pdb stringlengths 4 4 | Hchain stringclasses 59
values | Lchain stringclasses 60
values | model int64 0 76 | antigen_chain stringclasses 386
values | antigen_type stringclasses 24
values | antigen_het_name stringclasses 240
values | antigen_name stringlengths 1 396 ⌀ | short_header stringclasses 448
values | date stringlengths 8 8 | compound stringlengths 4 243 | organism stringlengths 3 175 ⌀ | heavy_species stringclasses 121
values | light_species stringclasses 67
values | antigen_species stringclasses 937
values | authors stringlengths 6 762 | resolution stringlengths 1 8 | method stringclasses 10
values | r_free stringclasses 354
values | r_factor stringclasses 342
values | scfv bool 2
classes | engineered bool 2
classes | heavy_subclass stringclasses 14
values | light_subclass stringclasses 35
values | light_ctype stringclasses 3
values | affinity float64 0 0 ⌀ | delta_g float64 -16.91 -5.04 ⌀ | affinity_method stringclasses 11
values | temperature float64 4 37 ⌀ | pmid stringclasses 157
values |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
7n4i | H | L | 0 | C | protein | null | spike protein s1 | VIRAL PROTEIN/IMMUNE SYSTEM | 06/04/21 | Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing human antibody WRAIR-2057. | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Sankhala, R.S., Joyce, M.G. | 2.284 | X-RAY DIFFRACTION | 0.238 | 0.200 | false | true | IGHV5 | IGKV1 | Kappa | null | null | null | null | null |
7niv | E | D | 0 | A | protein | null | isoform 2 of phosphatidylcholine translocator abcb4 | PROTEIN TRANSPORT | 02/14/21 | Nanodisc reconstituted human ABCB4 in complex with 4B1-Fab and QA2-Fab (phosphatidylcholine-bound, occluded conformation) | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Nosol, K., Locher, K.P. | 3.6 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
7wpf | R | S | 0 | B | protein | null | spike glycoprotein | VIRAL PROTEIN | 01/23/22 | SARS-CoV-2 Omicron Variant S Trimer complexed with three JMB2002 Fab | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; MUS MUSCULUS; LAMA GLAMA | mus musculus | mus musculus | severe acute respiratory syndrome coronavirus2 | Yin, W., Xu, Y., Xu, P., Cao, X., Wu, C., Gu, C., He, X., Wang, X., Huang, S., Yuan, Q., Wu, K., Hu, W., Huang, Z., Liu, J., Wang, Z., Jia, F., Xia, K., Liu, P., Wang, X., Song, B., Zheng, J., Jiang, H., Cheng, X., Jiang, Y., Deng, S.J., Xu, H.E. | 2.92 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
7vaf | H | L | 0 | A | protein | null | sodium/bile acid cotransporter | TRANSPORT PROTEIN | 08/29/21 | Cryo-EM structure of Rat NTCP complexed with YN69202Fab | MUS MUSCULUS; RATTUS NORVEGICUS | mus musculus | mus musculus | rattus norvegicus | Asami, J., Shimizu, T., Ohto, U. | 3.11 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV8 | Kappa | null | null | null | null | null |
7dwu | H | L | 0 | A | protein | null | envelope protein | VIRUS/IMMUNE SYSTEM | 01/18/21 | Cryo-EM structure of Dengue virus serotype 1 strain WestPac 74 in complex with human antibody 1C19 Fab at 37 deg C (Class 2 particle) | DENGUE VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | dengue virus 1 | Fibriansah, G., Ng, T.S., Kostyuchenko, V.A., Shi, J., Lok, S.M. | 19 | ELECTRON MICROSCOPY | null | null | false | false | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
2vdp | H | L | 0 | A | protein | null | integrin alpha-iib | CELL ADHESION/IMMUNE SYSTEM | 10/10/07 | Integrin AlphaIIbBeta3 Headpiece Bound to Fibrinogen Gamma chain peptide,LGGAKQAGDV | HOMO SAPIENS; MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | homo sapiens | Springer, T., Zhu, J., Xiao, T. | 2.8 | X-RAY DIFFRACTION | 0.204 | 0.156 | false | false | IGHV14 | IGKV14 | Kappa | null | null | null | null | null |
6ivz | H | L | 0 | A | protein | null | envelope protein | VIRAL PROTEIN/IMMUNE SYSTEM | 12/04/18 | Crystal structure of 5A ScFv complexed with YFV-China sE in postfusion state | YELLOW FEVER VIRUS; HOMO SAPIENS | homo sapiens | homo sapiens | yellow fever virus | Lu, X.S., Xiao, H.X., Li, S.H., Pang, X.F. | 2.4 | X-RAY DIFFRACTION | 0.256 | 0.210 | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
4r7d | I | J | 0 | null | null | null | null | IMMUNE SYSTEM | 08/27/14 | Fab Hu 15C1 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Loyau, J., Didelot, G., Malinge, P., Ravn, U., Magistrelli, G., Depoisier, J.F., Kosco-Vilbois, M., Fischer, N., Thore, S., Rousseau, F. | 2.753 | X-RAY DIFFRACTION | 0.209 | 0.177 | false | true | IGHV4 | IGKV6 | Kappa | null | null | null | null | null |
5j3d | C | D | 0 | I | G | protein | protein | NA | NA | fusion glycoprotein f0 | fusion glycoprotein f0 | IMMUNE SYSTEM | 03/30/16 | Crystal structure of human Fab 14N4 in complex with post-fusion RSV F | HOMO SAPIENS; HUMAN RESPIRATORY SYNCYTIAL VIRUS A | homo sapiens | homo sapiens | human respiratory syncytial virus a | human respiratory syncytial virus a | Mousa, J.J., Crowe, J.E. | 4.077 | X-RAY DIFFRACTION | 0.282 | 0.257 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6j5d | H | L | 0 | A | protein | null | envelope | VIRAL PROTEIN/IMMUNE SYSTEM | 01/10/19 | Complex structure of MAb 4.2-scFv with louping ill virus envelope protein Domain III | LOUPING ILL VIRUS; MUS MUSCULUS | mus musculus | mus musculus | louping ill virus | Yang, X., Qi, J., Peng, R., Dai, L., Gould, E.A., Tien, P., Gao, G.F. | 1.8 | X-RAY DIFFRACTION | 0.189 | 0.170 | false | true | IGHV1 | IGKV12 | Kappa | null | null | null | null | null |
