pdb stringlengths 4 4 | Hchain stringclasses 59
values | Lchain stringclasses 60
values | model int64 0 76 | antigen_chain stringclasses 386
values | antigen_type stringclasses 24
values | antigen_het_name stringclasses 240
values | antigen_name stringlengths 1 396 ⌀ | short_header stringclasses 448
values | date stringlengths 8 8 | compound stringlengths 4 243 | organism stringlengths 3 175 ⌀ | heavy_species stringclasses 121
values | light_species stringclasses 67
values | antigen_species stringclasses 937
values | authors stringlengths 6 762 | resolution stringlengths 1 8 | method stringclasses 10
values | r_free stringclasses 354
values | r_factor stringclasses 342
values | scfv bool 2
classes | engineered bool 2
classes | heavy_subclass stringclasses 14
values | light_subclass stringclasses 35
values | light_ctype stringclasses 3
values | affinity float64 0 0 ⌀ | delta_g float64 -16.91 -5.04 ⌀ | affinity_method stringclasses 11
values | temperature float64 4 37 ⌀ | pmid stringclasses 157
values |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
2fee | I | L | 0 | B | protein | null | h(+)/cl(-) exchange transporter clca | PROTON TRANSPORT,MEMBRANE PROTEIN | 12/15/05 | Structure of the Cl-/H+ exchanger CLC-ec1 from E.Coli in NaBr | ESCHERICHIA COLI; HOMO SAPIENS | homo sapiens | homo sapiens | escherichia coli | Accardi, A., Walden, M.P., Nguitragool, W., Jayaram, H., Williams, C., Miller, C. | 3.2 | X-RAY DIFFRACTION | 0.293 | 0.251 | false | true | IGHV3 | IGKV6D | Kappa | null | null | null | null | null |
3qeg | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 01/20/11 | Crystal structure of human N12-i2 Fab, an ADCC and neutralizing anti-HIV-1 Env antibody | HOMO SAPIENS | homo sapiens | homo sapiens | null | Guan, Y., DeVico, A.L., Lewis, G.K., Pazgier, M. | 1.95 | X-RAY DIFFRACTION | 0.236 | 0.203 | false | false | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
5o04 | F | null | 0 | A | protein | null | capsid protein | VIRAL PROTEIN | 05/16/17 | GII.10 Vietnam 026 norovirus protruding domain in complex with Nanobody Nano-26 and Nano-85 | NORWALK VIRUS; VICUGNA PACOS | vicugna pacos | null | norwalk virus | Koromyslova, A.D., Hansman, A.D. | 2.3 | X-RAY DIFFRACTION | 0.242 | 0.212 | false | true | IGHV1 | null | null | null | null | null | null | null |
6u0n | P | Q | 0 | C | protein | null | envelope glycoprotein gp120 | VIRAL PROTEIN | 08/14/19 | Asymmetrically open conformational state (Class II) of HIV-1 Env trimer BG505 SOSIP.664 in complex with sCD4 and E51 Fab | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Yang, Z., Bjorkman, P.J. | 3.5 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
6cdi | M | N | 0 | C | protein | null | glycoprotein 120 | VIRAL PROTEIN | 02/08/18 | Cryo-EM structure at 3.6 A resolution of vaccine-elicited antibody vFP16.02 in complex with HIV-1 Env BG505 DS-SOSIP, and antibodies VRC03 and PGT122 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Acharya, P., Xu, K., Liu, K., Carragher, B., Potter, C.S., Kwong, P.D. | 3.6 | ELECTRON MICROSCOPY | null | null | false | true | unknown | unknown | unknown | null | null | null | null | null |
7ldd | N | M | 0 | B | protein | null | glutamate receptor | MEMBRANE PROTEIN/IMMUNE SYSTEM | 01/13/21 | native AMPA receptor | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Yu, J., Rao, P., Gouaux, E. | 3.4 | ELECTRON MICROSCOPY | null | null | false | true | IGHV2 | IGKV10 | Kappa | null | null | null | null | null |
5en2 | A | B | 0 | C | protein | null | pre-glycoprotein polyprotein gp complex | VIRAL PROTEIN/IMMUNE SYSTEM | 11/09/15 | Molecular basis for antibody-mediated neutralization of New World hemorrhagic fever mammarenaviruses | JUNIN MAMMARENAVIRUS; MUS MUSCULUS | mus musculus | mus musculus | junin mammarenavirus | Mahmutovic, S., Clark, L., Levis, S., Briggiler, A., Enria, D., Harrison, S.C., Abraham, J. | 1.821 | X-RAY DIFFRACTION | 0.224 | 0.181 | false | true | IGHV1 | IGKV6 | Kappa | null | null | null | null | null |
7dr4 | A | B | 0 | J | protein | null | interleukin-2 | IMMUNE SYSTEM | 12/25/20 | Complex of anti-human IL-2 antibody and human IL-2 | MUS MUSCULUS; HOMO SAPIENS | mus musculus | mus musculus | homo sapiens | Kim, M.S., Kim, J.E. | 2.49 | X-RAY DIFFRACTION | 0.258 | 0.195 | false | true | IGHV1 | IGKV17 | Kappa | null | null | null | null | null |
2imn | null | A | 0 | null | null | null | null | IMMUNOGLOBULIN | 03/30/92 | REFINED CRYSTAL STRUCTURE OF A RECOMBINANT IMMUNOGLOBULIN DOMAIN AND A COMPLEMENTARITY-DETERMINING REGION 1-GRAFTED MUTANT | MUS MUSCULUS | null | mus musculus | null | Steipe, B., Huber, R. | 1.97 | X-RAY DIFFRACTION | unknown | 0.149 | false | true | unknown | unknown | unknown | null | null | null | null | null |
7s0c | M | N | 0 | B | protein | null | spike glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 08/30/21 | Structure of the SARS-CoV-2 S 6P trimer in complex with neutralizing antibody N-612-017 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Barnes, C.O., Bjorkman, P.J. | 3.25 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
7cj2 | K | L | 0 | B | protein | null | chitinase 3-like 1 (cartilage glycoprotein-39), isoformcra_a | IMMUNE SYSTEM | 07/09/20 | Crystal structure of the Fab antibody complexed with human YKL-40 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Choi, S., Na, J.H., Lee, S.J., Woo, J.R., Kim, D.Y., Hong, J.T., Lee, W.K. | 2.7 | X-RAY DIFFRACTION | 0.269 | 0.212 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6cdi | h | l | 0 | c | protein | null | unknown | VIRAL PROTEIN | 02/08/18 | Cryo-EM structure at 3.6 A resolution of vaccine-elicited antibody vFP16.02 in complex with HIV-1 Env BG505 DS-SOSIP, and antibodies VRC03 and PGT122 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Acharya, P., Xu, K., Liu, K., Carragher, B., Potter, C.S., Kwong, P.D. | 3.6 | ELECTRON MICROSCOPY | null | null | false | false | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
