pdb stringlengths 4 4 | Hchain stringclasses 59
values | Lchain stringclasses 60
values | model int64 0 76 | antigen_chain stringclasses 386
values | antigen_type stringclasses 24
values | antigen_het_name stringclasses 240
values | antigen_name stringlengths 1 396 ⌀ | short_header stringclasses 448
values | date stringlengths 8 8 | compound stringlengths 4 243 | organism stringlengths 3 175 ⌀ | heavy_species stringclasses 121
values | light_species stringclasses 67
values | antigen_species stringclasses 937
values | authors stringlengths 6 762 | resolution stringlengths 1 8 | method stringclasses 10
values | r_free stringclasses 354
values | r_factor stringclasses 342
values | scfv bool 2
classes | engineered bool 2
classes | heavy_subclass stringclasses 14
values | light_subclass stringclasses 35
values | light_ctype stringclasses 3
values | affinity float64 0 0 ⌀ | delta_g float64 -16.91 -5.04 ⌀ | affinity_method stringclasses 11
values | temperature float64 4 37 ⌀ | pmid stringclasses 157
values |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
6x07 | B | null | 0 | A | protein | null | nucleoporin nic96 | STRUCTURAL PROTEIN | 05/15/20 | Nic96 from S. cerevisiae bound by VHH-SAN12 | SACCHAROMYCES CEREVISIAE (STRAIN ATCC 204508 / S288C); VICUGNA PACOS | vicugna pacos | null | saccharomyces cerevisiae (strain atcc 204508 /s288c) | Andersen, K., Nordeen, S.A., Schwartz, T.U. | 2.1 | X-RAY DIFFRACTION | 0.245 | 0.227 | false | true | IGHV1 | null | null | null | null | null | null | null |
4fze | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 07/06/12 | Crystal structure of N26_i1 Fab, an ADCC mediating anti-HIV-1 antibody. | HOMO SAPIENS | homo sapiens | homo sapiens | null | Tolbert, W.D., Wu, X., Pazgier, M. | 1.999 | X-RAY DIFFRACTION | 0.245 | 0.186 | false | true | IGHV1 | IGLV3 | Lambda | null | null | null | null | null |
3nps | B | C | 0 | A | protein | null | suppressor of tumorigenicity 14 protein | HYDROLASE/IMMUNE SYSTEM | 06/29/10 | Crystal structure of membrane-type serine protease 1 (MT-SP1) in complex with the Fab Inhibitor S4 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Baharuddin, A. | 1.5 | X-RAY DIFFRACTION | 0.228 | 0.188 | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
7e9g | E | null | 0 | R | protein | null | metabotropic glutamate receptor 2 | MEMBRANE PROTEIN | 03/04/21 | Cryo-EM structure of Gi-bound metabotropic glutamate receptor mGlu2 | HOMO SAPIENS; LAMA GLAMA | lama glama | null | homo sapiens | Lin, S., Han, S., Zhao, Q., Wu, B. | 3.5 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
5dd5 | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 08/24/15 | Crystal structures in an anti-HIV antibody lineage from immunization of Rhesus macaques | MACACA MULATTA | macaca mulatta | macaca mulatta | null | Nicely, N.I., Pemble IV, C.W., Haynes, B.F. | 1.9 | X-RAY DIFFRACTION | 0.261 | 0.198 | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
7l8p | E | F | 0 | C | protein | null | isoform 3 of integrin alpha-iib | CELL ADHESION | 12/31/20 | Integrin alphaIIbbeta3 in complex with sibrafiban | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | Lin, F.-Y., Springer, T.A. | 2.34995 | X-RAY DIFFRACTION | 0.245 | 0.204 | false | true | IGHV14 | IGKV14 | Kappa | null | null | null | null | null |
2kqn | null | B | 4 | null | null | null | null | IMMUNE SYSTEM | 11/11/09 | Solution structure of the AL-09 H87Y immunoglobulin light chain variable domain | HOMO SAPIENS | null | homo sapiens | null | Volkman, B.F., Peterson, F.C., Ramirez-Alvarado, M., Baden, E.M. | NOT | SOLUTION NMR | null | null | false | true | null | IGKV1 | Kappa | null | null | null | null | null |
7oo2 | C | D | 0 | null | null | null | null | ANTIMICROBIAL PROTEIN | 05/26/21 | Crystal structure of an antibody targeting the capsular polysaccharide of serogroup X Neisseria meningitidis (MenX) | MUS MUSCULUS | mus musculus | mus musculus | null | Pietri, G.P., de Ruyck, J., Lenac, T., Adamo, R., Bouckaert, J. | 2.16 | X-RAY DIFFRACTION | 0.262 | 0.213 | false | true | IGHV2 | IGKV17 | Kappa | null | null | null | null | null |
7ndf | C | null | 0 | B | protein | null | lipid a abc transporter atp-binding protein/permease msba | PROTEIN BINDING | 02/01/21 | Crystal structure of nanobody Nb_MsbA#1 in complex with the nucleotide binding domain of MsbA | VICUGNA PACOS; ESCHERICHIA COLI | vicugna pacos | null | escherichia coli | Meier, G., Seeger, M. | 2.1 | X-RAY DIFFRACTION | 0.244 | 0.205 | false | true | IGHV1 | null | null | null | null | null | null | null |
1s78 | F | E | 0 | B | protein | null | receptor protein-tyrosine kinase erbb-2 | TRANSFERASE | 01/29/04 | Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | Franklin, M.C., Carey, K.D., Vajdos, F.F., Leahy, D.J., de Vos, A.M., Sliwkowski, M.X. | 3.25 | X-RAY DIFFRACTION | 0.268 | 0.224 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6fyu | I | null | 0 | H | G | protein | protein | NA | NA | hemagglutinin | hemagglutinin | VIRAL PROTEIN | 03/12/18 | Structure of H7(A/Shanghai/2/2013) Influenza Hemagglutinin in complex SD36 | INFLUENZA A VIRUS; LAMA GLAMA | lama glama | null | influenza a virus | influenza a virus | Laursen, N.S., Wilson, I.A. | 2.643 | X-RAY DIFFRACTION | 0.216 | 0.186 | false | true | IGHV1 | null | null | null | null | null | null | null |
