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W2215805880
$$\text {FI}_{\mathcal {W}}$$ FI W -modules and constraints on classical Weyl group characters
In this paper we study the characters of sequences of representations of any of the three families of classical Weyl groups $$\mathcal {W}_n$$ : the symmetric groups, the signed permutation groups (hyperoctahedral groups), or the even-signed permutation groups. Our results extend work of Church et al. (Duke Math J, 20...
[ "Mathematics" ]
10.1038/nmeth.4304
Fused cerebral organoids model interactions between brain regions
Human brain development involves complex interactions between different regions, including long-distance neuronal migration or formation of major axonal tracts. Different brain regions can be cultured in vitro within 3D cerebral organoids, but the random arrangement of regional identities limits the reliable analysis o...
[ "Neuroscience and Disorders of the Nervous System", "Cell Biology, Development, Stem Cells and Regeneration" ]
10.1126/science.aaw6985
Cancer modeling meets human organoid technology
Organoids are microscopic self-organizing, three-dimensional structures that are grown from stem cells in vitro. They recapitulate many structural and functional aspects of their in vivo counterpart organs. This versatile technology has led to the development of many novel human cancer models. It is now possible to cre...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Physiology in Health, Disease and Ageing" ]
W2008285096
Re-visitation Choice Impacts of Consideration on Sustainable Tourism Development - Using Logit and Probit Models -
Re-visitation have an effect on dependent variables of regional tourism demand model. This study focused on the re-visitation impacts of consideration on sustainable tourism development of tourists as a new factors of tourism. Based on literature reviews, 11 variables were selected, a questionnaire survey was given to ...
[ "Individuals, Markets and Organisations", "Human Mobility, Environment, and Space" ]
10.1038/nrm3133
A blueprint for kinetochores - New insights into the molecular mechanics of cell division
Kinetochores are large proteinaceous complexes that physically link centromeric DNA to the plus ends of spindle microtubules. Stable kinetochore-microtubule attachments are a prerequisite for the accurate and efficient distribution of genetic material over multiple generations. In the past decade, concerted research ha...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
336978
Light Field Imaging and Analysis
One of the most fundamental challenges in computer vision is to reliably establish correspondence - how to match a location in one image to its counterpart in another. It lies at the heart of numerous important problems, for example stereo, optical flow, tracking and the reconstruction of scene geometry from several ph...
[ "Computer Science and Informatics", "Systems and Communication Engineering" ]
W1969262766
Evaluation of PHBHHx and PHBV/PLA fibers used as medical sutures
Two types of fibers were prepared by using bio-based materials: a mono-filament made from poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) (PHBHHx) and a multi-filament made from poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) and polylactic acid (PLA) blend. The two fibers were evaluated for mechanical properties, bi...
[ "Materials Engineering", "Prevention, Diagnosis and Treatment of Human Diseases", "Synthetic Chemistry and Materials" ]
US 9504122 W
LEATHER-LIKE HOOF PAD OF COMPOSITE MATERIAL
This invention is a hoof pad (10, 20) adapted for attachment between the hoof (32) of a horse and a horseshoe (34). The hoof pad (10, 20) is made of a leather-like composite material having a substantially continuous web portion impregnated with a binder composition. The web portion of the composite material is made of...
[ "Materials Engineering", "Synthetic Chemistry and Materials" ]
CA 2022051306 W
SYSTEM AND METHOD FOR SEMI-SUPERVISED VIDEO-DRIVEN FACIAL ANIMATION TRANSFER
A method transfers facial expressions from a performance input to a 3D CG character. The method comprises: providing an inference engine trained for receiving, as input, images exhibiting facial expressions and outputting, for each input image, a 3D CG representation of a CG character having a character facial expressi...
[ "Computer Science and Informatics" ]
10.1098/rspb.2012.2564
The role of individuality in collective group movement
How different levels of biological organization interact to shape each other's function is a central question in biology. One particularly important topic in this context is how individuals' variation in behaviour shapes group-level characteristics. We investigated how fish that express different locomotory behaviour i...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Integrative Biology: from Genes and Genomes to Systems" ]
10.3389/fimmu.2017.01854
Tetraspanin CD9 limits mucosal healing in experimental colitis
Tetraspanins are a family of proteins with four transmembrane domains that associate between themselves and cluster with other partner proteins, conforming a distinct class of membrane domains, the tetraspanin-enriched microdomains (TEMs). These TEMs constitute macromolecular signaling platforms that regulate key proce...
[ "Immunity, Infection and Immunotherapy", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Cell Biology, Development, Stem Cells and Regeneration", "Physiology in Health, Disease and Ageing" ]
10.1088/0264-9381/33/12/125022
Superradiant Instabilities Of Asymptotically Anti De Sitter Black Holes
We study the linear stability of asymptotically anti–de Sitter black holes in general relativity in spacetime dimension d ≥ 4. Our approach is an adaptation of the general framework of Hollands and Wald, which gives a stability criterion in terms of the sign of the canonical energy, E . The general framework was origin...
[ "Fundamental Constituents of Matter", "Universe Sciences" ]
US 8701050 W
LIPOPOLYSACCHARIDE AND NATURAL FACTOR COMPOSITIONS FOR ANTI-TUMOR THERAPY AND METHOD OF TREATMENT
Bacterial lipopolysaccharide (LPS) can be used to induce release of factors into the serum enabling rejection of tumors and increasing the efficacy of added anti-tumor agents. Thus exogenous TNF, when used together with LPS or other factors induced by LPS can be used at lower non-toxic doses to cause tumor rejection. T...
