pdb stringlengths 4 4 | Hchain stringclasses 59
values | Lchain stringclasses 60
values | model int64 0 76 | antigen_chain stringclasses 386
values | antigen_type stringclasses 24
values | antigen_het_name stringclasses 240
values | antigen_name stringlengths 1 396 ⌀ | short_header stringclasses 448
values | date stringlengths 8 8 | compound stringlengths 4 243 | organism stringlengths 3 175 ⌀ | heavy_species stringclasses 121
values | light_species stringclasses 67
values | antigen_species stringclasses 937
values | authors stringlengths 6 762 | resolution stringlengths 1 8 | method stringclasses 10
values | r_free stringclasses 354
values | r_factor stringclasses 342
values | scfv bool 2
classes | engineered bool 2
classes | heavy_subclass stringclasses 14
values | light_subclass stringclasses 35
values | light_ctype stringclasses 3
values | affinity float64 0 0 ⌀ | delta_g float64 -16.91 -5.04 ⌀ | affinity_method stringclasses 11
values | temperature float64 4 37 ⌀ | pmid stringclasses 157
values |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1mel | A | null | 0 | L | protein | null | lysozyme | COMPLEX (ANTIBODY/ANTIGEN) | 06/06/96 | CRYSTAL STRUCTURE OF A CAMEL SINGLE-DOMAIN VH ANTIBODY FRAGMENT IN COMPLEX WITH LYSOZYME | CAMELUS DROMEDARIUS; GALLUS GALLUS | camelus dromedarius | null | gallus gallus | Desmyter, A., Transue, T.R., Arbabi Gharoudi, M., Dao Thi, M., Poortmans, F., Hamers, R., Muyldermans, S., Wyns, L. | 2.5 | X-RAY DIFFRACTION | 0.323 | 0.221 | false | true | IGHV1 | null | null | null | null | null | null | null |
4p2c | H | null | 0 | C | protein | null | shiga toxin 2e, subunit b | TOXIN | 03/03/14 | Complex of Shiga toxin 2e with a neutralizing single-domain antibody | ESCHERICHIA COLI; LAMA GLAMA | lama glama | null | escherichia coli | Lo, A.W.H., Moonens, K., De Kerpel, M., Brys, L., Pardon, E., Remaut, H., De Greve, H. | 2.818 | X-RAY DIFFRACTION | 0.253 | 0.187 | false | true | IGHV1 | null | null | null | null | null | null | null |
5tqa | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 10/23/16 | Crystal Structure of DH270.6 (unliganded) from the DH270 Broadly Neutralizing N332-Glycan Dependent Lineage | HOMO SAPIENS | homo sapiens | homo sapiens | null | Fera, D., Harrison, S.C. | 2.723 | X-RAY DIFFRACTION | 0.201 | 0.185 | false | true | IGHV1 | IGLV2 | Lambda | null | null | null | null | null |
2bse | F | null | 0 | C | protein | null | receptor binding protein | RECEPTOR | 05/20/05 | Structure of Lactococcal Bacteriophage p2 Receptor Binding Protein in complex with a llama VHH domain | LACTOCOCCUS LACTIS PHAGE P2; LAMA GLAMA | lama glama | null | lactococcus lactis phage p2 | Spinelli1, S., Desmyter, A., Verrips, C.T., deHaard, H.J.W., Moineau, S., Cambillau, C. | 2.7 | X-RAY DIFFRACTION | 0.294 | 0.251 | false | true | IGHV1 | null | null | null | null | null | null | null |
7m8l | N | Q | 0 | E | protein | null | virion spike glycoprotein 2 | VIRAL PROTEIN/IMMUNE SYSTEM | 03/30/21 | EBOV GP bound to rEBOV-442 and rEBOV-515 Fabs | EBOLA VIRUS; HOMO SAPIENS | homo sapiens | homo sapiens | ebola virus | Murin, C.D., Ward, A.B. | 3.9 | ELECTRON MICROSCOPY | null | null | false | true | IGHV4 | IGKV3 | Kappa | null | null | null | null | null |
7lk4 | F | E | 0 | P | protein | null | bcl-2 homologous antagonist/killer | APOPTOSIS | 02/01/21 | Crystal structure of BAK L100A in complex with activating antibody fragments | HOMO SAPIENS; RATTUS NORVEGICUS | rattus norvegicus | rattus norvegicus | homo sapiens | Robin, Y.A., Colman, P.M. | 3.1 | X-RAY DIFFRACTION | 0.262 | 0.214 | false | true | IGHV5 | IGKV16 | Kappa | null | null | null | null | null |
7r24 | E | null | 0 | A | protein | null | activity-regulated cytoskeleton-associated protein | STRUCTURAL PROTEIN | 02/04/22 | Crystal structure of rat Arc CTD in complex with two anti-Arc nanobodies | RATTUS NORVEGICUS; VICUGNA PACOS | vicugna pacos | null | rattus norvegicus | Markusson, S., Kursula, P. | 2.7 | X-RAY DIFFRACTION | 0.274 | 0.257 | false | true | IGHV1 | null | null | null | null | null | null | null |
1rhh | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 11/14/03 | Crystal Structure of the Broadly HIV-1 Neutralizing Fab X5 at 1.90 Angstrom Resolution | HOMO SAPIENS | homo sapiens | homo sapiens | null | Darbha, R., Phogat, S., Labrijn, A.F., Shu, Y., Gu, Y., Andrykovitch, M., Zhang, M.Y., Pantophlet, R., Martin, L., Vita, C., Burton, D.R., Dimitrov, D.S., Ji, X. | 1.9 | X-RAY DIFFRACTION | 0.227 | 0.224 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
3j8w | F | J | 0 | D | protein | null | l1 | VIRUS/IMMUNE SYSTEM | 11/19/14 | Cryo-EM reconstruction of quasi-HPV16 complex with H263.A2 Fab | MUS MUSCULUS; HUMAN PAPILLOMAVIRUS TYPE 16 | mus musculus | mus musculus | human papillomavirus type 16 | Guan, J., Hafenstein, S. | 13 | ELECTRON MICROSCOPY | null | null | false | false | IGHV1 | IGKV12 | Kappa | null | null | null | null | null |
5u7o | H | L | 0 | G | protein | null | envelope glycoprotein gp160 | VIRAL PROTEIN/Immune System | 12/12/16 | Crystal Structure of HIV-1 BG505 SOSIP.664 Prefusion Env Trimer bound to small molecule HIV-1 entry inhibitor BMS-626529 in Complex with Human Antibodies PGT122 and 35O22 at 3.8 A | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Pancera, M., Lai, Y.-T., Kwong, P.D. | 3.031 | X-RAY DIFFRACTION | 0.325 | 0.272 | false | true | IGHV4 | IGLV3 | Lambda | 0 | -9.73617 | Unknown | null | TBD |
