pdb stringlengths 4 4 | Hchain stringclasses 59
values | Lchain stringclasses 60
values | model int64 0 76 | antigen_chain stringclasses 386
values | antigen_type stringclasses 24
values | antigen_het_name stringclasses 240
values | antigen_name stringlengths 1 396 ⌀ | short_header stringclasses 448
values | date stringlengths 8 8 | compound stringlengths 4 243 | organism stringlengths 3 175 ⌀ | heavy_species stringclasses 121
values | light_species stringclasses 67
values | antigen_species stringclasses 937
values | authors stringlengths 6 762 | resolution stringlengths 1 8 | method stringclasses 10
values | r_free stringclasses 354
values | r_factor stringclasses 342
values | scfv bool 2
classes | engineered bool 2
classes | heavy_subclass stringclasses 14
values | light_subclass stringclasses 35
values | light_ctype stringclasses 3
values | affinity float64 0 0 ⌀ | delta_g float64 -16.91 -5.04 ⌀ | affinity_method stringclasses 11
values | temperature float64 4 37 ⌀ | pmid stringclasses 157
values |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
7m7j | E | F | 0 | B | protein | null | eryai | BIOSYNTHETIC PROTEIN/IMMUNE SYSTEM | 03/28/21 | 6-Deoxyerythronolide B synthase (DEBS) module 1 in complex with antibody fragment 1B2: ""turnstile closed"" state (TE-free) | SACCHAROPOLYSPORA ERYTHRAEA; HOMO SAPIENS | homo sapiens | homo sapiens | saccharopolyspora erythraea | Cogan, D.P., Zhang, K., Chiu, W., Khosla, C. | 4.3 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV2 | Kappa | null | null | null | null | null |
3gbm | I | M | 0 | D | C | protein | protein | NA | NA | hemagglutinin | hemagglutinin | viral protein / immune system | 02/20/09 | Crystal Structure of Fab CR6261 in Complex with a H5N1 influenza virus hemagglutinin. | INFLUENZA A VIRUS (A/VIET NAM/1203/2004(H5N1)); HOMO SAPIENS | homo sapiens | homo sapiens | influenza a virus (a/viet nam/1203/2004(h5n1)) | influenza a virus (a/viet nam/1203/2004(h5n1)) | Ekiert, D.C., Elsliger, M.A., Wilson, I.A. | 2.7 | X-RAY DIFFRACTION | 0.261 | 0.203 | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
6vn1 | H | L | 0 | A | protein | null | envelope glycoprotein b | VIRAL PROTEIN/IMMUNE SYSTEM | 01/29/20 | A 2.8 Angstrom Cryo-EM Structure of a Glycoprotein B-Neutralizing Antibody Complex Reveals a Critical Domain for Herpesvirus Fusion Initiation | HOMO SAPIENS; HUMAN ALPHAHERPESVIRUS 3 | homo sapiens | homo sapiens | human alphaherpesvirus 3 | Oliver, S.L. | 2.8 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
3mly | I | M | 0 | Q | peptide | null | hiv-1 gp120 third variable region (v3) crown | IMMUNE SYSTEM | 04/18/10 | Crystal structure of anti-HIV-1 V3 Fab 3074 in complex with a UR29 V3 peptide | HOMO SAPIENS; HUMAN IMMUNODEFICIENCY VIRUS 1 | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Kong, X.-P. | 1.7 | X-RAY DIFFRACTION | 0.215 | 0.181 | false | false | IGHV4 | IGLV1 | Lambda | null | null | null | null | null |
6snc | H | L | 0 | P | peptide | null | envelope glycoprotein gp160 | IMMUNE SYSTEM | 08/23/19 | crystal structure of LN01 Fab in complex with an HIV-1 gp41 peptide | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Caillat, C., Pinto, D., Corti, D., Fenwick, C., Pantaleo, G., Weissenhorn, W. | 3.2 | X-RAY DIFFRACTION | 0.254 | 0.213 | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
7bua | J | K | 0 | C | protein | null | genome polyprotein | VIRUS | 05/13/20 | Cryo-EM structure of zika virus complexed with Fab SIgN-3C at pH 8.0 | HOMO SAPIENS; ZIKA VIRUS ZIKV/H. SAPIENS/FRENCHPOLYNESIA/10087PF/2013 | homo sapiens | homo sapiens | zika virus zikv/h.sapiens/frenchpolynesia/10087pf/2013 | Zhang, S., Chew, S.V., Lim, X.N., Ng, T.S., Kostyuchenko, V.A., Lok, S.M. | 4.8 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
6o9i | A | B | 0 | C | protein | null | ecd | IMMUNE SYSTEM | 03/13/19 | Ternary complex of mouse ECD with Fab1 and Fab2 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Min, X., Wang, Z. | 2.6 | X-RAY DIFFRACTION | 0.252 | 0.196 | false | true | IGHV5 | IGKV8 | Kappa | null | null | null | null | null |
7mej | B | null | 0 | R | protein | null | spike protein s1 | VIRAL PROTEIN/Immune System | 04/06/21 | CryoEM structure of SARS-CoV-2 RBD in complex with nanobodies Nb21 and Nb36 | LAMA GLAMA; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | lama glama | null | severe acute respiratory syndrome coronavirus2 | Huang, W., Taylor, D.J. | 3.55 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
6n4y | E | null | 0 | B | protein | null | metabotropic glutamate receptor 5 | MEMBRANE PROTEIN | 11/20/18 | Metabotropic Glutamate Receptor 5 Extracellular Domain with Nb43 | HOMO SAPIENS; LAMA GLAMA | lama glama | null | homo sapiens | Koehl, A., Hu, H., Feng, D., Sun, B., Chu, M., Weis, W.I., Mathiesen, J.M., Skiniotis, G., Kobilka, B.K. | 3.262 | X-RAY DIFFRACTION | 0.251 | 0.199 | false | true | IGHV1 | null | null | null | null | null | null | null |
7lf0 | Q | O | 0 | J | protein | null | arginase-1 | HYDROLASE/IMMUNE SYSTEM | 01/15/21 | Trimeric human Arginase 1 in complex with mAb2 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Gomez-Llorente, Y., Scapin, G., Palte, R.L. | 3.68 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
5cip | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 07/13/15 | Crystal Structure of Unbound 4E10 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Caaveiro, J.M.M., Rujas, E., Nieva, J.L., Tsumoto, K. | 2.48 | X-RAY DIFFRACTION | 0.231 | 0.183 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