[ "Immunity, Infection and Immunotherapy", "Prevention, Diagnosis and Treatment of Human Diseases" ]
10.1016/j.jconrel.2018.01.021
Stimuli-responsive nanocarriers for delivery of bone therapeutics – Barriers and progresses
The development of stimuli-responsive nanomedicines with tunable cargo release is gathering an increased applicability in bone regeneration and precision biomedicine. Yet, the formulation of nanocarriers that explore skeletal-specific stimuli remains remarkably challenging to materialize due to several endogenous and d...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Prevention, Diagnosis and Treatment of Human Diseases", "Materials Engineering" ]
10.1515/9783110365856
Space In Hellenistic Philosophy Critical Studies In Ancient Physics
The volume discusses the notion of space by focusing on the most representative exponents of the Hellenistic schools and explores the role played by spatial concepts in both coeval and later authors who, without specifically thematising these concepts, made use of them in a theoretically original way. Renowned scholars...
[ "Texts and Concepts" ]
10.1038/nature19333
Insights from biochemical reconstitution into the architecture of human kinetochores
Chromosomes are carriers of genetic material and their accurate transfer from a mother cell to its two daughters during cell division is of paramount importance for life. Kinetochores are crucial for this process, as they connect chromosomes with microtubules in the mitotic spindle. Kinetochores are multi-subunit compl...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Cell Biology, Development, Stem Cells and Regeneration" ]
10.4414/smw.2017.14523
Genetic determinants of the epigenome in development and cancer
Although we have detailed maps of epigenetic marks on DNA and chromatin for many cell types and disease states, the origin and significance of these patterns is incompletely understood. Deregulation of the epigenome is a frequent accompaniment to cancer, and it is therefore important that we learn how it contributes to...
[ "Integrative Biology: from Genes and Genomes to Systems", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
W2345432244
Influential Factors on the Consumption of Family Look Clothes
1) When parents and their children wear matching clothes, ranging from one item to the entire wardrobe, we call this the “family look.” The purpose of this study was to identify the factors that influence family look clothes consumption. It was proposed that mothers’ familism tendencies, playfulness, and demographic ch...
[ "The Social World and Its Interactions", "The Human Mind and Its Complexity", "Individuals, Markets and Organisations" ]
W2184969760
New Technology–based Firms – an exploratory study of technology exploitation and industrial renewal
This paper explores the role of new technology–based firms in the process of industrial renewal of Sweden by analyzing a set of such firms which were established in the period 1965–1974. We find that there has been an extensive trade in the technology base of these firms and a great deal of the transactions were made w...
[ "Individuals, Markets and Organisations" ]
EP 2011052710 W
A POLYMER USEFUL AS VISCOSITY INDEX IMPROVER
The present invention describes a polymer useful as viscosity index improver comprising units derived from one or more ethylenically unsaturated ester compounds of formula (I), where R is hydrogen or methyl, R1 means a linear, branched or cyclic alkyl residue with 1-6 carbon atoms, R2 and R3 independently represent hyd...
[ "Synthetic Chemistry and Materials", "Materials Engineering" ]
10.24917/20837276.8.9
The Televisual Framing Of Organ Transplantations In France From The 1960S To The 1980S
Since the first successful human organ transplants of the late 60s, television in France has represented a means of publicizing and then popularizing a surgical operation that is not self-evident in scientific terms or in terms of social acceptance. This paper intends to show how the televisual narrative on organ trans...
[ "Texts and Concepts", "The Study of the Human Past", "The Social World and Its Interactions", "Studies of Cultures and Arts" ]
W2108554366
“Top-Down” Effects Where None Should Be Found
A tidal wave of recent research purports to have discovered that higher-level states such as moods, action capabilities, and categorical knowledge can literally and directly affect how things look. Are these truly effects on perception, or might some instead reflect influences on judgment, memory, or response bias? Her...
[ "Neuroscience and Disorders of the Nervous System", "The Human Mind and Its Complexity" ]
10.1364/OE.22.026559
Active Terahertz Beam Steering By Photo Generated Graded Index Gratings In Thin Semiconductor Films
We demonstrate active beam steering of terahertz radiation using a photo-excited thin layer of gallium arsenide. A constant gradient of phase discontinuity along the interface is introduced by an spatially inhomogeneous density of free charge carriers that are photo-generated in the GaAs with an optical pump. The optic...
[ "Condensed Matter Physics", "Systems and Communication Engineering" ]
864965
Predictions and Observations for Discs: Planetary Cores and dust Aggregates from non-ideal MHD Simulations with radiative Transfer.
One of the most fascinating and challenging question of Modern Astrophysics is: How do planets form? Indeed, micronic dust grains must grow over 30 orders of magnitude in mass to build planet cores. Global numerical simulations of dust grains that couple the dynamics of the particles to their growth/fragmentation and t...
[ "Universe Sciences", "Computer Science and Informatics" ]
W177642614
Low back pain radiating to the leg: an atypical cause.
This study reports the case of a 47-year old female with low back pain radiating to groin and anterior regions of the left thigh and leg. At symptoms onset, electromyography showed left L3-L4 radiculopathy, and nuclear magnetic resonance revealed disc protrusion at the same level with impingement of the spinal nerve ro...
[ "Physiology in Health, Disease and Ageing", "Immunity, Infection and Immunotherapy" ]
10.1371/journal.pone.0083633
Increased mortality exposure within the family rather than individual mortality experiences triggers faster life-history strategies in historic human populations
Life History Theory predicts that extrinsic mortality risk is one of the most important factors shaping (human) life histories. Evidence from contemporary populations suggests that individuals confronted with high mortality environments show characteristic traits of fast life-history strategies: they marry and reproduc...
[ "The Study of the Human Past", "Environmental Biology, Ecology and Evolution" ]
10.1016/j.visres.2014.08.017
Dissociation between spatial and temporal integration mechanisms in Vernier fusion
The visual system constructs a percept of the world across multiple spatial and temporal scales. This raises the questions of whether different scales involve separate integration mechanisms and whether spatial and temporal factors are linked via spatio-temporal reference frames. We investigated this using Vernier fusi...