6edu | L | M | 0 | D | I | protein | protein | NA | NA | envelope glycoprotein gp160 | t-cell surface glycoprotein cd4 | IMMUNE SYSTEM | 08/11/18 | B41 SOSIP.664 in complex with soluble CD4 (D1-D2), the co-receptor mimicking antibody 21c and the broadly neutralizing antibody 8ANC195 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | homo sapiens | Barnes, C.O., Bjorkman, P.J. | 4.06 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
5yd4 | G | g | 0 | H | peptide | null | epitope peptide (mutation t6a) | IMMUNE SYSTEM | 09/11/17 | Crystal structure of the scFv antibody 4B08 with epitope peptide (mutation T6A) | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | null | homo sapiens | Caaveiro, J.M.M., Miyanabe, K., Tsumoto, K. | 1.35 | X-RAY DIFFRACTION | 0.173 | 0.135 | true | true | unknown | unknown | unknown | null | null | null | null | null |
6k64 | null | A | 0 | C | protein | null | protein a | STRUCTURAL PROTEIN | 06/01/19 | Application of anti-helix antibodies in protein structure determination (8188-3LRH) | HOMO SAPIENS; STAPHYLOCOCCUS AUREUS SUBSP. AUREUS | null | homo sapiens | staphylococcus aureus subsp. aureus | Lee, J.O., Jin, M.S., Kim, J.W., Kim, S., Lee, H., Cho, G.Y. | 1.933 | X-RAY DIFFRACTION | 0.207 | 0.171 | false | true | null | IGLV1 | Lambda | null | null | null | null | null |
6b7z | E | F | 0 | B | protein | null | insulin-degrading enzyme | HYDROLASE/IMMUNE SYSTEM | 10/05/17 | Cryo-EM structure of human insulin degrading enzyme in complex with FAB H11 heavy chain and FAB H11 light chain | HOMO SAPIENS; MUS MUSCULUS | mus musculus, homo sapiens | mus musculus, homo sapiens | homo sapiens | Liang, W.G., Zhang, Z., Bailey, L.J., Kossiakoff, A.A., Tan, Y.Z., Wei, H., Carragher, B., Potter, S.C., Tang, W.J. | 6.5 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
7ter | M | N | 0 | D | C | protein | protein | NA | NA | glutamate receptor ionotropic, nmda 2b | glutamate receptor ionotropic, nmda 1 | SIGNALING PROTEIN/IMMUNE SYSTEM | 01/05/22 | Cryo-EM structure of GluN1b-2B NMDAR in complex with Fab5 non-active2 conformation | RATTUS NORVEGICUS; MUS MUSCULUS | mus musculus | mus musculus | rattus norvegicus | rattus norvegicus | Tajima, N., Furukawa, H. | 5.23 | ELECTRON MICROSCOPY | null | null | false | false | IGHV5 | IGKV3 | Kappa | null | null | null | null | null |
7f35 | F | E | 0 | E | Hapten | GFN | 1-cyclopropyl-6-fluoro-8-methoxy-7-[(3S)-3-methylpiperazin-1-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid | IMMUNE SYSTEM | 06/15/21 | Crystal structure of anti S-gatifloxacin antibody Fab fragment in complex with S-gatifloxacin | MUS MUSCULUS | mus musculus | mus musculus | mus musculus | Wang, L.T., Jiao, W.Y., Shen, X., Lei, H.T. | 2.6 | X-RAY DIFFRACTION | 0.235 | 0.200 | false | false | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
4m1g | H | L | 0 | B | A | protein | protein | NA | NA | a33r | a33r | IMMUNE SYSTEM | 08/02/13 | Structure of murine IgG2a A27D7-Fab in complex with vaccinia antigen A33R at the resolution of 1.6 Angstroms | MUS MUSCULUS; VACCINIA VIRUS | mus musculus | mus musculus | vaccinia virus | vaccinia virus | Matho, M.H., Schlossman, A.M., Zajonc, D.M. | 1.6 | X-RAY DIFFRACTION | 0.226 | 0.201 | false | true | IGHV2 | IGKV4 | Kappa | 0 | -10.697908 | SPR | null | TBD |
6qgy | B | null | 0 | A | protein | null | outer membrane protein assembly factor bama | MEMBRANE PROTEIN | 01/14/19 | Crystal structure of E.coli BamA beta-barrel in complex with nanobody B12 | ESCHERICHIA COLI O157:H7; LAMA GLAMA | lama glama | null | escherichia coli o157 | Hartmann, J.-B., Kaur, H., Jakob, R.P., Zahn, M., Zimmermann, I., Seeger, M., Maier, T., Hiller, S. | 2.509 | X-RAY DIFFRACTION | 0.244 | 0.222 | false | true | IGHV1 | null | null | null | null | null | null | null |
5aum | A | B | 0 | D | peptide | null | peptide renlyfqgkdg | IMMUNE SYSTEM/PEPTIDE | 04/30/15 | Crystal structure of a Fab fragment with the ligand peptide | RATTUS; SYNTHETIC CONSTRUCT | rattus | rattus | potyviridae | Kitago, Y., Takagi, J. | 2.05 | X-RAY DIFFRACTION | 0.221 | 0.189 | false | true | IGHV10 | IGKV2 | Kappa | null | null | null | null | null |
6kyz | B | C | 0 | A | protein | null | genome polyprotein | VIRAL PROTEIN | 05/27/20 | HRV14 3C in complex with single chain antibody YDF | HUMAN RHINOVIRUS 14; HOMO SAPIENS | homo sapiens | homo sapiens | human rhinovirus 14 | Meng, B., Yang, B., Wilson, I.A. | 1.845 | X-RAY DIFFRACTION | 0.208 | 0.175 | false | true | IGHV3 | IGLV3 | Lambda | null | null | null | null | null |
4hij | B | A | 0 | B | carbohydrate | RAM | polysaccharide | IMMUNE SYSTEM | 10/11/12 | Anti-Streptococcus pneumoniae 23F Fab 023.102 with bound L-rhamnose-(1-2)-alpha-D-galactose-(3-O)-phosphate-2-glycerol | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Bryson, S., Risnes, L., Damgupta, S., Thomson, C.A., Schrader, J.W., Pai, E.F. | 2.1 | X-RAY DIFFRACTION | 0.262 | 0.249 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
7jn5 | H | L | 0 | F | protein | null | spike glycoprotein | Viral protein/IMMUNE SYSTEM | 08/03/20 | Crystal structure of SARS-CoV receptor binding domain in complex with human antibody CR3022 | HOMO SAPIENS; HUMAN SARS CORONAVIRUS | homo sapiens | homo sapiens | human sars coronavirus | Wu, N.C., Yuan, M., Zhu, X., Wilson, I.A. | 2.705 | X-RAY DIFFRACTION | 0.272 | 0.211 | false | true | IGHV5 | IGKV4 | Kappa | null | null | null | null | null |
