pdb stringlengths 4 4 | Hchain stringclasses 59
values | Lchain stringclasses 60
values | model int64 0 76 | antigen_chain stringclasses 386
values | antigen_type stringclasses 24
values | antigen_het_name stringclasses 240
values | antigen_name stringlengths 1 396 ⌀ | short_header stringclasses 448
values | date stringlengths 8 8 | compound stringlengths 4 243 | organism stringlengths 3 175 ⌀ | heavy_species stringclasses 121
values | light_species stringclasses 67
values | antigen_species stringclasses 937
values | authors stringlengths 6 762 | resolution stringlengths 1 8 | method stringclasses 10
values | r_free stringclasses 354
values | r_factor stringclasses 342
values | scfv bool 2
classes | engineered bool 2
classes | heavy_subclass stringclasses 14
values | light_subclass stringclasses 35
values | light_ctype stringclasses 3
values | affinity float64 0 0 ⌀ | delta_g float64 -16.91 -5.04 ⌀ | affinity_method stringclasses 11
values | temperature float64 4 37 ⌀ | pmid stringclasses 157
values |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
3mug | H | G | 0 | null | null | null | null | IMMUNE SYSTEM | 05/03/10 | Crystal structure of human Fab PG16, a broadly reactive and potent HIV-1 neutralizing antibody | HOMO SAPIENS | homo sapiens | homo sapiens | null | Pejchal, R., Walker, L.M., Burton, D.R., Wilson, I.A. | 2.49 | X-RAY DIFFRACTION | 0.248 | 0.207 | false | true | IGHV3 | IGLV2 | Lambda | null | null | null | null | null |
5wl2 | A | B | 0 | null | null | null | null | ANTIVIRAL PROTEIN | 07/25/17 | VH1-69 germline antibody with CDR H3 sequence of CR9114 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Wilson, I.A., Lang, S. | 2.0 | X-RAY DIFFRACTION | 0.236 | 0.200 | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
1fve | D | C | 0 | null | null | null | null | IMMUNOGLOBULIN | 10/20/92 | X-RAY STRUCTURES OF THE ANTIGEN-BINDING DOMAINS FROM THREE VARIANTS OF HUMANIZED ANTI-P185-HER2 ANTIBODY 4D5 AND COMPARISON WITH MOLECULAR MODELING | HOMO SAPIENS | homo sapiens | homo sapiens | null | Eigenbrot, C., Randal, M., Presta, L., Kossiakoff, A.A. | 2.7 | X-RAY DIFFRACTION | unknown | 0.171 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
4g6m | H | L | 0 | A | protein | null | interleukin-1 beta | IMMUNE SYSTEM | 07/19/12 | Crystal strucure of human IL-1beta in complex with therapeutic antibody binding fragment of gevokizumab | null | homo sapiens | homo sapiens | homo sapiens | Blech, M., Hoerer, S. | 1.81 | X-RAY DIFFRACTION | 0.226 | 0.202 | false | true | IGHV4 | IGKV1 | Kappa | 0 | -13.011617 | SPR | null | TBD |
5jw3 | H | L | 0 | B | A | protein | protein | NA | NA | hemagglutinin | hemagglutinin | IMMUNE SYSTEM | 05/11/16 | Structure of MEDI8852 Fab Fragment in Complex with H7 HA | HOMO SAPIENS; INFLUENZA A VIRUS (A/TURKEY/ITALY/214845/2002(H7N3)) | homo sapiens | homo sapiens | influenza a virus(a/turkey/italy/214845/2002(h7n3)) | influenza a virus(a/turkey/italy/214845/2002(h7n3)) | Collins, P.J., Neu, U., Walker, P.A., Vorlaender, M.K., Ogrodowicz, R.W., Martin, S.R., Gamblin, S.J., Skehel, J.J. | 3.75 | X-RAY DIFFRACTION | 0.263 | 0.224 | false | true | IGHV6 | IGKV1 | Kappa | null | null | null | null | null |
4zfo | A | B | 0 | F | peptide | null | tumor necrosis factor receptor superfamily member 17 | IMMUNE SYSTEM | 04/21/15 | J22.9-xi: chimeric mouse/human antibody against human BCMA (CD269) | MUS MUSCULUS; HOMO SAPIENS | mus musculus | mus musculus | homo sapiens | Marino, S.F., Daumke, O., Olal, D. | 1.895 | X-RAY DIFFRACTION | 0.209 | 0.176 | false | true | IGHV4 | IGKV6 | Kappa | 0 | -14.567099 | Unknown | null | TBD |
6wgl | A | B | 0 | C | protein | null | interleukin-4 receptor subunit alpha | IMMUNE SYSTEM | 04/05/20 | Dupilumab fab with Crystal Kappa design complexed with human IL-4 receptor | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Druzina, Z., Atwell, S., Pustilnik, A., Antonysamy, S., Ho, C., Lieu, R., Hendle, J., Benach, J., Wang, J. | 2.82 | X-RAY DIFFRACTION | 0.304 | 0.245 | false | true | IGHV3 | IGKV2 | Kappa | null | null | null | null | null |
6ao0 | H | null | 0 | null | null | null | null | IMMUNE SYSTEM | 08/15/17 | CAT192 Fab Insertion Mutant H2/L2 | HOMO SAPIENS | homo sapiens | null | null | Lord, D.M., Wei, R.R. | 2.35 | X-RAY DIFFRACTION | 0.261 | 0.206 | false | true | IGHV3 | null | null | null | null | null | null | null |
3cm9 | C | N | 3 | null | null | null | null | IMMUNE SYSTEM | 03/21/08 | Solution Structure of Human SIgA2 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Bonner, A., Almogren, A., Furtado, P.B., Kerr, M.A., Perkins, S.J. | NOT | SOLUTION SCATTERING | null | null | false | false | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
4r4f | H | L | 0 | A | protein | null | hiv-1 env gp120 | VIRAL PROTEIN/IMMUNE SYSTEM/INHIBITOR | 08/19/14 | Crystal structure of non-neutralizing, A32-like antibody 2.2c in complex with HIV-1 YU2 gp120 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Acharya, P., Kwong, P.D. | 3.514 | X-RAY DIFFRACTION | 0.295 | 0.251 | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
7lde | K | J | 0 | D | protein | null | glutamate receptor | MEMBRANE PROTEIN | 01/13/21 | native AMPA receptor | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Yu, J., Rao, P., Gouaux, E. | 3.9 | ELECTRON MICROSCOPY | null | null | false | true | IGHV2 | IGKV10 | Kappa | null | null | null | null | null |