1ynt | B | A | 0 | F | E | protein | protein | NA | NA | major surface antigen p30 | protein l | IMMUNE SYSTEM | 01/25/05 | Structure of the immunodominant epitope displayed by the surface antigen 1 (SAG1) of Toxoplasma gondii complexed to a monoclonal antibody | FINEGOLDIA MAGNA; TOXOPLASMA GONDII; MUS MUSCULUS | mus musculus | mus musculus | toxoplasma gondii | finegoldia magna | Graille, M., Stura, E.A., Bossus, M., Muller, B.H., Letourneur, O., Battail-Poirot, N, Sibai, G., Rolland, D., Le Du, M.H., Ducancel, F. | 3.1 | X-RAY DIFFRACTION | 0.283 | 0.241 | false | false | IGHV1 | IGKV10 | Kappa | null | null | null | null | null |
5esv | A | B | 0 | E | protein | null | 2-c-methyl-d-erythritol 2,4-cyclodiphosphate synthase,envelope glycoprotein gp160 | IMMUNE SYSTEM | 11/17/15 | Crystal Structure of Broadly Neutralizing Antibody CH03, Isolated from Donor CH0219, in Complex with Scaffolded Trimeric HIV-1 Env V1V2 Domain from the Clade C Superinfecting Strain of Donor CAP256. | HOMO SAPIENS; HAEMOPHILUS INFLUENZAE | homo sapiens | homo sapiens | haemophilus influenzae, human immunodeficiencyvirus 1, haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd) | Gorman, J., Yang, M., Kwong, P.D. | 3.105 | X-RAY DIFFRACTION | 0.259 | 0.209 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
6zcz | H | L | 0 | E | protein | null | spike glycoprotein | VIRAL PROTEIN | 06/12/20 | Crystal structure of receptor binding domain of SARS-CoV-2 Spike glycoprotein in ternary complex with EY6A Fab and a nanobody. | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; LAMA GLAMA; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Zhou, D., Zhao, Y., Fry, E.E., Ren, J., Stuart, D.I. | 2.65 | X-RAY DIFFRACTION | 0.260 | 0.215 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
1cd0 | null | B | 0 | null | null | null | null | IMMUNE SYSTEM | 03/05/99 | STRUCTURE OF HUMAN LAMDA-6 LIGHT CHAIN DIMER JTO | HOMO SAPIENS | null | homo sapiens | null | Pokkuluri, P.R., Solomon, A., Weiss, D.T., Stevens, F.J., Schiffer, M. | 1.9 | X-RAY DIFFRACTION | 0.240 | 0.184 | false | true | null | IGLV6 | Lambda | null | null | null | null | null |
4w68 | A | null | 0 | null | null | null | null | IMMUNE SYSTEM | 08/20/14 | Cytoplasmically Produced Homodimeric Single Domain Antibody (sdAb) C22A/C99V variant against Staphylococcal enterotoxin B (SEB) | LAMA GLAMA | lama glama | null | null | George, J., Legler, P.M. | 2.0 | X-RAY DIFFRACTION | 0.242 | 0.199 | false | true | IGHV1 | null | null | null | null | null | null | null |
7nw3 | H | L | 0 | A | peptide | null | region from c-c chemokine receptor type 5 n-terminaldomain | IMMUNE SYSTEM | 03/16/21 | X-ray crystallographic study of PIYDIN, which contains the truncation determinants of binding PI and N, bound to RoAb13, a CCR5 antibody | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | homo sapiens | Saridakis, E., Helliwell, J.R., Govada, L., Chayen, N.E. | 3.20001 | X-RAY DIFFRACTION | 0.293 | 0.268 | false | false | IGHV5 | IGKV8 | Kappa | null | null | null | null | null |
3nfs | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 06/10/10 | Crystal structure the Fab fragment of therapeutic antibody daclizumab | HOMO SAPIENS | homo sapiens | homo sapiens | null | Yang, H., Wang, J., Du, J., Zhong, C., Guo, Y., Ding, J. | 2.6 | X-RAY DIFFRACTION | 0.275 | 0.225 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
6bla | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 11/09/17 | Structure of AMM01 Fab, an anti EBV gH/gL neutralizing antibody | HOMO SAPIENS | homo sapiens | homo sapiens | null | Pancera, M., Weidle, C. | 1.55 | X-RAY DIFFRACTION | 0.194 | 0.166 | false | true | IGHV1 | IGLV3 | Lambda | null | null | null | null | null |
6gg0 | H | L | 0 | 4 | 3 | protein | protein | NA | NA | capsid protein vp1 | capsid protein vp1 | VIRUS LIKE PARTICLE | 05/02/18 | Cryo-EM structure of BK polyomavirus like particle in complex with single chain antibody ScFv41F17 | BK POLYOMAVIRUS; HOMO SAPIENS | homo sapiens | homo sapiens | bk polyomavirus | bk polyomavirus | Srinivas, H. | 4.24 | ELECTRON MICROSCOPY | null | null | false | true | IGHV4 | IGKV3 | Kappa | null | null | null | null | null |
3twc | H | L | 0 | H | Hapten | AML | AMYLAMINE | IMMUNE SYSTEM | 09/21/11 | Crystal structure of broad and potent HIV-1 neutralizing antibody PGT127 in complex with Man9 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Pejchal, R., Wilson, I.A. | 1.65 | X-RAY DIFFRACTION | 0.215 | 0.192 | false | true | IGHV4 | IGLV2 | Lambda | null | null | null | null | null |
2p47 | B | null | 0 | A | protein | null | ribonuclease pancreatic | HYDROLASE/IMMUNE SYSTEM | 03/11/07 | Complex of a camelid single-domain vhh antibody fragment with RNASE A at 2.5A resolution: SE5B-TRI crystal form with five se-met sites (L4M, M34, M51, F68M, M83) in vhh scaffold. | CAMELUS DROMEDARIUS; BOS TAURUS | camelus dromedarius | null | bos taurus | Tereshko, V., Uysal, S., Koide, A., Margalef, K., Koide, S., Kossiakoff, A.A. | 2.5 | X-RAY DIFFRACTION | 0.294 | 0.230 | false | true | IGHV1 | null | null | 0 | -9.61 | Other | 30 | 18445622 |
3chn | D | N | 9 | null | null | null | null | IMMUNE SYSTEM | 03/10/08 | Solution structure of human secretory IgA1 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Bonner, A., Almogren, A., Furtado, P.B., Kerr, M.A., Perkins, S.J. | NOT | SOLUTION SCATTERING / HOMOLOGY MODEL | null | null | false | false | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
7kn6 | H | L | 0 | A | protein | null | spike protein s1 | VIRAL PROTEIN/IMMUNE SYSTEM | 11/04/20 | Crystal structure of SARS-CoV-2 receptor binding domain complexed with nanobody VHH V and antibody Fab CC12.3 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; VICUGNA PACOS; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Liu, H., Yuan, M., Zhu, X., Wu, N.C., Wilson, I.A. | 2.55 | X-RAY DIFFRACTION | 0.239 | 0.193 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