7zxu | A | null | 0 | E | protein | null | spike protein s1 | VIRAL PROTEIN | 05/23/22 | SARS-CoV-2 Omicron BA.4/5 RBD in complex with Beta-27 Fab and C1 nanobody | Homo sapiens; Lama glama; Severe acute respiratory syndrome coronavirus 2 | lama glama | null | severe acute respiratory syndrome coronavirus2 | Huo, J., Zhou, D., Ren, J., Stuart, D.I. | 1.89 | X-RAY DIFFRACTION | 0.209 | 0.181 | false | true | IGHV1 | null | null | null | null | null | null | null |
7qf1 | C | B | 0 | A | protein | null | spike protein s1 | VIRAL PROTEIN | 12/03/21 | Crystal structure of the SARS-CoV-2 RBD in complex with the human antibody CV2.6264 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Fernandez, I., Pederzoli, R., Rey, F.A. | 2.8 | X-RAY DIFFRACTION | 0.254 | 0.229 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
6rnk | B | null | 0 | A | protein | null | succinate receptor 1 | MEMBRANE PROTEIN | 05/08/19 | Crystal structure of a humanized (K18E, K269N) rat succinate receptor SUCNR1 (GPR91) in complex with a nanobody and antagonist NF-56-EJ40. | RATTUS NORVEGICUS; VICUGNA PACOS | vicugna pacos | null | rattus norvegicus | Haffke, M., Jaakola, V.-P. | 1.94 | X-RAY DIFFRACTION | 0.199 | 0.177 | false | true | IGHV1 | null | null | null | null | null | null | null |
5wym | A | a | 0 | null | null | null | null | IMMUNE SYSTEM | 01/13/17 | Crystal structure of an anti-connexin26 scFv | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens, synthetic construct | null | null | Li, S., Xu, L. | 2.65 | X-RAY DIFFRACTION | 0.263 | 0.236 | true | true | unknown | unknown | unknown | null | null | null | null | null |
2vdo | H | L | 0 | A | protein | null | integrin alpha-iib | CELL ADHESION/IMMUNE SYSTEM | 10/10/07 | Integrin AlphaIIbBeta3 Headpiece Bound to Fibrinogen Gamma chain peptide, HHLGGAKQAGDV | HOMO SAPIENS; MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | homo sapiens | Springer, T., Zhu, J., Xiao, T. | 2.51 | X-RAY DIFFRACTION | 0.190 | 0.148 | false | false | IGHV14 | IGKV14 | Kappa | null | null | null | null | null |
6ssi | H | null | 0 | C | protein | null | cys-loop ligand-gated ion channel | TRANSPORT PROTEIN | 09/07/19 | Structure of the pentameric ligand-gated ion channel ELIC in complex with a PAM nanobody | DICKEYA CHRYSANTHEMI; LAMA GLAMA | lama glama | null | dickeya chrysanthemi | Ulens, C., Brams, M., Evans, G.L., Spurny, R., Govaerts, C., Pardon, E., Steyaert, J. | 2.59 | X-RAY DIFFRACTION | 0.246 | 0.230 | false | true | IGHV1 | null | null | null | null | null | null | null |
6mu3 | H | L | 0 | H | carbohydrate | BMA | polysaccharide | IMMUNE SYSTEM | 10/22/18 | Anti-HIV-1 Fab 2G12 + Man7 re-refinement | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Wilson, I.A., Calarese, D.A., Stanfield, R.L. | 2.327 | X-RAY DIFFRACTION | 0.235 | 0.201 | false | true | unknown | IGKV1 | Kappa | 0.000001 | -8.396789 | Unknown | null | TBD |
5uk4 | m | null | 0 | M | protein | null | anti-vesicular stomatitis virus n vhh | Viral Protein/RNA/Immune System | 01/19/17 | VESICULAR STOMATITS VIRUS N PROTEIN IN COMPLEX WITH INHIBITORY NANOBODY 1307 | VESICULAR STOMATITIS INDIANA VIRUS (STRAIN SAN JUAN); VICUGNA PACOS | vicugna pacos | null | vesicular stomatitis indiana virus (strain sanjuan) | Hanke, L., Knockenhauer, K.E., Ploegh, H.L., Schwartz, T.U. | 3.204 | X-RAY DIFFRACTION | 0.288 | 0.237 | false | false | IGHV1 | null | null | null | null | null | null | null |
6k2i | A | null | 19 | null | null | null | null | AFB1-BINDING PROTEIN | 05/14/19 | Solution structure of camelid nanobody Nb11 against aflatoxin B1 | VICUGNA PACOS | vicugna pacos | null | null | Nie, Y., Li, S.L., He, T., Zhu, J., Yang, Y.H. | NOT | SOLUTION NMR | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
7oay | L | null | 0 | K | protein | null | unknown | ANTIVIRAL PROTEIN | 04/20/21 | Nanobody F2 bound to RBD | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; LAMA GLAMA | null | null | null | Naismith, J.H., Mikolajek, H. | 2.34 | X-RAY DIFFRACTION | 0.228 | 0.192 | false | false | IGHV1 | null | null | null | null | null | null | null |
6by3 | A | B | 0 | C | protein | null | ph-gated potassium channel kcsa | MEMBRANE PROTEIN | 12/19/17 | Open and conductive conformation of KcsA-T75A mutant | MUS MUSCULUS; STREPTOMYCES COELICOLOR | mus musculus | mus musculus | streptomyces coelicolor | Labro, A.J., Cortes, D.M., Tilegenova, C., Cuello, L.G. | 2.37 | X-RAY DIFFRACTION | 0.219 | 0.205 | false | true | IGHV1 | IGKV5 | Kappa | null | null | null | null | null |
4xi5 | D | C | 0 | B | A | protein | protein | NA | NA | envelope glycoprotein l | envelope glycoprotein h | Viral Protein/Immune System | 01/06/15 | gHgL of varicella-zoster virus in complex with human neutralizing antibodies | HUMAN HERPESVIRUS 3 STRAIN OKA VACCINE; HOMO SAPIENS | homo sapiens | homo sapiens | human herpesvirus 3 strain oka vaccine | human herpesvirus 3 strain oka vaccine | Xing, Y. | 3.9 | X-RAY DIFFRACTION | 0.276 | 0.245 | false | true | IGHV3 | IGKV1 | Kappa | 0 | -12.700845 | SPR | null | TBD |
7mzk | F | E | 0 | A | protein | null | spike protein s1 | VIRAL PROTEIN | 05/24/21 | SARS-CoV-2 receptor binding domain bound to Fab WCSL 129 and Fab PDI 96 | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Pymm, P., Dietrich, M.H., Tan, L.L., Chan, L.J., Tham, W.H. | 2.25 | X-RAY DIFFRACTION | 0.235 | 0.197 | false | true | IGHV3 | IGLV1 | Lambda | null | null | null | null | null |
7nj3 | F | null | 0 | A | protein | null | polymerase acidic protein | VIRAL PROTEIN | 02/15/21 | 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8196 core | INFLUENZA A VIRUS (STRAIN A/BREVIG MISSION/1/1918 H1N1); STAPHYLOCOCCUS AUREUS; CAMELIDAE MIXED LIBRARY; SYNTHETIC CONSTRUCT | camelidae mixed library | null | influenza a virus (strain a/brevigmission/1/1918 h1n1) | Keown, J.R., Carrique, L., Fodor, E., Grimes, J.M. | 4.48 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