4olv | H | L | 0 | G | protein | null | envelope glycoprotein gp160 | VIRAL PROTEIN/IMMUNE SYSTEM | 01/25/14 | Crystal structure of antibody VRC07-G54F in complex with clade A/E 93TH057 HIV-1 gp120 core | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Kwon, Y.D., Kwong, P.D. | 2.5 | X-RAY DIFFRACTION | 0.253 | 0.203 | false | true | unknown | IGKV3 | Kappa | null | null | null | null | null |
6awq | B | C | 0 | A | protein | null | sodium-dependent serotonin transporter | TRANSPORT PROTEIN | 09/06/17 | Anomalous chloride signal reveals the position of sertraline complexed with the serotonin transporter at the central site | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | Coleman, J.A., Gouaux, E. | 4.046 | X-RAY DIFFRACTION | 0.316 | 0.269 | false | true | IGHV1 | IGKV6 | Kappa | null | null | null | null | null |
4lss | H | L | 0 | G | protein | null | envelope glycoprotein gp120 | viral protein/immune system | 07/23/13 | Crystal structure of broadly and potently neutralizing antibody VRC01 in complex with HIV-1 clade A strain KER_2018_11 gp120 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Zhou, T., Moquin, S., Kwong, P.D. | 2.59 | X-RAY DIFFRACTION | 0.263 | 0.192 | false | true | unknown | IGKV3 | Kappa | null | null | null | null | null |
7kf0 | H | L | 0 | V | protein | null | isoform l-vegf206 of vascular endothelial growth factor a | IMMUNE SYSTEM | 10/13/20 | Crystal structure of bH1 Fab variant (CDR H3 loop design 13_0346) in complex with VEGF | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Shi, R., Picard, M.-E. | 2.32 | X-RAY DIFFRACTION | 0.246 | 0.192 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6t9d | H | L | 0 | C | protein | null | unknown | IMMUNE SYSTEM | 10/28/19 | Crystal structure of a bispecific DutaFab in complex with human VEGF121 | HOMO SAPIENS | null | null | null | Kimbung, R., Logan, D.T., Beckmann, R., Jensen, K., Speck, J., Fenn, S., Kettenberger, H. | 2.905 | X-RAY DIFFRACTION | 0.280 | 0.212 | false | false | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
5zv3 | H | L | 0 | A | peptide | null | peptide from microtubule-associated protein tau | IMMUNE SYSTEM | 05/09/18 | Crystal structure of human anti-tau antibody CBTAU-28.1 in complex with its tau peptide | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | homo sapiens | Zhang, H., Wilson, I.A. | 2.093 | X-RAY DIFFRACTION | 0.251 | 0.187 | false | true | IGHV5 | IGKV4 | Kappa | null | null | null | null | null |
6kn9 | E | e | 0 | B | protein | null | interleukin-18 receptor accessory protein | CYTOKINE | 08/05/19 | Crystal structure of human interleukin 18 receptor beta extracellular domain in complex with an antagonistic scFv | HOMO SAPIENS | homo sapiens | null | homo sapiens | Wu, D.H., Liu, C.C. | 3.302 | X-RAY DIFFRACTION | 0.277 | 0.247 | true | true | unknown | unknown | unknown | null | null | null | null | null |
6qna | A | B | 0 | null | null | null | null | IMMUNE SYSTEM | 02/10/19 | Structure of bovine anti-RSV hybrid Fab B13HC-B4LC | BOS TAURUS | bos taurus | bos taurus | null | Ren, J., Nettleship, J.E., Harris, G., Mwangi, W., Rhaman, N., Grant, C., Kotecha, A., Fry, E., Charleston, B., Stuart, D.I., Hammond, J., Owens, R.J. | 2.62 | X-RAY DIFFRACTION | 0.250 | 0.220 | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
7k7y | D | null | 0 | A | protein | null | botulinum neurotoxin type e | ANTITOXIN | 09/24/20 | Crystal structure of BoNT/E LC-HN domain in complex with VHH JLE-E9 | CLOSTRIDIUM BOTULINUM; VICUGNA PACOS | vicugna pacos | null | clostridium botulinum | Lam, K., Jin, R. | 3.6 | X-RAY DIFFRACTION | 0.288 | 0.261 | false | true | IGHV1 | null | null | null | null | null | null | null |
3u6r | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 10/12/11 | Three dimensional structure of broadly neutralizing anti - Hepatitis C virus (HCV) glycoprotein E2 single chain FV fragment 1:7 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Gilmartin, A.A., Lamp, B., Ruemenapf, T., Persson, A.A., Rey, F.A., Krey, T. | 2.67 | X-RAY DIFFRACTION | 0.232 | 0.190 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
6qbc | H | L | 0 | null | null | null | null | APOPTOSIS | 12/20/18 | structure of anti-Mcl1 Fab | HOMO SAPIENS | homo sapiens | homo sapiens | null | Luptak, J. | 1.56 | X-RAY DIFFRACTION | 0.233 | 0.204 | false | true | IGHV3 | IGLV1 | Lambda | null | null | null | null | null |
7ora | F | G | 0 | R | protein | null | spike protein s1 | VIRAL PROTEIN | 06/04/21 | Crystal structure of the T478K mutant receptor binding domain of SARS-CoV-2 Spike glycoprotein in complex with COVOX-45 and COVOX-253 Fabs | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Zhou, D., Ren, J., Stuart, D.I. | 2.6 | X-RAY DIFFRACTION | 0.245 | 0.204 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
4jpk | H | L | 0 | A | protein | null | germline-targeting hiv-1 gp120 engineered outer domain,eod-gt6 | IMMUNE SYSTEM/VIRAL PROTEIN | 03/19/13 | Crystal structure of the germline-targeting HIV-1 gp120 engineered outer domain eOD-GT6 in complex with a putative VRC01 germline precursor Fab | ESCHERICHIA COLI; HUMAN IMMUNODEFICIENCY VIRUS 1 | null | null | human immunodeficiency virus 1 | Julien, J.-P., Jardine, J., Schief, W.R., Wilson, I.A. | 2.4 | X-RAY DIFFRACTION | 0.263 | 0.200 | false | true | IGHV1 | IGKV3 | Kappa | 0 | -10.036126 | SPR | null | TBD |