6u3i | H | L | 0 | A | protein | null | proprotein convertase subtilisin/kexin type 9 | HYDROLASE/HYDROLASE INHIBITOR/IMMUNE SYSTEM | 08/21/19 | Design of organo-peptides as bipartite PCSK9 antagonists | HOMO SAPIENS; MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | homo sapiens | Ultsch, M.H., Kirchhofer, D. | 2.9 | X-RAY DIFFRACTION | 0.217 | 0.179 | false | true | IGHV1 | IGKV6 | Kappa | null | null | null | null | null |
3bdy | H | L | 0 | V | protein | null | vascular endothelial growth factor a | HORMONE | 11/15/07 | Dual specific bH1 Fab in complex with VEGF | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Bostrom, J.M., Wiesmann, C., Appleton, B.A. | 2.6 | X-RAY DIFFRACTION | 0.252 | 0.194 | false | true | IGHV3 | IGKV1 | Kappa | 0 | -8.89 | SPR | null | 19299620 |
7e8c | T | V | 0 | B | protein | null | spike glycoprotein | VIRAL PROTEIN | 03/01/21 | SARS-CoV-2 S-6P in complex with 9 Fabs | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Du, S., Xiao, J., Zhang, Z. | 3.16 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGLV3 | Lambda | null | null | null | null | null |
6u12 | B | null | 0 | A | protein | null | inlb | IMMUNE SYSTEM | 08/15/19 | VHH R303 C33A/C102A in complex withthe LRR domain of InlB | LISTERIA MONOCYTOGENES; CAMELUS DROMEDARIUS | camelus dromedarius | null | listeria monocytogenes | Mendoza, M.N., Jian, M., Toride King, M., Brooks, C.L. | 1.56 | X-RAY DIFFRACTION | 0.199 | 0.175 | false | true | IGHV1 | null | null | null | null | null | null | null |
6v80 | J | null | 0 | F | H | protein | protein | NA | NA | antigen-presenting glycoprotein cd1d | t cell receptor alpha variable 10, nkt tcr alpha chainfusion | IMMUNE SYSTEM | 12/10/19 | Crystal structure of human CD1d presenting alpha-Galactosylceramide in complex with NKT12 TCR and VHH nanobody 1D12 | HOMO SAPIENS; LAMA GLAMA | lama glama | null | homo sapiens | homo sapiens | Shahine, A., Rossjohn, J. | 3.53 | X-RAY DIFFRACTION | 0.254 | 0.195 | false | true | IGHV1 | null | null | null | null | null | null | null |
3lh2 | H | L | 0 | S | protein | null | 4e10_1vi7a_s0_002_n (t88) | IMMUNE SYSTEM | 01/21/10 | Crystal structure of HIV epitope-scaffold 4E10_1VI7A_S0_002_N 4E10 Fv complex | ARTIFICIAL GENE; HOMO SAPIENS | homo sapiens | homo sapiens | artificial gene | Holmes, M.A. | 2.65 | X-RAY DIFFRACTION | 0.270 | 0.222 | false | true | IGHV1 | IGKV3 | Kappa | 0 | -11.25 | SPR | null | 20826338 |
5grz | A | a | 0 | null | null | null | null | IMMUNE SYSTEM | 08/13/16 | Crystal structure of disulfide-bonded diabody | HOMO SAPIENS | homo sapiens | null | null | Kim, J.H., Song, D.H., Youn, S.J., Kim, J.W., Cho, G., Lee, H., Lee, J.O. | 2.7 | X-RAY DIFFRACTION | 0.301 | 0.246 | true | true | unknown | unknown | unknown | null | null | null | null | null |
7klc | D | C | 0 | A | protein | null | hiv-1 clade a bg505 gp120,hiv-1 clade a bg505 gp120 | VIRAL PROTEIN/IMMUNE SYSTEM | 10/29/20 | Crystal structure of M4H2K1 Fab bound to HIV-1 BG505 gp120 core and to 17b Fab | MUS MUSCULUS; HOMO SAPIENS; HUMAN IMMUNODEFICIENCY VIRUS 1 | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Kumar, S., Wilson, I.A. | 4.3 | X-RAY DIFFRACTION | 0.334 | 0.302 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
4hii | B | A | 0 | A | carbohydrate | GAL | polysaccharide | IMMUNE SYSTEM | 10/11/12 | Anti-Streptococcus pneumoniae 23F Fab 023.102 with bound rhamnose-galactose | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Bryson, S., Risnes, L., Damgupta, S, Thomson, C.A., Schrader, J.W., Pai, E.F. | 2.3 | X-RAY DIFFRACTION | 0.256 | 0.243 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
6glx | H | L | 0 | A | protein | null | galectin-10 | SUGAR BINDING PROTEIN | 05/23/18 | Structure of galectin-10 in complex with the Fab fragment of a Charcot-Leyden crystal solubilizing antibody, 4E8 | HOMO SAPIENS; LAMA GLAMA | lama glama | lama glama | homo sapiens | Verstraete, K., Verschueren, K., Savvides, S.N. | 3.396 | X-RAY DIFFRACTION | 0.360 | 0.303 | false | true | IGHV4 | IGLV3 | Lambda | null | null | null | null | null |
4eiz | D | null | 0 | A | protein | null | dihydrofolate reductase | OXIDOREDUCTASE/IMMUNE SYSTEM | 04/06/12 | Structure of Nb113 bound to apoDHFR | ESCHERICHIA COLI; LAMA GLAMA | lama glama | null | escherichia coli | Oyen, D., Srinivasan, V. | 2.2 | X-RAY DIFFRACTION | 0.224 | 0.171 | false | true | IGHV1 | null | null | 0 | -11.627287 | SPR | null | TBD |
3idn | B | A | 0 | C | peptide | null | gp41 mper peptide analog | IMMUNE SYSTEM | 07/21/09 | Crystal structure of the HIV-1 Cross Neutralizing Monoclonal Antibody 2F5 Fab' fragment in complex with gp41 Peptide analog ELD(Paf)WAS | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | null | Julien, J.-P., Bryson, S., Pai, E.F. | 2.25 | X-RAY DIFFRACTION | 0.238 | 0.220 | false | false | IGHV2 | IGKV1 | Kappa | null | null | null | null | null |
7wui | N | null | 0 | A | protein | null | mini-gs | MEMBRANE PROTEIN | 02/08/22 | Tethered peptide activation mechanism of adhesion GPCRs ADGRG2 and ADGRG4 | HOMO SAPIENS; LAMA GLAMA; MUS MUSCULUS; SYNTHETIC CONSTRUCT; SYNTHETIC CONSTRUCT | lama glama | null | homo sapiens | Guo, S.C., He, Q.T., Xiao, P., Sun, J.P., Yu, X. | 3.1 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | null | null | null | null | null | null | null |
