fragment, C1520 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Barnes, C.O. | 2.8 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGLV4 | Lambda | null | null | null | null | null |
4nbx | B | null | 0 | A | protein | null | tcda | IMMUNE SYSTEM | 10/23/13 | Crystal Structure of Clostridium difficile Toxin A fragment TcdA-A1 Bound to A20.1 VHH | CLOSTRIDIUM DIFFICILE; LAMA GLAMA | lama glama | null | clostridium difficile | Murase, T., Eugenio, L., Schorr, M., Hussack, G., Tanha, J., Kitova, E.N., Klassen, J.S., Ng, K.K.S. | 1.75 | X-RAY DIFFRACTION | 0.229 | 0.195 | false | true | IGHV1 | null | null | null | null | null | null | null |
6wgj | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 04/05/20 | Fab portion of dupilumab with Crystal Kappa design and no interchain disulfide | HOMO SAPIENS | homo sapiens | homo sapiens | null | Druzina, Z., Atwell, S., Pustilnik, A., Antonysamy, S., Ho, C., Lieu, R., Hendle, J., Benach, J., Wang, J. | 1.9 | X-RAY DIFFRACTION | 0.289 | 0.235 | false | true | IGHV3 | IGKV2 | Kappa | null | null | null | null | null |
4yaq | H | L | 0 | L | carbohydrate | NAG | polysaccharide | IMMUNE SYSTEM | 02/17/15 | Crystal structure of a computationally optimized PG9 mutant | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Murrell, S., Julien, J.P., Wilson, I.A. | 2.3 | X-RAY DIFFRACTION | 0.238 | 0.204 | false | true | IGHV3 | IGLV2 | Lambda | null | null | null | null | null |
1i8m | H | L | 0 | T | nucleic-acid | null | 5'-d(*tp*tp*tp*tp*t)-3' | IMMUNE SYSTEM/DNA | 03/14/01 | CRYSTAL STRUCTURE OF A RECOMBINANT ANTI-SINGLE-STRANDED DNA ANTIBODY FRAGMENT COMPLEXED WITH DT5 | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | null | Tanner, J.J., Komissarov, A.A., Deutscher, S.L. | 2.1 | X-RAY DIFFRACTION | 0.258 | 0.220 | false | true | IGHV1 | IGKV12 | Kappa | 0.000003 | -7.596979 | Unknown | null | TBD |
4jfx | H | L | 0 | P | peptide | null | phosphopeptide | immune system | 02/28/13 | Structure of phosphotyrosine (pTyr) scaffold bound to pTyr peptide | ESCHERICHIA COLI; SYNTHETIC CONSTRUCT | null | null | null | Koerber, J.T., Thomsen, N.D., Hannigan, B.T., Degrado, W.F., Wells, J.A. | 1.95 | X-RAY DIFFRACTION | 0.202 | 0.163 | false | true | IGHV3 | IGKV3 | Kappa | 0 | -8.790776 | Unknown | null | TBD |
6ir2 | B | null | 0 | A | protein | null | mcherry fluorescent protein | FLUORESCENT PROTEIN | 11/09/18 | Crystal structure of red fluorescent protein mCherry complexed with the nanobody LaM2 at 1.4 Angstron resolution | ANAPLASMA MARGINALE; CAMELUS BACTRIANUS | camelus bactrianus | null | anaplasma marginale | Ding, Y., Wang, Z.Y., Hu, R.T., Chen, X. | 1.393 | X-RAY DIFFRACTION | 0.216 | 0.195 | false | true | IGHV1 | null | null | null | null | null | null | null |
3u79 | null | D | 0 | null | null | null | null | IMMUNE SYSTEM | 10/13/11 | AL-103 Y32F Y96F | HOMO SAPIENS | null | homo sapiens | null | DiCostanzo, A.C., Thompson, J.R., Ramirez-Alvarado, M. | 1.62 | X-RAY DIFFRACTION | 0.223 | 0.169 | false | true | null | IGKV1 | Kappa | null | null | null | null | null |
6nb5 | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 12/06/18 | Crystal structure of anti- MERS-CoV human neutralizing LCA60 antibody Fab fragment | HOMO SAPIENS | homo sapiens | homo sapiens | null | Walls, A.J., Xiong, X., Park, Y.J., Tortorici, M.A., Snijder, J., Quispe, J., Cameroni, E., Gopal, R., Dai, M., Lanzavecchia, A., Zambon, M., Rey, F.A., Corti, D., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 3.0 | X-RAY DIFFRACTION | 0.283 | 0.228 | false | true | IGHV3 | IGLV2 | Lambda | null | null | null | null | null |