4rqq | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 11/04/14 | Crystal structure of human Fab PGDM1400, a broadly reactive and potent HIV-1 neutralizing antibody | HOMO SAPIENS | homo sapiens | homo sapiens | null | Julien, J.-P., Wilson, I.A. | 3.1 | X-RAY DIFFRACTION | 0.253 | 0.221 | false | true | unknown | IGKV2 | Kappa | null | null | null | null | null |
6w0h | A | B | 0 | C | protein | null | ph-gated potassium channel kcsa | MEMBRANE PROTEIN | 02/29/20 | Closed-gate KcsA soaked in 5mM KCl/5mM BaCl2 | RATTUS NORVEGICUS; STREPTOMYCES LIVIDANS | rattus norvegicus | rattus norvegicus | streptomyces lividans | Rohaim, A., Gong, L., Li, J. | 2.6 | X-RAY DIFFRACTION | 0.239 | 0.194 | false | true | IGHV1 | IGKV5 | Kappa | null | null | null | null | null |
4k07 | null | B | 0 | null | null | null | null | IMMUNE SYSTEM | 04/03/13 | Crystal structure of the amyloid-forming immunoglobulin AL-103 cis-proline 95 mutant | HOMO SAPIENS | null | homo sapiens | null | Thompson, J.R., Berkholz, D.S., Mahlum, E.W., Ramirez-Alvarado, M. | 2.83 | X-RAY DIFFRACTION | 0.236 | 0.202 | false | true | null | IGKV1 | Kappa | null | null | null | null | null |
1vfa | B | A | 0 | null | null | null | null | IMMUNOGLOBULIN | 12/03/93 | BOUND WATER MOLECULES AND CONFORMATIONAL STABILIZATION HELP MEDIATE AN ANTIGEN-ANTIBODY ASSOCIATION | MUS MUSCULUS | mus musculus | mus musculus | null | Bhat, T.N., Poljak, R.J. | 1.8 | X-RAY DIFFRACTION | unknown | 0.158 | false | true | IGHV2 | IGKV12 | Kappa | null | null | null | null | null |
6x78 | B | A | 0 | I | peptide | null | hiv fusion peptide 512-519 v2 | IMMUNE SYSTEM/VIRAL PROTEIN | 05/29/20 | Vaccine-elicited mouse FP-targeting neutralizing antibody vFP48.03 in complex with HIV fusion peptide (residue 512-519) | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | human immunodeficiency virus 1 | Xu, K., Kwong, P.D. | 2.359 | X-RAY DIFFRACTION | 0.226 | 0.178 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
6ymq | C | c | 0 | J | protein | null | triggering receptor expressed on myeloid cells 2 | IMMUNE SYSTEM | 04/09/20 | TREM2 extracellular domain (19-131) in complex with single-chain variable 4 (scFv-4) | HOMO SAPIENS | homo sapiens | null | homo sapiens | Szykowska, A., Preger, C., Scacioc, A., Mukhopadhyay, S.M.M., McKinley, G., Graslund, S., Wigren, E., Persson, H., von Delft, F., Arrowsmith, C.H., Edwards, A., Bountra, C., Di Daniel, E., Davis, J.B., Burgess-Brown, N., Bullock, A. | 3.07 | X-RAY DIFFRACTION | 0.288 | 0.274 | true | true | unknown | unknown | unknown | null | null | null | null | null |
7we7 | J | M | 0 | E | protein | null | spike glycoprotein | IMMUNE SYSTEM/VIRAL PROTEIN | 12/23/21 | SARS-CoV-2 Omicron variant spike protein in complex with Fab XGv282 | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Wang, X., Wang, L. | 3.8 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
5otj | B | A | 0 | D | protein | null | polcalcin phl p 7 | IMMUNE SYSTEM | 08/22/17 | Monomeric polcalcin (Phl p 7) in complex with two identical allergen-specific antibodies | HOMO SAPIENS; PHLEUM PRATENSE | homo sapiens | homo sapiens | phleum pratense | Mitropoulou, A.N., Davies, A.M., Beavil, A.J., McDonnell, J.M., Sutton, B.J. | 2.35 | X-RAY DIFFRACTION | 0.235 | 0.199 | false | true | IGHV1 | IGLV1 | Lambda | 0 | -13.328052 | SPR | null | TBD |
1a6v | J | N | 0 | J | Hapten | NPC | 4-HYDROXY-3-NITROPHENYLACETYL-EPSILON-AMINOCAPROIC ACID ANION | IMMUNOGLOBULIN | 03/03/98 | B1-8 FV FRAGMENT COMPLEXED WITH A (4-HYDROXY-3-NITROPHENYL) ACETATE COMPOUND | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Simon, T., Henrick, K., Hirshberg, M., Winter, G. | 1.8 | X-RAY DIFFRACTION | unknown | 0.296 | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
6mqm | G | H | 0 | I | peptide | null | hiv env fusion peptide residue 512-519 | IMMUNE SYSTEM | 10/10/18 | Vaccine-elicited NHP FP-targeting neutralizing antibody DF1W-a.01 in complex with HIV fusion peptide (residue 512-519) | PLATYRRHINI; SYNTHETIC CONSTRUCT | platyrrhini | platyrrhini | human immunodeficiency virus 1 | Xu, K., Wang, Y., Kwong, P.D. | 3.484 | X-RAY DIFFRACTION | 0.246 | 0.200 | false | true | IGHV4 | IGKV2 | Kappa | null | null | null | null | null |
6mxt | N | null | 0 | A | protein | null | endolysin, beta-2 adrenergic receptor chimera | SIGNALING PROTEIN/HORMONE | 10/31/18 | Crystal structure of human beta2 adrenergic receptor bound to salmeterol and Nb71 | ENTEROBACTERIA PHAGE T4; HOMO SAPIENS; LAMA GLAMA | lama glama | null | enterobacteria phage t4, homo sapiens | Masureel, M., Zou, Y., Picard, L.P., van der Westhuizen, E., Mahoney, J.P., Rodrigues, J.P.G.L.M., Mildorf, T.J., Dror, R.O., Shaw, D.E., Bouvier, M., Pardon, E., Steyaert, J., Sunahara, R.K., Weis, W.I., Zhang, C., Kobilka, B.K. | 2.95934 | X-RAY DIFFRACTION | 0.245 | 0.205 | false | true | IGHV1 | null | null | null | null | null | null | null |
7f7h | A | B | 0 | E | protein | null | spike glycoprotein s1 | VIRAL PROTEIN/IMMUNE SYSTEM | 06/29/21 | SARS-CoV-2 S protein RBD in complex with A8-1 Fab | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Dou, Y., Wang, X., Wang, K., Liu, P., Lu, B. | 3.19 | X-RAY DIFFRACTION | 0.275 | 0.205 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