1uz6 | F | E | 0 | null | null | null | null | IMMUNE SYSTEM | 03/05/04 | anti-Lewis X Fab fragment uncomplexed | MUS MUSCULUS | mus musculus | mus musculus | null | Van Roon, A.M.M., Pannu, N.S., De Vrind, J.P.M., Hokke, C.H., Deelder, A.M., Van Der marel, G.A., Van Boom, J.H., Abrahams, J.P. | 2.05 | X-RAY DIFFRACTION | 0.244 | 0.198 | false | false | IGHV4 | IGKV2 | Kappa | null | null | null | null | null |
1xgy | I | M | 0 | Q | peptide | null | rhodopsin epitope mimetic peptide | immune system | 09/17/04 | Crystal Structure of Anti-Meta I Rhodopsin Fab Fragment K42-41L | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | null | Piscitelli, C.L., Angel, T.E., Bailey, B.W., Lawerence, C.M. | 2.71 | X-RAY DIFFRACTION | 0.272 | 0.233 | false | false | IGHV1 | IGKV2 | Kappa | null | null | null | null | null |
7soa | H | L | 0 | A | protein | null | spike glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 10/29/21 | SARS-CoV-2 S NTD B.1.617.2 delta variant + S2L20 Local Refinement | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | McCallum, M., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 3.1 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
5xqy | null | C | 0 | null | null | null | null | IMMUNE SYSTEM | 06/07/17 | Structure of monomeric mutant of REI immunoglobulin light chain variable domain crystallized at pH 8 | HOMO SAPIENS | null | homo sapiens | null | Mine, S., Nakamura, T., Uegaki, K., Hamada, D. | 2.9 | X-RAY DIFFRACTION | 0.285 | 0.231 | false | true | null | IGKV1 | Kappa | null | null | null | null | null |
3fku | Y | y | 0 | B | A | protein | protein | NA | NA | hemagglutinin | hemagglutinin | VIRAL PROTEIN/IMMUNE SYSTEM | 12/17/08 | Crystal structure of influenza hemagglutinin (H5) in complex with a broadly neutralizing antibody F10 | INFLUENZA A VIRUS; HOMO SAPIENS | homo sapiens | null | influenza a virus | influenza a virus | Hwang, W.C., Santelli, E., Stec, B., Wei, G., Cadwell, G., Bankston, L.A., Sui, J., Perez, S., Aird, D., Chen, L.M., Ali, M., Murakami, A., Yammanuru, A., Han, T., Cox, N., Donis, R.O., Liddington, R.C., Marasco, W.A. | 3.2 | X-RAY DIFFRACTION | 0.286 | 0.232 | true | true | unknown | unknown | unknown | 0 | -13.48 | SPR | 25 | 19234466 |
1f4y | H | L | 0 | H | Hapten | MGU | 2-O-[2-O-METHYL-4-[2,4-DIHYDROXY-BUTYRAMIDO]-4,6-DIDEOXY-]-ALPHA-D-MANNOPYRANOSYL-[1-O-METHYL-4-[2,4-DIHYDROXY-BUTYRAMIDO]-4,6-DIDEOXY]-ALPHA-D-MANNOPYRANOSE | IMMUNE SYSTEM | 06/10/00 | CRYSTAL STRUCTURE OF AN ANTI-CARBOHYDRATE ANTIBODY DIRECTED AGAINST VIBRIO CHOLERAE O1 IN COMPLEX WITH ANTIGEN | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Alzari, P.M., Souchon, H. | 2.8 | X-RAY DIFFRACTION | 0.352 | 0.226 | false | false | IGHV5 | IGLV1 | Lambda | 0.000001 | -8.29 | Other | null | 10880560 |
7bu6 | B | null | 0 | A | protein | null | endolysin,endolysin,endolysin,beta-1 adrenergic receptorchimera | MEMBRANE PROTEIN | 04/04/20 | Structure of human beta1 adrenergic receptor bound to norepinephrine and nanobody 6B9 | ENTEROBACTERIA PHAGE T4; HOMO SAPIENS; CAMELIDAE MIXED LIBRARY | camelidae mixed library | null | enterobacteria phage t4, homo sapiens | Xu, X., Kaindl, J., Clark, M., Hubner, H., Hirata, K., Sunahara, R., Gmeiner, P., Kobilka, B.K., Liu, X. | 2.7 | X-RAY DIFFRACTION | 0.258 | 0.232 | false | true | IGHV1 | null | null | null | null | null | null | null |
5ukn | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 01/23/17 | Structure of unliganded anti-gp120 CD4bs antibody DH522UCA Fab | MACACA MULATTA | macaca mulatta | macaca mulatta | null | Nicely, N.I. | 1.75 | X-RAY DIFFRACTION | 0.202 | 0.167 | false | true | IGHV4 | IGLV2 | Lambda | null | null | null | null | null |
3cvh | Q | R | 0 | M | O | protein | peptide | NA | NA | h-2 class i histocompatibility antigen, k-b alpha chain | ovalbumin | IMMUNE SYSTEM | 04/18/08 | How TCR-like antibody recognizes MHC-bound peptide | MUS MUSCULUS; GALLUS GALLUS | mus musculus | mus musculus | mus musculus | gallus gallus | Mareeva, T., Martinez-Hackert, E., Sykulev, Y. | 2.9 | X-RAY DIFFRACTION | 0.296 | 0.219 | false | false | IGHV1 | IGKV13 | Kappa | null | null | null | null | null |
4m8q | H | L | 0 | C | protein | null | 4e10 epitope scaffold t117 | IMMUNE SYSTEM | 08/13/13 | Ontogeny of recognition specificity and functionality for the anti-HIV neutralizing antibody 4E10 | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | synthetic construct | Finton, K.A.K. | 2.89 | X-RAY DIFFRACTION | 0.302 | 0.261 | false | true | IGHV1 | IGKV3 | Kappa | 0 | -11.462795 | SPR | null | TBD |
4fab | H | L | 0 | H | Hapten | FDS | FLUORESCIN | IMMUNOGLOBULIN | 04/10/89 | THREE-DIMENSIONAL STRUCTURE OF A FLUORESCEIN-FAB COMPLEX CRYSTALLIZED IN 2-METHYL-2,4-PENTANEDIOL | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Herron, J.N., He, X., Mason, M.L., Vossjunior, E.W., Edmundson, A.B. | 2.7 | X-RAY DIFFRACTION | unknown | unknown | false | true | IGHV6 | IGKV1 | Kappa | 0 | -11.02 | Other | null | 2508085 |
6udj | Q | B | 0 | G | protein | null | envelope glycoprotein gp120 | VIRAL PROTEIN/IMMUNE SYSTEM | 09/19/19 | HIV-1 bNAb 1-18 in complex with BG505 SOSIP.664 and 10-1074 | HOMO SAPIENS; HUMAN IMMUNODEFICIENCY VIRUS 1 | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Abernathy, M.E., Barnes, C.O., Gristick, H.B., Bjorkman, P.J. | 2.5 | ELECTRON MICROSCOPY | null | null | false | true | IGHV4 | unknown | unknown | null | null | null | null | null |
