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10.1007/s12268-019-1003-4
The customized proteome: Protein modification by proteolysis
Site-specific proteolytic processing is an irreversible post-translational protein modification with essential regulatory functions. Dedicated methods enable proteome-wide characterization of differentially processed proteoforms based on their distinct protease-generated N termini. Exemplary profiling of murine glomeru...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Integrative Biology: from Genes and Genomes to Systems", "Physiology in Health, Disease and Ageing" ]
10.1364/CLEO_QELS.2013.QM1D.4
All Optical Polariton Transistor
Optical technology has proved to be the best choice for the transmission of information at high data rate over long distances. However, the implementation of high-speed, low-energy, all-optical logics in semiconductors represents a formidable challenge due to the intrinsic difficulty of all-optical devices to satisfy t...
[ "Condensed Matter Physics", "Systems and Communication Engineering" ]
10.1088/1748-9326/10/10/104012
The Dependence Of Wintertime Mediterranean Precipitation On The Atmospheric Circulation Response To Climate Change
Climate models indicate a future wintertime precipitation reduction in the Mediterranean region but there is large uncertainty in the amplitude of the projected change. We analyse CMIP5 climate model output to quantify the role of atmospheric circulation in the Mediterranean precipitation change. It is found that a sim...
[ "Earth System Science" ]
10.1029/2018GL077427
Characterization of the Extraterrestrial Magnesium Source in the Atmosphere Using a Meteoric Ablation Simulator
Ablation of Mg from meteoroids entering the Earth's atmosphere was studied experimentally using a Meteoric Ablation Simulator: micron-sized particles of representative meteoritic material were flash heated to simulate atmospheric entry and the ablation rate of Mg with respect to Na measured by fast time-resolved laser-...
[ "Physical and Analytical Chemical Sciences", "Universe Sciences" ]
10.1021/jacs.8b05332
Major G-Quadruplex Form of HIV-1 LTR Reveals a (3 + 1) Folding Topology Containing a Stem-Loop
Nucleic acids can form noncanonical four-stranded structures called G-quadruplexes. G-quadruplex-forming sequences are found in several genomes including human and viruses. Previous studies showed that the G-rich sequence located in the U3 promoter region of the HIV-1 long terminal repeat (LTR) folds into a set of dyna...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Immunity, Infection and Immunotherapy", "Prevention, Diagnosis and Treatment of Human Diseases" ]
US 2008/0075118 W
SUBSTITUTED AMINO ALCOHOLS
Disclosed herein are substituted amino alcohol anti-mycobacterial agents and/or chelation therapy agents of Formula (I), process of preparation thereof, pharmaceutical compositions thereof, and methods of use thereof.
[ "Synthetic Chemistry and Materials", "Prevention, Diagnosis and Treatment of Human Diseases" ]
W2148991756
An Action–Sound Approach to Teaching Interactive Music
The conceptual starting point for an ‘action–sound approach’ to teaching music technology is the acknowledgment of the couplings that exist in acoustic instruments between sounding objects, sound-producing actions and the resultant sounds themselves. Digital music technologies, on the other hand, are not limited to suc...
[ "Systems and Communication Engineering", "Computer Science and Informatics" ]
W1941445231
Stoichiometry control of the electronic properties of the LaAlO3/SrTiO3 heterointerface
We investigate the effect of the laser parameters of pulsed laser deposition on the film stoichiometry and electronic properties of LaAlO_3/SrTiO_3 (001) heterostructures. The La/Al ratio in the LaAlO_3 films was varied over a wide range from 0.88 to 1.15, and was found to have a strong effect on the interface conducti...
[ "Condensed Matter Physics", "Materials Engineering" ]
10.1016/j.amepre.2018.02.010
The Impact of U.S. Free Trade Agreements on Calorie Availability and Obesity: A Natural Experiment in Canada
Introduction: Globalization via free trade and investment agreements is often implicated in the obesity pandemic. Concerns center on how free trade and investment agreements increase population exposure to unhealthy, high-calorie diets, but existing studies preclude causal conclusions. Few studies of free trade and inv...
[ "Individuals, Markets and Organisations", "Prevention, Diagnosis and Treatment of Human Diseases" ]
10.1371/journal.pone.0158558
Regional regulation of purkinje cell dendritic spines by integrins and Eph/ephrins
Climbing fibres and parallel fibres compete for dendritic space on Purkinje cells in the cerebellum. Normally, climbing fibres populate the proximal dendrites, where they suppress the multiple small spines typical of parallel fibres, leading to their replacement by the few large spines that contact climbing fibres. Pre...
[ "Neuroscience and Disorders of the Nervous System", "Cell Biology, Development, Stem Cells and Regeneration" ]
interreg_2082
Landscape opportunities for territorial organization
As emphasised by the ESDP and the European Landscape Convention, the different landscape characterization of the territories is a resource to safeguard. Given that the territory is constantly developing, transformations of the landscape cannot be avoided, but it is important for them to be guided with awareness. On the...
[ "Human Mobility, Environment, and Space", "Earth System Science" ]
W2140708727
Who were the urban gentry? Social elites in an English provincial town, c. 1680–1760
ABSTRACT This paper explores the identity and social worlds of the ‘urban gentry’ of Chester as they developed from the late seventeenth to the mid eighteenth century. In place of the political and cultural definitions which characterise analyses of this group, it takes the self-defined ‘occupational’ titles of probate...
[ "The Study of the Human Past", "The Social World and Its Interactions" ]
10.1021/jp200399p
Structural and electronic properties of helical TiS<inf>2</inf> nanotubes studied with objective molecular dynamics
Structural and electronic properties of chiral and achiral single-walled TiS2 nanotubes are the focus of the present paper. Two TiS 2 nanotube structures (with octahedrally and trigonal-prismatically coordinated walls) have been systematically investigated by means of an objective molecular dynamics method coupled with...