6pxh | H | L | 0 | B | protein | null | mers-cov s1-ntd | IMMUNE SYSTEM/Viral protein | 07/26/19 | Crystal Structure of MERS-CoV S1-NTD bound with G2 Fab | MIDDLE EAST RESPIRATORY SYNDROME-RELATED CORONAVIRUS; MUS MUSCULUS | mus musculus | mus musculus | middle east respiratory syndrome-relatedcoronavirus | Wang, N., McLellan, J.S. | 2.3 | X-RAY DIFFRACTION | 0.213 | 0.180 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
3eyv | H | L | 0 | H | carbohydrate | FUC | polysaccharide | IMMUNE SYSTEM | 10/22/08 | Anti-Lewis Y Fab fragment with Lewis Y antigen in the presence of zinc ions | MUS MUSCULUS, HOMO SAPIENS | mus musculus, homo sapiens | mus musculus, homo sapiens | mus musculus, homo sapiens | Farrugia, W., Scott, A.M., Ramsland, P.A. | 2.5 | X-RAY DIFFRACTION | 0.262 | 0.210 | false | true | IGHV5 | IGKV1 | Kappa | null | null | null | null | null |
1mre | H | L | 0 | L | nucleic-acid | GDP | GUANOSINE-5'-DIPHOSPHATE | IMMUNOGLOBULIN | 06/13/94 | PREPARATION, CHARACTERIZATION AND CRYSTALLIZATION OF AN ANTIBODY FAB FRAGMENT THAT RECOGNIZES RNA. CRYSTAL STRUCTURES OF NATIVE FAB AND THREE FAB-MONONUCLEOTIDE COMPLEXES | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Pokkuluri, P.R., Cygler, M. | 2.3 | X-RAY DIFFRACTION | unknown | 0.192 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
5d72 | H | L | 0 | A | protein | null | granulocyte-macrophage colony-stimulating factor | IMMUNE SYSTEM | 08/13/15 | Crystal structure of MOR04252, a neutralizing anti-human GM-CSF antibody Fab fragment in complex with human GM-CSF | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Eylenstein, R., Weinfurtner, D., Steidl, S., Boettcher, J., Augustin, M. | 2.6 | X-RAY DIFFRACTION | 0.266 | 0.232 | false | true | IGHV3 | IGLV3 | Lambda | 0 | -15.309341 | Unknown | null | TBD |
3ck0 | H | L | 0 | P | peptide | null | protein (8-mer; human angiotensin ii) | IMMUNE SYSTEM | 06/14/99 | ANTI-ANTI-IDIOTYPIC ANTIBODY AGAINST HUMAN ANGIOTENSIN II, COMPLEX WITH HUMAN ANGIOTENSIN II | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | synthetic construct | Pan, Y.H., Amzel, L.M. | 3.0 | X-RAY DIFFRACTION | unknown | 0.200 | false | false | IGHV10 | IGKV8 | Kappa | null | null | null | null | null |
6w7y | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 03/19/20 | Crystal structure of SARS-CoV and SARS-CoV-2 reactive human antibody CR3022 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Chen, W.H., Joyce, M.G. | 3.3 | X-RAY DIFFRACTION | 0.278 | 0.252 | false | true | IGHV5 | IGKV4 | Kappa | null | null | null | null | null |
6c5v | H | L | 0 | A | C | B | protein | protein | protein | NA | NA | NA | envelope glycoprotein h | glycoprotein 42 | envelope glycoprotein l | VIRAL PROTEIN | 01/16/18 | An anti-gH/gL antibody that neutralizes dual-tropic infection defines a site of vulnerability on Epstein-Barr virus | HUMAN HERPESVIRUS 4; HOMO SAPIENS | homo sapiens | homo sapiens | human herpesvirus 4 | human herpesvirus 4 | human herpesvirus 4 | Snijder, J., Ortego, M.S., Weidle, C., Stuart, A.B., Gray, M.A., McElrath, M.J., Pancera, M., Veesler, D., McGuire, A.T., Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 4.8 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGLV3 | Lambda | null | null | null | null | null |