3ri5 | F | N | 0 | B | protein | null | avermectin-sensitive glutamate-gated chloride channel gluclalpha | transport protein/immune system | 04/12/11 | C. elegans glutamate-gated chloride channel (GluCl) in complex with Fab, ivermectin and picrotoxin | CAENORHABDITIS ELEGANS; MUS MUSCULUS | mus musculus | mus musculus | caenorhabditis elegans | Hibbs, R.E., Gouaux, E. | 3.4 | X-RAY DIFFRACTION | 0.248 | 0.232 | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
4r90 | H | L | 0 | null | null | null | null | Immune System | 09/03/14 | Anti CD70 Llama glama Fab 27B3 | LLAMA GLAMA | lama glama | lama glama | null | Klarenbeek, A., El Mazouari, K., Desmyter, A., Blanchetot, C., Hultberg, A., Roovers, R.C., Cambillau, C., Spinelli, S., Del-Favero, J., Verrips, T., de Haard, H., Achour, I. | 1.746 | X-RAY DIFFRACTION | 0.185 | 0.163 | false | true | IGHV3 | IGLV8 | Lambda | null | null | null | null | null |
7sl9 | B | null | 0 | A | protein | null | sodium-coupled monocarboxylate transporter 1 | MEMBRANE PROTEIN | 10/23/21 | CryoEM structure of SMCT1 | HOMO SAPIENS; SYNTHETIC CONSTRUCT | synthetic construct | null | homo sapiens | Qu, Q., Han, L., Panova, O., Feng, L., Skiniotis, G. | 3.5 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
5tbd | A | B | 0 | C | peptide | null | merozoite surface protein 2 | IMMUNE SYSTEM | 09/12/16 | Crystal Structure of anti-MSP2 Fv fragment (mAb4D11) in complex with 3D7-MSP2 215-222 | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | plasmodium falciparum 3d7 | Seow, J., Morales, R.A.V., MacRaild, C.A., Bankala, K., Drinkwater, N., Dingjan, T., Jaipuria, G., Wilde, K., Anders, R.F., Atreya, H.S., Christ, D., McGowan, S., Norton, R.S. | 2.2 | X-RAY DIFFRACTION | 0.247 | 0.207 | false | true | IGHV14 | IGKV1 | Kappa | null | null | null | null | null |
6uda | C | D | 0 | A | protein | null | ch505.n279k.g458y.sosip.664 gp120 | VIRAL PROTEIN/Immune System | 09/19/19 | Cryo-EM structure of CH235UCA bound to Man5-enriched CH505.N279K.G458Y.SOSIP.664 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Henderson, R., Acharya, P. | 4.2 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
5feh | F | E | 0 | null | null | null | null | IMMUNE SYSTEM | 12/17/15 | Crystal structure of PCT64_35B, a broadly neutralizing anti-HIV antibody | HOMO SAPIENS | homo sapiens | homo sapiens | null | Murrell, S., Wilson, I.A. | 3.1 | X-RAY DIFFRACTION | 0.279 | 0.259 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
2hrp | N | M | 0 | Q | peptide | null | hiv-1 protease peptide | COMPLEX (IMMUNOGLOBULIN/PEPTIDE) | 12/27/96 | ANTIGEN-ANTIBODY COMPLEX | MUS MUSCULUS | mus musculus | mus musculus | null | Lescar, J., Bentley, G.A. | 2.2 | X-RAY DIFFRACTION | 0.289 | 0.198 | false | false | IGHV5 | IGKV3 | Kappa | 0 | -11.32 | SPR | null | 9150407 |
6qf9 | A | a | 0 | null | null | null | null | APOPTOSIS | 01/09/19 | Structure of an anti-Mcl1 scFv | HOMO SAPIENS | homo sapiens | null | null | Luptak, J. | 1.43 | X-RAY DIFFRACTION | 0.216 | 0.185 | true | true | unknown | unknown | unknown | null | null | null | null | null |
7rtp | null | A | 0 | B | Hapten | NY9 | N-{2-[7-(diethylamino)-4-methyl-2-oxo-2H-1-benzopyran-3-yl]ethyl}-N'-[(pyridin-3-yl)methyl]urea | IMMUNE SYSTEM | 08/13/21 | Structure of full-length human lambda-6A light chain JTO in complex with urea stabilizer 20 [1-(2-(7-(diethylamino)-4-methyl-2-oxo-2H-chromen-3-yl)ethyl)-3-(pyridin-3-ylmethyl)urea] | HOMO SAPIENS | null | homo sapiens | homo sapiens | Yan, N.L., Wilson, I.A., Kelly, J.W. | 2.09 | X-RAY DIFFRACTION | 0.238 | 0.179 | false | true | null | IGLV6 | Lambda | null | null | null | null | null |
3ezj | F | null | 0 | E | protein | null | general secretion pathway protein gspd | PROTEIN TRANSPORT | 10/22/08 | Crystal structure of the N-terminal domain of the secretin GspD from ETEC determined with the assistance of a nanobody | ESCHERICHIA COLI; LAMA GLAMA | lama glama | null | escherichia coli | Korotkov, K.V, Pardon, E., Steyaert, J., Hol, W.G. | 2.8 | X-RAY DIFFRACTION | 0.239 | 0.192 | false | true | IGHV1 | null | null | null | null | null | null | null |
6bkc | H | L | 0 | E | protein | null | polyprotein | IMMUNE SYSTEM | 11/08/17 | Structure of Hepatitis C Virus Envelope Glycoprotein E2 core from genotype 6a bound to broadly neutralizing antibody AR3B | HOMO SAPIENS; RECOMBINANT HEPATITIS C VIRUS HK6A/JFH-1 | homo sapiens | homo sapiens | recombinant hepatitis c virus hk6a/jfh-1 | Tzarum, N., Wilson, I.A., Law, M. | 2.6 | X-RAY DIFFRACTION | 0.276 | 0.231 | false | true | IGHV1 | IGKV3 | Kappa | 0 | -12.410406 | BLI | null | TBD |
6yor | H | L | 0 | E | protein | null | rbd | VIRAL PROTEIN | 04/15/20 | Structure of the SARS-CoV-2 spike S1 protein in complex with CR3022 Fab | SEVERE ACUTE RESPIRATORY SYNDROME-RELATED CORONAVIRUS; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome-relatedcoronavirus | Huo, J., Zhao, Y., Ren, J., Zhou, D., Duyvesteyn, H.M.E., Carrique, L., Malinauskas, T., Ruza, R.R., Shah, P.N.M., Fry, E.E., Owens, R., Stuart, D.I. | 3.9 | ELECTRON MICROSCOPY | null | null | false | true | IGHV5 | IGKV4 | Kappa | null | null | null | null | null |
4pb9 | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 04/11/14 | Structure of the Fab fragment of the anti-Francisella tularensis GroEL antibody Ab64 | MUS MUSCULUS | mus musculus | mus musculus | null | Lu, Z., Rynkiewicz, M.J., Seaton, B.A., Sharon, J. | 2.6 | X-RAY DIFFRACTION | 0.240 | 0.185 | false | false | IGHV1 | IGKV2 | Kappa | null | null | null | null | null |