[ "Condensed Matter Physics", "Synthetic Chemistry and Materials" ]
10.1002/pssr.201900381
Imaging Nanoscale Inhomogeneities and Edge Delamination in As-Grown MoS<inf>2</inf> Using Tip-Enhanced Photoluminescence
Methods for nanoscale material characterization are in ever-increasing demand, especially those that can provide a broader range of information at once. Near-field techniques based on combinations of scanning probe microscopy (SPM) and Raman or photoluminescence (PL) spectroscopy (tip-enhanced Raman spectroscopy [TERS]...
[ "Condensed Matter Physics", "Physical and Analytical Chemical Sciences", "Materials Engineering" ]
10.1016/j.cortex.2018.08.019
Adolescents with autism show typical fMRI repetition suppression, but atypical surprise response
Recent theoretical frameworks have hypothesized that autism spectrum disorder (ASD) may be marked by an altered balance between sensory inputs and prior knowledge–the so-called hypoprior hypothesis. Yet evidence regarding such an altered balance is mixed. Here, we aimed to test this hypothesis within the domain of visu...
[ "Neuroscience and Disorders of the Nervous System", "The Human Mind and Its Complexity" ]
10.1073/pnas.1524888113
Indonesian fire activity and smoke pollution in 2015 show persistent nonlinear sensitivity to El Niño-induced drought
The 2015 fire season and related smoke pollution in Indonesia was more severe than the major 2006 episode, making it the most severe season observed by the NASA Earth Observing System satellites that go back to the early 2000s, namely active fire detections from the Terra and Aqua Moderate Resolution Imaging Spectrorad...
[ "Earth System Science", "Environmental Biology, Ecology and Evolution" ]
10.1051/0004-6361/201935941
The Young Stellar Content Of The Giant H Ii Regions M 8 G333 6 0 2 And Ngc 6357 With Vlt Kmos
Context. The identification and characterisation of populations of young massive stars in (giant) HII regions provides important constraints on (i) the formation process of massive stars and their . . .
[ "Universe Sciences" ]
10.1007/s10797-012-9225-0
Bottlenecks in ramping up public investment
A windfall in a developing economy with capital scarcity and investment adjustment costs facing a temporary windfall should be used to give more consumption to poorer present generations and to speed up development by ramping up public investment and paying off debt taking due account of the increasing inefficiency as ...
[ "Individuals, Markets and Organisations" ]
IT 0300140 W
METHOD FOR THE CREATION OF CLEARANCE HOLES
According to this invention, slots are made on the plane of any material; the depth of these slots is equal to half the thickness of the plane, plus the length of the radius of the stay bolt or stud to be entered, plus a tolerance margin; the slots have the required length and are made on two or more sides of the plane...
[ "Products and Processes Engineering", "Materials Engineering" ]
10.1038/ncomms16032
Activity dependent feedback inhibition may maintain head direction signals in mouse presubiculum
Orientation in space is represented in specialized brain circuits. Persistent head direction signals are transmitted from anterior thalamus to the presubiculum, but the identity of the presubicular target neurons, their connectivity and function in local microcircuits are unknown. Here, we examine how thalamic afferent...
[ "Neuroscience and Disorders of the Nervous System" ]
10.1038/s41598-018-36087-8
Figure-ground perception in the awake mouse and neuronal activity elicited by figure-ground stimuli in primary visual cortex
Figure-ground segregation is the process by which the visual system identifies image elements of figures and segregates them from the background. Previous studies examined figure-ground segregation in the visual cortex of monkeys where figures elicit stronger neuronal responses than backgrounds. It was demonstrated in ...
[ "Neuroscience and Disorders of the Nervous System" ]
US 0120882 W
GREASE, OIL AND WAX RESISTANT PAPER COMPOSITION
In order to provide grease, oil and wax resistance to a paper substrate, a coating containing a binder, a filler material and calcium carbonate is used. The coating of the invention is essentially free from fluorocarbons, which are considered harmful to human and animal populations, and surfactants and other chemicals ...
[ "Materials Engineering", "Synthetic Chemistry and Materials" ]
631906
Neural circuit mechanisms of memory destabilization
Memories can be rendered rewritable through a phenomenon called reconsolidation. The all-limiting step in this memory re-evaluation process is its initiation; the retrieval-dependent destabilization of the memory. However, the understanding of how a stable memory can be switched into a vulnerable but modifiable state i...
[ "Neuroscience and Disorders of the Nervous System", "Integrative Biology: from Genes and Genomes to Systems" ]
10.1515/cog-2014-0089
Vision verbs dominate in conversation across cultures, but the ranking of non-visual verbs varies
AbstractTo what extent does perceptual language reflect universals of experience and cognition, and to what extent is it shaped by particular cultural preoccupations? This paper investigates the universality~relativity of perceptual language by examining the use of basic perception terms in spontaneous conversation acr...
[ "The Human Mind and Its Complexity", "Studies of Cultures and Arts" ]
10.1111/bij.12754
Habitat use and its implications to functional morphology: Niche partitioning and the evolution of locomotory morphology in Lake Tanganyikan cichlids (Perciformes: Cichlidae)
Animal locomotory morphology, i. e. morphological features involved in locomotion, is under the influence of a diverse set of ecological and behavioral factors. In teleost fish, habitat choice and foraging strategy are major determinants of locomotory morphology. In this study, we assess the influence of habitat use a...
[ "Environmental Biology, Ecology and Evolution" ]
10.1088/0067-0049/199/1/15
Bayesian Noise Estimation For Non Ideal Cosmic Microwave Background Experiments
We describe a Bayesian framework for estimating the time-domain noise covariance of cosmic microwave background (CMB) observations, typically parameterized in terms of a 1/f frequency profile. This framework is based on the Gibbs sampling algorithm, which allows for exact marginalization over nuisance parameters throug...