7mhx | A | B | 0 | C | protein | null | ph-gated potassium channel kcsa | MEMBRANE PROTEIN | 04/15/21 | KcsA E71V closed gate with Ba2+ | MUS MUSCULUS; STREPTOMYCES LIVIDANS | mus musculus | mus musculus | streptomyces lividans | Rohaim, A., Li, J., Weingarth, M., Roux, B. | 2.85 | X-RAY DIFFRACTION | 0.244 | 0.202 | false | true | IGHV1 | IGKV5 | Kappa | null | null | null | null | null |
5uk4 | r | null | 0 | R | protein | null | anti-vesicular stomatitis virus n vhh | Viral Protein/RNA/Immune System | 01/19/17 | VESICULAR STOMATITS VIRUS N PROTEIN IN COMPLEX WITH INHIBITORY NANOBODY 1307 | VESICULAR STOMATITIS INDIANA VIRUS (STRAIN SAN JUAN); VICUGNA PACOS | vicugna pacos | null | vesicular stomatitis indiana virus (strain sanjuan) | Hanke, L., Knockenhauer, K.E., Ploegh, H.L., Schwartz, T.U. | 3.204 | X-RAY DIFFRACTION | 0.288 | 0.237 | false | false | IGHV1 | null | null | null | null | null | null | null |
3v6f | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 12/19/11 | Crystal Structure of an anti-HBV e-antigen monoclonal Fab fragment (e6), unbound | MUS MUSCULUS | mus musculus | mus musculus | null | Dimattia, M.A., Watts, N.R., Stahl, S.J., Grimes, J.M., Steven, A.C., Stuart, D.I., Wingfield, P.T. | 2.52 | X-RAY DIFFRACTION | 0.220 | 0.179 | false | false | IGHV5 | IGKV8 | Kappa | null | null | null | null | null |
6ev1 | C | D | 0 | null | null | null | null | IMMUNE SYSTEM | 11/01/17 | Crystal structure of antibody against schizophyllan | MUS MUSCULUS | mus musculus | mus musculus | null | Sung, K.H., Josewski, J., Dubel, S., Blankenfeldt, W., Rau, U. | 3.043 | X-RAY DIFFRACTION | 0.238 | 0.186 | false | true | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
2gjj | a | A | 0 | null | null | null | null | IMMUNE SYSTEM | 03/31/06 | Crystal structure of a single chain antibody scA21 against Her2/ErbB2 | MUS MUSCULUS | null | mus musculus | null | Zhu, Z. | 2.1 | X-RAY DIFFRACTION | 0.226 | 0.189 | true | true | unknown | unknown | unknown | null | null | null | null | null |
6dzm | J | L | 0 | F | C | protein | protein | NA | NA | bundibugyo virus gp2 | bundibugyo virus gp1 | VIRAL PROTEIN | 07/05/18 | Bundibugyo virus GP (mucin-deleted) in complex with pan-ebolavirus human antibody ADI-15878 Fab | BUNDIBUGYO EBOLAVIRUS; HOMO SAPIENS | homo sapiens | homo sapiens | bundibugyo ebolavirus | bundibugyo ebolavirus | Murin, C.D., Ward, A.B. | 4.29 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
5mp6 | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 12/15/16 | Structure of the Unliganded Fab from HIV-1 Neutralizing Antibody CAP248-2B that Binds to the gp120 C-terminus - gp41 Interface, at two Angstrom resolution. | HOMO SAPIENS | homo sapiens | homo sapiens | null | Wibmer, C.K., Gorman, J., Kwong, P.D. | 1.959 | X-RAY DIFFRACTION | 0.240 | 0.198 | false | true | IGHV4 | IGLV2 | Lambda | null | null | null | null | null |
3uc0 | I | M | 0 | B | protein | null | envelope protein | VIRAL PROTEIN/IMMUNE SYSTEM | 10/25/11 | Crystal structure of domain I of the envelope glycoprotein ectodomain from dengue virus serotype 4 in complex with the fab fragment of the chimpanzee monoclonal antibody 5H2 | DENGUE VIRUS 4; PAN TROGLODYTES | pan troglodytes | pan troglodytes | dengue virus 4 | Cockburn, J.J.B., Stura, E.A., Navarro-Sanchez, M.E., Rey, F.A. | 2.71 | X-RAY DIFFRACTION | 0.252 | 0.220 | false | true | IGHV4 | IGKV1 | Kappa | 0 | -12.6 | Other | 37 | 22139356 |
6um7 | J | K | 0 | A | protein | null | envelope glycoprotein gp120 | VIRAL PROTEIN/immune system | 10/09/19 | Cryo-EM structure of vaccine-elicited HIV-1 neutralizing antibody DH270.mu1 in complex with CH848 10.17DT Env | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Acharya, P., Henderson, R.C., Saunders, K., Haynes, B.F. | 3.5 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGLV2 | Lambda | null | null | null | null | null |
1u8p | B | A | 0 | C | peptide | null | gp41 peptide | IMMUNE SYSTEM | 08/06/04 | Crystal structure of the HIV-1 Cross Neutralizing Monoclonal Antibody 2F5 in complex with gp41 Peptide ECDKWCS | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Bryson, S., Julien, J.-P., Hynes, R.C., Pai, E.F. | 3.23 | X-RAY DIFFRACTION | 0.222 | 0.212 | false | false | IGHV2 | IGKV1 | Kappa | null | null | null | null | null |
3oau | H | L | 0 | H | carbohydrate | MAN | polysaccharide | IMMUNE SYSTEM | 08/05/10 | Antibody 2G12 Recognizes Di-Mannose Equivalently in Domain- and Non-Domain-Exchanged Forms, but only binds the HIV-1 Glycan Shield if Domain-Exchanged | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Doores, K.J., Fulton, Z., Huber, M., Wilson, I.A., Burton, D.R. | 1.9 | X-RAY DIFFRACTION | 0.243 | 0.212 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
5xp1 | null | E | 0 | null | null | null | null | IMMUNE SYSTEM | 05/31/17 | Structure of monomeric mutant of REI immunoglobulin light chain variable domain crystallized at pH 6 | HOMO SAPIENS | null | homo sapiens | null | Mine, S., Nakamura, T., Uegaki, K., Hamada, D. | 2.88 | X-RAY DIFFRACTION | 0.297 | 0.257 | false | true | null | IGKV1 | Kappa | null | null | null | null | null |
7zfa | M | N | 0 | D | protein | null | spike protein s1 | VIRAL PROTEIN | 04/01/22 | SARS-CoV-2 Omicron RBD in complex with Omi-6 and COVOX-150 Fabs | Homo sapiens; Severe acute respiratory syndrome coronavirus 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Zhou, D., Huo, J., Ren, J., Stuart, D.I. | 4.24 | X-RAY DIFFRACTION | 0.272 | 0.237 | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