5k9o | H | L | 0 | I | protein | null | hemagglutinin | IMMUNE SYSTEM | 06/01/16 | Crystal structure of multidonor HV6-1-class broadly neutralizing Influenza A antibody 31.b.09 in complex with Hemagglutinin H1 A/California/04/2009. | INFLUENZA A VIRUS (STRAIN SWL A/CALIFORNIA/04/2009 H1N1); HOMO SAPIENS | homo sapiens | homo sapiens | influenza a virus (strain swla/california/04/2009 h1n1) | Joyce, M.G., Thomas, P.V., Wheatley, A.K., McDermott, A.B., Mascola, J.R., Kwong, P.D. | 3.387 | X-RAY DIFFRACTION | 0.346 | 0.291 | false | true | IGHV1 | IGKV2 | Kappa | null | null | null | null | null |
3iy3 | B | A | 0 | null | null | null | null | IMMUNE SYSTEM | 04/09/09 | Variable domains of the computer generated model (WAM) of Fab 8 fitted into the cryoEM reconstruction of the virus-Fab 8 complex | MUS MUSCULUS | mus musculus | mus musculus | null | Hafenstein, S., Bowman, V.D., Sun, T., Nelson, C.D., Palermo, L.M., Chipman, P.R., Battisti, A.J., Parrish, C.R., Rossmann, M.G. | 11.1 | ELECTRON MICROSCOPY | null | null | false | false | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
3rpi | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 04/26/11 | Crystal Structure of Fab from 3BNC60, Highly Potent anti-HIV Antibody | HOMO SAPIENS | homo sapiens | homo sapiens | null | Diskin, R., Bjorkman, P.J. | 2.648 | X-RAY DIFFRACTION | 0.258 | 0.208 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
7zr7 | D | E | 0 | A | protein | null | spike glycoprotein,fibritin | STRUCTURAL PROTEIN | 05/03/22 | OMI-42 FAB IN COMPLEX WITH SARS-COV-2 BETA SPIKE GLYCOPROTEIN | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; TEQUATROVIRUS T4; HOMO SAPIENS | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2, tequatrovirus t4 | Duyvesteyn, H.M.E., Ren, J., Stuart, D.I. | 3.7 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGLV2 | Lambda | null | null | null | null | null |
6e9q | C | D | 0 | null | null | null | null | IMMUNE SYSTEM | 05/01/19 | The crystal structure of bovine ultralong antibody BOV-6 | BOS TAURUS | bos taurus | bos taurus | null | Dong, J., Crowe, J.E. | 3.4 | X-RAY DIFFRACTION | 0.311 | 0.254 | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
4n1e | null | C | 0 | J | protein | null | lysozyme c | Immune system/Hydrolase | 10/04/13 | Structural evidence for antigen receptor evolution | HOMO SAPIENS; GALLUS GALLUS | null | homo sapiens | gallus gallus | Langley, D.B., Rouet, R., Stock, D., Christ, D. | 2.23 | X-RAY DIFFRACTION | 0.265 | 0.223 | false | true | null | IGKV1 | Kappa | null | null | null | null | null |
5vj6 | Q | R | 0 | C | F | protein | protein | NA | NA | envelope glycoprotein gp160 | envelope glycoprotein gp160 | VIRAL PROTEIN/IMMUNE SYSTEM | 04/18/17 | BG505 SOSIP.664 in complex with broadly neutralizing antibodies PG9 and 8ANC195 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | human immunodeficiency virus 1 | Wang, H., Bjorkman, P.J. | 11.5 | ELECTRON MICROSCOPY | null | null | false | true | unknown | IGKV1 | Kappa | null | null | null | null | null |
5ukb | e | null | 0 | E | protein | null | nucleocapsid | Viral Protein/RNA/Immune System | 01/20/17 | VSV N PROTEIN IN COMPLEX WITH INHIBITORY NANOBODY 1004 | ESCHERICHIA COLI; VESICULAR STOMATITIS INDIANA VIRUS; VICUGNA PACOS | vicugna pacos | null | vesicular stomatitis indiana virus | Hanke, L., Knockenhauer, K.E., Ploegh, H.L., Schwartz, T.U. | 5.473 | X-RAY DIFFRACTION | 0.338 | 0.336 | false | false | IGHV1 | null | null | null | null | null | null | null |
1vhp | A | null | 8 | null | null | null | null | IMMUNOGLOBULIN | 04/16/96 | VH-P8, NMR | HOMO SAPIENS | homo sapiens | null | null | Riechmann, L. | NOT | SOLUTION NMR | null | null | false | true | unknown | unknown | unknown | null | null | null | null | null |
7wpe | X | Y | 0 | B | protein | null | spike glycoprotein | VIRAL PROTEIN | 01/23/22 | SARS-CoV-2 Omicron Variant S Trimer complexed with two JMB2002 Fab | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; MUS MUSCULUS; LAMA GLAMA | mus musculus | mus musculus | severe acute respiratory syndrome coronavirus2 | Yin, W., Xu, Y., Xu, P., Cao, X., Wu, C., Gu, C., He, X., Wang, X., Huang, S., Yuan, Q., Wu, K., Hu, W., Huang, Z., Liu, J., Wang, Z., Jia, F., Xia, K., Liu, P., Wang, X., Song, B., Zheng, J., Jiang, H., Cheng, X., Jiang, Y., Deng, S.J., Xu, H.E. | 2.69 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
5dwu | H | L | 0 | A | B | protein | protein | NA | NA | cytokine receptor common subunit beta | cytokine receptor common subunit beta | IMMUNE SYSTEM | 09/23/15 | Beta common receptor in complex with a Fab | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | homo sapiens | Dhagat, U., Parker, M.W. | 3.97 | X-RAY DIFFRACTION | 0.330 | 0.289 | false | true | IGHV3 | IGKV1 | Kappa | 0 | -9.972357 | SPR | null | TBD |
3n85 | H | L | 0 | A | protein | null | receptor tyrosine-protein kinase erbb-2 | Transferase/immune system | 05/27/10 | Crystallographic trimer of HER2 extracellular regions in complex with tryptophan-rich antibody fragment | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Eigenbrot, C. | 3.2 | X-RAY DIFFRACTION | 0.230 | 0.206 | false | true | IGHV3 | IGKV1 | Kappa | 0 | -12.41 | SPR | null | 20654626 |