[ "Universe Sciences", "Computer Science and Informatics" ]
283837
Local Governance and Dynamic Conflict in Developing Countries
This proposal is divided into two main strands. The first strand seeks to understand the effects of local marginal institutional change in autocracies. In particular, we will examine the introduction of local democracy in rural China. Our first contribution is to collect a representative panel of villages in rural Chi...
[ "Institutions, Governance and Legal Systems", "Individuals, Markets and Organisations" ]
10.3390/s19061341
Accurate Positioning System Based on Chipless Technology
In this paper, we present an accurate method to localize an object on a 2D plan using the chipless technology. This method requires a single antenna and a chipless tag. Phase difference between a reference position and an unknown position is used to estimate the distances between each resonator and the antenna. Then, m...
[ "Systems and Communication Engineering", "Computer Science and Informatics" ]
10.1063/1.4862930
Thermochromic Undoped And Mg Doped Vo2 Thin Films And Nanoparticles Optical Properties And Performance Limits For Energy Efficient Windows
Undoped and Mg-doped thermochromic VO2 films with atom ratios z equivalent to Mg/(Mg + V) of 0 <= z < 0. 21 were deposited by reactive DC magnetron sputtering onto heated glass and carbon subs . . .
[ "Condensed Matter Physics", "Synthetic Chemistry and Materials", "Materials Engineering" ]
10.1145/2980179.2980221
Birefractive Stereo Imaging For Single Shot Depth Acquisition
We propose a novel birefractive depth acquisition method, which allows for single-shot depth imaging by just placing a birefringent material in front of the lens. While most transmissive materials present a single refractive index per wavelength, birefringent crystals like calcite posses two, resulting in a double refr...
[ "Systems and Communication Engineering", "Computer Science and Informatics" ]
W2028062737
A method for estimating radiation interaction coefficients for tissues from single energy CT
A parametric model for the x-ray linear attenuation coefficient is used to describe the compositional dependence of Hounsfield numbers measured by medical CT scanners. Measurements with materials of known density and composition, that span and evenly sample the compositional range of tissues, are written as linear simu...
[ "Physical and Analytical Chemical Sciences", "Prevention, Diagnosis and Treatment of Human Diseases", "Materials Engineering" ]
10.1021/om300983m
Regioselective electrophilic C-H bond activation in triazolylidene metal complexes containing a N-bound phenyl substituent
Transmetalation of a 1,4-diphenyl-substituted 1,2,3-triazolylidene silver complex with an electrophilic metal center, e. g. , RuII, Ir III, or RhIII, induces spontaneous and chemoselective cyclometalation involving C-H bond activation of the N-bound phenyl group exclusively. Less electrophilic metals such as IrI, RhI, ...
[ "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials" ]
10.1016/j.physbeh.2018.03.021
Allo-parental care in Damaraland mole-rats is female biased and age dependent, though independent of testosterone levels
In Damaraland mole-rats (Fukomys damarensis), non-breeding subordinates contribute to the care of offspring born to the breeding pair in their group by carrying and retrieving young to the nest. In social mole-rats and some cooperative breeders, dominant females show unusually high testosterone levels and it has been s...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Cell Biology, Development, Stem Cells and Regeneration", "Integrative Biology: from Genes and Genomes to Systems" ]
10.1128/AAC.02590-16
Age Weight And Cyp2D6 Genotype Are Major Determinants Of Primaquine Pharmacokinetics In African Children
Low-dose primaquine is recommended to prevent Plasmodium falciparum malaria transmission in areas threatened by artemisinin resistance and areas aiming for malaria elimination. Community treatment campaigns with artemisinin-based combination therapy in combination with the gametocytocidal primaquine dose target all age...
[ "Prevention, Diagnosis and Treatment of Human Diseases", "Immunity, Infection and Immunotherapy", "Physiology in Health, Disease and Ageing" ]
W4284671986
Depois da dialética
PUCCIARELLI, Daniel. Materialismus und Kritik: Konzept, Aussichten und Grenzen des Materialismus um Ausgang von der Negativen Dialektik Theodor W. Adornos. Würzburg: Königshausen &amp; Neumann, 2019.
[ "Texts and Concepts" ]
W1992317257
Experiencing ‘an opening’
As a part of our ongoing exploration of training processes, this article asks a fundamental question that is close to the authors' heart: 'What is Yoga?'. Although this is undoubtedly a question that has no fixed and determined response, it becomes the framing through which we consider how a knowledge and daily practic...
[ "Studies of Cultures and Arts", "The Human Mind and Its Complexity", "Texts and Concepts" ]
10.1080/20548923.2015.1110421
Textile Technology In Nepal In The 5Th 7Th Centuries Ce The Case Of Samdzong
AbstractThe first results of textile and dye analyses of cloth remains recovered in Samdzong, Upper Mustang, Nepal, are presented. The site consists of ten shaft tombs, dated between the 400-650 CE, cut into a high cliff face at an elevation of 4000 m asl. The dry climate and high altitude favoured the exceptional pres...
[ "The Study of the Human Past", "Materials Engineering" ]
10.1007/s00221-017-5006-4
Moving higher and higher: imitators’ movements are sensitive to observed trajectories regardless of action rationality
Humans sometimes perform actions which, at least superficially, appear suboptimal to the goal they are trying to achieve. Despite being able to identify these irrational actions from an early age, humans display a curious tendency to copy them. The current study recorded participants’ movements during an established im...