6mg5 | null | B | 0 | B | Hapten | 6ZW | 7-(diethylamino)-4-methyl-2H-1-benzopyran-2-one | IMMUNE SYSTEM | 04/10/19 | Structure of full-length human lambda-6A light chain JTO in complex with coumarin 1 | HOMO SAPIENS | null | homo sapiens | homo sapiens | Morgan, G.J., Yan, N.L., Mortenson, D.E., Stanfield, R.L., Wilson, I.A., Kelly, J.W. | 1.8 | X-RAY DIFFRACTION | 0.263 | 0.204 | false | true | null | IGLV6 | Lambda | null | null | null | null | null |
4f58 | K | O | 0 | null | null | null | null | IMMUNE SYSTEM | 05/12/12 | Fab structure of a neutralizing antibody L3 from an early subtype A HIV-1 infected patient | HOMO SAPIENS | homo sapiens | homo sapiens | null | Pan, R.M., Kong, X.P. | 2.488 | X-RAY DIFFRACTION | 0.256 | 0.208 | false | false | IGHV3 | IGLV2 | Lambda | null | null | null | null | null |
4gay | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 07/26/12 | Structure of the broadly neutralizing antibody AP33 | MUS MUSCULUS | mus musculus | mus musculus | null | Potter, J.A., Owsianka, A., Jeffery, N., Matthews, D., Keck, Z., Lau, P., Foung, S.K.H., Taylor, G.L., Patel, A.H. | 2.65 | X-RAY DIFFRACTION | 0.320 | 0.243 | false | false | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
6gkd | S | null | 0 | R | protein | null | cystic fibrosis transmembrane conductance regulator | HYDROLASE | 05/18/18 | human NBD1 of CFTR in complex with nanobodies D12 and G3a | HOMO SAPIENS; LAMA GLAMA | lama glama | null | homo sapiens | Sigoillot, M., Overtus, M., Grodecka, M., Scholl, D., Garcia-Pino, A., Laeremans, T., He, L., Pardon, E., Hildebrandt, E., Urbatsch, I., Steyaert, J., Riordan, J.R., Govaerts, C. | 2.99 | X-RAY DIFFRACTION | 0.235 | 0.204 | false | true | IGHV1 | null | null | null | null | null | null | null |
7l6m | h | g | 0 | null | null | null | null | IMMUNE SYSTEM | 12/23/20 | Cryo-EM structure of DH898.1 Fab-dimer from local refinement of the Fab-dimer bound near the CD4 binding site of HIV-1 Env CH848 SOSIP trimer | MACACA MULATTA | macaca mulatta | macaca mulatta | null | Manne, K., Edwards, R.J., Acharya, P. | 4.7 | ELECTRON MICROSCOPY | null | null | false | false | unknown | IGKV2 | Kappa | null | null | null | null | null |
7p5v | H | null | 0 | B | protein | null | volume-regulated anion channel subunit lrrc8a | MEMBRANE PROTEIN | 07/15/21 | Structure of homomeric LRRC8A Volume-Regulated Anion Channel in complex with synthetic nanobody Sb1 | MUS MUSCULUS; SYNTHETIC CONSTRUCT | synthetic construct | null | mus musculus | Deneka, D., Rutz, S., Sawicka, M. | 3.06 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
3qct | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 01/17/11 | Crystal structure of the humanized apo LT3015 anti-lysophosphatidic acid antibody Fab fragment | HOMO SAPIENS | homo sapiens | homo sapiens | null | Fleming, J.K., Wojciak, J.M., Campbell, M.-A., Huxford, T. | 2.1493 | X-RAY DIFFRACTION | 0.287 | 0.238 | false | true | IGHV5 | IGKV2D | Kappa | null | null | null | null | null |
7r73 | A | null | 0 | G | protein | null | glycoprotein 120 | IMMUNE SYSTEM | 06/24/21 | Crystal structure of llama VHH antibody D7 in complex with HIV-1 gp120 core | HUMAN IMMUNODEFICIENCY VIRUS 1; LAMA GLAMA | lama glama | null | human immunodeficiency virus 1 | Zhou, T., Kwong, P.D. | 1.76 | X-RAY DIFFRACTION | 0.215 | 0.179 | false | true | IGHV1 | null | null | null | null | null | null | null |
6h16 | B | null | 0 | A | protein | null | low-density lipoprotein receptor-related protein 6 | SIGNALING PROTEIN | 07/11/18 | Structure of LRP6 P3E3P4E4 in complex with VHH L-P2-D07 | HOMO SAPIENS; LAMA GLAMA | lama glama | null | homo sapiens | Gros, P., van Scherpenzeel, R.C. | 2.9 | X-RAY DIFFRACTION | 0.252 | 0.211 | false | true | IGHV1 | null | null | null | null | null | null | null |
6cxl | M | K | 0 | M | carbohydrate | BMA | polysaccharide | IMMUNE SYSTEM | 04/03/18 | anti-HIV-1 Fab 2G12 in complex with glycopeptide 10F5 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Stanfield, R.L., Wilson, I.A. | 3.586 | X-RAY DIFFRACTION | 0.248 | 0.219 | false | true | unknown | IGKV1 | Kappa | null | null | null | null | null |
7qnd | L | null | 0 | C | protein | null | gamma-aminobutyric acid receptor subunit beta-3 | MEMBRANE PROTEIN | 12/20/21 | Cryo-EM structure of human full-length extrasynaptic beta3delta GABA(A)R in complex with THIP (gaboxadol), histamine and nanobody Nb25 | HOMO SAPIENS; LAMA GLAMA | lama glama | null | homo sapiens | Sente, A., Desai, R., Naydenova, K., Malinauskas, T., Jounaidi, Y., Miehling, J., Zhou, X., Masiulis, S., Hardwick, S.W., Chirgadze, D.Y., Miller, K.W., Aricescu, A.R. | 3.4 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
6ujb | E | F | 0 | B | A | protein | protein | NA | NA | integrin beta-8 | integrin alpha-v | SIGNALING PROTEIN/IMMUNE SYSTEM | 10/02/19 | Integrin alpha-v beta-8 in complex with the Fabs C6D4 and 11D12v2 | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | homo sapiens | Campbell, M.G., Cormier, A., Cheng, Y., Nishimura, S.L. | 3.51 | ELECTRON MICROSCOPY | null | null | false | true | IGHV9 | IGKV8 | Kappa | null | null | null | null | null |
6wgk | C | D | 0 | null | null | null | null | IMMUNE SYSTEM | 04/05/20 | Fab portion of dupilumab with Crystal Kappa design and intrachain disulfide | HOMO SAPIENS | homo sapiens | homo sapiens | null | Druzina, Z., Atwell, S., Pustilnik, A., Antonysamy, S., Ho, C., Lieu, R., Hendle, J., Benach, J., Wang, J. | 1.62 | X-RAY DIFFRACTION | 0.236 | 0.210 | false | true | IGHV3 | IGKV2 | Kappa | null | null | null | null | null |