5c0s | H | L | 0 | A | protein | null | hemagglutinin, envelope glycoprotein, fibritin fusionprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 06/12/15 | Crystal structure of a generation 4 influenza hemagglutinin stabilized stem in complex with the broadly neutralizing antibody CR6261 | HOMO SAPIENS; INFLUENZA A VIRUS, HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 GROUP M SUBTYPE B, ENTEROBACTERIA PHAGE T4 | homo sapiens | homo sapiens | influenza a virus, human immunodeficiency virustype 1 group m subtype b, enterobacteria phage t4 | Boyington, J.C., Kwong, P.D., Nabel, G.J., Mascola, J.R. | 4.3 | X-RAY DIFFRACTION | 0.310 | 0.238 | false | true | IGHV1 | IGLV1 | Lambda | 0 | -11.068807 | SPR | null | TBD |
4unt | null | F | 0 | null | null | null | null | IMMUNE SYSTEM | 05/30/14 | Induced monomer of the Mcg variable domain | HOMO SAPIENS | null | homo sapiens | null | Brumshtein, B., Esswein, S.R., Landau, M., Ryan, C.M., Whitelegge, J.P., Phillips, M.L., Cascio, D., Sawaya, M.R., Eisenberg, D.S. | 2.7 | X-RAY DIFFRACTION | 0.28925 | 0.24328 | false | true | null | IGLV2 | Lambda | null | null | null | null | null |
4i13 | B | null | 0 | A | protein | null | dihydrofolate reductase | OXIDOREDUCTASE/IMMUNE SYSTEM | 11/19/12 | Nanobody ca1697 binding to the DHFR.folate binary complex | LAMA GLAMA; ESCHERICHIA COLI | lama glama | null | escherichia coli | Oyen, D., Steyaert, J., Barlow, J.N. | 1.6 | X-RAY DIFFRACTION | 0.180 | 0.154 | false | true | IGHV1 | null | null | null | null | null | null | null |
3iu3 | A | B | 0 | K | protein | null | interleukin-2 receptor alpha chain | IMMUNE SYSTEM | 08/29/09 | Crystal structure of the Fab fragment of therapeutic antibody Basiliximab in complex with IL-2Ra (CD25) ectodomain | HOMO SAPIENS; SYNTHETIC CONSTRUCT | null | null | homo sapiens | Du, J., Yang, H., Wang, J., Ding, J. | 2.9 | X-RAY DIFFRACTION | 0.262 | 0.215 | false | true | IGHV1 | IGKV4 | Kappa | 0 | -13.44 | SPR | 25 | 20032294 |
1kxq | G | null | 0 | B | protein | null | alpha-amylase, pancreatic | HYDROLASE, IMMUNE SYSTEM | 02/01/02 | Camelid VHH Domain in Complex with Porcine Pancreatic alpha-Amylase | CAMELUS DROMEDARIUS; SUS SCROFA | camelus dromedarius | null | sus scrofa | Desmyter, A., Spinelli, S., Payan, F., Lauwereys, M., Wyns, L., Muyldermans, S., Cambillau, C. | 1.6 | X-RAY DIFFRACTION | 0.219 | 0.197 | false | true | IGHV1 | null | null | 0 | -11.53 | SPR | null | 11960990 |
4p3c | H | L | 0 | M | peptide | null | matrix metalloproteinase-14 | IMMUNE SYSTEM | 03/06/14 | MT1-MMP:Fab complex (Form I) | MUS MUSCULUS; HOMO SAPIENS | mus musculus | mus musculus | homo sapiens | Rozenberg, H., Udi, Y., Sagi, I. | 1.943 | X-RAY DIFFRACTION | 0.200 | 0.153 | false | true | IGHV5 | IGKV1 | Kappa | null | null | null | null | null |
4khx | H | L | 0 | A | protein | null | gp41 helix | Immune system | 05/01/13 | Crystal structure of gp41 helix complexed with antibody 8062 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Li, M., Gustchina, A,, Wlodawer, A. | 2.921 | X-RAY DIFFRACTION | 0.289 | 0.237 | false | false | IGHV1 | IGLV3 | Lambda | 0 | -11.427933 | ITC | null | TBD |
1ghf | H | L | 0 | null | null | null | null | ANTIBODY FAB FRAGMENT | 11/30/95 | ANTI-ANTI-IDIOTYPE GH1002 FAB FRAGMENT | MUS MUSCULUS | mus musculus | mus musculus | null | Ban, N., Day, J., Wang, X., Ferrone, S., McPherson, A. | 2.7 | X-RAY DIFFRACTION | unknown | 0.210 | false | false | IGHV9 | IGKV10 | Kappa | null | null | null | null | null |
6obe | B | null | 0 | A | protein | null | ricin a chain | TOXIN | 04/01/20 | Ricin A chain bound to VHH antibody V6H8 | RICINUS COMMUNIS; VICUGNA PACOS | vicugna pacos | null | ricinus communis | Rudolph, M.J. | 1.732 | X-RAY DIFFRACTION | 0.208 | 0.171 | false | true | IGHV1 | null | null | null | null | null | null | null |
5npi | A | a | 0 | D | peptide | null | epitope peptide | VIRAL PROTEIN | 04/16/17 | Structure of the Hepatitis C virus strain J4 glycoprotein E2 antigenic region 532-540 bound to the single chain variable fragment of the non-neutralizing antibody DAO5 | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | null | hepatitis c virus | Vasiliauskaite, I., Rey, F.A., Krey, T. | 2.0 | X-RAY DIFFRACTION | 0.217 | 0.197 | true | true | unknown | unknown | unknown | null | null | null | null | null |
7mdu | H | L | 0 | A | protein | null | surface protein gp120 | VIRAL PROTEIN | 04/06/21 | BG505 SOSIP MD39 in complex with the monoclonal antibodies Rh.33104 mAb.1 and RM20A3 | MACACA MULATTA; HUMAN IMMUNODEFICIENCY VIRUS 1 | macaca mulatta | macaca mulatta | human immunodeficiency virus 1 | Antanasijevic, A., Ward, A.B. | 3.3 | ELECTRON MICROSCOPY | null | null | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
5vjq | C | D | 0 | J | protein | null | lysozyme | HYDROLASE/IMMUNE SYSTEM | 04/19/17 | Complex between HyHEL10 Fab fragment heavy chain mutant (I29F, S52T, Y53F) and Pekin duck egg lysozyme isoform I (DEL-I) | MUS MUSCULUS; ANAS PLATYRHYNCHOS | mus musculus | mus musculus | anas platyrhynchos | Langley, D.B., Christ, D. | 1.9 | X-RAY DIFFRACTION | 0.235 | 0.193 | false | true | IGHV3 | IGKV5 | Kappa | null | null | null | null | null |
7ej4 | J | N | 0 | C | protein | null | spike glycoprotein | VIRAL PROTEIN | 04/01/21 | Cryo-EM structure of SARS-CoV-2 spike in complex with a neutralizing antibody RBD-chAb-25 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Yang, T.J., Yu, P.Y., Wu, H.C., Hsu, S.T.D. | 3.6 | ELECTRON MICROSCOPY | null | null | false | true | IGHV5 | IGKV4 | Kappa | null | null | null | null | null |