[ "The Human Mind and Its Complexity", "Neuroscience and Disorders of the Nervous System" ]
10.1353/ajm.2018.0013
Stability of the brascamp-lieb constant and applications
We prove that the best constant in the general Brascamp-Lieb inequality is a locally bounded function of the underlying linear transformations. As applications we deduce certain very general Fourier restriction, Kakeya-type, and nonlinear variants of the Brascamp-Lieb inequality which have arisen recently in harmonic a...
[ "Mathematics" ]
10.1038/s41467-018-06675-3
Modulation of AMPA receptor surface diffusion restores hippocampal plasticity and memory in Huntington’s disease models
Impaired hippocampal synaptic plasticity contributes to cognitive impairment in Huntington’s disease (HD). However, the molecular basis of such synaptic plasticity defects is not fully understood. Combining live-cell nanoparticle tracking and super-resolution imaging, we show that AMPAR surface diffusion, a key player ...
[ "Neuroscience and Disorders of the Nervous System", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Prevention, Diagnosis and Treatment of Human Diseases" ]
W2107479270
Features of the Earth surface deformations in the Kamchatka peninsula and their relation to geoacoustic emission
Abstract. The paper presents the results of investigations of deformation processes in the near-surface sedimentary rocks, which have been carried out in a seismically active region of the Kamchatka peninsula since 2007. The peculiarity of the experiments on registration of geodeformations is the application of a laser...
[ "Condensed Matter Physics", "Earth System Science" ]
10.1163/22941932-00000013
Complementary Imaging Techniques For Charcoal Examination And Identification
Identification of ancient charcoal fragments is a valuable tool in reconstructing past environments and determining natural and anthropogenic disturbances, and for understanding past cultures and societies. Although in Europe such studies are fairly straightforward, utilising charcoal records from the tropics is more c...
[ "Earth System Science", "The Study of the Human Past", "Physical and Analytical Chemical Sciences" ]
10.1038/srep00285
Developmental regulation of CB1-mediated spike-time dependent depression at immature mossy fiber-CA3 synapses
Early in postnatal life, mossy fibres (MF), the axons of granule cells in the dentate gyrus, release GABA which is depolarizing and excitatory. Synaptic currents undergo spike-time dependent long-term depression (STD-LTD) regardless of the temporal order of stimulation (pre versus post and viceversa). Here we show that...
[ "Neuroscience and Disorders of the Nervous System", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1016/j.molcel.2019.02.027
A Role for Chromatin Remodeling in Cohesin Loading onto Chromosomes
Cohesin is a conserved, ring-shaped protein complex that topologically embraces DNA. Its central role in genome organization includes functions in sister chromatid cohesion, DNA repair, and transcriptional regulation. Cohesin loading onto chromosomes requires the Scc2-Scc4 cohesin loader, whose presence on chromatin in...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Cell Biology, Development, Stem Cells and Regeneration" ]
10.3182/20120823-5-NL-3013.00013
Auto Generation Of Implicit Integrators For Embedded Nmpc With Microsecond Sampling Times
Abstract Algorithms for fast real-time Nonlinear Model Predictive Control (NMPC) for mechatronic systems face several challenges. They need to respect tight real-time constraints and need to run on embedded control hardware with limited computing power and memory. A combination of efficient online algorithms and code g...
[ "Systems and Communication Engineering", "Computer Science and Informatics" ]
W2301900601
EFFECTS OF NEPOTISM AND FAMILY CONFLICTS ON THE PERFORMANCE OF
Drawing on the agency theory and stewardship perspective, this article examines the extent to which nepotism and family conflicts affect the performance of family-owned firms in Tanzania. From a sample of 163 family firms and the Structural Equation Model (SEM) results, our article indicates that nepotism and family co...
[ "Individuals, Markets and Organisations", "Institutions, Governance and Legal Systems" ]
10.1021/jp401017u
Molecular mechanisms for adsorption in Cu-BTC metal organic framework
We use molecular simulations to analyze the preferential adsorption sites of molecules that differ in size, shape, and polarizability in Cu-BTC metal organic framework. The cage system of the framework can be exploited to enhance adsorption of small gases. We find that nonpolar molecules adsorb preferentially in the sm...
[ "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials", "Condensed Matter Physics" ]
683099
Why does Clostridium botulinum kill? – In search for botulinum neurotoxin regulators
Bacterial toxins cause devastating diseases in humans and animals, ranging from necrotic enteritis to gas gangrene and tetraplegia. While toxin synthesis probably endows these bacteria with a selective advantage in their natural habitats, toxigenesis is likely to represent a fitness cost. It is thus plausible that mild...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Cell Biology, Development, Stem Cells and Regeneration", "Integrative Biology: from Genes and Genomes to Systems" ]
10.1038/s41467-018-06388-7
Sex and species specific hearing mechanisms in mosquito flagellar ears
Hearing is essential for the courtship of one of the major carriers of human disease, the mosquito. Males locate females through flight-tone recognition and both sexes engage in mid-air acoustic communications, which can take place within swarms containing thousands of individuals. Despite the importance of hearing for...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Integrative Biology: from Genes and Genomes to Systems", "Environmental Biology, Ecology and Evolution" ]
10.1021/acsenergylett.7b01111
Quantifying Total Superoxide, Peroxide, and Carbonaceous Compounds in Metal-O<inf>2</inf> Batteries and the Solid Electrolyte Interphase
Passivation layers on electrode materials are ubiquitous in nonaqueous battery chemistries and strongly govern performance and lifetime. They comprise breakdown products of the electrolyte including carbonate, alkyl carbonates, alkoxides, carboxylates, and polymers. Parasitic chemistry in metal-O2 batteries forms simil...