1j1p | H | L | 0 | Y | protein | null | lysozyme c | IMMUNE SYSTEM/HYDROLASE | 12/13/02 | Crystal structure of HyHEL-10 Fv mutant LS91A complexed with hen egg white lysozyme | MUS MUSCULUS; GALLUS GALLUS | mus musculus | mus musculus | gallus gallus | Yokota, A., Tsumoto, K., Shiroishi, M., Kondo, H., Kumagai, I. | 1.8 | X-RAY DIFFRACTION | 0.212 | 0.191 | false | true | IGHV3 | IGKV5 | Kappa | null | null | null | null | null |
5utf | H | L | 0 | G | protein | null | envelope glycoprotein gp120 | IMMUNE SYSTEM | 02/14/17 | Crystal Structure of a Stabilized DS-SOSIP.6mut BG505 gp140 HIV-1 Env Trimer, Containing Mutations I201C-P433C (DS), L154M, Y177W, N300M, N302M, T320L, I420M in Complex with Human Antibodies PGT122 and 35O22 at 4.3 A | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Pancera, M., Chuang, G.-Y., Xu, K., Kwong, P.D. | 3.503 | X-RAY DIFFRACTION | 0.299 | 0.216 | false | true | IGHV4 | IGLV3 | Lambda | null | null | null | null | null |
7kml | H | L | 0 | A | protein | null | spike glycoprotein | Viral protein/Immune System | 11/03/20 | cryo-EM structure of SARS-CoV-2 spike in complex with Fab 15033-7, three RBDs bound | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Li, Z., Rini, J.M. | 3.8 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
7x6l | G | J | 0 | E | A | protein | protein | NA | NA | hemagglutinin | hemagglutinin | STRUCTURAL PROTEIN | 03/07/22 | Cryo-EM structure of H3 hemagglutinin from A/HongKong/01/1968 in complex with a neutralizing antibody 28-12 | HOMO SAPIENS; INFLUENZA A VIRUS (A/HONG KONG/1/1968(H3N2)); INFLUENZA A VIRUS | homo sapiens | homo sapiens | influenza a virus | influenza a virus (a/hong kong/1/1968(h3n2)) | Cong, Y., Liu, C.X. | 3.7 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
5bv7 | H | L | 0 | A | protein | null | phosphatidylcholine-sterol acyltransferase | HYDROLASE/IMMUNE SYSTEM | 06/04/15 | Crystal structure of human LCAT (L4F, N5D) in complex with Fab of an agonistic antibody | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Piper, D.E., Romanow, W.G., Thibault, S.T., Walker, N.P.C. | 2.45 | X-RAY DIFFRACTION | 0.242 | 0.189 | false | false | IGHV4 | IGLV3 | Lambda | null | null | null | null | null |
5mhr | I | H | 0 | B | protein | null | viral attachment protein sigma 1 | IMMUNE SYSTEM | 11/25/16 | T3D reovirus sigma1 complexed with 9BG5 Fab fragments | REOVIRUS SP.; MUS MUSCULUS | mus musculus | mus musculus | reovirus sp. | Stehle, T., Dietrich, M.H. | 3.0 | X-RAY DIFFRACTION | 0.247 | 0.212 | false | false | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
2kh2 | B | b | 9 | A | protein | null | interleukin-1 beta | Cytokine/IMMUNE SYSTEM | 03/23/09 | Solution structure of a scFv-IL-1B complex | HOMO SAPIENS; MUS MUSCULUS | mus musculus | null | homo sapiens | Wilkinson, I.C., Hall, C.J., Veverka, V., Muskett, F.W., Stephens, P.E., Taylor, R.J., Henry, A.J., Carr, M.D. | NOT | SOLUTION NMR | null | null | true | true | unknown | unknown | unknown | null | null | null | null | null |
6u0l | H | L | 0 | A | protein | null | envelope glycoprotein gp160 | VIRAL PROTEIN | 08/14/19 | Asymmetrically open conformational state (Class I) of HIV-1 Env trimer BG505 SOSIP.664 in complex with sCD4 and E51 Fab | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Yang, Z., Bjorkman, P.J. | 3.3 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
4s2s | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 01/22/15 | Crystal Structure of Fab fragment of monoclonal antibody RoAb13 | MUS MUSCULUS | mus musculus | mus musculus | null | Chain, B., Arnold, J., Akthar, S., Noursadeghi, M., Lapp, T., Ji, C., Naider, D., Zhang, Y., Govada, L., Saridakis, E., Chayen, N.E. | 2.1 | X-RAY DIFFRACTION | 0.234 | 0.186 | false | false | IGHV5 | IGKV8 | Kappa | null | null | null | null | null |