5x8l | H | M | 0 | C | protein | null | programmed cell death 1 ligand 1 | IMMUNE SYSTEM | 03/03/17 | PD-L1 in complex with atezolizumab | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Heo, Y.S., Lee, H.T. | 3.1 | X-RAY DIFFRACTION | 0.256 | 0.208 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6nf5 | O | P | 0 | J | protein | null | hiv-1 env bg505 md64 n332-gt5 sosip gp120 | VIRAL PROTEIN/immune system | 12/18/18 | BG505 MD64 N332-GT5 SOSIP trimer in complex with BG18-like precursor HMP1 fragmentantigen binding and base-binding RM20A3 fragment antigen binding | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS; MACACA MULATTA | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Ozorowski, G., Torres, J.L., Steichen, J.M., Schief, W.R., Ward, A.B. | 3.71 | ELECTRON MICROSCOPY | null | null | false | true | IGHV4 | IGLV3 | Lambda | null | null | null | null | null |
2xt1 | B | null | 0 | A | protein | null | gag polyprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 10/03/10 | Crystal structure of the HIV-1 capsid protein C-terminal domain (146- 231) in complex with a camelid VHH. | HUMAN IMMUNODEFICIENCY VIRUS 1; VICUGNA PACOS | vicugna pacos | null | human immunodeficiency virus 1 | Igonet, S., Vaney, M.-C., Bartonova, V., Helma, J., Rothbauer, U., Leonhardt, H., Stura, E., Krausslich, H.-G., Rey, F.A. | 1.32 | X-RAY DIFFRACTION | 0.1835 | 0.1607 | false | true | IGHV1 | null | null | null | null | null | null | null |
6xsw | D | E | 0 | F | protein | null | neurogenic locus notch homolog protein 3 | SIGNALING PROTEIN/Immune System | 07/16/20 | Structure of the Notch3 NRR in complex with an antibody Fab Fragment | RATTUS NORVEGICUS; HOMO SAPIENS | rattus norvegicus | rattus norvegicus | homo sapiens | Bard, J. | 2.98 | X-RAY DIFFRACTION | 0.256 | 0.233 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6vo1 | I | K | 0 | D | protein | null | envelope glycoprotein gp120 | VIRAL PROTEIN | 01/29/20 | BG505 SOSIP.v5.2 in complex with rhesus macaque Fab RM20J | HUMAN IMMUNODEFICIENCY VIRUS 1; MACACA MULATTA | macaca mulatta | macaca mulatta | human immunodeficiency virus 1 | Cottrell, C.A., Ward, A.B. | 3.88 | ELECTRON MICROSCOPY | null | null | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
5d93 | C | B | 0 | A | protein | null | sulfhydryl oxidase 1 | OXIDOREDUCTASE | 08/18/15 | Oxidoreductase Fragment of Mouse QSOX1 in Complex with a FAb Fragment from a Mouse QSOX1-Specific Antibody | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Grossman, I., Fass, D. | 2.201 | X-RAY DIFFRACTION | 0.236 | 0.174 | false | true | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
6bit | I | K | 0 | H | protein | null | tyrosine-protein phosphatase non-receptor type substrate 1 | IMMUNE SYSTEM | 11/03/17 | SIRPalpha antibody complex | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | Ring, N.G., Herndler-Brandstetter, D., Weiskopf, K., Shan, L., Volkmer, J.P., George, B.M., Lietzenmayer, M., McKenna, K.M., Naik, T.J., McCarty, A., Zheng, Y., Ring, A.M., Flavell, R.A., Weissman, I.L. | 2.191 | X-RAY DIFFRACTION | 0.240 | 0.210 | false | false | IGHV14 | IGKV4 | Kappa | 0 | -11.712072 | SPR | null | TBD |
6nyq | H | L | 0 | C | protein | null | glycosylated lysosomal membrane protein | IMMUNE SYSTEM | 02/12/19 | Crystal structure of glycosylated lysosomal membrane protein (GLMP) luminal domain bound to a Fab fragment | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Huang, C.S., Boenig, G., Hymowitz, S.G. | 1.85 | X-RAY DIFFRACTION | 0.204 | 0.164 | false | true | IGHV1 | IGKV12 | Kappa | null | null | null | null | null |
1r70 | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 10/17/03 | Model of human IgA2 determined by solution scattering, curve fitting and homology modelling | HOMO SAPIENS | homo sapiens | homo sapiens | null | Furtado, P.B., Whitty, P.W., Robertson, A., Eaton, J.T., Almogren, A., Kerr, M.A., Woof, J.M., Perkins, S.J. | 30.0 | SOLUTION SCATTERING / HOMOLOGY MODEL | null | null | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
1vhp | A | null | 4 | null | null | null | null | IMMUNOGLOBULIN | 04/16/96 | VH-P8, NMR | HOMO SAPIENS | homo sapiens | null | null | Riechmann, L. | NOT | SOLUTION NMR | null | null | false | true | unknown | unknown | unknown | null | null | null | null | null |
4k07 | null | H | 0 | null | null | null | null | IMMUNE SYSTEM | 04/03/13 | Crystal structure of the amyloid-forming immunoglobulin AL-103 cis-proline 95 mutant | HOMO SAPIENS | null | homo sapiens | null | Thompson, J.R., Berkholz, D.S., Mahlum, E.W., Ramirez-Alvarado, M. | 2.83 | X-RAY DIFFRACTION | 0.236 | 0.202 | false | true | null | IGKV1 | Kappa | null | null | null | null | null |
6amm | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 08/10/17 | CAT192 Fab Insertion Mutant H0/L1 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Lord, D.M., Wei, R.R. | 2.8 | X-RAY DIFFRACTION | 0.303 | 0.247 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6ot1 | m | n | 0 | G | protein | null | bg505 gp120 | IMMUNE SYSTEM | 05/02/19 | Cryo-EM structure of vaccine-elicited antibody 0PV-b.01 in complex with HIV-1 Env BG505 DS-SOSIP and antibodies VRC03 and PGT122 | HUMAN IMMUNODEFICIENCY VIRUS 1; MACACA MULATTA; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Gorman, J., Kwong, P.D. | 3.5 | ELECTRON MICROSCOPY | null | null | false | false | IGHV4 | unknown | unknown | null | null | null | null | null |