7dk2 | D | E | 0 | F | protein | null | spike protein s1 | IMMUNE SYSTEM/VIRAL PROTEIN | 11/22/20 | Crystal structure of SARS-CoV-2 Spike RBD in complex with MW07 Fab | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Wang, J., Jiao, S., Wang, R., Zhang, J., Zhang, M., Wang, M., Chen, S. | 3.0 | X-RAY DIFFRACTION | 0.304 | 0.258 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6ws6 | E | F | 0 | null | null | null | null | IMMUNE SYSTEM | 05/27/20 | Structural and functional analysis of a potent sarbecovirus neutralizing antibody | HOMO SAPIENS | homo sapiens | homo sapiens | null | Pinto, D., Park, Y.J., Beltramello, M., Walls, A.C., Tortorici, M.A., Bianchi, S., Jaconi, S., Culap, K., Zatta, F., Marco, A.D., Peter, A., Guarino, B., Spreafico, R., Cameroni, E., Case, J.B., Chen, R.E., Havenar-Daughton, C., Snell, G., Telenti, A., Virgin, H.W., Lanzavecchia, A., Diamond, M.S., Fink, K., Veesler, D... | 3.3 | X-RAY DIFFRACTION | 0.227 | 0.188 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
4xbg | J | K | 0 | null | null | null | null | IMMUNE SYSTEM | 12/16/14 | Crystal structure of human 4E10 Fab in complex with phosphatidic acid (06:0 PA): 2.73 A resolution | HOMO SAPIENS | homo sapiens | homo sapiens | null | Irimia, A., Stanfield, R.L., Wilson, I.A. | 2.73 | X-RAY DIFFRACTION | 0.246 | 0.202 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
6oq5 | F | null | 0 | A | protein | null | toxin b | TOXIN | 04/25/19 | Structure of the full-length Clostridium difficile toxin B in complex with 3 VHHs | CLOSTRIDIOIDES DIFFICILE; CAMELIDAE | camelidae | null | clostridioides difficile | Chen, P., Lam, K., Jin, R. | 3.87 | X-RAY DIFFRACTION | 0.315 | 0.263 | false | true | IGHV1 | null | null | null | null | null | null | null |
7pg8 | I | G | 0 | K | protein | null | ion transport protein,voltage-gated sodium channel | MEMBRANE PROTEIN | 08/13/21 | NaV_Ae1/Sp1CTD_pore-ANT05 complex | HOMO SAPIENS; ALKALILIMNICOLA EHRLICHII MLHE-1; RUEGERIA POMEROYI DSS-3 | homo sapiens | homo sapiens | alkalilimnicola ehrlichii mlhe-1, ruegeriapomeroyi dss-3 | Lolicato, M., Arrigoni, C. | 4.5 | X-RAY DIFFRACTION | 0.352 | 0.303 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6cde | m | n | 0 | c | protein | null | unknown | VIRAL PROTEIN | 02/08/18 | Cryo-EM structure at 3.8 A resolution of vaccine-elicited antibody vFP20.01 in complex with HIV-1 Env BG505 DS-SOSIP, and antibodies VRC03 and PGT122 | HOMO SAPIENS; HUMAN IMMUNODEFICIENCY VIRUS 1 | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Acharya, P., Xu, K., Liu, K., Carragher, B., Potter, C.S., Kwong, P.D. | 3.8 | ELECTRON MICROSCOPY | null | null | false | false | IGHV4 | unknown | unknown | null | null | null | null | null |
3j5m | H | G | 0 | E | protein | null | bg505 sosip gp120 | VIRAL PROTEIN/IMMUNE SYSTEM | 10/26/13 | Cryo-EM structure of the BG505 SOSIP.664 HIV-1 Env trimer with 3 PGV04 Fabs | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Lyumkis, D., Julien, J.-P., Wilson, I.A., Ward, A.B. | 5.8 | ELECTRON MICROSCOPY | null | null | false | true | unknown | unknown | unknown | null | null | null | null | null |
6wty | H | I | 0 | G | protein | null | reticulocyte binding protein 2b | CELL INVASION | 05/04/20 | Plasmodium vivax reticulocyte binding protein 2b (PvRBP2b) bound to human monoclonal antibody 253245 | PLASMODIUM VIVAX (STRAIN SALVADOR I); HOMO SAPIENS | homo sapiens | homo sapiens | plasmodium vivax (strain salvador i) | Chan, L.J., Dietrich, M.H., Tham, W.H. | 3.481 | X-RAY DIFFRACTION | 0.301 | 0.262 | false | true | IGHV1 | IGLV2 | Lambda | null | null | null | null | null |
6zdg | B | C | 0 | A | protein | null | spike glycoprotein | VIRAL PROTEIN | 06/14/20 | Association of three complexes of largely structurally disordered Spike ectodomain with bound EY6A Fab | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Duyvesteyn, H.M.E., Zhou, D., Zhao, Y., Fry, E.E., Ren, J., Stuart, D.I. | 4.7 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
4rau | K | J | 0 | L | protein | null | platelet factor 4 | IMMUNE SYSTEM | 09/11/14 | crystal structure of RTOFab in complex with human PF4 | MUS MUSCULUS; HOMO SAPIENS | mus musculus | mus musculus | homo sapiens | Cai, Z., Zhu, Z., Liu, Q., Greene, M.I. | 3.74 | X-RAY DIFFRACTION | 0.284 | 0.243 | false | true | IGHV5 | IGKV10 | Kappa | null | null | null | null | null |
7nd7 | H | L | 0 | A | protein | null | spike glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 01/30/21 | EM structure of SARS-CoV-2 Spike glycoprotein in complex with COVOX-316 Fab | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Duyvesteyn, H.M.E., Zhao, Y., Ren, J., Stuart, D. | 3.6 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGLV2 | Lambda | null | null | null | null | null |
3oay | H | L | 0 | H | Hapten | BDF | BETA-D-FRUCTOPYRANOSE | IMMUNE SYSTEM | 08/05/10 | A non-self sugar mimic of the HIV glycan shield shows enhanced antigenicity | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Doores, K.J., Fulton, Z., Hong, V., Patel, M.K., Scanlan, C.N., Wormald, M.R., Finn, M.G., Burton, D.R., Wilson, I.A., Davis, B.G | 1.95 | X-RAY DIFFRACTION | 0.223 | 0.182 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
7cws | P | M | 0 | R | protein | null | spike glycoprotein | VIRAL PROTEIN | 08/31/20 | SARS-CoV-2 Spike Proteins Trimer in Complex with FC05 and H014 Fabs Cocktail | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Wang, L., Wang, X. | 3.4 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