[ "Neuroscience and Disorders of the Nervous System" ]
10.1039/C6SM02390H
Oil In Water Microfluidics On The Colloidal Scale New Routes To Self Assembly And Glassy Packings
We have developed Norland Optical Adhesive (NOA) flow focusing devices, making use of the excellent solvent compatibility and surface properties of NOA to generate micron scale oil-in-water emulsions with polydispersities as low as 5%. While current work on microfluidic oil-in-water emulsification largely concerns the ...
[ "Condensed Matter Physics", "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials" ]
10.1186/1556-276x-7-197
Synthesis and field emission properties of different ZnO nanostructure arrays
Abstract In this article, zinc oxide (ZnO) nanostructures of different shapes were fabricated on silicon substrate. Well-aligned and long ZnO nanowire (NW) arrays, as well as leaf-like ZnO nanostructures (which consist of modulated and single-phase structures), were fabricated by a chemical vapor deposition (CVD) metho...
[ "Condensed Matter Physics", "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials", "Materials Engineering" ]
FR 2010051184 W
SYSTEM FOR THE OVERALL CONTROL OF HEAT FOR ELECTRICALLY PROPELLED MOTOR VEHICLE
The invention relates to a system (10) for the overall control of heat for the passenger compartment (33) and for the electrical units in a motor vehicle that is completely or partially propelled by an electric engine powered by a battery, including a heat-control fluid circuit (3) coupled to a heating means (27) and/o...
[ "Products and Processes Engineering", "Systems and Communication Engineering" ]
EP 2014075432 W
METHOD FOR OPERATING A NOISE-EMITTING INSTALLATION AND INSTALLATION FOR PERFORMING THE METHOD
The invention relates to a method for operating a noise-emitting installation (11), which emits noise subject to noise protection provisions into the environment at specifiable times in the form of operationally determined noise events that each extend over a certain time period, the emission of noise being distributed...
[ "Systems and Communication Engineering", "Products and Processes Engineering" ]
10.1177/1088868316657965
Functional Interdependence Theory An Evolutionary Account Of Social Situations
Social interactions are characterized by distinct forms of interdependence, each of which has unique effects on how behavior unfolds within the interaction. Despite this, little is known about the psychological mechanisms that allow people to detect and respond to the nature of interdependence in any given interaction....
[ "The Human Mind and Its Complexity", "The Social World and Its Interactions" ]
176197
Intensified by design® for the intensification of processes involving solids handling
IbD® will create a holistic platform for facilitating process intensification in processes in which solids are an intrinsic part, the cornerstone of which will be an intensified-by-design® (IbD). The IbD approach is hinged on the use of robust data about a process to ‘redesign’, modify, adapt and alter that process in ...
[ "Products and Processes Engineering", "Materials Engineering", "Physical and Analytical Chemical Sciences" ]
Q4785902
DOTT. ING. GIULIANO BOERO
THE PROFESSIONAL FIRM DEALS WITH THE DESIGN AND MANAGEMENT OF WORKS OF MECHANICAL SYSTEMS, ADVICE ON FIRE PREVENTION AND SAFETY IN THE WORKPLACE. IT CONSISTS OF A FREELANCER AND VARIOUS EXTERNAL COLLABORATORS. THE DIGITISATION OF THE OFFICE STRUCTURE WOULD FAVOUR SMART WORKING WITH THE POSSIBILITY OF ACCESS TO THE OFFI...
[ "Products and Processes Engineering", "Computer Science and Informatics" ]
10.1145/2766950
Isotopic Approximation Within A Tolerance Volume
We introduce in this paper an algorithm that generates from an input tolerance volume a surface triangle mesh guaranteed to be within the tolerance, intersection free and topologically correct. A pliant meshing algorithm is used to capture the topology and discover the anisotropy in the input tolerance volume in order ...
[ "Computer Science and Informatics", "Mathematics" ]
2717406
Probing the mysteries of sweet “on-off” switches of the human immune system: toward the development of novel glycomimetics against bacterial infections
Glycans are directly involved in the normal physiology and in the etiology of several major diseases, spanning from bacterial and viral infections through to cancer and autoimmune disorders. Thus, deciphering the glycome holds huge promise to provide new targets and diagnostics for human health. Despite the tremendou...
[ "Immunity, Infection and Immunotherapy", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Synthetic Chemistry and Materials", "Physical and Analytical Chemical Sciences" ]
802923
From Evolution to Clockworks:Unravelling the molecular basis of circalunar clocks
Circalunar clocks are endogenous biological clocks, which allow organisms to time development and reproduction to lunar phase. They are common in marine organisms, but their molecular basis is still entirely unknown. Candidate gene approaches have failed so far. In the marine midge Clunio marinus (Diptera: Chironomidae...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Environmental Biology, Ecology and Evolution", "Integrative Biology: from Genes and Genomes to Systems" ]
10.1021/jp400958f
Nuclear spin symmetry conservation and relaxation in water ( <sup>1</sup>H<inf>2</inf><sup>16</sup>O) studied by cavity ring-down (CRD) spectroscopy of supersonic jets
We report high resolution near-infrared laser spectra of water seeded in a supersonic jet expansion of argon probed by cavity ring-down spectroscopy (CRDS) in the R branch of the 2ν3 band (above 7500 cm-1) at several effective temperatures T < 30 K. Our goal is to study nuclear spin symmetry conservation and relaxatio...