3uaj | C | D | 0 | B | protein | null | envelope protein | VIRAL PROTEIN/IMMUNE SYSTEM | 10/21/11 | Crystal structure of the envelope glycoprotein ectodomain from dengue virus serotype 4 in complex with the fab fragment of the chimpanzee monoclonal antibody 5H2 | DENGUE VIRUS 4; PAN TROGLODYTES | pan troglodytes | pan troglodytes | dengue virus 4 | Cockburn, J.J.B., Stura, E.A., Navarro-Sanchez, M.E., Rey, F.A. | 3.232 | X-RAY DIFFRACTION | 0.246 | 0.241 | false | true | IGHV4 | IGKV1 | Kappa | 0 | -11.647373 | Unknown | null | TBD |
2ltq | C | B | 2 | A | protein | null | disulfide bond formation protein b | MEMBRANE PROTEIN, OXIDOREDUCTASE | 05/30/12 | High resolution structure of DsbB C41S by joint calculation with solid-state NMR and X-ray data | ESCHERICHIA COLI; MUS MUSCULUS | mus musculus | mus musculus | escherichia coli | Tang, M., Sperling, L.J., Schwieters, C.D., Nesbitt, A.E., Gennis, R.B., Rienstra, C.M. | NOT | SOLID-STATE NMR | null | null | false | false | IGHV5 | IGKV8 | Kappa | null | null | null | null | null |
5y9c | H | L | 0 | D | A | C | E | protein | protein | protein | protein | NA | NA | NA | NA | major capsid protein l1 | major capsid protein l1 | major capsid protein l1 | major capsid protein l1 | STRUCTURAL PROTEIN/IMMUNE SYSTEM | 08/24/17 | Crystal structure of HPV58 pentamer in complex with the Fab fragment of antibody A12A3 | HUMAN PAPILLOMAVIRUS TYPE 58; MUS MUSCULUS | mus musculus | mus musculus | human papillomavirus type 58 | human papillomavirus type 58 | human papillomavirus type 58 | human papillomavirus type 58 | Li, S.W., Li, Z.H. | 3.443 | X-RAY DIFFRACTION | 0.249 | 0.202 | false | false | IGHV14 | IGKV19 | Kappa | null | null | null | null | null |
6snc | B | A | 0 | C | peptide | null | envelope glycoprotein gp160 | IMMUNE SYSTEM | 08/23/19 | crystal structure of LN01 Fab in complex with an HIV-1 gp41 peptide | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Caillat, C., Pinto, D., Corti, D., Fenwick, C., Pantaleo, G., Weissenhorn, W. | 3.2 | X-RAY DIFFRACTION | 0.254 | 0.213 | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
4xnz | H | L | 0 | G | protein | null | envelope glycoprotein gp160,envelope glycoprotein gp160 | IMMUNE SYSTEM | 01/16/15 | Crystal structure of broadly and potently neutralizing antibody VRC06B in complex with HIV-1 clade A/E strain 93TH057 gp120 | HOMO SAPIENS; HUMAN IMMUNODEFICIENCY VIRUS 1 | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Zhou, T., Srivatsan, S., Kwong, P.D. | 3.389 | X-RAY DIFFRACTION | 0.301 | 0.244 | false | true | unknown | unknown | unknown | null | null | null | null | null |
3tv3 | H | L | 0 | A | carbohydrate | MAN | ALPHA-D-MANNOSE | IMMUNE SYSTEM | 09/19/11 | Crystal structure of broad and potent HIV-1 neutralizing antibody PGT128 in complex with Man9 | HOMO SAPIENS | homo sapiens | homo sapiens | null | Pejchal, R., Wilson, I.A. | 1.29 | X-RAY DIFFRACTION | 0.184 | 0.159 | false | true | IGHV4 | IGLV2 | Lambda | null | null | null | null | null |
6nms | H | L | 0 | S | protein | null | tyrosine-protein phosphatase non-receptor type substrate 1 | IMMUNE SYSTEM | 01/11/19 | Blocking Fab 136 anti-SIRP-alpha antibody in complex with SIRP-alpha Variant 1 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Wibowo, A.S., Carter, J.J., Sim, J. | 2.11 | X-RAY DIFFRACTION | 0.244 | 0.204 | false | true | IGHV3 | IGKV3 | Kappa | null | null | null | null | null |
7sfx | J | K | 0 | null | null | null | null | IMMUNE SYSTEM | 10/04/21 | 10A1 Fab in complex with CD99 peptide | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | null | Romero, L.A., Hattori, T., Koide, S. | 3.1 | X-RAY DIFFRACTION | 0.248 | 0.226 | false | true | IGHV6 | IGLV3 | Lambda | null | null | null | null | null |
5d9q | D | d | 0 | G | protein | null | envelope glycoprotein gp120 | IMMUNE SYSTEM | 08/18/15 | Crystal Structure of the BG505 SOSIP gp140 HIV-1 Env trimer in Complex with the Broadly Neutralizing Fab PGT122 and scFv NIH45-46 | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | null | human immunodeficiency virus 1 | Julien, J.-P., Stanfield, R.L., Ward, A.B., Wilson, I.A. | 4.4 | X-RAY DIFFRACTION | 0.320 | 0.290 | true | true | unknown | unknown | unknown | null | null | null | null | null |
4evn | K | L | 0 | null | null | null | null | immune system | 04/26/12 | Crystal Structure of Fab CR6261 (somatic heavy chain with germline-reverted light chain) | HOMO SAPIENS | homo sapiens | homo sapiens | null | Whittle, J.R.R. | 2.851 | X-RAY DIFFRACTION | 0.293 | 0.230 | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
7l06 | H | L | 0 | U | carbohydrate | MAN | ALPHA-D-MANNOSE | VIRAL PROTEIN/IMMUNE SYSTEM | 12/11/20 | Cryo-EM structure of SARS-CoV-2 2P S ectodomain bound to two copies of domain-swapped antibody 2G12 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | homo sapiens | homo sapiens | null | Manne, K., Henderson, R., Acharya, P. | 3.3 | ELECTRON MICROSCOPY | null | null | false | true | unknown | IGKV1 | Kappa | null | null | null | null | null |
7p6k | G | null | 0 | B | protein | null | volume-regulated anion channel subunit lrrc8a | MEMBRANE PROTEIN | 07/16/21 | Structure of homomeric LRRC8A Volume-Regulated Anion Channel in complex with synthetic nanobody Sb5 | MUS MUSCULUS; SYNTHETIC CONSTRUCT | synthetic construct | null | mus musculus | Deneka, D., Rutz, S., Sawicka, M. | 3.8 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