7a50 | A | null | 0 | B | peptide | null | coiled-coil aph | DE NOVO PROTEIN | 08/20/20 | Crystal structure of the APH coiled-coil in complex with nanobody Nb26 | LAMA GLAMA; SYNTHETIC CONSTRUCT | lama glama | null | synthetic construct | Hadzi, S. | 1.999 | X-RAY DIFFRACTION | 0.226 | 0.182 | false | true | IGHV1 | null | null | null | null | null | null | null |
2kqm | null | B | 2 | null | null | null | null | IMMUNE SYSTEM | 11/11/09 | Solution structure of the KI O18/O8 Y87H immunoglobulin light chain variable domain | HOMO SAPIENS | null | homo sapiens | null | Volkman, B.F., Peterson, F.C., Ramirez-Alvarado, M., Baden, E.M. | NOT | SOLUTION NMR | null | null | false | true | null | IGKV1 | Kappa | null | null | null | null | null |
5mu0 | K | L | 0 | V | peptide | null | ia03 peptide containing the citrullinated c1 epitope ofcollagen type ii,collagen alpha-1(ii) chain,ia03 peptide containing the citrullinated c1 epitope of collagen type ii | IMMUNE SYSTEM | 01/11/17 | ACC1 Fab fragment in complex with citrullinated C1 epitope of CII (IA03) | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | mus musculus | Dobritzsch, D., Holmdahl, R., Ge, C. | 2.7 | X-RAY DIFFRACTION | 0.279 | 0.252 | false | false | IGHV6 | IGKV3 | Kappa | null | null | null | null | null |
7n0h | X | null | 0 | A | protein | null | spike glycoprotein | VIRAL PROTEIN | 05/25/21 | CryoEM structure of SARS-CoV-2 spike protein (S-6P, 2-up) in complex with sybodies (Sb45) | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; SYNTHETIC CONSTRUCT | synthetic construct | null | severe acute respiratory syndrome coronavirus2 | Jiang, J., Huang, R., Margulies, D. | 3.34 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
6jri | G | null | 0 | null | null | null | null | ANTIVIRAL PROTEIN | 04/04/19 | Crystal structure of Nanobody | VICUGNA PACOS | vicugna pacos | null | null | Mo, X., Li, J., Xu, X., Yuan, A.Y. | 3.101 | X-RAY DIFFRACTION | 0.259 | 0.235 | false | true | IGHV1 | null | null | null | null | null | null | null |
6x03 | C | null | 0 | null | null | null | null | STRUCTURAL PROTEIN | 05/15/20 | Nup84-Nup133 (aa521-1157) from S. cerevisiae bound by VHH-SAN8 and VHH-SAN9 | SACCHAROMYCES CEREVISIAE (STRAIN ATCC 204508 / S288C); VICUGNA PACOS | vicugna pacos | null | null | Nordeen, S.A., Schwartz, T.U. | 7.3 | X-RAY DIFFRACTION | 0.353 | 0.335 | false | true | IGHV1 | null | null | null | null | null | null | null |
6qd8 | W | Z | 0 | D | C | protein | protein | NA | NA | envelope glycoprotein | envelope glycoprotein,virion spike glycoprotein,ebov-gp1 | VIRAL PROTEIN | 01/01/19 | EM structure of a EBOV-GP bound to 4M0368 neutralizing antibody | HOMO SAPIENS; EBOLA VIRUS | homo sapiens | homo sapiens | ebola virus | ebola virus | Diskin, R., Cohen-Dvashi, H. | 3.3 | ELECTRON MICROSCOPY | null | null | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
4x4z | null | B | 0 | null | null | null | null | IMMUNE SYSTEM | 12/04/14 | Retrofitting antibodies with stabilizing mutations. Herceptin VL mutant F53D. | HOMO SAPIENS | null | homo sapiens | null | Langley, D.B., Rouet, R., Christ, D. | 1.8 | X-RAY DIFFRACTION | 0.213 | 0.177 | false | true | null | IGKV1 | Kappa | null | null | null | null | null |
3iet | B | A | 0 | X | peptide | null | podoplanin | IMMUNE SYSTEM | 07/23/09 | Crystal Structure of 237mAb with antigen | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Brooks, C.L., Evans, S.V., Borisova, S.N. | 2.2 | X-RAY DIFFRACTION | 0.271 | 0.227 | false | true | IGHV6 | IGKV1 | Kappa | 0 | -9.350354 | Unknown | null | TBD |
1yyl | R | Q | 0 | P | protein | null | exterior membrane glycoprotein(gp120) | Viral protein/Immune system | 02/25/05 | crystal structure of CD4M33, a scorpion-toxin mimic of CD4, in complex with HIV-1 YU2 gp120 envelope glycoprotein and anti-HIV-1 antibody 17b | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Huang, C.C., Stricher, F., Martin, L., Decker, J.M., Majeed, S., Barthe, P., Hendrickson, W.A., Robinson, J., Roumestand, C., Sodroski, J., Wyatt, R., Shaw, G.M., Vita, C., Kwong, P.D. | 2.75 | X-RAY DIFFRACTION | 0.275 | 0.202 | false | true | IGHV1 | IGKV3 | Kappa | 0 | -11.9 | ITC | 37 | 15893666 |
5ifa | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 02/25/16 | Crystal structure of unbound VRC01c-HuGL2 Fab from an HIV-1 naive donor at 1.82 A | HOMO SAPIENS | homo sapiens | homo sapiens | null | Sarkar, A., Wilson, I.A. | 1.821 | X-RAY DIFFRACTION | 0.240 | 0.205 | false | true | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
7rt9 | A | B | 0 | Y | peptide | null | peptide yy | HORMONE/IMMUNE SYSTEM | 08/12/21 | Crystal structures of human PYY and NPY | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | homo sapiens | Langley, D.B., Christ, D. | 1.9 | X-RAY DIFFRACTION | 0.213 | 0.179 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
7d7m | E | null | 0 | D | B | protein | protein | NA | NA | guanine nucleotide-binding protein g(s) subunit alphaisoforms short,guanine nucleotide-binding protein g(s) subunit alpha isoforms short,guanine nucleotide-binding protein g(s) subunit alpha isoforms short | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | MEMBRANE PROTEIN | 10/05/20 | Cryo-EM Structure of the Prostaglandin E Receptor EP4 Coupled to G Protein | HOMO SAPIENS; LAMA GLAMA | lama glama | null | homo sapiens | homo sapiens | Nojima, S., Fujita, Y., Kimura, T.K., Nomura, N., Suno, R., Morimoto, K., Yamamoto, M., Noda, T., Iwata, S., Shigematsu, H., Kobayashi, T. | 3.3 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | null | null | null | null | null | null | null |