[ "Physical and Analytical Chemical Sciences", "Fundamental Constituents of Matter" ]
10.1109/TPAMI.2014.2343235
Non Rigid Graph Registration Using Active Testing Search
We present a new approach for matching sets of branching curvilinear structures that form graphs embedded in ${\mathbb {R}}^2$ or ${\mathbb {R}}^3$ and may be subject to deformations. Unlike earlier methods, ours does not rely on local appearance similarity nor does require a good initial alignment. Furthermore, it can...
[ "Computer Science and Informatics" ]
220115
Galois representations and diophantine problems
Wiles' remarkable proof of Fermat's Last Theorem paved the way for the modular approach to Diophantine equations. This associates a Frey elliptic curve to a putative solution of a Diophantine equation and studies it using Galois representations and modularity. This proposal is organized around two research programmes, ...
[ "Mathematics" ]
US 9708504 W
SATIN AND TINTED SATIN IRIDESCENT FILMS
This invention provides a thermoplastic multilayer resinous film in which two or more resinous materials form a plurality of very thin layers of substantially uniform thickness, the layers being substantially parallel, the contiguous adjacent layers being of different transparent thermoplastic resinous materials differ...
[ "Synthetic Chemistry and Materials", "Materials Engineering" ]
W2382146853
Shanghai FTA's Impact on Commercial Banks and Strategy
Shanghai FTA has important strategic significance. It is the realization of China miracle second season,the higher level of the active liberalization measure. Implementing regulatory model change,trade transformation and upgrading,financial institutional innovation of the three dividend for China's economic development...
[ "Individuals, Markets and Organisations", "Institutions, Governance and Legal Systems" ]
10.1039/C5CC07602A
Reaction Of Diazocompounds With C70 Unprecedented Synthesis And Characterization Of Isomeric 5 6 Fulleroids
The synthesis of a variety of PCBM-type [5,6]-fulleroids and their further highly selective photoisomerization to the respective [6,6]-methanofullerenes is presented. Interestingly, the chemical reactivity of [5,6]-fulleroids reveals the same trend (a > b > c > d) to that observed for pristine C70 (α > β > γ > δ).
[ "Physical and Analytical Chemical Sciences", "Synthetic Chemistry and Materials" ]
10.3389/fcell.2018.00104
Hypoxia and selective autophagy in cancer development and therapy
Low oxygen availability, a condition known as hypoxia, is a common feature of various pathologies including stroke, ischemic heart disease, and cancer. Hypoxia adaptation requires coordination of intricate pathways and mechanisms such as hypoxia-inducible factors (HIFs), the unfolded protein response (UPR), mTOR, and a...
[ "Cell Biology, Development, Stem Cells and Regeneration", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Physiology in Health, Disease and Ageing" ]
10.1038/nrurol.2016.26
Current use of PSMA-PET in prostate cancer management
Currently, the findings of imaging procedures used for detection or staging of prostate cancer depend on morphology of lymph nodes or bone metabolism and do not always meet diagnostic needs. Prostate-specific membrane antigen (PSMA), a transmembrane protein that has considerable overexpression on most prostate cancer c...
[ "Prevention, Diagnosis and Treatment of Human Diseases", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Physical and Analytical Chemical Sciences" ]
W2093359839
Channel estimation method using power control schemes in wireless systems
Green communication is a new paradigm of designing the communication system which considers not only the processing performance but also the energy efficiency. Power control management is one of the approaches in green communication to reduce the power consumption in distributed communication system. In this paper, we ...
[ "Systems and Communication Engineering" ]
10.1126/science.1238025
Technical Comment on “The Placental Mammal Ancestor and the Post–K-Pg Radiation of Placentals”
O’Leary et al. (Research Article, 8 February 2013, p. 662) examined mammalian relationships and divergence times and concluded that a single placental ancestor crossed the Cretaceous-Paleogene (K-Pg) boundary. This conclusion relies on phylogenetic analyses that fail to discriminate between homology and homoplasy and ...
[ "Environmental Biology, Ecology and Evolution", "Integrative Biology: from Genes and Genomes to Systems" ]
W1887061577
Gamma Irradiation and In vitro Selection Could Increase Drought Tolerance in Sugarcane
Drought is one of the problems that decrease sugarcane productivity. Therefore it needs to develop a new drought tolerant sugarcane variety. The objectives of this research were to evaluate the response of gamma irradiated calli and drought tolerant of putative mutants through in vitro and in vivo selection . Kidang Ke...
[ "Biotechnology and Biosystems Engineering", "Environmental Biology, Ecology and Evolution" ]
10.1098/rsbl.2015.0509
Is domestication driven by reduced fear of humans? Boldness, metabolism and serotonin levels in divergently selected red junglefowl (Gallus gallus)
Domesticated animals tend to develop a coherent set of phenotypic traits. Tameness could be a central underlying factor driving this, and we therefore selected red junglefowl, ancestors of all domestic chickens, for high or low fear of humans during six generations. We measured basal metabolic rate (BMR), feed efficien...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Integrative Biology: from Genes and Genomes to Systems", "Environmental Biology, Ecology and Evolution" ]
Q4242014
MELHORIA DO PROCESSO DE PRODUÇÃO PARA A REALIZAÇÃO DE PORTAS E JANELAS
L — A INTRODUÇÃO DE MÁQUINAS INOVADORAS E NOVAS FERRAMENTAS PERMITIRÁ QUE A EMPRESA INICIE UM PROCESSO DE INOVAÇÃO NA EMPRESA, O QUE MELHORARÁ OS TEMPOS DE PRODUÇÃO, BEM COMO AUMENTARÁ A QUALIDADE E O ACABAMENTO DAS PORTAS E JANELAS REALIZADAS.
[ "Products and Processes Engineering" ]
10.1007/978-3-030-47491-1_20
A Shell Finite Element Model For Superelasticity Of Shape Memory Alloys
A finite element formulation for the analysis of large strains of thin-walled shape memory alloys is briefly presented. For the shell model we use a seven-kinematic-parameter model for large deformations and rotations, which takes into account the through-the-thickness stretch and can directly incorporate a fully 3D in...