6nb7 | D | E | 0 | B | protein | null | spike glycoprotein | VIRUS | 12/06/18 | SARS-CoV complex with human neutralizing S230 antibody Fab fragment (state 2) | SARS CORONAVIRUS; HOMO SAPIENS | homo sapiens | homo sapiens | sars coronavirus | Walls, A.C., Xiong, X., Park, Y.J., Tortorici, M.A., Snijder, S., Quispe, J., Cameroni, E., Gopal, R., Mian, D., Lanzavecchia, A., Zambon, M., Rey, F.A., Corti, D., Veesler, D., Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 4.5 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV2 | Kappa | null | null | null | null | null |
6nm6 | U | V | 0 | G | protein | null | envelope glycoprotein gp120 | IMMUNE SYSTEM | 01/10/19 | Crystal Structure of HIV-1 BG505 SOSIP.664 Prefusion Env Trimer Bound to N6 FR3-03 scFv in Complex with Crystallization Chaperones 3H109L Fab and 35O22 scFv at 3.2 Angstrom | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Lai, Y.-T., Kwong, P.D. | 2.739 | X-RAY DIFFRACTION | 0.288 | 0.240 | false | true | unknown | unknown | unknown | null | null | null | null | null |
5f3b | A | B | 0 | C | protein | null | growth/differentiation factor 8 | Signaling Protein/Immune System | 12/02/15 | Structure of myostatin in complex with chimeric RK35 antibody | MUS MUSCULUS; HOMO SAPIENS | mus musculus | mus musculus | homo sapiens | Parris, K.D., Mosyak, L. | 1.76 | X-RAY DIFFRACTION | 0.206 | 0.179 | false | true | IGHV5 | IGKV6 | Kappa | 0 | -15.720019 | SPR | null | TBD |
7rmg | N | null | 0 | A | B | protein | protein | NA | NA | guanine nucleotide-binding protein g(s) subunit alphaisoforms short, with certain residues mutated to match guanine nucleotide-binding protein g(q) subunit | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | SIGNALING PROTEIN/MEMBRANE PROTEIN | 07/27/21 | Substance P bound to active human neurokinin 1 receptor in complex with miniGs/q70 | HOMO SAPIENS; LAMA GLAMA; SYNTHETIC CONSTRUCT | lama glama | null | homo sapiens | homo sapiens | Harris, J.A., Faust, B., Gondin, A.B., Daemgen, M.A., Suomivuori, C.M., Veldhuis, N.A., Cheng, Y., Dror, R.O., Thal, D., Manglik, A. | 3 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | null | null | null | null | null | null | null |
7kmk | I | M | 0 | B | protein | null | spike glycoprotein | Viral protein/Immune System | 11/03/20 | cryo-EM structure of SARS-CoV-2 spike in complex with Fab 15033-7, two RBDs bound | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Li, Z., Rini, J.M. | 4.2 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
3chn | D | N | 1 | null | null | null | null | IMMUNE SYSTEM | 03/10/08 | Solution structure of human secretory IgA1 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Bonner, A., Almogren, A., Furtado, P.B., Kerr, M.A., Perkins, S.J. | NOT | SOLUTION SCATTERING / HOMOLOGY MODEL | null | null | false | false | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
5bk5 | F | E | 0 | null | null | null | null | IMMUNE SYSTEM | 09/12/17 | Crystal structure of the anti-circumsporozoite protein 663 germline antibody | HOMO SAPIENS | homo sapiens | homo sapiens | null | Scally, S.W., Bosch, A., Triller, G., Wardemann, H., Julien, J.P. | 3.0 | X-RAY DIFFRACTION | 0.314 | 0.257 | false | true | IGHV3 | IGKV2 | Kappa | null | null | null | null | null |
5fuc | V | null | 0 | D | A | protein | protein | NA | NA | interleukin-6 receptor subunit alpha, interleukin-6receptor | interleukin-6 | IMMUNE SYSTEM | 01/25/16 | Biophysical and cellular characterisation of a junctional epitope antibody that locks IL-6 and gp80 together in a stable complex: implications for new therapeutic strategies | HOMO SAPIENS; CAMELUS DROMEDARIUS | camelus dromedarius | null | homo sapiens | homo sapiens | Adams, R., Griffin, R., Doyle, C., Ettorre, A. | 2.7 | X-RAY DIFFRACTION | 0.287 | 0.231 | false | true | IGHV1 | null | null | null | null | null | null | null |
2dqc | H | L | 0 | Y | protein | null | lysozyme c | IMMUNE SYSTEM/HYDROLASE | 05/25/06 | Crystal structure of hyhel-10 FV mutant(Hy33f) complexed with hen egg lysozyme | MUS MUSCULUS; GALLUS GALLUS | mus musculus | mus musculus | gallus gallus | Shiroishi, M., Kondo, H., Tsumoto, K., Kumagai, I. | 1.8 | X-RAY DIFFRACTION | 0.223 | 0.190 | false | true | IGHV3 | IGKV5 | Kappa | null | null | null | null | null |
1xf3 | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 09/13/04 | Structure of ligand-free Fab DNA-1 in space group P65 | MUS MUSCULUS | mus musculus | mus musculus | null | Schuermann, J.P., Prewitt, S.P., Deutscher, S.L., Tanner, J.J. | 2.3 | X-RAY DIFFRACTION | 0.243 | 0.208 | false | true | IGHV1 | IGKV12 | Kappa | null | null | null | null | null |
7oau | F | null | 0 | E | protein | null | unknown | ANTIVIRAL PROTEIN | 04/20/21 | Nanobody C5 bound to Kent variant RBD (N501Y) | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; LAMA GLAMA | null | null | null | Naismith, J.H., Mikolajek, H. | 1.65 | X-RAY DIFFRACTION | 0.199 | 0.175 | false | false | IGHV1 | null | null | null | null | null | null | null |
1orq | B | A | 0 | C | protein | null | potassium channel | MEMBRANE PROTEIN | 03/14/03 | X-ray structure of a voltage-dependent potassium channel in complex with an Fab | AEROPYRUM PERNIX; MUS MUSCULUS | mus musculus | mus musculus | aeropyrum pernix | Jiang, Y., Lee, A., Chen, J., Ruta, V., Cadene, M., Chait, B.T., MacKinnon, R. | 3.2 | X-RAY DIFFRACTION | 0.298 | 0.253 | false | false | IGHV3 | IGKV4 | Kappa | null | null | null | null | null |