6x3v | J | I | 0 | B | protein | null | gamma-aminobutyric acid receptor subunit alpha-1 | MEMBRANE PROTEIN | 05/21/20 | Human GABAA receptor alpha1-beta2-gamma2 subtype in complex with GABA plus etomidate | HOMO SAPIENS; MUS MUSCULUS | mus musculus | mus musculus | homo sapiens | Kim, J.J., Gharpure, A., Teng, J., Zhuang, Y., Howard, R.J., Zhu, S., Noviello, C.M., Walsh, R.M., Lindahl, E., Hibbs, R.E. | 3.5 | ELECTRON MICROSCOPY | null | null | false | false | IGHV14 | IGKV6 | Kappa | null | null | null | null | null |
5vl3 | H | L | 0 | Q | protein | null | b-cell receptor cd22 | IMMUNE SYSTEM | 04/24/17 | CD22 d1-d3 in complex with therapeutic Fab Epratuzumab | HOMO SAPIENS; MUS MUSCULUS | mus musculus, homo sapiens | mus musculus, homo sapiens | homo sapiens | Sicard, T., Ereno-Orbea, J., Julien, J.P. | 3.1 | X-RAY DIFFRACTION | 0.295 | 0.280 | false | true | IGHV1 | IGKV8 | Kappa | null | null | null | null | null |
5i5k | X | Y | 0 | A | protein | null | complement c5 | IMMUNE SYSTEM | 02/15/16 | Structure of complement C5 in complex with eculizumab | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Schatz-Jakobsen, J.A., Andersen, G.R. | 4.2 | X-RAY DIFFRACTION | 0.244 | 0.205 | false | true | IGHV1 | IGKV1 | Kappa | 0 | -14.671746 | SPR | null | TBD |
3u79 | null | A | 0 | null | null | null | null | IMMUNE SYSTEM | 10/13/11 | AL-103 Y32F Y96F | HOMO SAPIENS | null | homo sapiens | null | DiCostanzo, A.C., Thompson, J.R., Ramirez-Alvarado, M. | 1.62 | X-RAY DIFFRACTION | 0.223 | 0.169 | false | true | null | IGKV1 | Kappa | null | null | null | null | null |
7lvu | D | null | 0 | null | null | null | null | IMMUNE SYSTEM | 02/26/21 | Structure of RSV F-directed VHH Cl184 | LAMA GLAMA | lama glama | null | null | Hsieh, C.-L., McLellan, J.S. | 1.94 | X-RAY DIFFRACTION | 0.233 | 0.208 | false | true | IGHV1 | null | null | null | null | null | null | null |
7rdm | B | A | 0 | C | carbohydrate | NAG | N-ACETYL-D-GLUCOSAMINE | IMMUNE SYSTEM | 07/09/21 | Crystal structure of PCDN-38B, a broadly neutralizing anti-HIV antibody | HOMO SAPIENS | homo sapiens | homo sapiens | null | Omorodion, O., Wilson, I.A. | 2.08 | X-RAY DIFFRACTION | 0.219 | 0.191 | false | true | IGHV4 | IGKV3 | Kappa | null | null | null | null | null |
7mlu | N | O | 0 | D | protein | null | glycine receptor alpha 1 | MEMBRANE PROTEIN, SIGNALING PROTEIN | 04/29/21 | Cryo-EM reveals partially and fully assembled native glycine receptors,homomeric pentamer | RATTUS NORVEGICUS; SUS SCROFA | rattus norvegicus | rattus norvegicus | sus scrofa | Zhu, H., Gouaux, E. | 4.1 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | IGKV6 | Kappa | null | null | null | null | null |
7s8g | H | L | 0 | null | null | null | null | ANTIVIRAL PROTEIN,IMMUNE SYSTEM | 09/17/21 | Structure of anti-LASV Fab 25.10C with FNQI mutation | HOMO SAPIENS | homo sapiens | homo sapiens | null | Hastie, K.M., Enriquez, A.S. | 2.57 | X-RAY DIFFRACTION | 0.263 | 0.220 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
7n9c | E | null | 0 | A | protein | null | spike glycoprotein | VIRAL PROTEIN/IMMUNE SYSTEM | 06/17/21 | Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting novel and conserved epitopes-CovS with NB95 | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; LAMA GLAMA | lama glama | null | severe acute respiratory syndrome coronavirus2 | Sun, D., Zhang, C., Shi, Y. | 3.71 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
2nyy | D | C | 0 | A | protein | null | botulinum neurotoxin type a | TOXIN/IMMUNE SYSTEM | 11/21/06 | Crystal structure of botulinum neurotoxin type A complexed with monoclonal antibody CR1 | HOMO SAPIENS; CLOSTRIDIUM BOTULINUM | null | null | clostridium botulinum | Stevens, R.C., Arndt, J.W. | 2.61 | X-RAY DIFFRACTION | 0.246 | 0.206 | false | false | IGHV5 | IGKV3 | Kappa | 0 | -15.72 | Other | 23 | 17173035 |
6dca | J | N | 0 | R | peptide | null | microtubule-associated protein tau | IMMUNE SYSTEM | 05/04/18 | Fab/epitope complex of mouse monoclonal antibody 6B2 targeting a non-phosphorylated tau epitope. | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | homo sapiens | Chukwu, J.E., Kong, X.-P. | 2.599 | X-RAY DIFFRACTION | 0.259 | 0.189 | false | false | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
7dk4 | a | b | 0 | A | protein | null | spike glycoprotein | VIRAL PROTEIN | 11/23/20 | S-2H2-F3a structure, two RBDs are up and one RBD is down, each RBD binds with a 2H2 Fab. | SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; MUS MUSCULUS | mus musculus | mus musculus | severe acute respiratory syndrome coronavirus2 | Cong, Y., Wang, Y.F. | 3.8 | ELECTRON MICROSCOPY | null | null | false | false | IGHV2 | IGKV3 | Kappa | null | null | null | null | null |
5cus | K | O | 0 | D | protein | null | receptor tyrosine-protein kinase erbb-3 | TRANSFERASE | 07/25/15 | Crystal Structure of sErbB3-Fab3379 Complex | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Lee, S., Schlessinger, J. | 3.2 | X-RAY DIFFRACTION | 0.278 | 0.252 | false | true | IGHV3 | IGLV1 | Lambda | null | null | null | null | null |
6m2r | H | L | 0 | A | protein | null | sodium-dependent dopamine transporter | MEMBRANE PROTEIN | 02/28/20 | X-ray structure of a functional Drosophila dopamine transporter in L-norepinephrine bound form | DROSOPHILA MELANOGASTER; MUS MUSCULUS | mus musculus | mus musculus | drosophila melanogaster | Shabareesh, P., Mallela, A.K., Joseph, D., Penmatsa, A. | 2.802 | X-RAY DIFFRACTION | 0.247 | 0.211 | false | true | IGHV5 | IGKV4 | Kappa | null | null | null | null | null |