[ "Condensed Matter Physics", "Materials Engineering" ]
10.1111/1468-2427.12725
Grabbed Urban Landscapes: Socio-spatial Tensions in Green Infrastructure Planning in Medellín
Cities confronted with unsustainable development and climatic changes are increasingly turning to green infrastructure as an approach for growth and climate risk management. In this context, recent scholarly attention has been paid to gentrification, real-estate speculation and resident displacement in the context of s...
[ "Human Mobility, Environment, and Space", "Environmental Biology, Ecology and Evolution" ]
10.1039/C9NR03009C
Anisotropic Buckling Of Few Layer Black Phosphorus
When a two-dimensional material, adhered onto a compliant substrate, is subjected to compression it can undertake a buckling instability yielding to a periodic rippling. Interestingly, when black phosphorus flakes are compressed along the zig-zag crystal direction the flake buckles forming ripples with a 40% longer per...
[ "Condensed Matter Physics", "Materials Engineering" ]
10.1038/s41598-020-57710-7
CREBBP and WDR 24 Identified as Candidate Genes for Quantitative Variation in Red-Brown Plumage Colouration in the Chicken
AbstractPlumage colouration in birds is important for a plethora of reasons, ranging from camouflage, sexual signalling, and species recognition. The genes underlying colour variation have been vital in understanding how genes can affect a phenotype. Multiple genes have been identified that affect plumage variation, bu...
[ "Integrative Biology: from Genes and Genomes to Systems", "Environmental Biology, Ecology and Evolution" ]
10.1088/1367-2630/18/1/013026
Modeling The Collective Magnetic Behavior Of Highly Packed Arrays Of Multi Segmented Nanowires
A powerful model to evaluate the collective magnetic response of large arrays of segmented nanowires comprising two magnetic segments of dissimilar coercivity separated by a non-magnetic spacer is introduced. The model captures the essential aspects of the underlying physics in these systems while being at the same tim...
[ "Condensed Matter Physics", "Materials Engineering" ]
10.1038/nprot.2012.028
Using bleach-chase to measure protein half-lives in living cells
Protein removal has a central role in numerous cellular processes. Obtaining systematic measurements of multiple protein removal rates is necessary to understand the principles that govern these processes, but it is currently a major technical challenge. To address this, we developed 'bleach-chase', a noninvasive metho...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Cell Biology, Development, Stem Cells and Regeneration", "Physical and Analytical Chemical Sciences", "Computer Science and Informatics" ]
10.1103/PhysRevLett.109.018702
Heterogeneous connections induce oscillations in large-scale networks
Realistic large-scale networks display a heterogeneous distribution of connectivity weights that might also randomly vary in time. We show that, depending on the level of heterogeneity in the connectivity coefficients, different qualitative macroscopic and microscopic regimes emerge. We evidence, in particular, generic...
[ "Mathematics", "Condensed Matter Physics", "Computer Science and Informatics" ]
10.1186/s40168-018-0445-0
Microbial interactions within the plant holobiont
Since the colonization of land by ancestral plant lineages 450 million years ago, plants and their associated microbes have been interacting with each other, forming an assemblage of species that is often referred to as a "holobiont. " Selective pressure acting on holobiont components has likely shaped plant-associated...
[ "Environmental Biology, Ecology and Evolution", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
W2916952475
Chronology and phenomenology of the 1982 and 2015 Wolf volcano eruptions, Galápagos Archipelago
Abstract The 1982 and 2015 eruptions were the first at Wolf volcano, Galapagos Archipelago, with eyewitness accounts and satellite imagery. Both eruptions were characterized by a rapid and intense initial phase, with multiple eruptive vents, leading to the formation of large ‘a‘ā lava fields and scarce pāhoehoe mostly ...
[ "Earth System Science" ]
FR 0202627 W
NOVEL METHOD FOR SYNTHESIS OF (2S, 3AS, 7AS)-1-[(S)-ALANYL]-OCTAHYDRO-1 H -INDOLE-2-CARBOXYLIC ACID DERIVATIVES AND USE FOR SYNTHESIS OF PERINDOPRIL
The invention concerns a method for industrial synthesis of compounds of formula (I), wherein: R1 represents a hydrogen atom or a linear or branched C1-C6 alkyl group or benzyl, and R2 represents a group protecting the amino function. The invention also concerns the use of same for industrial synthesis of perindopril o...
[ "Synthetic Chemistry and Materials", "Physical and Analytical Chemical Sciences", "Products and Processes Engineering" ]
10.1007/JHEP12(2010)014
Spiky Strings And Giant Holes
We analyse semiclassical strings in AdS in the limit of one large spin. In this limit, classical string dynamics is described by a finite number of collective coordinates corresponding to spikes or cusps of the string. The semiclassical spectrum consists of two branches of excitations corresponding to "large" and "smal...
[ "Fundamental Constituents of Matter", "Mathematics" ]
EP 13186105 A
Snowblower head for a brush cutter device
A snowblower fitting, comprising: a casing (2), provided with a front portion (21), through which the snow enters the casing (2) along an entry direction (A), and a rear portion (22), at which the snow exits from the casing (2); a rotor (3), predisposed to convey the snow from the entry portion (21) towards the rear po...
[ "Products and Processes Engineering" ]
215570
Era-Net cofund electric mobility europe
In collaboration with the European Commission and the European Green Vehicles Initiative Association, European countries and regions will set-up an ERA-NET Cofund to further promote electric mobility in Europe. Electric Mobility Europe builds on the experiences, networks and results of Electromobility+ and is designed ...