7jv6 | C | D | 0 | B | protein | null | sars-cov-2 spike glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 08/20/20 | SARS-CoV-2 spike in complex with the S2H13 neutralizing antibody (closed conformation) | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Park, Y.J., Tortorici, M.A., Walls, A.C., Czudnochowski, N., Seattle Structural Genomics Center for Infectious Disease (SSGCID), Snell, G., Veesler, D. | 3 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGLV7 | Lambda | null | null | null | null | null |
4qy8 | A | B | 0 | Q | peptide | null | merozoite surface antigen 2 | IMMUNE SYSTEM | 07/24/14 | Crystal Structure of anti-MSP2 Fv fragment (mAb6D8) in complex with 3D7-MSP2 14-30 | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | plasmodium falciparum 3d7 | Morales, R.A.V., MacRaild, C.A., Seow, J., Bankala, K., Drinkwater, N., McGowan, S., Rouet, R., Christ, D., Anders, R.F., Norton, R.S. | 1.353 | X-RAY DIFFRACTION | 0.165 | 0.152 | false | true | IGHV14 | IGKV3 | Kappa | 0 | -9.814126 | Unknown | null | TBD |
4i1n | B | null | 0 | A | protein | null | dihydrofolate reductase | OXIDOREDUCTASE/IMMUNE SYSTEM | 11/21/12 | R104A-ca1697 nanobody binding to the binary DHFR.folate complex | LAMA GLAMA; ESCHERICHIA COLI | lama glama | null | escherichia coli | Oyen, D., Steyaert, J., Barlow, J.N. | 1.888 | X-RAY DIFFRACTION | 0.214 | 0.177 | false | true | IGHV1 | null | null | null | null | null | null | null |
6qb4 | X | x | 0 | A | protein | null | induced myeloid leukemia cell differentiation protein mcl-1 | APOPTOSIS | 12/20/18 | Mcl1-scFv complex with an indole acid inhibitor | HOMO SAPIENS | homo sapiens | null | homo sapiens | Hargreaves, D. | 2.38 | X-RAY DIFFRACTION | 0.231 | 0.197 | true | true | unknown | unknown | unknown | null | null | null | null | null |
4tnw | U | h | 0 | Q | protein | null | avermectin-sensitive glutamate-gated chloride channel gluclalpha | TRANSPORT PROTEIN/IMMUNE SYSTEM | 06/05/14 | C. elegans glutamate-gated chloride channel (GluCl) in complex with Fab and POPC in a lipid-modulated conformation | CAENORHABDITIS ELEGANS; MUS MUSCULUS | mus musculus | mus musculus | caenorhabditis elegans | Althoff, T., Hibbs, R.E., Banerjee, S., Gouaux, E. | 3.2 | X-RAY DIFFRACTION | 0.251 | 0.227 | false | false | unknown | unknown | unknown | null | null | null | null | null |
7ly3 | D | C | 0 | A | protein | null | spike protein s1 | VIRAL PROTEIN/IMMUNE SYSTEM | 03/05/21 | Crystal structure of SARS-CoV-2 S NTD bound to S2M28 Fab | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | McCallum, M., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 3.0 | X-RAY DIFFRACTION | 0.234 | 0.209 | false | true | IGHV3 | IGLV3 | Lambda | null | null | null | null | null |
7k9j | J | N | 0 | C | protein | null | spike glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 09/29/20 | SARS-CoV-2 Spike in complex with neutralizing Fab 2H04 (three down conformation) | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; MUS MUSCULUS | mus musculus | mus musculus | severe acute respiratory syndrome coronavirus2 | Errico, J.M., Fremont, D.H., Center for Structural Genomics of Infectious Diseases (CSGID) | 3 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV5 | Kappa | null | null | null | null | null |
2dwd | A | B | 0 | C | protein | null | voltage-gated potassium channel | MEMBRANE PROTEIN | 08/10/06 | crystal structure of KcsA-FAB-TBA complex in Tl+ | STREPTOMYCES LIVIDANS; MUS MUSCULUS | mus musculus | mus musculus | streptomyces lividans | Yohannan, S., Zhou, Y. | 2.6 | X-RAY DIFFRACTION | 0.263 | 0.219 | false | false | IGHV1 | IGKV5 | Kappa | null | null | null | null | null |
7te8 | B | null | 0 | D | Hapten | P0T | cannabidiol | BIOSYNTHETIC PROTEIN | 01/04/22 | CA14-CBD-DB21 ternary complex | ARTIFICIAL SEQUENCES | artificial sequences | null | artificial sequences | Cao, S., Zheng, N. | 1.998 | X-RAY DIFFRACTION | 0.211 | 0.180 | false | true | IGHV3 | null | null | null | null | null | null | null |
6qd6 | A | null | 0 | null | null | null | null | STRUCTURAL PROTEIN | 12/31/18 | Molecular scaffolds expand the nanobody toolkit for cryo-EM applications: crystal structure of Mb-cHopQ-Nb207 | HELICOBACTER PYLORI; HELICOBACTER PYLORI (STRAIN G27) | helicobacter pylori, helicobacter pylori(strain g27) | null | null | Uchanski, T., Masiulis, S., Fischer, B., Kalichuk, V., Wohlkonig, A., Zogg, T., Remaut, H., Vranken, W., Aricescu, A.R., Pardon, E., Steyaert, J. | 2.84 | X-RAY DIFFRACTION | 0.239 | 0.204 | false | true | IGHV1 | null | null | null | null | null | null | null |
6crq | D | E | 0 | A | protein | null | envelope glycoprotein gp160 | VIRAL PROTEIN | 03/19/18 | Glutaraldehyde-treated BG505 SOSIP.664 Env in complex with PGV04 Fab | HUMAN IMMUNODEFICIENCY VIRUS 1 | human immunodeficiency virus 1 | human immunodeficiency virus 1 | human immunodeficiency virus 1 | Pallesen, J., Ward, A.B. | 4.2 | ELECTRON MICROSCOPY | null | null | false | true | unknown | unknown | unknown | null | null | null | null | null |
4hem | G | null | 0 | A | protein | null | bpp | VIRAL PROTEIN | 10/04/12 | Llama vHH-02 binder of ORF49 (RBP) from lactococcal phage TP901-1 | LACTOCOCCUS PHAGE TP901-1; LAMA GLAMA | lama glama | null | lactococcus phage tp901-1 | Desmyter, A., Spinelli, S., Farenc, C., Blangy, S., Bebeacua, C., van Sinderen, D., Mahony, J., Cambillau, C. | 1.65 | X-RAY DIFFRACTION | 0.177 | 0.167 | false | true | IGHV1 | null | null | null | null | null | null | null |