7nik | F | null | 0 | A | B | protein | protein | NA | NA | polymerase acidic protein | rna-directed rna polymerase catalytic subunit | VIRAL PROTEIN | 02/12/21 | 1918 H1N1 Viral influenza polymerase heterotrimer with Nb8189 core | INFLUENZA A VIRUS (STRAIN A/BREVIG MISSION/1/1918 H1N1); STAPHYLOCOCCUS AUREUS; CAMELIDAE MIXED LIBRARY; SYNTHETIC CONSTRUCT | camelidae mixed library | null | influenza a virus (strain a/brevigmission/1/1918 h1n1) | influenza a virus (strain a/brevigmission/1/1918 h1n1) | Keown, J.R., Carrique, L., Fodor, E., Grimes, J.M. | 6.2 | ELECTRON MICROSCOPY | null | null | false | true | IGHV1 | null | null | null | null | null | null | null |
3auv | F | f | 0 | null | null | null | null | IMMUNE SYSTEM | 02/16/11 | Predicting Amino Acid Preferences in the Complementarity Determining Regions of an Antibody-Antigen Recognition Interface | HOMO SAPIENS | homo sapiens | null | null | Yu, C.M., Peng, H.P., Chen, I.C., Lee, Y.C., Chen, J.B., Tsai, K.C., Chen, C.T., Chang, J.Y., Yang, E.W., Hsu, P.C., Jian, J.W., Hsu, H.J., Chang, H.J., Hsu, W.L., Huang, K.F., Ma, A.C., Yang, A.S. | 2.4 | X-RAY DIFFRACTION | 0.251 | 0.216 | true | true | unknown | unknown | unknown | null | null | null | null | null |
7r23 | C | null | 0 | A | protein | null | arc | STRUCTURAL PROTEIN | 02/04/22 | Crystal structure of human Arc CTD in complex with two anti-Arc nanobodies | HOMO SAPIENS; VICUGNA PACOS | vicugna pacos | null | homo sapiens | Markusson, S., Kursula, P. | 2.77 | X-RAY DIFFRACTION | 0.302 | 0.252 | false | true | IGHV1 | null | null | null | null | null | null | null |
3eo1 | H | G | 0 | I | protein | null | transforming growth factor beta-3 | IMMUNE SYSTEM/CYTOKINE | 09/26/08 | Structure of the Fab Fragment of GC-1008 in Complex with Transforming Growth Factor-Beta 3 | MUS MUSCULUS; HOMO SAPIENS | mus musculus | mus musculus | homo sapiens | Gruetter, C., Gruetter, M.G. | 3.1 | X-RAY DIFFRACTION | 0.279 | 0.255 | false | true | IGHV1 | IGKV8 | Kappa | 0 | -13.09 | Other | null | 19073914 |
7pnm | I | E | 0 | C | protein | null | spike glycoprotein | VIRAL PROTEIN | 09/07/21 | Human coronavirus OC43 spike glycoprotein ectodomain in complex with the 46C12 antibody Fab fragment | HUMAN CORONAVIRUS OC43; HOMO SAPIENS | homo sapiens | homo sapiens | human coronavirus oc43 | Hurdiss, D.L. | 3.7 | ELECTRON MICROSCOPY | null | null | false | true | IGHV3 | IGKV2 | Kappa | null | null | null | null | null |
1rzk | H | L | 0 | G | protein | null | envelope glycoprotein gp120 | Viral protein/Immune system | 12/24/03 | HIV-1 YU2 GP120 ENVELOPE GLYCOPROTEIN COMPLEXED WITH CD4 AND INDUCED NEUTRALIZING ANTIBODY 17B | HUMAN IMMUNODEFICIENCY VIRUS 1; HOMO SAPIENS | homo sapiens | homo sapiens | human immunodeficiency virus 1 | Huang, C.C., Venturi, M., Majeed, S., Moore, M.J., Phogat, S., Zhang, M.-Y., Dimitrov, D.S., Hendrickson, W.A., Robinson, J., Sodroski, J., Wyatt, R., Choe, H., Farzan, M., Kwong, P.D. | 2.9 | X-RAY DIFFRACTION | 0.297 | 0.205 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
7zfb | M | null | 0 | E | protein | null | spike protein s1 | VIRAL PROTEIN | 04/01/22 | SARS-CoV-2 Omicron RBD in complex with nanobody C1, Omi-18 and Omi-31 Fabs | LAMA GLAMA; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2; HOMO SAPIENS | lama glama | null | severe acute respiratory syndrome coronavirus2 | Zhou, D., Huo, J., Ren, J., Stuart, D.I. | 3.08 | X-RAY DIFFRACTION | 0.308 | 0.261 | false | true | IGHV1 | null | null | null | null | null | null | null |
7shy | C | D | 0 | A | protein | null | ige fc | IMMUNE SYSTEM | 10/11/21 | IgE-Fc in complex with omalizumab scFv | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Pennington, L.F., Jardetzky, T.J., Kleinboelting, S. | 3.0 | X-RAY DIFFRACTION | 0.230 | 0.173 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
3ujt | H | L | 0 | null | null | null | null | IMMUNE SYSTEM | 11/08/11 | Structure of the Fab fragment of Ab-52, an antibody that binds the O-antigen of Francisella tularensis | MUS MUSCULUS | mus musculus | mus musculus | null | Rynkiewicz, M.J., Lu, Z., Hui, J.H., Sharon, J., Seaton, B.A. | 2.1 | X-RAY DIFFRACTION | 0.220 | 0.186 | false | false | IGHV1 | IGKV8 | Kappa | null | null | null | null | null |
7dk0 | A | B | 0 | C | protein | null | spike protein s1 | IMMUNE SYSTEM/VIRAL PROTEIN | 11/22/20 | Crystal structure of SARS-CoV-2 Spike RBD in complex with MW05 Fab | HOMO SAPIENS; SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 | homo sapiens | homo sapiens | severe acute respiratory syndrome coronavirus2 | Wang, J., Jiao, S., Wang, R., Zhang, J., Zhang, M., Wang, M. | 3.199 | X-RAY DIFFRACTION | 0.265 | 0.218 | false | true | IGHV1 | IGKV3 | Kappa | null | null | null | null | null |
15c8 | H | L | 0 | null | null | null | null | CATALYTIC ANTIBODY | 03/18/98 | CATALYTIC ANTIBODY 5C8, FREE FAB | MUS MUSCULUS | mus musculus | mus musculus | null | Gruber, K., Wilson, I.A. | 2.5 | X-RAY DIFFRACTION | 0.251 | 0.190 | false | false | IGHV14 | IGKV4 | Kappa | null | null | null | null | null |
7amq | H | L | 0 | B | protein | null | human a6 t-cell receptor beta chain trbc1 | IMMUNE SYSTEM | 10/09/20 | Crystal structure of the complex of HuJovi-1 Fab with the human TRBC2 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Ferrari, M., Bulek, A., Bughda, R., Jha, R., Welin, M., Logan, D.T., Sewell, A., Onuoha, S., Pule, M. | 2.353 | X-RAY DIFFRACTION | 0.249 | 0.201 | false | true | IGHV1 | IGKV1 | Kappa | null | null | null | null | null |