7mtb | H | L | 0 | G | protein | null | rhodopsin kinase grk1 | MEMBRANE, Signaling protein/Immune System | 05/13/21 | Rhodopsin kinase (GRK1)-S5E/S488E/T489E in complex with rhodopsin and Fab6 | BOS TAURUS; HOMO SAPIENS | homo sapiens | homo sapiens | bos taurus | Chen, Q., Chen, C.-L., Tesmer, J.J.G. | 4 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
1ngw | B | A | 0 | B | Hapten | MMP | N-METHYLMESOPORPHYRIN | IMMUNE SYSTEM | 12/18/02 | Chimeric Affinity Matured Fab 7g12 complexed with mesoporphyrin | MUS MUSCULUS, HOMO SAPIENS | mus musculus, homo sapiens | mus musculus, homo sapiens | mus musculus, homo sapiens | Yin, J., Andryski, S.E., Beuscher IV, A.E., Stevens, R.C., Schultz, P.G. | 2.6 | X-RAY DIFFRACTION | 0.318 | 0.275 | false | true | IGHV1 | IGKV6 | Kappa | 0 | -10.48 | SPR | null | 12552112 |
4m5z | H | L | 0 | A | protein | null | hemagglutinin ha1 chain | VIRAL PROTEIN/IMMUNE SYSTEM | 08/08/13 | Crystal structure of broadly neutralizing antibody 5J8 bound to 2009 pandemic influenza hemagglutinin, HA1 subunit | HOMO SAPIENS; INFLUENZA A VIRUS | homo sapiens | homo sapiens | influenza a virus | Hong, M., Lee, P.S., Wilson, I.A. | 2.25 | X-RAY DIFFRACTION | 0.238 | 0.191 | false | true | IGHV4 | IGLV3 | Lambda | 0 | -11.324631 | BLI | null | TBD |
1jps | H | L | 0 | T | protein | null | tissue factor | IMMUNE SYSTEM | 08/03/01 | Crystal structure of tissue factor in complex with humanized Fab D3h44 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Faelber, K., Kirchhofer, D., Presta, L., Kelley, R.F., Muller, Y.A. | 1.85 | X-RAY DIFFRACTION | 0.224 | 0.201 | false | true | IGHV3 | IGKV1 | Kappa | 0 | -13.63 | SPR | 25 | 11307801 |
5mvj | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 01/16/17 | Structure of DC8E8 Fab at pH 6.5 crystallized in space-group P1 | MUS MUSCULUS | mus musculus | mus musculus | null | Skrabana, R., Novak, M., Cehlar, O., Kontsekova, E. | 2.5 | X-RAY DIFFRACTION | 0.272 | 0.219 | false | false | IGHV1 | IGKV8 | Kappa | null | null | null | null | null |
4uao | C | B | 0 | A | protein | null | apical merozoite antigen 1 | CELL INVASION | 08/11/14 | Crystal structure of Apical Membrane Antigen 1 from Plasmodium Knowlesi in complex with an invasion inhibitory antibody | PLASMODIUM KNOWLESI; RATTUS NORVEGICUS | rattus norvegicus | rattus norvegicus | plasmodium knowlesi | Vulliez-Le Normand, B., Saul, F.A., Bentley, G.A. | 3.1 | X-RAY DIFFRACTION | 0.266 | 0.188 | false | false | IGHV5 | IGKV14 | Kappa | null | null | null | null | null |
7e8c | M | J | 0 | A | protein | null | 368-2 h | VIRAL PROTEIN | 03/01/21 | SARS-CoV-2 S-6P in complex with 9 Fabs | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Du, S., Xiao, J., Zhang, Z. | 3.16 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV2 | Kappa | null | null | null | null | null |
7ps2 | H | L | 0 | G | protein | null | surface glycoprotein | VIRAL PROTEIN | 09/22/21 | Crystal structure of the receptor binding domain of SARS-CoV-2 beta variant spike glycoprotein in complex with Beta-29 and Beta-53 Fabs | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Zhou, D., Ren, J., Stuart, D.I. | 2.99 | X-RAY DIFFRACTION | 0.266 | 0.233 | false | true | IGHV5 | IGKV3 | Kappa | null | null | null | null | null |
1lk3 | I | M | 0 | B | protein | null | interleukin-10 | IMMUNE SYSTEM | 04/23/02 | ENGINEERED HUMAN INTERLEUKIN-10 MONOMER COMPLEXED TO 9D7 FAB FRAGMENT | HOMO SAPIENS; RATTUS NORVEGICUS | rattus norvegicus | rattus norvegicus | homo sapiens | Josephson, K., Jones, B.C., Walter, L.J., DiGiacomo, R., Indelicato, S.R., Walter, M.R. | 1.91 | X-RAY DIFFRACTION | 0.240 | 0.187 | false | false | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
7ew5 | g | j | 0 | Y | protein | null | major capsid protein l1 | VIRAL PROTEIN | 05/24/21 | immune complex of HPV6 L1 pentamer and neutralizing antibody 13H5 | HUMAN PAPILLOMAVIRUS TYPE 6; MUS MUSCULUS | mus musculus | mus musculus | human papillomavirus type 6 | Wang, Z.P., Wang, D.N., Gu, Y., Li, S.W. | 3.606 | X-RAY DIFFRACTION | 0.293 | 0.252 | false | false | IGHV14 | IGKV6 | Kappa | null | null | null | null | null |
7zfe | M | N | 0 | C | protein | null | spike protein s1 | VIRAL PROTEIN | 04/01/22 | SARS-CoV-2 Omicron RBD in complex with Omi-32 Fab and nanobody C1 | LAMA GLAMA; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Zhou, D., Huo, J., Ren, J., Stuart, D.I. | 3.25 | X-RAY DIFFRACTION | 0.293 | 0.237 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
7p5w | L | null | 0 | F | protein | null | volume-regulated anion channel subunit lrrc8a | MEMBRANE PROTEIN | 07/15/21 | Structure of homomeric LRRC8A Volume-Regulated Anion Channel in complex with synthetic nanobody Sb2 | MUS MUSCULUS; SYNTHETIC CONSTRUCT | synthetic construct | null | mus musculus | Deneka, D., Rutz, S., Sawicka, M. | 3.5 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
2dqi | H | L | 0 | Y | protein | null | lysozyme c | IMMUNE SYSTEM/HYDROLASE | 05/26/06 | Crystal structure of hyhel-10 FV mutant (Ly50a) complexed with hen egg lysozyme | MUS MUSCULUS; GALLUS GALLUS | mus musculus | mus musculus | gallus gallus | Shiroishi, M., Kondo, H., Tsumoto, K., Kumagai, I. | 2.0 | X-RAY DIFFRACTION | 0.257 | 0.218 | false | true | IGHV3 | IGKV5 | Kappa | null | null | null | null | null |