3qpx | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 02/14/11 | Crystal structure of Fab C2507 | HOMO SAPIENS, RATTUS NORVEGICUS | homo sapiens, rattus norvegicus | homo sapiens, rattus norvegicus | null | Luo, J., Teplyakov, A., Obmolova, O., Malia, T., Gilliland, G.L. | 2.0 | X-RAY DIFFRACTION | 0.264 | 0.225 | false | true | IGHV5 | IGKV22 | Kappa | null | null | null | null | null |
6w0a | A | B | 0 | C | protein | null | ph-gated potassium channel kcsa | MEMBRANE PROTEIN | 02/29/20 | Open-gate KcsA soaked in 1 mM BaCl2 | RATTUS NORVEGICUS; STREPTOMYCES LIVIDANS | rattus norvegicus | rattus norvegicus | streptomyces lividans | Rohaim, A., Gong, L., Li, J. | 3.237 | X-RAY DIFFRACTION | 0.242 | 0.180 | false | true | IGHV1 | IGKV5 | Kappa | null | null | null | null | null |
2kqm | null | A | 13 | null | null | null | null | IMMUNE SYSTEM | 11/11/09 | Solution structure of the KI O18/O8 Y87H immunoglobulin light chain variable domain | HOMO SAPIENS | null | homo sapiens | null | Volkman, B.F., Peterson, F.C., Ramirez-Alvarado, M., Baden, E.M. | NOT | SOLUTION NMR | null | null | false | true | null | IGKV1 | Kappa | null | null | null | null | null |
1e4w | H | L | 0 | P | peptide | null | cyclic peptide | IMMUNE SYSTEM | 07/12/00 | crossreactive binding of a circularized peptide to an anti-TGFalpha antibody Fab-fragment | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | null | Hahn, M., Winkler, D., Misselwitz, R., Wessner, H., Welfle, K., Zahn, G., Schneider-Mergener, J., Hoehne, W. | 1.95 | X-RAY DIFFRACTION | 0.269 | 0.204 | false | false | IGHV1 | IGKV10 | Kappa | null | null | null | null | null |
6nfn | P | O | 0 | O | Hapten | BCG | 3-(BENZOYLOXY)-8-METHYL-8-AZABICYCLO[3.2.1]OCTANE-2-CARBOXYLIC ACID | IMMUNE SYSTEM | 12/20/18 | Fab fragement of anti-cocaine antibody h2E2 bound to benzoylecgonine | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Pokkuluri, P.R., Tan, K. | 2.63 | X-RAY DIFFRACTION | 0.244 | 0.185 | false | true | IGHV3 | IGLV2 | Lambda | null | null | null | null | null |
7qn6 | K | null | 0 | B | protein | null | gamma-aminobutyric acid receptor subunit beta-3 | MEMBRANE PROTEIN | 12/20/21 | Cryo-EM structure of human full-length beta3delta GABA(A)R in complex with nanobody Nb25 | HOMO SAPIENS; LAMA GLAMA | lama glama | null | homo sapiens | Sente, A., Desai, R., Naydenova, K., Malinauskas, T., Jounaidi, Y., Miehling, J., Zhou, X., Masiulis, S., Hardwick, S.W., Chirgadze, D.Y., Miller, K.W., Aricescu, A.R. | 2.9 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
7msq | H | L | 0 | A | protein | null | spike protein s1 | VIRAL PROTEIN/ANTIVIRAL PROTEIN | 05/12/21 | Complex between the Fab arm of AB-3467 and the SARS-CoV-2 receptor binding domain (RBD) | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Langley, D.B., Christ, D. | 2.29 | X-RAY DIFFRACTION | 0.245 | 0.194 | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
2mcg | null | 2 | 0 | null | null | null | null | IMMUNOGLOBULIN | 05/09/89 | THREE-DIMENSIONAL STRUCTURE OF A LIGHT CHAIN DIMER CRYSTALLIZED IN WATER. CONFORMATIONAL FLEXIBILITY OF A MOLECULE IN TWO CRYSTAL FORMS | HOMO SAPIENS | null | homo sapiens | null | Ely, K.R., Herron, J.N., Edmundson, A.B. | 2.0 | X-RAY DIFFRACTION | unknown | unknown | false | true | null | IGLV2 | Lambda | null | null | null | null | null |
6mn7 | I | i | 0 | C | protein | null | envelope glycoprotein gp120 | VIRAL PROTEIN | 10/01/18 | Cryo-EM structure of BG505.SOSIP.664 in complex with BF520.1 antigen binding fragment | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | null | human immunodeficiency virus 1 | Williams, J.A., Lee, K.K., Overbaugh, J. | 4.8 | ELECTRON MICROSCOPY | null | null | true | true | unknown | unknown | unknown | null | null | null | null | null |
4yhp | C | D | 0 | Q | peptide | null | h3k9me3 peptide | IMMUNE SYSTEM | 02/27/15 | Crystal structure of 309M3-B Fab in complex with H3K9me3 peptide | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | synthetic construct | Hattori, T., Dementieva, I.S., Montano, S.P., Koide, S. | 2.53 | X-RAY DIFFRACTION | 0.250 | 0.211 | false | true | IGHV3 | IGLV3 | Lambda | 0 | -11.867518 | Unknown | null | TBD |
6phf | C | D | 0 | E | protein | null | 25 kda ookinete surface antigen | IMMUNE SYSTEM | 06/25/19 | Pfs25 in complex with the human transmission blocking antibody 2587 | HOMO SAPIENS; PLASMODIUM FALCIPARUM | homo sapiens | homo sapiens | plasmodium falciparum | McLeod, B.R., Julien, J.P. | 3.1 | X-RAY DIFFRACTION | 0.267 | 0.237 | false | true | IGHV1 | IGLV3 | Lambda | null | null | null | null | null |
4krm | L | null | 0 | K | protein | null | epidermal growth factor receptor | TRANSFERASE/IMMUNE SYSTEM | 05/16/13 | Nanobody/VHH domain 7D12 in complex with domain III of the extracellular region of EGFR, pH 3.5 | LAMA GLAMA; HOMO SAPIENS | lama glama | null | homo sapiens | Ferguson, K.M., Schmitz, K.R. | 2.655 | X-RAY DIFFRACTION | 0.244 | 0.208 | false | true | IGHV1 | null | null | null | null | null | null | null |
5c7x | M | N | 0 | B | protein | null | granulocyte-macrophage colony-stimulating factor | IMMUNE SYSTEM | 06/25/15 | Crystal structure of MOR04357, a neutralizing anti-human GM-CSF antibody Fab fragment in complex with human GM-CSF | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Eylenstein, R., Weinfurtner, D., Steidl, S., Boettcher, J., Augustin, M. | 2.95 | X-RAY DIFFRACTION | 0.276 | 0.234 | false | true | IGHV3 | IGLV3 | Lambda | 0 | -16.913816 | Unknown | null | TBD |