4fqr | g | h | 0 | G | protein | null | broadly neutralizing antibody c05, heavy chain | VIRAL PROTEIN/IMMUNE SYSTEM | 06/25/12 | Crystal structure of broadly neutralizing antibody C05 bound to H3 influenza hemagglutinin | INFLUENZA A VIRUS; HOMO SAPIENS | homo sapiens | homo sapiens | influenza a virus | Ekiert, D.C., Wilson, I.A. | 4.1 | X-RAY DIFFRACTION | 0.334 | 0.309 | false | false | IGHV3 | IGKV1 | Kappa | 0 | -9.549709 | SPR | null | TBD |
6ute | C | D | 0 | S | protein | null | envelope domain iii | VIRAL PROTEIN | 10/29/19 | Crystal structure of Z032 Fab in complex with WNV EDIII | HOMO SAPIENS; WEST NILE VIRUS | homo sapiens | homo sapiens | west nile virus | Esswein, S.R., Gristick, H.B., Keeffe, J.R., Bjorkman, P.J. | 2.9 | X-RAY DIFFRACTION | 0.264 | 0.223 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
3sn6 | N | null | 0 | A | B | protein | protein | NA | NA | guanine nucleotide-binding protein g(s) subunit alphaisoforms short | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | SIGNALING PROTEIN/Hydrolase | 06/28/11 | Crystal structure of the beta2 adrenergic receptor-Gs protein complex | BOS TAURUS; ENTEROBACTERIA PHAGE T4, HOMO SAPIENS; LAMA GLAMA; RATTUS NORVEGICUS | lama glama | null | bos taurus | rattus norvegicus | Rasmussen, S.G.F., DeVree, B.T., Zou, Y., Kruse, A.C., Chung, K.Y., Kobilka, T.S., Thian, F.S., Chae, P.S., Pardon, E., Calinski, D., Mathiesen, J.M., Shah, S.T.A., Lyons, J.A., Caffrey, M., Gellman, S.H., Steyaert, J., Skiniotis, G., Weis, W.I., Sunahara, R.K., Kobilka, B.K. | 3.2 | X-RAY DIFFRACTION | 0.277 | 0.226 | false | true | IGHV1 | null | null | null | null | null | null | null |
6oro | J | K | 0 | I | protein | null | rc1 variant of hiv-1 env glycoprotein gp120 | VIRAL PROTEIN/Immune System | 04/30/19 | Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch antibody Ab874NHP | HUMAN IMMUNODEFICIENCY VIRUS 1; MACACA MULATTA | macaca mulatta | macaca mulatta | human immunodeficiency virus 1 | Abernathy, M.E., Gristick, H.B., Bjorkman, P.J. | 3.9 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGLV3 | Lambda | null | null | null | null | null |
5gs1 | E | e | 0 | null | null | null | null | IMMUNE SYSTEM | 08/13/16 | Crystal structure of homo-specific diabody | HOMO SAPIENS | homo sapiens | null | null | Kim, J.H., Song, D.H., Youn, S.J., Kim, J.W., Cho, G., Lee, H., Lee, J.O. | 2.0 | X-RAY DIFFRACTION | 0.286 | 0.267 | true | true | unknown | unknown | unknown | null | null | null | null | null |
6w4v | C | D | 0 | null | null | null | null | IMMUNE SYSTEM | 03/11/20 | Structure of anti-ferroportin Fab45D8 | MUS MUSCULUS | mus musculus | mus musculus | null | Billesboelle, C.B., Azumaya, C.M., Gonen, S., Powers, A., Kretsch, R.C., Schneider, S., Arvedson, T., Dror, R.O., Cheng, Y., Manglik, A. | 2.1 | X-RAY DIFFRACTION | 0.247 | 0.216 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
1p7k | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 05/02/03 | Crystal structure of an anti-ssDNA antigen-binding fragment (Fab) bound to 4-(2-Hydroxyethyl)piperazine-1-ethanesulfonic acid (HEPES) | MUS MUSCULUS | mus musculus | mus musculus | null | Schuermann, J.P., Henzl, M.T., Deutscher, S.L., Tanner, J.J. | 1.75 | X-RAY DIFFRACTION | 0.230 | 0.197 | false | true | IGHV1 | IGKV12 | Kappa | null | null | null | null | null |
6ey6 | N | null | 0 | F | protein | null | t9ss component cytoplasmic membrane protein porm | PROTEIN TRANSPORT | 11/10/17 | C-terminal part (residues 315-516) of PorM with the llama naobody nb130 | PORPHYROMONAS GINGIVALIS; LAMA GLAMA | lama glama | null | porphyromonas gingivalis | Leone, P., Cambillau, C., Roussel, A. | 2.1 | X-RAY DIFFRACTION | 0.215 | 0.181 | false | true | IGHV1 | null | null | null | null | null | null | null |
7m53 | H | L | 0 | A | peptide | null | spike glycoprotein stem helix peptide | ANTIVIRAL PROTEIN, IMMUNE SYSTEM | 03/22/21 | B6 Fab fragment bound to the SARS-CoV/-2 spike stem helix peptide | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | severe acute respiratory syndrome coronavirus2 | Sauer, M.M., Park, Y.J., Veesler, D., Center for Structural Genomics of Infectious Diseases (CSGID), Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 1.4 | X-RAY DIFFRACTION | 0.174 | 0.144 | false | true | IGHV1 | IGKV8 | Kappa | null | null | null | null | null |
7luc | J | K | 0 | A | protein | null | fusion glycoprotein f0 | IMMUNE SYSTEM/VIRAL PROTEIN | 02/22/21 | Cryo-EM structure of RSV preF bound by Fabs 32.4K and 01.4B | RESPIRATORY SYNCYTIAL VIRUS; HOMO SAPIENS | homo sapiens | homo sapiens | respiratory syncytial virus | Wrapp, D., McLellan, J.S. | 3.21 | ELECTRON MICROSCOPY | null | null | false | true | IGHV5 | IGKV1 | Kappa | null | null | null | null | null |
7mji | E | null | 0 | B | protein | null | spike glycoprotein | Viral Protein/Immune System | 04/20/21 | Cryo-EM structure of the SARS-CoV-2 N501Y mutant spike protein ectodomain bound to VH ab8 (focused refinement of RBD and VH ab8) | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; SYNTHETIC CONSTRUCT | synthetic construct | null | severe acute respiratory syndrome coronavirus2 | Zhu, X., Mannar, D., Srivastava, S.S., Berezuk, A.M., Demers, J.P., Saville, J.W., Leopold, K., Li, W., Dimitrov, D.S., Tuttle, K.S., Zhou, S., Chittori, S., Subramaniam, S. | 2.81 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | null | null | null | null | null | null | null |
3b2u | J | K | 0 | I | protein | null | epidermal growth factor receptor | IMMUNE SYSTEM/TRANSFERASE | 10/19/07 | Crystal structure of isolated domain III of the extracellular region of the epidermal growth factor receptor in complex with the Fab fragment of IMC-11F8 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Ferguson, K.M., Li, S., Kussie, P. | 2.58 | X-RAY DIFFRACTION | 0.291 | 0.227 | false | true | IGHV4 | IGKV3 | Kappa | 0 | -12.27 | SPR | 25 | 18275813 |