7rg9 | E | e | 0 | A | B | protein | protein | NA | NA | isoform gnas-2 of guanine nucleotide-binding protein g(s)subunit alpha isoforms short | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | MEMBRANE PROTEIN | 07/14/21 | cryo-EM of human Glucagon-like peptide 1 receptor GLP-1R in apo form | HOMO SAPIENS; MUS MUSCULUS; LAMA GLAMA | mus musculus | null | homo sapiens | homo sapiens | Sun, B., Kobilka, B.K., Sloop, K.W., Feng, D., Kobilka, T.S. | 3.2 | ELECTRON MICROSCOPY | null | null | true | true | unknown | unknown | unknown | null | null | null | null | null |
6fzr | H | h | 0 | P | peptide | null | mucin-1 | IMMUNE SYSTEM | 03/15/18 | Crystal structure of scFv-SM3 in complex with compound 2 | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | null | homo sapiens | Bermejo, I.A., Usabiaga, I., Companon, I., Castro-Lopez, J., Insausti, A., Fernandez, J.A., Avenoza, A., Busto, J.H., Jimenez-Barbero, J., Asensio, J.L., Jimenez-Oses, G., Peregrina, J.M., Hurtado-Guerrero, R., Cocinero, E.J., Corzana, F. | 1.8 | X-RAY DIFFRACTION | 0.232 | 0.187 | true | true | unknown | unknown | unknown | null | null | null | null | null |
5w5z | H | L | 0 | A | protein | null | apoptosis regulator bax | APOPTOSIS | 06/16/17 | Crystal structure of BAXP168G in complex with an activating antibody at high resolution | HOMO SAPIENS; RATTUS NORVEGICUS | rattus norvegicus | rattus norvegicus | homo sapiens | Robin, A.Y., Colman, P.M., Czabotar, P.E. | 1.997 | X-RAY DIFFRACTION | 0.268 | 0.217 | false | false | IGHV1 | IGKV22 | Kappa | null | null | null | null | null |
6i1o | H | L | 0 | null | null | null | null | PROTEIN BINDING | 10/29/18 | Fab fragment of an antibody selective for wild-type alpha-1-antitrypsin | MUS MUSCULUS | mus musculus | mus musculus | null | Laffranchi, M., Elliston, E.L.K., Miranda, E., Perez, J., Fra, A., Lomas, D.A., Irving, J.A. | 1.93 | X-RAY DIFFRACTION | 0.235 | 0.199 | false | false | IGHV5 | IGKV14 | Kappa | null | null | null | null | null |
5nhr | H | L | 0 | C | protein | null | activin receptor type-2b | IMMUNE SYSTEM | 03/22/17 | CRYSTAL STRUCTURE OF THE Activin receptor type-2B LIGAND BINDING DOMAIN IN COMPLEX WITH BIMAGRUMAB FV, CUBIC CRYSTAL FORM | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | RONDEAU, J.-M. | 3.35 | X-RAY DIFFRACTION | 0.229 | 0.216 | false | true | IGHV1 | IGLV2 | Lambda | null | null | null | null | null |
7mfb | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 04/08/21 | Crystal structure of antibody 10E8v4 Fab - light chain H31F variant | HOMO SAPIENS | homo sapiens | homo sapiens | null | Kwon, Y.D., Kwong, P.D. | 1.74 | X-RAY DIFFRACTION | 0.246 | 0.223 | false | true | IGHV3 | IGLV3 | Lambda | null | null | null | null | null |
3chn | C | O | 7 | null | null | null | null | IMMUNE SYSTEM | 03/10/08 | Solution structure of human secretory IgA1 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Bonner, A., Almogren, A., Furtado, P.B., Kerr, M.A., Perkins, S.J. | NOT | SOLUTION SCATTERING / HOMOLOGY MODEL | null | null | false | false | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
1q9k | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 08/25/03 | S25-2 Fab Unliganded 1 | MUS MUSCULUS | mus musculus | mus musculus | null | Nguyen, H.P., Seto, N.O., MacKenzie, C.R., Brade, L., Kosma, P., Brade, H., Evans, S.V. | 1.96 | X-RAY DIFFRACTION | 0.278 | 0.228 | false | false | IGHV7 | IGKV8 | Kappa | null | null | null | null | null |