6mu8 | H | L | 0 | G | protein | null | envelope glycoprotein gp160 | IMMUNE SYSTEM/INHIBITOR | 10/22/18 | Crystal Structure of HIV-1 BG505 SOSIP.664 Prefusion Env Trimer Bound to Small Molecule HIV-1 Entry Inhibitor BMS-386150 in Complex with Human Antibodies 3H109L and 35O22 at 3.5 Angstrom | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Lai, Y.-T., Kwong, P.D. | 2.993 | X-RAY DIFFRACTION | 0.259 | 0.219 | false | true | IGHV4 | unknown | unknown | null | null | null | null | null |
7pc2 | Q | R | 0 | A | protein | null | gp120, bg505 sosip.664 t332n | VIRAL PROTEIN | 08/03/21 | HIV-1 Env (BG505 SOSIP.664) in complex with the IgA bNAb 7-269 and the antibody 3BNC117. | HOMO SAPIENS; HUMAN IMMUNODEFICIENCY VIRUS | homo sapiens | homo sapiens | human immunodeficiency virus | Fernandez, I., Bontems, F., Pehau-Arnaudet, G., Rey, F. | 2.8 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
7fjs | H | L | 0 | E | protein | null | spike protein s1 | IMMUNE SYSTEM/VIRAL PROTEIN | 08/04/21 | Crystal structure of T6 Fab bound to theSARS-CoV-2 RBD of B.1.351 | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Wang, X., Zhang, L., Zhang, S., Liang, Q. | 2.9 | X-RAY DIFFRACTION | 0.285 | 0.217 | false | true | IGHV1 | IGKV8 | Kappa | null | null | null | null | null |
2i5y | H | L | 0 | G | protein | null | exterior membrane glycoprotein(gp120) | VIRAL PROTEIN/IMMUNE SYSTEM | 08/26/06 | Crystal structure of CD4M47, a scorpion-toxin mimic of CD4, in complex with HIV-1 YU2 GP120 envelope glycoprotein and anti-HIV-1 antibody 17B | HUMAN IMMUNODEFICIENCY VIRUS; HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | human immunodeficiency virus | Huang, C.-C., Kwong, P.D. | 2.2 | X-RAY DIFFRACTION | 0.273 | 0.214 | false | true | IGHV1 | IGKV3 | Kappa | 0 | -11.689711 | SPR | null | TBD |
1xgp | B | A | 0 | C | protein | null | lysozyme c | IMMUNE SYSTEM | 09/17/04 | Structure for antibody HyHEL-63 Y33A mutant complexed with hen egg lysozyme | MUS MUSCULUS; GALLUS GALLUS | mus musculus | mus musculus | gallus gallus | Li, Y., Mariuzza, R.A. | 2.1 | X-RAY DIFFRACTION | 0.271 | 0.215 | false | true | IGHV3 | IGKV5 | Kappa | null | null | null | null | null |
7zfa | X | Y | 0 | C | protein | null | spike protein s1 | VIRAL PROTEIN | 04/01/22 | SARS-CoV-2 Omicron RBD in complex with Omi-6 and COVOX-150 Fabs | Homo sapiens; Severe acute respiratory syndrome coronavirus 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Zhou, D., Huo, J., Ren, J., Stuart, D.I. | 4.24 | X-RAY DIFFRACTION | 0.272 | 0.237 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
7u8c | H | L | 0 | 2 | peptide | null | unknown | IMMUNE SYSTEM | 03/08/22 | Crystal structure of Mesothelin C-terminal peptide-MORAb 15B6 FAB complex | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | null | Zhan, J., Esser, L., Xia, D. | 1.74 | X-RAY DIFFRACTION | 0.238 | 0.204 | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
7byr | H | L | 0 | B | protein | null | sars-cov-2 spike glycoprotein | VIRAL PROTEIN | 06/10/20 | BD23-Fab in complex with the S ectodomain trimer | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Zhu, Q., Wang, G., Xiao, J. | 3.84 | ELECTRON MICROSCOPY | null | null | false | true | IGHV7 | IGKV1 | Kappa | null | null | null | null | null |
2w0l | null | D | 0 | null | null | null | null | IMMUNE SYSTEM | 08/19/08 | CRYSTAL STRUCTURE OF THE MUTANT H8P FROM THE RECOMBINANT VARIABLE DOMAIN 6JAL2 | HOMO SAPIENS | null | homo sapiens | null | RUDINO-PINERA, E., GONZALEZRUBIO-GARRIDO, P., HORJALES, E. | 2.2 | X-RAY DIFFRACTION | 0.245 | 0.206 | false | false | null | IGLV6 | Lambda | null | null | null | null | null |
6ba5 | B | A | 0 | M | protein | null | inactive tyrosine-protein kinase transmembrane receptorror1 | IMMUNE SYSTEM | 10/12/17 | Potent and Selective Antitumor Activity of a T-Cell Engaging Bispecific Antibody Targeting a Membrane-Proximal Epitope of ROR1 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Park, H., Rader, C. | 1.62 | X-RAY DIFFRACTION | 0.214 | 0.194 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
3tt3 | H | L | 0 | A | protein | null | leucine transporter leut | TRANSPORT PROTEIN | 09/13/11 | Crystal Structure of LeuT in the inward-open conformation in complex with Fab | AQUIFEX AEOLICUS; MUS MUSCULUS | mus musculus | mus musculus | aquifex aeolicus | Krishnamurthy, H., Gouaux, E. | 3.22 | X-RAY DIFFRACTION | 0.300 | 0.257 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
7lka | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 02/02/21 | Crystal structure of SARS-CoV-2 RBD-targeting antibody COV107-23 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Yuan, M., Zhu, X., Wilson, I.A., Wu, N.C. | 1.981 | X-RAY DIFFRACTION | 0.264 | 0.215 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
3stb | A | null | 0 | D | protein | null | mp18 rna editing complex protein | RNA BINDING PROTEIN/IMMUNE SYSTEM | 07/09/11 | A complex of two editosome proteins and two nanobodies | LAMA GLAMA; TRYPANOSOMA BRUCEI | lama | null | trypanosoma brucei | Park, Y.-J., Hol, W. | 2.5 | X-RAY DIFFRACTION | 0.234 | 0.199 | false | true | IGHV1 | null | null | null | null | null | null | null |
6fab | H | L | 0 | null | null | null | null | IMMUNOGLOBULIN | 01/17/91 | THREE-DIMENSIONAL STRUCTURE OF MURINE ANTI-P-AZOPHENYLARSONATE FAB 36-71. 1. X-RAY CRYSTALLOGRAPHY, SITE-DIRECTED MUTAGENESIS, AND MODELING OF THE COMPLEX WITH HAPTEN | MUS MUSCULUS | mus musculus | mus musculus | null | Strong, R.K., Rose, D.R., Petsko, G.A., Sharon, J., Margolies, M.N. | 1.9 | X-RAY DIFFRACTION | unknown | unknown | false | true | IGHV1 | IGKV10 | Kappa | null | null | null | null | null |