3zlq | D | null | 0 | B | protein | null | beta-secretase 2 | HYDROLASE/IMMUNE SYSTEM | 02/04/13 | BACE2 XAPERONE COMPLEX | HOMO SAPIENS; LAMA GLAMA | lama glama | null | homo sapiens | Kuglstatter, A., Stihle, M. | 2.1 | X-RAY DIFFRACTION | 0.29601 | 0.23825 | false | true | IGHV3 | null | null | null | null | null | null | null |
6rlo | E | F | 0 | K | protein | null | cd9 antigen | IMMUNE SYSTEM | 05/02/19 | Crystal structure of AT1412dm Fab fragment in complex with CD9 large extracellular loop | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Neviani, V., Pearce, N.M., Pos, W., Schotte, R., Spits, H., Gros, P. | 2.2 | X-RAY DIFFRACTION | 0.287 | 0.254 | false | true | IGHV3 | IGKV4 | Kappa | null | null | null | null | null |
6tco | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 11/06/19 | Crystal structure of the omalizumab Fab Leu158Pro light chain mutant - crystal form I | HOMO SAPIENS | homo sapiens | homo sapiens | null | Mitropoulou, A.N., Ceska, T., Beavil, A.J., Henry, A.J., McDonnell, J.M., Sutton, B.J., Davies, A.M. | 1.8 | X-RAY DIFFRACTION | 0.192 | 0.168 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
3idy | H | L | 0 | G | protein | null | hiv-1 hxbc2 gp120 core | IMMUNE SYSTEM | 07/22/09 | Crystal structure of HIV-gp120 core in complex with CD4-binding site antibody b13, space group C2221 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Chen, L., Kwon, Y.D., Zhou, T., Wu, X., O'Dell, S., Cavacini, L., Hessell, A.J., Pancera, M., Tang, M., Xu, L., Yang, Z.Y., Zhang, M.Y., Arthos, J., Burton, D.R., Dimitrov, D.S., Nabel, G.J., Posner, M., Sodroski, J., Wyatt, R., Mascola, J.R., Kwong, P.D. | 3.2 | X-RAY DIFFRACTION | 0.237 | 0.196 | false | true | IGHV3 | IGKV1 | Kappa | 0 | -11.450945 | SPR | null | TBD |
7lzp | G | null | 0 | A | protein | null | botulinum neurotoxin a light chain | ANTITOXIN | 03/10/21 | LC/A-JPU-B9-JPU-A11-JPU-G11 | CLOSTRIDIUM BOTULINUM; VICUGNA PACOS | vicugna pacos | null | clostridium botulinum | Lam, K., Jin, R. | 2.86 | X-RAY DIFFRACTION | 0.273 | 0.235 | false | true | unknown | unknown | unknown | null | null | null | null | null |
5lcv | H | L | 0 | A | B | protein | protein | NA | NA | polyprotein | polyprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 06/22/16 | Structural basis of Zika and Dengue virus potent antibody cross-neutralization | ZIKA VIRUS; HOMO SAPIENS | homo sapiens | homo sapiens | zika virus | zika virus | Barba-Spaeth, G. | 2.64 | X-RAY DIFFRACTION | 0.237 | 0.224 | false | true | IGHV3 | IGLV2 | Lambda | 0.000001 | -8.288766 | BLI | null | TBD |
2a9m | I | M | 0 | null | null | null | null | IMMUNE SYSTEM | 07/12/05 | Structural Analysis of a Tight-binding Fluorescein-scFv; apo form | HOMO SAPIENS | homo sapiens | homo sapiens | null | Cambillau, C., Spinelli, S., Honegger, A., Pluckthun, A. | 2.1 | X-RAY DIFFRACTION | 0.263 | 0.210 | true | true | IGHV3 | IGLV1 | Lambda | null | null | null | null | null |
7cky | N | null | 0 | A | B | G | protein | protein | protein | NA | NA | NA | guanine nucleotide-binding protein g(s) subunit alphaisoforms short | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | guanine nucleotide-binding protein g(i)/g(s)/g(o) subunitgamma-2 | CELL CYCLE | 07/20/20 | Cryo-EM structure of PW0464 bound dopamine receptor DRD1-Gs signaling complex | HOMO SAPIENS; LAMA GLAMA | lama glama | null | homo sapiens | homo sapiens | homo sapiens | Yan, W., Shao, Z. | 3.2 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | null | null | null | null | null | null | null |
3bd4 | null | B | 0 | null | null | null | null | IMMUNE SYSTEM | 11/14/07 | Crystal structure of single domain VL of an anti-DNA binding antibody 3D8 scFv and its active site revealed by complex structures of a small molecule and metals | MUS MUSCULUS | null | mus musculus | null | Park, S.K., Kim, J.S. | 2.4 | X-RAY DIFFRACTION | 0.281 | 0.213 | true | true | null | IGKV8 | Kappa | null | null | null | null | null |
7n8q | C | D | 0 | A | protein | null | clade a/e 93th057 hiv-1 gp120 core | IMMUNE SYSTEM | 06/15/21 | Rhesusized RV305 DH677.3 Fab bound to Clade A/E 93TH057 HIV-1 gp120 core. | HUMAN IMMUNODEFICIENCY VIRUS 1; MACACA MULATTA; SYNTHETIC CONSTRUCT | macaca mulatta | macaca mulatta | human immunodeficiency virus 1 | Tolbert, W.D., Pazgier, M. | 2.9 | X-RAY DIFFRACTION | 0.296 | 0.255 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
6vvu | H | L | 0 | A | protein | null | tryptase alpha/beta-1 | HYDROLASE/IMMUNE SYSTEM | 02/18/20 | Anti-Tryptase fab E104.v1 bound to tryptase | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Ultsch, M., Koerber, J.T. | 3.0 | X-RAY DIFFRACTION | 0.232 | 0.187 | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
3gbn | H | L | 0 | B | A | protein | protein | NA | NA | hemagglutinin | hemagglutinin | VIRAL PROTEIN/IMMUNE SYSTEM | 02/20/09 | Crystal Structure of Fab CR6261 in Complex with the 1918 H1N1 influenza virus hemagglutinin | INFLUENZA A VIRUS (A/BREVIG MISSION/1/1918(H1N1)); HOMO SAPIENS | homo sapiens | homo sapiens | influenza a virus (a/brevigmission/1/1918(h1n1)) | influenza a virus (a/brevigmission/1/1918(h1n1)) | Ekiert, D.C., Elsliger, M.A., Wilson, I.A. | 2.2 | X-RAY DIFFRACTION | 0.241 | 0.205 | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
6mph | f | h | 0 | A | protein | null | pgt122 light chain | VIRAL PROTEIN | 10/06/18 | Cryo-EM structure at 3.8 A resolution of HIV-1 fusion peptide-directed antibody, DF1W-a.01, elicited by vaccination of Rhesus macaques, in complex with stabilized HIV-1 Env BG505 DS-SOSIP, which was also bound to antibodies VRC03 and PGT122 | MACACA MULATTA; HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Acharya, P., Xu, K., Kwong, P.D. | 3.8 | ELECTRON MICROSCOPY | null | null | false | false | unknown | IGKV3 | Kappa | null | null | null | null | null |