5e8e | B | A | 0 | H | protein | null | thrombin heavy chain | IMMUNE SYSTEM/HYDROLASE | 10/14/15 | Crystal structure of thrombin bound to an exosite 1-specific IgA Fab | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Baglin, T.P., Langdown, J., Frasson, R., Huntington, J.A. | 1.9 | X-RAY DIFFRACTION | 0.244 | 0.201 | false | false | IGHV1 | IGKV3 | Kappa | 0 | -11.929943 | SPR | null | TBD |
6gkd | C | null | 0 | A | protein | null | cystic fibrosis transmembrane conductance regulator | HYDROLASE | 05/18/18 | human NBD1 of CFTR in complex with nanobodies D12 and G3a | HOMO SAPIENS; LAMA GLAMA | lama glama | null | homo sapiens | Sigoillot, M., Overtus, M., Grodecka, M., Scholl, D., Garcia-Pino, A., Laeremans, T., He, L., Pardon, E., Hildebrandt, E., Urbatsch, I., Steyaert, J., Riordan, J.R., Govaerts, C. | 2.99 | X-RAY DIFFRACTION | 0.235 | 0.204 | false | true | IGHV1 | null | null | null | null | null | null | null |
7chh | D | E | 0 | A | protein | null | spike glycoprotein | ANTIVIRAL PROTEIN/IMMUNE SYSTEM | 07/05/20 | Cryo-EM structure of the SARS-CoV-2 S-6P in complex with BD-368-2 Fabs | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Xiao, J., Zhu, Q., Wang, G. | 3.49 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV2 | Kappa | null | null | null | null | null |
6dc4 | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 05/04/18 | RSV-neutralizing human antibody AM22 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Jones, H.G., McLellan, J.S. | 1.7 | X-RAY DIFFRACTION | 0.205 | 0.180 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
6nmr | H | L | 0 | S | protein | null | tyrosine-protein phosphatase non-receptor type substrate 1 | IMMUNE SYSTEM | 01/11/19 | Blocking Fab 119 anti-SIRP-alpha antibody in complex with SIRP-alpha Variant 1 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Wibowo, A.S., Carter, J.J., Sim, J. | 2.42 | X-RAY DIFFRACTION | 0.323 | 0.289 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
4ubd | O | P | 0 | N | Q | protein | protein | NA | NA | hemagglutinin ha2 chain | hemagglutinin ha1 chain | viral protein/immune system | 08/12/14 | Crystal structure of a neutralizing human monoclonal antibody with 1968 H3 HA | INFLUENZA A VIRUS; HOMO SAPIENS | homo sapiens | homo sapiens | influenza a virus | influenza a virus | Shore, D.A., Yang, H., Cho, M., Donis, R.O., Stevens, J. | 3.5 | X-RAY DIFFRACTION | 0.258 | 0.212 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
6w73 | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 03/18/20 | Fab Structure of CD4 Binding Site (CD4bs) Huamn Monoclonal Antibody HmAb64 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Kong, X., Pan, R. | 2.8 | X-RAY DIFFRACTION | 0.263 | 0.178 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
1v7n | H | L | 0 | V | protein | null | thrombopoietin | IMMUNE SYSTEM/CYTOKINE | 12/18/03 | Human Thrombopoietin Functional Domain Complexed To Neutralizing Antibody TN1 Fab | MUS MUSCULUS; HOMO SAPIENS | mus musculus | mus musculus | homo sapiens | Feese, M.D., Tamada, T., Kato, Y., Maeda, Y., Hirose, M., Matsukura, Y., Shigematsu, H., Kato, T., Miyazaki, H., Kuroki, R. | 3.3 | X-RAY DIFFRACTION | 0.305 | 0.167 | false | true | IGHV6 | IGKV4 | Kappa | null | null | null | null | null |
6k7o | B | C | 0 | P | protein | null | leukocyte immunoglobulin-like receptor subfamily b member4 | IMMUNE SYSTEM | 06/08/19 | Complex structure of LILRB4 and h128-3 antibody | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Song, H., Chai, Y., Xu, X., Gao, F.G. | 3.004 | X-RAY DIFFRACTION | 0.270 | 0.228 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