2w65 | A | B | 0 | E | peptide | null | collagen derived peptide pcii-cit1 | IMMUNE SYSTEM | 12/17/08 | Anti citrullinated Collagen type 2 antibody acc4 in complex with a citrullinated peptide | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | mus musculus | Uysal, H., Bockermann, R., Nandakumar, K.S., Sehnert, B., Bajtner, E., Engstrom, A., Serre, G., Burkhardt, H., Thunnissen, M.M.G.M., Holmdahl, R. | 2.21 | X-RAY DIFFRACTION | 0.285 | 0.234 | false | false | IGHV9 | IGKV1 | Kappa | null | null | null | null | null |
7o33 | H | L | 0 | P | peptide | null | apsa epitope peptide | IMMUNE SYSTEM | 04/01/21 | Crystal structure of the anti-PAS Fab 3.1 in complex with its epitope peptide | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | synthetic construct | Schilz, J., Skerra, A. | 1.85 | X-RAY DIFFRACTION | 0.248 | 0.209 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
7so7 | X | Y | 0 | B | protein | null | toxin b | TOXIN/IMMUNE SYSTEM | 10/29/21 | Novel structural insights for a pair of monoclonal antibodies recognizing non-overlapping epitopes of the glucosyltransferase domain of Clostridium difficile toxin B | CLOSTRIDIOIDES DIFFICILE; HOMO SAPIENS | homo sapiens | homo sapiens | clostridioides difficile | Liu, J. | 3.59 | X-RAY DIFFRACTION | 0.258 | 0.209 | false | true | IGHV3 | IGLV5 | Lambda | null | null | null | null | null |
7k61 | N | n | 0 | G | F | H | protein | protein | protein | NA | NA | NA | histone h2a type 1-b/e | histone h4 | histone h2b type 1-j | NUCLEAR PROTEIN/DNA | 09/17/20 | Cryo-EM structure of 197bp nucleosome aided by scFv | HOMO SAPIENS; MUS MUSCULUS | mus musculus | null | homo sapiens | homo sapiens | homo sapiens | Zhou, B.-R., Bai, Y. | 2.85 | ELECTRON MICROSCOPY | null | null | true | true | unknown | unknown | unknown | null | null | null | null | null |
7ly0 | H | L | 0 | A | protein | null | spike glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 03/05/21 | SARS-CoV-2 S/S2M11/S2M28 Local Refinement | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | McCallum, M., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 2.6 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGLV3 | Lambda | null | null | null | null | null |
1yc7 | A | null | 0 | null | null | null | null | IMMUNE SYSTEM | 12/22/04 | cAbAn33 VHH fragment against VSG | CAMELUS DROMEDARIUS | camelus dromedarius | null | null | Conrath, K., Vincke, C., Stijlemans, B., Schymkowitz, J., Wyns, L., Muyldermans, S., Loris, R. | 1.6 | X-RAY DIFFRACTION | 0.212 | 0.192 | false | true | IGHV1 | null | null | null | null | null | null | null |
6qfc | B | b | 0 | A | protein | null | induced myeloid leukemia cell differentiation protein mcl-1 | APOPTOSIS | 01/09/19 | Structure of an anti-Mcl1 scFv | HOMO SAPIENS | homo sapiens | null | homo sapiens | Luptak, J. | 1.96 | X-RAY DIFFRACTION | 0.219 | 0.193 | true | true | unknown | unknown | unknown | null | null | null | null | null |
6e8v | E | F | 0 | null | null | null | null | IMMUNE SYSTEM | 09/04/19 | The crystal structure of bovine ultralong antibody BOV-1 | BOS TAURUS | bos taurus | bos taurus | null | Dong, J., Crowe, J.E. | 3.79 | X-RAY DIFFRACTION | 0.275 | 0.218 | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
4rgo | H | L | 0 | S | protein | null | enterotoxin type b | TOXIN/IMMUNE SYSTEM | 09/30/14 | Structure of Staphylococcal Enterotoxin B bound to the neutralizing antibody 14G8 | STAPHYLOCOCCUS AUREUS; MUS MUSCULUS | mus musculus | mus musculus | staphylococcus aureus | Franklin, M.C., Dutta, K., Varshney, A.K., Goger, M.J., Fries, B.C. | 1.8 | X-RAY DIFFRACTION | 0.189 | 0.142 | false | false | IGHV5 | IGKV5 | Kappa | 0 | -11.053614 | BLI | null | TBD |
7qnc | F | null | 0 | C | protein | null | gamma-aminobutyric acid receptor subunit beta-3 | MEMBRANE PROTEIN | 12/20/21 | Cryo-EM structure of human full-length extrasynaptic alpha4beta3delta GABA(A)R in complex with THIP (gaboxadol), histamine and nanobody Nb25 | HOMO SAPIENS; LAMA GLAMA | lama glama | null | homo sapiens | Sente, A., Desai, R., Naydenova, K., Malinauskas, T., Jounaidi, Y., Miehling, J., Zhou, X., Masiulis, S., Hardwick, S.W., Chirgadze, D.Y., Miller, K.W., Aricescu, A.R. | 2.9 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
5do2 | C | D | 0 | B | protein | null | s protein | VIRAL PROTEIN/IMMUNE SYSTEM | 09/10/15 | Complex structure of MERS-RBD bound with 4C2 antibody | MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS; MUS MUSCULUS | mus musculus | mus musculus | middle east respiratory syndrome coronavirus | Li, Y., Wan, Y., Liu, P., Zhao, J., Lu, G., Qi, J., Wang, Q., Lu, X., Wu, Y., Liu, W., Yuen, K.Y., Perlman, S., Gao, G.F., Yan, J. | 2.409 | X-RAY DIFFRACTION | 0.289 | 0.245 | false | false | IGHV5 | IGKV10 | Kappa | 0 | -9.263879 | SPR | null | TBD |
7nd3 | H | L | 0 | B | protein | null | spike glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 01/30/21 | EM structure of SARS-CoV-2 Spike glycoprotein in complex with COVOX-40 Fab | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Duyvesteyn, H.M.E., Zhao, Y., Ren, J., Stuart, D. | 3.7 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6uyd | A | B | 0 | F | protein | null | envelope glycoprotein e2 | VIRAL PROTEIN/IMMUNE SYSTEM | 11/13/19 | Structure of Hepatitis C Virus Envelope Glycoprotein E2mc3-v1 redesigned core from genotype 1a bound to broadly neutralizing antibody AR3C | HEPATITIS C VIRUS (ISOLATE H); HOMO SAPIENS | homo sapiens | homo sapiens | hepatitis c virus (isolate h) | Tzarum, N., Wilson, I.A., Zhu, J. | 1.897 | X-RAY DIFFRACTION | 0.243 | 0.208 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