[ "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials" ]
10.1186/1471-2180-10-191
Establishment Of A Cre Loxp Recombination System For N Terminal Epitope Tagging Of Genes In Tetrahymena
Background Epitope tagging is a powerful strategy to study the function of proteins. Although tools for C-terminal protein tagging in the ciliated protozoan Tetrahymena thermophila have been developed, N-terminal protein tagging in this organism is still technically demanding.
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Integrative Biology: from Genes and Genomes to Systems" ]
W2154749459
The effect of plant population densities on growth, yield and yield components of two spring rapeseed cultivars
Rapeseed (Brassica napus L.) is an important alternate oilseed crop in eastern Anatolia, Turkey. No information on plant density for rapeseed is available in this region. Therefore a&amp;nbsp;study was initiated to investigate the effects of spacings between rows and spacings within rows on the yield and agronomic char...
[ "Earth System Science", "Biotechnology and Biosystems Engineering" ]
10.1002/hpm.2271
Perspective: Lessons from the past
A considered analysis of some factors used in the past 50-70years in medical education, care on a hospital ward, organisation of health services, medical research and the attitudes of media and politics to health services is described. The possible reasons for changes in these areas over time are considered, and recomm...
[ "Prevention, Diagnosis and Treatment of Human Diseases", "The Social World and Its Interactions" ]
10.1007/s10071-020-01426-8
A dung beetle that path integrates without the use of landmarks
Unusual amongst dung beetles,Scarabaeus galenusdigs a burrow that it provisions by making repeated trips to a nearby dung pile. Even more remarkable is that these beetles return home moving backwards, with a pellet of dung between their hind legs. Here, we explore the strategy thatS. galenususes to find its way home. W...
[ "Environmental Biology, Ecology and Evolution", "Integrative Biology: from Genes and Genomes to Systems" ]
1261536
Anal fistula treatment
Signum Surgical Ltd. is a medical device company developing a solution to anal fistula disease. Anal fistulas are a common rectal disease affecting 2 out of every 10,000 people globally. An anal fistula is an artificial tunnel that, in the majority of cases, develops from an infection that begins within a blocked anal ...
[ "Prevention, Diagnosis and Treatment of Human Diseases", "Materials Engineering", "Products and Processes Engineering" ]
10.1145/2858036.2858328
Machine learning of personal gesture variation in music conducting
This note presents a system that learns expressive and idiosyncratic gesture variations for gesture-based interaction. The system is used as an interaction technique in a music conducting scenario where gesture variations drive music articulation. A simple model based on Gaussian Mixture Modeling is used to allow the u...
[ "Computer Science and Informatics", "Systems and Communication Engineering" ]
W1991442891
‘Shut up and squat!’ Learning body knowledge within the gym
The aim of this article is to describe and analyse learning processes among bodybuilders in bodybuilding environments, focusing on the ways activities form the basis for incorporation of both physical and cultural knowledge. Emanating from an ethnographic study, the arguments are based on a constructionist approach to ...
[ "The Social World and Its Interactions", "The Human Mind and Its Complexity", "Physiology in Health, Disease and Ageing" ]
W2034717186
Supply chain risk management: a literature review
Risk management plays a vital role in effectively operating supply chains in the presence of a variety of uncertainties. Over the years, many researchers have focused on supply chain risk management (SCRM) by contributing in the areas of defining, operationalising and mitigating risks. In this paper, we review and synt...
[ "Individuals, Markets and Organisations" ]
10.1371/journal.pone.0053030
Influence of Pentraxin 3 (PTX3) Genetic Variants on Myocardial Infarction Risk and PTX3 Plasma Levels
PTX3 is a long pentraxin of the innate immune system produced by different cell types (mononuclear phagocytes, dendritic cells, fibroblasts and endothelial cells) at the inflammatory site. It appears to have a cardiovascular protective function by acting on the immune-inflammatory balance in the cardiovascular system. ...
[ "Immunity, Infection and Immunotherapy", "Physiology in Health, Disease and Ageing", "Prevention, Diagnosis and Treatment of Human Diseases" ]
W1082334881
Experimental and numerical investigations on roof slab of a pool type sodium cooled fast reactor based on model studies
Abstract The objective of the work is to predict the structural integrity of the roof slab of 500 MWe sodium cooled fast reactor (SFR) under static loading conditions. The roof slab is an annular box type structure consisting of top and bottom plates with connecting stiffeners and has been designed to support various c...
[ "Products and Processes Engineering", "Materials Engineering" ]
W1981842598
Enantioselective synthesis of the sex pheromone of the grey pineapple mealybug, Dysmicoccus neobrevipes (Hemiptera: Pseudococcidae), for determination of the absolute configuration
The grey pineapple mealybug, Dysmicoccus neobrevipes Beardsley, originally found on Hawaii and on Australasian islands, was recently discovered on a southwestern island (Ishigaki Island) of Japan. Because D. neobrevipes is known to attack many fruits and other crops, it is essential to establish a strategy to prevent t...
[ "Synthetic Chemistry and Materials", "Physical and Analytical Chemical Sciences", "Environmental Biology, Ecology and Evolution" ]
10.1007/JHEP11(2016)151
K Decompositions And 3D Gauge Theories
This paper combines several new constructions in mathematics and physics. Mathematically, we study framed flat PGL(K, ℂ)-connections on a large class of 3-manifolds M with boundary. We introduce a moduli space ℒ K (M) of framed flat connections on the boundary ∂M that extend to M. Our goal is to understand an open p...
[ "Fundamental Constituents of Matter", "Mathematics" ]
10.1038/srep41228
Using the MitoB method to assess levels of reactive oxygen species in ecological studies of oxidative stress
In recent years evolutionary ecologists have become increasingly interested in the effects of reactive oxygen species (ROS) on the life-histories of animals. ROS levels have mostly been inferred indirectly due to the limitations of estimating ROS from in vitro methods. However, measuring ROS (hydrogen peroxide, H2 O2) ...