4nrx | H | L | 0 | P | peptide | null | envelope glycoprotein gp41 | IMMUNE SYSTEM | 11/27/13 | Crystal Structure of HIV-1 Neutralizing Antibody m66 in complex with gp41 MPER peptide | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Ofek, G., Yang, Y., Kwong, P.D. | 2.21 | X-RAY DIFFRACTION | 0.215 | 0.188 | false | true | IGHV5 | IGKV1 | Kappa | null | null | null | null | null |
4rrp | K | E | 0 | Q | protein | null | antigen asf1p | IMMUNE SYSTEM | 11/06/14 | Crystal Structure of the Fab complexed with antigen Asf1p, Northeast Structural Genomics Consortium (NESG) Target PdR16 | HOMO SAPIENS; SACCHAROMYCES CEREVISIAE | homo sapiens | homo sapiens | saccharomyces cerevisiae | Kuzin, A., Lew, S., Seetharaman, J., Mao, L., Xiao, R., Oconnell, P.T., Maglaqui, M., Bailey, L., Everett, J.K., Acton, T.B., Montelione, G.T., Hunt, J.F., Tong, L., Chaperone-Enabled Studies of Epigenetic Regulation Enzymes (CEBS), Northeast Structural Genomics Consortium (NESG) | 2.79 | X-RAY DIFFRACTION | 0.253 | 0.183 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
1tzh | B | A | 0 | W | protein | null | vascular endothelial growth factor a | immune system | 07/09/04 | Crystal Structure of the Fab YADS1 Complexed with h-VEGF | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | Fellouse, F.A., Wiesmann, C., Sidhu, S.S. | 2.6 | X-RAY DIFFRACTION | 0.271 | 0.212 | false | true | IGHV5 | IGKV12 | Kappa | 0 | -12.4 | SPR | 37 | 15306681 |
3aaz | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 11/28/09 | Crystal structure of the humanized recombinant Fab fragment of a murine; antibody | HOMO SAPIENS | homo sapiens | homo sapiens | null | Streltsov, V.A. | 2.2 | X-RAY DIFFRACTION | 0.271 | 0.209 | false | true | IGHV2 | IGKV2 | Kappa | null | null | null | null | null |
6ukt | D | null | 0 | A | protein | null | resistance to inhibitors of cholinesterase 8 homolog a (c.elegans) | SIGNALING PROTEIN | 10/05/19 | Cryo-EM structure of mammalian Ric-8A:Galpha(i):nanobody complex | RATTUS NORVEGICUS; LAMA GLAMA | lama glama | null | rattus norvegicus | Mou, T.C., Zhang, K., Johnston, J.D., Chiu, W., Sprang, S.R. | 3.87 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
3cm9 | C | N | 5 | null | null | null | null | IMMUNE SYSTEM | 03/21/08 | Solution Structure of Human SIgA2 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Bonner, A., Almogren, A., Furtado, P.B., Kerr, M.A., Perkins, S.J. | NOT | SOLUTION SCATTERING | null | null | false | false | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
7sn3 | H | L | 0 | C | protein | null | spike glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 10/27/21 | Structure of human SARS-CoV-2 spike glycoprotein trimer bound by neutralizing antibody C1C-A3 Fab (variable region) | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Pan, J., Abraham, J., Shankar, S. | 3.1 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
7x7e | E | null | 0 | F | protein | null | spike protein s1 | VIRAL PROTEIN/IMMUNE SYSTEM | 03/09/22 | SARS-CoV-2 RBD and Nb22 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; LAMA | lama | null | severe acute respiratory syndrome coronavirus2 | Wang, Y., Ye, S. | 2.67 | X-RAY DIFFRACTION | 0.250 | 0.205 | false | true | IGHV1 | null | null | null | null | null | null | null |