4r7d | E | F | 0 | null | null | null | null | IMMUNE SYSTEM | 08/27/14 | Fab Hu 15C1 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Loyau, J., Didelot, G., Malinge, P., Ravn, U., Magistrelli, G., Depoisier, J.F., Kosco-Vilbois, M., Fischer, N., Thore, S., Rousseau, F. | 2.753 | X-RAY DIFFRACTION | 0.209 | 0.177 | false | true | IGHV4 | IGKV6 | Kappa | null | null | null | null | null |
6u02 | K | I | 0 | J | protein | null | neuraminidase | VIRAL PROTEIN/IMMUNE SYSTEM | 08/13/19 | CryoEM-derived model of NA-63 Fab in complex with N9 Shanghai2 | INFLUENZA A VIRUS (A/ENVIRONMENT/SHANGHAI/S1439/2013(H7N9)); HOMO SAPIENS | homo sapiens | homo sapiens | influenza a virus(a/environment/shanghai/s1439/2013(h7n9)) | Ward, A.B., Turner, H.L., Zhu, X. | 3.05 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
1fe8 | I | M | 0 | B | protein | null | von willebrand factor | IMMUNE SYSTEM | 07/21/00 | CRYSTAL STRUCTURE OF THE VON WILLEBRAND FACTOR A3 DOMAIN IN COMPLEX WITH A FAB FRAGMENT OF IGG RU5 THAT INHIBITS COLLAGEN BINDING | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | Bouma, B., Huizinga, E.G., Schiphorst, M.E., Sixma, J.J., Kroon, J., Gros, P. | 2.03 | X-RAY DIFFRACTION | 0.264 | 0.227 | false | false | IGHV2 | IGKV10 | Kappa | 0.000002 | -7.774786 | Unknown | null | TBD |
7lde | L | l | 0 | A | protein | null | glutamate receptor 1 | MEMBRANE PROTEIN | 01/13/21 | native AMPA receptor | MUS MUSCULUS | mus musculus | null | mus musculus | Yu, J., Rao, P., Gouaux, E. | 3.9 | ELECTRON MICROSCOPY | null | null | true | true | unknown | unknown | unknown | null | null | null | null | null |
6xq2 | C | B | 0 | A | protein | null | hemagglutinin | VIRAL PROTEIN/IMMUNE SYSTEM | 07/09/20 | Human antibody S8V2-37 in complex with the influenza hemagglutinin head domain of A/Texas/50/2012(H3N2) | INFLUENZA A VIRUS (A/TEXAS/50/2012(H3N2)); HOMO SAPIENS | homo sapiens | homo sapiens | influenza a virus (a/texas/50/2012(h3n2)) | McCarthy, K.R., Harrison, S.C. | 3.002 | X-RAY DIFFRACTION | 0.290 | 0.247 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6bhz | I | M | 0 | null | null | null | null | IMMUNE SYSTEM | 10/31/17 | Trastuzumab Fab D185A (Light Chain) Mutant. | HOMO SAPIENS | homo sapiens | homo sapiens | null | DiDonato, M., Spraggon, G. | 1.75 | X-RAY DIFFRACTION | 0.191 | 0.168 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
2rcj | J | K | 0 | null | null | null | null | IMMUNE SYSTEM | 09/20/07 | Solution structure of human Immunoglobulin M | HOMO SAPIENS | homo sapiens | homo sapiens | null | Perkins, S.J., Nealis, A.S., Sutton, B.J., Feinstein, A. | NOT | SOLUTION SCATTERING | null | null | false | false | IGHV3 | IGLV1 | Lambda | null | null | null | null | null |
7z1b | B | null | 0 | A | protein | null | spike protein s1 | ANTIVIRAL PROTEIN | 02/24/22 | Nanobody H11-A10 and F2 bound to RBD | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; LAMA GLAMA | lama glama | null | severe acute respiratory syndrome coronavirus2 | Mikolajek, H., Naismith, J.H. | 2.3 | X-RAY DIFFRACTION | 0.243 | 0.198 | false | true | IGHV1 | null | null | null | null | null | null | null |
4ckd | K | O | 0 | B | protein | null | beta-galactosidase | HYDROLASE/IMMUNE SYSTEM | 01/03/14 | Model of complex between the E.coli enzyme beta-galactosidase and four single chain Fv antibody domains scFv13R4. | MUS MUSCULUS; ESCHERICHIA COLI | mus musculus | mus musculus | escherichia coli | Vinothkumar, K.R., McMullan, G., Henderson, R. | 13.0 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV5 | Kappa | null | null | null | null | null |
7bb6 | B | null | 0 | C | E | protein | protein | NA | NA | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | guanine nucleotide-binding protein g(s) subunit alphaisoforms short | MEMBRANE PROTEIN | 12/17/20 | AVP-V2R-Galphas-beta1-gamma2-Nb35 (L state) | HOMO SAPIENS; LAMA GLAMA; SYNTHETIC CONSTRUCT | lama glama | null | homo sapiens | homo sapiens | Bous, J., Mouillac, B., Bron, P., Granier, S. | 4.2 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | null | null | null | null | null | null | null |
6nnf | D | E | 0 | B | protein | null | envelope glycoprotein gp41 | IMMUNE SYSTEM | 01/14/19 | Crystal Structure of HIV-1 BG505 SOSIP.664 Prefusion Env Trimer Bound to VRC01 FR3-03 scFv in Complex with Crystallization Chaperones 3H109L Fab and 35O22 scFv at 3.5 Angstrom | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Lai, Y.-T., Kwong, P.D. | 2.762 | X-RAY DIFFRACTION | 0.298 | 0.242 | false | true | unknown | unknown | unknown | null | null | null | null | null |
4y7m | A | null | 0 | C | protein | null | type vi secretion protein icmf | MEMBRANE PROTEIN | 02/15/15 | T6SS protein TssM C-terminal domain (835-1129) from EAEC | LAMA GLAMA; ESCHERICHIA COLI 2-156-04_S3_C3 | lama glama | null | escherichia coli 2-156-04_s3_c3 | Nguyen, V.S., Spinelli, S., Durand, E., Roussel, A., Cambillau, C. | 1.92 | X-RAY DIFFRACTION | 0.211 | 0.183 | false | true | IGHV1 | null | null | null | null | null | null | null |
3f7v | A | B | 0 | C | protein | null | voltage-gated potassium channel | membrane protein/metal transport | 11/10/08 | KcsA Potassium channel in the open-inactivated state with 23 A opening at T112 | STREPTOMYCES LIVIDANS; MUS MUSCULUS | mus musculus | mus musculus | streptomyces lividans | Cuello, L.G., Jogini, V., Cortes, D.M., Perozo, E. | 3.2 | X-RAY DIFFRACTION | 0.276 | 0.259 | false | false | IGHV1 | IGKV5 | Kappa | null | null | null | null | null |
1oay | null | M | 0 | null | null | null | null | IMMUNE SYSTEM | 01/21/03 | Antibody multispecificity mediated by conformational diversity | RATTUS RATTUS | null | rattus rattus | null | James, L.C., Roversi, P., Tawfik, D. | 2.66 | X-RAY DIFFRACTION | 0.280 | 0.258 | false | true | unknown | unknown | unknown | 0.000001 | null | Other | 20 | 12610298 |