6lz2 | B | null | 0 | A | protein | null | thermostable green fluorescent protein | FLUORESCENT PROTEIN | 02/17/20 | Crystal structure of a thermostable green fluorescent protein (TGP) with a synthetic nanobody (Sb44) | GALAXEA FASCICULARIS; LAMA GLAMA | lama glama | null | galaxea fascicularis | Cai, H., Yao, H., Li, T., Hutter, C., Tang, Y., Li, Y., Seeger, M., Li, D. | 2.03 | X-RAY DIFFRACTION | 0.215 | 0.175 | false | true | IGHV1 | null | null | null | null | null | null | null |
6u38 | H | L | 0 | B | protein | null | proprotein convertase subtilisin/kexin type 9 | HYDROLASE/Immune System | 08/21/19 | PCSK9 in complex with a Fab and compound 8 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Lu, J., Soisson, S. | 2.73 | X-RAY DIFFRACTION | 0.243 | 0.227 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
6okp | M | N | 0 | D | protein | null | envelope glycoprotein gp120 | VIRAL PROTEIN/IMMUNE SYSTEM | 04/14/19 | B41 SOSIP.664 in complex with the silent-face antibody SF12 and V3-targeting antibody 10-1074 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Barnes, C.O., Bjorkman, P.J. | 3.28 | ELECTRON MICROSCOPY | null | null | false | true | IGHV4 | IGKV3 | Kappa | null | null | null | null | null |
6n5d | E | F | 0 | B | protein | null | hemagglutinin | VIRAL PROTEIN/IMMUNE SYSTEM | 11/21/18 | Broadly protective antibodies directed to a subdominant influenza hemagglutinin epitope | INFLUENZA A VIRUS; MUS MUSCULUS | mus musculus | mus musculus | influenza a virus | Bajic, G., Schmidt, A.G. | 3.0 | X-RAY DIFFRACTION | 0.244 | 0.217 | false | true | IGHV5 | IGLV1 | Lambda | null | null | null | null | null |
6qno | H | L | 0 | A | B | G | protein | protein | peptide | NA | NA | NA | guanine nucleotide-binding protein g(i) subunit alpha-1 | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | guanine nucleotide-binding protein g(t) subunit gamma-t1 | SIGNALING PROTEIN | 02/11/19 | Rhodopsin-Gi protein complex | HOMO SAPIENS; MUS MUSCULUS; BOS TAURUS | mus musculus | mus musculus | homo sapiens | bos taurus | bos taurus | Tsai, C.-J., Marino, J., Adaixo, R.J., Pamula, F., Muehle, J., Maeda, S., Flock, T., Taylor, N.M.I., Mohammed, I., Matile, H., Dawson, R.J.P., Deupi, X., Stahlberg, H., Schertler, G.F.X. | 4.38 | ELECTRON MICROSCOPY | null | null | false | true | IGHV5 | IGKV2 | Kappa | null | null | null | null | null |
4m61 | D | C | 0 | null | null | null | null | IMMUNE SYSTEM | 08/08/13 | Crystal structure of unliganded anti-DNA Fab A52 | MUS MUSCULUS | mus musculus | mus musculus | null | Stanfield, R.L., Eilat, D., Wilson, I.A. | 1.62 | X-RAY DIFFRACTION | 0.232 | 0.192 | false | false | IGHV1 | IGKV8 | Kappa | null | null | null | null | null |
6e62 | B | C | 0 | A | protein | null | pf48/45 | IMMUNE SYSTEM | 07/23/18 | Crystal structure of malaria transmission-blocking antigen Pfs48/45 6C in complex with antibody 85RF45.1 | PLASMODIUM FALCIPARUM; RATTUS NORVEGICUS | rattus norvegicus | rattus norvegicus | plasmodium falciparum | Kundu, P., Semesi, A., Julien, J.P. | 2.7 | X-RAY DIFFRACTION | 0.276 | 0.246 | false | true | IGHV5 | IGLV3 | Lambda | 0 | -11.589049 | SPR | null | TBD |
4kk9 | C | D | 0 | A | protein | null | h(+)/cl(-) exchange transporter clca | TRANSPORT PROTEIN | 05/05/13 | Structure of the E148A mutant of CLC-ec1 deltaNC construct in 100mM fluoride and 2mM Bromide | ESCHERICHIA COLI; MUS MUSCULUS | mus musculus | mus musculus | escherichia coli | Lim, H.-H., Miller, C. | 2.997 | X-RAY DIFFRACTION | 0.270 | 0.217 | false | true | IGHV4 | IGKV4 | Kappa | null | null | null | null | null |
6b5o | H | L | 0 | A | peptide | null | pfcsp peptide 29 | IMMUNE SYSTEM | 09/29/17 | Structure of PfCSP peptide 29 with human protective antibody CIS43 | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | plasmodium falciparum | Pancera, M., Weidle, C. | 2.194 | X-RAY DIFFRACTION | 0.240 | 0.193 | false | true | IGHV1 | IGKV4 | Kappa | 0 | -11.366355 | Unknown | null | TBD |
7x6l | H | L | 0 | F | C | protein | protein | NA | NA | hemagglutinin | hemagglutinin | STRUCTURAL PROTEIN | 03/07/22 | Cryo-EM structure of H3 hemagglutinin from A/HongKong/01/1968 in complex with a neutralizing antibody 28-12 | HOMO SAPIENS; INFLUENZA A VIRUS (A/HONG KONG/1/1968(H3N2)); INFLUENZA A VIRUS | homo sapiens | homo sapiens | influenza a virus | influenza a virus (a/hong kong/1/1968(h3n2)) | Cong, Y., Liu, C.X. | 3.7 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6b5n | H | L | 0 | A | peptide | null | pfcsp peptide 25asp | IMMUNE SYSTEM | 09/29/17 | Structure of PfCSP peptide 25 with human protective antibody CIS43 | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | plasmodium falciparum | Pancera, M., Weidle, C. | 1.98 | X-RAY DIFFRACTION | 0.209 | 0.175 | false | true | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
6rlm | E | F | 0 | null | null | null | null | IMMUNE SYSTEM | 05/02/19 | Crystal structure of AT1412dm Fab fragment | HOMO SAPIENS | homo sapiens | homo sapiens | null | Neviani, V., Pearce, N.M., Pos, W., Schotte, R., Spits, H., Gros, P. | 2.5 | X-RAY DIFFRACTION | 0.267 | 0.242 | false | true | IGHV3 | IGKV4 | Kappa | null | null | null | null | null |
6ss2 | H | L | 0 | A | protein | null | unknown | PROTEIN BINDING | 09/06/19 | Structure of arginase-2 in complex with the inhibitory human antigen-binding fragment Fab C0021158 | HOMO SAPIENS | null | null | null | Burschowsky, D., Addyman, A., Fiedler, S., Groves, M., Haynes, S., Seewooruthun, C., Carr, M. | 2.4 | X-RAY DIFFRACTION | 0.284 | 0.254 | false | false | IGHV3 | IGLV1 | Lambda | null | null | null | null | null |