5a3i | C | D | 0 | A | protein | null | hemagglutinin | VIRAL PROTEIN | 06/01/15 | Crystal Structure of a Complex formed between FLD194 Fab and Transmissible Mutant H5 Haemagglutinin | INFLUENZA A VIRUS (A/VIETNAM/1203/2004(H5N1)); HOMO SAPIENS | homo sapiens | homo sapiens | influenza a virus (a/vietnam/1203/2004(h5n1)) | Xiong, X., Corti, D., Liu, J., Pinna, D., Foglierini, M., Calder, L.J., Martin, S.R., Lin, Y.P., Walker, P.A., Collins, P.J., Monne, I., Suguitan Jr, A.L., Santos, C., Temperton, N.J., Subbarao, K., Lanzavecchia, A., Gamblin, S.J., Skehel, J.J. | 2.89 | X-RAY DIFFRACTION | 0.277 | 0.244 | false | false | IGHV5 | IGKV2 | Kappa | null | null | null | null | null |
6w09 | J | N | 0 | F | protein | null | e2 glycoprotein | VIRUS/IMMUNE SYSTEM | 02/29/20 | Human mAbs broadly protect against infection of arthritiogenic alphaviruses by recognizing conserved elements of the MXR8 receptor binding domain | CHIKUNGUNYA VIRUS; HOMO SAPIENS | homo sapiens | homo sapiens | chikungunya virus | Miller, A.S., Kuhn, R.J. | 5.3 | ELECTRON MICROSCOPY | null | null | false | true | IGHV9 | IGLV1 | Lambda | null | null | null | null | null |
7jvd | H | L | 0 | A | carbohydrate | BDP | BETA-D-GLUCOPYRANURONIC ACID | IMMUNE SYSTEM | 08/20/20 | Fab of 5.6 monoclonal mouse IgG1 co-crystallized with the trisaccharide form of serotype 3 pneumococcal capsular polysaccharide | MUS MUSCULUS | mus musculus | mus musculus | null | Ozdilek, A., Huang, J., Paschall, A.V., Babb, R., Middleton, D.R., Duke, J.A., Pirofski, L., Mousa, J.J., Avci, F.Y. | 2.3 | X-RAY DIFFRACTION | 0.221 | 0.183 | false | true | IGHV5 | IGKV4 | Kappa | null | null | null | null | null |
7kzb | H | L | 0 | C | protein | null | spike glycoprotein | VIRAL PROTEIN/Immune System | 12/10/20 | Potent SARS-CoV-2 binding and neutralization through maturation of iconic SARS-CoV-1antibodies | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Langley, D.B., Christ, D. | 2.83 | X-RAY DIFFRACTION | 0.336 | 0.251 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
4hep | G | null | 0 | A | protein | null | bpp | VIRAL PROTEIN | 10/04/12 | Complex of lactococcal phage TP901-1 with a llama vHH (vHH17) binder (nanobody) | LACTOCOCCUS PHAGE TP901-1; LAMA GLAMA | lama glama | null | lactococcus phage tp901-1 | Desmyter, A., Spinelli, S., Farenc, C., Blangy, S., Bebeacua, C., van Sinderen, D., Mahony, J., Cambillau, C. | 1.75 | X-RAY DIFFRACTION | 0.204 | 0.198 | false | true | IGHV1 | null | null | null | null | null | null | null |
4n90 | F | G | 0 | S | B | protein | protein | NA | NA | tumor necrosis factor receptor superfamily member 10b | tumor necrosis factor ligand superfamily member 10 | Apoptosis/Immune System | 10/18/13 | Crystal structure of ternary complex of TRAIL, DR5, and Fab fragment from a DR5 agonist antibody | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | homo sapiens | Huang, X. | 3.3 | X-RAY DIFFRACTION | 0.286 | 0.229 | false | true | IGHV4 | IGKV3 | Kappa | null | null | null | null | null |
7kyo | H | L | 0 | B | protein | null | manganese abc transporter, atp-binding protein | TRANSPORT PROTEIN/IMMUNE SYSTEM | 12/08/20 | PsaBC from Streptococcus pneumoniae in complex with Fab | STREPTOCOCCUS PNEUMONIAE SEROTYPE 2 (STRAIN D39 / NCTC 7466); MUS MUSCULUS | mus musculus | mus musculus | streptococcus pneumoniae serotype 2 (strain d39/ nctc 7466) | Maher, M.J., Sjohamn, J. | 2.85 | X-RAY DIFFRACTION | 0.271 | 0.238 | false | true | IGHV5 | IGKV3 | Kappa | null | null | null | null | null |
6lbh | C | D | 0 | B | protein | null | magnesium transporter mgte | TRANSPORT PROTEIN/IMMUNE SYSTEM | 11/14/19 | Cryo-EM structure of the MgtE Mg2+ channel under Mg2+-free conditions | THERMUS THERMOPHILUS HB8; MUS MUSCULUS | mus musculus | mus musculus | thermus thermophilus hb8 | Hattori, M., Jin, F. | 3.7 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
1bvk | E | D | 0 | F | protein | null | lysozyme | COMPLEX (HUMANIZED ANTIBODY/HYDROLASE) | 09/16/98 | HUMANIZED ANTI-LYSOZYME FV COMPLEXED WITH LYSOZYME | HOMO SAPIENS; GALLUS GALLUS | homo sapiens | homo sapiens | gallus gallus | Holmes, M.A., Buss, T.N., Foote, J. | 2.7 | X-RAY DIFFRACTION | 0.297 | 0.208 | false | true | IGHV4 | IGKV1 | Kappa | 0 | -10.53 | Other | 20 | 1560463 |
5xqy | null | F | 0 | null | null | null | null | IMMUNE SYSTEM | 06/07/17 | Structure of monomeric mutant of REI immunoglobulin light chain variable domain crystallized at pH 8 | HOMO SAPIENS | null | homo sapiens | null | Mine, S., Nakamura, T., Uegaki, K., Hamada, D. | 2.9 | X-RAY DIFFRACTION | 0.285 | 0.231 | false | true | null | IGKV1 | Kappa | null | null | null | null | null |
6e8v | J | K | 0 | null | null | null | null | IMMUNE SYSTEM | 09/04/19 | The crystal structure of bovine ultralong antibody BOV-1 | BOS TAURUS | bos taurus | bos taurus | null | Dong, J., Crowe, J.E. | 3.79 | X-RAY DIFFRACTION | 0.275 | 0.218 | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