4hj0 | C | D | 0 | B | protein | null | gastric inhibitory polypeptide receptor | IMMUNE SYSTEM | 10/12/12 | Crystal structure of the human GIPr ECD in complex with Gipg013 Fab at 3-A resolution | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Madhurantakam, C., Ravn, P., Gruetter, M.G., Jackson, R.H. | 3.0 | X-RAY DIFFRACTION | 0.311 | 0.255 | false | true | IGHV1 | IGLV1 | Lambda | 0 | -10.420468 | SPR | null | TBD |
3ejz | C | D | 0 | A | protein | null | h(+)/cl(-) exchange transporter clca | IMMUNE SYSTEM/PROTON TRANSPORT | 09/18/08 | Structure of E203V mutant E.coli Cl-/H+ exchanger, CLC-ec1 | ESCHERICHIA COLI; MUS MUSCULUS | mus musculus | mus musculus | escherichia coli | Lim, H.-H., Miller, C. | 2.9 | X-RAY DIFFRACTION | 0.281 | 0.252 | false | false | IGHV4 | IGKV4 | Kappa | null | null | null | null | null |
6xrj | E | F | 0 | null | null | null | null | IMMUNE SYSTEM | 07/13/20 | Crystal structure of the disulfide linked DH717.1 Fab dimer, derived from a macaque HIV-1 vaccine-induced Env glycan-reactive neutralizing antibody B cell lineage | HOMO SAPIENS | homo sapiens | homo sapiens | null | Manne, K., Nicely, N.I., Acharya, P. | 3.15 | X-RAY DIFFRACTION | 0.282 | 0.245 | false | true | IGHV4 | IGLV2 | Lambda | null | null | null | null | null |
4f3f | B | A | 0 | C | protein | null | mesothelin | IMMUNE SYSTEM | 05/09/12 | Crystal Structure of Msln7-64 MORAb-009 FAB complex | HOMO SAPIENS; ESCHERICHIA COLI | null | null | homo sapiens | Xia, D., Pastan, I., Ma, J., Tang, W.K., Esser, L. | 2.65 | X-RAY DIFFRACTION | 0.222 | 0.177 | false | true | IGHV1 | IGKV4 | Kappa | 0 | -12.47283 | SPR | null | TBD |
2h2s | E | F | 0 | B | protein | null | clc cl transporter | ION TRANSPORT | 05/19/06 | Crystal Structure of E148A mutant of CLC-ec1 in SeCN- | ESCHERICHIA COLI; MUS MUSCULUS | mus musculus | mus musculus | escherichia coli | Nguitragool, W., Miller, C. | 3.1 | X-RAY DIFFRACTION | 0.282 | 0.281 | false | false | IGHV4 | IGKV4 | Kappa | null | null | null | null | null |
3csy | E | F | 0 | L | K | protein | protein | NA | NA | envelope glycoprotein gp2 | envelope glycoprotein gp1 | IMMUNE SYSTEM/VIRAL PROTEIN | 04/10/08 | Crystal structure of the trimeric prefusion Ebola virus glycoprotein in complex with a neutralizing antibody from a human survivor | HOMO SAPIENS; ZAIRE EBOLA VIRUS | homo sapiens | homo sapiens | zaire ebola virus | zaire ebola virus | Lee, J.E., Fusco, M.L., Hessell, A.J., Oswald, W.B., Burton, D.R., Saphire, E.O. | 3.4 | X-RAY DIFFRACTION | 0.302 | 0.261 | false | true | IGHV3 | IGKV4 | Kappa | null | null | null | null | null |
5nh3 | I | M | 0 | B | protein | null | activin receptor type-2a | TRANSFERASE | 03/21/17 | CRYSTAL STRUCTURE OF THE Activin receptor type-2A LIGAND BINDING DOMAIN IN COMPLEX WITH BIMAGRUMAB FV | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Scheufler, C. | 2.35 | X-RAY DIFFRACTION | 0.208 | 0.166 | false | false | IGHV1 | IGLV2 | Lambda | 0 | -12.294414 | Unknown | null | TBD |
3fku | U | u | 0 | H | G | protein | protein | NA | NA | hemagglutinin | hemagglutinin | VIRAL PROTEIN/IMMUNE SYSTEM | 12/17/08 | Crystal structure of influenza hemagglutinin (H5) in complex with a broadly neutralizing antibody F10 | INFLUENZA A VIRUS; HOMO SAPIENS | homo sapiens | null | influenza a virus | influenza a virus | Hwang, W.C., Santelli, E., Stec, B., Wei, G., Cadwell, G., Bankston, L.A., Sui, J., Perez, S., Aird, D., Chen, L.M., Ali, M., Murakami, A., Yammanuru, A., Han, T., Cox, N., Donis, R.O., Liddington, R.C., Marasco, W.A. | 3.2 | X-RAY DIFFRACTION | 0.286 | 0.232 | true | true | unknown | unknown | unknown | 0 | -13.48 | SPR | 25 | 19234466 |
7e9g | D | d | 0 | A | B | protein | protein | NA | NA | guanine nucleotide-binding protein g(i) subunit alpha-1 | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | MEMBRANE PROTEIN | 03/04/21 | Cryo-EM structure of Gi-bound metabotropic glutamate receptor mGlu2 | HOMO SAPIENS; LAMA GLAMA | homo sapiens | null | homo sapiens | homo sapiens | Lin, S., Han, S., Zhao, Q., Wu, B. | 3.5 | ELECTRON MICROSCOPY | null | null | true | true | unknown | unknown | unknown | null | null | null | null | null |
7v9l | N | null | 0 | A | Y | B | protein | protein | protein | NA | NA | NA | guanine nucleotide-binding protein g(s) subunit alphaisoforms short | guanine nucleotide-binding protein g(i)/g(s)/g(o) subunitgamma-2 | guanine nucleotide-binding protein g(i)/g(s)/g(t) subunitbeta-1 | STRUCTURAL PROTEIN | 08/26/21 | Cryo-EM structure of the SV1-Gs complex. | HOMO SAPIENS; BOS TAURUS; SYNTHETIC CONSTRUCT; RATTUS NORVEGICUS | synthetic construct | null | homo sapiens | bos taurus | rattus norvegicus | Cong, Z.T., Zhou, F.L., Zhang, C., Zou, X.Y., Zhang, H.B., Wang, Y.Z., Zhou, Q.T., Cai, X.Q., Liu, Q.F., Li, J., Shao, L.J., Mao, C.Y., Wang, X., Wu, J.H., Xia, T., Zhao, L.H., Jiang, H.L., Zhang, Y., Xu, H.E., Cheng, X., Yang, D.H., Wang, M.W. | 2.6 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | null | null | null | null | null | null | null |
2z92 | A | B | 0 | A | Hapten | ENE | (4Z)-2,8:7,12:11,15:14,18:17,22-PENTAANHYDRO-4,5,6,9,10,13,19,20,21-NONADEOXY-D-ARABINO-D-ALLO-D-ALLO-DOCOSA-4,9,20-TRIENITOL | IMMUNE SYSTEM | 09/14/07 | Crystal structure of the Fab fragment of anti-ciguatoxin antibody 10C9 in complex with CTX3C_ABCDE | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Ui, M., Tanaka, Y., Tsumoto, K. | 2.3 | X-RAY DIFFRACTION | 0.269 | 0.228 | false | true | IGHV3 | IGKV4 | Kappa | 0 | -10.85 | ITC | 25 | 18463096 |