5boz | I | null | 0 | C | protein | null | ricin | Hydrolase/Immune system | 05/27/15 | Ricin A chain bound to camelid nanobody (VHH9)(E1) | RICINUS COMMUNIS; LAMA GLAMA | lama glama | null | ricinus communis | Rudolph, M.J., Mantis, N. | 3.1 | X-RAY DIFFRACTION | 0.277 | 0.215 | false | true | IGHV1 | null | null | 0 | -12.489521 | SPR | null | TBD |
6heq | A | null | 0 | null | null | null | null | PROTEIN BINDING | 08/20/18 | Prion nanobody 484 | CAMELUS DROMEDARIUS | camelus dromedarius | null | null | Soror, S.H., Abskharon, R.N., Wohlkonig, A. | 1.23 | X-RAY DIFFRACTION | 0.224 | 0.199 | false | true | IGHV3 | null | null | null | null | null | null | null |
3jcc | C | B | 0 | A | protein | null | envelope glycoprotein gp120 | VIRAL PROTEIN/IMMUNE SYSTEM | 11/25/15 | Structure of Simian Immunodeficiency Virus Envelope Spikes bound with CD4 and Monoclonal Antibody 36D5 | HOMO SAPIENS; SIMIAN IMMUNODEFICIENCY VIRUS | homo sapiens | homo sapiens | simian immunodeficiency virus | Hu, G., Liu, J., Roux, K., Taylor, K.A. | NOT | ELECTRON MICROSCOPY | null | null | false | false | IGHV4 | IGLV3 | Lambda | null | null | null | null | null |
1oax | J | N | 0 | J | Hapten | ANQ | ACENAPHTHENEQUINONE | IMMUNE SYSTEM | 01/21/03 | Fv Structure of the IgE SPE-7 in complex with acenaphthenequinone | RATTUS RATTUS | rattus rattus | rattus rattus | rattus rattus | James, L.C., Roversi, P., Tawfik, D. | 2.67 | X-RAY DIFFRACTION | 0.282 | 0.238 | false | true | IGHV1 | IGLV1 | Lambda | null | null | null | null | null |
6z3q | H | L | 0 | C | A | B | protein | protein | protein | NA | NA | NA | vp3 | vp1 | vp2 | VIRUS | 05/21/20 | Structure of EV71 in complex with a protective antibody 38-1-10A Fab | HOMO SAPIENS; ENTEROVIRUS A71 | homo sapiens | homo sapiens | enterovirus a71 | enterovirus a71 | enterovirus a71 | Zhou, D., Fry, E.E., Ren, J., Stuart, D.I. | 2.7 | ELECTRON MICROSCOPY | null | null | false | true | IGHV4 | IGKV1 | Kappa | null | null | null | null | null |
6pe9 | H | L | 0 | V | protein | null | tumor necrosis factor receptor superfamily member 5 | IMMUNE SYSTEM | 06/20/19 | Crystal Structure of CD40 complexed to FAB516 | HOMO SAPIENS | homo sapiens | homo sapiens | homo sapiens | Argiriadi, M.A. | 3.13 | X-RAY DIFFRACTION | 0.255 | 0.216 | false | true | IGHV3 | IGKV4 | Kappa | null | null | null | null | null |
7pi3 | W | X | 0 | V | protein | null | cysteine-rich protective antigen | IMMUNE SYSTEM | 08/19/21 | PfCyRPA bound to Fab fragments from monoclonal antibodies Cy.003, Cy.004 and Cy.007 | PLASMODIUM FALCIPARUM 3D7; GALLUS GALLUS | gallus gallus | gallus gallus | plasmodium falciparum 3d7 | Ragotte, R.J., Higgins, M.K. | 3.269 | X-RAY DIFFRACTION | 0.298 | 0.285 | false | true | unknown | unknown | unknown | null | null | null | null | null |
5m30 | D | null | 0 | B | protein | null | type vi secretion protein | SECRETION SYSTEM | 10/13/16 | Structure of TssK from T6SS EAEC in complex with nanobody nb18 | VICUGNA PACOS; ESCHERICHIA COLI | vicugna pacos | null | escherichia coli | Nguyen, V.S., Cambillau, C., Spinelli, C., Desmyter, A., Legrand, P., Cascales, E. | 2.6 | X-RAY DIFFRACTION | 0.226 | 0.207 | false | true | IGHV1 | null | null | null | null | null | null | null |
6bb4 | I | M | 0 | Q | peptide | null | microtubule-associated protein tau | IMMUNE SYSTEM | 10/16/17 | Fab/epitope complex of mouse monoclonal antibody C5.2 targeting a phospho-tau epitope. | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | homo sapiens | Chukwu, J.E., Kong, X.-P. | 2.099 | X-RAY DIFFRACTION | 0.270 | 0.218 | false | false | IGHV1 | IGKV11 | Kappa | 0 | -10.658129 | Unknown | null | TBD |
7c94 | B | A | 0 | C | peptide | null | peptide from podoplanin | IMMUNE SYSTEM | 06/04/20 | Crystal structure of the anti-human podoplanin antibody Fab fragment complex with glycopeptide | MUS MUSCULUS; SYNTHETIC CONSTRUCT | mus musculus | mus musculus | homo sapiens | Suzuki, K., Nakamura, S., Ogasawara, S., Naruchi, K., Shimabukuro, J., Tukahara, N., Kaneko, M.K., Kato, Y., Murata, T. | 2.84 | X-RAY DIFFRACTION | 0.255 | 0.220 | false | false | IGHV5 | IGKV8 | Kappa | null | null | null | null | null |
4ij3 | C | B | 0 | A | protein | null | sulfhydryl oxidase 1 | OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR | 12/21/12 | Oxidoreductase Fragment of Human QSOX1 in Complex with a FAB Fragment from an Anti- Human QSOX1 Antibody | MUS MUSCULUS; HOMO SAPIENS | mus musculus | mus musculus | homo sapiens | Fass, D., Grossman, I. | 2.7 | X-RAY DIFFRACTION | 0.237 | 0.202 | false | true | IGHV2 | IGKV6 | Kappa | null | null | null | null | null |
6xjz | H | L | 0 | A | nucleic-acid | null | self-alkylating ribozyme (58-mer) | RNA/IMMUNE SYSTEM | 06/24/20 | Crystal structure of a self-alkylating ribozyme - apo form | HOMO SAPIENS; SYNTHETIC CONSTRUCT | homo sapiens | homo sapiens | aeropyrum pernix | Koirala, D., Piccirilli, J.A. | 2.488 | X-RAY DIFFRACTION | 0.264 | 0.200 | false | true | IGHV3 | IGKV1 | Kappa | null | null | null | null | null |
6uc6 | C | null | 0 | A | protein | null | botulinum neurotoxin type b | HYDROLASE/ANTITOXIN | 09/15/19 | Crystal structure of BoNT/B receptor-binding domain in complex with VHH JLI-H11 | CLOSTRIDIUM BOTULINUM; VICUGNA PACOS | vicugna pacos | null | clostridium botulinum | Lam, K., Jin, R. | 2.32006 | X-RAY DIFFRACTION | 0.222 | 0.170 | false | true | IGHV1 | null | null | null | null | null | null | null |
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