7c88 | H | L | 0 | M | protein | null | programmed cell death 1 ligand 1 | IMMUNE SYSTEM | 05/29/20 | Complex structure of JS003 and PD-L1 | MUS MUSCULUS; HOMO SAPIENS | mus musculus | mus musculus | homo sapiens | Bi, X., Shi, R., Chai, Y., Qi, J., Yan, J., Tan, S. | 1.997 | X-RAY DIFFRACTION | 0.258 | 0.222 | false | true | IGHV4 | IGKV4 | Kappa | null | null | null | null | null |
1a8j | null | L | 0 | L | Hapten | PME | N-L-ALPHA-ASPARTYL L-PHENYLALANINE 1-METHYL ESTER | IMMUNOGLOBULIN | 03/26/98 | IMMUNOGLOBULIN LAMBDA LIGHT CHAIN DIMER (MCG) COMPLEX WITH ASPARTAME | HOMO SAPIENS | null | homo sapiens | homo sapiens | Edmundson, A.B., Manion, C.V. | 2.7 | X-RAY DIFFRACTION | 0.380 | 0.220 | false | false | null | IGLV2 | Lambda | null | null | null | null | null |
7kbp | B | b | 0 | null | null | null | null | PROTEIN BINDING | 10/02/20 | Herceptin Diabody with R83T, E85C Mutations | HOMO SAPIENS | homo sapiens | null | null | Chesterman, C., Arnold, E. | 2.3 | X-RAY DIFFRACTION | 0.232 | 0.184 | true | true | unknown | unknown | unknown | null | null | null | null | null |
4pir | J | null | 0 | D | protein | null | 5-hydroxytryptamine receptor 3a | TRANSPORT PROTEIN | 05/09/14 | X-ray structure of the mouse serotonin 5-HT3 receptor | MUS MUSCULUS; LAMA GLAMA | lama glama | null | mus musculus | Hassaine, G., Deluz, C., Grasso, L., Wyss, R., Tol, M.B., Hovius, R., Graff, A., Stahlberg, H., Tomizaki, T., Desmyter, A., Moreau, C., Li, X.-D., Poitevin, F., Vogel, H., Nury, H. | 3.5 | X-RAY DIFFRACTION | 0.257 | 0.217 | false | true | IGHV1 | null | null | null | null | null | null | null |
2kqn | null | B | 10 | null | null | null | null | IMMUNE SYSTEM | 11/11/09 | Solution structure of the AL-09 H87Y immunoglobulin light chain variable domain | HOMO SAPIENS | null | homo sapiens | null | Volkman, B.F., Peterson, F.C., Ramirez-Alvarado, M., Baden, E.M. | NOT | SOLUTION NMR | null | null | false | true | null | IGKV1 | Kappa | null | null | null | null | null |
5gux | H | L | 0 | B | C | protein | protein | NA | NA | nitric oxide reductase subunit b | nitric oxide reductase subunit c | MEMBRANE PROTEIN | 08/31/16 | Cytochrome c-dependent nitric oxide reductase (cNOR) from Pseudomonas aeruginosa in complex with xenon | MUS MUSCULUS; PSEUDOMONAS AERUGINOSA PAO1 | pseudomonas aeruginosa pao1 | mus musculus | pseudomonas aeruginosa pao1 | pseudomonas aeruginosa pao1 | Ishii, S., Terasaka, E., Sugimoto, H., Shiro, Y., Tosha, T. | 3.3 | X-RAY DIFFRACTION | 0.268 | 0.209 | false | false | IGHV1 | IGKV16 | Kappa | null | null | null | null | null |
4unt | null | D | 0 | null | null | null | null | IMMUNE SYSTEM | 05/30/14 | Induced monomer of the Mcg variable domain | HOMO SAPIENS | null | homo sapiens | null | Brumshtein, B., Esswein, S.R., Landau, M., Ryan, C.M., Whitelegge, J.P., Phillips, M.L., Cascio, D., Sawaya, M.R., Eisenberg, D.S. | 2.7 | X-RAY DIFFRACTION | 0.28925 | 0.24328 | false | true | null | IGLV2 | Lambda | null | null | null | null | null |
6p9j | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 06/17/20 | crystal structure of human anti staphylococcus aureus antibody STAU-229 Fab | HOMO SAPIENS | homo sapiens | homo sapiens | null | Dong, J., Crowe, J.E. | 2.2 | X-RAY DIFFRACTION | 0.267 | 0.218 | false | true | IGHV1 | IGLV2 | Lambda | null | null | null | null | null |
6u02 | G | F | 0 | E | protein | null | neuraminidase | VIRAL PROTEIN/IMMUNE SYSTEM | 08/13/19 | CryoEM-derived model of NA-63 Fab in complex with N9 Shanghai2 | INFLUENZA A VIRUS (A/ENVIRONMENT/SHANGHAI/S1439/2013(H7N9)); HOMO SAPIENS | homo sapiens | homo sapiens | influenza a virus(a/environment/shanghai/s1439/2013(h7n9)) | Ward, A.B., Turner, H.L., Zhu, X. | 3.05 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6woq | G | H | 0 | F | protein | null | envelope glycoprotein e2 | IMMUNE SYSTEM/Viral Protein | 04/25/20 | Structure of Hepatitis C Virus Envelope Glycoprotein E2 core from genotype 1a bound to neutralizing antibody HC1AM and non neutralizing antibody E1 | HOMO SAPIENS; HEPATITIS C VIRUS (ISOLATE H) | homo sapiens | homo sapiens | hepatitis c virus (isolate h) | Tzarum, N., Wilson, I.A., Law, M. | 3.667 | X-RAY DIFFRACTION | 0.277 | 0.227 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
1rzi | J | I | 0 | null | null | null | null | IMMUNE SYSTEM | 12/24/03 | Crystal structure of human anti-HIV-1 gp120-reactive antibody 47e fab | HOMO SAPIENS | homo sapiens | homo sapiens | null | Huang, C.C., Venturi, M., Majeed, S., Moore, M.J., Phogat, S., Zhang, M.-Y., Dimitrov, D.S., Hendrickson, W.A., Robinson, J., Sodroski, J., Wyatt, R., Choe, H., Farzan, M., Kwong, P.D. | 2.9 | X-RAY DIFFRACTION | 0.321 | 0.233 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
6m87 | L | K | 0 | K | Hapten | 2M9 | 8-methoxypyrene-1,3,6-trisulfonic acid | IMMUNE SYSTEM | 08/21/18 | Fab 10A6 in complex with MPTS | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Stanfield, R.L., Wilson, I.A. | 2.609 | X-RAY DIFFRACTION | 0.265 | 0.228 | false | false | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
2aj3 | D | C | 0 | null | null | null | null | IMMUNE SYSTEM | 08/01/05 | Crystal Structure of a Cross-Reactive HIV-1 Neutralizing CD4-Binding Site Antibody Fab m18 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Prabakaran, P., Gan, J., Wu, Y.Q., Zhang, M.Y., Dimitrov, D.S., Ji, X. | 2.03 | X-RAY DIFFRACTION | 0.269 | 0.225 | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