7rth | e | null | 0 | null | null | null | null | IMMUNE SYSTEM | 08/13/21 | Crystal structure of an anti-lysozyme nanobody in complex with an anti-nanobody Fab ""NabFab"" | HOMO SAPIENS | homo sapiens | null | null | Filippova, E.V., Mukherjee, S., Bloch, J.S., Locher, K.P., Kossiakoff, A.A. | 3.19 | X-RAY DIFFRACTION | 0.267 | 0.216 | false | false | IGHV1 | null | null | null | null | null | null | null |
6j5g | H | L | 0 | A | protein | null | envelope protein e | VIRAL PROTEIN/IMMUNE SYSTEM | 01/10/19 | Complex structure of MAb 4.2-scFv with tick-borne encephalitis virus envelope protein | TICK-BORNE ENCEPHALITIS VIRUS EUROPEAN SUBTYPE (STRAIN NEUDOERFL); MUS MUSCULUS | mus musculus | mus musculus | tick-borne encephalitis virus european subtype(strain neudoerfl) | Yang, X., Qi, J., Peng, R., Dai, L., Gould, E.A., Tien, P., Gao, G.F. | 3.291 | X-RAY DIFFRACTION | 0.222 | 0.208 | false | true | IGHV1 | IGKV12 | Kappa | null | null | null | null | null |
5ywp | N | M | 0 | C | protein | null | jev e protein | IMMUNE SYSTEM | 11/29/17 | JEV-2H4 Fab complex | JAPANESE ENCEPHALITIS VIRUS; MUS MUSCULUS | mus musculus | mus musculus | japanese encephalitis virus | Qiu, X.D., Lei, Y.F., Yang, P., Gao, Q., WANG, N., Cao, L., Yuan, S., Wang, X.X., Xu, Z.K., Rao, Z.H. | 4.6 | ELECTRON MICROSCOPY | null | null | false | false | IGHV9 | IGKV3 | Kappa | null | null | null | null | null |
5tbd | D | G | 0 | H | peptide | null | merozoite surface protein 2 | IMMUNE SYSTEM | 09/12/16 | Crystal Structure of anti-MSP2 Fv fragment (mAb4D11) in complex with 3D7-MSP2 215-222 | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | plasmodium falciparum 3d7 | Seow, J., Morales, R.A.V., MacRaild, C.A., Bankala, K., Drinkwater, N., Dingjan, T., Jaipuria, G., Wilde, K., Anders, R.F., Atreya, H.S., Christ, D., McGowan, S., Norton, R.S. | 2.2 | X-RAY DIFFRACTION | 0.247 | 0.207 | false | true | IGHV14 | IGKV1 | Kappa | null | null | null | null | null |
5xmh | D | C | 0 | B | protein | null | immunoglobulin gamma-1 heavy chain | IMMUNE SYSTEM | 05/15/17 | Crystal structure of an IgM rheumatoid factor YES8c in complex with IgG1 Fc | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Shiroishi, M., Shimokawa, K., Lee, J.M., Kusakabe, M., Ueda, T. | 2.8 | X-RAY DIFFRACTION | 0.272 | 0.220 | false | true | IGHV1 | IGKV3 | Kappa | 0.00016 | -5.178507 | SPR | null | TBD |
7m42 | D | C | 0 | E | protein | null | spike protein s1 | VIRAL PROTEIN/IMMUNE SYSTEM | 03/19/21 | Complex of SARS-CoV-2 receptor binding domain with the Fab fragments of neutralizing antibodies REGN10985 and REGN10989 | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Zhou, Y., Romero Hernandez, A., Saotome, K., Franklin, M.C. | 3.3 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGLV1 | Lambda | null | null | null | null | null |
6m87 | F | E | 0 | E | Hapten | 2M9 | 8-methoxypyrene-1,3,6-trisulfonic acid | IMMUNE SYSTEM | 08/21/18 | Fab 10A6 in complex with MPTS | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Stanfield, R.L., Wilson, I.A. | 2.609 | X-RAY DIFFRACTION | 0.265 | 0.228 | false | false | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
4unt | null | H | 0 | null | null | null | null | IMMUNE SYSTEM | 05/30/14 | Induced monomer of the Mcg variable domain | HOMO SAPIENS | null | homo sapiens | null | Brumshtein, B., Esswein, S.R., Landau, M., Ryan, C.M., Whitelegge, J.P., Phillips, M.L., Cascio, D., Sawaya, M.R., Eisenberg, D.S. | 2.7 | X-RAY DIFFRACTION | 0.28925 | 0.24328 | false | true | null | IGLV2 | Lambda | null | null | null | null | null |
7ejx | S | s | 0 | A | B | protein | protein | NA | NA | guanine nucleotide-binding protein g(i) subunit alpha-1 | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | MEMBRANE PROTEIN | 04/02/21 | Structure of the GPR88-Gi1 signaling complex bound to a synthetic ligand | HOMO SAPIENS; MUS MUSCULUS | mus musculus | null | homo sapiens | homo sapiens | Xu, J., Chen, G., Liu, Z., Du, Y. | 2.4 | ELECTRON MICROSCOPY | null | null | true | true | unknown | unknown | unknown | null | null | null | null | null |
6jri | B | null | 0 | null | null | null | null | ANTIVIRAL PROTEIN | 04/04/19 | Crystal structure of Nanobody | VICUGNA PACOS | vicugna pacos | null | null | Mo, X., Li, J., Xu, X., Yuan, A.Y. | 3.101 | X-RAY DIFFRACTION | 0.259 | 0.235 | false | true | IGHV1 | null | null | null | null | null | null | null |
4uta | I | M | 0 | A | protein | null | envelope glycoprotein e | IMMUNE SYSTEM-VIRAL PROTEIN COMPLEX | 07/18/14 | Crystal structure of dengue 2 virus envelope glycoprotein in complex with the Fab fragment of the broadly neutralizing human antibody EDE1 C8 | HOMO SAPIENS; DENGUE VIRUS 2 | homo sapiens | homo sapiens | dengue virus 2 | Rouvinski, A., Guardado-Calvo, P., Barba-Spaeth, G., Duquerroy, S., Vaney, M.C., Rey, F.A. | 3.0 | X-RAY DIFFRACTION | 0.2477 | 0.2128 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
6qgy | D | null | 0 | C | protein | null | outer membrane protein assembly factor bama | MEMBRANE PROTEIN | 01/14/19 | Crystal structure of E.coli BamA beta-barrel in complex with nanobody B12 | ESCHERICHIA COLI O157:H7; LAMA GLAMA | lama glama | null | escherichia coli o157 | Hartmann, J.-B., Kaur, H., Jakob, R.P., Zahn, M., Zimmermann, I., Seeger, M., Maier, T., Hiller, S. | 2.509 | X-RAY DIFFRACTION | 0.244 | 0.222 | false | true | IGHV1 | null | null | null | null | null | null | null |
7d5b | D | null | 0 | A | protein | null | beta-secretase 2 | HYDROLASE/IMMUNE SYSTEM | 09/25/20 | BACE2 xaperone complex with N-{3-[(5R)-3-amino-2,5-dimethyl-1,1-dioxo-5,6-dihydro-2H-1lambda6,2,4-thiadiazin-5-yl]-4-fluorophenyl}-5-fluoropyridine-2-carboxamide | HOMO SAPIENS | homo sapiens | null | homo sapiens | Fujimoto, K., Yoshida, S., Tadano, G., Asada, N., Fuchino, K., Suzuki, S., Matsuoka, E., Yamamoto, T., Yamamoto, S., Ando, S., Kanegawa, N., Tonomura, Y., Ito, H., Moechars, D., Rombouts, F.J.R., Gijsen, H.J.M., Kusakabe, K.I. | 1.31 | X-RAY DIFFRACTION | 0.222 | 0.195 | false | true | IGHV3 | null | null | null | null | null | null | null |