2hkh | H | L | 0 | null | null | null | null | immune system | 07/04/06 | Crystal structure of the Fab M75 | MUS MUSCULUS | mus musculus | mus musculus | null | Kral, V., Mader, P., Stouracova, R., Fabry, M., Sedlacek, J., Brynda, J. | 2.1 | X-RAY DIFFRACTION | 0.273 | 0.219 | false | false | IGHV10 | IGKV1 | Kappa | null | null | null | null | null |
4m7z | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 08/12/13 | Unliganded 1 crystal structure of S25-26 Fab | MUS MUSCULUS | mus musculus | mus musculus | null | Haji-Ghassemi, O., Evans, S.V., Muller-Loennies, S., Saldova, R., Muniyappa, M., Brade, L., Rudd, P.M., Harvey, D.J., Kosma, P., Brade, H. | 2.75 | X-RAY DIFFRACTION | 0.238 | 0.216 | false | false | IGHV2 | IGKV1 | Kappa | null | null | null | null | null |
5zuf | E | D | 0 | C | A | protein | protein | NA | NA | vp3 | capsid protein vp1 | VIRUS LIKE PARTICLE | 05/07/18 | Fit R10 Fab coordinates into the cryo-EM of EV71 in complex with A9 | ENTEROVIRUS A71; MUS MUSCULOIDES | mus musculoides | mus musculoides | enterovirus a71 | enterovirus a71 | Wang, X., Zhu, L., Wang, N. | 6.8 | ELECTRON MICROSCOPY | null | null | false | true | IGHV5 | IGKV4 | Kappa | null | null | null | null | null |
3sgd | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 06/14/11 | Crystal structure of the mouse mAb 17.2 | MUS MUSCULUS | mus musculus | mus musculus | null | Pizarro, J.C., Boulot, G., Hontebeyrie, M., Bentley, G.A. | 2.31 | X-RAY DIFFRACTION | 0.235 | 0.172 | false | true | IGHV10 | IGKV1 | Kappa | null | null | null | null | null |
3ivk | A | B | 0 | C | nucleic-acid | null | class i ligase product | immune system / RNA | 09/01/09 | Crystal Structure of the Catalytic Core of an RNA Polymerase Ribozyme Complexed with an Antigen Binding Antibody Fragment | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | null | Koldobskaya, Y., Duguid, E.M., Shechner, D.M., Koide, S., Kossiakoff, A.A., Bartel, D.P., Piccirilli, J.A. | 3.1 | X-RAY DIFFRACTION | 0.225 | 0.207 | false | true | IGHV5 | IGKV15 | Kappa | null | null | null | null | null |
5kem | B | C | 0 | A | protein | null | ebola secreted glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 06/09/16 | EBOV sGP in complex with variable Fab domains of IgGs c13C6 and BDBV91 | HOMO SAPIENS; ZAIRE EBOLAVIRUS | homo sapiens | homo sapiens | zaire ebolavirus | Pallesen, J., Murin, C.D., de Val, N., Cottrell, C.A., Hastie, K.M., Turner, H.L., Fusco, M.L., Flyak, A.I., Zeitlin, L., Crowe Jr., J.E., Andersen, K.G., Saphire, E.O., Ward, A.B. | 5.5 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
5nml | C | null | 0 | null | null | null | null | IMMUNE SYSTEM | 04/06/17 | Nb36 Ser85Cys with Hg bound | LAMA GLAMA | lama glama | null | null | Hansen, S.B., Andersen, K.R., Laursen, N.S., Andersen, G.R. | 2.5 | X-RAY DIFFRACTION | 0.265 | 0.238 | false | true | IGHV1 | null | null | null | null | null | null | null |
4d9q | E | D | 0 | B | protein | null | factor d | HYDROLASE/IMMUNE SYSTEM | 01/11/12 | Inhibiting Alternative Pathway Complement Activation by Targeting the Exosite on Factor D | MACACA MULATTA; HOMO SAPIENS | homo sapiens | homo sapiens | macaca mulatta | Murray, J.M., Wiesmann, C. | 2.28 | X-RAY DIFFRACTION | 0.230 | 0.189 | false | true | IGHV7 | IGKV1 | Kappa | 0 | -14.355775 | SPR | null | TBD |
5nbd | C | null | 0 | B | A | protein | protein | NA | NA | wlab protein | wlab protein | TRANSPORT PROTEIN | 03/01/17 | PglK flippase in complex with inhibitory nanobody | LAMA GLAMA; CAMPYLOBACTER JEJUNI | lama glama | null | campylobacter jejuni | campylobacter jejuni | Perez, C., Pardon, E., Steyaert, J., Locher, K.P. | 3.9 | X-RAY DIFFRACTION | 0.335 | 0.311 | false | true | IGHV3 | null | null | null | null | null | null | null |
5i8h | E | F | 0 | B | protein | null | bg505 sosip.664 gp41 | IMMUNE SYSTEM | 02/18/16 | Crystal Structure of HIV-1 BG505 SOSIP.664 Prefusion Env Trimer in Complex with V3 Loop-targeting Antibody PGT122 Fab and Fusion Peptide-targeting Antibody VRC34.01 Fab | HOMO SAPIENS; HUMAN IMMUNODEFICIENCY VIRUS 1 | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Xu, K., Zhou, T., Kwong, P.D. | 4.301 | X-RAY DIFFRACTION | 0.309 | 0.281 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
5jw4 | M | N | 0 | B | A | protein | protein | NA | NA | hemagglutinin | hemagglutinin | IMMUNE SYSTEM | 05/11/16 | Structure of MEDI8852 Fab Fragment in Complex with H5 HA | INFLUENZA A VIRUS; HOMO SAPIENS | homo sapiens | homo sapiens | influenza a virus | influenza a virus | Neu, U., Collins, P.J., Walker, P.A., Vorlaender, M.K., Ogrodowicz, R.W., Martin, S.R., Gamblin, S.J., Skehel, J.J. | 3.7 | X-RAY DIFFRACTION | 0.285 | 0.274 | false | true | IGHV6 | IGKV1 | Kappa | null | null | null | null | null |
7dd2 | E | H | 0 | K | D | protein | protein | NA | NA | sars-cov2-s protein | sars-cov2-s protein | VIRAL PROTEIN | 10/27/20 | S-3C1-F2 structure, two RBDs are up and one RBD is down, the two up RBD bind with a 3C1 fab. | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; MUS MUSCULUS | mus musculus | mus musculus | severe acute respiratory syndrome coronavirus2 | severe acute respiratory syndrome coronavirus2 | Cong, Y., Liu, C.X. | 5.6 | ELECTRON MICROSCOPY | null | null | false | false | IGHV3 | IGKV6 | Kappa | null | null | null | null | null |