4jdt | H | L | 0 | G | protein | null | gp120 | viral protein/immune system | 02/25/13 | Crystal structure of chimeric germ-line precursor of NIH45-46 Fab in complex with gp120 of 93TH057 HIV-1 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Scharf, L., Diskin, R., Bjorkman, P.J. | 3.26 | X-RAY DIFFRACTION | 0.267 | 0.227 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
5jop | H | L | 0 | B | carbohydrate | NAG | N-ACETYL-D-GLUCOSAMINE | IMMUNE SYSTEM | 05/02/16 | Crystal structure of anti-glycan antibody Fab14.22 in complex with Streptococcus pneumoniae serotype 14 tetrasaccharide at 1.75 A | MUS MUSCULUS | mus musculus | mus musculus | null | Sarkar, A., Irimia, A., Teyton, L., Wilson, I.A. | 1.75 | X-RAY DIFFRACTION | 0.200 | 0.165 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
6a3w | D | E | 0 | F | protein | null | tumor necrosis factor receptor superfamily member 9 | IMMUNE SYSTEM | 06/17/18 | Complex structure of 4-1BB and utomilumab | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Li, Y., Tan, S., Zhang, C., Chai, Y., Qi, J., Tien, P., Gao, S., Gao, G.F. | 2.0 | X-RAY DIFFRACTION | 0.215 | 0.185 | false | true | IGHV5 | IGLV3 | Lambda | null | null | null | null | null |
2xa8 | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 03/30/10 | Crystal structure of the Fab domain of omalizumab at 2.41A | HOMO SAPIENS | homo sapiens | homo sapiens | null | Huang, C.H., Hung, F.H.A., Lim, C., Chang, T.W., Ma, C. | 2.42 | X-RAY DIFFRACTION | 0.269 | 0.221 | false | false | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
25c8 | H | L | 0 | L | Hapten | GEP | N-METHYL-N-(PARA-GLUTARAMIDOPHENYL-ETHYL)-PIPERIDINIUM ION | CATALYTIC ANTIBODY | 03/18/98 | CATALYTIC ANTIBODY 5C8, FAB-HAPTEN COMPLEX | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Gruber, K., Wilson, I.A. | 2.0 | X-RAY DIFFRACTION | 0.292 | 0.229 | false | false | IGHV14 | IGKV4 | Kappa | null | null | null | null | null |
1q1j | I | M | 0 | Q | peptide | null | gp120 v3 peptide | IMMUNE SYSTEM | 07/21/03 | Crystal Structure Analysis of anti-HIV-1 Fab 447-52D in complex with V3 peptide | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | null | Stanfield, R.L., Gorny, M.K., Williams, C., Zolla-Pazner, S., Wilson, I.A. | 2.5 | X-RAY DIFFRACTION | 0.285 | 0.250 | false | false | IGHV3 | IGLV1 | Lambda | null | null | null | null | null |
5w9h | E | F | 0 | D | protein | null | mers s | VIRAL PROTEIN | 06/23/17 | MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4 | MIDDLE EAST RESPIRATORY SYNDROME-RELATED CORONAVIRUS; MUS MUSCULUS | mus musculus | mus musculus | middle east respiratory syndrome-relatedcoronavirus | Pallesen, J., Ward, A.B. | 4 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
7l06 | D | F | 0 | W | carbohydrate | MAN | ALPHA-D-MANNOSE | VIRAL PROTEIN/IMMUNE SYSTEM | 12/11/20 | Cryo-EM structure of SARS-CoV-2 2P S ectodomain bound to two copies of domain-swapped antibody 2G12 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | null | Manne, K., Henderson, R., Acharya, P. | 3.3 | ELECTRON MICROSCOPY | null | null | false | true | unknown | IGKV1 | Kappa | null | null | null | null | null |
4jdv | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 02/25/13 | Crystal structure of germ-line precursor of NIH45-46 Fab | HOMO SAPIENS | homo sapiens | homo sapiens | null | Diskin, R., Scharf, L., Bjorkman, P.J. | 1.65 | X-RAY DIFFRACTION | 0.203 | 0.174 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
4jo4 | I | M | 0 | null | null | null | null | IMMUNE SYSTEM | 03/16/13 | Crystal structure of rabbit mAb R20 Fab | ORYCTOLAGUS CUNICULUS | oryctolagus cuniculus | oryctolagus cuniculus | null | Pan, R.M., Kong, X.P. | 2.27 | X-RAY DIFFRACTION | 0.226 | 0.184 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
4lri | C | B | 0 | null | null | null | null | Immune System | 07/19/13 | Anti CMV Fab Fragment | HOMO SAPIENS | homo sapiens | homo sapiens | null | Stengel, K.F. | 1.65 | X-RAY DIFFRACTION | 0.212 | 0.187 | false | true | IGHV3 | IGKV2 | Kappa | null | null | null | null | null |
5lbs | I | M | 0 | B | protein | null | envelope protein e | IMMUNE SYSTEM-VIRAL PROTEIN | 06/17/16 | structural basis of Zika and Dengue virus potent antibody cross-neutralization | ZIKA VIRUS; HOMO SAPIENS | homo sapiens | homo sapiens | zika virus | VANEY, M.C., ROUVINSKI, A., BARBA-SPAETH, G., REY, F.A. | 2.41 | X-RAY DIFFRACTION | 0.217 | 0.194 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
7vne | V | null | 0 | C | B | protein | protein | NA | NA | spike glycoprotein | spike glycoprotein | VIRAL PROTEIN | 10/10/21 | Structure of the SARS-CoV-2 spike glycoprotein in complex with a human single domain antibody n3113.1 (UUU-state) | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | null | severe acute respiratory syndrome coronavirus2 | severe acute respiratory syndrome coronavirus2 | Yang, Z., Wang, Y., Kong, Y., Jin, Y., Wu, Y., Ying, T. | 3.5 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | null | null | null | null | null | null | null |
2kh2 | B | b | 6 | A | protein | null | interleukin-1 beta | Cytokine/IMMUNE SYSTEM | 03/23/09 | Solution structure of a scFv-IL-1B complex | HOMO SAPIENS; MUS MUSCULUS | mus musculus | null | homo sapiens | Wilkinson, I.C., Hall, C.J., Veverka, V., Muskett, F.W., Stephens, P.E., Taylor, R.J., Henry, A.J., Carr, M.D. | NOT | SOLUTION NMR | null | null | true | true | unknown | unknown | unknown | null | null | null | null | null |