[ "Products and Processes Engineering", "Systems and Communication Engineering", "Human Mobility, Environment, and Space" ]
10.1109/TWC.2017.2706279
Feedback Mechanisms For Fdd Massive Mimo With D2D Based Limited Csi Sharing
Channel state information (CSI) feedback is a challenging issue in frequency division duplexing (FDD) massive MIMO systems. This paper studies a cooperative feedback scheme, where the users first exchange their CSI with each other through device-to-device (D2D) communications, then compute the precoder by themselves, a...
[ "Systems and Communication Engineering", "Computer Science and Informatics" ]
W2029217068
Localization of brain electrical activity sources and hemodynamic activity foci during motor imagery
Studied are sources of brain activity contributing to EEG patterns which correspond to motor imagery. The accuracy of their classification determines the efficiency of brain-computer interface (BCI) allowing for controlling external technical devices directly by brain signals without involving muscle activity. Sources ...
[ "Neuroscience and Disorders of the Nervous System", "Computer Science and Informatics" ]
10.1086/673497
How Life History Influences Population Dynamics In Fluctuating Environments
A major question in ecology is how age-specific variation in demographic parameters influences population dynamics. Based on long-term studies of growing populations of birds and mammals, we analyze population dynamics by using fluctuations in the total reproductive value of the population. This enables us to account f...
[ "Environmental Biology, Ecology and Evolution" ]
10.1371/journal.pgen.1007518
The last universal common ancestor between ancient Earth chemistry and the onset of genetics
All known life forms trace back to a last universal common ancestor (LUCA) that witnessed the onset of Darwinian evolution. One can ask questions about LUCA in various ways, the most common way being to look for traits that are common to all cells, like ribosomes or the genetic code. With the availability of genomes, w...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Integrative Biology: from Genes and Genomes to Systems", "Environmental Biology, Ecology and Evolution" ]
10.1161/CIRCULATIONAHA.117.029703
Microrna 146A As A Regulator Of Cardiac Energy Metabolism
Article, see p 747 The heart has a high mitochondrial content to generate the vast amount of ATP that is needed to provide the energy that is required for the continuous mechanical workload. Cellular ATP is predominantly used to support the contraction-relaxation cycle within the myocardium. Although cardiac mitochon...
[ "Physiology in Health, Disease and Ageing", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
10.1007/JHEP06(2017)119
Closing The Window For Compressed Dark Sectors With Disappearing Charged Tracks
We investigate the sensitivity at current and future hadron colliders to a heavy electrically-charged particle with a proper decay length below a centimetre, whose decay products are invisible due to below-threshold energies and/or small couplings to the Standard Model. A cosmologically-motivated example of a framework...
[ "Fundamental Constituents of Matter", "Universe Sciences" ]
724748
The functional interaction of EGFR and beta-catenin signalling in colorectal cancer: Genetics, mechanisms, and therapeutic potential.
Monoclonal antibodies against the EGF receptor (EGFR) provide substantive benefit to colorectal cancer (CRC) patients. However, no genetic lesions that robustly predict ‘addiction’ to the EGFR pathway have been yet identified. Further, even in tumours that regress after EGFR blockade, subsets of drug-tolerant cells oft...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Physiology in Health, Disease and Ageing", "Integrative Biology: from Genes and Genomes to Systems" ]
10.1002/2014RG000464
Future Changes To The Intensity And Frequency Of Short Duration Extreme Rainfall
Evidence that extreme rainfall intensity is increasing at the global scale has strengthened considerably in recent years. Research now indicates that the greatest increases are likely to occur in short-duration storms lasting less than a day, potentially leading to an increase in the magnitude and frequency of flash fl...
[ "Earth System Science" ]
10.1126/science.aad0189
Systems proteomics of liver mitochondria function
Recent improvements in quantitative proteomics approaches, including Sequential Window Acquisition of all Theoretical Mass Spectra (SWATH-MS), permit reproducible large-scale protein measurements across diverse cohorts. Together with genomics, transcriptomics, and other technologies, transomic data sets can be generate...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Integrative Biology: from Genes and Genomes to Systems", "Physiology in Health, Disease and Ageing" ]
10.1093/mnras/stz3173
Slingshot prominences: coronal structure, mass loss and spin down
Abstract The structure of a star’s coronal magnetic field is a fundamental property that governs the high-energy emission from the hot coronal gas and the loss of mass and angular momentum in the stellar wind. It is, however, extremely difficult to measure. We report a new method to trace this structure in rapidly-rota...
[ "Universe Sciences", "Physical and Analytical Chemical Sciences" ]
10.1007/s10494-017-9869-z
Adverse-Pressure-Gradient Effects on Turbulent Boundary Layers: Statistics and Flow-Field Organization
This manuscripts presents a study on adverse-pressure-gradient turbulent boundary layers under different Reynolds-number and pressure-gradient conditions. In this work we performed Particle Image Velocimetry (PIV) measurements supplemented with Large-Eddy Simulations in order to have a dataset covering a range of displ...
[ "Condensed Matter Physics", "Products and Processes Engineering" ]
interreg_1752
INterregional Ecosystem for entRepreneurship, ReseArch and Technology
In the past years, Countries have understood the importance to bet on innovative entrepreneurship, promoting the launch of companies based on the research activities of youngs, researchers, startuppers. However, in the territories involved in this Programme, the lack of funding and networking opportunities are hamperin...
[ "Individuals, Markets and Organisations", "Institutions, Governance and Legal Systems", "Human Mobility, Environment, and Space" ]
311363
Synthetic Metabolism in Plants: Elucidating Vinblastine Biosynthesis and Implementing Strategies to Overproduce Complex Plant Metabolites
Nature produces a spectacularly diverse array of complex molecules that are exploited for many applications. Elucidating the biosynthetic pathways that are used to construct these complex molecules allows implementation of metabolic engineering or synthetic biology strategies that can dramatically improve production le...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Biotechnology and Biosystems Engineering", "Integrative Biology: from Genes and Genomes to Systems" ]
W2060900710
Modeling Paying Behavior in Game Social Networks
Online gaming is one of the largest industries on the Internet, generating tens of billions of dollars in revenues annually. One core problem in online game is to find and convert free users into paying customers, which is of great importance for the sustainable development of almost all online games. Although much res...