3dwt | E | null | 0 | null | null | null | null | IMMUNE SYSTEM | 07/23/08 | Structure of CabBCII-10 nanobody | CAMELUS DROMEDARIUS | camelus dromedarius | null | null | Vincke, C., Loris, R., Muyldermans, S., Conrath, K. | 2.9 | X-RAY DIFFRACTION | 0.305 | 0.245 | false | true | IGHV1 | null | null | null | null | null | null | null |
2qql | H | L | 0 | A | protein | null | neuropilin-2 | SIGNALING PROTEIN | 07/26/07 | Neuropilin-2 a1a2b1b2 Domains in Complex with a Semaphorin-Blocking Fab | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Appleton, B.A., Wiesmann, C. | 3.1 | X-RAY DIFFRACTION | 0.232 | 0.188 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
2j88 | H | L | 0 | A | protein | null | hyalurononglucosaminidase | HYDROLASE | 10/23/06 | Hyaluronidase in complex with a monoclonal IgG Fab fragment | APIS MELLIFERA; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | apis mellifera | Padavattan, S., Schirmer, T., Housley, Z.Markovic- | 2.6 | X-RAY DIFFRACTION | 0.247 | 0.210 | false | false | IGHV8 | IGKV12 | Kappa | null | null | null | null | null |
7w53 | E | e | 0 | A | B | protein | protein | NA | NA | guanine nucleotide-binding protein g(q) subunit alpha | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | SIGNALING PROTEIN | 11/29/21 | Cryo-EM structure of the neuromedin U-bound neuromedin U receptor 1-Gq protein complex | HOMO SAPIENS | homo sapiens | null | homo sapiens | homo sapiens | You, C., Xu, H.E., Jiang, Y. | 3.2 | ELECTRON MICROSCOPY | null | null | true | true | unknown | unknown | unknown | null | null | null | null | null |
1a4k | B | A | 0 | B | Hapten | FRA | [4-(4-ACETYLAMINO-PHENYL)-3,5-DIOXO-4-AZA-TRICYCLO[5.2.2.0 2,6]UNDEC-1-YLCARBAMOYLOXY]-ACETIC ACID | IMMUNOGLOBULIN | 01/30/98 | DIELS ALDER CATALYTIC ANTIBODY WITH TRANSITION STATE ANALOGUE | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Spiller, B.W., Romesburg, F.E., Schultz, P.G., Stevens, R.C. | 2.4 | X-RAY DIFFRACTION | 0.291 | 0.211 | false | true | IGHV9 | IGKV1 | Kappa | 0 | -10.91 | Other | 25 | 9506942 |
7r8o | O | P | 0 | A | protein | null | spike glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 06/26/21 | Structure of the SARS-CoV-2 S 6P trimer in complex with neutralizing antibody C548 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | DeLaitsch, A.T., Barnes, C.O., Bjorkman, P.J. | 3.5 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGLV9 | Lambda | null | null | null | null | null |
7lj5 | G | F | 0 | B | protein | null | isoform 2 of potassium channel subfamily k member 4 | METAL TRANSPORT/Immune System | 01/28/21 | Human TRAAK K+ channel FHIEG mutant A198E in a K+ bound conductive conformation | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | Rietmeijer, R.A., Brohawn, S.G. | 2.26 | X-RAY DIFFRACTION | 0.252 | 0.220 | false | true | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
5wko | C | D | 0 | X | U | protein | protein | NA | NA | hemagglutinin | hemagglutinin | ANTIVIRAL PROTEIN | 07/25/17 | Crystal structure of antibody 27F3 recognizing the HA from A/California/04/2009 (H1N1) influenza virus | HOMO SAPIENS; INFLUENZA A VIRUS | homo sapiens | homo sapiens | influenza a virus | influenza a virus | Wilson, A., Lang, S., Zhu, X. | 3.492 | X-RAY DIFFRACTION | 0.268 | 0.246 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
4uim | A | B | 0 | null | null | null | null | null | 03/30/15 | crystal structure of quinine-dependent Fab 314.3 | MUS MUSCULUS | mus musculus | mus musculus | null | Zhu, J., Zhu, J., Bougie, D.W., Aster, R.H., Springer, T.A. | 2.7 | X-RAY DIFFRACTION | 0.2596 | 0.2215 | false | false | IGHV1 | IGKV10 | Kappa | null | null | null | null | null |
3r06 | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 03/07/11 | Crystal structure of anti-mouse CD3epsilon antibody 2C11 Fab fragment | CRICETULUS MIGRATORIUS | cricetulus migratorius | cricetulus migratorius | null | Shore, D.A., Zhu, X., Wilson, I.A. | 2.5 | X-RAY DIFFRACTION | 0.236 | 0.191 | false | true | IGHV5 | IGKV14 | Kappa | null | null | null | null | null |
2nr6 | D | C | 0 | A | protein | null | aspartic protease bla g 2 | HYDROLASE/IMMUNE SYSTEM | 11/01/06 | Crystal structure of the complex of antibody and the allergen Bla g 2 | BLATTELLA GERMANICA; MUS MUSCULUS | mus musculus | mus musculus | blattella germanica | Li, M., Gustchina, A., Wlodawer, A., Pomes, A., Wunschmann, S. | 2.81 | X-RAY DIFFRACTION | 0.281 | 0.232 | false | true | IGHV14 | IGKV6 | Kappa | null | null | null | null | null |
5vkk | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 04/21/17 | Crystal structure of Fab fragment of anti-CD22 Epratuzumab | HOMO SAPIENS, MUS MUSCULUS; HOMO SAPIENS | homo sapiens, mus musculus, homo sapiens | homo sapiens, mus musculus, homo sapiens | null | Sicard, T., Ereno Orbea, J., Julien, J.-P. | 2.014 | X-RAY DIFFRACTION | 0.237 | 0.212 | false | true | IGHV1 | IGKV8 | Kappa | null | null | null | null | null |
5hi4 | H | L | 0 | A | protein | null | interleukin-17a | IMMUNE SYSTEM/INHIBITOR | 01/11/16 | Binding site elucidation and structure guided design of macrocyclic IL-17A antagonists | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | homo sapiens | Liu, S. | 1.8 | X-RAY DIFFRACTION | 0.224 | 0.200 | false | true | IGHV3 | IGLV6 | Lambda | null | null | null | null | null |