6x9t | H | L | 0 | A | B | protein | protein | NA | NA | hiv-1 envelope glycoprotein bg505 sosip.664 gp120 | hiv-1 envelope glycoprotein bg505 sosip.664 gp41 | VIRAL PROTEIN/IMMUNE SYSTEM | 06/03/20 | HIV-1 Envelope Glycoprotein BG505 SOSIP.664 expressed in HEK293S cells in complex with RM20A3 Fab | HUMAN IMMUNODEFICIENCY VIRUS 1; MACACA MULATTA | macaca mulatta | macaca mulatta | human immunodeficiency virus 1 | human immunodeficiency virus 1 | Berndsen, Z.T., Ward, A.B. | 3.2 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGLV2 | Lambda | null | null | null | null | null |
2aab | H | L | 0 | null | null | null | null | immune system | 07/13/05 | Structural basis of antigen mimicry in a clinically relevant melanoma antigen system | MUS MUSCULUS | mus musculus | mus musculus | null | Chang, C.-C., Hernandez-Guzman, F.G., Luo, W., Wang, X., Ferrone, S., Ghosh, D. | 2.5 | X-RAY DIFFRACTION | 0.297 | 0.236 | false | false | IGHV5 | IGKV3 | Kappa | null | null | null | null | null |
7ra3 | N | null | 0 | B | protein | null | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | MEMBRANE PROTEIN | 06/29/21 | cryo-EM of human Gastric inhibitory polypeptide receptor GIPR bound to GIP | HOMO SAPIENS; MUS MUSCULUS; LAMA GLAMA; SYNTHETIC CONSTRUCT | lama glama | null | homo sapiens | Sun, B., Kobilka, B.K., Sloop, K.W., Feng, D., Kobilka, T.S. | 3.24 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | null | null | null | null | null | null | null |
5t93 | null | C | 0 | null | null | null | null | IMMUNE SYSTEM | 09/09/16 | Immunoglobulin light chain variable domain AL-T05 | HOMO SAPIENS | null | homo sapiens | null | Ramirez-Alvarado, M., Blancas-Mejia, L.M. | 1.9 | X-RAY DIFFRACTION | 0.223 | 0.171 | false | true | null | IGLV1 | Lambda | null | null | null | null | null |
1bre | null | B | 0 | null | null | null | null | IMMUNOGLOBULIN | 07/19/95 | IMMUNOGLOBULIN LIGHT CHAIN PROTEIN | HOMO SAPIENS | null | homo sapiens | null | Schormann, N., Benson, M.D. | 2.0 | X-RAY DIFFRACTION | 0.337 | 0.218 | false | true | null | IGKV1 | Kappa | null | null | null | null | null |
3chn | B | M | 6 | null | null | null | null | IMMUNE SYSTEM | 03/10/08 | Solution structure of human secretory IgA1 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Bonner, A., Almogren, A., Furtado, P.B., Kerr, M.A., Perkins, S.J. | NOT | SOLUTION SCATTERING / HOMOLOGY MODEL | null | null | false | false | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
7ttm | H | L | 0 | A | protein | null | spike protein s1 | VIRAL PROTEIN/IMMUNE SYSTEM | 02/01/22 | Crystal structure of potent neutralizing antibody 10-40 in complex with Sarbecovirus bat SHC014 receptor-binding domain | BAT SARS-LIKE CORONAVIRUS RSSHC014; HOMO SAPIENS | homo sapiens | homo sapiens | bat sars-like coronavirus rsshc014 | Reddem, E.R., Shapiro, L. | 2.24 | X-RAY DIFFRACTION | 0.256 | 0.201 | false | true | IGHV4 | IGLV6 | Lambda | null | null | null | null | null |
3b2u | N | O | 0 | M | protein | null | epidermal growth factor receptor | IMMUNE SYSTEM/TRANSFERASE | 10/19/07 | Crystal structure of isolated domain III of the extracellular region of the epidermal growth factor receptor in complex with the Fab fragment of IMC-11F8 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Ferguson, K.M., Li, S., Kussie, P. | 2.58 | X-RAY DIFFRACTION | 0.291 | 0.227 | false | true | IGHV4 | IGKV3 | Kappa | 0 | -12.27 | SPR | 25 | 18275813 |
7lkh | H | L | 0 | A | protein | null | sterol regulatory element-binding protein cleavage-activating protein | LIPID BINDING PROTEIN | 02/02/21 | Chicken Scap D435V L1-L7 domain / Fab complex focused map | GALLUS GALLUS; MUS MUSCULUS | mus musculus | mus musculus | gallus gallus | Kober, D.L., Radhakrishnan, A., Goldstein, J.L., Brown, M.S., Clark, L.D., Bai, X.-C., Rosenbaum, D.M. | 3.5 | ELECTRON MICROSCOPY | null | null | false | false | IGHV14 | IGKV10 | Kappa | null | null | null | null | null |
4lgp | B | null | 0 | A | protein | null | ricin | HYDROLASE/IMMUNE SYSTEM | 06/28/13 | Ricin A chain bound to camelid nanobody (VHH1) | RICINUS COMMUNIS; VICUGNA PACOS | vicugna pacos | null | ricinus communis | Rudolph, M.J., Cheung, J., Franklin, M., Burshteyn, F., Cassidy, M., Gary, E., Mantis, N. | 2.4 | X-RAY DIFFRACTION | 0.281 | 0.225 | false | true | IGHV1 | null | null | null | null | null | null | null |
1vhp | A | null | 1 | null | null | null | null | IMMUNOGLOBULIN | 04/16/96 | VH-P8, NMR | HOMO SAPIENS | homo sapiens | null | null | Riechmann, L. | NOT | SOLUTION NMR | null | null | false | true | unknown | unknown | unknown | null | null | null | null | null |
1pkq | G | F | 0 | J | protein | null | myelin oligodendrocyte glycoprotein | IMMUNE SYSTEM | 06/06/03 | Myelin Oligodendrocyte Glycoprotein-(8-18C5) Fab-complex | MUS MUSCULUS; RATTUS NORVEGICUS | mus musculus | mus musculus | rattus norvegicus | Breithaupt, C., Schubart, A., Zander, H., Skerra, A., Huber, R., Linington, C., Jacob, U. | 3.0 | X-RAY DIFFRACTION | 0.319 | 0.250 | false | true | IGHV1 | IGKV8 | Kappa | null | null | null | null | null |
7s13 | H | L | 0 | D | protein | null | t-cell surface protein tactile | IMMUNE SYSTEM | 08/31/21 | Crystal structure of Fab in complex with mouse CD96 dimer | RATTUS; MUS MUSCULUS | rattus | rattus | mus musculus | Lee, P.S., Barman, I., Strop, P. | 2.12 | X-RAY DIFFRACTION | 0.265 | 0.217 | false | true | IGHV2 | IGLV3 | Lambda | null | null | null | null | null |
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