5j13 | C | B | 0 | A | protein | null | thymic stromal lymphopoietin | IMMUNE SYSTEM | 03/28/16 | Cytokine antibody complex | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Verstraete, K., Savvides, S.N. | 2.298 | X-RAY DIFFRACTION | 0.215 | 0.189 | false | true | IGHV3 | IGLV3 | Lambda | 0 | -13.945097 | SPR | null | TBD |
7lua | h | g | 0 | M | carbohydrate | MAN | ALPHA-D-MANNOSE | VIRAL PROTEIN/IMMUNE SYSTEM | 02/21/21 | Cryo-EM structure of DH898.1 Fab-dimer bound near the CD4 binding site of HIV-1 Env CH848 SOSIP trimer | HUMAN IMMUNODEFICIENCY VIRUS 1; SIMIAN-HUMAN IMMUNODEFICIENCY VIRUS; HOMO SAPIENS | homo sapiens | homo sapiens | null | Manne, K., Edwards, R.J., Acharya, P. | 4.7 | ELECTRON MICROSCOPY | null | null | false | false | unknown | IGKV2 | Kappa | null | null | null | null | null |
5kov | O | o | 0 | M | protein | null | capsid polyprotein vp90 | VIRAL PROTEIN | 07/01/16 | Crystal structure of the human astrovirus 2 capsid protein spike in complex with a single chain variable fragment of an astrovirus neutralizing antibody at 3.24-A resolution | HUMAN ASTROVIRUS-2; MUS MUSCULUS | mus musculus | null | human astrovirus-2 | Bogdanoff, W.A., DuBois, R.M. | 3.245 | X-RAY DIFFRACTION | 0.288 | 0.241 | true | true | unknown | unknown | unknown | 0 | -11.907338 | SPR | null | TBD |
2ykl | H | L | 0 | H | Hapten | NLD | NICOTINE-11-YL-METHYL-(4-ETHYLAMINO-4-OXO)-BUTANOATE | IMMUNE SYSTEM | 05/27/11 | Structure of human anti-nicotine Fab fragment in complex with nicotine-11-yl-methyl-(4-ethylamino-4-oxo)-butanoate | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Tars, K., Kotelovica, S., Lipowsky, G., Bauer, M., Beerli, R., Bachmann, M., Maurer, P. | 2.1 | X-RAY DIFFRACTION | 0.27404 | 0.21352 | false | true | IGHV4 | IGLV1 | Lambda | null | null | null | null | null |
7anq | B | null | 0 | A | protein | null | proprotein convertase subtilisin/kexin type 9 | HYDROLASE | 10/12/20 | Complete PCSK9 C-ter domain in complex with VHH P1.40 | HOMO SAPIENS; LAMA GLAMA | lama glama | null | homo sapiens | Ciccone, L., Legrand, P., Stura, E.A., Dive, V., Seidahn, N.G., Fruchart Gaillard, C. | 2.2 | X-RAY DIFFRACTION | 0.256 | 0.213 | false | true | IGHV1 | null | null | null | null | null | null | null |
5n7w | H | L | 0 | X | protein | null | interleukin-17a | IMMUNE SYSTEM | 02/21/17 | Computationally designed functional antibody | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Hargreaves, D., Breed, J. | 1.96 | X-RAY DIFFRACTION | 0.250 | 0.199 | false | true | IGHV1 | IGKV1 | Kappa | 0 | -9.681918 | SPR | null | TBD |
7rtp | null | B | 0 | B | Hapten | NY9 | N-{2-[7-(diethylamino)-4-methyl-2-oxo-2H-1-benzopyran-3-yl]ethyl}-N'-[(pyridin-3-yl)methyl]urea | IMMUNE SYSTEM | 08/13/21 | Structure of full-length human lambda-6A light chain JTO in complex with urea stabilizer 20 [1-(2-(7-(diethylamino)-4-methyl-2-oxo-2H-chromen-3-yl)ethyl)-3-(pyridin-3-ylmethyl)urea] | HOMO SAPIENS | null | homo sapiens | homo sapiens | Yan, N.L., Wilson, I.A., Kelly, J.W. | 2.09 | X-RAY DIFFRACTION | 0.238 | 0.179 | false | true | null | IGLV6 | Lambda | null | null | null | null | null |
6zbp | F | null | 0 | E | protein | null | unknown | ANTIVIRAL PROTEIN | 06/08/20 | H11-H4 complex with SARS-CoV-2 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; LAMA GLAMA | null | null | null | Naismith, J.H., Huo, J., Mikolajek, H., Ward, P., Dumoux, M., Owens, R.J., LeBas, A. | 1.85 | X-RAY DIFFRACTION | 0.217 | 0.185 | false | false | IGHV1 | null | null | null | null | null | null | null |
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