4n1e | null | B | 0 | I | protein | null | lysozyme c | Immune system/Hydrolase | 10/04/13 | Structural evidence for antigen receptor evolution | HOMO SAPIENS; GALLUS GALLUS | null | homo sapiens | gallus gallus | Langley, D.B., Rouet, R., Stock, D., Christ, D. | 2.23 | X-RAY DIFFRACTION | 0.265 | 0.223 | false | true | null | IGKV1 | Kappa | null | null | null | null | null |
7ndc | H | L | 0 | B | protein | null | spike glycoprotein | VIRAL PROTEIN, IMMUNE SYSTEM | 01/30/21 | EM structure of SARS-CoV-2 Spike glycoprotein (all RBD down) in complex with COVOX-159 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Duyvesteyn, H.M.E., Zhao, Y., Ren, J., Stuart, D. | 4.1 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
6rcv | J | I | 0 | F | protein | null | reticulocyte binding protein homologue 5 | CELL ADHESION | 04/11/19 | PfRH5 bound to monoclonal antibodies R5.011 and R5.016 | PLASMODIUM FALCIPARUM; HOMO SAPIENS | homo sapiens | homo sapiens | plasmodium falciparum | Alanine, D.W.G., Draper, S.J., Higgins, M.K. | 3.582 | X-RAY DIFFRACTION | 0.305 | 0.280 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
7zfa | H | L | 0 | A | protein | null | spike protein s1 | VIRAL PROTEIN | 04/01/22 | SARS-CoV-2 Omicron RBD in complex with Omi-6 and COVOX-150 Fabs | Homo sapiens; Severe acute respiratory syndrome coronavirus 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Zhou, D., Huo, J., Ren, J., Stuart, D.I. | 4.24 | X-RAY DIFFRACTION | 0.272 | 0.237 | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
5e5m | D | null | 0 | C | protein | null | cytotoxic t-lymphocyte protein 4 | IMMUNE SYSTEM | 10/08/15 | Crystal structure of mouse CTLA-4 in complex with nanobody | MUS MUSCULUS | mus musculus | null | mus musculus | Fedorov, A.A., Fedorov, E.V., Samanta, D., Bonanno, J.B., Almo, S.C. | 2.182 | X-RAY DIFFRACTION | 0.247 | 0.193 | false | true | IGHV1 | null | null | null | null | null | null | null |
5cp3 | H | A | 0 | A | Hapten | YTZ | 4-AMINO-N-(1,3-THIAZOL-2-YL)BENZENESULFONAMIDE | IMMUNE SYSTEM | 07/21/15 | Crystal Structure of an Antigen-Binding Fragment of Monoclonal Antibody against Sulfonamides in Complex with Sulfathiazole | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Wang, Z., Shen, J., Li, C., Li, Y., Wen, K., Yu, X., Zhang, X. | 1.99 | X-RAY DIFFRACTION | 0.266 | 0.214 | false | false | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
7b2q | D | null | 0 | C | B | protein | protein | NA | NA | complement c4 gamma chain | complement c4 alpha chain | IMMUNE SYSTEM | 11/27/20 | Cryo-EM structure of complement C4b in complex with nanobody B12 | LAMA GLAMA; HOMO SAPIENS | lama glama | null | homo sapiens | homo sapiens | Oosterheert, W., De la O Becerra, K.I., Gros, P. | 3.76 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
4hg4 | P | Q | 0 | D | a | protein | protein | NA | NA | hemagglutinin ha2 | unknown | VIRAL PROTEIN/IMMUNE SYSTEM | 10/06/12 | Crystal structure of Fab 2G1 in complex with a H2N2 influenza virus hemagglutinin | INFLUENZA A VIRUS; HOMO SAPIENS | homo sapiens | homo sapiens | influenza a virus | influenza a virus | Xu, R., Wilson, I.A. | 3.2 | X-RAY DIFFRACTION | 0.302 | 0.249 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
6mvl | H | L | 0 | A | protein | null | v-type immunoglobulin domain-containing suppressor of t-cell activation | IMMUNE SYSTEM | 10/26/18 | Crystal structure of VISTA bound to a pH-selective antibody Fab fragment | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Critton, D.A. | 1.61 | X-RAY DIFFRACTION | 0.225 | 0.182 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
4x7f | D | null | 0 | B | protein | null | capsid protein | VIRAL PROTEIN | 12/09/14 | Crystal structure of norovirus GII.10 P domain in complex with Nano-25 | NORWALK VIRUS; VICUGNA PACOS | vicugna pacos | null | norwalk virus | Koromyslova, A.D., Hansman, G.S. | 1.7 | X-RAY DIFFRACTION | 0.187 | 0.160 | false | true | IGHV1 | null | null | 0 | -10.30392 | ITC | null | TBD |
6ev2 | A | B | 0 | A | carbohydrate | BGC | BETA-D-GLUCOSE | IMMUNE SYSTEM | 11/01/17 | Crystal structure of antibody against schizophyllan in complex with laminarihexaose | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Sung, K.H., Josewski, J., Duebel, S., Blankenfeldt, W., Rau, U. | 2.403 | X-RAY DIFFRACTION | 0.233 | 0.194 | false | true | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
5ayu | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 09/04/15 | Crystal structure of HyHEL-10 Fv | MUS MUSCULUS | mus musculus | mus musculus | null | Nakanishi, T., Tsumoto, K., Yokota, A., Kondo, H., Kumagai, I. | 1.8 | X-RAY DIFFRACTION | 0.234 | 0.191 | false | true | IGHV3 | IGKV5 | Kappa | null | null | null | null | null |
7n6p | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 06/08/21 | Crystal structure of the anti-EBOV and SUDV monoclonal antibody 1C3 Fab | HOMO SAPIENS | homo sapiens | homo sapiens | null | Milligan, J.C., Yu, X., Buck, T., Saphire, E.O. | 2.15 | X-RAY DIFFRACTION | 0.231 | 0.175 | false | true | IGHV1 | IGKV4 | Kappa | null | null | null | null | null |
4yhp | E | F | 0 | null | null | null | null | IMMUNE SYSTEM | 02/27/15 | Crystal structure of 309M3-B Fab in complex with H3K9me3 peptide | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | null | Hattori, T., Dementieva, I.S., Montano, S.P., Koide, S. | 2.53 | X-RAY DIFFRACTION | 0.250 | 0.211 | false | true | IGHV3 | IGLV3 | Lambda | 0 | -11.867518 | Unknown | null | TBD |