[ "Environmental Biology, Ecology and Evolution", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1145/2544173.2509530
Class Hierarchy Complementation
We present the problem of class hierarchy complementation: given a partially known hierarchy of classes together with subtyping constraints ("A has to be a transitive subtype of B") complete the hi. . .
[ "Computer Science and Informatics" ]
3739803
Revisiting europeanization in southeast europe. an historical approach
The future of Europe will vitally depend on its ability to transform and unify the continent. Southeast Europe, with its complex historical trajectories and its own particularistic Europeanness, has been labelled difficult to Europeanize. Yet, Europeanization in Southeast Europe has a far longer history reaching back i...
[ "The Study of the Human Past", "Institutions, Governance and Legal Systems" ]
W2751418033
Redox Controls over the Stability of U(IV) in Floodplains of the Upper Colorado River Basin
Aquifers in the Upper Colorado River Basin (UCRB) exhibit persistent uranium (U) groundwater contamination plumes originating from former ore processing operations. Previous observations at Rifle, Colorado, have shown that fine grained, sulfidic, organic-enriched sediments accumulate U in its reduced form, U(IV), which...
[ "Earth System Science", "Physical and Analytical Chemical Sciences" ]
10.1063/1.5063986
Boundary Triples For The Dirac Operator With Coulomb Type Spherically Symmetric Perturbations
We determine explicitly a boundary triple for the Dirac operator H≔−iα⋅∇+mβ+V(x) in R3, for m∈R and V(x)=|x|−1(νI4+μβ−iλα⋅x/|x| β), with ν,μ,λ∈R. Consequently, we determine all the self-adjoint realizations of H in terms of the behavior of the functions of their domain in the origin. When supx|x||V(x)|≤1, we discuss th...
[ "Mathematics", "Fundamental Constituents of Matter" ]
interreg_3120
Risk communication strategies
The concept of risk management includes a wide range of measures, which deal with natural hazards and which are divided into different topics such as prevention, protection, preparation, event management and reconstruction. A correct risk perception in the population and an efficient communication of risks, build up an...
[ "Earth System Science", "The Social World and Its Interactions", "Human Mobility, Environment, and Space" ]
W2770676323
Mass Spectrometry Imaging: A Review of Emerging Advancements and Future Insights
Mass spectrometry imaging (MSI) is a powerful tool that enables untargeted investigations into the spatial distribution of molecular species in a variety of samples. It has the capability to image thousands of molecules, such as metabolites, lipids, peptides, proteins, and glycans, in a single experiment without labeli...
[ "Physical and Analytical Chemical Sciences", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
W4312510093
Residência de Medicina de Família e Comunidade: percepções de egressos sobre sua formação e processo de trabalho
Analisou-se como as residências de Medicina de Família e Comunidade (RMFC) de uma capital da região norte do Brasil contribuíram para a formação e o desenvolvimento do atual processo de trabalho de seus egressos. Estudo exploratório, descritivo e transversal, com abordagem qualitativa focada em 31 egressos por meio de ...
[ "Prevention, Diagnosis and Treatment of Human Diseases", "The Social World and Its Interactions" ]
W2565693063
Technical efficiency and its determinants of the various cropping systems in the purple-soiled, hilly region of southwestern China
This study examines the technical efficiency (TE) differences among typical cropping systems of smallholder farmers in the purple-soiled hilly region of southwestern China. Household-, plot-, and crop- level data and community surveys were conducted to explore TE levels and determinants of typical cropping systems by u...
[ "Products and Processes Engineering", "Earth System Science" ]
692891
Simulating Non-Equilibrium Dynamics of Atmospheric Multicomponent Clusters
Atmospheric aerosol particles play a key role in regulating the climate, and particulate matter is responsible for most of the 7 million deaths per year attributed to air pollution. Lack of understanding of aerosol processes, especially the formation of ice crystals and secondary particles from condensable trace gases,...
[ "Earth System Science", "Physical and Analytical Chemical Sciences", "Condensed Matter Physics", "Computer Science and Informatics" ]
W2512639264
First magmatism in the New England Batholith, Australia: forearc and arc–back-arc components in the Bakers Creek Suite gabbros
Abstract. The New England Orogen, eastern Australia, was established as an outboard extension of the Lachlan Orogen through the migration of magmatism into forearc basin and accretionary prism sediments. Widespread S-type granitic rocks of the Hillgrove and Bundarra supersuites represent the first pulse of magmatism, f...
[ "Earth System Science" ]
Q3272715
USS
Zweck und Ziel des FEI-Projekts ist die Entwicklung eines neuen Systems zur Selbstabschottung der Abdeckungen verschiedener Geräte und Geräte, die zur Verwendung in Einzelhandelsgeräten für den Vertrieb von Lebensmitteln bestimmt sind.
[ "Products and Processes Engineering" ]
10.1375/twin.15.2.158
Causes of Comorbidity: Pleiotropy or Causality? Shared Genetic and Environmental Influences on Migraine and Neuroticism
Comorbidity — the clustered occurrence of two traits or disorders — may be studied in genetically informative designs such as the classical twin study, to test whether genetic and/or environmental factors underlying the two disorders are correlated. When a genetic correlation is found, this can be explained by several ...
[ "Neuroscience and Disorders of the Nervous System", "Integrative Biology: from Genes and Genomes to Systems" ]
10.1007/978-3-319-10879-7_23
An Empirical Study And Some Improvements Of The Minimac Protocol For Secure Computation
Recent developments in Multi-party Computation (MPC) has resulted in very efficient protocols for dishonest majority in the preprocessing model. In particular, two very promising protocols for Boolean circuits have been proposed by Nielsen et al. (nicknamed TinyOT) and by Damgard and Zakarias (nicknamed MiniMac). While...