5c7k | E | F | 0 | C | D | protein | protein | NA | NA | envelope glycoprotein gp120 | envelope glycoprotein gp41 | IMMUNE SYSTEM | 06/24/15 | Crystal structure BG505 SOSIP gp140 HIV-1 Env trimer bound to broadly neutralizing antibodies PGT128 and 8ANC195 | HOMO SAPIENS; HUMAN IMMUNODEFICIENCY VIRUS 1 | homo sapiens | homo sapiens | human immunodeficiency virus 1 | human immunodeficiency virus 1 | Kong, L., Stanfield, R.L., Wilson, I.A. | 4.6019 | X-RAY DIFFRACTION | 0.295 | 0.289 | false | true | unknown | IGKV1 | Kappa | null | null | null | null | null |
5ken | J | I | 0 | E | protein | null | ebola surface glycoprotein, gp1 | VIRAL PROTEIN/IMMUNE SYSTEM | 06/09/16 | EBOV GP in complex with variable Fab domains of IgGs c4G7 and c13C6 | HOMO SAPIENS; ZAIRE EBOLAVIRUS (STRAIN MAYINGA-76); ZAIRE EBOLAVIRUS | homo sapiens | homo sapiens | zaire ebolavirus | Pallesen, J., Murin, C.D., de Val, N., Cottrell, C.A., Hastie, K.M., Turner, H.L., Fusco, M.L., Flyak, A.I., Zeitlin, L., Crowe Jr., J.E., Andersen, K.G., Saphire, E.O., Ward, A.B. | 4.3 | ELECTRON MICROSCOPY | null | null | false | true | IGHV8 | IGKV6 | Kappa | null | null | null | null | null |
7rmi | N | null | 0 | A | B | protein | protein | NA | NA | guanine nucleotide-binding protein g(s) subunit alphaisoforms short, with certain residues mutated to match guanine nucleotide-binding protein g(q) subunit | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | SIGNALING PROTEIN/MEMBRANE PROTEIN | 07/27/21 | SP6-11 biased agonist bound to active human neurokinin 1 receptor in complex with miniGs/q70 | HOMO SAPIENS; LAMA GLAMA; SYNTHETIC CONSTRUCT | lama glama | null | homo sapiens | homo sapiens | Harris, J.A., Faust, B., Gondin, A.B., Daemgen, M.A., Suomivuori, C.M., Veldhuis, N.A., Cheng, Y., Dror, R.O., Thal, D., Manglik, A. | 3.2 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | null | null | null | null | null | null | null |
5dsc | A | B | 0 | Q | peptide | null | peptide | IMMUNE SYSTEM | 09/17/15 | Context-independent anti-hypusine antibody FabHpu24.B in complex with hypusine | ORYCTOLAGUS CUNICULUS; SYNTHETIC CONSTRUCT | oryctolagus cuniculus | oryctolagus cuniculus | synthetic construct | Zhai, Q., Carter, P.J. | 2.4 | X-RAY DIFFRACTION | 0.248 | 0.207 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
6arp | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 08/23/17 | Structure of a mutant Cetuximab Fab fragment | HOMO SAPIENS | homo sapiens | homo sapiens | null | Christie, M., Christ, D. | 1.7 | X-RAY DIFFRACTION | 0.197 | 0.172 | false | true | IGHV2 | IGKV5 | Kappa | null | null | null | null | null |
6mhg | J | U | 0 | E | protein | null | circumsporozoite protein | IMMUNE SYSTEM | 09/17/18 | Cryo-EM structure of the circumsporozoite protein of Plasmodium falciparum with a vaccine-elicited antibody reveals maturation of inter-antibody contacts | PLASMODIUM FALCIPARUM; HOMO SAPIENS | homo sapiens | homo sapiens | plasmodium falciparum | Cottrell, C.A., Torres, J.L., Ward, A.B. | 3.57 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGLV1 | Lambda | null | null | null | null | null |
5tsj | 2 | null | 0 | G | I | protein | protein | NA | NA | v-type atp synthase subunit e | v-type atpase subunit g | membrane protein, hydrolase | 10/29/16 | Thermus thermophilus V/A-ATPase bound to VH dAbs | HOMO SAPIENS; THERMUS THERMOPHILUS (STRAIN HB8 / ATCC 27634 / DSM 579) | homo sapiens | null | thermus thermophilus (strain hb8 / atcc 27634 /dsm 579) | thermus thermophilus (strain hb8 / atcc 27634 /dsm 579) | Davies, R.B., Smits, C., Wong, A.S.W., Stock, D., Sandin, S., Stewart, A.G. | 8.7 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | null | null | null | null | null | null | null |
2hh0 | H | L | 0 | P | peptide | null | prion protein | IMMUNE SYSTEM | 06/27/06 | Structure of an Anti-PrP Fab, P-Clone, in Complex with its Cognate Bovine Peptide Epitope. | MUS MUSCULUS, HOMO SAPIENS; SYNTHETIC CONSTRUCT | mus musculus, homo sapiens | mus musculus, homo sapiens | null | Kanyo, Z.K. | 2.85 | X-RAY DIFFRACTION | 0.282 | 0.222 | true | true | IGHV14 | IGKV9 | Kappa | null | null | null | null | null |
7eb2 | N | n | 0 | A | B | protein | protein | NA | NA | guanine nucleotide-binding protein g(i) subunit alpha-1 | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | MEMBRANE PROTEIN | 03/08/21 | Cryo-EM structure of human GABA(B) receptor-Gi protein complex | HOMO SAPIENS; SYNTHETIC CONSTRUCT | synthetic construct | null | homo sapiens | homo sapiens | Shen, C., Mao, C., Xu, C., Jin, N., Zhang, H., Shen, D., Shen, Q., Wang, X., Hou, T., Rondard, P., Chen, Z., Pin, J., Zhang, Y., Liu, J. | 3.5 | ELECTRON MICROSCOPY | null | null | true | true | unknown | unknown | unknown | null | null | null | null | null |
7m7f | E | F | 0 | B | protein | null | eryai,6-deoxyerythronolide-b synthase erya3, modules 5 and6 chimera | BIOSYNTHETIC PROTEIN/IMMUNE SYSTEM | 03/28/21 | 6-Deoxyerythronolide B synthase (DEBS) module 1 in complex with antibody fragment 1B2: State 1 | SACCHAROPOLYSPORA ERYTHRAEA; HOMO SAPIENS | homo sapiens | homo sapiens | saccharopolyspora erythraea | Cogan, D.P., Zhang, K., Chiu, W., Khosla, C. | 3.2 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV2 | Kappa | null | null | null | null | null |
3j2x | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 01/28/13 | Electron Cryo-microscopy of Chikungunya VLP in complex with neutralizing antibody Fab m242 | MUS MUSCULUS | mus musculus | mus musculus | null | Sun, S., Xiang, Y., Rossmann, M.G. | 15.6 | ELECTRON MICROSCOPY | null | null | false | false | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
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