7m42 | B | A | 0 | E | protein | null | spike protein s1 | VIRAL PROTEIN/IMMUNE SYSTEM | 03/19/21 | Complex of SARS-CoV-2 receptor binding domain with the Fab fragments of neutralizing antibodies REGN10985 and REGN10989 | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Zhou, Y., Romero Hernandez, A., Saotome, K., Franklin, M.C. | 3.3 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGLV2 | Lambda | null | null | null | null | null |
6mek | I | G | 0 | A | protein | null | e2 glycoprotein | IMMUNE SYSTEM | 09/06/18 | Broadly neutralizing antibodies against HCV use a CDRH3 disulfide motif to recognize an E2 glycoprotein site that can be targeted for vaccine design | HEPACIVIRUS C; HOMO SAPIENS | homo sapiens | homo sapiens | hepacivirus c | Flyak, A.I., Bjorkman, P.J. | 3.1 | X-RAY DIFFRACTION | 0.290 | 0.223 | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
6f2g | B | null | 0 | A | protein | null | putative amino acid/polyamine transport protein | TRANSPORT PROTEIN | 11/24/17 | Bacterial asc transporter crystal structure in open to in conformation | CARNOBACTERIUM SP. AT7; LAMA GLAMA | lama glama | null | carnobacterium sp. at7 | Fort, J., Errasti-Murugarren, E., Carpena, X., Palacin, M., Fita, I. | 2.92 | X-RAY DIFFRACTION | 0.261 | 0.238 | false | true | IGHV1 | null | null | null | null | null | null | null |
7jhg | H | L | 0 | A | protein | null | 5'-amp-activated protein kinase catalytic subunit alpha-1 | TRANSFERASE/IMMUNE SYSTEM | 07/20/20 | Cryo-EM structure of ATP-bound fully inactive AMPK in complex with Dorsomorphin (Compound C) and Fab-nanobody | HOMO SAPIENS; ESCHERICHIA COLI K-12; SYNTHETIC CONSTRUCT | synthetic construct | synthetic construct | homo sapiens | Yan, Y., Murkherjee, S., Zhou, X.E., Xu, T.H., Xu, H.E., Kossiakoff, A.A., Melcher, K. | 3.47 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
5imk | B | null | 0 | A | protein | null | v-set and immunoglobulin domain-containing protein 4 | IMMUNE SYSTEM | 03/06/16 | Nanobody targeting human Vsig4 in Spacegroup C2 | HOMO SAPIENS; CAMELIDAE | camelidae | null | homo sapiens | Wen, Y. | 1.227 | X-RAY DIFFRACTION | 0.185 | 0.172 | false | true | IGHV1 | null | null | 0.000001 | -8.281754 | ITC | null | TBD |
6tyl | J | null | 0 | F | protein | null | resistance to inhibitors of cholinesterase 8 homolog a (c.elegans) | SIGNALING PROTEIN | 08/09/19 | Crystal structure of mammalian Ric-8A:Galpha(i):nanobody complex | RATTUS NORVEGICUS; LAMA GLAMA | lama glama | null | rattus norvegicus | Mou, T.C., McClelland, L., Yates-Hansen, C., Sprang, S.R. | 3.3 | X-RAY DIFFRACTION | 0.287 | 0.248 | false | true | IGHV1 | null | null | null | null | null | null | null |
7oay | J | null | 0 | I | protein | null | unknown | ANTIVIRAL PROTEIN | 04/20/21 | Nanobody F2 bound to RBD | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; LAMA GLAMA | null | null | null | Naismith, J.H., Mikolajek, H. | 2.34 | X-RAY DIFFRACTION | 0.228 | 0.192 | false | false | IGHV1 | null | null | null | null | null | null | null |
6obg | D | null | 0 | B | protein | null | ricin a chain | TOXIN | 04/01/20 | Ricin A chain bound to VHH antibody V8E6 | RICINUS COMMUNIS; VICUGNA PACOS | vicugna pacos | null | ricinus communis | Rudolph, M.J. | 1.996 | X-RAY DIFFRACTION | 0.218 | 0.189 | false | true | IGHV1 | null | null | null | null | null | null | null |
1uac | H | L | 0 | Y | protein | null | lysozyme c | IMMUNE SYSTEM/HYDROLASE | 03/08/03 | Crystal Structure of HYHEL-10 FV MUTANT SFSF Complexed with TURKEY WHITE LYSOZYME | MUS MUSCULUS; MELEAGRIS GALLOPAVO | mus musculus | mus musculus | meleagris gallopavo | Kumagai, I., Nishimiya, Y., Kondo, H., Tsumoto, K. | 1.7 | X-RAY DIFFRACTION | unknown | unknown | false | true | IGHV3 | IGKV5 | Kappa | null | null | null | null | null |
7kra | I | J | 0 | A | protein | null | er membrane protein complex subunit 1 | MEMBRANE PROTEIN/IMMUNE SYSTEM | 11/19/20 | Cryo-EM structure of Saccharomyces cerevisiae ER membrane protein complex bound to Fab-DH4 in lipid nanodiscs | HOMO SAPIENS; SACCHAROMYCES CEREVISIAE | homo sapiens | homo sapiens | saccharomyces cerevisiae | Miller-Vedam, L.E., Schirle Oakdale, N.S., Braeuning, B., Boydston, E.A., Sevillano, N., Popova, K.D., Bonnar, J.L., Shurtleff, M.J., Prabu, J.R., Stroud, R.M., Craik, C.S., Schulman, B.A., Weissman, J.S., Frost, A. | 3.2 | ELECTRON MICROSCOPY | null | null | false | true | IGHV4 | IGKV2 | Kappa | null | null | null | null | null |
6eqc | E | e | 0 | B | protein | null | hexon protein | VIRAL PROTEIN | 10/12/17 | Cryo-EM reconstruction of a complex of a binding protein and human adenovirus C5 hexon | MUS MUSCULUS; HUMAN ADENOVIRUS 5 | mus musculus | null | human adenovirus 5 | Schmid, M., Ernst, P., Honegger, A., Suomalainen, M., Zimmermann, M., Braun, L., Stauffer, S., Thom, C., Dreier, B., Eibauer, M., Kipar, A., Vogel, V., Greber, U.F., Medalia, O., Plueckthun, A. | 7.4 | ELECTRON MICROSCOPY | null | null | true | true | unknown | unknown | unknown | null | null | null | null | null |
5w1k | O | N | 0 | P | protein | null | pre-glycoprotein polyprotein gp complex | VIRAL PROTEIN/IMMUNE SYSTEM | 06/03/17 | JUNV GP1 CR1-10 Fab CR1-28 Fab complex | HOMO SAPIENS; JUNIN MAMMARENAVIRUS | homo sapiens | homo sapiens | junin mammarenavirus | Raymond, D.D., Clark, L.E., Abraham, J. | 3.99 | X-RAY DIFFRACTION | 0.288 | 0.237 | false | true | IGHV4 | IGKV3 | Kappa | null | null | null | null | null |
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