[ "Computer Science and Informatics", "Systems and Communication Engineering" ]
616823
Attosecond physics at nanoscale metal tips - strong field physics in the near-field optics regime
Electron dynamics in metals and nanostructures take place on attosecond timescales. Until today, these extremely fast processes are little understood let alone utilized. With NearFieldAtto, strong-field driven phenomena at nanoscale metal structures will be explored to elucidate collective electron dynamics and to indu...
[ "Fundamental Constituents of Matter", "Condensed Matter Physics", "Physical and Analytical Chemical Sciences" ]
EA 201690417 A
СИСТЕМА ПЛАВУЧЕГО БАССЕЙНА И СПОСОБЫ ОБРАБОТКИ ВОДЫ В ПЛАВУЧЕМ БАССЕЙНЕ
Изобретение относится к плавучим бассейнам и к обработке воды в таких бассейнах. Изобретение также относится к большим плавучим бассейнам, которые могут быть установлены в природном или искусственном водоеме для улучшения характеристик воды, которые являются непригодными для рекреационного использования. Плавучий бассе...
[ "Products and Processes Engineering", "Environmental Biology, Ecology and Evolution" ]
3740492
Nanoscale aromaticity and supramolecular electronic materials
ARO-MAT will target emergent cooperative electronic and magnetic phenomena in molecules with dimensions of 5–25 nm (i.e. as big as many proteins). The project will develop supramolecular architectures with large pi-systems and well-defined geometries, in which the frontier orbitals coherently delocalize charge over the...
[ "Condensed Matter Physics", "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials" ]
10.5194/gmd-2015-225
PMCAMx-2015 evaluation over Europe against AERONET and MODIS aerosol optical depth measurements
Abstract. The ability of the chemical transport model (CTM) PMCAMx to reproduce aerosol optical depth (AOD) measurements by the Aerosol Robotic Network (AERONET) and the Moderate Resolution Imaging Spectroradiometer (MODIS) over Europe during a photochemically active period is evaluated. Periods with high dust levels a...
[ "Physical and Analytical Chemical Sciences", "Earth System Science" ]
10.1016/j.cell.2019.08.055
R Loops: From Physiological to Pathological Roles
DNA-RNA hybrids play a physiological role in cellular processes, but often, they represent non-scheduled co-transcriptional structures with a negative impact on transcription, replication and DNA repair. Accumulating evidence suggests that they constitute a source of replication stress, DNA breaks and genome instabilit...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Cell Biology, Development, Stem Cells and Regeneration", "Integrative Biology: from Genes and Genomes to Systems" ]
260927
Population transcriptional genomics in humans using high throughput sequencing
Gene expression is one of the marks of cellular state and function. The relative abundance of transcripts defines and is a result of the differentiation status of a cell. Interrogation of gene expression levels and patterns in the human and other genomes can be informative about perturbations from the average pattern...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Cell Biology, Development, Stem Cells and Regeneration", "Integrative Biology: from Genes and Genomes to Systems" ]
10.1073/pnas.1907799117
Chitin perception in plasmodesmata characterizes submembrane immune-signaling specificity in plants
The plasma membrane (PM) is composed of heterogeneous subdomains, characterized by differences in protein and lipid composition. PM receptors can be dynamically sorted into membrane domains to underpin signaling in response to extracellular stimuli. In plants, the plasmodesmal PM is a discrete microdomain that hosts sp...
[ "Immunity, Infection and Immunotherapy", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1080/00107514.2015.1125624
Conditional And Unconditional Gaussian Quantum Dynamics
This article focuses on the general theory of open quantum systems in the Gaussian regime and explores a number of diverse ramifications and consequences of the theory. We shall first introduce the Gaussian framework in its full generality, including a classification of Gaussian (also known as "general-dyne") quantum m...
[ "Fundamental Constituents of Matter", "Mathematics" ]
320620
The calm before the storm: Pre-stellar cores as Astrophysical Laboratories
Stars like our Sun and planets like our Earth form in dense regions within interstellar molecular clouds, called pre-stellar cores (PSCs). PSCs provide the initial conditions in the process of star and planet formation, but large uncertainties exist concerning basic astrophysical processes and parameters, such as surf...
[ "Universe Sciences", "Physical and Analytical Chemical Sciences" ]
W2512715980
COST OF INTENSIVE CARE IN INDIA
Objectives: The majority of patients in India access private sector providers for curative medical services. However, there is scanty information on the cost of treatment of critically ill patients in this setting. The study evaluates the cost and extent of financial subsidy required for patients admitted to an intensi...
[ "Prevention, Diagnosis and Treatment of Human Diseases", "Individuals, Markets and Organisations" ]
10.1073/pnas.1807750115
Mechanics of elastomeric molecular composites
A classic paradigm of soft and extensible polymer materials is the difficulty of combining reversible elasticity with high fracture toughness, in particular for moduli above 1 MPa. Our recent discovery of multiple network acrylic elastomers opened a pathway to obtain precisely such a combination. We show here that they...
[ "Condensed Matter Physics", "Materials Engineering" ]
Q2889302
Inizia a Basto
Il progetto Start In Basto consiste nella promozione di una serie di azioni volte a promuovere e promuovere l'imprenditorialità nella regione di Basto, che copre 6 comuni a bassa densità. Si tratta di territori con scarsa attrattività. Il progetto Star in Basto mira a creare nuove opportunità per il pubblico più svanta...