5k9q | U | V | 0 | P | Q | protein | protein | NA | NA | hemagglutinin ha2 | hemagglutinin ha1 | IMMUNE SYSTEM | 06/01/16 | Crystal structure of multidonor HV1-18-class broadly neutralizing Influenza A antibody 16.a.26 in complex with A/Hong Kong/1-4-MA21-1/1968 (H3N2) Hemagglutinin | INFLUENZA A VIRUS; INFLUENZA A VIRUS (STRAIN A/HONG KONG/1/1968 H3N2); HOMO SAPIENS | homo sapiens | homo sapiens | influenza a virus (strain a/hong kong/1/1968h3n2) | influenza a virus | Joyce, M.G., Thomas, P.V., Wheatley, A.K., McDermott, A.B., Mascola, J.R., Kwong, P.D. | 2.503 | X-RAY DIFFRACTION | 0.218 | 0.182 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
5y9f | P | O | 0 | C | protein | null | light chains of fab fragment of antibody 28f10 | VIRAL PROTEIN/IMMUNE SYSTEM | 08/24/17 | Crystal structure of HPV59 pentamer in complex with the Fab fragment of antibody 28F10 | HUMAN PAPILLOMAVIRUS TYPE 59; MUS MUSCULUS | mus musculus | mus musculus | human papillomavirus type 59 | Li, S.W., Li, Z.H. | 3.35 | X-RAY DIFFRACTION | 0.261 | 0.230 | false | false | IGHV5 | IGKV1 | Kappa | null | null | null | null | null |
5i15 | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 02/05/16 | CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV1-69/IGKV1-39 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Teplyakov, A., Obmolova, G., Malia, T., Luo, J., Gilliland, G. | 2.6 | X-RAY DIFFRACTION | 0.241 | 0.205 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
7bud | G | I | 0 | B | protein | null | dengue virus serotype 2 e protein | VIRUS | 04/06/20 | Cryo-EM structure of Dengue virus serotype 2 complexed with Fab SIgN-3C at pH 8.0 | HOMO SAPIENS; DENGUE VIRUS 2 | homo sapiens | homo sapiens | dengue virus 2 | Zhang, S., Chew, S.V., Lim, X.N., Ng, T.S., Kostyuchenko, V.A., Lok, S.M. | 4.5 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
4krm | F | null | 0 | E | protein | null | epidermal growth factor receptor | TRANSFERASE/IMMUNE SYSTEM | 05/16/13 | Nanobody/VHH domain 7D12 in complex with domain III of the extracellular region of EGFR, pH 3.5 | LAMA GLAMA; HOMO SAPIENS | lama glama | null | homo sapiens | Ferguson, K.M., Schmitz, K.R. | 2.655 | X-RAY DIFFRACTION | 0.244 | 0.208 | false | true | IGHV1 | null | null | null | null | null | null | null |
5wtg | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 12/11/16 | Crystal structure of the Fab fragment of anti-HAV antibody R10 | MUS MUSCULUS | mus musculus | mus musculus | null | Wang, X., Zhu, L., Dang, M., Hu, Z., Gao, Q., Yuan, S., Sun, Y., Zhang, B., Ren, J., Walter, T.S., Wang, J., Fry, E.E., Stuart, D.I., Rao, Z. | 2.907 | X-RAY DIFFRACTION | 0.266 | 0.201 | false | false | IGHV5 | IGKV4 | Kappa | null | null | null | null | null |
7czu | H | K | 0 | A | protein | null | spike glycoprotein | VIRAL PROTEIN | 09/09/20 | S protein of SARS-CoV-2 in complex bound with P5A-1B6_2B | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Yan, R.H., Zhang, Y.Y., Li, Y.N., Zhou, Q. | 3.4 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6z3p | H | L | 0 | C | A | B | protein | protein | protein | NA | NA | NA | vp3 | vp1 | vp2 | VIRUS | 05/21/20 | Structure of EV71 in complex with a protective antibody 38-3-11A Fab | HOMO SAPIENS; ENTEROVIRUS A71 | homo sapiens | homo sapiens | enterovirus a71 | enterovirus a71 | enterovirus a71 | Zhou, D., Fry, E.E., Ren, J., Stuart, D.I. | 2.8 | ELECTRON MICROSCOPY | null | null | false | true | IGHV5 | IGKV1 | Kappa | null | null | null | null | null |
4zs6 | C | D | 0 | B | protein | null | s protein | IMMUNE SYSTEM | 05/13/15 | Receptor binding domain and Fab complex | HOMO SAPIENS; MIDDLE EAST RESPIRATORY SYNDROME CORONAVIRUS | homo sapiens | homo sapiens | middle east respiratory syndrome coronavirus | Yu, X., Wang, X. | 3.166 | X-RAY DIFFRACTION | 0.245 | 0.203 | false | true | IGHV3 | IGKV1 | Kappa | 0 | -8.875561 | SPR | null | TBD |
3rif | H | L | 0 | A | protein | null | avermectin-sensitive glutamate-gated chloride channel gluclalpha | transport protein/immune system | 04/13/11 | C. elegans glutamate-gated chloride channel (GluCl) in complex with Fab, ivermectin and glutamate. | CAENORHABDITIS ELEGANS; MUS MUSCULUS | mus musculus | mus musculus | caenorhabditis elegans | Hibbs, R.E., Gouaux, E. | 3.345 | X-RAY DIFFRACTION | 0.271 | 0.248 | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
2ok0 | H | L | 0 | D | nucleic-acid | null | 5'-d(*tp*c)-3' | IMMUNE SYSTEM/DNA | 01/15/07 | Fab ED10-DNA complex | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | null | Stanfield, R.L., Sanguineti, S., Wilson, I.A., de Prat-Gay, G. | 1.89 | X-RAY DIFFRACTION | 0.204 | 0.177 | false | false | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
7sc1 | P | Q | 0 | C | protein | null | spike glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 09/26/21 | Structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment, R40-1G8 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Fan, C., Bjorkman, P.J. | 3.2 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6srx | I | M | 0 | null | null | null | null | PROTEIN BINDING | 09/06/19 | Structure of the arginase-2-inhibitory human antigen-binding fragment Fab C0021158 | HOMO SAPIENS | null | null | null | Burschowsky, D., Addyman, A., Fiedler, S., Groves, M., Haynes, S., Seewooruthun, C., Carr, M. | 1.9 | X-RAY DIFFRACTION | 0.261 | 0.234 | false | false | IGHV3 | IGLV1 | Lambda | null | null | null | null | null |
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