[ "The Social World and Its Interactions", "Computer Science and Informatics" ]
10.1098/rspb.2011.0882
Evolution of a mimicry supergene from a multilocus architecture
The origin and evolution of supergenes have long fascinated evolutionary biologists. In the polymorphic butterfly Heliconius numata , a supergene controls the switch between multiple different forms, and results in near-perfect mimicry of model species. Here, we use a morphometric analysis to qu...
[ "Integrative Biology: from Genes and Genomes to Systems", "Environmental Biology, Ecology and Evolution", "Molecules of Life: Biological Mechanisms, Structures and Functions" ]
W1500558033
Scalability of robot swarms when applied to maze solving
Swarm robotics offers an intriguing approach to many real-world engineering problems. Such tasks that require covering a large search space or that involve working in potentially hazardous environments naturally lend themselves to robotic and/or swarm solutions. This research examines the effect of changing swarm size ...
[ "Computer Science and Informatics", "Systems and Communication Engineering" ]
10.1038/ncomms15859
All-optical observation and reconstruction of spin wave dispersion
To know the properties of a particle or a wave, one should measure how its energy changes with its momentum. The relation between them is called the dispersion relation, which encodes essential information of the kinetics. In a magnet, the wave motion of atomic spins serves as an elementary excitation, called a spin wa...
[ "Condensed Matter Physics", "Physical and Analytical Chemical Sciences", "Fundamental Constituents of Matter" ]
10.4337/9781788119962.00034
Direct Food Provisioning Collective Food Procurement
Direct food provisioning indicates any way of procuring food that does not conform to the ‘norm’ of individuals shopping in supermarkets, whereby consumers are placed at the receiving end of a long, complex, global food chain. This norm is not at all ‘normal’, since it is neither long-established nor sustainable. There...
[ "Environmental Biology, Ecology and Evolution", "The Social World and Its Interactions" ]
10.1038/s41396-018-0148-3
Fermentative Spirochaetes mediate necromass recycling in anoxic hydrocarbon-contaminated habitats
Spirochaetes are frequently detected in anoxic hydrocarbon- and organohalide-polluted groundwater, but their role in such ecosystems has remained unclear. To address this, we studied a sulfate-reducing, naphthalene-degrading enrichment culture, mainly comprising the sulfate reducer Desulfobacterium N47 and the rod-shap...
[ "Environmental Biology, Ecology and Evolution", "Earth System Science" ]
10.1097/PPO.0000000000000252
Identification Of Immunogenic Epitopes By Ms Ms
The interrogation of cell surface–presented immunogenic epitopes is of great importance to differentiate diseased cells in consequence to malignant transformation or viral infections. On the basis of this knowledge, next-generation immunotherapies against cancers, autoimmunity, or infectious diseases can be developed. ...
[ "Immunity, Infection and Immunotherapy", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Physical and Analytical Chemical Sciences" ]
220604
Modelling neuron-glia networks into a drug discovery platform for pain efficacious treatments - sofia ref.: 116072
Chronic Neuropathic Pain is frequently associated with peripheral nerve injury or disease. Peripheral injury activates both neuronal and glial components of the peripheral and central cellular circuitry. While it is widely known that the subsequently altered interactions between neurons and glial cells contribute to pa...
[ "Neuroscience and Disorders of the Nervous System", "Molecules of Life: Biological Mechanisms, Structures and Functions", "Prevention, Diagnosis and Treatment of Human Diseases" ]
10.1111/mmi.13235
PucC and LhaA direct efficient assembly of the light-harvesting complexes in Rhodobacter sphaeroides
The mature architecture of the photosynthetic membrane of the purple phototroph Rhodobacter sphaeroides has been characterised to a level where an atomic-level membrane model is available, but the roles of the putative assembly proteins LhaA and PucC in establishing this architecture are unknown. Here we investigate th...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Integrative Biology: from Genes and Genomes to Systems" ]
10.1021/acs.est.6b04919
Effect of Pellet Boiler Exhaust on Secondary Organic Aerosol Formation from α-Pinene
Interactions between anthropogenic and biogenic emissions, and implications for aerosol production, have raised particular scientific interest. Despite active research in this area, real anthropogenic emission sources have not been exploited for anthropogenic-biogenic interaction studies until now. This work examines t...
[ "Physical and Analytical Chemical Sciences", "Earth System Science" ]
10.1021/nl302166z
Reversible chiral switching of bis(phthalocyaninato) Terbium(III) on a metal surface
We demonstrate a reversible chiral switching of bis(phthalocyaninato) terbium(III) molecules on an Ir(111) surface by low temperature scanning tunneling microscopy. With an azimuthal rotation of its upper phthalocyanine ligand, the molecule can be switched between a chiral and an achiral configuration actuated by respe...
[ "Physical and Analytical Chemical Sciences", "Condensed Matter Physics" ]
10.1261/rna.061051.117
Avoidance of reporter assay distortions from fused dual reporters
Positioning test sequences between fused reporters permits monitoring of both translation levels and framing, before and after the test sequence. Many studies, including those on recoding such as productive ribosomal frameshifting and stop codon readthrough, use distinguishable luciferases or fluorescent proteins as re...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Integrative Biology: from Genes and Genomes to Systems" ]
W1987929095
Physiological Assessment and Allele Mining in Rice Cultivars for Salinity and Drought Stress Tolerance
Drought and salinity stresses badly influence rice plant growth and yield. The rising efforts to advance rice genotypes for drought and salt tolerance necessitate the selection of tolerant genotypes. Here, a total 51 rice genotypes were tested for salinity and moisture stress tolerance at germination and early seedling...