[ "Individuals, Markets and Organisations", "Human Mobility, Environment, and Space", "The Social World and Its Interactions" ]
W1983075410
Photoelectrocatalytic degradation of triclosan on TiO2 nanotube arrays and toxicity change
Triclosan, one of the most widely used disinfectants, has been found to be toxic to animals and human beings. In this paper, triclosan was degraded on TiO2 nanotube arrays, using a photoelectrocatalytic (PEC) process under UV illumination, with Na2SO4 as the supporting electrolyte. The effect of bias potential was inve...
[ "Physical and Analytical Chemical Sciences", "Environmental Biology, Ecology and Evolution" ]
895957
An avant-garde measuring principle based on the potentiometric method using signals from the kidney to monitor hospitalised patients water-volemic state
The need of high quality and cost-efficient hemodynamic and metabolic state monitoring devices is increasing exponentially, due to e.g. ageing population, chronic health conditions, health support system advance in developing courtiers and rural areas and the growing number of cases of chronic conditions in Europe and ...
[ "Products and Processes Engineering", "Prevention, Diagnosis and Treatment of Human Diseases" ]
10.1371/journal.pone.0193098
Identification of relevant drugable targets in diffuse large B-cell lymphoma using a genome-wide unbiased CD20 guilt-by association approach
Forty percent of patients with diffuse large B-cell lymphoma (DLBCL) show resistant disease to standard chemotherapy (CHOP) in combination with the anti-CD20 monoclonal antibody rituximab (R). Although many new anti-cancer drugs were developed in the last years, it is unclear which of these drugs can be safely combined...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Integrative Biology: from Genes and Genomes to Systems", "Prevention, Diagnosis and Treatment of Human Diseases" ]
10.1038/ncomms11032
Roquin recognizes a non-canonical hexaloop structure in the 3′-UTR of Ox40
The RNA-binding protein Roquin is required to prevent autoimmunity. Roquin controls T-helper cell activation and differentiation by limiting the induced expression of costimulatory receptors such as tumor necrosis factor receptor superfamily 4 (Tnfrs4 or Ox40). A constitutive decay element (CDE) with a characteristic t...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Immunity, Infection and Immunotherapy" ]
10.1038/ncomms9322
Expanding the biotechnology potential of lactobacilli through comparative genomics of 213 strains and associated genera
Lactobacilli are a diverse group of species that occupy diverse nutrient-rich niches associated with humans, animals, plants and food. They are used widely in biotechnology and food preservation, and are being explored as therapeutics. Exploiting lactobacilli has been complicated by metabolic diversity, unclear species...
[ "Integrative Biology: from Genes and Genomes to Systems", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Biotechnology and Biosystems Engineering" ]
10.3389/fncel.2015.00246
Reappraisal of Bergmann glial cells as modulators of cerebellar circuit function
Just as there is a huge morphological and functional diversity of neuron types specialized for specific aspects of information processing in the brain, astrocytes have equally distinct morphologies and functions that aid optimal functioning of the circuits in which they are embedded. One type of astrocyte, the Bergmann...
[ "Neuroscience and Disorders of the Nervous System", "Cell Biology, Development, Stem Cells and Regeneration" ]
W797422329
An Extensible Neuroimaging e-Repository for Clinical Trials of Paediatric Brain Tumours.
Novel imaging techniques are playing an increasing role in tumour characterisation, assessment and management. However, incorporating imaging data into clinical trials presents a number of challenges in terms of quality control, standardisation in data collection, interoperability of widely used archiving systems and e...
[ "Neuroscience and Disorders of the Nervous System", "Computer Science and Informatics", "Prevention, Diagnosis and Treatment of Human Diseases" ]
789240
The evolution of adaptive response mechanisms
In an era of rapid climate change there is a pressing need to understand whether and how organisms are able to adapt to novel environments. Such understanding is hampered by a major divide in the life sciences. Disciplines like systems biology or neurobiology make rapid progress in unravelling the mechanisms underlying...
[ "Environmental Biology, Ecology and Evolution", "Integrative Biology: from Genes and Genomes to Systems", "Computer Science and Informatics" ]
W2370099646
Using Lorenz Curve to Analyze Land Use Structure in Xinjiang Production and Construction Corps
Based on land use data from 1996 to 2009 in Xinjiang Production and Construction Corps,the quantitative analysis of land use structure was conducted by using Lorenz curve and Gini coefficients which were applied to measure property,the extent of the resource allocation.The results indicated that town village and indust...
[ "Earth System Science", "Mathematics" ]
10.1086/668058
The Coordinated Radio And Infrared Survey For High Mass Star Formation The Cornish Survey I Survey Design
We describe the motivation, design and implementation of the CORNISH survey, an arcsecond resolution radio continuum survey of the inner Galactic plane at 5GHz using the Karl G. Jansky Very Large Array (VLA). It is a blind survey co-ordinated with the northern Spitzer GLIMPSE I region covering 10 o < l <65 o and |b| <...
[ "Universe Sciences", "Systems and Communication Engineering" ]
10.1007/978-3-0348-0939-9_12
On Global Well Ill Posedness Of The Euler Poisson System
We discuss the problem of well-posedness of the Euler-Poisson system arising, for example, in the theory of semi-conductors, models of plasma and gaseous stars in astrophysics. We introduce the concept of dissipative weak solution satisfying, in addition to the standard system of integral identities replacing the origi...
[ "Mathematics", "Universe Sciences" ]
10.1051/0004-6361/201220019
The Pre Launch Planck Sky Model A Model Of Sky Emission At Submillimetre To Centimetre Wavelengths
We present the Planck Sky Model (PSM), a parametric model for the generation of all-sky, few arcminute resolution maps of sky emission at submillimetre to centimetre wavelengths, in both intensity and polarisation. Several options are implemented to model the cosmic microwave background, Galactic diffuse emission (sync...
[ "Universe Sciences", "Computer Science and Informatics", "Systems and Communication Engineering" ]