5bvj | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 06/05/15 | The molecular mode of action and species specificity of canakinumab, a human monoclonal antibody neutralizing IL-1beta | HOMO SAPIENS | homo sapiens | homo sapiens | null | Rondeau, J.M. | 2.0 | X-RAY DIFFRACTION | 0.228 | 0.186 | false | true | IGHV3 | IGKV6 | Kappa | null | null | null | null | null |
6al5 | H | L | 0 | A | protein | null | b-lymphocyte antigen cd19 | IMMUNE SYSTEM | 08/07/17 | COMPLEX BETWEEN CD19 (N138Q MUTANT) AND B43 FAB | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Teplyakov, A., Obmolova, G., Gilliland, G.L. | 3.0 | X-RAY DIFFRACTION | 0.263 | 0.189 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
5vj6 | O | P | 0 | A | D | protein | protein | NA | NA | envelope glycoprotein gp160 | envelope glycoprotein gp160 | VIRAL PROTEIN/IMMUNE SYSTEM | 04/18/17 | BG505 SOSIP.664 in complex with broadly neutralizing antibodies PG9 and 8ANC195 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | human immunodeficiency virus 1 | Wang, H., Bjorkman, P.J. | 11.5 | ELECTRON MICROSCOPY | null | null | false | true | unknown | IGKV1 | Kappa | null | null | null | null | null |
5kjr | H | L | 0 | G | protein | null | clade a/e 93th057 hiv-1 gp120 core | VIRAL PROTEIN/IMMUNE SYSTEM/INHIBITOR | 06/20/16 | Crystal structure of the ADCC-potent antibody N60-i3 Fab in complex with HIV-1 Clade A/E gp120 W69A/S115W mutant and M48U1. | HOMO SAPIENS; HUMAN IMMUNODEFICIENCY VIRUS 1; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Tolbert, W.D., Pazgier, M. | 2.98 | X-RAY DIFFRACTION | 0.306 | 0.249 | false | true | IGHV4 | IGLV2 | Lambda | null | null | null | null | null |
2kh2 | B | b | 44 | A | protein | null | interleukin-1 beta | Cytokine/IMMUNE SYSTEM | 03/23/09 | Solution structure of a scFv-IL-1B complex | HOMO SAPIENS; MUS MUSCULUS | mus musculus | null | homo sapiens | Wilkinson, I.C., Hall, C.J., Veverka, V., Muskett, F.W., Stephens, P.E., Taylor, R.J., Henry, A.J., Carr, M.D. | NOT | SOLUTION NMR | null | null | true | true | unknown | unknown | unknown | null | null | null | null | null |
7tfn | H | L | 0 | A | protein | null | envelope glycoprotein bg505 sosip.664 - gp120 | VIRAL PROTEIN/IMMUNE SYSTEM | 01/06/22 | Cryo-EM structure of CD4bs antibody Ab1303 in complex with HIV-1 Env trimer BG505 SOSIP.664 | HUMAN IMMUNODEFICIENCY VIRUS 1; MACACA MULATTA | macaca mulatta | macaca mulatta | human immunodeficiency virus 1 | Yang, Z., Bjorkman, P.J. | 4.0 | ELECTRON MICROSCOPY | null | null | false | true | IGHV4 | IGLV4 | Lambda | null | null | null | null | null |
6ct7 | A | B | 0 | T | peptide | null | ace-met-asp-val-phe-met-lys-gly-leu-ser-lys | IMMUNE SYSTEM | 12/19/18 | Fab of anti-a-synuclein antibody BIIB054 in complex with acetylated a-synuclein peptide (1-10) | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | homo sapiens | Arndt, J.W. | 1.903 | X-RAY DIFFRACTION | 0.223 | 0.180 | false | true | IGHV3 | IGLV3 | Lambda | null | null | null | null | null |
7czv | I | M | 0 | B | protein | null | spike glycoprotein | VIRAL PROTEIN | 09/09/20 | S protein of SARS-CoV-2 in complex bound with P5A-1B6_3B | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Yan, R.H., Zhang, Y.Y., Li, Y.N., Zhou, Q. | 3.3 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6uig | H | L | 0 | G | protein | null | hemagglutinin | ANTIVIRAL PROTEIN | 09/30/19 | Crystal structure of human monoclonal antibody H7.200 in complex with H7N9 hemagglutinin HA1 | INFLUENZA A VIRUS; HOMO SAPIENS | homo sapiens | homo sapiens | influenza a virus | Dong, J., Crowe, J.E. | 3.2 | X-RAY DIFFRACTION | 0.234 | 0.207 | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
4gw1 | B | A | 0 | null | null | null | null | Immune system | 08/31/12 | cQFD Meditope | MURINAE,HOMO SAPIENS; SYNTHETIC CONSTRUCT | murinae,homo sapiens | murinae,homo sapiens | null | Donaldson, J.M., Zer, C., Avery, K.N., Bzymek, K.P., Horne, D.A., Williams, J.C. | 2.24 | X-RAY DIFFRACTION | 0.226 | 0.182 | false | true | IGHV2 | IGKV5 | Kappa | 0 | -8.685503 | Unknown | null | TBD |
2kh2 | B | b | 45 | A | protein | null | interleukin-1 beta | Cytokine/IMMUNE SYSTEM | 03/23/09 | Solution structure of a scFv-IL-1B complex | HOMO SAPIENS; MUS MUSCULUS | mus musculus | null | homo sapiens | Wilkinson, I.C., Hall, C.J., Veverka, V., Muskett, F.W., Stephens, P.E., Taylor, R.J., Henry, A.J., Carr, M.D. | NOT | SOLUTION NMR | null | null | true | true | unknown | unknown | unknown | null | null | null | null | null |
3nzh | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 07/16/10 | Crystal structure of anti-emmprin antibody 5F6 FAB | HOMO SAPIENS, MUS MUSCULUS | homo sapiens, mus musculus | homo sapiens, mus musculus | null | Teplyakov, A., Obmolova, G., Malia, T., Gilliland, G.L. | 2.0 | X-RAY DIFFRACTION | 0.243 | 0.195 | false | true | IGHV6 | IGKV6 | Kappa | null | null | null | null | null |
2mkw | null | A | 11 | null | null | null | null | IMMUNE SYSTEM | 02/13/14 | Solution Structure of 6aJl2 and 6aJL2-R24G Amyloidogenics Light Chain Proteins | HOMO SAPIENS | null | homo sapiens | null | Amero, C., Maya-Martinez, R.C., Gil-Rodriguez, P.C. | NOT | SOLUTION NMR | null | null | false | true | null | IGLV6 | Lambda | null | null | null | null | null |
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