[ "Integrative Biology: from Genes and Genomes to Systems", "Environmental Biology, Ecology and Evolution", "Biotechnology and Biosystems Engineering" ]
10.1017/S0033291714003067
The Similarity Of The Structure Of Dsm Iv Criteria For Major Depression In Depressed Women From China The United States And Europe
Background Do DSM-IV diagnostic criteria for major depression (MD) in Chinese and Western women perform in a similar manner? Method The CONVERGE study included interview-based assessments of women of Han Chinese descent with treated recurrent MD. Using Mplus software, we investigated the overall degree of between-sampl...
[ "The Human Mind and Its Complexity", "Prevention, Diagnosis and Treatment of Human Diseases" ]
10.1016/j.immuni.2015.10.021
PI3 Kinase and FOXO1 Transcription Factor Activity Differentially Control B Cells in the Germinal Center Light and Dark Zones
Phosphatidylinositol 3' OH kinase (PI3K) signaling and FOXO transcription factors play opposing roles at several B cell developmental stages. We show here abundant nuclear FOXO1 expression in the proliferative compartment of the germinal center (GC), its dark zone (DZ), and PI3K activity, downregulating FOXO1, in the l...
[ "Molecules of Life: Biological Mechanisms, Structures and Functions", "Cell Biology, Development, Stem Cells and Regeneration", "Immunity, Infection and Immunotherapy" ]
10.1007/978-3-319-69299-9
Energy Poverty: (Dis)Assembling Europe's Infrastructural Divide
This open access book aims to consolidate and advance debates on European and global energy poverty by exploring the political and infrastructural drivers and implications of the condition across a variety of spatial scales. It highlights the need for a geographical conceptualization of the different ways in which hous...
[ "Human Mobility, Environment, and Space", "Institutions, Governance and Legal Systems", "The Social World and Its Interactions" ]
10.1145/2736283
Algorithmic Applications Of Baur Strassen S Theorem Shortest Cycles Diameter And Matchings
Consider a directed or an undirected graph with integral edge weights from the set [-W, W], that does not contain negative weight cycles. In this article, we introduce a general framework for solving problems on such graphs using matrix multiplication. The framework is based on the usage of Baur-Strassen’s theorem and ...
[ "Mathematics", "Computer Science and Informatics" ]
10.1212/wnl.0000000000004887
Comparing 18F-AV-1451 with CSF t-tau and p-tau for diagnosis of Alzheimer disease
ObjectiveTo compare PET imaging of tau pathology with CSF measurements (total tau [t-tau] and phosphorylated tau [p-tau]) in terms of diagnostic performance for Alzheimer disease (AD). MethodsWe compared t-tau and p-tau and 18F-AV-1451 in 30 controls, 14 patients with prodromal AD, and 39 patients with Alzheimer dement...
[ "Neuroscience and Disorders of the Nervous System", "Prevention, Diagnosis and Treatment of Human Diseases" ]
W971323507
Consumer Experiences with Credit Cards
This article examines consumers&amp;#x27; behavior, experiences, and attitudes regarding credit cards in the aftermath of the Great Recession and the implementation of the Credit Card Accountability Responsibility and Disclosure Act of 2009. The data for the article are primarily from a nationwide consumer survey spons...
[ "Individuals, Markets and Organisations", "The Social World and Its Interactions" ]
10.1002/mrm.26468
Probabilistic analysis of the specific absorption rate intersubject variability safety factor in parallel transmission MRI
Purpose: Specific absorption rate (SAR) calculations in parallel transmission are commonly performed by using electromagnetic simulations on generic models. In this study, we propose a probabilistic analysis to study the safety factor employed to account for SAR intersubject variability versus risk relationship in head...
[ "Physical and Analytical Chemical Sciences", "Systems and Communication Engineering" ]
10.1145/3064857.3079144
Runmerge Towards Enhanced Proprioception For Advanced Amateur Runners
While amateur running is one of the most popular recreational sport activities, it also produces many injuries, which are often caused by improper technique or shoe choice. In this paper, we present the design and initial evaluation of RunMerge - a mobile application that integrates data from location and motion sensor...
[ "Products and Processes Engineering", "Computer Science and Informatics" ]
10.1016/j.it.2017.02.007
The S(c)ensory Immune System Theory
Viewpoints on the immune system have evolved across different paradigms, including the clonal selection theory, the idiotypic network, and the danger and tolerance models. Herein, we propose that in multicellular organisms, where panoplies of cells from different germ layers interact and immune cells are constantly gen...
[ "Immunity, Infection and Immunotherapy", "Cell Biology, Development, Stem Cells and Regeneration", "Neuroscience and Disorders of the Nervous System" ]
306386
Specialisable, Programmable, Efficient and Robust Microprocessors
The development of faster, cheaper and smaller transistors has been the driving force behind the exponential growth in computing power over the past 50 years. While our ability to fabricate better transistors has not yet ceased, continuing to translate these advances into better system-level performance is now a major ...
[ "Computer Science and Informatics", "Systems and Communication Engineering" ]
10.1111/j.1365-2699.2012.02745.x
Connecting dynamic vegetation models to data - an inverse perspective
Dynamic vegetation models provide process-based explanations of the dynamics and the distribution of plant ecosystems. They offer significant advantages over static, correlative modelling approaches, particularly for ecosystems that are outside their equilibrium due to global change or climate change. A persistent prob...
[ "Earth System Science", "Environmental Biology, Ecology and Evolution", "Mathematics" ]